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https://www.readbyqxmd.com/read/28711971/innovative-technology-shows-impact-of-glycaemic-control-on-peripheral-retinal-vessels-in-adolescents-with-type-1-diabetes
#1
Valli Velayutham, Paul Z Benitez-Aguirre, Maria E Craig, Gerald Liew, Tien Y Wong, Alicia J Jenkins, Kim C Donaghue
AIMS/HYPOTHESIS: Retinal imaging enables non-invasive microvasculature assessment; however, only central retinal vessels have been studied in type 1 diabetes. Peripheral smaller vessels have a major haemodynamic role and may differ from central vessels in their response to the diabetic milieu. We hypothesise that diabetes has a greater impact on peripheral retinal vessels vs central vessels. METHODS: Retinal photographs from adolescents (n = 736; age 12-20 years) with type 1 diabetes were graded (Singapore I Vessel Assessment) with vessel calibres measured in the 'central zone' as central retinal arteriolar and venular equivalents (CRAE and CRVE, respectively) and the 'extended zone' as mean width of arterioles and venules (MWa and MWv, respectively)...
July 15, 2017: Diabetologia
https://www.readbyqxmd.com/read/28707652/thermal-ablation-in-the-management-of-adrenal-metastasis-originating-from-non-small-cell-lung-cancer-a-5-year-single-center-experience
#2
Evanthia I Botsa, Ioanna L Thanou, Aspasia T Papatheodoropoulou, Loukas I Thanos
BACKGROUND: Treatment of adrenal metastasis from lung carcinoma may prolong survival in the selected patients. However, not all patients can undergo surgery; thus, minimally invasive ablation procedures such as radiofrequency ablation (RFA) and microwave ablation (MWA) have gained acceptance as alternative treatment methods. This study summarized a 5-year single-center experience regarding the evaluation of safety and efficacy of computed tomography (CT)-guided thermal ablation in the management of adrenal metastasis originating from non-small cell lung cancer (NSCLC)...
July 13, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28701568/feasibility-and-efficacy-of-microwave-ablation-combined-with-iodine-125-seed-implantation-in-local-control-of-recurrent-retroperitoneal-liposarcomas-initial-clinical-experience
#3
Mingjian Lu, Wang Yao, Tao Zhang, Wenzhe Fan, Zhihui Zhong, Jiaping Li, Fujun Zhang
INTRODUCTION: The objective of the present study was to evaluate the feasibility, safety, and short-term efficacy of microwave ablation (MWA) combined with iodine-125 ((125)I) seed implantation in recurrent retroperitoneal liposarcomas (rRPLs). MATERIALS AND METHODS: From September 2012 to March 2015, 11 patients were enrolled in this prospective study. Eleven tumors (median, 9 cm; range, 5.5-12.5 cm) were treated with computerized tomography-guided MWA for 11 sessions and (125)I seed implantation for 18 sessions...
July 12, 2017: Oncologist
https://www.readbyqxmd.com/read/28693505/effects-of-radiofrequency-ablation-versus-other-ablating-techniques-on-hepatocellular-carcinomas-a-systematic-review-and-meta-analysis
#4
Wen Luo, Yunfei Zhang, Guangbin He, Ming Yu, Minjuan Zheng, Liwen Liu, Xiaodong Zhou
BACKGROUND: Percutaneous ablation has quickly arisen as one of the important alternative treatments for hepatocellular carcinoma (HCC). We aimed to compare the therapeutic effects of radiofrequency ablation (RFA) and other ablative techniques on HCCs. METHODS: Databases were searched to identify literature on complete tumor ablation (CTA), overall survival (OS), local tumor recurrence (LTR), and complications of RFA in the treatment of HCC, compared with those of microwave ablation (MWA), percutaneous ethanol injection (PEI), PEI plus RFA, cryoablation (CRA), laser ablation (LSA), and high-intensity focused ultrasound...
July 10, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28685457/physiological-effects-of-continuous-colored-light-exposure-on-mayer-wave-activity-in-cerebral-hemodynamics-a-functional-near-infrared-spectroscopy-fnirs-study
#5
A J Metz, S D Klein, F Scholkmann, U Wolf
We are increasingly exposed to colored light, but its impact on human physiology is not yet extensively investigated. In the present study we aimed to determine the effects of colored light on human cerebral Mayer wave activity (MWA). We measured oxy- ([O2Hb]), deoxy- ([HHb]), total hemoglobin ([tHb]) concentrations and tissue oxygen saturation (StO2) by functional near-infrared spectroscopy (fNIRS) in the left and right pre-frontal cortex (L-PFC, R-PFC) of 17 subjects (median age: 29 years, 6 women). In a randomized crossover design subjects were exposed to blue, red, green, and yellow LED light for 10 min...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28682866/efficacy-and-safety-of-ultrasound-guided-percutaneous-microwave-ablation-for-the-treatment-of-hepatic-alveolar-echinococcosis-a-preliminary-study
#6
Yangdan Cairang, Lingqiang Zhang, Bin Ren, Li Ren, Lizhao Hou, Haijiu Wang, Ying Zhou, Qingxi Zhang, Jun Shao, Haining Fan
The present study aims to assess the efficacy and safety of ultrasound-guided percutaneous microwave ablation (MWA) for hepatic alveolar echinococcosis (HAE) preliminarily.Seventeen patients diagnosed to HAE and treated with MWA (80 watts, 4 min) were retrospectively analyzed. The upper abdominal computed tomography (CT) was performed at 1, 6, 12 months after the MWA treatment. The complications were evaluated to assess the safety.The diameters of the lesions in the HAE patients ranged from 1.9 to 4.7 cm...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28681222/transarterial-chemoembolization-monotherapy-versus-combined-transarterial-chemoembolization-microwave-ablation-therapy-for-hepatocellular-carcinoma-tumors-%C3%A2-5%C3%A2-cm-a-propensity-analysis-at-a-single-center
#7
Qi-Feng Chen, Zhen-Yu Jia, Zheng-Qiang Yang, Wen-Long Fan, Hai-Bin Shi
PURPOSE: To compare effectiveness of transarterial chemoembolization (TACE) combined with microwave ablation (MWA; TACE-MWA) with TACE alone for treating hepatocellular carcinoma (HCC) tumors ≤5 cm. MATERIALS AND METHODS: We reviewed data of 244 patients treated for HCC by TACE-MWA or TACE from June 2014 to December 2015. Median follow-up period was 505 days (TACE-MWA group: 485 days; TACE group: 542 days). Patients were propensity score matched (1:2 ratio); outcomes of TACE-MWA and TACE groups were compared...
July 5, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28678572/percutaneous-image-guided-thermal-ablation-for-multifocal-renal-cell-carcinoma-10-year-experience-at-a-single-center
#8
Wenhui Zhou, Raul N Uppot, Adam S Feldman, Ronald S Arellano
OBJECTIVE: The objective of our study was to assess the technical success, safety, and oncologic and renal function outcomes of CT-guided percutaneous thermal ablation for synchronous multiple renal masses in a single session. MATERIALS AND METHODS: A retrospective analysis of 23 patients (16 men and 7 women; median age, 70 years) with biopsy-proven multifocal renal cell carcinoma (RCC) masses treated with radiofrequency ablation (RFA), cryoablation, or microwave ablation (MWA) was performed...
July 5, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28656458/a-genetic-risk-score-is-differentially-associated-with-migraine-with-and-without-aura
#9
Claudia Pisanu, Martin Preisig, Enrique Castelao, Jennifer Glaus, Giorgio Pistis, Alessio Squassina, Maria Del Zompo, Kathleen R Merikangas, Gérard Waeber, Peter Vollenweider, Jessica Mwinyi, Helgi B Schiöth
Although a number of migraine-associated single-nucleotide polymorphisms (SNP) with small effect size have been identified, little is known about the additive impact of these variants on migraine risk, frequency and severity. We investigated to what extent a genetic risk score (GRS) based on recently published, novel migraine-associated SNPs is associated with migraine prevalence, subtypes and severity in a large population-based sample. The sample comprised 446 subjects with migraine and 2511 controls from the CoLaus/PsyCoLaus study...
August 2017: Human Genetics
https://www.readbyqxmd.com/read/28648469/long-term-clinical-outcomes-following-radiofrequency-and-microwave-ablation-of-renal-cell-carcinoma-at-a-single-va-medical-center
#10
Salim E Abboud, Tanay Patel, Stephanie Soriano, Joseph Giesler, Nannette Alvarado, Preet Kang
PURPOSE: Microwave ablation (MWA) is a relatively newer treatment modality for treatment of renal cell carcinoma (RCC), and only a few small studies have examined the short- and long-term outcomes for MWA applied to renal tumors. The purpose of this retrospective review is to assess the initial experience including technical short- and long-term success rates of using radiofrequency ablation (RFA) and MWA for RCC at a single Veterans Affairs (VA) medical center. MATERIALS AND METHODS: Tumor characteristics were recorded using the R...
May 17, 2017: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/28643305/-interventional-therapy-of-colorectal-liver-metastasis
#11
Qi Zhang, Gaojun Teng
Colorectal liver metastasis (CRLM) is one of the most difficult and key points in the treatment of colorectal cancer. Approximately 50% to 60% of patients diagnosed as colorectal cancer develops metastasis, and 80% to 90% of CRLM is unresectable. Surgical resection is the first-line treatment for CRLM, while it is only suitable for about 15% patients. Systemic chemotherapy can prolong the survival of CRLM patients, however, a part of CRLM patients are resistant to chemotherapy. With the development of technology and the update of clinical evidence, individual therapy with target drugs and multidisciplinary treatment (MDT) have became a tendency, and minimally invasive interventional therapy has gained more acceptance in the MDT mode of the treatment for CRLM...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28641464/ultrasound-guided-hydrodissection-for-assisting-percutaneous-microwave-ablation-of-renal-cell-carcinomas-adjacent-to-intestinal-tracts-a-preliminary-clinical-study
#12
Zhigang Cheng, Xiaoling Yu, Zhiyu Han, Fangyi Liu, Jie Yu, Ping Liang
PURPOSE: To evaluate the safety and efficacy of the clinical application of hydrodissection under ultrasound (US) guidance for assisting percutaneous microwave ablation (MWA) for the treatment of renal cell carcinomas (RCCs) adjacent to the intestinal tract. MATERIALS AND METHODS: From April 2014 to December 2016, clinical data from 24 patients with 25 RCCs were retrospectively analysed. Percutaneous MWA under the assistance of US-guided hydrodissection were performed to treat RCCs with a mean maximal diameter of 3...
June 22, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28629577/comparison-of-ultrasonography-guided-percutaneous-microwave-ablation-for-subcapsular-and-nonsubcapsular-hepatocellular-carcinoma
#13
Fangyi Liu, Xiaoling Yu, Zhigang Cheng, Zhiyu Han, Ya Sun, Ping Liang, Fubo Zhou
PURPOSE: To compare the prognosis of subcapsular and nonsubcapsular hepatocellular carcinoma (HCC) after ultrasonography (US)-guided percutaneous microwave ablation (MWA). MATERIALS AND METHODS: From January 2012 to December 2015, 463 enrollment patients (382 men, 81 women; age range, 24-95 years) with a single HCC underwent US-guided percutaneous MWA. The patients were divided into two groups according to tumor location: subcapsular (n=224) and nonsubcapsular (n=239)...
June 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28611285/ultrasound-guided-percutaneous-microwave-ablation-of-benign-breast-lesions
#14
Jie Yu, Bao-Hua Chen, Jing Zhang, Han Wu, Yan Huang, Meng-Juan Mu, Ping Liang
The benign breast lesions (BBLs) share a high incidence for women and therapy methods with minimal invasion and better cosmetic outcome are thirsted for. In this study, 122 patients with 198 biopsy-proved BBLs were enrolled. Ultrasound (US)-guided microwave ablation (MWA) was performed with local anesthesia from November, 2013 to April, 2016. The mean longest tumor size assessed was 1.6±0.7 cm (ranging 0.7-4.9 cm). MWA was successfully performed in all cases including 85 lesions adjacent to the skin, pectoralis and areola...
May 23, 2017: Oncotarget
https://www.readbyqxmd.com/read/28599296/microwave-ablation-combined-with-egfr-tkis-versus-only-egfr-tkis-in-advanced-nsclc-patients-with-egfr-sensitive-mutations
#15
Zhigang Wei, Xin Ye, Xia Yang, Aimin Zheng, Guanghui Huang, Wenhong Li, Jiao Wang, Xiaoying Han, Min Meng, Yang Ni
We conducted this retrospective study to investigate whether microwave ablation (MWA) of primary tumor sites plus epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) could improve survival in advanced non small cell lung cancer (NSCLC) with EGFR mutations. MWA was conducted at the primary tumor sites, followed by EGFR-TKIs in the MWA plus EGFR-TKIs group. EGFR-TKIs were administered until disease progression or intolerable toxicity. The primary endpoint was progression-free survival (PFS); secondary endpoints were overall survival (OS) and objective response rate (ORR)...
May 23, 2017: Oncotarget
https://www.readbyqxmd.com/read/28595851/delineation-of-post-procedure-ablation-regions-with-electrode-displacement-elastography-with-a-comparison-to-acoustic-radiation-force-impulse-imaging
#16
Wenjun Yang, Tomy Varghese, Timothy Ziemlewicz, Marci Alexander, Meghan Lubner, James Louis Hinshaw, Shane Wells, Fred T Lee
We compared a quasi-static ultrasound elastography technique, referred to as electrode displacement elastography (EDE), with acoustic radiation force impulse imaging (ARFI) for monitoring microwave ablation (MWA) procedures on patients diagnosed with liver neoplasms. Forty-nine patients recruited to this study underwent EDE and ARFI with a Siemens Acuson S2000 system after an MWA procedure. On the basis of visualization results from two observers, the ablated region in ARFI images was recognizable on 20 patients on average in conjunction with B-mode imaging, whereas delineable ablation boundaries could be generated on 4 patients on average...
September 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28545682/percutaneous-microwave-ablation-of-renal-cancers-under-ct-guidance-safety-and-efficacy-with-a-2-year-follow-up
#17
P Chan, S Vélasco, G Vesselle, S Boucebci, G Herpe, B Debaene, P Ingrand, J Irani, J-P Tasu
AIM: To evaluate the safety and efficiency of percutaneous microwave ablation (MWA) of renal cell carcinomas (RCC) carried out under computed tomography (CT) guidance. MATERIALS AND METHODS: A retrospective study was performed on RCC that was either histologically proven or diagnosed at imaging (Bosniak IV cyst) and treated by MWA under general anaesthesia with CT guidance. Indications for percutaneous ablation were based on the American Urological Association recommendations...
May 22, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28543540/computational-modeling-of-915-mhz-microwave-ablation-comparative-assessment-of-temperature-dependent-tissue-dielectric-models
#18
Garron Deshazer, Mark Hagmann, Derek Merck, Jan Sebek, Kent B Moore, Punit Prakash
PURPOSE: The objective of this study is to develop a computational model for simulating 915 MHz microwave ablation (MWA), and verify the simulation predictions of transient temperature profiles against experimental measurements. Due to the limited experimental data characterizing temperature-dependent changes of tissue dielectric properties at 915 MHz, we comparatively assess two temperature dependent approaches of modeling of dielectric properties: model A- piecewise linear temperature dependencies based on existing, but limited, experimental data, and model B- similar to model A, but augmented with linear decrease in electrical conductivity above 95 °C, as guided by our experimental measurements...
May 23, 2017: Medical Physics
https://www.readbyqxmd.com/read/28540822/clinical-and-survival-outcomes-of-percutaneous-microwave-ablation-for-intrahepatic-cholangiocarcinoma
#19
Kai Zhang, Jie Yu, Xiaoling Yu, Zhiyu Han, Zhigang Cheng, Fangyi Liu, Ping Liang
OBJECTIVE: To evaluate the outcomes of percutaneous microwave ablation (MWA) and explore the prognostic factors for the survival of patients with intrahepatic cholangiocarcinoma (ICC). METHODS: A total of 107 patients (age: mean 58.0 years, range 15-85 years) with 171 ICCs (maximum size ≤5 cm, tumour number per patient ≤3) who underwent MWA for ICC during January 2009 to February 2016 were selected, and their clinical and pathological data were collected and reviewed...
May 19, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28540791/ablation-therapy-of-non-colorectal-cancer-lung-metastases-retrospective-analysis-of-tumour-response-post-laser-induced-interstitial-thermotherapy-litt-radiofrequency-ablation-rfa-and-microwave-ablation-mwa
#20
Nour-Eldin A Nour-Eldin, Sybille Exner, Mohammed Al-Subhi, Nagy N N Naguib, Benjamin Kaltenbach, Andrei Roman, Thomas J Vogl
PURPOSE: To retrospectively compare the local tumour response and survival rates in patients with non-colorectal cancer lung metastases post-ablation therapy using laser-induced thermotherapy (LITT), radiofrequency ablation (RFA) and microwave ablation (MWA). MATERIAL AND METHODS: Retrospective analysis of 175 computed tomography (CT)-guided ablation sessions performed on 109 patients (43 males and 66 females, mean age: 56.6 years). Seventeen patients with 22 lesions underwent LITT treatment (tumour size: 1...
April 3, 2017: International Journal of Hyperthermia
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