Olatunji Sunday Yinka, Ogunnaike Philip Olubunmi, Abijo Ayodeji Zabdiel, Owolabi Joshua Oladele, Adelodun Stephen Taiye, Adeoye Ayodele, Fasesan Oluwatoyin Adetutu, Olanrewaju John Afees, Adegbite Ademola Kayode
BACKGROUND: Despite widespread concerns about its possible side effects, notably on the prefrontal cortex (PFC), which mediates cognitive processes, the use of Cannabis sativa as a medicinal and recreational drug is expanding exponentially. This study evaluated possible behavioral alterations, neurotransmitter levels, histological, and immunohistochemical changes in the PFC of Wistar rats exposed to Cannabis sativa . PURPOSE: To evaluate the effect of graded doses of Cannabis sativa on the PFC using behavioural, histological, and immunohistochemical approaches...
April 2023: Annals of Neurosciences