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Lauren B Cooper, Xiaojuan Mi, Robert J Mentz, Jennifer B Green, Kevin J Anstrom, Adrian F Hernandez, Lesley H Curtis
BACKGROUND: Several diabetes mellitus (DM) therapies are associated with worse heart failure (HF) outcomes, yet limited data exist characterizing routine DM management based on HF status. HYPOTHESIS: DM medications prescribed for patients with HF will differ in meaningful ways from patients without HF, and co-morbidities will impact the choice of medications prescribed. METHODS: Using Medicare fee-for-service claims data, we identified patients with newly treated DM between 2008 and 2011 and used multivariable logistic regression to assess associations between baseline HF status and DM medication use...
October 26, 2016: Clinical Cardiology
Jorge Barros, Susana Morales, Orietta Echávarri, Arnol García, Jaime Ortega, Takeshi Asahi, Claudia Moya, Ronit Fischman, María P Maino, Catalina Núñez
Objective: To analyze suicidal behavior and build a predictive model for suicide risk using data mining (DM) analysis. Methods: A study of 707 Chilean mental health patients (with and without suicide risk) was carried out across three healthcare centers in the Metropolitan Region of Santiago, Chile. Three hundred forty-three variables were studied using five questionnaires. DM and machine-learning tools were used via the support vector machine technique. Results: The model selected 22 variables that, depending on the circumstances in which they all occur, define whether a person belongs in a suicide risk zone (accuracy = 0...
October 20, 2016: Revista Brasileira de Psiquiatria
M Ganesh Kamath, C Ganesh Pai, Asha Kamath
BACKGROUND: Little data exist on the progression of recurrent acute (RAP) and chronic pancreatitis (CP) from regions from where the entity of tropical chronic pancreatitis was originally described. The study aimed to follow up patients with RAP and CP seen at a southern Indian centre for progression of disease over time. METHODS: Prospectively enrolled patients with RAP and CP were followed up, and the alcoholic and idiopathic subgroups were assessed for progression of structural and functional changes in the organ...
October 26, 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
Patrycja Boguta, Piotr M Pieczywek, Zofia Sokołowska
The main aim of this study was the application of excitation-emission fluorescence matrices (EEMs) combined with two decomposition methods: parallel factor analysis (PARAFAC) and nonnegative matrix factorization (NMF) to study the interaction mechanisms between humic acids (HAs) and Zn(II) over a wide concentration range (0-50 mg·dm(-3)). The influence of HA properties on Zn(II) complexation was also investigated. Stability constants, quenching degree and complexation capacity were estimated for binding sites found in raw EEM, EEM-PARAFAC and EEM-NMF data using mathematical models...
October 22, 2016: Sensors
Ying Du, Juan Chen, Man-Hua Chen, Sheng-Hua Yang, Sha Li, Yuan-Lin Guo, Cheng-Gang Zhu, Rui-Xia Xu, Qian Dong, Jian-Jun Li
BACKGROUND: Diabetes mellitus (DM) is associated with coronary artery disease (CAD) progression. Although previous studies have demonstrated the association of lipid and lipoprotein ratios with CAD, no data are currently available concerning the relationship between lipid and lipoprotein ratios and the severity of new on-set CAD in diabetics. Therefore, the aim of the present study was to investigate the usefulness of lipid and lipoprotein ratios in predicting the severity of CAD in patients with type 2 DM (T2DM)...
August 2016: Journal of Geriatric Cardiology: JGC
Rea Valaperta, Maddalena Gaeta, Rosanna Cardani, Fortunata Lombardi, Benedetta Rampoldi, Claudia De Siena, Francesca Mori, Barbara Fossati, Paola Gaia, Ottavia Eleonora Ferraro, Simona Villani, Sara Iachettini, Marco Piccoli, Federica Cirillo, Enrico Pusineri, Giovanni Meola, Elena Costa
BACKGROUND: Myotonic dystrophy (DM) is a genetic disorder caused by nucleotide repeats expansion. Sudden death represents the main cause of mortality in DM patients. Here, we investigatedthe relationship between serum cardiac biomarkers with clinical parameters in DM patients. METHODS: Case-control study included 59 DM patients and 22 healthy controls. An additional group of 62 controls with similar cardiac defects to DM were enrolled. RESULTS: NT-proBNP, hs-cTnT and CK levels were significantly increased in DM patients compared to healthy subjects (p=0...
October 22, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
Nayara Ragi Baldoni, Jéssica Azevedo Aquino, Cristina Sanches-Giraud, Cláudia Di Lorenzo Oliveira, Roberta Carvalho de Figueiredo, Clareci Silva Cardoso, Thiago Reis Santos, Geisa Cristina Silva Alves, Amaury Lelis Dal Fabbro, André Oliveira Baldoni
AIMS: To perform a systematic review and meta-analysis to identify and analyze collective empowerment strategies for patients with Diabetes Mellitus (DM). METHODS: The systematic review was performed using PubMed/MEDLINE, Science Direct and BVS. The term "Diabetes Mellitus" was used with each of the following describers, along with the connector "AND": "self-care", "health education", "motivation" and "empowerment". Inclusion criteria were: intervention study with control group published between 2004 and 2014...
October 22, 2016: Primary Care Diabetes
Ching-Wen Pan, Meng-Hsien Chen, Lien-Siang Chou, Hsing-Juh Lin
Indo-Pacific humpback dolphins (Sousa chinensis) have attracted considerable attention due to their critically endangered status and related conservation issues, but their trophic relationships and ecological significance in coastal ecosystems are poorly understood. For instance, this species is noticeably more abundant in the Xin-Huwei River Estuary (Ex) of Western Taiwan than in the nearby Zhuoshui River Estuary (Ez), though it is unclear why the distribution shows such partitioning. To explore this topic, we conducted field surveys seasonally for two years from 2012 to 2013 and constructed Ecopath models of Ex, Ez, and an offshore site (Dm) to compare energy flow within the food webs...
2016: PloS One
Wencheng Zheng, Xiaoming Shang, Chunlai Zhang, Xiang Gao, Barry Robinson, Jing Liu
OBJECTIVES: Diabetic cardiomyopathy (DCM) is characterized by cardiac dysfunction, myocardial inflammation, interstitial fibrosis and cardiomyocytes apoptosis. The present study aimed to investigate the effects of carvedilol on cardiac function and the AKT/XIAP signaling pathway in DCM rats. METHODS: Male Wistar rats were randomly divided into 3 groups: the control group, diabetic mellitus (DM) group and DM with carvedilol treatment group. DM rats were induced by streptozotocin accompanied by high energy intake...
October 26, 2016: Cardiology
Yisong Hu, Xiaochang C Wang, Qiyuan Sun, Huu Hao Ngo, Zhenzhen Yu, Jialing Tang, Qionghua Zhang
Three PAC-DMBRs were developed for wastewater treatment under different PAC dosages with biomass concentrations averaged at 2.5, 3.5 and 5.0g/L. The DMBRs could be continuously operated at 40-100L/m(2)h, while higher fluxes were obtained within the PAC-DMBRs with hydraulic retention times varying in 4-10h. A dose of 1g/L PAC brought about obvious improvement in the sludge particle size distribution, settling, flocculating and dewatering properties due to the formation of biological PAC, and the sludge properties were further improved at a higher PAC dose (3g/L)...
October 15, 2016: Bioresource Technology
Alejandro Garbino, Derek M Nusbaum, Daniel M Buckland, Anil S Menon, Jonathan B Clark, Erik L Antonsen
The Stratex Project is a high altitude balloon flight that culminated in a freefall from 41,422 m (135,890 ft), breaking the record for the highest freefall to date. Crew recovery operations required an innovative approach due to the unique nature of the event as well as the equipment involved. The parachutist donned a custom space suit similar to a NASA Extravehicular Mobility Unit (EMU), with life support system mounted to the front and a parachute on the back. This space suit had a metal structure around the torso, which, in conjunction with the parachute and life support assembly, created a significant barrier to extraction from the suit in the event of a medical emergency...
2016: Aerospace Medicine and Human Performance
Michelle R Hoffmann, Peter A Senior, Stephanie T Jackson, Guylaine Ferland, Nancy Presse, Kailash Jindal, Ping Li, Abeer S Alzaben, Diana R Mager
PURPOSE: Patients with diabetes (DM) and chronic kidney disease (CKD) are at increased risk for suboptimal bone health. The study objective was to investigate the relationships between vitamin D (vitD), vitamin K1 (vitK1), and calcium intake with bone mineral density (BMD) and vitamin D status in an ambulatory population with DM and CKD. METHODS: Adults (age 18-80 years; n = 62) with DM and CKD (stages 1-4) were recruited from the Northern Alberta Renal Program...
October 25, 2016: Canadian Journal of Dietetic Practice and Research
Abhinav Totapally, Michael Leoncio, Fernando Beltramo, Keith Meyer, Andre Raszynski, Balagangadhar R Totapally
BACKGROUND: The purpose of this study was to explore the epidemiology and outcomes of hospitalized children with a diagnosis of accidental hypothermia. METHODS: The 2012 Kids' Inpatient Database, detailing discharge diagnoses in children admitted to US hospitals, was analyzed using ICD-9-DM codes to filter out relevant patients. Children ages 1 month to 17 years were included in the analysis. Demographic and outcome variables in the hypothermia group were compared with the rest of the patients...
October 25, 2016: Journal of Trauma and Acute Care Surgery
K M Meiburger, S Y Nam, E Chung, L J Suggs, S Y Emelianov, F Molinari
Blood vessels are the only system to provide nutrients and oxygen to every part of the body. Many diseases can have significant effects on blood vessel formation, so that the vascular network can be a cue to assess malicious tumor and ischemic tissues. Various imaging techniques can visualize blood vessel structure, but their applications are often constrained by either expensive costs, contrast agents, ionizing radiations, or a combination of the above. Photoacoustic imaging combines the high-contrast and spectroscopic-based specificity of optical imaging with the high spatial resolution of ultrasound imaging, and image contrast depends on optical absorption...
November 21, 2016: Physics in Medicine and Biology
Xuwei Zheng, Hongyu Peng, Donghui Zhao, Qin Ma, Kun Fu, Guo Chen, Qian Fan, Jinghua Liu
Aim. Diabetes mellitus (DM) is a major risk factor for cardiovascular disease. The implications of a diagnosis of DM are as severe as the diagnosis of coronary artery disease. For many patients with complex coronary artery disease, optimal revascularization strategy selection and optimal medical therapy are equally important. In this study, we compared the hemodynamic results of different stenting techniques for Medina 0,1,0 left main bifurcation lesions. Methods. We use idealized left main bifurcation models and computational fluid dynamics analysis to evaluate hemodynamic parameters which are known to affect the risk of restenosis and thrombosis at stented bifurcation...
2016: Journal of Diabetes Research
Yu Liu, Jinsong Han, Tao Liu, Zhonglu Yang, Hui Jiang, Huishan Wang
Objective. To investigate the effects of diabetes mellitus (DM) in patients undergoing off-pump coronary artery bypass grafting (OPCAB). Method. A total of 728 patients with DM and 1380 patients without DM who underwent OPCAB treatment from March 2012 to April 2015 were reviewed. The effects of DM on intraoperative variables and postoperative complications were determined using propensity score analysis. Results. Two well-matched subgroups were selected using propensity score analysis (DM = 728, no-DM = 728) to compare the perioperative outcome...
2016: BioMed Research International
Chien Chuang, Wen-Chien Fan, Yi-Tsung Lin, Fu-Der Wang
BACKGROUND: Klebsiella pneumoniae is the most common pathogen of community-acquired pyogenic liver abscess in East Asia. Diabetes mellitus (DM) is a well-established risk factor for K. pneumoniae liver abscess (KPLA). However, reports regarding the emergence of KPLA in non-diabetic patients are limited. RESULTS: A total 230 patients with KPLA from a medical center in Taiwan were identified retrospectively. The rate of DM in patients with KPLA was 44.4 % in 2011, 57...
2016: Gut Pathogens
Wen-Xia Li, Ying Cao, Meng-Chen Zou, Ying Huang, Ping Hu, Xiang-Rong Luo, Ya Jiang, Yao-Ming Xue, Fang Gao
OBJECTIVE: To investigate foot biomechanics characteristic of patients with type 2 diabetes mellitus. METHODS: This study was conducted among 303 patients with type 2 diabetes. The whole foot was divided into 10 regions, namely the first toe (T1); the second to fifth toes (T2-5); the first, second, third, fourth, and fifth metatarsals (M1, M2, M3, M4, and M5, respectively); midfoot (MF), and the heel medial (HM). Foot arch index, foot angle and maximum peak pressure (MPP) of the 10 regions were measured using a Footscan gait system...
October 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
Zhao-Guang Tan, Wei-Hong Gao, Xiang-Sheng Cai, Fang Wang, Hong-Xiang Hui
OBJECTIVE: To investigate the effect of glucagon-like peptide 1 (GLP-1) on cognitive dysfunction in diabetic rats. METHODS: Male SD rats were randomly divided into normal control group, diabetes mellitus (DM) group, and GLP-1 treatment group. Rat models of type 2 diabetes were established by high-sugar and high-fat feeding and streptozotocin (STZ) injection, and 25 days after the onset of diabetes, GLP-1 was infused in GLP-1 treatment group at the rate of 30 pmol·kg(-1)·min(-1) via a subcutaneous osmotic pump for 7 days...
October 20, 2016: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
Hyo-Jin Kang, Jung Min Chang, Joongyub Lee, Sung Eun Song, Sung Ui Shin, Won Hwa Kim, Min Sun Bae, Woo Kyung Moon
OBJECTIVES: To evaluate the diagnostic performance and radiation dose of single view cranio-caudal (CC) digital mammography (DM) plus mediolateral oblique (MLO) digital breast tomosynthesis (DBT) combined with synthesized mammography (SM) in comparison with two-view DM with or without DBT. MATERIAL AND METHODS: This study was approved by our institutional review board, and informed consent was obtained from 130 women. Paired two-view DM and single MLO-DBT with SM images were acquired, and four independent retrospective reading sessions of different combinations of DM, SM and DBT were performed for the presence of malignant tumors using jackknife alternative free-response receiver operator curve (JAFROC) methods...
November 2016: European Journal of Radiology
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