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low flow anaesthesia

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https://www.readbyqxmd.com/read/28439441/comparison-of-effects-of-low-flow-sevoflurane-and-low-flow-desflurane-anaesthesia-on-renal-functions-using-cystatin-c
#1
Gökçen Duymaz, Seyhan Yağar, Ayşegül Özgök
OBJECTIVE: Numerous studies have indicated nephrotoxic effects of sevoflurane because of its two bioproducts compound A and fluoride. Cystatin C (CyC) is a more sensitive biomarker than creatinine to show early and mild changes in kidney function. We designed this prospective randomised study to compare the effects of low-flow sevoflurane anaesthesia and low-flow desflurane anaesthesia on renal functions based on CyC levels. No studies have evaluated the effects of low-flow sevoflurane anaesthesia on renal functions based on CyC levels to date...
April 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28410880/the-effect-of-user-experience-and-inflation-technique-on-endotracheal-tube-cuff-pressure-using-a-feline-airway-simulator
#2
Donna M White, José I Redondo, Alastair R Mair, Fernando Martinez-Taboada
OBJECTIVE: The effect of user experience and inflation technique on endotracheal tube cuff pressure using a feline airway simulator. STUDY DESIGN: Prospective, experimental clinical study. METHODS: Participants included veterinary students at the beginning (group S1) and end (group S2) of their 2-week anaesthesia rotation and veterinary anaesthetists (group A). The feline airway simulator was designed to simulate an average size feline trachea, intubated with a 4...
February 24, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28403017/effects-of-different-fresh-gas-flows-with-or-without-a-heat-and-moisture-exchanger-on-inhaled-gas-humidity-in-adults-undergoing-general-anaesthesia-a-systematic-review-and-meta-analysis-of-randomised-controlled-trials
#3
José R C Braz, Mariana G Braz, Yoko Hayashi, Regina H G Martins, Marluci Betini, Leandro G Braz, Regina El Dib
BACKGROUND: The minimum inhaled gas absolute humidity level is 20 mgH2O l for short-duration use in general anaesthesia and 30 mgH2O l for long-duration use in intensive care to avoid respiratory tract dehydration. OBJECTIVE: The aim is to compare the effects of different fresh gas flows (FGFs) through a circle rebreathing system with or without a heat and moisture exchanger (HME) on inhaled gas absolute humidity in adults undergoing general anaesthesia. DESIGN: Systematic review and meta-analyses of randomised controlled trials...
April 11, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28375713/comparing-spinal-blockade-effectiveness-and-maternal-hemodynamics-using-25-gauge-and-29-gauge-spinal-needles-with-the-same-volumetric-flow-rate-in-patients-undergoing-caesarean-section
#4
Taner Ciftci, Hayrettin Daskaya, Serdar Efe
Spinal needles with different diameters can be used to prevent side effects in patients undergoing spinal anaesthesia. However, the velocity of local anaesthetic changes through the spinal needle depending on the diameter of it. Local anaesthetic injection velocity has been reported to be associated with the spinal block level. We aimed to compare spinal needles of different diameters with the same local anaesthetic volumetric flow rate in terms of spinal blockade and hemodynamics in obstetric patients. Eighty-four patients received spinal anaesthesia by either a 25G needle or 29G with the same volumetric flow rate...
April 4, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27761039/a-survey-on-the-use-of-low-flow-anaesthesia-and-the-choice-of-inhalational-anaesthetic-agents-among-anaesthesiologists-of-india
#5
Rajasree Omanakutty Amma, Subha Ravindran, Rachel Cherian Koshy, K M Jagathnath Krishna
BACKGROUND AND AIMS: With the availability of modern workstations and heightened awareness on the environmental effects of waste anaesthesia gases, anaesthesiologists worldwide are practicing low flow anaesthesia (LFA). Although LFA is being practiced in India, hard evidence on the current practice of the same from anaesthesiologists practicing in India is lacking and hence, we conducted this survey. METHODS: A questionnaire containing 16 questions was distributed among a subgroup of anaesthesiologists who attended the 2014 National Conference of Indian Society of Anaesthesiologists...
October 2016: Indian Journal of Anaesthesia
https://www.readbyqxmd.com/read/27632682/single-intravenous-dose-of-novel-flurbiprofen-loaded-proniosome-formulations-provides-prolonged-systemic-exposure-and-anti-inflammatory-effect
#6
Preeti Verma, Sunil K Prajapati, Rajbharan Yadav, Danielle Senyschyn, Peter R Shea, Natalie L Trevaskis
Vesicular and colloidal delivery systems can be designed to control drug release spatially and temporally to improve drug efficacy and side effect profiles. Niosomes (vesicles prepared from nonionic surfactants in aqueous media) are gaining interest as an alternative vesicular delivery system as they offer advantages such as biocompatibility, chemical stability, low cost, high purity, and versatility. However, the physical stability of niosomes, like other vesicular systems, is limited by vesicle fusion, aggregation, and leakage...
November 7, 2016: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/27338523/criteria-for-choosing-an-intravenous-infusion-line-intended-for-multidrug-infusion-in-anaesthesia-and-intensive-care-units
#7
REVIEW
Aurélie Maiguy-Foinard, Stéphanie Genay, Damien Lannoy, Christine Barthélémy, Gilles Lebuffe, Bertrand Debaene, Pascal Odou, Bertrand Décaudin
OBJECTIVE: The aims are to identify critical parameters influencing the drug mass flow rate of infusion delivery to patients during multidrug infusion and to discuss their clinical relevance. DATA SOURCES: A review of literature was conducted in January 2016 using Medline, Google Scholar, ScienceDirect, Web of Science and Scopus online databases. DATA EXTRACTION: References relating to the accuracy of fluid delivery via gravity-flow intravenous (IV) infusion systems and positive displacement pumps, components of IV administration sets, causes of flow rate variability, potential complications due to flow rate variability, IV therapies especially at low flow rates and drug compatibilities were considered relevant...
February 2017: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/27164016/inhaled-anaesthetics-and-nitrous-oxide-complexities-overlooked-things-may-not-be-what-they-seem
#8
Jan Hendrickx, Philip Peyton, Rik Carette, Andre De Wolf
This review re-examines existing pharmacokinetic and pharmacodynamic concepts of inhaled anaesthetics. After showing where uptake is hidden in the classic FA/FI curve, it is argued that target-controlled delivery of inhaled agents warrants a different interpretation of the factors affecting this curve (cardiac output, ventilation and blood/gas partition coefficient). Blood/gas partition coefficients of modern agents may be less important clinically than generally assumed. The partial pressure cascade from delivered to inspired to end-expired is re-examined to better understand the effect of rebreathing during low-flow anaesthesia, including the possibility of developing a hypoxic inspired mixture despite existing machine standards...
September 2016: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/26846332/the-trilateral-link-between-anaesthesia-perioperative-visual-loss-and-flammer-syndrome
#9
Rossiana I Bojinova, Katarzyna Konieczka, Peter Meyer, Margarita G Todorova
BACKGROUND: A variety of factors have been linked to perioperative visual loss during or directly after nonocular and ocular surgeries. Prolonged immobilization, biochemical factors and hemodynamic instability have been discussed as factors in the pathogenesis of this devastating complication. Perioperative visual loss in four consecutive patients, all featuring Flammer syndrome, is reported herein. To our knowledge, we present the first case series, which associates perioperative visual loss with Flammer syndrome...
February 4, 2016: BMC Anesthesiology
https://www.readbyqxmd.com/read/26688296/a-simple-method-for-isocapnic-hyperventilation-evaluated-in-a-lung-model
#10
K Hallén, O Stenqvist, S-E Ricksten, S Lindgren
BACKGROUND: Isocapnic hyperventilation (IHV) has the potential to increase the elimination rate of anaesthetic gases and has been shown to shorten time to wake-up and post-operative recovery time after inhalation anaesthesia. In this bench test, we describe a technique to achieve isocapnia during hyperventilation (HV) by adding carbon dioxide (CO2) directly to the breathing circuit of a standard anaesthesia apparatus with standard monitoring equipment. METHODS: Into a mechanical lung model, carbon dioxide was added to simulate a CO2 production (V(CO2)) of 175, 200 and 225 ml/min...
May 2016: Acta Anaesthesiologica Scandinavica
https://www.readbyqxmd.com/read/26643095/modes-of-mechanical-ventilation-for-the-operating-room
#11
REVIEW
Lorenzo Ball, Maddalena Dameri, Paolo Pelosi
Most patients undergoing surgical procedures need to be mechanically ventilated, because of the impact of several drugs administered at induction and during maintenance of general anaesthesia on respiratory function. Optimization of intraoperative mechanical ventilation can reduce the incidence of post-operative pulmonary complications and improve the patient's outcome. Preoxygenation at induction of general anaesthesia prolongs the time window for safe intubation, reducing the risk of hypoxia and overweighs the potential risk of reabsorption atelectasis...
September 2015: Best Practice & Research. Clinical Anaesthesiology
https://www.readbyqxmd.com/read/26333199/sialendoscopy-in-sialadenitis-an-unselected-cohort-of-228-patients
#12
LETTER
J Jokela, A Haapaniemi, J Ojala, A Mäkitie, R Saarinen
No abstract text is available yet for this article.
August 2016: Clinical Otolaryngology
https://www.readbyqxmd.com/read/26313101/funding-flows-to-global-surgery-an-analysis-of-contributions-from-the-usa
#13
Lily A Gutnik, Joseph Dielman, Anna J Dare, Margarita S Ramos, Robert Riviello, John G Meara, Gavin Yamey, Mark G Shrime
BACKGROUND: In recent years, funds for global health have risen substantially, particularly for infectious diseases. Although conditions amenable to surgery account for 28% of the global burden of disease, the external funds directed towards global surgical delivery, capacity building, and research are currently unknown and presumed to be low. We aimed to describe external funds given to these efforts from the USA, the world's largest donor nation. METHODS: We searched the United States Agency for International Development (USAID), National Institute of Health (NIH), Foundation Center, and registered US charitable organisations databases for financial data on any giving exclusively to surgical care in low-income and middle-income countries (LMICs)...
April 27, 2015: Lancet
https://www.readbyqxmd.com/read/26253608/optimizing-oxygenation-and-intubation-conditions-during-awake-fibre-optic-intubation-using-a-high-flow-nasal-oxygen-delivery-system
#14
S Badiger, M John, R A Fearnley, I Ahmad
BACKGROUND: Awake fibre-optic intubation is a widely practised technique for anticipated difficult airway management. Despite the administration of supplemental oxygen during the procedure, patients are still at risk of hypoxia because of the effects of sedation, local anaesthesia, procedural complications, and the presence of co-morbidities. Traditionally used oxygen-delivery devices are low flow, and most do not have a sufficient reservoir or allow adequate fresh gas flow to meet the patient's peak inspiratory flow rate, nor provide an adequate fractional inspired oxygen concentration to prevent desaturation should complications arise...
October 2015: British Journal of Anaesthesia
https://www.readbyqxmd.com/read/26207980/fetal-growth-restriction-and-intra-uterine-growth-restriction-guidelines-for-clinical-practice-from-the-french-college-of-gynaecologists-and-obstetricians
#15
C Vayssière, L Sentilhes, A Ego, C Bernard, D Cambourieu, C Flamant, G Gascoin, A Gaudineau, G Grangé, V Houfflin-Debarge, B Langer, V Malan, P Marcorelles, J Nizard, F Perrotin, L Salomon, M-V Senat, A Serry, V Tessier, P Truffert, V Tsatsaris, C Arnaud, B Carbonne
Small for gestational age (SGA) is defined by weight (in utero estimated fetal weight or birth weight) below the 10th percentile (professional consensus). Severe SGA is SGA below the third percentile (professional consensus). Fetal growth restriction (FGR) or intra-uterine growth restriction (IUGR) usually correspond with SGA associated with evidence indicating abnormal growth (with or without abnormal uterine and/or umbilical Doppler): arrest of growth or a shift in its rate measured longitudinally (at least two measurements, 3 weeks apart) (professional consensus)...
October 2015: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/26198766/desflurane-and-sevoflurane-use-during-low-and-minimal-flow-anesthesia-at-fixed-vaporizer-settings
#16
Maria Horwitz, Jan G Jakobsson
BACKGROUND: The pharmacokinetics for sevoflurane and desflurane makes them suitable for low-flow anesthesia. The aim of the present study was to assess the use of desflurane and sevoflurane at constant vaporizer settings and fixed low fresh gas flows. METHODS: One hundred ASA 1-2 patients undergoing elective laparoscopic surgery were randomized into 4 groups (25 patients each): a fixed fresh gas flow 1.0 or 0.5 L/min with desflurane (D1.0 and D0.5) or sevoflurane (S1...
February 2016: Minerva Anestesiologica
https://www.readbyqxmd.com/read/26001691/endometrial-ablation-in-the-management-of-abnormal-uterine-bleeding
#17
Philippe Laberge, Nicholas Leyland, Ally Murji, Claude Fortin, Paul Martyn, George Vilos, Nicholas Leyland, Wendy Wolfman, Catherine Allaire, Alaa Awadalla, Sheila Dunn, Mark Heywood, Madeleine Lemyre, Violaine Marcoux, Frank Potestio, David Rittenberg, Sukhbir Singh, Grace Yeung
BACKGROUND: Abnormal uterine bleeding (AUB) is the direct cause of a significant health care burden for women, their families, and society as a whole. Up to 30% of women will seek medical assistance for the problem during their reproductive years. OBJECTIVE: To provide current evidence-based guidelines on the techniques and technologies used in endometrial ablation (EA), a minimally invasive technique for the management of AUB of benign origin. METHODS: Members of the guideline committee were selected on the basis of individual expertise to represent a range of practical and academic experience in terms of both location in Canada and type of practice, as well as subspecialty expertise and general background in gynaecology...
April 2015: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/25952751/evaluation-of-total-oxidant-and-antioxidant-status-in-dogs-under-different-co2-pneumoperitoneum-conditions
#18
Jae Yeon Lee, Seok Hwa Choi
BACKGROUND: The induction of the pneumoperitoneum increases intraabdominal pressure (IAP), causing splanchnic ischemia, whereas its deflation normalizes IAP and splanchnic blood flow. We investigated the oxidant-antioxidant status of dogs who underwent low pressure (7 mm Hg), standard pressure (12 mm Hg), and high pressure (15 mm Hg) pneumoperitoneum. RESULTS: Twenty-four beagle dogs (12 males and 12 females), 4-6 years old, weighing 8-11 kg were used. The animals were assigned to one of four groups (n = 6 dogs)...
2015: Acta Veterinaria Scandinavica
https://www.readbyqxmd.com/read/25912157/alertness-opens-the-effective-flow-of-sensory-information-through-rat-thalamic-posterior-nucleus
#19
Aleksander Sobolewski, Ewa Kublik, Daniel A Swiejkowski, Jan Kamiński, Andrzej Wróbel
Behavioural reactions to sensory stimuli vary with the level of arousal, but little is known about the underlying reorganization of neuronal networks. In this study, we use chronic recordings from the somatosensory regions of the thalamus and cortex of behaving rats together with a novel analysis of functional connectivity to show that during low arousal tactile signals are transmitted via the ventral posteromedial thalamic nucleus (VPM), a first-order thalamic relay, to the primary somatosensory (barrel) cortex and then from the cortex to the posterior medial thalamic nucleus (PoM), which plays a role of a higher-order thalamic relay...
May 2015: European Journal of Neuroscience
https://www.readbyqxmd.com/read/25530758/cost-analysis-of-three-techniques-of-administering-sevoflurane
#20
Asha Tyagi, Vineeta Venkateswaran, Ajai Kumar Jain, Uttam Chandra Verma
Background. This study aimed to evaluate and compare total cost of sevoflurane and propofol for 1.0 MAC-hour of anaesthesia, employing three anaesthetic techniques. Methods. Adult patients scheduled for surgical procedures under general anaesthesia anticipated to last approximately an hour were randomized into three groups (n = 15 each), to receive anaesthesia using one of the following techniques: low flow technique involving induction with propofol, followed by sevoflurane delivered using initial fresh gas flows of 6 L/min till MAC reached 1...
2014: Anesthesiology Research and Practice
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