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https://www.readbyqxmd.com/read/29782309/in-memoriam-assistant-professor-kre%C3%A5-imir-kostovi%C3%A4-md-phd-16-october-1969-15-october-2017
#1
Branka Marinović
On a Sunday afternoon almost six months ago, we were deeply moved by the news that our Krešimir is no longer with us. The sad news spread from Sarajevo with the speed only most horrible and saddest news can achieve. And everybody who was reached by these news wondered whether it was possible and whether it was true. Because our professor Kostović left us a day before his 48th birthday. Krešimir Kostović was born on the 16th October 1969 in Zagreb, where he completed primary and secondary education. He enrolled at the University of Zagreb School of Medicine in 1988, and got his medical degree in 1995...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29774812/robot-assisted-simple-prostatectomy-by-an-extraperitoneal-approach
#2
Jens-Uwe Stolzenburg, Panagiotis Kallidonis, Iason Kyriazis, Dimitrios Kotsiris, Panteleimon Ntasiotis, Evangelos N Liatsikos
The incidence of symptomatic benign prostate hyperplasia and bladder outlet obstruction has increased during the last two decades. Most of men are treated conservatively. When medical therapy is inadequate to relief symptoms, surgical treatment is necessary. Absolute indications for surgical treatment are gross hematuria, recurrent urinary infections and retentions as well as bladder stones. With advent of minimally invasive surgery, large prostates tend to be treated either endoscopically or laparoscopically (including robotic assistance)...
May 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29774392/cost-effectiveness-of-ventricular-assist-device-destination-therapy-for-advanced-heart-failure-in-duchenne-muscular-dystrophy
#3
Defne A Magnetta, JaHyun Kang, Peter D Wearden, Kenneth J Smith, Brian Feingold
Destination ventricular assist device therapy (DT-VAD) is well accepted in select adults with medically refractory heart failure (HF) who are not transplant candidates; however, its use in younger patients with progressive diseases is unclear. We sought to evaluate the cost-effectiveness of DT-VAD in Duchenne muscular dystrophy (DMD) patients with advanced HF. We created a Markov-state transition model (5-year horizon) to compare survival, costs, and quality of life (QOL) between medical management and DT-VAD in DMD with advanced HF...
May 17, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29770082/first-reported-case-of-multidrug-resistant-candida-auris-in-canada
#4
I S Schwartz, G W Hammond
Candida auris is a fungal pathogen that has recently emerged as a global threat to public health. It was first described in Japan in 2009 and has since been reported in 17 countries on five continents. This case report describes the first reported case of multidrug-resistant C. auris in Canada. In May 2017, a 64-year-old individual was evaluated for chronic otitis externa. Past medical history included a recent hospitalization in India for elective oral surgery that was complicated by an odontogenic brain abscess...
July 6, 2017: Canada Communicable Disease Report, Relevé des Maladies Transmissibles Au Canada
https://www.readbyqxmd.com/read/29764034/-application-of-low-profile-visualized-intraluminal-support-lvis-stents-in-assisting-coil-embolization-of-intracranial-aneurysms
#5
D C Xu, J Li, Z Q Jiang
Objective: To evaluate the safety and effectiveness of application of LVIS stent-assisted coiling endovascular procedures in cerebral aneurysms . Methods: The clinical data of 41 patients with intracranial aneurysms , which were performed in LVIS stent-assisted coiling endovascular therapies from June 2015 to October 2017 in The First Affiliated Hospital of Bengbu Medical College were analyzed retrospectively. 13 patients were unruptured and 28 patients were ruptured. Immediate angiography outcomes and follow-up angiography outcomes were assessed by DSA...
May 8, 2018: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/29761426/predictors-of-self-reported-adherence-to-direct-oral-anticoagulation-in-a-population-of-elderly-men-and-women-with-non-valvular-atrial-fibrillation
#6
Andrea P Rossi, Roberto Facchinetti, Elena Ferrari, Nicole Nori, Selena Sant, Elena Masciocchi, Elena Zoico, Francesco Fantin, Gloria Mazzali, Mauro Zamboni
There is a general lack of studies evaluating medication adherence with self-report scales for elderly patients in treatment with direct oral anticoagulants (DOACs). The aim of the study was to assess the degree of adherence to DOAC therapy in a population of elderly outpatients aged 65 years or older affected by non-valvular atrial fibrillation (NVAF), using the 4-item Morisky Medication Adherence Scale, and to identify potential factors, including the geriatric multidimensional evaluation, which can affect adherence in the study population...
May 14, 2018: Journal of Thrombosis and Thrombolysis
https://www.readbyqxmd.com/read/29759560/cardiotoxic-effects-of-chemotherapy-a-review-of-both-cytotoxic-and-molecular-targeted-oncology-therapies-and-their-effect-on-the-cardiovascular-system
#7
REVIEW
Hani M Babiker, Ali McBride, Michael Newton, Leigh M Boehmer, Adrienne Goeller Drucker, Mollie Gowan, Manouchkathe Cassagnol, Todd D Camenisch, Faiz Anwer, James M Hollands
Cardiotoxic effects of chemotherapy and targeted drugs are ubiquitous and challenging in the field of oncology therapeutics. The broad spectrum of toxicities ranging from ischemic, hypertensive, cardiomyopathic, and arrhythmic complications can present as a significant challenge for clinicians treating cancer patients. If early diagnosis and intervention of cardiotoxic complications is missed, this can lead to delay or abrogation of planned treatment, which can potentially culminate to significant morbidity due to not only the cardiotoxic complications but also the progression of cancer...
June 2018: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/29759276/hypnotic-discontinuation-in-chronic-insomnia
#8
REVIEW
Jonathan P Hintze, Jack D Edinger
Patients with chronic insomnia are commonly prescribed hypnotic medications. The long-term effects of chronic hypnotics are not known and discontinuation is encouraged but often difficult to achieve. A gradual taper is preferred to abrupt cessation to avoid rebound insomnia and withdrawal symptoms. Written information provided to the patient about medication discontinuation may be helpful. Cognitive behavioral therapy or behavioral therapies alone can improve hypnotic discontinuation outcomes. There is limited evidence for adjunct medications to assist in hypnotic cessation for insomnia...
June 2018: Sleep Medicine Clinics
https://www.readbyqxmd.com/read/29756588/toward-a-shared-care-model-of-relapsing-remitting-multiple-sclerosis-role-of-the-primary-care-practitioner
#9
Jiwon Oh, Marie-Sarah Gagné-Brosseau, Melanie Guenette, Catherine Larochelle, François Lemieux, Suresh Menon, Sarah A Morrow, Laurence Poliquin-Lasnier, Chantal Roy-Hewitson, Carolina Rush, Anne-Marie Trudelle, Paul S Giacomini
The objective of this study was to develop a shared-care model to enable primary-care physicians to participate more fully in meeting the complex, multidisciplinary healthcare needs of patients with multiple sclerosis (MS). DESIGN: The design consisted of development of consensus recommendations and a shared-care algorithm. PARTICIPANTS: A working group of 11 Canadian neurologists involved in the management of patients with MS were included in this study. MAIN MESSAGE: The clinical management of patients with multiple sclerosis is increasing in complexity as new disease-modifying therapies (DMTs) become available, and ongoing safety monitoring is required...
May 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29756211/appropriateness-criteria-predict-outcomes-for-sinus-surgery-and-may-aid-in-future-patient-selection
#10
Daniel M Beswick, Jess C Mace, Zachary M Soler, Noel F Ayoub, Luke Rudmik, Adam S DeConde, Timothy L Smith
OBJECTIVES: Appropriateness criteria to determine surgical candidacy for chronic rhinosinusitis (CRS) have recently been described. This study stratified patients who underwent endoscopic sinus surgery (ESS) according to these new appropriateness criteria and evaluated postoperative improvements among appropriateness categories. METHODS: Adult patients with uncomplicated CRS electing ESS were prospectively enrolled in a multi-institutional cohort study between March 2011 and June 2015 to assess outcomes...
May 14, 2018: Laryngoscope
https://www.readbyqxmd.com/read/29753335/external-beam-planning-module-of-eclipse-for-external-beam-radiation-therapy
#11
REVIEW
Cheng B Saw, SiCong Li, Frank Battin, Janice McKeague, Christopher A Peters
Eclipse is a 3-dimensional (3D) treatment planning system for radiation therapy offered by Varian Medical Systems, Inc. The system has the network connectivity for the electronic transfer of image datasets and digital data communication among different equipment. The scope of this project for this special issue of Medical Dosimetry on 3D treatment planning systems is the assessment of planning tools in the external beam planning module of Eclipse to generate optimized treatment plans for patients undergoing external beam radiation therapy...
July 2018: Medical Dosimetry: Official Journal of the American Association of Medical Dosimetrists
https://www.readbyqxmd.com/read/29747449/iron-oxide-colloidal-nanoclusters-as-theranostic-vehicles-and-their-interactions-at-the-cellular-level
#12
Athanasia Kostopoulou, Konstantinos Brintakis, Eirini Fragogeorgi, Amalia Anthousi, Liberato Manna, Sylvie Begin-Colin, Claire Billotey, Anthi Ranella, George Loudos, Irene Athanassakis, Alexandros Lappas
Advances in surfactant-assisted chemical approaches have led the way for the exploitation of nanoscale inorganic particles in medical diagnosis and treatment. In this field, magnetically-driven multimodal nanotools that perform both detection and therapy, well-designed in size, shape and composition, are highly advantageous. Such a theranostic material—which entails the controlled assembly of smaller (maghemite) nanocrystals in a secondary motif that is highly dispersible in aqueous media—is discussed here...
May 9, 2018: Nanomaterials
https://www.readbyqxmd.com/read/29746258/gi-bleeding-during-cf-lvad-support-state-of-the-field
#13
Rachna Kataria, Ulrich P Jorde
Continuous-flow left ventricular assist devices (CF-LVADs) are increasingly used for the management of advanced heart failure refractory to optimal medical therapy. Despite the encouraging outcomes with CF-LVADs, gastrointestinal bleeding (GIB) continues to be a rather concerning complication resulting in increased rates of readmission and increased morbidity. The exact pathophysiology of CF-LVAD associated GIB remains poorly understood and this lack of knowledge limits our ability to control this morbid complication...
May 9, 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29745361/a-window-beneath-the-skin-how-computed-tomography-assessment-of-body-composition-can-assist-in-the-identification-of-hidden-wasting-conditions-in-oncology-that-profoundly-impact-outcomes
#14
L E Daly, C M Prado, A M Ryan
Advancements in image-based technologies and body composition research over the past decade has led to increased understanding of the importance of muscle abnormalities, such as low muscle mass (sarcopenia), and more recently low muscle attenuation (MA), as important prognostic indicators of unfavourable outcomes in patients with cancer. Muscle abnormalities can be highly prevalent in patients with cancer (ranging between 10 and 90 %), depending on the cohort under investigation and diagnostic criteria used...
May 2018: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/29739380/efficacy-analysis-of-self-help-position-therapy-after-holmium-laser-lithotripsy-via-flexible-ureteroscopy
#15
Jie Yang, Rong-Zhen Tao, Pei Lu, Meng-Xing Chen, Xin-Kun Huang, Ke-Liang Chen, Ying-Heng Huang, Xiao-Rong He, Li-di Wan, Jing Wang, Xin Tang, Wei Zhang
BACKGROUND: To observe the efficacy of self-help position therapy (SHPT) after holmium laser lithotripsy via flexible ureteroscopy (FURS). METHODS: From January 2010 to November 2015, 736 nephrolithiasis patients who had received FURS lithotripsy were analyzed retrospectively. In position group, 220 cases accepted SHPT after lithotripsies, and 428 cases as control, coming from another independent inpatient area in the same center. The stone-free status (SFS) between two groups were compared at the 2nd, 4th and 12th week ends by X-ray examinations...
May 8, 2018: BMC Urology
https://www.readbyqxmd.com/read/29735615/facilitators-and-barriers-to-naloxone-kit-use-among-opioid-dependent-patients-enrolled-in-medication-assisted-therapy-clinics-in-north-carolina
#16
Prasana Khatiwoda, Rae Jean Proeschold-Bell, Christina S Meade, Lawrence P Park, Scott Proescholdbell
BACKGROUND Naloxone-an opioid antagonist that reverses the effects of opioids-is increasingly being distributed in non-medical settings. We sought to identify the facilitators of, and barriers to, opioid users using naloxone kits in North Carolina. METHODS In 2015, we administered a 15-item survey to a convenience sample of 100 treatment seekers at 4 methadone/buprenorphine Medication Assisted Therapy (MAT) clinics in North Carolina. RESULTS Seventy-four percent of participants reported having ever gotten a naloxone kit; this percentage was higher for females (81%) than males (63%) ( P = ...
May 2018: North Carolina Medical Journal
https://www.readbyqxmd.com/read/29728845/the-perceptions-and-experiences-of-osteopathic-treatment-among-cancer-patients-in-palliative-care-a-qualitative-study
#17
Amie Steel, Colombe Tricou, Thomas Monsarrat, Murielle Ruer, Cécile Deslandes, Corinne Sisoix, Marilène Filbet
PURPOSE: This research aimed to explore the perceptions and experiences of cancer patients receiving osteopathic treatment as a complementary therapy when it is used in addition to conventional treatment for cancer pain. METHODS: This qualitative study employed semi structured interviews of cancer patients in a palliative care unit in Lyon, France, who received treatment from an osteopath alongside their conventional cancer treatment. We analysed data using grounded theory and qualitative methods...
May 4, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29726663/-trigger-effect-of-hmg-and-hcg-in-the-treatment-of-unexplainable-non-obstructive-azoospermia
#18
Hao-Rui Hu, Hong-Chuan Nie, Wei-Min Yang, Yuan Sun, Hui Huang, Fang-Gang Xie
Objective: To investigate whether the trigger effect of human menopausal gonadotropins (hMG) and human chorionic gonadotropins (hCG) attributes to the treatment of unexplainable non-obstructive azoospermia (NOA). METHODS: We retrospectively analyzed the clinical data about 282 cases of unexplainable NOA treated in the Maternity and Child Health Hospital of Guizhou Province from January 2010 to May 2017. All the patients underwent trigger treatment by intramuscular injection of hMG at 75 IU 3 times a week for 2 weeks, followed by hCG at 2 000 IU twice a week for another 2 weeks, and meanwhile took vitamin E, Levocarnitine and Tamoxifen as an adjunctive therapy...
September 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29720767/current-perspective-on-mdma-assisted-psychotherapy-for-posttraumatic-stress-disorder
#19
Sascha B Thal, Miriam J J Lommen
The present paper discusses the current literature with regard to substance-assisted psychotherapy with Methylenedioxymethamphetamine (MDMA) for posttraumatic stress disorder (PTSD). The aim of the paper is to give a comprehensive overview of the development from MDMA's early application in psychotherapy to its present and future role in the treatment of PTSD. It is further attempted to increase the attention for MDMA's therapeutic potential by providing a thorough depiction of the scientific evidence regarding its theorized mechanism of action and potential harms of its application in the clinical setting (e...
2018: Journal of Contemporary Psychotherapy
https://www.readbyqxmd.com/read/29715166/a-comprehensive-evidence-based-decision-algorithm-for-assisting-clinicians-and-patients-with-stable-ischemic-heart-disease-in-selecting-revascularization-strategy-in-multivessel-disease
#20
Lloyd W Klein, William S Weintraub
We propose an evidenced-based algorithm for the selection of revascularization strategy (coronary artery bypass surgery, percutaneous coronary intervention, or optimal medical therapy) to be applied in multivessel, non-acute coronary syndrome presentations. This algorithm provides a highly effective tool that is comprehensible to both physicians and patients.
May 2018: Journal of Invasive Cardiology
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