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low flow anaesthesia

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https://www.readbyqxmd.com/read/29181841/epidural-therapy-for-the-treatment-of-severe-pre-eclampsia-in-non-labouring-women
#1
REVIEW
Amita Ray, Sujoy Ray
BACKGROUND: Pre-eclampsia is a pregnancy-specific multi-organ disorder, which is characterised by hypertension and multisystem organ involvement and which has significant maternal and fetal morbidity and mortality. Failure of the placental vascular remodelling and reduced uteroplacental flow form the etiopathological basis of pre-eclampsia. There are several established therapies for pre-eclampsia including antihypertensives and anticonvulsants. Most of these therapies aim at controlling the blood pressure or preventing complications of elevated blood pressure, or both...
November 28, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29028917/comparative-usability-of-modern-anaesthesia-ventilators-a-human-factors-study
#2
J Spaeth, T Schweizer, A Schmutz, H Buerkle, S Schumann
Background: The anaesthesia ventilator represents the key equipment for intraoperative respiratory care. Improper operation of this device may threaten a patient's health. A self-explanatory interface facilitates handling and decreases the risk of operating errors. This study systematically evaluates the usability of user interfaces in four modern anaesthesia ventilators. Methods: Twenty naïve operators were asked to execute 20 tasks on each of four different anaesthesia ventilators (Avance CS2™, GE Healthcare; Flow-i™, Maquet; and Perseus™ and Primus™, Dräger) in a randomized order...
November 1, 2017: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/28910997/paediatric-nuclear-medicine-imaging
#3
Lorenzo Biassoni, Marina Easty
Background: Nuclear medicine imaging explores tissue viability and function by using radiotracers that are taken up at cellular level with different mechanism. This imaging technique can also be used to assess blood flow and transit through tubular organs. Nuclear medicine imaging has been used in paediatrics for decades and this field is continuously evolving. Sources of data: The data presented comes from clinical experience and some milestone papers on the subject...
September 1, 2017: British Medical Bulletin
https://www.readbyqxmd.com/read/28893018/changes-in-gas-composition-during-low-flow-anaesthesia-without-nitrous-oxide
#4
Ranjana Venkatachalapathy, Anusha Cherian, Sakthirajan Panneerselvam
INTRODUCTION: Low flow anaesthesia utilising Oxygen (O2) and Nitrous Oxide (N2O) mixture carries a risk of hypoxia, but avoiding N2O results in increased analgesic and volatile anaesthetic agent requirement. AIM: This study attempted to find the lowest Fraction of inspired Oxygen (FiO2) levels achieved with a mixture of 300 mL/min each of O2 and medical air over two hours and to compare the overall analgesic requirement and cost while using similar flows of N2O and O2, respectively...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28661230/circle-co2-reabsorbing-breathing-systems-human-applications
#5
Patrick Magee
Artificial breathing systems to help humans survive extreme environments are used over a range of ambient pressures, using various gases of different volumetric concentrations. These activities include anaesthesia and intensive care activity, high-altitude mountaineering, firefighting, aerospace extravehicular space activity and underwater diving operations. A circle breathing system is one in which the exhaled carbon dioxide is absorbed by an alkali substance and the remaining unused gases are recirculated, usually for the sake of economy and environment...
July 2017: Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine
https://www.readbyqxmd.com/read/28566410/postoperative-drug-induced-priapism
#6
Bartholomeus J G A Corten, Frits Aarts, Ansgar S Harms, Jeroen Vogelaar
We presented a case of a postoperative patient with low-flow priapism, possibly initiated by propofol-based anaesthesia or epidural anaesthesia. The delay in diagnosing priapism resulted in emergency interventions with a partially successful effect and eventually permanent erectile dysfunction. Due to the delay in treatment, erectile dysfunction ensued and was manageable with medication; hence, the patient decided against a penile prosthesis.
May 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28529707/wash-in-and-wash-out-of-sevoflurane-in-a-test-lung-model-a-comparison-between-aisys-and-flow-i
#7
Petter Jakobsson, Madleine Lindgren, Jan G Jakobsson
Background: Modern anaesthesia workstations are reassuringly tight and are equipped with effective gas monitoring, thus providing good opportunities for low/minimal flow anaesthesia. A prerequisite for effective low flow anaesthesia is the possibility to rapidly increase and decrease gas concentrations in the circle system, thereby controlling the depth of anaesthesia.  Methods: We studied the wash-in and wash-out of sevoflurane in the circle system with fixed fresh gas flow and vaporizer setting. We compared two modern anaesthesia work stations, the Aisys (GE, Madison, WI, USA) and FLOW-i (Maquet, Solna, Sweden) in a test lung model...
2017: F1000Research
https://www.readbyqxmd.com/read/28497164/metformin-prevents-ischaemic-ventricular-fibrillation-in-metabolically-normal-pigs
#8
Li Lu, Shuyu Ye, Rebecca L Scalzo, Jane E B Reusch, Clifford R Greyson, Gregory G Schwartz
AIMS/HYPOTHESIS: Metformin is the drug most often used to treat type 2 diabetes. Evidence suggests that metformin may reduce mortality of individuals with type 2 diabetes, but the mechanism of such an effect is unknown and outcomes of metformin treatment in people without diabetes have not been determined. If metformin favourably affected mortality of non-diabetic individuals, it might have even broader therapeutic utility. We evaluated the effect of metformin on myocardial energetics and ischaemic ventricular fibrillation (VF) in metabolically normal pigs...
August 2017: Diabetologia
https://www.readbyqxmd.com/read/28439441/comparison-of-effects-of-low-flow-sevoflurane-and-low-flow-desflurane-anaesthesia-on-renal-functions-using-cystatin-c
#9
Gökçen Duymaz, Seyhan Yağar, Ayşegül Özgök
OBJECTIVE: Numerous studies have indicated nephrotoxic effects of sevoflurane because of its two bioproducts compound A and fluoride. Cystatin C (CyC) is a more sensitive biomarker than creatinine to show early and mild changes in kidney function. We designed this prospective randomised study to compare the effects of low-flow sevoflurane anaesthesia and low-flow desflurane anaesthesia on renal functions based on CyC levels. No studies have evaluated the effects of low-flow sevoflurane anaesthesia on renal functions based on CyC levels to date...
April 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28410880/the-effect-of-user-experience-and-inflation-technique-on-endotracheal-tube-cuff-pressure-using-a-feline-airway-simulator
#10
Donna M White, José I Redondo, Alastair R Mair, Fernando Martinez-Taboada
OBJECTIVE: The effect of user experience and inflation technique on endotracheal tube cuff pressure using a feline airway simulator. STUDY DESIGN: Prospective, experimental clinical study. METHODS: Participants included veterinary students at the beginning (group S1) and end (group S2) of their 2-week anaesthesia rotation and veterinary anaesthetists (group A). The feline airway simulator was designed to simulate an average size feline trachea, intubated with a 4...
February 24, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28403017/effects-of-different-fresh-gas-flows-with-or-without-a-heat-and-moisture-exchanger-on-inhaled-gas-humidity-in-adults-undergoing-general-anaesthesia-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#11
José R C Braz, Mariana G Braz, Yoko Hayashi, Regina H G Martins, Marluci Betini, Leandro G Braz, Regina El Dib
BACKGROUND: The minimum inhaled gas absolute humidity level is 20 mgH2O l for short-duration use in general anaesthesia and 30 mgH2O l for long-duration use in intensive care to avoid respiratory tract dehydration. OBJECTIVE: The aim is to compare the effects of different fresh gas flows (FGFs) through a circle rebreathing system with or without a heat and moisture exchanger (HME) on inhaled gas absolute humidity in adults undergoing general anaesthesia. DESIGN: Systematic review and meta-analyses of randomised controlled trials...
August 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28375713/comparing-spinal-blockade-effectiveness-and-maternal-hemodynamics-using-25-gauge-and-29-gauge-spinal-needles-with-the-same-volumetric-flow-rate-in-patients-undergoing-caesarean-section
#12
Taner Ciftci, Hayrettin Daskaya, Serdar Efe
Spinal needles with different diameters can be used to prevent side effects in patients undergoing spinal anaesthesia. However, the velocity of local anaesthetic changes through the spinal needle depending on the diameter of it. Local anaesthetic injection velocity has been reported to be associated with the spinal block level. We aimed to compare spinal needles of different diameters with the same local anaesthetic volumetric flow rate in terms of spinal blockade and hemodynamics in obstetric patients. Eighty-four patients received spinal anaesthesia by either a 25G needle or 29G with the same volumetric flow rate...
August 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27761039/a-survey-on-the-use-of-low-flow-anaesthesia-and-the-choice-of-inhalational-anaesthetic-agents-among-anaesthesiologists-of-india
#13
Rajasree Omanakutty Amma, Subha Ravindran, Rachel Cherian Koshy, K M Jagathnath Krishna
BACKGROUND AND AIMS: With the availability of modern workstations and heightened awareness on the environmental effects of waste anaesthesia gases, anaesthesiologists worldwide are practicing low flow anaesthesia (LFA). Although LFA is being practiced in India, hard evidence on the current practice of the same from anaesthesiologists practicing in India is lacking and hence, we conducted this survey. METHODS: A questionnaire containing 16 questions was distributed among a subgroup of anaesthesiologists who attended the 2014 National Conference of Indian Society of Anaesthesiologists...
October 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27632682/single-intravenous-dose-of-novel-flurbiprofen-loaded-proniosome-formulations-provides-prolonged-systemic-exposure-and-anti-inflammatory-effect
#14
Preeti Verma, Sunil K Prajapati, Rajbharan Yadav, Danielle Senyschyn, Peter R Shea, Natalie L Trevaskis
Vesicular and colloidal delivery systems can be designed to control drug release spatially and temporally to improve drug efficacy and side effect profiles. Niosomes (vesicles prepared from nonionic surfactants in aqueous media) are gaining interest as an alternative vesicular delivery system as they offer advantages such as biocompatibility, chemical stability, low cost, high purity, and versatility. However, the physical stability of niosomes, like other vesicular systems, is limited by vesicle fusion, aggregation, and leakage...
November 7, 2016: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/27338523/criteria-for-choosing-an-intravenous-infusion-line-intended-for-multidrug-infusion-in-anaesthesia-and-intensive-care-units
#15
REVIEW
Aurélie Maiguy-Foinard, Stéphanie Genay, Damien Lannoy, Christine Barthélémy, Gilles Lebuffe, Bertrand Debaene, Pascal Odou, Bertrand Décaudin
OBJECTIVE: The aims are to identify critical parameters influencing the drug mass flow rate of infusion delivery to patients during multidrug infusion and to discuss their clinical relevance. DATA SOURCES: A review of literature was conducted in January 2016 using Medline, Google Scholar, ScienceDirect, Web of Science and Scopus online databases. DATA EXTRACTION: References relating to the accuracy of fluid delivery via gravity-flow intravenous (IV) infusion systems and positive displacement pumps, components of IV administration sets, causes of flow rate variability, potential complications due to flow rate variability, IV therapies especially at low flow rates and drug compatibilities were considered relevant...
February 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/27164016/inhaled-anaesthetics-and-nitrous-oxide-complexities-overlooked-things-may-not-be-what-they-seem
#16
Jan Hendrickx, Philip Peyton, Rik Carette, Andre De Wolf
This review re-examines existing pharmacokinetic and pharmacodynamic concepts of inhaled anaesthetics. After showing where uptake is hidden in the classic FA/FI curve, it is argued that target-controlled delivery of inhaled agents warrants a different interpretation of the factors affecting this curve (cardiac output, ventilation and blood/gas partition coefficient). Blood/gas partition coefficients of modern agents may be less important clinically than generally assumed. The partial pressure cascade from delivered to inspired to end-expired is re-examined to better understand the effect of rebreathing during low-flow anaesthesia, including the possibility of developing a hypoxic inspired mixture despite existing machine standards...
September 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/26846332/the-trilateral-link-between-anaesthesia-perioperative-visual-loss-and-flammer-syndrome
#17
Rossiana I Bojinova, Katarzyna Konieczka, Peter Meyer, Margarita G Todorova
BACKGROUND: A variety of factors have been linked to perioperative visual loss during or directly after nonocular and ocular surgeries. Prolonged immobilization, biochemical factors and hemodynamic instability have been discussed as factors in the pathogenesis of this devastating complication. Perioperative visual loss in four consecutive patients, all featuring Flammer syndrome, is reported herein. To our knowledge, we present the first case series, which associates perioperative visual loss with Flammer syndrome...
February 4, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/26688296/a-simple-method-for-isocapnic-hyperventilation-evaluated-in-a-lung-model
#18
K Hallén, O Stenqvist, S-E Ricksten, S Lindgren
BACKGROUND: Isocapnic hyperventilation (IHV) has the potential to increase the elimination rate of anaesthetic gases and has been shown to shorten time to wake-up and post-operative recovery time after inhalation anaesthesia. In this bench test, we describe a technique to achieve isocapnia during hyperventilation (HV) by adding carbon dioxide (CO2) directly to the breathing circuit of a standard anaesthesia apparatus with standard monitoring equipment. METHODS: Into a mechanical lung model, carbon dioxide was added to simulate a CO2 production (V(CO2)) of 175, 200 and 225 ml/min...
May 2016: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/26643095/modes-of-mechanical-ventilation-for-the-operating-room
#19
REVIEW
Lorenzo Ball, Maddalena Dameri, Paolo Pelosi
Most patients undergoing surgical procedures need to be mechanically ventilated, because of the impact of several drugs administered at induction and during maintenance of general anaesthesia on respiratory function. Optimization of intraoperative mechanical ventilation can reduce the incidence of post-operative pulmonary complications and improve the patient's outcome. Preoxygenation at induction of general anaesthesia prolongs the time window for safe intubation, reducing the risk of hypoxia and overweighs the potential risk of reabsorption atelectasis...
September 2015: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/26333199/sialendoscopy-in-sialadenitis-an-unselected-cohort-of-228-patients
#20
LETTER
J Jokela, A Haapaniemi, J Ojala, A Mäkitie, R Saarinen
No abstract text is available yet for this article.
August 2016: Clinical Otolaryngology
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