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https://www.readbyqxmd.com/read/27911123/lichen-sclerosus-et-atrophicus-in-a-surgical-scar-treated-with-fractional-laser
#1
Marta Mendieta Eckert, Izaskun Ocerin Guerra, Nerea Landa Gundin
Lichen sclerosus et atrophicus (LSA) is a chronic inflammatory disease of unknown cause that typically affects the genital area(1). It has been reported in post-traumatic areas as a result of Koebner´s phenomenon. LSA responds poorly to treatment making it a therapeutic challenge(2). Laser therapy has been described for LSA with variable results(3,4).
December 2, 2016: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/27875011/characterization-of-tin-ethylene-glycol-solar-nanofluids-synthesized-by-laser
#2
Omar Torres-Mendieta, Rosa Mondragron, Verónica Puerto-Belda, Omel Mendoza-Yero, Jesús Lancis, J Enrique Bolivar, Gladys Mínguez-Vega
Solar energy is extended over wide geographical areas and is becoming an essential tool to keep the ever-increasing demand of energy with minimal environmental impact. A solar nanofluid is a novel solar receiver concept for efficient harvesting of solar radiation based on volumetric absorption of directly irradiated nanoparticles in a heat transfer fluid. Herein, the fabrication of a solar nanofluid by pulsed laser ablation in liquids was explored. This study was conducted with the ablation of bulk tin immersed in ethylene glycol with a femtosecond laser...
November 22, 2016: Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry
https://www.readbyqxmd.com/read/27784309/putrescine-treatment-reverses-%C3%AE-tocopherol-induced-desynchronization-of-polyamine-and-retinoid-metabolism-during-rat-liver-regeneration
#3
Lourdes Sánchez-Sevilla, Edgar Mendieta-Condado, Rolando Hernández-Muñoz
BACKGROUND: The pre-treatment with α-tocopherol inhibits progression of rat liver proliferation induced by partial hepatectomy (PH), by decreasing and/or desynchronizing cyclin D1 expression and activation into the nucleus, activation and nuclear translocation of STAT-1 and -3 proteins and altering retinoid metabolism. Interactions between retinoic acid and polyamines have been reported in the PH-induced rat liver regeneration. Therefore, we evaluated the effect of low dosage of α-tocopherol on PH-induced changes in polyamine metabolism...
October 26, 2016: Journal of Translational Medicine
https://www.readbyqxmd.com/read/27768300/quantum-mechanics-molecular-mechanics-free-energy-maps-and-nonadiabatic-simulations-for-a-photochemical-reaction-in-dna-cyclobutane-thymine-dimer
#4
Jesús Ignacio Mendieta-Moreno, Daniel G Trabada, Jesus Mendieta, James P Lewis, Paulino Gómez-Puertas, Jose Ortega
The absorption of ultraviolet radiation by DNA may result in harmful genetic lesions that affect DNA replication and transcription, ultimately causing mutations, cancer and/or cell death. We analyze the most abundant photochemical reaction in DNA, the cyclobutane thymine dimer, using hybrid quantum mechanics / molecular mechanics (QM/MM) techniques and QM/MM nonadiabatic molecular dynamics. We find that, due to its double helix structure, DNA presents a free energy barrier between non-reactive and reactive conformations leading to the photolesion...
October 21, 2016: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/27752186/approach-to-an-obstetric-prognosis-scale-the-modified-sofa-scale
#5
Lourdes A Blanco Esquivel, Jorge Macia Urbina, Hugo Mendieta Zerón
BACKGROUND: Severe obstetric morbidity constitutes a serious problem worldwide; however, an effective obstetrical prognosis scale is still missing. OBJECTIVE: To propose a modified Sequential Organ Failure Assessment Score (SOFA) score based on time before reaching specialized medical attention. METHOD: This was an ambispective, descriptive study, including all women treated at the Obstetrical Intensive Care Unit (OICU) of the "Mónica Pretelini Sáenz" Maternal-Perinatal Hospital (HMPMPS), Toluca, Mexico, from June 2009 to June 2013...
September 2016: Ghana Medical Journal
https://www.readbyqxmd.com/read/27751411/sclerotherapy-with-6-polidocanol-solution-in-patients-with-placenta-accreta
#6
Ricardo Mauricio Malagón Reyes, Rubén Castorena de Ávila, María de Jesús Ángeles Vázquez, César Augusto Núñez Monteagudo, Hugo Mendieta Zerón
OBJECTIVE: Placenta accreta is one of the main obstetrical complications worldwide. The aim of this study was to report the experience of managing placenta accreta with a 6% polidocanol solution sclerotherapy. MATERIALS AND METHODS: We selected patients between 37 weeks of gestation and 38 weeks of gestation, diagnosed with placenta accreta, treated at the Maternal Perinatal Hospital "Monica Pretelini Sáenz", Toluca, Mexico, during the period from November 2013 to August 2014...
October 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27682141/kap-surveys-and-dengue-control-in-colombia-disentangling-the-effect-of-sociodemographic-factors-using-multiple-correspondence-analysis
#7
Diana Rocío Higuera-Mendieta, Sebastián Cortés-Corrales, Juliana Quintero, Catalina González-Uribe
During the last few decades, several studies have analyzed and described knowledge, attitudes, and practices (KAP) of populations regarding dengue. However, few studies have applied geometric data analytic techniques to generate indices from KAP domains. Results of such analyses have not been used to determine the potential effects of sociodemographic variables on the levels of KAP. The objective was to determine the sociodemographic factors related to different levels of KAP regarding dengue in two hyper-endemic cities of Colombia, using a multiple correspondence analysis (MCA) technique...
September 2016: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/27617938/treatment-of-rosacea-with-topical-ivermectin-cream-a-series-of-34-cases
#8
Marta Mendieta Eckert, Nerea Landa Gundin
Rosacea is a highly prevalent, chronic inflammatory disease. The use of topical ivermectin cream has recently been described in the treatment of rosacea in three clinical trials. We report our experience in a series of 34 patients treated with topical ivermectin cream. The results are a reflection of the reality of clinical practice and the perception of patients of the treatment. We also evaluate the efficacy in cases of mild rosacea and erythematotelangiectatic rosacea which have not been studied in trials...
2016: Dermatology Online Journal
https://www.readbyqxmd.com/read/27612732/synthesis-of-silver-nanoparticles-using-aqueous-extracts-of-heterotheca-inuloides-as-reducing-agent-and-natural-fibers-as-templates-agave-lechuguilla-and-silk
#9
Raúl A Morales-Luckie, Aldo Adrián Lopezfuentes-Ruiz, Oscar F Olea-Mejía, Argueta-Figueroa Liliana, Víctor Sanchez-Mendieta, Witold Brostow, Juan P Hinestroza
Silver nanoparticles (Ag NPs) were synthesized using a one-pot green methodology with aqueous extract of Heterotheca inuloides as a reducing agent, and the support of natural fibers: Agave lechuguilla and silk. UV-Vis spectroscopy, X-Ray photoelectron spectroscopy XPS and transmission electron microscopy TEM were used to characterize the resulting bionanocomposite fibers. The average size of the Ag NPs was 16nm and they exhibited low polydispersity. XPS studies revealed the presence of only metallic Ag in the nanoparticles embedded in Agave...
December 1, 2016: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27513256/nf-%C3%AE%C2%BA%C3%AE-and-sod-expression-in-preeclamptic-placentas
#10
Abraham Silva Carmona, Hugo Mendieta Zerón
BACKGROUND/AIM: Preeclampsia is a leading cause of maternal death in the developing world. Our aim was to quantify and compare messenger (mRNA) expression of nuclear factor-kappa beta (NF-κΒ) and superoxide dismutase (SOD) in control patients with preeclampsia and without preeclampsia with or without familial hereditary background. MATERIALS AND METHODS: Four groups of patients were formed depending on the presence or absence of preeclampsia and presence or absence of familial history for preeclampsia...
2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27495897/disruption-of-motor-behavior-and-injury-to-the-cns-induced-by-3-thienylboronic-acid-in-mice
#11
E D Farfán-García, M Pérez-Rodríguez, C Espinosa-García, N T Castillo-Mendieta, M Maldonado-Castro, E Querejeta, J G Trujillo-Ferrara, M A Soriano-Ursúa
The scarcity of studies on boron containing compounds (BCC) in the medicinal field is gradually being remedied. Efforts have been made to explore the effects of BCCs due to the properties that boron confers to molecules. Research has shown that the safety of some BCCs is similar to that found for boron-free compounds (judging from the acute toxicological evaluation). However, it has been observed that the administration of 3-thienylboronic acid (3TB) induced motor disruption in CD1 mice. In the current contribution we studied in deeper form the disruption of motor performance produced by the intraperitoneal administration of 3TB in mice from two strains (CD1 and C57BL6)...
September 15, 2016: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/27491989/complete-genome-sequence-of-zika-virus-isolated-in-mexico-2016
#12
José Alberto Díaz-Quiñonez, Rocío Peña-Alonso, Edgar Mendieta-Condado, Fabiola Garcés-Ayala, Elizabeth González-Durán, Noé Escobar-Escamilla, Mauricio Vázquez-Pichardo, María de la Luz Torres-Rodríguez, Alma Núñez-León, Belem Torres-Longoria, Irma López-Martínez, Cuitláhuac Ruíz-Matus, Pablo Kuri-Morales, José Ernesto Ramírez-González
Zika virus belongs to the genus Flavivirus, and its spread remains an international public health emergency. In this report, we describe the obtainment and molecular characterization of a complete viral genome through the direct metagenomic analysis from saliva from an autochthonous transmission case in Mexico.
2016: Genome Announcements
https://www.readbyqxmd.com/read/27464997/in-situ-decoration-of-graphene-sheets-with-gold-nanoparticles-synthetized-by-pulsed-laser-ablation-in-liquids
#13
Rafael Torres-Mendieta, David Ventura-Espinosa, Sara Sabater, Jesus Lancis, Gladys Mínguez-Vega, Jose A Mata
The demand for nanocomposites of graphene and carbonaceous materials decorated with metallic nanoparticles is increasing on account of their applications in science and technology. Traditionally, the production of graphene-metal assemblies is achieved by the non-environmentally friendly reduction of metallic salts in carbonaceous suspensions. However, precursor residues during nanoparticle growth may reduce their surface activity and promote cross-chemical undesired effects. In this work we present a laser-based alternative to synthesize ligand-free gold nanoparticles that are anchored onto the graphene surface in a single reaction step...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27454774/pharmacokinetics-in-wistar-rats-of-5-4-carboxybutanoyl-amino-2-hydroxybenzoic-acid-a-novel-synthetic-derivative-of-5-aminosalicylic-acid-5-asa-with-possible-anti-inflammatory-activity
#14
Aurelio Romero-Castro, Mara Gutiérrez-Sánchez, José Correa-Basurto, Martha Cecilia Rosales Hernández, Itzia Irene Padilla Martínez, Jessica Elena Mendieta-Wejebe
5-[(4-carboxybutanoyl)amino]-2-hydroxybenzoic acid (C2) is a novel synthetic derivative of 5-aminosalicylic acid (5-ASA), which is currently being evaluated ex vivo as an anti-inflammatory agent and has shown satisfactory results. This study aimed to obtain the pharmacokinetic profiles, tissue distribution and plasma protein binding of C2 in Wistar Rats. Additionally, an HPLC method was developed and validated to quantify C2 in rat plasma. The pharmacokinetic profiles of intragastric, intravenous and intraperitoneal administration routes at singles doses of 100, 50, and 100 mg/kg, respectively, were studied in Wistar rats...
2016: PloS One
https://www.readbyqxmd.com/read/27387544/noninvasive-ventilation-for-severely-acidotic-patients-in-respiratory-intermediate-care-units-precision-medicine-in-intermediate-care-units
#15
Juan F Masa, Isabel Utrabo, Javier Gomez de Terreros, Myriam Aburto, Cristóbal Esteban, Enric Prats, Belén Núñez, Ángel Ortega-González, Luis Jara-Palomares, M Jesus Martin-Vicente, Eva Farrero, Alicia Binimelis, Ernest Sala, José C Serrano-Rebollo, Emilia Barrot, Raquel Sánchez-Oro-Gomez, Ramón Fernández-Álvarez, Francisco Rodríguez-Jerez, Javier Sayas, Pedro Benavides, Raquel Català, Francisco J Rivas, Carlos J Egea, Antonio Antón, Patricia Peñacoba, Ana Santiago-Recuerda, M A Gómez-Mendieta, Lidia Méndez, José J Cebrian, Juan A Piña, Enrique Zamora, Gonzalo Segrelles
BACKGROUND: Severe acidosis can cause noninvasive ventilation (NIV) failure in chronic obstructive pulmonary disease (COPD) patients with acute hypercapnic respiratory failure (AHRF). NIV is therefore contraindicated outside of intensive care units (ICUs) in these patients. Less is known about NIV failure in patients with acute cardiogenic pulmonary edema (ACPE) and obesity hypoventilation syndrome (OHS). Therefore, the objective of the present study was to compare NIV failure rates between patients with severe and non-severe acidosis admitted to a respiratory intermediate care unit (RICU) with AHRF resulting from ACPE, COPD or OHS...
2016: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/27352029/adsorption-orientations-and-immunological-recognition-of-antibodies-on-graphene
#16
J G Vilhena, A C Dumitru, Elena T Herruzo, Jesús I Mendieta-Moreno, Ricardo Garcia, P A Serena, Rubén Pérez
Large-scale molecular dynamics (MD) simulations and atomic force microscopy (AFM) in liquid are combined to characterize the adsorption of Immunoglobulin G (IgG) antibodies over a hydrophobic surface modeled with a three-layer graphene slab. We consider explicitly the water solvent, simulating systems with massive sizes (up to 770 000 atoms), for four different adsorption orientations. Protocols based on steered MD to speed up the protein diffusion stage and to enhance the dehydration process are combined with long simulation times (>150 ns) in order to make sure that the final adsorption states correspond to actual stable configurations...
July 7, 2016: Nanoscale
https://www.readbyqxmd.com/read/27329537/current-data-regarding-the-structure-toxicity-relationship-of-boron-containing-compounds
#17
E D Farfán-García, N T Castillo-Mendieta, F J Ciprés-Flores, I I Padilla-Martínez, J G Trujillo-Ferrara, M A Soriano-Ursúa
Boron is ubiquitous in nature, being an essential element of diverse cells. As a result, humans have had contact with boron containing compounds (BCCs) for a long time. During the 20th century, BCCs were developed as antiseptics, antibiotics, cosmetics and insecticides. Boric acid was freely used in the nosocomial environment as an antiseptic and sedative salt, leading to the death of patients and an important discovery about its critical toxicology for humans. Since then the many toxicological studies done in relation to BCCs have helped to establish the proper limits of their use...
September 6, 2016: Toxicology Letters
https://www.readbyqxmd.com/read/27313601/current-advances-in-the-biochemical-and-physiological-aspects-of-the-treatment-of-type-2-diabetes-mellitus-with-thiazolidinediones
#18
REVIEW
D Alemán-González-Duhart, F Tamay-Cach, S Álvarez-Almazán, J E Mendieta-Wejebe
The present review summarizes the current advances in the biochemical and physiological aspects in the treatment of type 2 diabetes mellitus (DM2) with thiazolidinediones (TZDs). DM2 is a metabolic disorder characterized by hyperglycemia, triggering the abnormal activation of physiological pathways such as glucose autooxidation, polyol's pathway, formation of advance glycation end (AGE) products, and glycolysis, leading to the overproduction of reactive oxygen species (ROS) and proinflammatory cytokines, which are responsible for the micro- and macrovascular complications of the disease...
2016: PPAR Research
https://www.readbyqxmd.com/read/27291831/factors-associated-with-psychological-distress-or-common-mental-disorders-in-migrant-populations-across-the-world
#19
Dolores Jurado, Renato D Alarcón, José M Martínez-Ortega, Yaiza Mendieta-Marichal, Luis Gutiérrez-Rojas, Manuel Gurpegui
We systematically review factors associated with the presence of psychological distress or common mental disorders in migrant populations. Articles published between January 2000 and December 2014 were reviewed and 85 applying multivariate statistical analysis were selected. Common mental disorders were significantly associated with socio-demographic and psychological characteristics, as observed in large epidemiological studies on general populations. The probability of common mental disorders occurrence differs significantly among migrant groups according to their region of origin...
June 9, 2016: Revista de Psiquiatrí́a y Salud Mental
https://www.readbyqxmd.com/read/27237821/current-tools-and-methods-in-molecular-dynamics-md-simulations-for-drug-design
#20
Maricarmen Hernández-Rodríguez, Martha C Rosales-Hernández, Jessica E Mendieta-Wejebe, Marlet Martínez-Archundia, José Correa Basurto
Molecular Dynamics (MD) simulations is a computational method that employs Newton's laws to evaluate the motions of water, ions, small molecules, and macromolecules or more complex systems, for example, whole viruses, to reproduce the behavior of the biological environment, including water molecules and lipid membranes. Specifically, structural motions, such as those that are dependent of the temperature and solute/solvent are very important to study the recognition pattern of ligand-protein or protein-protein complexes, in that sense, MD simulations are very useful because these motions can be modeled using this methodology...
May 30, 2016: Current Medicinal Chemistry
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