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https://www.readbyqxmd.com/read/29351671/a-novel-non-invasive-method-for-evaluating-electroencephalograms-on-laying-hens
#1
Krista N Eberle, Michael P Martin, Sanjay Shah, Ramon D Malheiros, Kimberly A Livingston, Kenneth E Anderson
The use of electroencephalograms (EEG) to study the avian brain relative to behavior was conducted as early as the 1960's. EEG readings, combined with visual cues, provide the ability to elucidate and correlate behaviors to neurological and physiological changes in a chicken. The use of EEG recordings in animal models require access to the brain to implant electrodes. Having the ability to observe EEG activity on sensible birds without surgical implantation could broaden the research in this area and give further insight related to the hen's state of awareness...
January 17, 2018: Poultry Science
https://www.readbyqxmd.com/read/29350513/racial-ethnic-variation-in-devices-used-to-access-patient-portals
#2
Eva Chang, Katherine Blondon, Courtney R Lyles, Luesa Jordan, James D Ralston
OBJECTIVES: We examined racial/ethnic variation in the devices used by patients to access medical records through an online patient portal. STUDY DESIGN: Retrospective, cross-sectional analysis. METHODS: Using data from 318,700 adults enrolled in an integrated delivery system between December 2012 and November 2013, we examined: 1) online patient portal use that directly engages the electronic health record and 2) portal use over desktops/laptops only, mobile devices only, or both device types...
January 1, 2018: American Journal of Managed Care
https://www.readbyqxmd.com/read/29342158/real-time-community-detection-in-full-social-networks-on-a-laptop
#3
Benjamin Paul Chamberlain, Josh Levy-Kramer, Clive Humby, Marc Peter Deisenroth
For a broad range of research and practical applications it is important to understand the allegiances, communities and structure of key players in society. One promising direction towards extracting this information is to exploit the rich relational data in digital social networks (the social graph). As global social networks (e.g., Facebook and Twitter) are very large, most approaches make use of distributed computing systems for this purpose. Distributing graph processing requires solving many difficult engineering problems, which has lead some researchers to look at single-machine solutions that are faster and easier to maintain...
2018: PloS One
https://www.readbyqxmd.com/read/29335233/internet-based-group-intervention-for-ovarian-cancer-survivors-feasibility-and-preliminary-results
#4
Ellen M Kinner, Jessica S Armer, Bonnie A McGregor, Jennifer Duffecy, Susan Leighton, Marya E Corden, Janine Gauthier Mullady, Frank J Penedo, Susan K Lutgendorf
BACKGROUND: Development of psychosocial group interventions for ovarian cancer survivors has been limited. Drawing from elements of cognitive-behavioral stress management (CBSM), mindfulness-based stress reduction (MBSR), and acceptance and commitment therapy (ACT), we developed and conducted preliminary testing of an Internet-based group intervention tailored specifically to meet the needs of ovarian cancer survivors. The Internet-based platform facilitated home delivery of the psychosocial intervention to a group of cancer survivors for whom attending face-to-face programs could be difficult given their physical limitations and the small number of ovarian cancer survivors at any one treatment site...
January 15, 2018: JMIR Cancer
https://www.readbyqxmd.com/read/29330118/using-the-ribodeblur-pipeline-to-recover-a-sites-from-yeast-ribosome-profiling-data
#5
Hao Wang, Carl Kingsford, C Joel McManus
Ribosome profiling has emerged as a powerful technique to study mRNA translation. Ribosome profiling has the potential to determine the relative quantities and locations of ribosomes on mRNA genome wide. Taking full advantage of this approach requires accurate measurement of ribosome locations. However, experimental inconsistencies often obscure the positional information encoded in ribosome profiling data. Here, we describe the Ribodeblur pipeline, a computational analysis tool that uses a maximum likelihood framework to infer ribosome positions from heterogeneous datasets...
January 9, 2018: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/29324929/our-solution-for-fusion-of-simultaneusly-acquired-whole-body-scintigrams-and-optical-images-as-usesful-tool-in-clinical-practice-in-patients-with-differentiated-thyroid-carcinomas-after-radioiodine-therapy-a-useful-tool-in-clinical-practice
#6
Milovan Matovic, Milica Jankovic, Marko Barjaktarovic, Marija Jeremic
OBJECTIVE: After radioiodine therapy of differentiated thyroid cancer (DTC) patients, whole body scintigraphy (WBS) is standard procedure before releasing the patient from the hospital. A common problem is the precise localization of regions where the iod-avide tissue is located. Sometimes is practically impossible to perform precise topographic localization of such regions. METHOD: In order to face this problem, we have developed a low-cost Vision-Fusion system for web-camera image acquisition simultaneously with routine scintigraphic whole body acquisition including the algorithm for fusion of images given from both cameras...
September 2017: Hellenic Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29315412/automated-pupillometry-and-detection-of-clinical-transtentorial-brain-herniation-a-case-series
#7
Alexander Papangelou, Elizabeth K Zink, Wan-Tsu W Chang, Anthony Frattalone, Daniel Gergen, Allan Gottschalk, Romergryko G Geocadin
Introduction: Transtentorial herniation (TTH) is a life-threatening neurologic condition that typically results from expansion of supratentorial mass lesions. A change in bedside pupillary examination is central to the clinical diagnosis of TTH. Materials and Methods: To quantify the changes in the pupillary examination that precede and accompany TTH and its treatment, we evaluated 12 episodes of herniation in three patients with supratentorial mass lesions using automated pupillometry (NeurOptics, Inc...
January 5, 2018: Military Medicine
https://www.readbyqxmd.com/read/29301168/design-and-development-of-a-novel-distance-learning-telementoring-system-using-off-the-shelf-materials-and-software
#8
James C Rosser, Jeffrey P Fleming, Timothy B Legare, Katherine M Choi, Jamie Nakagiri, Elliot Griffith
OBJECTIVE: To design and develop a distance learning (DL) system for the transference of laparoscopic surgery knowledge and skill constructed from off-the-shelf materials and commercially available software. INTRODUCTION: Minimally invasive surgery offers significant benefits over traditional surgical procedures, but adoption rates for many procedures are low. Skill and confidence deficits are two of the culprits. DL combined with simulation training and telementoring may address these issues with scale...
December 22, 2017: Surgical Technology International
https://www.readbyqxmd.com/read/29286470/nanopore-dna-sequencing-for-metagenomic-soil-analysis
#9
P J Cummings, J Olszewicz, K M Obom
This article describes the steps for construction of a DNA library from soil, preparation and use of the nanopore flow cell, and analysis of the DNA sequences identified using computer software. Nanopore DNA sequencing is a flexible technique that allows for rapid microbial genome sequencing to identify bacterial and viral species, to characterize bacterial strains, and to detect genetic mutations that confer resistance to antibiotics. The advantages of nanopore sequencing (NS) for life sciences include its low complexity, reduced cost, and rapid real-time sequencing of purified genomic DNA, PCR amplicons, cDNA samples, or RNA...
December 14, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29280402/computer-users-ergonomics-and-quality-of-life%C3%A2-%C3%A2-evidence-from-a-developing-country
#10
Ishfaq Ahmed, Muhammad Zeeshan Shaukat
This study is aimed at investigating the quality of workplace ergonomics at various Pakistani organizations and quality of life of computer users working in these organizations. Two hundred and thirty-five computer users (only those employees who have to do most of their job tasks on computer or laptop, and at their office) responded by filling the questionnaire covering questions on workplace ergonomics and quality of life. Findings of the study revealed the ergonomics at those organizations was poor and unfavourable...
December 27, 2017: International Journal of Injury Control and Safety Promotion
https://www.readbyqxmd.com/read/29246107/canary-an-atomic-pipeline-for-clinical-amplicon-assays
#11
Kenneth D Doig, Jason Ellul, Andrew Fellowes, Ella R Thompson, Georgina Ryland, Piers Blombery, Anthony T Papenfuss, Stephen B Fox
BACKGROUND: High throughput sequencing requires bioinformatics pipelines to process large volumes of data into meaningful variants that can be translated into a clinical report. These pipelines often suffer from a number of shortcomings: they lack robustness and have many components written in multiple languages, each with a variety of resource requirements. Pipeline components must be linked together with a workflow system to achieve the processing of FASTQ files through to a VCF file of variants...
December 15, 2017: BMC Bioinformatics
https://www.readbyqxmd.com/read/29244002/higher-recall-in-metagenomic-sequence-classification-exploiting-overlapping-reads
#12
Samuele Girotto, Matteo Comin, Cinzia Pizzi
BACKGROUND: In recent years several different fields, such as ecology, medicine and microbiology, have experienced an unprecedented development due to the possibility of direct sequencing of microbioimic samples. Among problems that researchers in the field have to deal with, taxonomic classification of metagenomic reads is one of the most challenging. State of the art methods classify single reads with almost 100% precision. However, very often, the performance in terms of recall falls at about 50%...
December 6, 2017: BMC Genomics
https://www.readbyqxmd.com/read/29226202/interobserver-variability-of-radiographic-assessment-using-a-mobile-messaging-application-as-a-teleconsultation-tool
#13
Sezai Özkan, Jos J Mellema, David Ring, Neal C Chen
Background: To examine whether interobserver reliability, decision-making, and confidence in decision-making in the treatment of distal radius fractures changes if radiographs are viewed on a messenger application on a mobile phone compared to a standard DICOM viewer. Methods: Radiographs of distal radius fractures were presented to surgeons on either a smart phone using a mobile messenger application or a laptop using a DICOM viewer application. Twenty observers participated: 10 (50%) were randomly assigned to the DICOM viewer group and 10 (50%) to the mobile messenger group...
September 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/29215151/brain-connectivity-in-children-is-increased-by-the-time-they-spend-reading-books-and-decreased-by-the-length-of-exposure-to-screen-based-media
#14
Tzipi Horowitz-Kraus, John S Hutton
AIM: This study compared the time spent using screen-based media or reading on the functional connectivity of the reading-related brain regions in children aged 8-12. METHODS: We recruited 19 healthy American children from a private school in Cincinnati, USA, in 2015-6 after advertising the study to parents. The parents completed surveys on how many hours their children spent on independent reading and screen-based media time, including smartphones, tablets, desktop or laptop computers and television...
December 7, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29214149/measurements-of-radiofrequency-radiation-with-a-body-borne-exposimeter-in-swedish-schools-with-wi-fi
#15
Lena K Hedendahl, Michael Carlberg, Tarmo Koppel, Lennart Hardell
Introduction: Wireless access to the Internet is now commonly used in schools. Many schools give each student their own laptop and utilize the laptops and wireless fidelity (Wi-Fi) connection for educational purposes. Most children also bring their own mobile phones to school. Since children are obliged by law to attend school, a safe environment is important. Lately, it has been discussed if radiofrequency (RF) radiation can have long-term adverse effects on children's health. Method: This study conducted exposimetric measurements in schools to assess RF emissions in the classroom by measuring the teachers' RF exposure in order to approximate the children's exposure...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29203653/rapid-diagnostic-testing-platform-for-iron-and-vitamin-a-deficiency
#16
Zhengda Lu, Dakota O'Dell, Balaji Srinivasan, Elizabeth Rey, Ruisheng Wang, Sasank Vemulapati, Saurabh Mehta, David Erickson
Micronutrient deficiencies such as those of vitamin A and iron affect a third of the world's population with consequences such as night blindness, higher child mortality, anemia, poor pregnancy outcomes, and reduced work capacity. Many efforts to prevent or treat these deficiencies are hampered by the lack of adequate, accessible, and affordable diagnostic methods that can enable better targeting of interventions. In this work, we demonstrate a rapid diagnostic test and mobile enabled platform for simultaneously quantifying iron (ferritin), vitamin A (retinol-binding protein), and inflammation (C-reactive protein) status...
December 19, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29193654/technology-experience-of-solid-organ-transplant-patients-and-their-overall-willingness-to-use-interactive-health-technology
#17
Jasper M M Vanhoof, Bert Vandenberghe, David Geerts, Pieter Philippaerts, Patrick De Mazière, Annette DeVito Dabbs, Sabina De Geest, Fabienne Dobbels
BACKGROUND: The use of interactive health technology (IHT) is a promising pathway to tackle self-management problems experienced by many chronically ill patients, including solid organ transplant (Tx) patients. Yet, to ensure that the IHT is accepted and used, a human-centered design process is needed, actively involving end users in all steps of the development process. A first critical, predevelopment step involves understanding end users' characteristics. This study therefore aims to (a) select an IHT platform to deliver a self-management support intervention most closely related to Tx patients' current use of information and communication technologies (ICTs), (b) understand Tx patients' overall willingness to use IHT for self-management support, and investigate associations with relevant technology acceptance variables, and (c) explore Tx patients' views on potential IHT features...
November 28, 2017: Journal of Nursing Scholarship
https://www.readbyqxmd.com/read/29188309/optimization-of-ultrahigh-speed-multiplex-pcr-for-forensic-analysis
#18
Georgiana Gibson-Daw, Karin Crenshaw, Bruce McCord
In this paper, we demonstrate the design and optimization of an ultrafast PCR amplification technique, used with a seven-locus multiplex that is compatible with conventional capillary electrophoresis systems as well as newer microfluidic chip devices. The procedure involves the use of a high-speed polymerase and a rapid cycling protocol to permit multiplex PCR amplification of forensic short tandem repeat loci in 6.5 min. We describe the selection and optimization of master mix reagents such as enzyme, buffer, MgCl2, and dNTPs, as well as primer ratios, total volume, and cycle conditions, in order to get the best profile in the shortest time possible...
November 29, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29186333/fun-a-framework-for-interactive-visualizations-of-large-high-dimensional-datasets-on-the-web
#19
Daniel Probst, Jean-Louis Reymond
Motivation: During the past decade, big data has become a major tool in scientific endeavors. While statistical methods and algorithms are well-suited for analyzing and summarizing enormous amounts of data, the results do not allow for a visual inspection of the entire data. Current scientific software, including R packages and Python libraries such as ggplot2, matplotlib, and plot.ly, do not support interactive visualizations of datasets exceeding 100,000 data points on the web. Other solutions enable the web-based visualization of big data only through data reduction or statistical representations...
November 24, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29160772/crystal-identification-for-a-dual-layer-offset-lyso-based-pet-system-via-lu-176-background-radiation-and-mean-shift-algorithm
#20
Qingyang Wei, Tianyu Ma, Tianpeng Xu, Ming Zeng, Yu Gu, Tiantian Dai, Yaqiang Liu
Modern positron emission tomography (PET) detectors are made from pixelated scintillation crystal arrays and readout by Anger logic. The interaction position of the gamma-ray should be assigned to a crystal using a crystal position map or look-up table. Crystal identification is a critical procedure for pixelated PET systems. In this paper, we propose a novel crystal identification method for a dual-layer-offset LYSO based animal PET system via Lu-176 background radiation and mean shift algorithm. Single photon event data of the Lu-176 background radiation are acquired in list-mode for 3 hours to generate a single photon flood map (SPFM)...
November 21, 2017: Physics in Medicine and Biology
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