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Mickael Silva, Miguel P Machado, Diogo N Silva, Mirko Rossi, Jacob Moran-Gilad, Sergio Santos, Mario Ramirez, João André Carriço
Gene-by-gene approaches are becoming increasingly popular in bacterial genomic epidemiology and outbreak detection. However, there is a lack of open-source scalable software for schema definition and allele calling for these methodologies. The chewBBACA suite was designed to assist users in the creation and evaluation of novel whole-genome or core-genome gene-by-gene typing schemas and subsequent allele calling in bacterial strains of interest. chewBBACA performs the schema creation and allele calls on complete or draft genomes resulting from de novo assemblers...
March 15, 2018: Microbial Genomics
Kishore P Madhwani, P K Nag
Background: Use of laptops and hand-held devices increase the risk of musculoskeletal disorders (MSDs). More time spent on this activity adopting faulty postures, higher the risk of developing such injuries. This study addresses training on office ergonomics with emphasis on sustainable behavior change among employees to work in safe postures, as this is a top priority in the corporate environment, today. Aim: To explore training intervention methods that ensure wider coverage of awareness on office ergonomics, thereby promoting safer working and suggesting sustainable programs for behavior change and job enrichment...
May 2017: Indian Journal of Occupational and Environmental Medicine
Evgeny Krissinel, Ville Uski, Andrey Lebedev, Martyn Winn, Charles Ballard
Modern crystallographic computing is characterized by the growing role of automated structure-solution pipelines, which represent complex expert systems utilizing a number of program components, decision makers and databases. They also require considerable computational resources and regular database maintenance, which is increasingly more difficult to provide at the level of individual desktop-based CCP4 setups. On the other hand, there is a significant growth in data processed in the field, which brings up the issue of centralized facilities for keeping both the data collected and structure-solution projects...
February 1, 2018: Acta Crystallographica. Section D, Structural Biology
Anthony J Greenberg
Explosive growth in the amount of genomic data is matched by increasing power of consumer grade computers. Even applications that require powerful servers can be quickly tested on desktop or laptop machines if we can generate representative samples from large data sets. I describe a fast and memory efficient implementation of an on-line sampling method developed for tape drives 30 years ago. Focusing on genotype files, I test the performance of this technique on modern solid-state and spinning hard drives, and show that it performs well compared to a simple sampling scheme...
March 12, 2018: G3: Genes—Genomes—Genetics
Yiping Chen, Christiana Kartsonaki, Robert Clarke, Yu Guo, Canqing Yu, Zheng Bian, Qilian Jiang, Shanpeng Li, Junshi Chen, Liming Li, Zhengming Chen
BACKGROUND: Inadequate sleep duration and insomnia can affect both physical and mental health. There is limited evidence, however, on characteristics and correlates of sleep patterns and insomnia in urban and rural China. METHODS: This cross-sectional study, involving 512,891 adults aged 30-79 years from ten (five urban and five rural) diverse areas in China, recorded detailed information, using interviewer-administered laptop-based questionnaires, on sleep patterns (duration, daytime napping and snoring) and insomnia symptoms...
April 2018: Sleep Medicine
Nurten Terkes, Ferya Celik, Hicran Bektas
AIM: The use of technology is increasingly important in nursing education and practice. For this reason, it is necessary to determine the attitudes of nursing students towards technology. METHODS: This study was conducted with 508 nursing students. A personal information form that was prepared by the researchers and the Attitudes Toward Technology Scale were used as the data collection tools. RESULTS: The mean score that was obtained by the nursing students from the Attitudes Toward Technology Scale was 61...
March 11, 2018: Japan Journal of Nursing Science: JJNS
Muhammed Veli, Aydogan Ozcan
We present a cost-effective and portable platform based on contact lenses for non-invasively detecting Staphylococcus aureus, which is part of the human ocular microbiome and resides on the cornea and conjunctiva. Using Staphylococcus aureus-specific antibodies and a surface chemistry protocol that is compatible with human tear, contact lenses are designed to specifically capture Staphylococcus aureus. After the bacteria capture on the lens, and right before its imaging, the captured bacteria are tagged with surface-functionalized polystyrene microparticles...
March 9, 2018: ACS Nano
Henrik Finsberg, Ce Xi, Ju Le Tan, Liang Zhong, Martin Genet, Joakim Sundnes, Lik Chuan Lee, Samuel T Wall
Individually personalized computational models of heart mechanics can be used to estimate important physiological and clinically-relevant quantities that are difficult, if not impossible, to directly measure in the beating heart. Here we present a novel and efficient framework for creating patient-specific biventricular models using a gradient-based data assimilation method for evaluating regional myocardial contractility and estimating myofiber stress. These simulations can be performed on a regular laptop in less than two hours and produce excellent fit between measured and simulated volume and strain data through the entire cardiac cycle...
March 9, 2018: International Journal for Numerical Methods in Biomedical Engineering
I E Obi, A N Charles-Okoli, C C Agunwa, B I Omotowo, A C Ndu, O R Agwu-Umahi
Context: Learning in the medical school of the study university is still by the traditional face-to-face approach with minimal e-communication. Aim: This paper assesses student's perspectives of E-learning readiness, its predictors and presents a model for assessing them. Settings and Design: A descriptive cross-sectional study of medical students. Subjects and Methods: By proportional quota sampling 284 students responded to a semi-structured self-administered questionnaire adapted from literature...
March 2018: Nigerian Journal of Clinical Practice
R B Acton, L Vanderlee, C A Roberto, D Hammond
An increasing number of countries are developing front-of-package (FOP) labels; however, there is limited evidence examining the impact of specific design characteristics for these labels. The current study investigated consumer perceptions of several FOP label design characteristics, including potential differences among sociodemographic sub-groups. Two hundred and thirty-four participants aged 16 years or older completed nine label rating tasks on a laptop at a local shopping mall in Canada. The rating tasks asked participants to rate five primary design characteristics (border, background presence, background colour, 'caution' symbol and government attribution) on their noticeability, readability, believability and likelihood of changing their beverage choice...
March 3, 2018: Health Education Research
Cynthia Kratzke, Satya Rao, Ruben Marquez
Although adult health advocacy programs have been examined in communities, little is known about integrated adolescent health advocacy programs in high schools. The purpose of this study was to examine the health advocacy program impact and ethnic differences among high school students. Using a cross-sectional study, high school students participating in the school-based program completed evaluation surveys. The program domains included upstream causes of health, community assets, and public health advocacy...
March 6, 2018: Journal of Community Health
Jakob Jordan, Tammo Ippen, Moritz Helias, Itaru Kitayama, Mitsuhisa Sato, Jun Igarashi, Markus Diesmann, Susanne Kunkel
State-of-the-art software tools for neuronal network simulations scale to the largest computing systems available today and enable investigations of large-scale networks of up to 10 % of the human cortex at a resolution of individual neurons and synapses. Due to an upper limit on the number of incoming connections of a single neuron, network connectivity becomes extremely sparse at this scale. To manage computational costs, simulation software ultimately targeting the brain scale needs to fully exploit this sparsity...
2018: Frontiers in Neuroinformatics
Christopher Holmberg, Christina Berg, Jovanna Dahlgren, Lauren Lissner, John Eric Chaplin
This study aimed to explore experiences with online information regarding food, weight management, and health in a group of adolescents in treatment for obesity. Individual semi-structured interviews with 20 adolescents were conducted. Participants used a screen-recorded laptop to demonstrate their search procedures and online information sources. The transcribed interviews were categorized using qualitative content analysis. The adolescents described both encouraging and discouraging experiences. On one hand, they said that online forums could provide nutritious meal ideas and inspiration as well as social support for behavior change...
March 1, 2018: Health Informatics Journal
Mohamed Elgendi
In the digital medicine field, biosignals, such as those of an electrocardiogram (ECG), are collected regularly for screening and diagnosis, and there continues to be an increasingly substantial shift towards collecting long-term ECG signals for remote monitoring, e.g., in smart homes. ECG signal collection is quite simple and only requires the use of inexpensive sensors, an active Internet connection, and a mobile device that acts as the medium between the sensors and the Internet (e.g., a mobile phone or laptop)...
February 24, 2018: Diseases (Basel)
Adriana D Cruz, Maria Cn Castro, Marcelo F Aguiar, Ludmilla S Guimarães, Cinthya C Gomes
OBJECTIVES: To assess the radiographic appearances of the endodontic treatment in different room lighting conditions and image display devices. METHODS: After approval by Research Ethical Board, 20 images were obtained from blocks with one endodontically treated tooth. The 20 endodontic treatments were made in the laboratory, of those randomly selected, 10 teeth (50% of sample) received some quality defect in three parameters as apical limit, adaptation to root canal and homogeneity of the root canal filling material...
March 1, 2018: Dento Maxillo Facial Radiology
Wei Yu, Zheng Duan, Guang Zhang, Changhong Liu, Shoushan Fan
Carbon nanotubes (CNTs) and other related CNT-based materials with high thermal conductivity can be used as promising heat dissipation materials. Meanwhile, the miniaturization and high functionality of portable electronics, such as laptops and mobile phones, are achieved at the cost of overheating the high power-density components. The heat removal for hot spots occurring in a relatively narrow space requires simple and effective cooling methods. Here, an auxiliary passive cooling approach by the aid of a flat plate (aluminum-magnesium alloy) is investigated to accommodate heat dissipation in a narrow space...
February 26, 2018: Nano Letters
Sander W Keemink, Scott C Lowe, Janelle M P Pakan, Evelyn Dylda, Mark C W van Rossum, Nathalie L Rochefort
In vivo calcium imaging has become a method of choice to image neuronal population activity throughout the nervous system. These experiments generate large sequences of images. Their analysis is computationally intensive and typically involves motion correction, image segmentation into regions of interest (ROIs), and extraction of fluorescence traces from each ROI. Out of focus fluorescence from surrounding neuropil and other cells can strongly contaminate the signal assigned to a given ROI. In this study, we introduce the FISSA toolbox (Fast Image Signal Separation Analysis) for neuropil decontamination...
February 22, 2018: Scientific Reports
Aurélie Ruet, Bruno Brochet
BACKGROUND: Cognitive impairment (CI) is frequent in patients with multiple sclerosis (PwMS) and could negatively affect family social and vocational activities. Detecting CI is clinically relevant, so the emerging question is the strategy for assessing cognition in MS. OBJECTIVE: An update on cognitive assessment in PwMS with use of standard neuropsychological (NP) tests and ecological tools. RESULTS: The minimal cognitive assessment in MS should include at least NP tests assessing information processing speed (IPS) and verbal and visuospatial episodic memory...
February 17, 2018: Annals of Physical and Rehabilitation Medicine
Seyed Ali Reza Mortazavi, Seyed Mohammad Javad Mortazavi
Breast cancer is the most common malignancy among women, both in the developed and developing countries. Women with mutations in the BRCA1 and BRCA2 genes have an increased risk of breast and ovarian cancers. Recent studies show that short-wavelength visible light disturb the secretion of melatonin and causes circadian rhythm disruption. We have previously studied the health effects of exposure to different levels of radiofrequency electromagnetic fields (RF-EMFs) such as mobile phones, mobile base stations, mobile phone jammers, laptop computers, and radars...
February 2018: Iranian Journal of Basic Medical Sciences
Anshu Priya, Subrata Hait
Comprehensive characterization of printed circuit board (PCB) of end-of-life electrical and electronic equipment (EEE) is obligatory for prospective profitable beneficiation. In this study, beneficiation oriented comprehensive characterization of two brands of PCBs each of 16 end-of-life EEE was conducted in terms of their physicochemical characteristics with special emphasis on the content of 16 general elements, 2 precious metals and 15 rare earth elements (REEs). General elements and their highest weight percent composition found in different PCBs of the EEEs were Cu (23% in laptop), Al (6% in computer), Pb (15% in DVD player) and Ba (7% in TV)...
February 14, 2018: Waste Management
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