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Urticary

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https://www.readbyqxmd.com/read/29338163/kounis-syndrome-induced-by-oral-intake-of-diclofenac-potassium
#1
Harun Gunes, Feruza Turan Sonmez, Ayhan Saritas, Yasin Koksal
An acute coronary syndrome (ACS) occurring during the course of an allergic reaction is called Kounis syndrome (KS). The second case of KS induced by diclofenac potassium (DP) is presented in this report. A 67-year-old man was brought to our emergency department with the possible diagnosis of anaphylactic shock by the ambulance staff. It emerged that widespread erythema and pruritus developed after taking DP. Then, he lost consciousness. Diffuse urticarial lesions were detected on physical examination at the emergency department...
December 2017: Iranian Journal of Allergy, Asthma, and Immunology
https://www.readbyqxmd.com/read/29329127/cutis-laxa-acquisita-after-urticarial-vasculitis-in-sle-patients
#2
Kimberly B Golisch, Silvija P Gottesman, Patricia Ferrer, Keliegh S Culpepper
Cutis laxa is a rare connective tissue disease involving damage to dermal elastic fibers creating a clinical appearance of loose, sagging skin. The condition can be either acquired or genetic. Autoimmune diseases, neoplasms, infections, and medications have been proposed as the cause of, or in association with, the acquired form. In nearly 50% of cases, erythematous plaques present before the onset of cutis laxa. Separately, urticarial vasculitis and systemic lupus erythematosus have been linked to cutis laxa acquisita...
January 11, 2018: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/29284595/molecular-genetic-investigation-clinical-features-and-response-to-treatment-in-21-patients-with-schnitzler-s-syndrome
#3
Dorota M Rowczenio, Shelly Pathak, Juan I Arostegui, Anna Mensa-Vilaro, Ebun Omoyinmi, Paul Brogan, Dan Lipsker, Thomas Scambler, Roger Owen, Hadija Trojer, Anna Baginska, Julian D Gillmore, Ashutosh D Wechalekar, Thirusha Lane, Rene Williams, Taryn Youngstein, Philip N Hawkins, Sinisa Savic, Helen J Lachmann
To date, the pathogenic mechanisms underlying Schnitzler's syndrome remain obscure, in particular the interplay between the monoclonal protein and increased IL-1beta production, although interest in the contribution of genetic factors has been fuelled by detection of somatic NLRP3 mosaicism in two patients with the variant-type Schnitzler's syndrome. At two specialist UK centres we have identified 21 patients, who fulfilled diagnostic criteria for Schnitzler's syndrome with urticarial rash, fever, arthralgia and bone pain; 47% reported weight loss, 40% fatigue and 21% lymphadenopathy...
December 28, 2017: Blood
https://www.readbyqxmd.com/read/29282190/immunologic-studies-of-progesterone-induced-neutrophilic-urticaria
#4
Papapit Tuchinda, Corinne Erickson, Antonella Tammaro, Miya Okada Paterniti, Sarbjit S Saini, Anthony A Gaspari
A 33-year-old woman presented with recurring pruritic, erythematous papules around the mouth and on the hands, of 1.5 years' duration. These flares typically began several days before her menstrual cycle and persisted for approximately 1 week. Physical examination revealed urticarial plaques on the neck. Due to the nature of the eruption, which corresponded with her menstrual cycle, a diagnosis of autoimmune progesterone urticaria was considered and workup pursued.
2017: Skinmed
https://www.readbyqxmd.com/read/29274313/mitral-ring-extraction-due-to-nickel-allergy
#5
Carlos Dominguez-Massa, Ana M Bel-Minguez, Manuel Perez-Guillen, Alberto Berbel-Bonillo, Fernando Hornero-Sos
The incidence of allergic reactions due to mechanical prosthesis or rings is not well established. We report the case of a 56-year-old male patient who presented a persistent urticarial rash and anaphylactic shock after mitral valve repair surgery. Prick skin tests were positive for nickel. After removing the nucleus from the mitral annulus, the urticarial clinic disappeared.
December 20, 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/29225799/kidney-involvement-in-the-schnitzler-syndrome-a-rare-disease
#6
REVIEW
Carlo Basile, Luigi Rossi, Francesco Casucci, Annalisa Teutonico, Pasquale Libutti, Piero Lisi, Carlo Lomonte, Raffaele Manna
The Schnitzler syndrome (SS) is a rare and underdiagnosed entity that associates a chronic urticarial rash, monoclonal IgM (or sometimes IgG) gammopathy and signs and symptoms of systemic inflammation. During the past 45 years, the SS has evolved from an elusive little-known disorder to the paradigm of a late-onset acquired auto-inflammatory syndrome. Though there is no definite proof of its precise pathogenesis, it should be considered as an acquired disease involving abnormal stimulation of the innate immune system, which can be reversed by the interleukin-1 receptor antagonist anakinra...
December 2017: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29214791/a-case-of-schnitzler-s-syndrome-without-monoclonal-gammopathy-associated-chronic-urticaria-treated-with-anakinra
#7
Min Joo Ahn, Ji Eun Yu, Jiung Jeong, Da Woon Sim, Young Il Koh
Chronic urticaria may often be associated with interleukin (IL)-1-mediated autoinflammatory disease, which should be suspected if systemic inflammation signs are present. Here, we report a case of Schnitzler's syndrome without monoclonal gammopathy treated successfully with the IL-1 receptor antagonist anakinra. A 69-year-old man suffered from a pruritic urticarial rash for 12 years. It became aggravated episodically and was accompanied by high fever, arthralgia, leukocytosis, and an elevated C-reactive protein and erythrocyte sedimentation rate...
January 2018: Yonsei Medical Journal
https://www.readbyqxmd.com/read/29199964/a-case-of-hypocomplementemic-urticarial-vasculitis-syndrome-successfully-treated-with-omalizumab
#8
E Nucera, F Basta, A Buonomo, S Mezzacappa, D P Margiotta, R Antonelli Incalzi, D Schiavino
No abstract text is available yet for this article.
2017: Journal of Investigational Allergology & Clinical Immunology
https://www.readbyqxmd.com/read/29191376/clinical-histological-immunological-presentations-and-outcomes-of-bullous-systemic-lupus-erythematosus-10-new-cases-and-a-literature-review-of-118-cases
#9
Tullia de Risi-Pugliese, Fleur Cohen Aubart, Julien Haroche, Philippe Moguelet, Sabine Grootenboer-Mignot, Alexis Mathian, Saskia Ingen-Housz-Oro, Miguel Hie, Noémie Wendremaire, Françoise Aucouturier, François Lepelletier, Makoto Miyara, Brigitte Bader-Meunier, Philippe Rémy, Nicole Fabien, Camille Francès, Stéphane Barete, Zahir Amoura
BACKGROUND: Bullous systemic lupus erythematosus (BSLE) is a rare blistering condition associated with systemic lupus erythematosus (SLE). PATIENTS AND METHODS: We conducted a multi-center retrospective study and literature review in order to describe the clinical, immunological, and histological presentations and outcomes of BSLE. The skin biopsies were centrally reviewed, and sera obtained during a flare of BSLE were analyzed for identification of circulating anti-basement membrane zone antibodies...
November 4, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29172941/reporting-of-adverse-events-following-immunizations-in-ghana-using-disproportionality-analysis-reporting-ratios
#10
Daniel N A Ankrah, Delese M Darko, George Sabblah, Aukje Mantel-Teeuwisse, Hubert M G Leufkens
BACKGROUND: Timely reporting of safety information post vaccination is pivotal for the success of any vaccination program. Reports of adverse events following immunization (AEFI) of 6 different vaccinations from Ghana were analysed for signals. METHODS: De-identified data from active surveillance for AEFIs after 2009 AH1N1 influenza, yellow fever, meningitis, measles-rubella, pneumococcal-rotavirus and human papilloma virus vaccinations were used. All vaccinations occurred between January 2010 and December 2013...
November 27, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29164681/urticarial-vasculitis-after-meningococcal-serogroup-b-vaccine-in-a-6-year-old-girl
#11
Virginia Velasco-Tamariz, Marta Prieto-Barrios, Fátima Tous-Romero, Sara Isabel Palencia-Pérez, Concepción Postigo-Llorente
The first vaccine that shows significant potential in providing broad coverage against serogroup B meningococcal disease has recently been approved. Because of its newness, potential adverse events need to be reported. Here we report a case of urticarial vasculitis, a rare disease in children, in probable relationship with the novel vaccine.
November 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29129889/-an-adult-case-of-egg-allergy-treated-with-rush-oral-immunotherapy
#12
Mayumi Yamazaki, Atsushi Isozaki, Aki Tanaka, Eriko Ando, Yoichi Nakamura, Kazuyuki Kurihara
A 26-year-old female patient exhibited symptoms associated with egg allergy, which had been present since early childhood. The patient requested the treatment of egg allergy and was admitted to our hospital for rush oral immunotherapy. The threshold was determined by an oral food challenge test, after positive results on a double-blind food challenge test. The patient ingested dry powder of raw egg-white 5 times per day starting with a tenth of the threshold dose (3.0mg), followed by a 1.2-times increase every time...
2017: Arerugī, [Allergy]
https://www.readbyqxmd.com/read/29115092/hypocomplementemic-urticarial-vasculitis-syndrome-with-membranous-nephropathy-case-report
#13
Su Woong Jung, Yun Young Choi, In Seung Choi, Seulki Kim, Kyung Hwan Jeong, Ran Song, Sang Hoon Lee, Hyung In Yang, Seung Jae Hong, Yeon Ah Lee
Urticarial vasculitis is a rare disorder that principally manifests with recurrent urticarial, sometimes hemorrhagic, skin lesions and/or angioedema. Its clinical presentation is not always limited to cutaneous lesions and it can potentially affect other organs, such as the joints, lungs, kidneys, and eyes. Systemic involvement can either be present at the onset of disease or develop over time. In cases with systemic manifestations, urticarial vasculitis is more likely to be associated with a low complement level...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29114186/clinical-utility-of-anti-c1q-antibody-in-primary-and-secondary-vasculitic-conditions
#14
Kabeerdoss Jayakanthan, And Nikhil Gupta, John Mathew, Raheesh Ravindran, Gowri Mahasampth, Debashish Danda
Objective: Anti-C1q antibodies (Anti-C1q Ab) are seen in hypocomplementemic urticarial vasculitis syndrome (HUVS), infection-associated vasculitis such as hepatitis C virus-related vasculitis and in autoimmune diseases such as rheumatoid vasculitis, polyarteritis nodosa, giant cell arteritis, vascular Behcet's disease, and cryoglobulin associated vasculitis. Aim of this study is to evaluate the presence of Anti-C1q Ab in vasculitis and to determine if any difference exists between primary and secondary vasculitis in relation to this antibody...
November 2017: International Journal of Health Sciences
https://www.readbyqxmd.com/read/29111302/-cryopyrin-associated-periodic-syndromes
#15
P Quartier, F Rodrigues, S Georgin-Lavialle
Cryopyrin-associated periodic syndromes (CAPS) are linked to one single gene mutations, however they are associated with 3 syndromes, which are, from the mildest to the most severe phenotype familial cold urticaria, Muckle-Wells syndrome and chronic, infantile, neurologic, cutaneous, articular (CINCA) syndrome also called neonatal-onset multisystem inflammatory disease (NOMID). Autosomic dominant inheritance is present in most cases but in CINCA/NOMID syndrome where neomutations are more common. Mutations in the gene encoding cryopyrin, NLRP3, are associated with deregulation of caspase-1 activity, excessive interleukin-1 production and an autoinflammatory syndrome, which in familial cold urticaria and Muckle-Wells syndrome may be triggered or worsened by exposure to coldness...
October 27, 2017: La Revue de Médecine Interne
https://www.readbyqxmd.com/read/29102490/nonbullous-cutaneous-pemphigoid-a-systematic-review
#16
REVIEW
Aniek Lamberts, Joost M Meijer, Marcel F Jonkman
BACKGROUND: Cutaneous pemphigoid (bullous pemphigoid) is an autoimmune bullous disease that typically presents with tense bullae and severe pruritus. However, bullae may be lacking, a subtype termed nonbullous cutaneous pemphigoid. OBJECTIVE: To summarize the reported characteristics of nonbullous cutaneous pemphigoid. METHODS: The EMBASE and MEDLINE databases were searched using 'nonbullous cutaneous pemphigoid' and various synonyms. Case reports and series describing nonbullous cutaneous pemphigoid were included...
November 1, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29092674/autoantibodies-against-complement-components-in-systemic-lupus-erythematosus-role-in-the-pathogenesis-and-clinical-manifestations
#17
M H Hristova, V S Stoyanova
Many complement structures and a number of additional factors, i.e. autoantibodies, receptors, hormones and cytokines, are implicated in the complex pathogenesis of systemic lupus erythematosus. Genetic defects in the complement as well as functional deficiency due to antibodies against its components lead to different pathological conditions, usually clinically presented. Among them hypocomplementemic urticarial vasculitis, different types of glomerulonephritis as dense deposit disease, IgA nephropathy, atypical haemolytic uremic syndrome and lupus nephritis are very common...
December 2017: Lupus
https://www.readbyqxmd.com/read/29071428/ige-autoantibodies-and-their-association-with-the-disease-activity-and-phenotype-in-bullous-pemphigoid-a-systematic-review
#18
REVIEW
Ariadne Hadjikyriacou Saniklidou, Patrick J Tighe, Lucy C Fairclough, Ian Todd
Bullous pemphigoid (BP) is the most common autoimmune skin disease of blistering character. The underlying pathophysiological mechanism involves an immune attack, usually by IgG class autoantibodies, on the autoantigen BP 180/BPAg2, which is a type XVII collagen (COL17) protein acting as the adhesion molecule between the epidermis and the basement membrane of the dermis. About 40 years ago, following consistent findings of elevated total serum IgE levels in BP patients, it was hypothesized that IgE may be involved in the pathophysiology of BP...
October 25, 2017: Archives of Dermatological Research
https://www.readbyqxmd.com/read/29064205/the-association-between-serum-vitamin-d-levels-and-urticaria-a-meta-analysis-of-observational-studies
#19
Xiaoyan Wang, Xiaorong Li, Yiwei Shen, Xueyan Wang
BACKGROUND: Despite the recent studies revealed Vitamin D may play a role in urticaria, no meta-analysis providing definite conclusions in this field has been reported. METHODS: A systematic search up to 30thJune 2017 was conducted in MEDLINE (via PubMed) and Excerpta Medica database (EMBASE) to identify relevant articles. Search terms included ''vitamin D'' or "25-hydroxyvitamin D" or ''25hydroxy-vitaminD" or "25(OH)D" or "1,25-dihydroxyvitamin D" combined with ''urticaria"...
October 23, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/29058993/neutrophilic-urticarial-dermatosis-and-sweet-like-neutrophilic-dermatosis-under-recognized-neutrophilic-dermatoses-in-lupus-erythematosus
#20
W J Lee, H J Kang, H J Shin, C H Won, S E Chang, J H Choi, M W Lee
Background/Objectives Neutrophilic dermatoses can be associated with autoimmune connective tissue diseases such as systemic lupus erythematosus (SLE). We analyzed clinical and histological features of neutrophilic urticarial dermatosis (NUD) and Sweet-like neutrophilic dermatosis (SLND)-the most recently delineated entities of the neutrophilic dermatoses. Methods We retrieved database medical records of patients with SLE whose skin biopsy demonstrated a neutrophilic-predominant infiltrate of the skin, and included those whose biopsies revealed findings of SLND or NUD...
January 1, 2017: Lupus
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