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Wei Yuan, Guining Lu, Yingying Xie, Kaibo Huang, Rui Wang, Hua Yin, Zhi Dang
In this study, we have investigated the photolysis of 2,4,4'-tribromophenylphenyl ether (BDE-28) in Triton X-100 (TX-100) solutions, and discussed the effect of anthraquinone-2,6-disulfonate (AQDS) on the photolysis of BDE-28. The effect of TX-100 on the photolysis of BDE-28 was mainly related to the concentration of TX-100. The fastest photolysis of BDE-28 was at 500 mg L(-1) of the TX-100 solution, and the corresponding photolysis rate constant was 0.12 min(-1). The direct photolysis rate of BDE-28 decreased from 0...
April 24, 2017: Photochemical & Photobiological Sciences
Hiroshi Nakano, Hirofumi Sato
A new theoretical method to study electron transfer reactions in condensed phases is proposed by introducing the mean-field approximation into the constrained density functional theory/molecular mechanical method with a polarizable force field (CDFT/MMpol). The method enables us to efficiently calculate the statistically converged equilibrium and nonequilibrium free energies for diabatic states in an electron transfer reaction by virtue of the mean field approximation that drastically reduces the number of CDFT calculations...
April 21, 2017: Journal of Chemical Physics
Joanna Nizioł, Justyna Sekuła, Tomasz Ruman
Laser desorption/ionization mass spectrometry imaging (LDI-MSI) with gold nanoparticle-enhanced target (AuNPET) was used for visualization of small molecules in the rhubarb stalk (Rheum rhabarbarum L.). Analysis was focused on spatial distribution of biologically active compounds which are found in rhubarb species. Detected compounds belong to a very wide range of chemical compound classes such as anthraquinone derivatives and their glucosides, stilbenes, anthocyanins, flavonoids, polyphenols, organic acids, chromenes, chromanones, chromone glycosides and vitamins...
April 17, 2017: Phytochemistry
Hui Zhu, Xiao Liu, Ting Ting Zhu, Xiao Li Wang, Kun Ming Qin, Ke Pei, Bao Chang Cai
Prepared rhubarb, as one of the main processed products of rhubarb, has a good effect on promoting blood circulation. This paper described a rapid, sensitive and selective ultra-fast liquid chromatography with tandem mass spectrometry method for simultaneous quantification of five anthraquinones (rhein, aloe-emodin, chrysophanol, emodin and physcion) and gallic acid in plasma. Chromatographic separation was performed on an Extend C18 column at the temperature of 30°C using the mobile phase consisted of 0.1% aqueous formic acid and acetonitrile...
April 20, 2017: Journal of Separation Science
Chigozie Eunice Oramadike, Samuel Temitope Ogunbanwo
This study examined the antibacterial activity of Thymus vulgaris on multiple antibiotic resistant (MAR) Vibrio parahaemolyticus and Vibrio fluvialis isolated from shrimps. The ethanol extract of T. vulgaris antibacterial properties was assessed using the agar diffusion method. Survival of test organisms in shrimp meat using different concentrations of T. vulgaris was done using standard method. The quantitative and qualitative phytochemical tests of T. vulgaris extract were determined. The ethanol extract had antimicrobial activities on the test organisms showing 20...
April 2017: Journal of Food Science and Technology
Verónica I Dumit, Ralf M Zerbes, Stephanie Kaeser-Pebernard, Michal Rackiewicz, Mona T Wall, Christine Gretzmeier, Victoria Küttner, Martin van der Laan, Ralf J Braun, Jörn Dengjel
The anthraquinone emodin has been shown to have antineoplastic properties and a wealth of unconnected effects have been linked to its use, most of which are likely secondary outcomes of the drug treatment. The primary activity of emodin on cells has remained unknown. In the present study we demonstrate dramatic and extensive effects of emodin on the redox state of cells and on mitochondrial homeostasis, irrespectively of the cell type and organism, ranging from the yeast Saccharomyces cerevisiae to human cell lines and primary cells...
March 21, 2017: Oncotarget
Katarína Bruňáková, Eva Čellárová
Beside the high post-cryogenic recovery rate, a reinstated scale of secondary metabolites in recovered plant tissues represents another inevitable aspect of an effective cryopreservation protocol for medicinal plants. The current study was aimed at evaluation of the elicitation potential of cryogenic treatment on secondary metabolism of some Hypericum species. In agreement with our assumption, the cold stimuli applied during the pre-cryogenic phase increased the tolerance to low temperatures (-196°C) in H...
April 13, 2017: Journal of Biotechnology
Si-Si Zhou, Jian-Guo Jiang
Fatigue, a phenomenon which is believed to be caused by body exercise, can lead to the failure of predetermined exercise intensity maintenance and sport ability declination. The usage of traditional Chinese medicine (TCM) in the treatment of fatigue has long been practiced in clinical and showed significant effects. This article covers related literatures in recent years and sorts the effective ingredients from TCM for treating fatigue into a few categories including alkaloids, saponins, polysaccharides, polyphenols, polypeptide, terpene, proteins and other active ingredients...
April 14, 2017: Current Medicinal Chemistry
Lianshun Ma, Yaping Yang, Zizhang Yin, Mei Liu, Liwei Wang, Lixin Chen, Linyan Zhu, Haifeng Yang
Emodin is a natural anthraquinone derivative isolated from the Rheum palmatum. Recent studies demonstrated that emodin has anti-cancer activity in different kinds of human cancer cell lines. However, the underlying mechanism has not been very well studied. Our previous studies showed chloride channels is an important target of anti-cancer drugs. Therefore, the purpose of this research was aimed to explore the role of chloride channels involving in the anti-cancer activity of emodin. The proliferation, cell cycle arrest and apoptosis of poorly differentiated human nasopharyngeal carcinoma cells (CNE-2Z) and normal nasopharyngeal epithelial cells (NP69-SV40T) were detected by 3-(4,5-dimethylthiazol-2-yl) -2,5-diphenyltetrazolium bromide(MTT)and flow cytometry...
April 12, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Atila Basoglu, Simone Dirkmann, Nader Zahedi Golpayegani, Silke Vortherms, Jan Tentrop, Dominica Nowottnik, Helge Prinz, Roland Fröhlich, Klaus Müller
Novel analogues of oxadiazole-substituted naphtho[2,3-b]thiophene-4,9-diones were synthesized in which the tricyclic quinone skeleton was systematically replaced with simpler moieties, such as structures with fewer rings and open-chain forms, while the oxadiazole ring was maintained. In addition, variants of the original 1,2,4-oxadiazole ring were explored. Overall, the complete three-ring quinone was essential for potent suppression of human keratinocyte hyperproliferation, whereas analogous anthraquinones were inactive...
April 3, 2017: European Journal of Medicinal Chemistry
Nikolay V Lukashev, Gennadii A Grabovyi, Dmitry A Erzunov, Alexey V Kazantsev, Gennadij V Latyshev, Alexei D Averin, Irina P Beletskaya
Cu- and Pd-catalyzed arylation of aminocholanes has been described for the first time. While this Cu-catalyzed protocol provides high yields in reactions of aminocholanes with iodoarenes, Pd catalysis was found to be preferable for the reactions of aminocholanes with dichloroanthraquinones. UV-vis titration of bis(cholanylamino)anthraquinones with a series of cations demonstrated their high binding affinity to Cu(2+), Al(3+), and Cr(3+).
2017: Beilstein Journal of Organic Chemistry
P Madhusudhana Reddy, Shih-Rong Hsieh, Chi-Jung Chang, Jing-Yuan Kang
Cyanide (CN̄) is one of the most toxic material to the human and environment. It is very important to develop the diagnostic tools for the detection of CN̄ ions. Moreover, detection of the ions in an aqueous medium is a challenging task as water molecules interfere with the sensing mechanism. In this context, we prepared chemical sensor, S1, having anthraquinone as a signaling unit and thiourea as a binding site. This sensor exhibited distinct visual color and spectral changes in response to CN̄ ion over other testing anions in 50% aq...
April 3, 2017: Journal of Hazardous Materials
Rahman Gul, Syed Umer Jan, Syed Faridullah, Samiullah Sherani, Nusrat Jahan
The aim of this study was to evaluate the antioxidant activity, screening the phytogenic chemical compounds, and to assess the alkaloids present in the E. intermedia to prove its uses in Pakistani folk medicines for the treatment of asthma and bronchitis. Antioxidant activity was analyzed by using 2,2-diphenyl-1-picryl-hydrazyl-hydrate assay. Standard methods were used for the identification of cardiac glycosides, phenolic compounds, flavonoids, anthraquinones, and alkaloids. High performance liquid chromatography (HPLC) was used for quantitative purpose of ephedrine alkaloids in E...
2017: TheScientificWorldJournal
Sumbul Afreen, Tooba Naz Shamsi, Mohd Affan Baig, Nadeem Ahmad, Sadaf Fatima, M Irfan Qureshi, Md Imtaiyaz Hassan, Tasneem Fatma
A novel extracellular laccase enzyme produced from Spirulina platensis CFTRI was purified by ultrafiltration, cold acetone precipitation, anion exchange and size exclusion chromatography with 51.5% recovery and 5.8 purification fold. The purified laccase was a monomeric protein with molecular mass of ~66 kDa that was confirmed by zymogram analysis and peptide mass fingerprinting. The optimum pH and temperature of the enzyme activity was found at 3.0 and 30°C using ABTS as substrate but the enzyme was quite stable at high temperature and alkaline pH...
2017: PloS One
Myungsam Jen, Sebok Lee, Kooknam Jeon, Shafqat Hussain, Yoonsoo Pang
We report time-resolved stimulated Raman spectra of alizarin in DMSO solution with 403 nm excitation. Upon photoexcitation, the intramolecular proton transfer reaction of alizarin occurs in 70-80 fs, which is confirmed both by the population growth and the frequency and bandwidth changes of skeletal vibrational modes of alizarin. Interestingly, the vibrational frequencies of ν(C=C) and ν(C=O) show opposite shifts during the reaction, which may implicate changes in the resonance structure of anthraquinone and the attached carbonyl group...
April 4, 2017: Journal of Physical Chemistry. B
Qing Zhao, Zhiqiang Zhu, Jun Chen
Organic carbonyl electrode materials that have the advantages of high capacity, low cost and being environmentally friendly, are regarded as powerful candidates for next-generation stationary and redox flow rechargeable batteries (RFBs). However, low carbonyl utilization, poor electronic conductivity and undesired dissolution in electrolyte are urgent issues to be solved. Here, we summarize a molecular engineering approach for tuning the capacity, working potential, concentration of active species, kinetics, and stability of stationary and redox flow batteries, which well resolves the problems of organic carbonyl electrode materials...
April 3, 2017: Advanced Materials
Bin Yao, Yue Zhou, Xichong Ye, Rong Wang, Jie Zhang, Xinhua Wan
An electron-deficient star-shaped molecule based on anthraquinone imide was synthesized and characterized. It showed high electron accommodating capacity and strong electron-withdrawing ability with a low-lying lowest unoccupied molecular orbital (LUMO) of -4.10 eV. In addition, it exhibited panchromatic electrochromism attributed to the simultaneous presence of π*-π* transitions and intervalence charge transfer (IV-CT) upon one-electron reduction, and revealed long-term stability in electron gain and loss due to the proper LUMO energy level and ordered intermolecular assembly...
April 3, 2017: Organic Letters
Martin Kuss-Petermann, Margherita Orazietti, Markus Neuburger, Peter Hamm, Oliver S Wenger
The photochemistry of a molecular pentad composed of a central anthraquinone (AQ) acceptor flanked by two Ru(bpy)3(2+) photosensitizers and two peripheral triarylamine (TAA) donors was investigated by transient IR and UV-vis spectroscopies in the presence of 0.2 M p-toluenesulfonic acid (TsOH) in deaerated acetonitrile. In ∼15% of all excited pentad molecules, AQ is converted to its hydroquinone form (AQH2) via reversible intramolecular electron transfer from the two TAA units (τ = 65 ps), followed by intermolecular proton transfer from TsOH (τ ≈ 3 ns for the first step)...
March 31, 2017: Journal of the American Chemical Society
Guangfei Liu, Shuang Qiu, Baiqing Liu, Yiying Pu, Zhanming Gao, Jing Wang, Ruofei Jin, Jiti Zhou
Both Fe(III)-bearing clay minerals and humic acids (HAs) are abundant in the soils and sediments. Previous studies have shown that bioreduction of structural Fe(III) in clay minerals could be accelerated by adding anthraquinone compound as a redox-active surrogate of HAs. However, a quinoid analogue could not reflect the adsorption and complexation properties of HA, and little is known about the effects of real HAs at environmental concentration on bioreduction of clay minerals. Here, it was shown that 10-200 mg l(-1) of natural or artificially synthesized HAs could effectively stimulate the bioreduction rate and extent of Fe(III) in both iron-rich nontronite NAu-2 and iron-deficient montmorillonite SWy-2...
March 30, 2017: Scientific Reports
Ying Luo, Hai-Yan Shen, Qing-Xiang Shen, Chao-Hui Cao, Min Zhang, Shi-Yin Long, Zong-Bao Wang, Jian-Wen Tan
A phytochemical study on the whole plant of Spermacoce latifolia led to the isolation of a new anthraquinone, 1,2,6-trihydroxy-5-methoxy-9,10-anthraquinone (1), and a new naphthoquinone, (2R)-6-hydroxy-7-methoxy-dehydroiso-α-lapachone (2), together with three known anthraquinones (3-5). Their structures were established on the basis of detailed spectroscopic analysis, including one- and two-dimensional NMR, ESI-MS, and HR-ESI-MS techniques. All the compounds were isolated from S. latifolia for the first time...
March 30, 2017: Journal of Asian Natural Products Research
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