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https://www.readbyqxmd.com/read/28231703/effects-of-water-addition-to-total-mixed-ration-on-water-intake-nutrient-digestibility-wool-cortisol-and-blood-indices-in-corriedale-ewes
#1
Jalil Ghassemi Nejad, Byong-Wan Kim, Bae-Hun Lee, Kyung Il Sung, Ji-Yung Kim
Objective: The objective of this study was to determine the effect of adding water to total mixed ration (TMR) on fresh water intake, nutrient digestibility, wool cortisol, and blood indices in Corriedale ewes under hot and humid conditions. Methods: Nine non-pregnant Corriedale ewes (ave. BW = 41 ± 3.5 kg) were individually fed diets based on maintenance requirements in metabolic crates. Ewes were assigned to three treatment groups according to a triplicate 3×3 Latin Square design for 3 periods of 21 days duration each (9 ewes per treatment, 27 replications)...
February 23, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28231701/the-potential-interaction-between-ewe-body-condition-score-and-nutrition-during-very-late-pregnancy-and-lactation-on-the-performance-of-twin-bearing-ewes-and-their-lambs
#2
Lydia Cranston, Paul Kenyon, Rene Corner-Thomas, Steve Morris
Objective: The present study aimed to determine the impact of ewe BCS (over a range of 2.0 to 3.0) and nutritional treatments (consisting of differing herbage masses) during very late pregnancy and lactation and their potential interaction on the performance of twin-bearing ewes and their lambs to weaning. Methods: On day [42 of pregnancy, twin-bearing ewes with a body condition score (BCS) of 2.0, 2.5 or 3.0 were allocated to a "Moderate' or 'Unrestricted' nutritional treatment until day 95 of lactation (weaning)...
February 23, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28231700/effect-on-quanti-quality-milk-and-mozzarella-cheese-characteristics-with-further-increasing-the-level-of-dried-stoned-olive-pomace-in-diet-for-lactating-buffalo
#3
Agnese Taticchi, Settimio Bartocci, Maurizio Servili, Sabrina Di Giovanni, Mariano Pauselli, Evangelia Mourvaki, David Meo Zilio, Stefano Terramoccia
Objective: Following a previous report, an experiment was conducted to determine the effect of increasing level of DSOP (dried stoned olives pomaces) in the diet of lactating buffaloes on milk and mozzarella cheese yield and characteristics. Methods: Sixteen pluriparous buffaloes distributed into two groups were fed an isoenergetic (0.9 Milk FU/kg) and isoprotein (149 g/kg DM of crude protein) diet, with or without DSOP. Each animal received 17 kg DM/d. Samples of forages and concentrates were weekly collected and used for duplicate chemical analyses...
February 23, 2017: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/28230312/five-year-cost-effectiveness-of-patient-empowerment-programme-pep-for-type-2-diabetes-mellitus-in-primary-care
#4
J X Lian, Sarah M McGhee, C So, J Chau, Carlos Kh Wong, William Cw Wong, Cindy Lk Lam
This study evaluated the short-term cost-effectiveness of the Patient Empowerment Programme (PEP) for diabetes mellitus in Hong Kong. Propensity score matching was used to select a matched group of PEP and non-PEP subjects. A societal perspective was adopted to estimate the cost of PEP. The outcome measures were the cumulative incidence of all-cause mortality and diabetic complication over a five-year follow-up and the number needed to treat (NNT) to avoid one event. The incremental cost-effectiveness ratio (ICER) of cost per event avoided was calculated using the PEP cost per subject multiplied by the NNT...
February 23, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28230255/changes-in-pectin-characteristics-during-the-ripening-of-jujube-fruit
#5
Shenghua Ding, Rongrong Wang, Yang Dan, Gaoyang Li, Shiyi Ou
BACKGROUND: Pectin is relative to fruit maturation and loss of flesh firmness. In this research, changes in pectin characteristics, including pectin content, neutral sugar compositions, molecular weight (Mw ) distribution, and degree of methyl esterification (DM), in six different growth stages (S1-S6) of jujube fruit were assessed. RESULTS: The growth of jujube fruit corresponded to an increase in water-soluble pectin (WSP), and a decrease in Na2 CO3 -soluble pectin (SSP)...
February 23, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/28229380/cognitive-impairment-is-correlated-with-insulin-resistance-degree-the-pa-nico-study
#6
Antonietta Fava, Carmen Colica, Massimiliano Plastino, Demetrio Messina, Dario Cristiano, Carlo Opipari, Antonio Vaccaro, Gaetano Gorgone, Francesca Bosco, Alessandra Fratto, Matteo De Bartolo, Domenico Bosco
Several epidemiological studies have shown that Diabetes Mellitus (DM) or Insulin Resistance (IR) increases the risk of dementia. Besides, some authors suggested that poor glucose control to be associated with worse cognitive function. We aimed to assess cognitive functions and IR-degree over time in diabetic. We also evaluated whether a greater magnitude of cognitive decline could be related with their IR degree. We enrolled 335 diabetic patients and 142 non-diabetic subjects; participants were subdivided into three groups in accordance with their IRdegree assessed by Homa-Index (HI): Normal-HI (non-diabetic NHI < 2,6), Moderate-HI (MHI > 2,6 < 10) and High-HI (HHI > 10)...
February 23, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28229257/potential-ecological-risk-assessment-and-predicting-zinc-accumulation-in-soils
#7
Agnieszka Baran, Jerzy Wieczorek, Ryszard Mazurek, Krzysztof Urbański, Agnieszka Klimkowicz-Pawlas
The aims of this study were to investigate zinc content in the studied soils; evaluate the efficiency of geostatistics in presenting spatial variability of zinc in the soils; assess bioavailable forms of zinc in the soils and to assess soil-zinc binding ability; and to estimate the potential ecological risk of zinc in soils. The study was conducted in southern Poland, in the Malopolska Province. This area is characterized by a great diversity of geological structures and types of land use and intensity of industrial development...
February 22, 2017: Environmental Geochemistry and Health
https://www.readbyqxmd.com/read/28228754/proofreading-of-peptide-mhc-complexes-through-dynamic-multivalent-interactions
#8
REVIEW
Christoph Thomas, Robert Tampé
The adaptive immune system is able to detect and destroy cells that are malignantly transformed or infected by intracellular pathogens. Specific immune responses against these cells are elicited by antigenic peptides that are presented on major histocompatibility complex class I (MHC I) molecules and recognized by cytotoxic T lymphocytes at the cell surface. Since these MHC I-presented peptides are generated in the cytosol by proteasomal protein degradation, they can be metaphorically described as a window providing immune cells with insights into the state of the cellular proteome...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28227168/a-novel-method-for-splice-sites-prediction-using-sequence-component-and-hidden-markov-model
#9
Elham Pashaei, Alper Yilmaz, Mustafa Ozen, Nizamettin Aydin, Elham Pashaei, Alper Yilmaz, Mustafa Ozen, Nizamettin Aydin, Nizamettin Aydin, Alper Yilmaz, Elham Pashaei, Mustafa Ozen
With increasing growth of DNA sequence data, it has become an urgent demand to develop new methods to accurately predict the genes. The performance of gene detection methods mainly depend on the efficiency of splice site prediction methods. In this paper, a novel method for detecting splice sites is proposed by using a new effective DNA encoding method and AdaBoost.M1 classifier. Our proposed DNA encoding method is based on multi-scale component (MSC) and first order Markov model (MM1). It has been applied to the HS3D dataset with repeated 10 fold cross validation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28225992/serum-fluorescent-advanced-glycation-end-f-age-products-in-gestational-diabetes-patients
#10
João Paulo Lobo, Catiane Pompilio Brescansin, Izabella C R Santos-Weiss, Marciane Welter, Emanuel Maltempi de Souza, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Dayane Alberton
Objectives: Advanced glycation end products (AGEs) are involved in the pathogenesis and complications of diabetes mellitus (DM). Gestational DM (GDM) is characterized by increased glycemia and oxidative stress, which are factors associated with high serum AGE concentrations. The aim of this study was to evaluate the utility of a serum fluorescence AGE (F-AGE) method as a screening tool for gestational diabetes. Subjects and methods: Serum samples from 225 GDM patients and 217 healthy pregnant women (healthy controls) were diluted 50-fold in phosphate-buffered saline, and the AGEs were estimated by fluorometric analysis (λEx 350 nm/ λEm 440 nm)...
February 13, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28225861/predictors-of-subclinical-atherosclerosis-evaluated-by-carotid-intima-media-thickness-in-asymptomatic-young-women-with-type-1-diabetes-mellitus
#11
Rosane Kupfer, Manuella Rangel Larrúbia, Isabela Bussade, Joana Rodrigues Dantas Pereira, Giovanna A Balarini Lima, Marcio Antonio Epifanio, Claudio Domenico Sahione Schettino, Denise Prado Momesso
Objective: This study aimed to evaluate the occurrence and clinical predictors of subclinical atherosclerosis in asymptomatic, young adult women with type 1 DM. Subjects and methods: The study included 45 women with type 1 diabetes mellitus (DM) (aged 36 ± 9 years) who underwent carotid Doppler ultrasound evaluation to determine the carotid artery intima-media thickness (CIMT) and to assess the occurrence of carotid artery plaques. Insulin sensitivity was assessed by estimated glucose disposal rate (eGDR), and metabolic syndrome (MS) was defined by the World Health Organization criteria...
February 16, 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28225510/effective-use-of-calcineurin-inhibitor-in-combination-therapy-for-interstitial-lung-disease-in-patients-with-dermatomyositis-and-polymyositis
#12
Yasuhiro Shimojima, Wataru Ishii, Masayuki Matsuda, Dai Kishida, Shu-Ichi Ikeda
OBJECTIVE: The current study demonstrated the potential use of calcineurin inhibitor (CNI) in combination therapy for interstitial lung disease (ILD) complicated with dermatomyositis (DM) and polymyositis (PM). METHODS: Thirty DM/PM patients with ILD were enrolled in this study. Continuous intravenous administration of cyclosporine A (IV-CsA) was simultaneously started with corticosteroid in patients presenting more than two respiratory distress factors as follows: <70 mmHg of PaO2, percentage of vital capacity <70%, and/or exertional dyspnea...
March 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28224697/antioxidant-treatment-ameliorates-diabetes-induced-dysfunction-of-the-vas-deferens-in-a-rat-model
#13
P Tsounapi, M Honda, F Dimitriadis, S Shimizu, T Shiomi, K Hikita, M Saito, S Tomita, N Sofikitis, A Takenaka
Diabetes mellitus (DM) affects the male ejaculatory function. This study was designed to evaluate the role of oxidative stress in the development of diabetes-induced dysfunction of vas deferens (VD) in the rat. DM was induced by streptozotocin in 40 male Wistar rats. Subsequently, the diabetic animals were divided into three groups: DM group, DM + Eda group and DM + Tau group. These groups were administered saline, edaravone and taurine, respectively, daily for 4 weeks. Another group of ten rats served as a control group...
February 22, 2017: Andrologia
https://www.readbyqxmd.com/read/28224635/infections-and-vaccinations-as-possible-triggers-of-inflammatory-myopathies
#14
Vidya Limaye, Caroline Smith, Barbara Koszyca, Peter Blumbergs, Sophia Otto
INTRODUCTION: The role of vaccinations and infections in triggering idiopathic inflammatory myopathies (IIM) has not been confirmed. METHODS: Among patients with histologically-confirmed myositis, infections or vaccinations administered prior to myositis onset were determined. The characteristics of this group were compared with controls (myositis patients without prior infection or vaccination). RESULTS: The frequency of IIM with a prior vaccination was 20 of 206, (9...
February 22, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28224486/human-herpes-virus-6-encephalitis-causing-severe-anterograde-amnesia-associated-with-rituximab-azathioprine-and-prednisolone-combination-therapy-for-dermatomyositis
#15
Thomas Baumer, Charlie Fry, Sebastian Luppe, Harsha Gunawardena, Kasia Sieradzan
Human herpes virus-6 (HHV-6) reactivation is a well-recognised complication following haematological stem cell transplantation, but it is novel in the context of combination immunomodulatory therapy for autoimmune disease. We report a case of severe anterograde amnesia caused by HHV-6 encephalitis in a young female patient on rituximab, azathioprine and prednisolone for dermatomyositis (DM). The use of targeted biologic treatments for systemic autoimmune connective tissue diseases (CTDs) is increasing, particularly when refractory to conventional management...
February 21, 2017: Journal of Neurovirology
https://www.readbyqxmd.com/read/28224415/effectiveness-of-workplace-interventions-in-return-to-work-for-musculoskeletal-pain-related-and-mental-health-conditions-an-update-of-the-evidence-and-messages-for-practitioners
#16
REVIEW
K L Cullen, E Irvin, A Collie, F Clay, U Gensby, P A Jennings, S Hogg-Johnson, V Kristman, M Laberge, D McKenzie, S Newnam, A Palagyi, R Ruseckaite, D M Sheppard, S Shourie, I Steenstra, D Van Eerd, B C Amick
Purpose The objective of this systematic review was to synthesize evidence on the effectiveness of workplace-based return-to-work (RTW) interventions and work disability management (DM) interventions that assist workers with musculoskeletal (MSK) and pain-related conditions and mental health (MH) conditions with RTW. Methods We followed a systematic review process developed by the Institute for Work & Health and an adapted best evidence synthesis that ranked evidence as strong, moderate, limited, or insufficient...
February 21, 2017: Journal of Occupational Rehabilitation
https://www.readbyqxmd.com/read/28224059/identification-of-downy-mildew-resistance-gene-candidates-by-positional-cloning-in-maize-zea-mays-subsp-mays-poaceae
#17
Jae Yoon Kim, Jun-Cheol Moon, Hyo Chul Kim, Seungho Shin, Kitae Song, Kyung-Hee Kim, Byung-Moo Lee
PREMISE OF THE STUDY: Positional cloning in combination with phenotyping is a general approach to identify disease-resistance gene candidates in plants; however, it requires several time-consuming steps including population or fine mapping. Therefore, in the present study, we suggest a new combined strategy to improve the identification of disease-resistance gene candidates. METHODS AND RESULTS: Downy mildew (DM)-resistant maize was selected from five cultivars using a spreader row technique...
February 2017: Applications in Plant Sciences
https://www.readbyqxmd.com/read/28223216/mir-181c-restrains-nitration-stress-of-endothelial-cells-in-diabetic-db-db-mice-through-inhibiting-the-expression-of-foxo1
#18
Guangwei Yang, Yuanbo Wu, Shandong Ye
Endothelial dysfunction played an important role in the progression of diabetes mellitus (DM). miR-181c has been implicated in many diseases, including DM. However, the molecular mechanisms of miR-181c regulate this process remained poorly understood. Healthy ICR mice were divided into control group (n = 10) and db/db DM group (n = 10). The expression of miR-181c and FoxO1 were both investigated in diabetic db/db mice or high glucose-induced endothelial cells (MAECs and END-D). Here we found that down-regulation of miR-181c and the activation of FoxO1/iNOS were observed in mice and endothelial cells...
February 18, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28222832/the-impact-of-divergent-breed-types-and-diets-on-methane-emissions-rumen-characteristics-and-performance-of-finishing-beef-cattle
#19
C-A Duthie, M Haskell, J J Hyslop, A Waterhouse, R J Wallace, R Roehe, J A Rooke
This study was undertaken to further develop our understanding of the links between breed, diet and the rumen microbial community and determine their effect on production characteristics and methane (CH4) emissions from beef cattle. The experiment was of a 2×2 factorial design, comprising two breeds (crossbred Charolais (CHX); purebred Luing (LU)) and two diets (concentrate-straw or silage-based). In total, 80 steers were used and balanced for sire within each breed, farm of origin and BW across diets. The diets (fed as total mixed rations) consisted of (g/kg dry matter (DM)) forage to concentrate ratios of either 500 : 500 (Mixed) or 79 : 921 (Concentrate)...
February 22, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28219956/mineral-status-in-canine-medial-coronoid-process-disease-a-cohort-study-using-analysis-of-hair-by-mass-spectrometry
#20
M Davies, J West, C Williams, D S Gardner
In several species, developmental skeletal diseases involving abnormal endochondral ossification have been associated with imbalanced mineral intake. Hair analysis reflects long-term mineral status. To determine the mineral content of hair from dogs with or without medial coronoid process disease (MCPD). Dogs with MCPD have a different profile of minerals known to influence metalloenzymes involved in endochondral ossification. After cleansing, chelation and acid digestion of hair samples (n=79 in total: control dogs, n=70 v MCPD, n=9), mineral profile (7 major and 25 trace elements) was determined by inductively coupled plasma-mass spectrometry...
February 20, 2017: Veterinary Record
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