keyword
MENU ▼
Read by QxMD icon Read
search

salivary neoplasm

keyword
https://www.readbyqxmd.com/read/29755265/pleomorphic-adenoma-of-the-lacrimal-gland-a-review-with-updates-on-malignant-transformation-and-molecular-genetics
#1
REVIEW
William Harrison, Patricia Pittman, Thomas Cummings
Pleomorphic adenoma (benign mixed tumor) is the most common epithelial neoplasm of the lacrimal gland. It is usually a slow growing, well-circumscribed, mass that is identical to its salivary gland counterpart. Patients generally have an excellent prognosis for vision and long-term survival after complete surgical excision. There is a tendency to reoccur, especially if there is an incomplete excision, and rarely, malignant transformation to carcinoma ex pleomorphic adenoma can occur, which has a much poorer prognosis...
January 2018: Saudi Journal of Ophthalmology: Official Journal of the Saudi Ophthalmological Society
https://www.readbyqxmd.com/read/29739635/cystadenoma-of-the-mandible-a-rare-presentation
#2
H Mahmood, C Murphy, V Oktselglou
To our knowledge this is only the second reported case of a cystadenoma that arose in the mandible. These are rare benign epithelial neoplasms of the salivary gland that comprise 0.8%-6.3% of all minor tumours of the salivary gland. Because cystadenoma of the mandible is so rare, there is little evidence or guidance about management, and enucleation remains the recommended treatment. Careful histological diagnosis is important for differentiation from other morphologically similar salivary gland tumours such as a mucoepidermoid carcinoma...
May 5, 2018: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/29738361/intraductal-papillary-mucinous-neoplasms-of-minor-salivary-glands-with-akt1-p-glu17lys-mutation
#3
Abbas Agaimy, Sarina K Mueller, Klaus Bumm, Heinrich Iro, Evgeny A Moskalev, Arndt Hartmann, Robert Stoehr, Florian Haller
The spectrum of low-grade intraductal papillary proliferations of the salivary glands is heterogenous, and reproducible morphologic diagnostic criteria have not yet been established. Recognized types are sialadenoma papilliferum, inverted ductal papilloma, and intraductal papilloma, but some lesions have been possibly included in the morphologic spectrum of cystadenoma or low-grade intraductal carcinomas. We herein present detailed morphologic, immunophenotypic, and genotypic features of 3 minor salivary gland neoplasms affecting 2 men (aged 65 and 71 y) and 1 woman (aged 78 y)...
May 5, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29731569/bibliometric-analysis-of-oral-and-maxillofacial-cytology-related-articles-published-in-a-cytology-journal-from-india
#4
Thorakkal Shamim
Background: There is a paucity of information about the oral and maxillofacial cytology-related articles published in a cytology journal. Journal of Cytology (JOC) is the official publication of Indian Academy of Cytologists. Objective: This study aimed to audit the oral and maxillofacial cytology-related articles published in JOC from 2007 to 2015 over a 9-year period. Materials and Methods: Bibliometric analysis of issues of JOC from 2007 to 2015 was performed using web-based search...
January 2018: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/29728539/immunohistochemical-detection-of-proliferative-marker-ki-67-in-benign-and-malignant-salivary-gland-tumors
#5
Smita Bussari, Sindhu M Ganvir, Manish Sarode, Prabhakar A Jeergal, Anjum Deshmukh, Himanshu Srivastava
Introduction: Salivary gland tumors are the most histologically heterogeneous group of tumors with the greatest diversity of morphologic features among their cells and tissues. The present study was aimed at assessing the validity of Ki-67, a cell proliferation marker, as a prognostic factor in benign and malignant salivary gland tumors and to study whether it is related to age, sex, anatomical site, and size of the lesion in salivary gland tumors. Materials and methods: A retrospective study consisted of benign salivary gland tumors (BSGTs) (n = 15), malignant salivary gland tumors (n = 18), and normal salivary gland parenchyma (n = 15)...
April 1, 2018: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29725854/metastasising-pleomorphic-salivary-adenoma-a-rare-case-report-of-a-massive-untreated-minor-salivary-gland-pleomorphic-adenoma-with-concurrent-ipsilateral-cervical-node-metastases
#6
Melanie Watson, Peter McAllister, Brendan Conn, Morna MacNeill, Thomas P B Handley
Salivary gland tumours constitute approximately 1-5% of all human neoplasms. Pleomorphic adenoma (PA) is the commonest benign neoplasm affecting the parotid gland most often (> 75%), followed by the submandibular gland (13%), then the palate (9%). Metastasising pleomorphic adenoma (MPA) is extremely rare. The effects can be severe and a reported 40% of MPA patients die with disease. This case represents the first known case in English literature of an untreated minor salivary gland PSA of the palate metastasising to an ipsilateral cervical node...
May 3, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29723435/impact-on-clinical-follow-up-of-the-milan-system-for-salivary-gland-cytology-a-comparison-with-a-traditional-diagnostic-classification
#7
Lester J Layfield, Zubair Baloch, Sharon L Hirschowitz, Esther D Rossi
OBJECTIVE: No universally accepted classification exists for salivary gland fine-needle aspiration (FNA). The proposed Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) offers a uniform classification with management recommendations. We compared FNA diagnoses from a prior study with specific diagnoses with corresponding MSRSGC diagnoses. METHODS: One-hundred and sixty-four cases from a prior cytologic study with histologic follow-up were re-reviewed by one of the authors and assigned to one of the MSRSGC categories...
May 3, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29705927/single-nucleotide-polymorphism-rs11614913-associated-with-cc-genotype-in-mir-196a2-is-overrepresented-in-laryngeal-squamous-cell-carcinoma-but-not-salivary-gland-tumors-in-polish-population
#8
Marcin Skalski, Adam Ustaszewski, Katarzyna Jaskiewicz, Katarzyna Kiwerska, Malgorzata Wierzbicka, Hanna Klimza, Reidar Grenman, Maciej Giefing
The miRNA-196a2 has shown significance in the development of various neoplasms, including head and neck squamous cell carcinoma (HNSCC). The oncogenic functionality of this miRNA is mediated via its potential to target annexin A1 mRNA, a tumor suppressor gene involved in inhibition of the NF-κB pathway. Interestingly, recent data indicate a susceptibility for aforementioned neoplasms in patients with the CC genotype vs the CT and TT genotypes of the rs11614913 SNP located within the DNA sequence of the miR-196a2 that results in elevated expression of the gene...
April 29, 2018: Journal of Applied Genetics
https://www.readbyqxmd.com/read/29699873/report-of-a-unique-case-of-myoepithelial-carcinoma-of-left-parotid-gland-with-metachronous-bilateral-cavernous-sinus-metastasis
#9
Rambha Pandey, Rituparna Biswas, Mukurdipi Ray, Prashant P Ramteke, Ekta Dhamija, Anirban Halder
Myoepithelial carcinoma (MC) is a rare, locally aggressive malignant neoplasm of the salivary glands. Only few evidences on its metastatic behavior are available in the literature. We herein present a unique case of MC of left parotid gland which metastasized to bilateral cavernous sinuses. The patient was successfully treated with palliative radiotherapy and chemotherapy.
April 23, 2018: Journal of the Egyptian National Cancer Institute
https://www.readbyqxmd.com/read/29683536/a-retrospective-three-year-study-of-salivary-gland-fine-needle-aspiration-cytology-with-categorisation-using-the-milan-reporting-system
#10
S A Thiryayi, Y X Low, D Shelton, N Narine, D Slater, D N Rana
OBJECTIVE: To assess our practice using the recently developed standardised classification system designated The Milan System for Reporting Salivary Cytopathology (MSRSGC) and to ascertain the rates of malignancy for each category by means of a retrospective study. METHODS: All salivary gland FNA cytology samples received between 1 January 2013 and 31 December 2015 were retrospectively assigned a diagnostic category code from the MSRSGC. Cytology results were correlated with subsequent histology (where available), clinical and radiological follow up...
April 23, 2018: Cytopathology: Official Journal of the British Society for Clinical Cytology
https://www.readbyqxmd.com/read/29672325/primary-mammary-analog-secretory-carcinoma-masc-of-the-vulva-with-etv6-ntrk3-fusion-a-case-report
#11
Jane K Nguyen, Julia A Bridge, Chandrika Joshi, Jesse K McKenney
Mammary analog secretory carcinoma is a primary salivary gland neoplasm with histologic, immunophenotypic, and molecular features identical to those of secretory carcinoma of the breast. Similar neoplasms have now been reported to occur in various nonmammary sites including the parotid gland, submandibular gland, sinuses, lip, skin, thyroid gland, and lung. We report, to our knowledge, the first example of a primary vulvar neoplasm with pathologic features identical to secretory carcinoma of the breast and an ETV6-NTRK3 fusion...
April 19, 2018: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/29669190/analysis-of-histologic-follow-up-and-risk-of-malignancy-for-salivary-gland-neoplasm-of-uncertain-malignant-potential-proposed-by-the-milan-system-for-reporting-salivary-gland-cytopathology
#12
Haiyan Liu, Clarissa Ljungren, Fan Lin, Matthew A Zarka, Longwen Chen
BACKGROUND: The Milan System for Reporting Salivary Gland Cytopathology is a tiered classification scheme that includes 6 diagnostic categories. Neoplasm, which is 1 of the 6 proposed categories, consists of benign neoplasm and neoplasm of uncertain malignant potential (NUMP). NUMP is reserved for a salivary gland neoplasm without clear distinction between benign and malignant. The objective of this study was to assess the risk of malignancy (ROM) of NUMP. METHODS: A retrospective analysis was conducted on 656 salivary gland fine-needle aspiration specimens from 2010 to 2016...
April 18, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/29649019/nut-carcinoma-of-the-salivary-glands-clinicopathologic-and-molecular-analysis-of-3-cases-and-a-survey-of-nut-expression-in-salivary-gland-carcinomas
#13
Abbas Agaimy, Isabel Fonseca, Carmo Martins, Khin Thway, Ryan Barrette, Kevin J Harrington, Arndt Hartmann, Christopher A French, Cyril Fisher
NUT carcinoma (NC) represents a rare subset of highly aggressive poorly differentiated carcinomas characterized by rearrangement of the NUT (aka NUTM1, nuclear protein in testis) gene, most commonly fused to BRD4. Originally described as a mediastinal/thymic malignancy, NC has been reported at a variety of anatomic regions including the upper and lower aerodigestive tract. To date, only 7 NC cases of probable salivary gland origin have been reported. We herein describe 3 new cases (all affecting the parotid gland) in 2 women (39- and 55-y old) and 1 man (35-y old)...
April 11, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29622119/routine-and-advanced-ultrasound-of-major-salivary-glands
#14
REVIEW
Kunwar Suryaveer Singh Bhatia, Yuk-Ling Dai
Ultrasound is the preferred initial imaging modality in Europe and Asia for assessing the major salivary glands. In experienced hands, it is sensitive for a range of salivary pathologies, often diagnostic, and also a safe, cost-effective gatekeeper for further investigations as well as image-guided diagnostic biopsies and aspirations. This article reviews the scanning technique and normal sonographic anatomy of major salivary glands and overviews typical sonographic appearances of salivary pathologies, including infective and inflammatory conditions, sialolithiasis, and neoplasms...
May 2018: Neuroimaging Clinics of North America
https://www.readbyqxmd.com/read/29615296/reexamining-post-transplant-lymphoproliferative-disorders-newly-recognized-and-enigmatic-types
#15
REVIEW
Nadine Aguilera, Alejandro A Gru
Post-transplant lymphoproliferative disorders (PTLD) are a known risk for both solid organ transplant and stem cell transplant recipients. Overall transplant recipients have a six fold increase in risk for developing any kind of non-Hodgkin lymphoma and PTLDs occur in up to 10% of SOT recipients. Several new entities have been accepted or renamed in the 2018 update of the WHO classification of tumors of hematopoietic and lymphoid neoplasms, including florid follicular hyperplasia and extranodal marginal zone lymphomas of mucosa-associated lymphoid tissue (MALT-lymphoma) (excluding common locations such as stomach and salivary gland)...
March 3, 2018: Seminars in Diagnostic Pathology
https://www.readbyqxmd.com/read/29594833/palatal-polymorphous-adenocarcinoma-with-high-grade-transformation-a-case-report-and-literature-review
#16
Kentaro Kikuchi, Toshitaka Nagao, Fumio Ide, Shota Takizawa, Hideaki Sakashita, Ichiro Tsujino, Tie-Jun Li, Kaoru Kusama
Polymorphous adenocarcinoma (PAC) is the second most common intraoral malignant neoplasm of the minor salivary glands. However, it is very rare for PAC to show high-grade transformation (HGT) and to our knowledge, the English literature only seven reported cases. HGT tends to be observed when PAC recurs, and it is extremely rare to be seen at initial presentation. Here we report a 43-year-old Japanese male patient with PAC of the right palate showing HGT at initial presentation. Histopathologically, the tumor was characterized by a prominent solid and papillary-cystic growth pattern, with nuclear atypia and necrosis in area of HGT...
March 29, 2018: Head and Neck Pathology
https://www.readbyqxmd.com/read/29579353/northern-italy-in-the-american-south-assessing-interobserver-reliability-within-the-milan-system-for-reporting-salivary-gland-cytopathology
#17
Johnathan M Hollyfield, Siobhan M O'Connor, Susan J Maygarden, Kevin G Greene, Lori R Scanga, Sherry Tang, Leslie G Dodd, Sara E Wobker
BACKGROUND: The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has been proposed to standardize salivary gland fine-needle aspiration (FNA) diagnoses. This study assessed salivary gland FNA results and risk of malignancy (ROM) rates at the University of North Carolina as well as the interobserver reliability (IOR) of the atypia of undetermined significance (AUS) and salivary gland neoplasm of uncertain malignant potential (SUMP) categories. METHODS: The electronic medical record was searched for FNA cases from 2010 to 2017 with subsequent surgical resections...
March 26, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/29577637/patient-s-perspective-on-long-term-complications-after-superficial-parotidectomy-for-benign-lesions-prospective-analysis-of-a-two-year-follow-up
#18
P Wolber, G F Volk, L Horstmann, M Finkensieper, S Shabli, C Wittekindt, J P Klussmann, O Guntinas-Lichius, D Beutner, M Grosheva
OBJECTIVE: Evaluation of patient's perspective on long-term complications after superficial parotidectomy for benign lesions. DESIGN: A prospective nonrandomized controlled multicenter study. SETTING: Three university-based tertiary referral centers (Departments of Otorhinolaryngology of Cologne, Jena and Giessen; all in Germany). PARTICIPANTS: 130 adult patients, who underwent a primary superficial parotidectomy for benign tumors of the parotid gland, were consecutively included from 09/2010 to 05/2012...
March 26, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29577164/assessment-of-ctnnb1-gene-mutations-and-%C3%AE-catenin-immunoexpression-in-salivary-gland-pleomorphic-adenomas-and-adenoid-cystic-carcinomas
#19
Roberta Barroso Cavalcante, Cassiano Francisco Weege Nonaka, Hellen Bandeira de Pontes Santos, Silvia Helena Barem Rabenhorst, Leão Pereira Pinto, Lélia Batista de Souza
β-Catenin exerts multiple functions in several neoplasms, playing a major role in cell signaling and tumor progression. This study analyzed possible CTNNB1 mutations in salivary gland pleomorphic adenomas (PAs) and adenoid cystic carcinomas (ACCs), and determined possible differences in β-catenin immunoexpression in relation to these mutations, as well as histopathological aspects of these tumors. Twenty-four PAs (15 cell-rich and 9 cell-poor tumors) and 24 ACCs (10 tubular, 8 cribriform, and 6 solid tumors) were selected for the analysis of β-catenin distribution and cellular localization...
March 26, 2018: Virchows Archiv: An International Journal of Pathology
https://www.readbyqxmd.com/read/29570128/small-subset-of-adenoid-cystic-carcinoma-of-the-skin-is-associated-with-alterations-of-the-mybl1-gene-similar-to-their-extracutaneous-counterparts
#20
Liubov Kyrpychova, Tomas Vanecek, Petr Grossmann, Petr Martinek, Petr Steiner, Ladislav Hadravsky, Irena E Belousova, Ksenya V Shelekhova, Marian Svajdler, Pavol Dubinsky, Michal Michal, Dmitry V Kazakov
Adenoid cystic carcinoma (ACC) of the skin is a rare malignant neoplasm histologically identical to homonymous tumors in other organs. Cutaneous ACC has been found to harbor MYB gene activations, either through MYB chromosomal abnormalities or by generation of the MYB-NFIB fusion. In salivary gland ACC, in addition to the MYB gene, alterations in MYBL1, the gene closely related to MYB, have been reported. We studied 10 cases of cutaneous ACC (6 women, 4 men; and age range 51-83 years) for alterations in the MYB, NFIB, and MYBL1 genes, using FISH and PCR...
March 21, 2018: American Journal of Dermatopathology
keyword
keyword
44221
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"