Read by QxMD icon Read


Michael N Cohen, Samuel K Houston, Alexander Juhn, Allen C Ho, Carl D Regillo, James Vander, Allen Chiang
OBJECTIVE: To report short-term visual and anatomic outcomes of patients who were switched to aflibercept for persistent macular edema associated with central retinal vein occlusion (CRVO). METHODS: Retrospective, consecutive, interventional case series of 17 patients with persistent macular edema secondary to CRVO (defined as intraretinal edema and either <50 µm reduction in central foveal thickness [CFT] or worsening or no improvement in visual acuity [VA] compared to baseline) despite anti-VEGF treatment who were switched to aflibercept treatment...
October 2016: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
Aneesh Mohimen, Santhosh Kumar, E R Jayadevan
PURPOSE: To describe a rare clinical entity of intra-osseous skull base arterio-venous fistula managed with transvenous fistula embolization. CASE DETAILS: 57 year old lady presented with complaints of headache and episodic tinnitus with progressive left sided visual deterioration. Cross sectional imaging of the head revealed multiple vascular channels in the sphenoid bone and in bilateral masticator spaces. Catheter angiography showed presence of a large osseous arterio-venous fistula (AVF) epicentered in the body of sphenoid and left pterygoid plates with arterial feeders from bilateral external carotid arteries and venous drainage...
October 11, 2016: World Neurosurgery
Santhosh Saklecha
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
Michael B Powner, Dawn A Sim, Meidong Zhu, João Nobre-Cardoso, Ryan Jones, Adil Syed, Andrew A Chang, Pearse A Keane, Adnan Tufail, Catherine A Egan, Marcus Fruttiger
Purpose: Retinal ischemia has been traditionally assessed by fluorescein angiography, visualizing perfused vessels. However, this method does not provide any information about nonperfused vessels, and although it is often assumed that vessels in ischemic areas regress, we know little about how nonperfused retinal vessels change over time. Here, we aim to learn more about the long-term fate of nonperfused vessels in the retinal vasculature. Methods: Optical coherence tomography (OCT) was used to visualize perfusion as well as structural properties of the retinal vasculature in patients suffering from retinal vascular occlusions...
September 1, 2016: Investigative Ophthalmology & Visual Science
Yoshitsugu Saishin, Yuka Ito, Masato Fujikawa, Tomoko Sawada, Masahito Ohji
PURPOSE: We compared the efficacy of bimonthly intravitreal injections of ranibizumab (IVR) with that of bimonthly intravitreal injections of aflibercept (IVA) in two prospective, consecutive groups of patients with macular edema (ME) secondary to central retinal vein occlusion (CRVO). PATIENTS AND METHODS: Eyes with ME after CRVO received either bimonthly IVR (ranibizumab group; n = 13) or IVA (aflibercept group; n = 13) injections and were followed monthly for 6 months...
September 22, 2016: Japanese Journal of Ophthalmology
Kai Januschowski, Nicolas Feltgen, Amelie Pielen, Bernhard Spitzer, Matus Rehak, Georg Spital, Spyridon Dimopoulos, Carsten H Meyer, Gesine B Szurman
PURPOSE: Vision loss in central retinal vein occlusion (CRVO) is mostly caused by macular edema (ME) and can be treated with intravitreal bevacizumab injections. The goal of this study was to identify predictive factors for improvement in visual acuity. METHODS: Three hundred and sixteen eyes of six centres having received intravitreal bevacizumab for ME due to CRVO were enrolled in this multicentre, retrospective, interventional case series. The follow-up time was 24 to 48 weeks...
September 8, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Nopasak Phasukkijwatana, Mansour Rahimi, Nicholas Iafe, David Sarraf
A 21-year-old healthy female presented with acute-onset vision loss in the left eye. Multimodal imaging, including fundus photography and fluorescein angiography, was unremarkable. En face optical coherence tomography (OCT) demonstrated paracentral acute middle maculopathy (PAMM) lesions in a perivenular fern-like pattern leading to the diagnosis of central retinal vein occlusion (CRVO). En face OCT can be an important modality to identify the distribution of abnormalities of the middle retina such as PAMM...
September 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
Jay Chhablani, Michael Stewart, Remya Paulose, Roberto Gallego-Pinazo, Rosa Dolz-Marco
PURPOSE: To report the ocular findings, systemic hematologic parameters, and treatment outcomes of patients with recurrent central retinal vein occlusions (CRVO). METHODS: A retrospective analysis of eyes that developed recurrent CRVO was performed. Key exclusion criteria were follow-up of less than six months after the recurrence, incomplete documentation, and recurrent macular edema in an eye with a CRVO but without evidence of increased superficial hemorrhage or disc edema (recurrent CRVO)...
September 9, 2016: Seminars in Ophthalmology
Sandra Rilvén, Thomas Lee Torp, Jakob Grauslund
The retinal oximeter is a new tool for non-invasive measurement of retinal oxygen saturation in humans. Several studies have investigated the associations between retinal oxygen saturation and retinal diseases. In the present systematic review, we examine whether there are associations between retinal oxygen saturation and retinal ischaemic diseases. We used PubMed and Embase to search for retinal oxygen saturation and retinal ischaemic diseases. Three separate searches identified a total of 79 publications...
September 1, 2016: Acta Ophthalmologica
Yaoyao Sun, Yong Liang, Peng Zhou, Huijuan Wu, Xianru Hou, Zeqin Ren, Xiaoxin Li, Mingwei Zhao
BACKGROUND: To present a comprehensive approach for the management of patients with neovascular glaucoma (NVG) aiming to preserve visual function and complement pan-retinal photocoagulation (PRP) by anti-vascular endothelial growth factor (anti-VEGF) treatment and anti-glaucoma surgery. METHODS: This study includes a prospective, interventional case series. A process flow chart for NVG management was designed. Totally 50 patients (51 eyes) with NVG were included...
August 30, 2016: BMC Ophthalmology
Nadim Rayess, Ehsan Rahimy, Gui-Shuang Ying, Maria Pefkianaki, Jason Franklin, Carl D Regillo, Allen C Ho, Jason Hsu
PURPOSE: To evaluate the association between initial subfoveal choroidal thickness and response to anti-vascular endothelial growth factor (anti-VEGF) therapy in central retinal vein occlusion (CRVO) eyes. DESIGN: Retrospective cohort study. METHODS: 43 eyes from 42 patients with treatment-naïve CRVO. All patients included were treated with a standard algorithm of 3 monthly anti-VEGF injections. Serial enhanced depth imaging optical coherence tomography scans were used to measure subfoveal choroidal thickness and central macular thickness (CMT)...
August 24, 2016: American Journal of Ophthalmology
Subina Narang, Panchmi Gupta, Anuj Sharma, Sunandan Sood, Anshu Palta, Shilpa Goyal
Central retinal vein occlusion (CRVO) is a common pathology of the retinal vasculature. Patients with CRVO usually present with a drop in visual acuity. The condition bears no specific therapy; treatment is aimed at the management of potentially blinding complications, of which there are many. With majority of cases being unilateral, bilateral CRVO is usually associated with an underlying systemic illness such as a hyperviscosity syndrome. Here, we present a case of a patient, who presented with a bilateral drop in vision diagnosed as bilateral CRVO on ophthalmic evaluation...
July 2016: Middle East African Journal of Ophthalmology
Karen M Wai, Mehnaz Khan, Sunil Srivastava, Aleksandra Rachitskaya, Fabiana Q Silva, Ryan Deasy, Andrew P Schachat, Amy Babiuch, Justis P Ehlers, Peter K Kaiser, Alex Yuan, Rishi P Singh
AIM: To determine the impact of initial visual acuity (VA) on anti-vascular endothelial growth factor (VEGF) treatment outcomes in patients with macular oedema secondary to retinal vein occlusions in routine clinical practice. METHODS: A retrospective study was conducted at a single academic institution to identify 177 treatment naïve patients with macular oedema secondary to branch retinal vein occlusion (BRVO), hemiretinal vein occlusion (HRVO) and central retinal vein occlusion (CRVO) treated with intravitreal anti-VEGFs...
August 8, 2016: British Journal of Ophthalmology
Nicole Eter, Andreas Mohr, Joachim Wachtlin, Nicolas Feltgen, Andrew Shirlaw, Richard Leaback
PURPOSE: To evaluate the relationship between duration of macular edema associated with retinal vein occlusion (RVO) and the achievement of vision gain in patients receiving dexamethasone intravitreal implant (DEX implant) in real-world clinical practice, and to define patterns of use of DEX implant and its efficacy and safety in the treatment of patients with RVO in clinical practice. METHODS: This prospective, open-label, multicenter, 6-month observational phase IV study conducted at 70 sites in Germany enrolled patients diagnosed with macular edema following branch or central RVO (BRVO, CRVO) who were given DEX implant...
July 26, 2016: Graefe's Archive for Clinical and Experimental Ophthalmology
Ingrid U Scott, Paul C VanVeldhuisen, Michael S Ip, Barbara A Blodi, Neal L Oden, Maria Figueroa
PURPOSE: To investigate recruitment rates of patients with central retinal vein occlusion (CRVO) into phase III clinical trials evaluating intravitreal pharmacotherapy for treatment of macular edema in the United States, describe recruitment techniques in the Study of COmparative Treatments for REtinal Vein Occlusion 2 (SCORE2), and assess which SCORE2 recruitment techniques were most useful to principal investigators and clinical coordinators. DESIGN: Retrospective survey within a randomized clinical trial...
October 2016: American Journal of Ophthalmology
Mehreen Adhi, Marco A Bonini Filho, Ricardo N Louzada, Laura Kuehlewein, Talisa E de Carlo, Caroline R Baumal, Andre J Witkin, Srinivas R Sadda, David Sarraf, Elias Reichel, Jay S Duker, Nadia K Waheed
PURPOSE: To evaluate the perifoveolar retinal capillary network at different depths and to quantify the foveal avascular zone (FAZ) in eyes with retinal vein occlusion (RVO) compared with their fellow eyes and healthy controls using spectral-domain optical coherence tomography angiography (SD-OCTA). METHODS: We prospectively recruited 23 patients with RVO including 15 eyes with central RVO (CRVO) and 8 eyes with branch RVO (BRVO), their fellow eyes, and 8 age-matched healthy controls (8 eyes) for imaging on prototype OCTA software within RTVue-XR Avanti...
July 1, 2016: Investigative Ophthalmology & Visual Science
Alexander Kahjun Soon, Paulo Ricardo Chaves de Oliveira, David Robert Chow
Central retinal vein occlusion (CRVO) is one of the most common retinal vascular disorders. Intense exercise associated CRVO have been described in otherwise healthy young patients. We describe a case of a young male ultramarathoner who presented with a CRVO, presumably associated with dehydration, making part of a marathon runner's retinopathy. Resolution of macular edema and subretinal fluid, with visual acuity improvement, was observed after 3 monthly injections of ranibizumab. Our case suggests that dehydration could be involved in the mechanism of CRVO in healthy young patients and ranibizumab may be an effective treatment option for marathon runner's retinopathy...
2016: Case Reports in Ophthalmological Medicine
Sibel Doguizi, Mehmet Ali Sekeroglu, Mustafa Alpaslan Anayol, Pelin Yilmazbas
Purpose. To report a young male with unilateral central retinal vein occlusion (CRVO) associated with cryoglobulinemia. Case Presentation. A 33-year-old male without any known systemic or ocular disorder was admitted to our clinic with a complaint of visual loss for three days in his left eye. Based on the clinical, laboratory, and ophthalmological assessments, we diagnosed this case as type III mixed cryoglobulinemia with unilateral CRVO with macular edema. For treatment, two intravitreal ranibizumab injections were administered monthly and oral prednisone (64 mg/day) was begun...
2016: Case Reports in Ophthalmological Medicine
Yijun Hu, Alp Atik, Honghua Yu, Tao Li, Boyong Zhang, Dongli Li, Ning Cai, Yang Yu, Jing Chen, Guodong Li, Ling Yuan
PURPOSE: To investigate the serum heparanase concentration and heparanase activity of the patients with central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO). METHODS: This prospective study included 23 CRVO patients, 13 BRVO patients and 28 control subjects. Serum heparanase concentration was measured by ELISA. Serum heparanase activity was determined using a heparan degrading enzyme assay kit (Mountain View, CA, USA). Multivariate logistic regression was used to adjust for the possible confounding factors when comparing the difference in serum heparanase concentration and activity between patients with RVO and control subjects...
July 15, 2016: Acta Ophthalmologica
Sandra Rezar-Dreindl, Katharina Eibenberger, Andreas Pollreisz, Wolf Bühl, Michael Georgopoulos, Christoph Krall, Roman Dunavölgyi, Günther Weigert, Maria-Elisabeth Kroh, Ursula Schmidt-Erfurth, Stefan Sacu
PURPOSE: To investigate the influence of intravitreal dexamethasone implant on inflammatory and angiogenic cytokine levels in the aqueous of patients with retinal vein occlusion (RVO). METHODS: Forty eyes of 40 consecutive patients with macular oedema (ME) due to branch and central retinal vein occlusion (BRVO/CRVO) were treated with an intravitreal dexamethasone implant (Ozurdex(®) ) at baseline and evaluated until month 6. Retreatment was performed in case of recurrent ME earliest 4 months after the baseline treatment...
July 15, 2016: Acta Ophthalmologica
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"