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JOURNAL ARTICLE
Samik S Partha, Sara M Malone, Melissa Bizzle, Geoffrey Ikpeama, Patrick J Reich, Carly R Schuetz, Stephanie A Fritz
OBJECTIVE: To understand healthcare worker (HCW) perceptions surrounding Staphylococcus aureus transmission and prevention in the neonatal intensive care unit (NICU). DESIGN: Qualitative case study with focus groups. SETTING: A level IV, 150-bed NICU at a Midwestern academic medical center that conducts active surveillance and decolonization of S. aureus- positive patients. PARTICIPANTS: NICU HCWs, including bedside nurses, nurse managers, therapy services personnel, pediatric nurse practitioners, clinical fellows, and attending neonatologists...
December 2023: Infection Control and Hospital Epidemiology
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JOURNAL ARTICLE
Peta-Anne Zimmerman, Jacqueline H Byrne, Brigid M Gillespie, Deborough Macbeth
BACKGROUND: Selection and use of personal protective equipment (PPE) to prevent non-percutaneous body fluid exposure (NP BFE) is determined by a clinical assessment of risk. The aim of this study was to explore the selection and use of PPE, particularly masks and eye protection to prevent NP BFE, by nurses. METHODS: This quantitative single-site two-phased study was guided by the Health Belief Model (HBM). Phase 1 was a retrospective electronic database audit of body fluid exposure surveillance data...
April 15, 2023: Infection, Disease & Health
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JOURNAL ARTICLE
Ivan O Rosas, Norbert Bräu, Michael Waters, Ronaldo C Go, Atul Malhotra, Bradley D Hunter, Sanjay Bhagani, Daniel Skiest, Sinisa Savic, Ivor S Douglas, Julia Garcia-Diaz, Mariam S Aziz, Nichola Cooper, Taryn Youngstein, Lorenzo Del Sorbo, David J De La Zerda, Andrew Ustianowski, Antonio Cubillo Gracian, Kevin G Blyth, Jordi Carratalà, Bruno François, Thomas Benfield, Derrick Haslem, Paolo Bonfanti, Cor H van der Leest, Nidhi Rohatgi, Lothar Wiese, Charles Edouard Luyt, Rebecca N Bauer, Fang Cai, Ivan T Lee, Balpreet Matharu, Louis Metcalf, Steffen Wildum, Emily Graham, Larry Tsai, Min Bao
Background: In COVACTA, a randomised, placebo-controlled trial in patients hospitalised with coronavirus disease-19 (COVID-19), tocilizumab did not improve 28-day mortality, but shortened hospital and intensive care unit stay. Longer-term effects of tocilizumab in patients with COVID-19 are unknown. Therefore, the efficacy and safety of tocilizumab in COVID-19 beyond day 28 and its impact on Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) clearance and antibody response in COVACTA were investigated...
May 2022: EClinicalMedicine
#4
JOURNAL ARTICLE
Inam Danish Khan, Geetanjali Gonimadatala, S Narayanan, Umesh Kapoor, Harleen Kaur, Anuradha Makkar, R M Gupta
Background: Device-associated infections (DAIs) such as ventilator associated pneumonia (VAP), central line-associated blood stream infection (CLABSI), and catheter-related urinary tract infection (CAUTI) are principal contributors to health hazard and a major preventable threat to patient safety. Robust surveillance of DAI delineates infections, pathogens, resistograms, and facilitates antimicrobial therapy, infection-control, antimicrobial stewardship, and improvement in quality of care...
April 2022: Medical Journal, Armed Forces India
#5
Wen-Jing Li, Chun-Ling Xue, Yong Zhang, Li-Hui Wu, Dong-Mei Chen, Feng Chen, Jing Xu, Zhuo Li, Hong-Jun Miao
Management of frequent epileptic seizures in febrile infection-related epilepsy (FIRES) is often challenging. FIRES is an uncommon disease condition. Children with FIRES develop refractory epilepsy with severe cognitive deficits that affect the function of the temporal and frontal lobes. However, better seizure control during the acute stage of FIRES could protect against injury to the nervous system. Ketogenic diet (KD) can effectively resolve super-refractory status epilepticus (SRSE) in the acute phase and improve the prognosis of FIRES...
September 2021: Translational Pediatrics
#6
JOURNAL ARTICLE
Peter Braun, Julian Braun, Barry G Woodcock
BACKGROUND: The characteristics of the COVID-19 pandemic in Europe have changed since the initial outbreak in 2019 due to the emergence of more contagious mutant strains, notably the B.1.1.7 variant. This has resulted in the rapid implementation of vaccination programs in an effort to control the spread of the disease. AIMS: To model the effect of vaccination on the course of the pandemic in Germany taking into account observational data and the appearance of viral mutant B...
June 15, 2021: International Journal of Clinical Pharmacology and Therapeutics
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JOURNAL ARTICLE
Yash Javeri, Ganshyam Jagathkar, Subhal Dixit, Dhruva Chaudhary, Kapil Gangadhar Zirpe, Yatin Mehta, Deepak Govil, Rajesh C Mishra, Srinivas Samavedam, Rahul Anil Pandit, Raymond Dominic Savio, Anuj M Clerk, Shrikanth Srinivasan, Deven Juneja, Sumit Ray, Tapas Kumar Sahoo, Srinivas Jakkinaboina, Nandhakishore Jampala, Ravi Jain
BACKGROUND AND PURPOSE: Short-term central venous catheterization (CVC) is one of the commonly used invasive interventions in ICU and other patient-care areas. Practice and management of CVC is not standardized, varies widely, and need appropriate guidance. Purpose of this document is to provide a comprehensive, evidence-based and up-to-date, one document source for practice and management of central venous catheterization. These recommendations are intended to be used by critical care physicians and allied professionals involved in care of patients with central venous lines...
January 2020: Indian Journal of Critical Care Medicine
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REVIEW
Feng Qin, Xinman Dou, Chenghua Mou, Fang Niu, Ruiling Nan, Yanhua Zhang, Chenming Dong, Jinhui Tian
OBJECTIVE: To evaluate the effectiveness of Percu Twist (PT) tracheostomy comparing with that of operative tracheostomy (OT) in intensive care unit (ICU). METHODS: Related data were retrieved from CBM, CNKI, Wanfang Data, VIP, PubMed, EMBASE, CENTRAL, and Web of Science from the time of their establishment to May 15th 2014, and the data of randomized controlled trials (RCTs) concerning PT and OT were selected. The risk of bias assessment and data extraction were performed by two independent reviewers...
December 2014: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
#9
JOURNAL ARTICLE
R W van den Berg, H L Claahsen, M Niessen, H L Muytjens, K Liem, A Voss
In the first week ot December 1997, an increasing incidence of neonates colonized with multi-drug resistant Enterobacter cloacae (MR-E. cloacae) was observed in the neonatal Intensive care unit of our 950-bed university hospital. Initially, re-enforcement of infection control practices including hand disinfection and cohort isolation seemed to be sufficient to control the outbreak. Nevertheless, an increasing number of newly admitted patients was paralleled by another rise in the incidence of colonized neonates...
May 2000: Journal of Hospital Infection
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