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https://www.readbyqxmd.com/read/27862720/antitumor-activity-of-opiorphin-sialorphin-and-their-conjugates-with-a-peptide-klaklakklaklak
#1
Elżbieta Kamysz, Ryszard Smolarczyk, Tomasz Cichoń, Magdalena Jarosz-Biej, Emilia Sikorska, Małgorzata Sobocińska, Maciej Jaśkiewicz, Wojciech Kamysz
This is the study on the effect of opiorphin, sialorphin and their analogs on antitumor activity. We demonstrated that conjugation of opiorphin and sialorphin with a proapoptotic, antimicrobial peptide klak (klaklakklaklak) led to compounds (opio-klak and sialo-klak) that were cytotoxic against cancer cells (LN18, PC3, A549, HCT116 and B10-F16) in the MTT test. The conjugated analogs were designed to increase the effectiveness of the peptide. The opio-klak derivative was the most effective in the in vitro assays and led to a decrease in viability of cancer cells over time as compared with that of untreated controls...
November 9, 2016: Journal of Peptide Science: An Official Publication of the European Peptide Society
https://www.readbyqxmd.com/read/27859220/farmland-biodiversity-and-agricultural-management-on-237-farms-in-13-european-and-two-african-regions
#2
Gisela Lüscher, Youssef Ammari, Aljona Andriets, Siyka Angelova, Michaela Arndorfer, Debra Bailey, Katalin Balázs, Marion Bogers, Robert G H Bunce, Jean-Philippe Choisis, Peter Dennis, Mario Díaz, Tetyana Dyman, Sebastian Eiter, Wendy Fjellstad, Mariecia Fraser, Jürgen K Friedel, Salah Garchi, Ilse R Geijzendorffer, Tiziano Gomiero, Guillermo González-Bornay, Yana Guteva, Felix Herzog, Philippe Jeanneret, Rob H G Jongman, Max Kainz, Norman Kwikiriza, María Lourdes López Díaz, Gerardo Moreno, Pip Nicholas-Davies, Charles Nkwiine, Julius Opio, Maurizio G Paoletti, László Podmaniczky, Philippe Pointereau, Fernando Pulido, Jean-Pierre Sarthou, Manuel K Schneider, Tahar Sghaier, Norman Siebrecht, Siyka Stoyanova, Sebastian Wolfrum, Sergiy Yashchenko, Harald Albrecht, András Báldi, Márta Belényesi, Jacinto Benhadi-Marin, Theo Blick, Serge Buholzer, Csaba Centeri, Norma Choisis, Gérard Cuendet, Hendrika J De Lange, Sylvain Déjean, Christo Deltshev, Darío J Díaz Cosín, Wenche Dramstad, Zoltán Elek, Gunnar Engan, Konstantin Evtushenko, Eszter Falusi, Oliver-D Finch, Thomas Frank, Federico Gavinelli, David Genoud, Phillipa K Gillingham, Viktor Grónás, Mónica Gutiérrez, Werner Häusler, Xaver Heer, Thomas Hübner, Marco Isaia, Gergely Jerkovich, Juan B Jesus, Esezah Kakudidi, Eszter Kelemen, Nóra Koncz, Eszter Kovacs, Anikó Kovács-Hostyánszki, Luisa Last, Toshko Ljubomirov, Klaus Mandery, Josef Mayr, Atle Mjelde, Christoph Muster, Juri Nascimbene, Johann Neumayer, Frode Ødegaard, Francisco Javier Ortiz Sánchez, Marie-Louise Oschatz, Susanne Papaja-Hülsbergen, Mauro Paschetta, Mark Pavett, Céline Pelosi, Károly Penksza, Reidun Pommeresche, Victor Popov, Volodymyr Radchenko, Nina Richner, Susanne Riedel, John Scullion, Daniele Sommaggio, Ottó Szalkovszki, Erich Szerencsits, Dolores Trigo, Jim Vale, Ruud van Kats, Angel Vasilev, Andrew E Whittington, Jerylee Wilkes-Allemann, Tommaso Zanetti
Farmland is a major land cover type in Europe and Africa and provides habitat for numerous species. The severe decline in farmland biodiversity of the last decades has been attributed to changes in farming practices, and organic and low-input farming are assumed to mitigate detrimental effects of agricultural intensification on biodiversity. Since the farm enterprise is the primary unit of agricultural decision making, management-related effects at the field scale need to be assessed at the farm level. Therefore, in this study, data were collected on habitat characteristics, vascular plant, earthworm, spider, and bee communities and on the corresponding agricultural management in 237 farms in 13 European and two African regions...
June 2016: Ecology
https://www.readbyqxmd.com/read/27761581/evaluation-of-an-overlapping-pubic-and-ischiatic-osteotomy-for-the-improvement-of-acetabular-ventroversion-in-dogs-an-ex-vivo-study
#3
Julie A Gervais, James K Roush, David S Biller
OBJECTIVES: To assess the potential of a new single-session surgical procedure, the overlapping pubic and ischiatic osteotomy (OPIO) for modification of bilateral hip conformation. We hypothesized that OPIO would be simple to perform with currently available surgical equipment, through a single surgical approach, with minimal potential morbidity, and that it would allow adequate simultaneous bilateral improvement of coxofemoral joint conformation in patients at risk of canine hip dysplasia...
October 20, 2016: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/27518562/astrocytic-insulin-signaling-couples-brain-glucose-uptake-with-nutrient-availability
#4
Cristina García-Cáceres, Carmelo Quarta, Luis Varela, Yuanqing Gao, Tim Gruber, Beata Legutko, Martin Jastroch, Pia Johansson, Jovica Ninkovic, Chun-Xia Yi, Ophelia Le Thuc, Klara Szigeti-Buck, Weikang Cai, Carola W Meyer, Paul T Pfluger, Ana M Fernandez, Serge Luquet, Stephen C Woods, Ignacio Torres-Alemán, C Ronald Kahn, Magdalena Götz, Tamas L Horvath, Matthias H Tschöp
We report that astrocytic insulin signaling co-regulates hypothalamic glucose sensing and systemic glucose metabolism. Postnatal ablation of insulin receptors (IRs) in glial fibrillary acidic protein (GFAP)-expressing cells affects hypothalamic astrocyte morphology, mitochondrial function, and circuit connectivity. Accordingly, astrocytic IR ablation reduces glucose-induced activation of hypothalamic pro-opio-melanocortin (POMC) neurons and impairs physiological responses to changes in glucose availability...
August 11, 2016: Cell
https://www.readbyqxmd.com/read/27470028/estimates-of-global-regional-and-national-incidence-prevalence-and-mortality-of-hiv-1980-2015-the-global-burden-of-disease-study-2015
#5
Haidong Wang, Tim M Wolock, Austin Carter, Grant Nguyen, Hmwe Hmwe Kyu, Emmanuela Gakidou, Simon I Hay, Edward J Mills, Adam Trickey, William Msemburi, Matthew M Coates, Meghan D Mooney, Maya S Fraser, Amber Sligar, Joshua Salomon, Heidi J Larson, Joseph Friedman, Amanuel Alemu Abajobir, Kalkidan Hassen Abate, Kaja M Abbas, Mohamed Magdy Abd El Razek, Foad Abd-Allah, Abdishakur M Abdulle, Semaw Ferede Abera, Ibrahim Abubakar, Laith J Abu-Raddad, Niveen M E Abu-Rmeileh, Gebre Yitayih Abyu, Akindele Olupelumi Adebiyi, Isaac Akinkunmi Adedeji, Ademola Lukman Adelekan, Koranteng Adofo, Arsène Kouablan Adou, Oluremi N Ajala, Tomi F Akinyemiju, Nadia Akseer, Faris Hasan Al Lami, Ziyad Al-Aly, Khurshid Alam, Noore K M Alam, Deena Alasfoor, Saleh Fahed S Aldhahri, Robert William Aldridge, Miguel Angel Alegretti, Alicia V Aleman, Zewdie Aderaw Alemu, Rafael Alfonso-Cristancho, Raghib Ali, Ala'a Alkerwi, François Alla, Rajaa Mohammad, Salem Al-Raddadi, Ubai Alsharif, Elena Alvarez, Nelson Alvis-Guzman, Azmeraw T Amare, Alemayehu Amberbir, Adeladza Kofi Amegah, Walid Ammar, Stephen Marc Amrock, Carl Abelardo T Antonio, Palwasha Anwari, Johan Ärnlöv, Al Artaman, Hamid Asayesh, Rana Jawad Asghar, Reza Assadi, Suleman Atique, Lydia S Atkins, Euripide Frinel G Arthur Avokpaho, Ashish Awasthi, Beatriz Paulina Ayala Quintanilla, Umar Bacha, Alaa Badawi, Aleksandra Barac, Till Bärnighausen, Arindam Basu, Tigist Assefa Bayou, Yibeltal Tebekaw Bayou, Shahrzad Bazargan-Hejazi, Justin Beardsley, Neeraj Bedi, Derrick A Bennett, Isabela M Bensenor, Balem Demtsu Betsu, Addisu Shunu Beyene, Eesh Bhatia, Zulfiqar A Bhutta, Sibhatu Biadgilign, Boris Bikbov, Sait Mentes Birlik, Donal Bisanzio, Michael Brainin, Alexandra Brazinova, Nicholas J K Breitborde, Alexandria Brown, Michael Burch, Zahid A Butt, Julio Cesar Campuzano, Rosario Cárdenas, Juan Jesus Carrero, Carlos A Castañeda-Orjuela, Jacqueline Castillo Rivas, Ferrán Catalá-López, Hsing-Yi Chang, Jung-Chen Chang, Laxmikant Chavan, Wanqing Chen, Peggy Pei-Chia Chiang, Mirriam Chibalabala, Vesper Hichilombwe Chisumpa, Jee-Young Jasmine Choi, Devasahayam Jesudas Christopher, Liliana G Ciobanu, Cyrus Cooper, Tukur Dahiru, Solomon Abreha Damtew, Lalit Dandona, Rakhi Dandona, José das Neves, Pieter de Jager, Diego De Leo, Louisa Degenhardt, Robert P Dellavalle, Kebede Deribe, Amare Deribew, Don C Des Jarlais, Samath D Dharmaratne, Eric L Ding, Pratik Pinal Doshi, Tim R Driscoll, Manisha Dubey, Yousef Mohamed Elshrek, Iqbal Elyazar, Aman Yesuf Endries, Sergey Petrovich Ermakov, Babak Eshrati, Alireza Esteghamati, Imad D A Faghmous, Carla Sofia E Sa Farinha, Andre Faro, Maryam S Farvid, Farshad Farzadfar, Seyed-Mohammad Fereshtehnejad, Joao C Fernandes, Florian Fischer, Joseph Robert Ander Fitchett, Nataliya Foigt, Nancy Fullman, Thomas Fürst, Fortuné Gbètoho Gankpé, Teshome Gebre, Amanuel Tesfay Gebremedhin, Alemseged Aregay Gebru, Johanna M Geleijnse, Bradford D Gessner, Peter W Gething, Tsegaye Tewelde Ghiwot, Maurice Giroud, Melkamu Dedefo Gishu, Elizabeth Glaser, Shifalika Goenka, Amador Goodridge, Sameer Vali Gopalani, Atsushi Goto, Harish Chander Gugnani, Mark D C Guimaraes, Rahul Gupta, Rajeev Gupta, Vipin Gupta, Juanita Haagsma, Nima Hafezi-Nejad, Holly Hagan, Gessessew Bugssa Hailu, Randah Ribhi Hamadeh, Samer Hamidi, Mouhanad Hammami, Graeme J Hankey, Yuantao Hao, Hilda L Harb, Sivadasanpillai Harikrishnan, Josep Maria Haro, Kimani M Harun, Rasmus Havmoeller, Mohammad T Hedayati, Ileana Beatriz Heredia-Pi, Hans W Hoek, Masako Horino, Nobuyuki Horita, H Dean Hosgood, Damian G Hoy, Mohamed Hsairi, Guoqing Hu, Hsiang Huang, John J Huang, Kim Moesgaard Iburg, Bulat T Idrisov, Kaire Innos, Veena J Iyer, Kathryn H Jacobsen, Nader Jahanmehr, Mihajlo B Jakovljevic, Mehdi Javanbakht, Achala Upendra Jayatilleke, Panniyammakal Jeemon, Vivekanand Jha, Guohong Jiang, Ying Jiang, Tariku Jibat, Jost B Jonas, Zubair Kabir, Ritul Kamal, Haidong Kan, André Karch, Corine Kakizi Karema, Dimitris Karletsos, Amir Kasaeian, Anil Kaul, Norito Kawakami, Jeanne Françoise Kayibanda, Peter Njenga Keiyoro, Andrew Haddon Kemp, Andre Pascal Kengne, Chandrasekharan Nair Kesavachandran, Yousef Saleh Khader, Ibrahim Khalil, Abdur Rahman Khan, Ejaz Ahmad Khan, Young-Ho Khang, Jagdish Khubchandani, Yun Jin Kim, Yohannes Kinfu, Miia Kivipelto, Yoshihiro Kokubo, Soewarta Kosen, Parvaiz A Koul, Ai Koyanagi, Barthelemy Kuate Defo, Burcu Kucuk Bicer, Veena S Kulkarni, G Anil Kumar, Dharmesh Kumar Lal, Hilton Lam, Jennifer O Lam, Sinead M Langan, Van C Lansingh, Anders Larsson, James Leigh, Ricky Leung, Yongmei Li, Stephen S Lim, Steven E Lipshultz, Shiwei Liu, Belinda K Lloyd, Giancarlo Logroscino, Paulo A Lotufo, Raimundas Lunevicius, Hassan Magdy Abd El Razek, Mahdi Mahdavi, Marek Majdan, Azeem Majeed, Carla Makhlouf, Reza Malekzadeh, Chabila C Mapoma, Wagner Marcenes, Jose Martinez-Raga, Melvin Barrientos Marzan, Felix Masiye, Amanda J Mason-Jones, Bongani M Mayosi, Martin McKee, Peter A Meaney, Man Mohan Mehndiratta, Alemayehu B Mekonnen, Yohannes Adama Melaku, Peter Memiah, Ziad A Memish, Walter Mendoza, Atte Meretoja, Tuomo J Meretoja, Francis Apolinary Mhimbira, Ted R Miller, Joseph Mikesell, Mojde Mirarefin, Karzan Abdulmuhsin Mohammad, Shafiu Mohammed, Ali H Mokdad, Lorenzo Monasta, Maziar Moradi-Lakeh, Rintaro Mori, Ulrich O Mueller, Brighton Murimira, Gudlavalleti Venkata Satyanarayana Murthy, Aliya Naheed, Luigi Naldi, Vinay Nangia, Denis Nash, Haseeb Nawaz, Chakib Nejjari, Frida Namnyak Ngalesoni, Jean de Dieu Ngirabega, Quyen Le Nguyen, Muhammad Imran Nisar, Ole F Norheim, Rosana E Norman, Luke Nyakarahuka, Felix Akpojene Ogbo, In-Hwan Oh, Foluke Adetola Ojelabi, Bolajoko Olubukunola Olusanya, Jacob Olusegun Olusanya, John Nelson Opio, Eyal Oren, Erika Ota, Mahesh Anand Padukudru, Hye-Youn Park, Jae-Hyun Park, Snehal T Patil, Scott B Patten, Vinod K Paul, Katherine Pearson, Emmanuel Kwame Peprah, Claudia C Pereira, Norberto Perico, Konrad Pesudovs, Max Petzold, Michael Robert Phillips, Julian David Pillay, Dietrich Plass, Suzanne Polinder, Farshad Pourmalek, David M Prokop, Mostafa Qorbani, Anwar Rafay, Kazem Rahimi, Vafa Rahimi-Movaghar, Mahfuzar Rahman, Mohammad Hifz Ur Rahman, Sajjad Ur Rahman, Rajesh Kumar Rai, Sasa Rajsic, Usha Ram, Saleem M Rana, Paturi Vishnupriya Rao, Giuseppe Remuzzi, David Rojas-Rueda, Luca Ronfani, Gholamreza Roshandel, Ambuj Roy, George Mugambage Ruhago, Mohammad Yahya Saeedi, Rajesh Sagar, Muhammad Muhammad Saleh, Juan R Sanabria, Itamar S Santos, Rodrigo Sarmiento-Suarez, Benn Sartorius, Monika Sawhney, Aletta E Schutte, David C Schwebel, Soraya Seedat, Sadaf G Sepanlou, Edson E Servan-Mori, Masood Ali Shaikh, Rajesh Sharma, Jun She, Sara Sheikhbahaei, Jiabin Shen, Kenji Shibuya, Hwashin Hyun Shin, Inga Dora Sigfusdottir, Naris Silpakit, Diego Augusto Santos Silva, Dayane Gabriele Alves Silveira, Edgar P Simard, Shireen Sindi, Jasvinder A Singh, Om Prakash Singh, Prashant Kumar Singh, Vegard Skirbekk, Karen Sliwa, Samir Soneji, Reed J D Sorensen, Joan B Soriano, David O Soti, Chandrashekhar T Sreeramareddy, Vasiliki Stathopoulou, Nicholas Steel, Bruno F Sunguya, Soumya Swaminathan, Bryan L Sykes, Rafael Tabarés-Seisdedos, Roberto Tchio Talongwa, Mohammad Tavakkoli, Bineyam Taye, Bemnet Amare Tedla, Tesfaye Tekle, Girma Temam Shifa, Awoke Misganaw Temesgen, Abdullah Sulieman Terkawi, Fisaha Haile Tesfay, Gizachew Assefa Tessema, Kiran Thapa, Alan J Thomson, Andrew L Thorne-Lyman, Ruoyan Tobe-Gai, Roman Topor-Madry, Jeffrey Allen Towbin, Bach Xuan Tran, Zacharie Tsala Dimbuene, Nikolaos Tsilimparis, Abera Kenay Tura, Kingsley Nnanna Ukwaja, Chigozie Jesse Uneke, Olalekan A Uthman, N Venketasubramanian, Sergey K Vladimirov, Vasiliy Victorovich Vlassov, Stein Emil Vollset, Linhong Wang, Elisabete Weiderpass, Robert G Weintraub, Andrea Werdecker, Ronny Westerman, Tissa Wijeratne, James D Wilkinson, Charles Shey Wiysonge, Charles D A Wolfe, Sungho Won, John Q Wong, Gelin Xu, Ajit Kumar Yadav, Bereket Yakob, Ayalnesh Zemene Yalew, Yuichiro Yano, Mehdi Yaseri, Henock Gebremedhin Yebyo, Paul Yip, Naohiro Yonemoto, Seok-Jun Yoon, Mustafa Z Younis, Chuanhua Yu, Shicheng Yu, Zoubida Zaidi, Maysaa El Sayed Zaki, Hajo Zeeb, Hao Zhang, Yong Zhao, Sanjay Zodpey, Leo Zoeckler, Liesl Joanna Zuhlke, Alan D Lopez, Christopher J L Murray
BACKGROUND: Timely assessment of the burden of HIV/AIDS is essential for policy setting and programme evaluation. In this report from the Global Burden of Disease Study 2015 (GBD 2015), we provide national estimates of levels and trends of HIV/AIDS incidence, prevalence, coverage of antiretroviral therapy (ART), and mortality for 195 countries and territories from 1980 to 2015. METHODS: For countries without high-quality vital registration data, we estimated prevalence and incidence with data from antenatal care clinics and population-based seroprevalence surveys, and with assumptions by age and sex on initial CD4 distribution at infection, CD4 progression rates (probability of progression from higher to lower CD4 cell-count category), on and off antiretroviral therapy (ART) mortality, and mortality from all other causes...
August 2016: Lancet HIV
https://www.readbyqxmd.com/read/27411834/effect-of-maternal-helicobacter-pylori-infection-on-birth-weight-in-an-urban-community-in-uganda
#6
Ronald Wanyama, Mike N Kagawa, Kenneth C Opio, Rhona K Baingana
BACKGROUND: Helicobacter pylori, a widespread infection particularly in developing countries has been associated with many adverse effects during pregnancy including hyperemesis gravidarum, neural tube defects in newborns, intrauterine fetal growth restriction and miscarriage. We sought to document the effects of H. pylori infection on birth weight in a low-income setting in Kampala, Uganda. METHODS: This was a prospective cohort study conducted in Kampala between May 2012 and May 2013...
2016: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/27410234/modeling-the-impact-of-uganda-s-safe-male-circumcision-program-implications-for-age-and-regional-targeting
#7
Katharine Kripke, Andrea Vazzano, William Kirungi, Joshua Musinguzi, Alex Opio, Rhobbinah Ssempebwa, Susan Nakawunde, Sheila Kyobutungi, Juliet N Akao, Fred Magala, George Mwidu, Delivette Castor, Emmanuel Njeuhmeli
BACKGROUND: Uganda aims to provide safe male circumcision (SMC) to 80% of men ages 15-49 by 2016. To date, only 2 million men have received SMC of the 4.2 million men required. In response to age and regional trends in SMC uptake, the country sought to re-examine its targets with respect to age and subnational region, to assess the program's progress, and to refine the implementation approach. METHODS AND FINDINGS: The Decision Makers' Program Planning Tool, Version 2...
2016: PloS One
https://www.readbyqxmd.com/read/27350934/the-burden-of-tetanus-in-uganda
#8
Barbara Nanteza, Moses Galukande, Jane Aceng, Joshua Musinguzi, Alex Opio, Anthony K Mbonye, Eddie Mukooyo, Prosper Behumize, Fredrick Makumbi
BACKGROUND: The successful scale-up of safe male circumcision (SMC) in Uganda has been hinged on client's safety and quality of services. However, after the recent three tetanus deaths after circumcision a review of all tetanus cases in one of the hospitals where the cases occurred was initiated. This was to ascertain the potential for an association between tetanus infection and circumcision. Routinely collected national data were also reviewed to determine the burden of tetanus in Uganda and contextualize these incidents...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27185416/reducing-emissions-from-agriculture-to-meet-the-2%C3%A2-%C3%A2-c-target
#9
Eva Wollenberg, Meryl Richards, Pete Smith, Petr Havlík, Michael Obersteiner, Francesco N Tubiello, Martin Herold, Pierre Gerber, Sarah Carter, Andrew Reisinger, Detlef P van Vuuren, Amy Dickie, Henry Neufeldt, Björn O Sander, Reiner Wassmann, Rolf Sommer, James E Amonette, Alessandra Falcucci, Mario Herrero, Carolyn Opio, Rosa Maria Roman-Cuesta, Elke Stehfest, Henk Westhoek, Ivan Ortiz-Monasterio, Tek Sapkota, Mariana C Rufino, Philip K Thornton, Louis Verchot, Paul C West, Jean-François Soussana, Tobias Baedeker, Marc Sadler, Sonja Vermeulen, Bruce M Campbell
More than 100 countries pledged to reduce agricultural greenhouse gas (GHG) emissions in the 2015 Paris Agreement of the United Nations Framework Convention on Climate Change. Yet technical information about how much mitigation is needed in the sector vs. how much is feasible remains poor. We identify a preliminary global target for reducing emissions from agriculture of ~1 GtCO2 e yr(-1) by 2030 to limit warming in 2100 to 2 °C above pre-industrial levels. Yet plausible agricultural development pathways with mitigation cobenefits deliver only 21-40% of needed mitigation...
December 2016: Global Change Biology
https://www.readbyqxmd.com/read/26777607/the-alertness-gait-and-mortality-of-severely-ill-patients-at-two-months-after-admission-to-a-resource-poor-sub-saharan-hospital-why-is-post-discharge-surveillance-not-routine-everywhere
#10
Barbara Nabayigga, John Kellett, Martin Otyek Opio
BACKGROUND: Mortality, the first level of the first tier of the Outcomes Measures Hierarchy used to assess the value of health care, is the only hospital outcome usually measured. Gait and alertness after discharge are important to patients; they capture much of the second level of the first tier of the hierarchy, and are required to more fully assess the benefits, value and quality of care. AIM: To assess the alertness, gait and mortality of severely ill patients at two months after admission to a resource poor sub-Saharan hospital...
March 2016: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/26762158/60-years-of-pomc-from-the-prohormone-theory-to-pro-opiomelanocortin-and-to-proprotein-convertases-pcsk1-to-pcsk9
#11
REVIEW
Michel Chrétien, Majambu Mbikay
Pro-opiomelanocortin (POMC), is a polyprotein expressed in the pituitary and the brain where it is proteolytically processed into peptide hormones and neuropeptides with distinct biological activities. It is the prototype of multipotent prohormones. The prohormone theory was first suggested in 1967 when Chrétien and Li discovered γ-lipotropin and observed that (i) it was part of β-lipotropin (β-LPH), a larger polypeptide characterized 2 years earlier and (ii) its C-terminus was β-melanocyte-stimulating hormone (β-MSH)...
May 2016: Journal of Molecular Endocrinology
https://www.readbyqxmd.com/read/26680237/the-mortality-of-acutely-ill-medical-patients-for-up-to-60days-after-admission-to-a-resource-poor-hospital-in-sub-saharan-africa-compared-with-patients-of-similar-illness-severity-admitted-to-a-danish-regional-teaching-hospital-an-exploratory-observational
#12
COMPARATIVE STUDY
Barbara Nabayigga, John Kellett, Mikkel Brabrand, Martin Otyek Opio
BACKGROUND: The outcomes of patients with the same severity of illness in the developed and developing countries have not been compared. Illness severity can now be measured anywhere by the National Early Warning Score (NEWS). METHODS: An exploratory observational study that compared the 7, 30 and 60 days mortality of 195 Ugandan and 588 Danish acutely ill medical patients that had a NEWS >6 at the time of their admission to the hospital. The association of vital sign changes, alertness and mobility at admission on subsequent outcome was explored...
January 2016: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/26424713/sexually-transmitted-infections-associated-with-alcohol-use-and-hiv-infection-among-men-who-have-sex-with-men-in-kampala-uganda
#13
Evelyn J Kim, Wolfgang Hladik, Joseph Barker, George Lubwama, Samuel Sendagala, John M Ssenkusu, Alex Opio, David Serwadda
OBJECTIVES: Few studies have been conducted in Africa to assess prevalence of sexually transmitted infections (STIs) and risk factors among men who have sex with men (MSM). We report findings from the first behavioural survey to include STI testing among MSM in Kampala, Uganda. METHODS: Respondent-driven sampling (RDS) was used to recruit MSM for a biobehavioural survey. Eligible participants were men who reported anal sex with another man in the previous 3 months, were 18 years or older, and resided in Kampala...
May 2016: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/26364544/global-regional-and-national-comparative-risk-assessment-of-79-behavioural-environmental-and-occupational-and-metabolic-risks-or-clusters-of-risks-in-188-countries-1990-2013-a-systematic-analysis-for-the-global-burden-of-disease-study-2013
#14
COMPARATIVE STUDY
Mohammad H Forouzanfar, Lily Alexander, H Ross Anderson, Victoria F Bachman, Stan Biryukov, Michael Brauer, Richard Burnett, Daniel Casey, Matthew M Coates, Aaron Cohen, Kristen Delwiche, Kara Estep, Joseph J Frostad, K C Astha, Hmwe H Kyu, Maziar Moradi-Lakeh, Marie Ng, Erica Leigh Slepak, Bernadette A Thomas, Joseph Wagner, Gunn Marit Aasvang, Cristiana Abbafati, Ayse Abbasoglu Ozgoren, Foad Abd-Allah, Semaw F Abera, Victor Aboyans, Biju Abraham, Jerry Puthenpurakal Abraham, Ibrahim Abubakar, Niveen M E Abu-Rmeileh, Tania C Aburto, Tom Achoki, Ademola Adelekan, Koranteng Adofo, Arsène K Adou, José C Adsuar, Ashkan Afshin, Emilie E Agardh, Mazin J Al Khabouri, Faris H Al Lami, Sayed Saidul Alam, Deena Alasfoor, Mohammed I Albittar, Miguel A Alegretti, Alicia V Aleman, Zewdie A Alemu, Rafael Alfonso-Cristancho, Samia Alhabib, Raghib Ali, Mohammed K Ali, François Alla, Peter Allebeck, Peter J Allen, Ubai Alsharif, Elena Alvarez, Nelson Alvis-Guzman, Adansi A Amankwaa, Azmeraw T Amare, Emmanuel A Ameh, Omid Ameli, Heresh Amini, Walid Ammar, Benjamin O Anderson, Carl Abelardo T Antonio, Palwasha Anwari, Solveig Argeseanu Cunningham, Johan Arnlöv, Valentina S Arsic Arsenijevic, Al Artaman, Rana J Asghar, Reza Assadi, Lydia S Atkins, Charles Atkinson, Marco A Avila, Baffour Awuah, Alaa Badawi, Maria C Bahit, Talal Bakfalouni, Kalpana Balakrishnan, Shivanthi Balalla, Ravi Kumar Balu, Amitava Banerjee, Ryan M Barber, Suzanne L Barker-Collo, Simon Barquera, Lars Barregard, Lope H Barrero, Tonatiuh Barrientos-Gutierrez, Ana C Basto-Abreu, Arindam Basu, Sanjay Basu, Mohammed O Basulaiman, Carolina Batis Ruvalcaba, Justin Beardsley, Neeraj Bedi, Tolesa Bekele, Michelle L Bell, Corina Benjet, Derrick A Bennett, Habib Benzian, Eduardo Bernabé, Tariku J Beyene, Neeraj Bhala, Ashish Bhalla, Zulfiqar A Bhutta, Boris Bikbov, Aref A Bin Abdulhak, Jed D Blore, Fiona M Blyth, Megan A Bohensky, Berrak Bora Başara, Guilherme Borges, Natan M Bornstein, Dipan Bose, Soufiane Boufous, Rupert R Bourne, Michael Brainin, Alexandra Brazinova, Nicholas J Breitborde, Hermann Brenner, Adam D M Briggs, David M Broday, Peter M Brooks, Nigel G Bruce, Traolach S Brugha, Bert Brunekreef, Rachelle Buchbinder, Linh N Bui, Gene Bukhman, Andrew G Bulloch, Michael Burch, Peter G J Burney, Ismael R Campos-Nonato, Julio C Campuzano, Alejandra J Cantoral, Jack Caravanos, Rosario Cárdenas, Elisabeth Cardis, David O Carpenter, Valeria Caso, Carlos A Castañeda-Orjuela, Ruben E Castro, Ferrán Catalá-López, Fiorella Cavalleri, Alanur Çavlin, Vineet K Chadha, Jung-Chen Chang, Fiona J Charlson, Honglei Chen, Wanqing Chen, Zhengming Chen, Peggy P Chiang, Odgerel Chimed-Ochir, Rajiv Chowdhury, Costas A Christophi, Ting-Wu Chuang, Sumeet S Chugh, Massimo Cirillo, Thomas K D Claßen, Valentina Colistro, Mercedes Colomar, Samantha M Colquhoun, Alejandra G Contreras, Cyrus Cooper, Kimberly Cooperrider, Leslie T Cooper, Josef Coresh, Karen J Courville, Michael H Criqui, Lucia Cuevas-Nasu, James Damsere-Derry, Hadi Danawi, Lalit Dandona, Rakhi Dandona, Paul I Dargan, Adrian Davis, Dragos V Davitoiu, Anand Dayama, E Filipa de Castro, Vanessa De la Cruz-Góngora, Diego De Leo, Graça de Lima, Louisa Degenhardt, Borja del Pozo-Cruz, Robert P Dellavalle, Kebede Deribe, Sarah Derrett, Don C Des Jarlais, Muluken Dessalegn, Gabrielle A deVeber, Karen M Devries, Samath D Dharmaratne, Mukesh K Dherani, Daniel Dicker, Eric L Ding, Klara Dokova, E Ray Dorsey, Tim R Driscoll, Leilei Duan, Adnan M Durrani, Beth E Ebel, Richard G Ellenbogen, Yousef M Elshrek, Matthias Endres, Sergey P Ermakov, Holly E Erskine, Babak Eshrati, Alireza Esteghamati, Saman Fahimi, Emerito Jose A Faraon, Farshad Farzadfar, Derek F J Fay, Valery L Feigin, Andrea B Feigl, Seyed-Mohammad Fereshtehnejad, Alize J Ferrari, Cleusa P Ferri, Abraham D Flaxman, Thomas D Fleming, Nataliya Foigt, Kyle J Foreman, Urbano Fra Paleo, Richard C Franklin, Belinda Gabbe, Lynne Gaffikin, Emmanuela Gakidou, Amiran Gamkrelidze, Fortuné G Gankpé, Ron T Gansevoort, Francisco A García-Guerra, Evariste Gasana, Johanna M Geleijnse, Bradford D Gessner, Pete Gething, Katherine B Gibney, Richard F Gillum, Ibrahim A M Ginawi, Maurice Giroud, Giorgia Giussani, Shifalika Goenka, Ketevan Goginashvili, Hector Gomez Dantes, Philimon Gona, Teresita Gonzalez de Cosio, Dinorah González-Castell, Carolyn C Gotay, Atsushi Goto, Hebe N Gouda, Richard L Guerrant, Harish C Gugnani, Francis Guillemin, David Gunnell, Rahul Gupta, Rajeev Gupta, Reyna A Gutiérrez, Nima Hafezi-Nejad, Holly Hagan, Maria Hagstromer, Yara A Halasa, Randah R Hamadeh, Mouhanad Hammami, Graeme J Hankey, Yuantao Hao, Hilda L Harb, Tilahun Nigatu Haregu, Josep Maria Haro, Rasmus Havmoeller, Simon I Hay, Mohammad T Hedayati, Ileana B Heredia-Pi, Lucia Hernandez, Kyle R Heuton, Pouria Heydarpour, Martha Hijar, Hans W Hoek, Howard J Hoffman, John C Hornberger, H Dean Hosgood, Damian G Hoy, Mohamed Hsairi, Guoqing Hu, Howard Hu, Cheng Huang, John J Huang, Bryan J Hubbell, Laetitia Huiart, Abdullatif Husseini, Marissa L Iannarone, Kim M Iburg, Bulat T Idrisov, Nayu Ikeda, Kaire Innos, Manami Inoue, Farhad Islami, Samaya Ismayilova, Kathryn H Jacobsen, Henrica A Jansen, Deborah L Jarvis, Simerjot K Jassal, Alejandra Jauregui, Sudha Jayaraman, Panniyammakal Jeemon, Paul N Jensen, Vivekanand Jha, Fan Jiang, Guohong Jiang, Ying Jiang, Jost B Jonas, Knud Juel, Haidong Kan, Sidibe S Kany Roseline, Nadim E Karam, André Karch, Corine K Karema, Ganesan Karthikeyan, Anil Kaul, Norito Kawakami, Dhruv S Kazi, Andrew H Kemp, Andre P Kengne, Andre Keren, Yousef S Khader, Shams Eldin Ali Hassan Khalifa, Ejaz A Khan, Young-Ho Khang, Shahab Khatibzadeh, Irma Khonelidze, Christian Kieling, Daniel Kim, Sungroul Kim, Yunjin Kim, Ruth W Kimokoti, Yohannes Kinfu, Jonas M Kinge, Brett M Kissela, Miia Kivipelto, Luke D Knibbs, Ann Kristin Knudsen, Yoshihiro Kokubo, M Rifat Kose, Soewarta Kosen, Alexander Kraemer, Michael Kravchenko, Sanjay Krishnaswami, Hans Kromhout, Tiffany Ku, Barthelemy Kuate Defo, Burcu Kucuk Bicer, Ernst J Kuipers, Chanda Kulkarni, Veena S Kulkarni, G Anil Kumar, Gene F Kwan, Taavi Lai, Arjun Lakshmana Balaji, Ratilal Lalloo, Tea Lallukka, Hilton Lam, Qing Lan, Van C Lansingh, Heidi J Larson, Anders Larsson, Dennis O Laryea, Pablo M Lavados, Alicia E Lawrynowicz, Janet L Leasher, Jong-Tae Lee, James Leigh, Ricky Leung, Miriam Levi, Yichong Li, Yongmei Li, Juan Liang, Xiaofeng Liang, Stephen S Lim, M Patrice Lindsay, Steven E Lipshultz, Shiwei Liu, Yang Liu, Belinda K Lloyd, Giancarlo Logroscino, Stephanie J London, Nancy Lopez, Joannie Lortet-Tieulent, Paulo A Lotufo, Rafael Lozano, Raimundas Lunevicius, Jixiang Ma, Stefan Ma, Vasco M P Machado, Michael F MacIntyre, Carlos Magis-Rodriguez, Abbas A Mahdi, Marek Majdan, Reza Malekzadeh, Srikanth Mangalam, Christopher C Mapoma, Marape Marape, Wagner Marcenes, David J Margolis, Christopher Margono, Guy B Marks, Randall V Martin, Melvin B Marzan, Mohammad T Mashal, Felix Masiye, Amanda J Mason-Jones, Kunihiro Matsushita, Richard Matzopoulos, Bongani M Mayosi, Tasara T Mazorodze, Abigail C McKay, Martin McKee, Abigail McLain, Peter A Meaney, Catalina Medina, Man Mohan Mehndiratta, Fabiola Mejia-Rodriguez, Wubegzier Mekonnen, Yohannes A Melaku, Michele Meltzer, Ziad A Memish, Walter Mendoza, George A Mensah, Atte Meretoja, Francis Apolinary Mhimbira, Renata Micha, Ted R Miller, Edward J Mills, Awoke Misganaw, Santosh Mishra, Norlinah Mohamed Ibrahim, Karzan A Mohammad, Ali H Mokdad, Glen L Mola, Lorenzo Monasta, Julio C Montañez Hernandez, Marcella Montico, Ami R Moore, Lidia Morawska, Rintaro Mori, Joanna Moschandreas, Wilkister N Moturi, Dariush Mozaffarian, Ulrich O Mueller, Mitsuru Mukaigawara, Erin C Mullany, Kinnari S Murthy, Mohsen Naghavi, Ziad Nahas, Aliya Naheed, Kovin S Naidoo, Luigi Naldi, Devina Nand, Vinay Nangia, K M Venkat Narayan, Denis Nash, Bruce Neal, Chakib Nejjari, Sudan P Neupane, Charles R Newton, Frida N Ngalesoni, Jean de Dieu Ngirabega, Grant Nguyen, Nhung T Nguyen, Mark J Nieuwenhuijsen, Muhammad I Nisar, José R Nogueira, Joan M Nolla, Sandra Nolte, Ole F Norheim, Rosana E Norman, Bo Norrving, Luke Nyakarahuka, In-Hwan Oh, Takayoshi Ohkubo, Bolajoko O Olusanya, Saad B Omer, John Nelson Opio, Ricardo Orozco, Rodolfo S Pagcatipunan, Amanda W Pain, Jeyaraj D Pandian, Carlo Irwin A Panelo, Christina Papachristou, Eun-Kee Park, Charles D Parry, Angel J Paternina Caicedo, Scott B Patten, Vinod K Paul, Boris I Pavlin, Neil Pearce, Lilia S Pedraza, Andrea Pedroza, Ljiljana Pejin Stokic, Ayfer Pekericli, David M Pereira, Rogelio Perez-Padilla, Fernando Perez-Ruiz, Norberto Perico, Samuel A L Perry, Aslam Pervaiz, Konrad Pesudovs, Carrie B Peterson, Max Petzold, Michael R Phillips, Hwee Pin Phua, Dietrich Plass, Dan Poenaru, Guilherme V Polanczyk, Suzanne Polinder, Constance D Pond, C Arden Pope, Daniel Pope, Svetlana Popova, Farshad Pourmalek, John Powles, Dorairaj Prabhakaran, Noela M Prasad, Dima M Qato, Amado D Quezada, D Alex A Quistberg, Lionel Racapé, Anwar Rafay, Kazem Rahimi, Vafa Rahimi-Movaghar, Sajjad Ur Rahman, Murugesan Raju, Ivo Rakovac, Saleem M Rana, Mayuree Rao, Homie Razavi, K Srinath Reddy, Amany H Refaat, Jürgen Rehm, Giuseppe Remuzzi, Antonio L Ribeiro, Patricia M Riccio, Lee Richardson, Anne Riederer, Margaret Robinson, Anna Roca, Alina Rodriguez, David Rojas-Rueda, Isabelle Romieu, Luca Ronfani, Robin Room, Nobhojit Roy, George M Ruhago, Lesley Rushton, Nsanzimana Sabin, Ralph L Sacco, Sukanta Saha, Ramesh Sahathevan, Mohammad Ali Sahraian, Joshua A Salomon, Deborah Salvo, Uchechukwu K Sampson, Juan R Sanabria, Luz Maria Sanchez, Tania G Sánchez-Pimienta, Lidia Sanchez-Riera, Logan Sandar, Itamar S Santos, Amir Sapkota, Maheswar Satpathy, James E Saunders, Monika Sawhney, Mete I Saylan, Peter Scarborough, Jürgen C Schmidt, Ione J C Schneider, Ben Schöttker, David C Schwebel, James G Scott, Soraya Seedat, Sadaf G Sepanlou, Berrin Serdar, Edson E Servan-Mori, Gavin Shaddick, Saeid Shahraz, Teresa Shamah Levy, Siyi Shangguan, Jun She, Sara Sheikhbahaei, Kenji Shibuya, Hwashin H Shin, Yukito Shinohara, Rahman Shiri, Kawkab Shishani, Ivy Shiue, Inga D Sigfusdottir, Donald H Silberberg, Edgar P Simard, Shireen Sindi, Abhishek Singh, Gitanjali M Singh, Jasvinder A Singh, Vegard Skirbekk, Karen Sliwa, Michael Soljak, Samir Soneji, Kjetil Søreide, Sergey Soshnikov, Luciano A Sposato, Chandrashekhar T Sreeramareddy, Nicolas J C Stapelberg, Vasiliki Stathopoulou, Nadine Steckling, Dan J Stein, Murray B Stein, Natalie Stephens, Heidi Stöckl, Kurt Straif, Konstantinos Stroumpoulis, Lela Sturua, Bruno F Sunguya, Soumya Swaminathan, Mamta Swaroop, Bryan L Sykes, Karen M Tabb, Ken Takahashi, Roberto T Talongwa, Nikhil Tandon, David Tanne, Marcel Tanner, Mohammad Tavakkoli, Braden J Te Ao, Carolina M Teixeira, Martha M Téllez Rojo, Abdullah S Terkawi, José Luis Texcalac-Sangrador, Sarah V Thackway, Blake Thomson, Andrew L Thorne-Lyman, Amanda G Thrift, George D Thurston, Taavi Tillmann, Myriam Tobollik, Marcello Tonelli, Fotis Topouzis, Jeffrey A Towbin, Hideaki Toyoshima, Jefferson Traebert, Bach X Tran, Leonardo Trasande, Matias Trillini, Ulises Trujillo, Zacharie Tsala Dimbuene, Miltiadis Tsilimbaris, Emin Murat Tuzcu, Uche S Uchendu, Kingsley N Ukwaja, Selen B Uzun, Steven van de Vijver, Rita Van Dingenen, Coen H van Gool, Jim van Os, Yuri Y Varakin, Tommi J Vasankari, Ana Maria N Vasconcelos, Monica S Vavilala, Lennert J Veerman, Gustavo Velasquez-Melendez, N Venketasubramanian, Lakshmi Vijayakumar, Salvador Villalpando, Francesco S Violante, Vasiliy Victorovich Vlassov, Stein Emil Vollset, Gregory R Wagner, Stephen G Waller, Mitchell T Wallin, Xia Wan, Haidong Wang, JianLi Wang, Linhong Wang, Wenzhi Wang, Yanping Wang, Tati S Warouw, Charlotte H Watts, Scott Weichenthal, Elisabete Weiderpass, Robert G Weintraub, Andrea Werdecker, K Ryan Wessells, Ronny Westerman, Harvey A Whiteford, James D Wilkinson, Hywel C Williams, Thomas N Williams, Solomon M Woldeyohannes, Charles D A Wolfe, John Q Wong, Anthony D Woolf, Jonathan L Wright, Brittany Wurtz, Gelin Xu, Lijing L Yan, Gonghuan Yang, Yuichiro Yano, Pengpeng Ye, Muluken Yenesew, Gökalp K Yentür, Paul Yip, Naohiro Yonemoto, Seok-Jun Yoon, Mustafa Z Younis, Zourkaleini Younoussi, Chuanhua Yu, Maysaa E Zaki, Yong Zhao, Yingfeng Zheng, Maigeng Zhou, Jun Zhu, Shankuan Zhu, Xiaonong Zou, Joseph R Zunt, Alan D Lopez, Theo Vos, Christopher J Murray
BACKGROUND: The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD 2013) is the first of a series of annual updates of the GBD. Risk factor quantification, particularly of modifiable risk factors, can help to identify emerging threats to population health and opportunities for prevention. The GBD 2013 provides a timely opportunity to update the comparative risk assessment with new data for exposure, relative risks, and evidence on the appropriate counterfactual risk distribution...
December 5, 2015: Lancet
https://www.readbyqxmd.com/read/26346685/reliability-of-repeated-forensic-evaluations-of-legal-sanity
#15
Iwona Kacperska, Janusz Heitzman, Tomasz Bąk, Anna Walczyna Leśko, Małgorzata Opio
Criminal responsibility evaluation is a very complex and controversial issue due to the gravity of its consequences. Polish legislation allows courts to request multiple sanity evaluations. The purpose of this study was to assess the extent of agreement on sanity evaluations in written evidence provided by experts of criminal cases in Poland. A total of 381 forensic evaluation reports addressing 117 criminal defendants were analysed. In sixty eight cases, there was more than one forensic evaluation report containing an assessment of legal sanity, including forty one cases containing two assessments of criminal responsibility, seventeen containing three assessments, eight containing four assessments and two containing five assessments...
January 2016: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/26321261/global-regional-and-national-disability-adjusted-life-years-dalys-for-306-diseases-and-injuries-and-healthy-life-expectancy-hale-for-188-countries-1990-2013-quantifying-the-epidemiological-transition
#16
Christopher J L Murray, Ryan M Barber, Kyle J Foreman, Ayse Abbasoglu Ozgoren, Foad Abd-Allah, Semaw F Abera, Victor Aboyans, Jerry P Abraham, Ibrahim Abubakar, Laith J Abu-Raddad, Niveen M Abu-Rmeileh, Tom Achoki, Ilana N Ackerman, Zanfina Ademi, Arsène K Adou, José C Adsuar, Ashkan Afshin, Emilie E Agardh, Sayed Saidul Alam, Deena Alasfoor, Mohammed I Albittar, Miguel A Alegretti, Zewdie A Alemu, Rafael Alfonso-Cristancho, Samia Alhabib, Raghib Ali, François Alla, Peter Allebeck, Mohammad A Almazroa, Ubai Alsharif, Elena Alvarez, Nelson Alvis-Guzman, Azmeraw T Amare, Emmanuel A Ameh, Heresh Amini, Walid Ammar, H Ross Anderson, Benjamin O Anderson, Carl Abelardo T Antonio, Palwasha Anwari, Johan Arnlöv, Valentina S Arsic Arsenijevic, Al Artaman, Rana J Asghar, Reza Assadi, Lydia S Atkins, Marco A Avila, Baffour Awuah, Victoria F Bachman, Alaa Badawi, Maria C Bahit, Kalpana Balakrishnan, Amitava Banerjee, Suzanne L Barker-Collo, Simon Barquera, Lars Barregard, Lope H Barrero, Arindam Basu, Sanjay Basu, Mohammed O Basulaiman, Justin Beardsley, Neeraj Bedi, Ettore Beghi, Tolesa Bekele, Michelle L Bell, Corina Benjet, Derrick A Bennett, Isabela M Bensenor, Habib Benzian, Eduardo Bernabé, Amelia Bertozzi-Villa, Tariku J Beyene, Neeraj Bhala, Ashish Bhalla, Zulfiqar A Bhutta, Kelly Bienhoff, Boris Bikbov, Stan Biryukov, Jed D Blore, Christopher D Blosser, Fiona M Blyth, Megan A Bohensky, Ian W Bolliger, Berrak Bora Başara, Natan M Bornstein, Dipan Bose, Soufiane Boufous, Rupert R A Bourne, Lindsay N Boyers, Michael Brainin, Carol E Brayne, Alexandra Brazinova, Nicholas J K Breitborde, Hermann Brenner, Adam D Briggs, Peter M Brooks, Jonathan C Brown, Traolach S Brugha, Rachelle Buchbinder, Geoffrey C Buckle, Christine M Budke, Anne Bulchis, Andrew G Bulloch, Ismael R Campos-Nonato, Hélène Carabin, Jonathan R Carapetis, Rosario Cárdenas, David O Carpenter, Valeria Caso, Carlos A Castañeda-Orjuela, Ruben E Castro, Ferrán Catalá-López, Fiorella Cavalleri, Alanur Çavlin, Vineet K Chadha, Jung-Chen Chang, Fiona J Charlson, Honglei Chen, Wanqing Chen, Peggy P Chiang, Odgerel Chimed-Ochir, Rajiv Chowdhury, Hanne Christensen, Costas A Christophi, Massimo Cirillo, Matthew M Coates, Luc E Coffeng, Megan S Coggeshall, Valentina Colistro, Samantha M Colquhoun, Graham S Cooke, Cyrus Cooper, Leslie T Cooper, Luis M Coppola, Monica Cortinovis, Michael H Criqui, John A Crump, Lucia Cuevas-Nasu, Hadi Danawi, Lalit Dandona, Rakhi Dandona, Emily Dansereau, Paul I Dargan, Gail Davey, Adrian Davis, Dragos V Davitoiu, Anand Dayama, Diego De Leo, Louisa Degenhardt, Borja Del Pozo-Cruz, Robert P Dellavalle, Kebede Deribe, Sarah Derrett, Don C Des Jarlais, Muluken Dessalegn, Samath D Dharmaratne, Mukesh K Dherani, Cesar Diaz-Torné, Daniel Dicker, Eric L Ding, Klara Dokova, E Ray Dorsey, Tim R Driscoll, Leilei Duan, Herbert C Duber, Beth E Ebel, Karen M Edmond, Yousef M Elshrek, Matthias Endres, Sergey P Ermakov, Holly E Erskine, Babak Eshrati, Alireza Esteghamati, Kara Estep, Emerito Jose A Faraon, Farshad Farzadfar, Derek F Fay, Valery L Feigin, David T Felson, Seyed-Mohammad Fereshtehnejad, Jefferson G Fernandes, Alize J Ferrari, Christina Fitzmaurice, Abraham D Flaxman, Thomas D Fleming, Nataliya Foigt, Mohammad H Forouzanfar, F Gerry R Fowkes, Urbano Fra Paleo, Richard C Franklin, Thomas Fürst, Belinda Gabbe, Lynne Gaffikin, Fortuné G Gankpé, Johanna M Geleijnse, Bradford D Gessner, Peter Gething, Katherine B Gibney, Maurice Giroud, Giorgia Giussani, Hector Gomez Dantes, Philimon Gona, Diego González-Medina, Richard A Gosselin, Carolyn C Gotay, Atsushi Goto, Hebe N Gouda, Nicholas Graetz, Harish C Gugnani, Rahul Gupta, Rajeev Gupta, Reyna A Gutiérrez, Juanita Haagsma, Nima Hafezi-Nejad, Holly Hagan, Yara A Halasa, Randah R Hamadeh, Hannah Hamavid, Mouhanad Hammami, Jamie Hancock, Graeme J Hankey, Gillian M Hansen, Yuantao Hao, Hilda L Harb, Josep Maria Haro, Rasmus Havmoeller, Simon I Hay, Roderick J Hay, Ileana B Heredia-Pi, Kyle R Heuton, Pouria Heydarpour, Hideki Higashi, Martha Hijar, Hans W Hoek, Howard J Hoffman, H Dean Hosgood, Mazeda Hossain, Peter J Hotez, Damian G Hoy, Mohamed Hsairi, Guoqing Hu, Cheng Huang, John J Huang, Abdullatif Husseini, Chantal Huynh, Marissa L Iannarone, Kim M Iburg, Kaire Innos, Manami Inoue, Farhad Islami, Kathryn H Jacobsen, Deborah L Jarvis, Simerjot K Jassal, Sun Ha Jee, Panniyammakal Jeemon, Paul N Jensen, Vivekanand Jha, Guohong Jiang, Ying Jiang, Jost B Jonas, Knud Juel, Haidong Kan, André Karch, Corine K Karema, Chante Karimkhani, Ganesan Karthikeyan, Nicholas J Kassebaum, Anil Kaul, Norito Kawakami, Konstantin Kazanjan, Andrew H Kemp, Andre P Kengne, Andre Keren, Yousef S Khader, Shams Eldin A Khalifa, Ejaz A Khan, Gulfaraz Khan, Young-Ho Khang, Christian Kieling, Daniel Kim, Sungroul Kim, Yunjin Kim, Yohannes Kinfu, Jonas M Kinge, Miia Kivipelto, Luke D Knibbs, Ann Kristin Knudsen, Yoshihiro Kokubo, Soewarta Kosen, Sanjay Krishnaswami, Barthelemy Kuate Defo, Burcu Kucuk Bicer, Ernst J Kuipers, Chanda Kulkarni, Veena S Kulkarni, G Anil Kumar, Hmwe H Kyu, Taavi Lai, Ratilal Lalloo, Tea Lallukka, Hilton Lam, Qing Lan, Van C Lansingh, Anders Larsson, Alicia E B Lawrynowicz, Janet L Leasher, James Leigh, Ricky Leung, Carly E Levitz, Bin Li, Yichong Li, Yongmei Li, Stephen S Lim, Maggie Lind, Steven E Lipshultz, Shiwei Liu, Yang Liu, Belinda K Lloyd, Katherine T Lofgren, Giancarlo Logroscino, Katharine J Looker, Joannie Lortet-Tieulent, Paulo A Lotufo, Rafael Lozano, Robyn M Lucas, Raimundas Lunevicius, Ronan A Lyons, Stefan Ma, Michael F Macintyre, Mark T Mackay, Marek Majdan, Reza Malekzadeh, Wagner Marcenes, David J Margolis, Christopher Margono, Melvin B Marzan, Joseph R Masci, Mohammad T Mashal, Richard Matzopoulos, Bongani M Mayosi, Tasara T Mazorodze, Neil W Mcgill, John J Mcgrath, Martin Mckee, Abigail Mclain, Peter A Meaney, Catalina Medina, Man Mohan Mehndiratta, Wubegzier Mekonnen, Yohannes A Melaku, Michele Meltzer, Ziad A Memish, George A Mensah, Atte Meretoja, Francis A Mhimbira, Renata Micha, Ted R Miller, Edward J Mills, Philip B Mitchell, Charles N Mock, Norlinah Mohamed Ibrahim, Karzan A Mohammad, Ali H Mokdad, Glen L D Mola, Lorenzo Monasta, Julio C Montañez Hernandez, Marcella Montico, Thomas J Montine, Meghan D Mooney, Ami R Moore, Maziar Moradi-Lakeh, Andrew E Moran, Rintaro Mori, Joanna Moschandreas, Wilkister N Moturi, Madeline L Moyer, Dariush Mozaffarian, William T Msemburi, Ulrich O Mueller, Mitsuru Mukaigawara, Erin C Mullany, Michele E Murdoch, Joseph Murray, Kinnari S Murthy, Mohsen Naghavi, Aliya Naheed, Kovin S Naidoo, Luigi Naldi, Devina Nand, Vinay Nangia, K M Venkat Narayan, Chakib Nejjari, Sudan P Neupane, Charles R Newton, Marie Ng, Frida N Ngalesoni, Grant Nguyen, Muhammad I Nisar, Sandra Nolte, Ole F Norheim, Rosana E Norman, Bo Norrving, Luke Nyakarahuka, In-Hwan Oh, Takayoshi Ohkubo, Summer L Ohno, Bolajoko O Olusanya, John Nelson Opio, Katrina Ortblad, Alberto Ortiz, Amanda W Pain, Jeyaraj D Pandian, Carlo Irwin A Panelo, Christina Papachristou, Eun-Kee Park, Jae-Hyun Park, Scott B Patten, George C Patton, Vinod K Paul, Boris I Pavlin, Neil Pearce, David M Pereira, Rogelio Perez-Padilla, Fernando Perez-Ruiz, Norberto Perico, Aslam Pervaiz, Konrad Pesudovs, Carrie B Peterson, Max Petzold, Michael R Phillips, Bryan K Phillips, David E Phillips, Frédéric B Piel, Dietrich Plass, Dan Poenaru, Suzanne Polinder, Daniel Pope, Svetlana Popova, Richie G Poulton, Farshad Pourmalek, Dorairaj Prabhakaran, Noela M Prasad, Rachel L Pullan, Dima M Qato, D Alex Quistberg, Anwar Rafay, Kazem Rahimi, Sajjad U Rahman, Murugesan Raju, Saleem M Rana, Homie Razavi, K Srinath Reddy, Amany Refaat, Giuseppe Remuzzi, Serge Resnikoff, Antonio L Ribeiro, Lee Richardson, Jan Hendrik Richardus, D Allen Roberts, David Rojas-Rueda, Luca Ronfani, Gregory A Roth, Dietrich Rothenbacher, David H Rothstein, Jane T Rowley, Nobhojit Roy, George M Ruhago, Mohammad Y Saeedi, Sukanta Saha, Mohammad Ali Sahraian, Uchechukwu K A Sampson, Juan R Sanabria, Logan Sandar, Itamar S Santos, Maheswar Satpathy, Monika Sawhney, Peter Scarborough, Ione J Schneider, Ben Schöttker, Austin E Schumacher, David C Schwebel, James G Scott, Soraya Seedat, Sadaf G Sepanlou, Peter T Serina, Edson E Servan-Mori, Katya A Shackelford, Amira Shaheen, Saeid Shahraz, Teresa Shamah Levy, Siyi Shangguan, Jun She, Sara Sheikhbahaei, Peilin Shi, Kenji Shibuya, Yukito Shinohara, Rahman Shiri, Kawkab Shishani, Ivy Shiue, Mark G Shrime, Inga D Sigfusdottir, Donald H Silberberg, Edgar P Simard, Shireen Sindi, Abhishek Singh, Jasvinder A Singh, Lavanya Singh, Vegard Skirbekk, Erica Leigh Slepak, Karen Sliwa, Samir Soneji, Kjetil Søreide, Sergey Soshnikov, Luciano A Sposato, Chandrashekhar T Sreeramareddy, Jeffrey D Stanaway, Vasiliki Stathopoulou, Dan J Stein, Murray B Stein, Caitlyn Steiner, Timothy J Steiner, Antony Stevens, Andrea Stewart, Lars J Stovner, Konstantinos Stroumpoulis, Bruno F Sunguya, Soumya Swaminathan, Mamta Swaroop, Bryan L Sykes, Karen M Tabb, Ken Takahashi, Nikhil Tandon, David Tanne, Marcel Tanner, Mohammad Tavakkoli, Hugh R Taylor, Braden J Te Ao, Fabrizio Tediosi, Awoke M Temesgen, Tara Templin, Margreet Ten Have, Eric Y Tenkorang, Abdullah S Terkawi, Blake Thomson, Andrew L Thorne-Lyman, Amanda G Thrift, George D Thurston, Taavi Tillmann, Marcello Tonelli, Fotis Topouzis, Hideaki Toyoshima, Jefferson Traebert, Bach X Tran, Matias Trillini, Thomas Truelsen, Miltiadis Tsilimbaris, Emin M Tuzcu, Uche S Uchendu, Kingsley N Ukwaja, Eduardo A Undurraga, Selen B Uzun, Wim H Van Brakel, Steven Van De Vijver, Coen H van Gool, Jim Van Os, Tommi J Vasankari, N Venketasubramanian, Francesco S Violante, Vasiliy V Vlassov, Stein Emil Vollset, Gregory R Wagner, Joseph Wagner, Stephen G Waller, Xia Wan, Haidong Wang, Jianli Wang, Linhong Wang, Tati S Warouw, Scott Weichenthal, Elisabete Weiderpass, Robert G Weintraub, Wang Wenzhi, Andrea Werdecker, Ronny Westerman, Harvey A Whiteford, James D Wilkinson, Thomas N Williams, Charles D Wolfe, Timothy M Wolock, Anthony D Woolf, Sarah Wulf, Brittany Wurtz, Gelin Xu, Lijing L Yan, Yuichiro Yano, Pengpeng Ye, Gökalp K Yentür, Paul Yip, Naohiro Yonemoto, Seok-Jun Yoon, Mustafa Z Younis, Chuanhua Yu, Maysaa E Zaki, Yong Zhao, Yingfeng Zheng, David Zonies, Xiaonong Zou, Joshua A Salomon, Alan D Lopez, Theo Vos
BACKGROUND: The Global Burden of Disease Study 2013 (GBD 2013) aims to bring together all available epidemiological data using a coherent measurement framework, standardised estimation methods, and transparent data sources to enable comparisons of health loss over time and across causes, age-sex groups, and countries. The GBD can be used to generate summary measures such as disability-adjusted life-years (DALYs) and healthy life expectancy (HALE) that make possible comparative assessments of broad epidemiological patterns across countries and time...
November 28, 2015: Lancet
https://www.readbyqxmd.com/read/26267141/evaluation-of-integrated-community-case-management-in-eight-districts-of-central-uganda
#17
Denis Mubiru, Robert Byabasheija, John Baptist Bwanika, Joslyn Edelstein Meier, Godfrey Magumba, Flavia Mpanga Kaggwa, Jackson Ojera Abusu, Alex Chono Opio, Charles Clarke Lodda, Jaanki Patel, Theresa Diaz
OBJECTIVE: Evidence is limited on whether Integrated Community Case Management (iCCM) improves treatment coverage of the top causes of childhood mortality (acute respiratory illnesses (ARI), diarrhoea and malaria). The coverage impact of iCCM in Central Uganda was evaluated. METHODS: Between July 2010 and December 2012 a pre-post quasi-experimental study in eight districts with iCCM was conducted; 3 districts without iCCM served as controls. A two-stage household cluster survey at baseline (n = 1036 and 1042) and end line (n = 3890 and 3844) was done in the intervention and comparison groups respectively...
2015: PloS One
https://www.readbyqxmd.com/read/26207986/improving-the-quality-of-voluntary-medical-male-circumcision-through-use-of-the-continuous-quality-improvement-approach-a-pilot-in-30-pepfar-supported-sites-in-uganda
#18
John Byabagambi, Pamela Marks, Humphrey Megere, Esther Karamagi, Sarah Byakika, Alex Opio, Jacqueline Calnan, Emmanuel Njeuhmeli
BACKGROUND: Uganda adopted voluntary medical male circumcision (VMMC) (also called Safe Male Circumcision in Uganda), as part of its HIV prevention strategy in 2010. Since then, the Ministry of Health (MOH) has implemented VMMC mostly with support from the United States President's Emergency Plan for AIDS Relief (PEPFAR) through its partners. In 2012, two PEPFAR-led external quality assessments evaluated compliance of service delivery sites with minimum quality standards. Quality gaps were identified, including lack of standardized forms or registers, lack of documentation of client consent, poor preparedness for emergencies and use of untrained service providers...
2015: PloS One
https://www.readbyqxmd.com/read/26124776/hepatitis-b-and-hiv-co-infection-is-still-treated-using-lamivudine-only-antiretroviral-therapy-combination-in-uganda
#19
Ponsiano Ocama, Emmanuel Seremba, Betty Apica, Kenneth Opio
BACKGROUND: Hepatitis B virus (HBV) and HIV are endemic in Uganda. Co-infection is common and leads to rapid progression of liver disease. Burden of co-infection is unknown yet most patients are on lamivudine-only ART where resistance is frequent. Most patients are initiated on antiretroviral therapy (ART) without knowing their HBV status. OBJECTIVES: To determine burden of co-infection and HBV viral suppression among patients on ART in Northern Uganda. METHODS: We recruited HIV infected adult patients on ART in a cross-sectional study...
June 2015: African Health Sciences
https://www.readbyqxmd.com/read/26117397/environmental-impacts-of-beef-production-review-of-challenges-and-perspectives-for-durability
#20
REVIEW
Pierre J Gerber, Anne Mottet, Carolyn I Opio, Alessandra Falcucci, Félix Teillard
Beef makes a substantial contribution to food security, providing protein, energy and also essential micro-nutrients to human populations. Rumination allows cattle - and other ruminant species - to digest fibrous feeds that cannot be directly consumed by humans and thus to make a net positive contribution to food balances. This contribution is of particular importance in marginal areas, where agro-ecological conditions and weak infrastructures do not offer much alternative. It is also valuable where cattle convert crop residues and by-products into edible products and where they contribute to soil fertility through their impact on nutrients and organic matter cycles...
November 2015: Meat Science
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