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https://www.readbyqxmd.com/read/28719009/diagnosis-of-chronic-heart-failure-by-the-soluble-suppression-of-tumorigenicity-2-and-n-terminal-pro-brain-natriuretic-peptide
#1
Xiao-Ling Jin, Ning Huang, Hui Shang, Ming-Cheng Zhou, Yi Hong, Wen-Zheng Cai, Jie Huang
OBJECTIVE: Our study was to explore the roles between serum soluble suppression of tumorigenicity 2 (sST2) and N-terminal pro-brain natriuretic peptide (NT-proBNP) while evaluating ventricular function to properly diagnose chronic heart failure (CHF). METHODS: In total, 197 CHF patients were recruited and classified into ventricular function's II, III, and IV groups, and 106 healthy people into normal control group. To detect concentrations of Sst2 and NT-proBNP, ELISA and electro-chemiluminescence immuno assay were implemented...
July 18, 2017: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/28716185/pitavastatin-and-hdl-effects-on-plasma-levels-and-function-s
#2
REVIEW
Angela Pirillo, Alberico L Catapano
Low high density lipoprotein cholesterol (HDL-C) levels represent an independent risk factor for cardiovascular disease; in addition to the reduced HDL-C levels commonly observed in patients at cardiovascular risk, the presence of dysfunctional HDL, i.e. HDL with reduced atheroprotective properties, has been reported. Despite the established inverse correlation between HDL-C levels and cardiovascular risk, several clinical trials with HDL-C-increasing drugs (such as niacin, CETP inhibitors or fibrate) failed to demonstrate that a significant rise in HDL-C levels translate into a cardiovascular benefit...
July 2017: Atherosclerosis. Supplements
https://www.readbyqxmd.com/read/28715884/association-of-daily-physical-activity-level-with-health-related-factors-by-gender-and-age-specific-differences-among-korean-adults-based-on-the-sixth-2014-2015-korea-national-health-and-nutrition-examination-survey
#3
Nana Chung, Hun-Young Park, Mi-Young Park, Yoon-Young Hwang, Chi-Ho Lee, Jin-Soo Han, Jaemoo So, Jisu Kim, Jonghoon Park, Kiwon Lim
PURPOSE: This study examined the effects of daily physical activity level on health-related factors according to gender and identified age-specific differences among Korean adults. METHODS: Using data from the Korea National Health and Nutrition Examination Survey VI (2014-2015), we selected adults aged 19-64 years who participated in both a health examination and health interview survey. The study included 6,457 participants 19-64 years of age (2,611 men, 3,846 women)...
June 30, 2017: Journal of Exercise Nutrition & Biochemistry
https://www.readbyqxmd.com/read/28712165/effectiveness-of-a-school-based-multicomponent-intervention-on-nutritional-status-among-primary-school-children-in-bangkok-thailand
#4
Nattapon Chawla, Alessio Panza, Chutima Sirikulchayanonta, Ramesh Kumar, Surasak Taneepanichskul
BACKGROUND: Childhood obesity has become a major public health issue today. The prevalence of obesity and overweight is increasing in both adults and children. Childhood obesity in Thailand has more than doubled since the 1960s and a recent study reported that overweight and obesity in Thais is the 5th highest in Asia. The present study objective was to evaluate the effectiveness of a life-skills, multicomponent, school-based intervention on child nutritional status. METHODS: A quasi-experimental design was conducted in two-groups (control and intervention schools) on 453 students attending grade levels 4-5 in Bangkok...
January 2017: Journal of Ayub Medical College, Abbottabad: JAMC
https://www.readbyqxmd.com/read/28712073/association-between-ace-and-agt-polymorphism-and-cardiovascular-risk-in-acromegalic-patients
#5
Tomris Erbas, Nese Cinar, Selcuk Dagdelen, Arzu Gedik, Hikmet Yorgun, Ugur Canpolat, Giray Kabakci, Mehmet Alikasifoglu
PURPOSE: Whether the renin-angiotensin-aldosterone system plays a role or not in the development of cardiovascular morbidity in acromegaly patients is unknown. The aim of the study was to investigate the association between ACE (I/D) and AGT (M235T) gene polymorphisms and cardiovascular and metabolic disorders in the acromegaly. METHODS: The study included one hundred and seventeen acromegalic patients (62 F/55 M, age: 50.2 ± 12.3 years) and 106 healthy controls (92 F/14 M, age: 41...
July 15, 2017: Pituitary
https://www.readbyqxmd.com/read/28711515/longitudinal-changes-in-visceral-and-subcutaneous-adipose-tissue-and-metabolic-syndrome-results-from-the-multicultural-community-health-assessment-trial-m-chat
#6
Andrew W Tu, Karin H Humphries, Scott A Lear
AIM: Few studies have examined whether longitudinal changes in visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT), independent of each other, are associated with the risk of developing metabolic syndrome (MetS). The objective of this study was to examine the longitudinal effects of VAT and SAT on MetS and metabolic risk factors in a multi-ethnic sample of Canadians followed for 5-years. MATERIALS AND METHODS: In total, 598 adults of the Multicultural Community Health Assessment Trial (M-CHAT) were included in this study...
July 8, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/28709820/sex-dependent-difference-in-the-relationship-between-adipose-tissue-cholesterol-efflux-and-estradiol-concentrations-in-young-healthy-humans
#7
REVIEW
Fatima Iqbal, William J Durham, Ayyash Melhem, Saleem Raslan, Tony T Tran, Traver J Wright, Rabia Asghar, Ken Fujise, Elena Volpi, Labros Sidossis, Nicola Abate, Melinda Sheffield-Moore, Demidmaa Tuvdendorj
BACKGROUND: Impaired adipose tissue function and lower levels of high density lipoprotein cholesterol (HDL-C) have been implicated in the development of vascular dementia, and metabolic diseases such as hypertension, atherosclerosis, type 2 diabetes (T2D) and metabolic syndrome. Interestingly, both the substrate fluxes in adipose tissue and HDL-C concentration differ between men and women. Moreover, adipose tissue cholesterol efflux has been implicated in modulation of HDL-C levels. Thus, we aimed to determine if the association between serum estradiol levels and adipose tissue cholesterol efflux is sex-dependent...
July 11, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28707864/oxidative-stress-antioxidants-and-lipid-profile-in-the-serum-and-saliva-of-individuals-with-coronary-heart-disease-is-there-a-link-with-periodontal-health
#8
Natheer H Al-Rawi, Alaa M Shahid
BACKGROUND: Oxidative stresses and dyslipidemia are an important risk factor in the development of coronary atherosclerotic complications like angina pectoris and myocardial infarction. The aim of this study was to find the relationship between the salivary lipid profile, lipid peroxidation and antioxidants and the periodontal health status of patients with acute coronary heart disease. METHODS: Forty s who had experienced a recent attack of angina pectoris or myocardial infarction and another 40 noncardiac patients matched for age, sex and residence (control) were recruited...
July 12, 2017: Minerva Stomatologica
https://www.readbyqxmd.com/read/28707319/tenofovir-disoproxil-fumarate-significantly-decreases-serum-lipoprotein-levels-compared-with-entecavir-nucleos-t-ide-analogue-therapy-in-chronic-hepatitis-b-carriers
#9
A A Shaheen, M AlMattooq, S Yazdanfar, K W Burak, M G Swain, S E Congly, M A Borman, S S Lee, R P Myers, C S Coffin
BACKGROUND: Tenofovir disoproxil fumarate (TDF) and entecavir (ETV) are first-line treatments for chronic hepatitis B (CHB). Studies suggest lipid lowering effect of TDF in human immunodeficiency virus positive (HIV+) individuals, but the effect on lipids and cardiovascular disease (CVD) risk in CHB is unknown. AIM: To compare TDF vs ETV effects on lipid levels in CHB. METHODS: In this retrospective cohort study, data on serum lipids and CVD risk factors at baseline and ~1 year on TDF or ETV were collected from CHB carriers...
July 13, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28704507/regular-moist-snuff-dipping-does-not-affect-endurance-exercise-performance
#10
Frida Björkman, Fredrik Edin, C Mikael Mattsson, Filip Larsen, Björn Ekblom
Physiological and medical effects of snuff have previously been obtained either in cross-sectional studies or after snuff administration to non-tobacco users. The effects of snuff cessation after several years of daily use are unknown. 24 participants with >2 years of daily snuff-use were tested before and after >6 weeks snuff cessation (SCG). A control group (CO) of 11 snuff users kept their normal habits. Resting heart rate (HR) and blood pressure (BP) were significantly lower in SCG after snuff cessation, and body mass was increased by 1...
2017: PloS One
https://www.readbyqxmd.com/read/28701632/clinical-features-and-gaps-in-the-management-of-probable-familial-hypercholesterolemia-and-cardiovascular-disease
#11
Barak Zafrir, Ayman Jubran, Gil Lavie, David A Halon, Moshe Y Flugelman, Chen Shapira
BACKGROUND: Familial hypercholesterolemia (FH) is associated with premature atherosclerotic cardiovascular disease (ASCVD). The introduction of potent therapeutic agents underlies the importance of improving clinical diagnosis and treatment gaps in FH.Methods and Results:A regional database of 1,690 adult patients with high-probability FH based on age-dependent peak-low-density lipoprotein cholesterol (LDL-C) cut-offs and exclusion of secondary causes of severe hypercholesterolemia, was examined to explore the clinical manifestations and current needs in the management of ASCVD, which was present in 248 patients (15%), of whom 83% had coronary artery disease (CAD); 19%, stroke; and 13%, peripheral artery disease...
July 12, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/28701179/a-study-on-relationship-between-elderly-sarcopenia-and-inflammatory-factors-il-6-and-tnf-%C3%AE
#12
Ai-Lin Bian, Hui-Ying Hu, Yu-Dong Rong, Jian Wang, Jun-Xiong Wang, Xin-Zi Zhou
BACKGROUND: This report aims to study the relationship between sarcopenia of elderly in community and inflammatory factors IL-6 and TNF-α. METHODS: A total of 441 elders who undertook physical examinations were included into this study. The age of these subjects were >60, in which 235 subjects were male and 206 subjects were female. According to the diagnostic standards of sarcopenia set by EWGSOP and AWGS, these subjects were divided into two groups: sarcopenia, and non-sarcopenia groups...
July 12, 2017: European Journal of Medical Research
https://www.readbyqxmd.com/read/28700358/antihyperglycemic-treatment-in-patients-with-type-2-diabetes-in-italy-the-impact-of-age-and-kidney-function
#13
Sandro Gentile, Pamela Piscitelli, Francesca Viazzi, Giuseppina Russo, Antonio Ceriello, Carlo Giorda, Piero Guida, Paola Fioretto, Roberto Pontremoli, Felice Strollo, Salvatore De Cosmo, The Amd-Annals Study Group
We describe AHA utilization pattern according to age and renal function in type 2 diabetes mellitus (T2DM), in real-life conditions.The analysis was performed using the data set of electronic medical records collected between 1 January and 31 December, 2011 in 207 Italian diabetes centers. The study population consisted of 157,595 individuals with T2DM. The AHA treatment regimens was evaluated. Kidney function was assessed by eGFR, estimated using the CKD-EPI formula. Other determinations: HbA1c, blood pressure (BP), low- density lipoprotein (LDL-c), total and high density lipoprotein cholesterol (TC and HDL-c), triglycerides (TG) and serum uric acid (SUA)...
June 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28700017/plasma-total-antioxidant-capacity-and-cardiometabolic-risk-in-non-obese-and-clinically-healthy-young-adults
#14
Jamille Oliveira Costa, Cecília M Passos Vásquez, Gleiciane de Jesus Santana, Natanael de Jesus Silva, Juciene de Matos Braz, Amélia M Ribeiro de Jesus, Danielle Góes da Silva, Luana Celina Seraphim Cunha, Kiriaque Barra Ferreira Barbosa
Background: The oxidative biomarkers play an important role in the genesis of cardiometabolic risk-related processes. Objective: To investigate the total antioxidant capacity of plasma and its association with cardiometabolic risk in non-obese and clinically healthy young adults. Methods: University students of the state of Sergipe, Brazil, aged between 18 and 25 years, were recruited for this study from May of 2013 and October of 2014. Anthropometric, clinical and biochemical parameters were measured and analyzed using protocols which were previously standardized and described in the literature...
July 10, 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28699976/discordant-lipid-pattern-and-carotid-atherosclerotic-plaque-importance-of-remnant-cholesterol
#15
Walter Masson, Martín Lobo, Graciela Molinero, Daniel Siniawski
Background: Subjects with levels of non-HDL-C 30 mg/dL above those of LDL-C (lipid discordance) or with high remnant cholesterol levels could have a greater residual cardiovascular risk. Objectives: To determine the prevalence of lipid discordance in a primary prevention population and analyze the clinical variables associated with it; To investigate the association between lipid discordance and remnant cholesterol with the presence of carotid plaque. Methods: Primary prevention patients without diabetes or lipid-lowering therapy were included...
June 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28695324/the-effect-of-almonds-on-vitamin-e-status-and-cardiovascular-risk-factors-in-korean-adults-a-randomized-clinical-trial
#16
Hana Jung, C-Y Oliver Chen, Jeffrey B Blumberg, Ho-Kyung Kwak
PURPOSE: Almonds have shown to beneficially modify some cardiovascular risk factors in clinical trials conducted in diverse ethnic populations but this relationship has never been tested in Koreans. Thus, we tested the impact of almonds consumed as a snack within the context of a typical Korean diet on cardiovascular risk factors. METHODS: We conducted a randomized, crossover trial in a free-living setting with a 2-week run-in period, two 4-week intervention phases, and a 2-week washout period between interventions...
July 10, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28694455/asymptomatic-meibomian-gland-dysfunction-and-cardiovascular-disease-risk-factors-in-a-middle-aged-population-in-taiwan-a-cross-sectional-analysis
#17
Alexander Chen, Hung-Ta Chen, Hung-Chi Chen, Yi-Tsun Chen, Yih-Hsiou Hwang, Chi-Chin Sun, Ching-Hsi Hsiao, David Hui-Kang Ma, Wei-Chi Wu, Chi-Chun Lai
Managing cardiovascular disease (CVD) risk factors is the key to prevent CVD. This study aimed to prevent CVD by introducing asymptomatic meibomian gland dysfunction (MGD), a condition associated with various CVD risk factors, as an early indicator for CVD in middle-aged population. Participants with and without asymptomatic MGD underwent standardized questionnaires, physical examinations, and laboratory investigations. One ophthalmologist completed the identification and grading of MGD by using slit-lamp biomicroscopy examination on the eyelid margins, meibomian gland orifices, and meibomian gland secretions...
July 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28691976/distinct-lipoprotein-curves-in-normal-weight-overweight-and-obese-children-and-adolescents
#18
Hagar Interator, Yael Lebenthal, Moshe Hoshen, Inbar Safra, Ran Balicer, Moshe Leshno, Raanan Shamir
OBJECTIVES: Pediatric lipoprotein curves are based on population-based samples. As obesity, may alter lipoprotein levels, cut-offs not adjusted for body mass index (BMI) are potentially inappropriate. We aimed to develop distinct serum lipid curves based on sex and BMI-percentiles for children and adolescents. METHODS: Cross-sectional analysis included all healthy children and adolescents (age range 2-17 years) with available serum lipid concentrations (n = 152,820 of approximately 1...
July 6, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28691419/circulating-pcsk9-over-srebp-2-expression-affects-serum-ldl-and-cholesterol-levels
#19
Asghar Mohammadi, Mohamad Shabani, Faezeh Naseri, Bita Hosseni, Elham Soltanmohammadi, Sadegh Piran, Mohammad Najafi
BACKGROUND: Cholesterol homeostasis is dependent upon sterol regulation element binding protein2 (SREBP-2) regulatory system and plasma proprotein convertase subtilin/kexin type 9 (PCSK9) function. Furthermore, many studies have reported that cellular membrane LDLR level is related to the function of these proteins. OBJECTIVES: The aim of this study was to investigate the association of lipid profile with circulating PCSK9 protein value and SREBP-2 expression level in normal subjects...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28691416/the-relationship-between-major-depressive-disorders-and-glucose-parameters-a-cross-sectional-study-in-chinese-population
#20
You-Fan Peng, Shi-Mao Zhong, Qin Yu-Hua, Xu Hui-Dan, Wei Wu-Jun
BACKGROUND: Depressive symptoms have been linked with insulin resistance in middle-aged and elderly population. A strong relationship between peripheral insulin resistance and glucose homeostasis imbalance has well been established in previous study. The role of serum fructosamine and fasting blood glucose (FBG) for the elevation in glucose homeostasis has been documented in the literature. OBJECTIVES: We examined the association of serum fructosamine , FBG with major depressive disorders (MDD)...
June 27, 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
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