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cvd in 40 year old and below

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https://www.readbyqxmd.com/read/27611006/antibodies-against-phosphorylcholine-among-new-guineans-compared-to-swedes-an-aspect-of-the-hygiene-missing-old-friends-hypothesis
#1
Johan Frostegård, WenJing Tao, Lennart Råstam, Ulf Lindblad, Staffan Lindeberg
BACKGROUND: We here study antibodies against phosphorylcholine (anti-PC) which we reported to be inversely associated with atherosclerosis, cardiovascular disease (CVD), and autoimmune conditions. In previous studies, we determined that this inverse association is more pronounced at low levels with high risk and at high levels, with decreased risk. We compare individuals from Kitava, New Guinea (with low risk of these conditions), with Swedish controls. METHODS: We studied a group of 178 individuals from Kitava (age 20-86), and compared those above age 40 (n = 108) with a group of age- and sex-matched individuals from a population based cohort in Sweden (n = 108)...
September 9, 2016: Immunological Investigations
https://www.readbyqxmd.com/read/26112693/genes-involved-in-the-pathogenesis-of-premature-ovarian-insufficiency
#2
C Orlandini, C Regini, F L Vellucci, F Petraglia, S Luisi
Premature ovarian insufficiency (POI) is defined by the presence of primary or secondary amenorrhea, for at least 4 months, before the age of 40 years associated with follicle stimulating homone levels in menopausal range, exciding 40 UI/L. The diagnosis is confirmed by two blood sample at least 1 month to measure the level of FSH (over 40 UI/L) and level of estradiol (below 50 pmol/L). Ovarian follicular dysfunction and/or depletion of functional primordial follicles characterized this pathology. Abnormal bleeding patterns also include oligomenrrhea and polimenorrhea; because of these irregular menstrual cycles during adolescence, diagnosis could be difficult in young women...
October 2015: Minerva Ginecologica
https://www.readbyqxmd.com/read/25172228/higher-dietary-salt-intake-is-associated-with-microalbuminuria-but-not-with-retinopathy-in-individuals-with-type-1-diabetes-the-eurodiab-prospective-complications-study
#3
Lian Engelen, Sabita S Soedamah-Muthu, Johanna M Geleijnse, Monika Toeller, Nish Chaturvedi, John H Fuller, Casper G Schalkwijk, Coen D A Stehouwer
AIMS/HYPOTHESIS: High dietary salt intake has been associated with elevated BP and may also have a deleterious effect on microvascular complications. We studied the cross-sectional associations between dietary salt intake (estimated from 24 h urinary sodium excretion) and urinary potassium excretion on the one hand, and the prevalence of microvascular complications on the other, in individuals with type 1 diabetes. METHODS: We measured sodium and potassium concentrations in two 24 h urine samples in 1,212 individuals with type 1 diabetes (40 ± 10 years old, 51% men) who participated in the EURODIAB Prospective Complications Study...
November 2014: Diabetologia
https://www.readbyqxmd.com/read/23995547/cardiovascular-effects-of-abduction-shoulder-sling-in-elderly-patients-is-it-really-safe
#4
Kerem Canbora, Ozkan Kose, Ufuk Gurkan, Atilla Polat, Sevki Erdem, Ugur Haklar
OBJECTIVE: The purpose of the prospective study is to investigate the cardiovascular effects of abduction shoulder sling (ASS) in elderly patients who underwent rotator cuff surgery. METHODS: The study included 49 consecutive patients older than 50 years (mean 59.3 ± 8.2 years) who underwent arthroscopic rotator cuff repair surgery and used ASS in postoperative period. All cases underwent Holter electrocardiographic monitoring before (24 h) and after (48 h) the operation...
November 2013: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/23074460/bariatric-surgery-an-evidence-based-analysis
#5
(no author information available yet)
OBJECTIVE: To conduct an evidence-based analysis of the effectiveness and cost-effectiveness of bariatric surgery. BACKGROUND: Obesity is defined as a body mass index (BMI) of at last 30 kg/m(2).() Morbid obesity is defined as a BMI of at least 40 kg/m(2) or at least 35 kg/m(2) with comorbid conditions. Comorbid conditions associated with obesity include diabetes, hypertension, dyslipidemias, obstructive sleep apnea, weight-related arthropathies, and stress urinary incontinence...
2005: Ontario Health Technology Assessment Series
https://www.readbyqxmd.com/read/22317161/occupational-stress-working-condition-and-nutritional-status-of-military-police-officers
#6
Angela Maria C Santana, Josiane Keila V Gomes, Dione De Marchi, Yassana M Girondoli, Lina E F P de Lima Rosado, Gilberto Paixão Rosado, Isabel Maria de Andrade
This study aimed to investigate the relationship between stress, working conditions and the nutritional status of 53 military police officers in a Southeast city of Brazil. In order to evaluate the symptomatology and the stress phase, the Inventory of Stress Symptoms Lipp for Adults - ISSL was utilized. The assessment of the working conditions was performed by means of socio-demographic questionnaire, direct observation and interviews. The nutritional and health conditions were assessed through anthropometric measures, biochemical tests, blood pressure measurements and cardiovascular disease risk calculator...
2012: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/21778651/-epidemiological-study-on-hba1c-level-below-6-1-among-community-residents-and-follow-up-study-of-hba1c-level-clinical-significance-of-health-examination-japan-in-the-aged-members-from-the-view-point-of-glucose-metabolism
#7
Shunji Imanaka
AIM: This study is to investigate whether the set point of HbA1c being 5.2% or more is too strict a line to be drawn by Tokutei-kensin (Health Examination for metabolic syndrome in Japan) on people 65 years old or more from the view point of glucose metabolism. METHODS: Samples were out-patients of the community clinic and community residents from the jurisdiction of the community clinic. (1) Epidemiological data on those who were in their 50s, 60s and 70s with HbA1c level between 5...
2011: Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
https://www.readbyqxmd.com/read/20675397/cardiovascular-and-metabolic-risk-profiles-in-young-and-old-patients-with-type-2-diabetes
#8
W Gunathilake, S Song, S Sridharan, D J Fernando, I Idris
BACKGROUND: Young patients (aged < 40 years) with type 2 diabetes (T2D) have a high lifetime risk of developing cardiovascular disease (CVD). However, little is known about the CVD risk profile of this cohort in the UK primary care setting. AIM: To determine CVD risk profile of young patients with T2D without CVD compared to older (aged >40 years) subjects. DESIGN: A cross-sectional study using The Health Improvement Network (THIN) database, which contains anonymized patient information from more than 300 general practices throughout England and Wales...
November 2010: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/20014994/cost-effectiveness-analysis-of-the-use-of-a-high-intensity-statin-compared-to-a-low-intensity-statin-in-the-management-of-patients-with-familial-hypercholesterolaemia
#9
COMPARATIVE STUDY
L Nherera, N W Calvert, K Demott, S E Humphries, H A W Neil, R Minhas, M Thorogood
OBJECTIVES: To estimate, using probabilistic decision-analytic modelling techniques, the cost effectiveness of treating familial hypercholesterolaemia (FH) patients with high-intensity statins compared to treatment with low-intensity statins. For the purpose of this economic analysis, and based on their known differences, statins were categorised as high intensity if they produce greater LDL-cholesterol reductions than simvastatin 40 mg (e.g., simvastatin 80 mg and appropriate doses of atorvastatin and rosuvastatin or combination of statins + ezetimibe)...
March 2010: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/18476574/-baseline-study-and-analysis-on-a-stroke-risk-factor-related-cohort-in-fengxian-county-of-shanghai
#10
Yan Wang, Jiu-Yi Huang, Yi-Feng Cao, Ji-Ping Guo, Yong-Ju Yang, Xue-Hai Yu, Feng-Ying Shen, Gui-Qing Wang
OBJECTIVE: To explore the exposed level of stroke risk factors in Fengxian county of Shanghai and the relationships between risk factors and stroke. METHODS: Community based populations including 10,565 individuals aged 40 years old and over were cluster sampled from Fengxian county in 2003 or 2004. Status of exposure on common risk factors such as hypertension, cardiovascular disease, diabetes, family history of stroke, cigarette smoking, alcohol intake were gathered while cerebral vascular hemodynamic index (CVHI) was examined, with CVHI score below 75 points as abnormal...
December 2007: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/17699531/randomised-controlled-trial-of-home-based-walking-programmes-at-and-below-current-recommended-levels-of-exercise-in-sedentary-adults
#11
RANDOMIZED CONTROLLED TRIAL
Mark A Tully, Margaret E Cupples, Nigel D Hart, Jane McEneny, Kieran J McGlade, Wai-Sun Chan, Ian S Young
OBJECTIVES: To determine, using unsupervised walking programmes, the effects of exercise at a level lower than currently recommended to improve cardiovascular risk factors and functional capacity. DESIGN: 12 week randomised controlled trial. SETTING: Northern Ireland Civil Service; home-based walking. PARTICIPANTS: 106 healthy, sedentary 40 to 61 year old adults of both sexes. INTERVENTIONS: Participants were randomly allocated to a walking programme (30 minutes brisk walking three days a week (n = 44) or five days a week (n = 42)) or a control group (n = 20)...
September 2007: Journal of Epidemiology and Community Health
https://www.readbyqxmd.com/read/17221106/aspirin-therapy-is-still-underutilized-among-patients-with-type-2-diabetes
#12
MULTICENTER STUDY
Cristiane B Leitão, Ana L Krahe, Gustavo B Nabinger, Paula X Picon, Miriam Pecis, Lérida M Zaslavsky, Jorge L Gross, Luis H Canani
The daily use of aspirin in patients with type 2 diabetes mellitus (DM2) reduces significantly cardiovascular events (CVE). In the absence of contraindications, American Diabetes Association (ADA) recommends the use of aspirin to all DM2 patients older than 40 years of age. To evaluate aspirin use among 636 out patients with DM2 who participate in a regional multicenter study in Southern Brazil, a standard questionnaire was used. Patients also underwent a physical examination and laboratorial tests. All patients were older than 40 years (mean 58 +/- 11 years old; 42% male) and by ADA guidelines most of them should be using aspirin...
December 2006: Arquivos Brasileiros de Endocrinologia e Metabologia
https://www.readbyqxmd.com/read/16297438/human-health-implications-of-environmental-contaminants-in-arctic-canada-a-review
#13
REVIEW
J Van Oostdam, S G Donaldson, M Feeley, D Arnold, P Ayotte, G Bondy, L Chan, E Dewaily, C M Furgal, H Kuhnlein, E Loring, G Muckle, E Myles, O Receveur, B Tracy, U Gill, S Kalhok
The objectives of this paper are to: assess the impact of exposure to current levels of environmental contaminants in the Canadian Arctic on human health; identify the data and knowledge gaps that need to be filled by future human health research and monitoring; examine how these issues have changed since our first assessment [Van Oostdam, J., Gilman, A., Dewailly, E., Usher, P., Wheatley, B., Kuhnlein, H. et al., 1999. Human health implications of environmental contaminants in Arctic Canada: a review. Sci Total Environ 230, 1-82]...
December 1, 2005: Science of the Total Environment
https://www.readbyqxmd.com/read/12493255/age-specific-relevance-of-usual-blood-pressure-to-vascular-mortality-a-meta-analysis-of-individual-data-for-one-million-adults-in-61-prospective-studies
#14
Sarah Lewington, Robert Clarke, Nawab Qizilbash, Richard Peto, Rory Collins
BACKGROUND: The age-specific relevance of blood pressure to cause-specific mortality is best assessed by collaborative meta-analysis of individual participant data from the separate prospective studies. METHODS: Information was obtained on each of one million adults with no previous vascular disease recorded at baseline in 61 prospective observational studies of blood pressure and mortality. During 12.7 million person-years at risk, there were about 56000 vascular deaths (12000 stroke, 34000 ischaemic heart disease [IHD], 10000 other vascular) and 66000 other deaths at ages 40-89 years...
December 14, 2002: Lancet
https://www.readbyqxmd.com/read/11527517/underreporting-of-energy-intake-in-repeated-24-hour-recalls-related-to-gender-age-weight-status-day-of-interview-educational-level-reported-food-intake-smoking-habits-and-area-of-living
#15
G Johansson, A Wikman, A M Ahrén, G Hallmans, I Johansson
OBJECTIVE: The aims of the present study were (1) to evaluate the degree to which underreporting of energy intake by repeated 24-hour recalls was related to gender, age, weight status, day of interview, educational level, smoking habits and area of living, and (2) to compare the dietary characteristics of underreporters with those of others. DESIGN: Cross-sectional study. Ten 24-hour recalls were performed during a one-year period. SETTING: The Västerbotten intervention programme of cardiovascular disease and diabetes in Northern Sweden...
August 2001: Public Health Nutrition
https://www.readbyqxmd.com/read/11155141/cardiovascular-autonomic-neuropathy-in-insulin-dependent-diabetes-mellitus-prevalence-and-estimated-risk-of-coronary-heart-disease-in-the-general-population
#16
COMPARATIVE STUDY
O May, H Arildsen, E M Damsgaard, H Mickley
OBJECTIVES: The aim of the study was to estimate the prevalence of cardiovascular autonomic neuropathy (CAN) in Type 1 diabetes mellitus in the general population and to assess the relationship between CAN and risk of future coronary heart disease (CHD). METHODS: The Type 1 diabetes mellitus population in the municipality of Horsens, Denmark, was delineated by the prescription method and a random sample of 120 diabetics aged 40-75 years was recruited. Type 1 diabetes mellitus was registered if fasting C-peptide was below 0...
December 2000: Journal of Internal Medicine
https://www.readbyqxmd.com/read/10657565/distribution-of-ultrasonographically-assessed-dimensions-of-common-carotid-arteries-in-healthy-adults-of-both-sexes
#17
N Denarié, J Gariepy, G Chironi, M Massonneau, F Laskri, J Salomon, J Levenson, A Simon
Our objective was to provide a description of 'normal' carotid artery dimensions which are increasingly used for detecting early atherosclerosis and predicting clinical complications. Far wall intima-media thickness (IMT), lumen diameter and cross-sectional area intima-media thickness (CSA-IMT) were measured on 1 cm-distal common carotid artery segments on both sides by B-mode ultrasound, using an automated computerized edge-detection program, in 133 men and 216 women aged 17-65 years and free from cardiovascular disease and traditional risk factors...
February 2000: Atherosclerosis
https://www.readbyqxmd.com/read/7455106/an-assessment-of-the-contribution-of-chest-radiography-in-outpatients-with-acute-chest-complaints-a-prospective-study
#18
B R Benacerraf, T C McLoud, J T Rhea, V Tritschler, P Libby
The contribution of chest radiography to diagnosis was assessed in 1,102 consecutive patients with chest complaints at the Emergency Ward and Ambulatory Screening Clinic of a large hospital. The goal of this prospective study was to identify selective indications for chest radiography in this population with relation to the patient's age, the symptoms, and the results of physical examination. Although in patients over 40 years old chest symptoms are a sufficient indication for chest radiography, 96% of the patients below age 40 had a normal physical examination of the chest, no hemoptysis, and no acute radiographic abnormalities...
February 1981: Radiology
https://www.readbyqxmd.com/read/6545039/hypertension-in-elderly-people-in-a-swedish-primary-care-district
#19
L Lindholm, B Scherstén, T Thulin
In a retrospective study, 124 hypertensives aged 60-69 years, and taken care of by primary health care, were compared with 124 age and sex matched controls with regard to blood pressure, body mass index, smoking and alcohol habits as well as cardiovascular diseases. Blood pressure, mean +/- SEM (mm Hg) was reduced by 37/24 in males and 40/24 in females. Drug treatment was given to 93 per cent of the patients. Our goal of treatment - blood pressure 180/100 or below - was obtained in 75 per cent of the patients...
1983: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/3408021/cardiac-alterations-in-ankylosing-spondylitis
#20
M G Alves, J Espirito-Santo, M V Queiroz, H Madeira, E Macieira-Coelho
Forty patients, 30 men and 10 women with an average age of 38.47 +/- 11.07 years, suffering from ankylosing spondylitis and attending a Rheumatology Outpatient Clinic, were evaluated for cardiovascular involvement. The evaluation was based on patients' clinical observation, electrocardiography, echocardiography, and chest x-ray. More than a simple review, this study was undertaken with the aim of arriving at a better clinical definition of the cardiovascular manifestations found in ankylosing spondylitis. In fact, of the 40 patients, 8 (20%) had systemic hypertension for which an explanation could not be found, 4 of whom were less than forty-five years old; the echocardiogram showed mitral valve prolapse in 4 patients (10%), 2 of them with a systolic murmur and other 2 with a protosystolic click on auscultation...
July 1988: Angiology
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