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https://www.readbyqxmd.com/read/27930676/stochastic-simulation-service-bridging-the-gap-between-the-computational-expert-and-the-biologist
#1
Brian Drawert, Andreas Hellander, Ben Bales, Debjani Banerjee, Giovanni Bellesia, Bernie J Daigle, Geoffrey Douglas, Mengyuan Gu, Anand Gupta, Stefan Hellander, Chris Horuk, Dibyendu Nath, Aviral Takkar, Sheng Wu, Per Lötstedt, Chandra Krintz, Linda R Petzold
We present StochSS: Stochastic Simulation as a Service, an integrated development environment for modeling and simulation of both deterministic and discrete stochastic biochemical systems in up to three dimensions. An easy to use graphical user interface enables researchers to quickly develop and simulate a biological model on a desktop or laptop, which can then be expanded to incorporate increasing levels of complexity. StochSS features state-of-the-art simulation engines. As the demand for computational power increases, StochSS can seamlessly scale computing resources in the cloud...
December 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27927083/measurement-of-peripheral-vision-reaction-time-identifies-white-matter-disruption-in-patients-with-mild-traumatic-brain-injury
#2
Kyle B Womack, Christopher Paliotta, Jeremy F Strain, Johnson S Ho, Yosef S Skolnick, William W Lytton, L Christine Turtzo, Roderick McColl, Ramon Diaz-Arrastia, Peter Bergold
This study examined whether peripheral vision reaction time (PVRT) in patients with mild traumatic brain injury (mTBI) correlate with white matter abnormalities in centroaxial structures and impairments in neuropsychological testing. Within 24 hours after mTBI, crossed reaction times (CRT), uncrossed reaction times (URT) and crossed-uncrossed difference (CUD) were measured in 23 patients using a laptop computer that displayed visual stimuli predominantly to either the left or right visual field of the retina...
December 7, 2016: Journal of Neurotrauma
https://www.readbyqxmd.com/read/27919439/associations-between-physical-activity-and-semen-quality-in-young-healthy-men
#3
Paweł Jóźków, Marek Mędraś, Felicja Lwow, Aleksandra Zagrodna, Małgorzata Słowińska-Lisowska
OBJECTIVE: To evaluate whether the level of everyday physical activity is associated with semen quality in young men. DESIGN: Cross-sectional study. SETTING: Universities, clubs, and societies. PATIENT(S): Young healthy men (aged 18-35 years) with unknown fertility (n = 177). INTERVENTIONS(S): Collection of data on medical history, lifestyle factors (physical activity, nutrition, addictions), and environmental threats (exposure of gonads to cellular phones, laptops)...
December 2, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27917792/potential-beneficial-effects-of-foot-bathing-on-cardiac-rhythm
#4
Duygu Aydin, Siti Sugih Hartiningsih, Melike Gokce Izgi, Sevgi Bay, Kubra Unlu, Meryem Ozlem Tatar, Ayse Melike Alparslan, Mohammed Ozeri, Senol Dane
PURPOSE: Foot bathing therapy is a simple technique that induces sensations of comfort and relaxation. The aim of this study was to examine the effect of foot bathing therapy on heart rate variability (HRV) parameters in a healthy population. METHODS: Participants were twenty healthy female subjects (median age=20.67 years, SD=1.04). The recording ECG was applied for 5 minutes before and for 5 minutes after foot bathing therapy of 10 minutes. Subjects rested for 10 minutes without recording ECG in order to stabilize autonomic parameters...
December 1, 2016: Clinical and Investigative Medicine. Médecine Clinique et Experimentale
https://www.readbyqxmd.com/read/27913331/lamb-wave-multitouch-ultrasonic-touchscreen
#5
Kamyar Firouzi, Amin Nikoozadeh, Thomas E Carver, Butrus Pierre T Khuri-Yakub
Touchscreen sensors are widely used in many devices such as smart phones, tablets, and laptops with diverse applications. We present the design, analysis, and implementation of an ultrasonic touchscreen system that utilizes the interaction of transient Lamb waves with objects in contact with the screen. It attempts to improve on the existing ultrasound technologies, with the potential of addressing some of the weaknesses of the dominant technologies, such as the capacitive or resistive ones. Compared with the existing ultrasonic and acoustic modalities, among other advantages, it provides the capability of detecting several simultaneous touch points and also a more robust performance...
December 2016: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/27912979/measuring-performance-in-the-interpretation-of-chest-radiographs-a-pilot-study
#6
Y Chen, J J James, L Dong, A G Gale
AIM: To develop a system to assess the image interpretation performance of radiologists in identifying signs of malignancy on chest radiographs. MATERIALS AND METHODS: A test set of 30 chest radiographs was chosen by an experienced radiologist consisting of 11 normal and 19 abnormal cases. The malignant cases all had biopsy-proven pathology; the normal and benign cases all had at least 2 years of imaging follow-up. Fourteen radiologists with a range of experiences were recruited...
November 29, 2016: Clinical Radiology
https://www.readbyqxmd.com/read/27909536/screening-for-atrial-fibrillation-in-the-community-using-a-novel-ecg-recorder
#7
Irma Battipaglia Md, Katrina Gilbert BSc, Andrew J Hogarth Md PhD, Muzahir H Tayebjee Md
Aims: MyDiagnostick (MDK) is a novel portable ECG recorder. We conducted this study to evaluate its role in screening for atrial fibrillation (AF). Methods: The device is a cylindrical rod with metallic electrodes at both ends recording electrocardiogram (ECG) when both electrodes are held. Individuals were requested to hold the device for approximately 15 s, the device was then connected to a laptop (with proprietary software downloaded) and analysed. Anonymised ECGs were stored for further analysis. A total of 855 ECGs were recorded and analysed offline by two arrhythmia specialists assessing ECG quality, in particular the level of noise...
August 2016: Journal of Atrial Fibrillation
https://www.readbyqxmd.com/read/27906071/are-digital-interventions-for-smoking-cessation-in-pregnancy-effective-a-systematic-review-protocol
#8
Sarah Ellen Griffiths, Katherine E Brown, Emily Anne Fulton, Ildiko Tombor, Felix Naughton
BACKGROUND: Behavioural support for smoking cessation in pregnancy can be effective; however, many pregnant women face barriers to seeking support to stop smoking. Some digital interventions have been found to be effective for smoking cessation in the general population and may be effective for supporting cessation in pregnancy due to their flexibility and the potential for personalisation. To date, there is limited evidence of the effectiveness of digital interventions for smoking cessation in pregnancy...
December 1, 2016: Systematic Reviews
https://www.readbyqxmd.com/read/27903857/a-hyperpigmented-reticular-rash-in-a-patient-on-peritoneal-dialysis
#9
Andrew M South, Milene K Crispin, Ann L Marqueling, Scott M Sutherland
Chronically ill patients often develop uncommon exam findings. A 16-year-old female with end-stage renal disease secondary to immune complex-mediated glomerulonephritis on peritoneal dialysis (PD) developed a pruritic, hyperpigmented reticular rash on her abdomen, sparing the PD catheter insertion site. The rash appeared approximately 6 weeks after initiating PD. She used a heating pad nightly during PD for dialysis drain pain. Testing for systemic and autoimmune disease was negative. She was referred to dermatology, where the diagnosis of erythema ab igne (EAI), a well-described but less well-known hyperpigmented reticular cutaneous eruption caused by chronic exposure to low levels of infrared heat, was confirmed...
November 2016: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/27900418/rapid-microfluidic-analysis-of-a-y-str-multiplex-for-screening-of-forensic-samples
#10
Georgiana Gibson-Daw, Patricia Albani, Marcus Gassmann, Bruce McCord
In this paper, we demonstrate a rapid analysis procedure for use with a small set of rapidly mutating Y chromosomal short tandem repeat (Y-STR) loci that combines both rapid polymerase chain reaction (PCR) and microfluidic separation elements. The procedure involves a high-speed polymerase and a rapid cycling protocol to permit PCR amplification in 16 min. The resultant amplified sample is next analysed using a short 1.8-cm microfluidic electrophoresis system that permits a four-locus Y-STR genotype to be produced in 80 s...
November 30, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/27895967/medical-representatives-intention-to-use-information-technology-in-pharmaceutical-marketing
#11
Eun-Seon Kwak, Hyejung Chang
OBJECTIVES: Electronic detailing (e-detailing), the use of electronic devices to facilitate sales presentations to physicians, has been adopted and expanded in the pharmaceutical industry. To maximize the potential outcome of e-detailing, it is important to understand medical representatives (MRs)' behavior and attitude to e-detailing. This study investigates how information technology devices such as laptop computers and tablet PCs are utilized in pharmaceutical marketing, and it analyzes the factors influencing MRs' intention to use devices...
October 2016: Healthcare Informatics Research
https://www.readbyqxmd.com/read/27890594/an-investigation-of-trends-in-precious-metal-and-copper-content-of-ram-modules-in-weee-implications-for-long-term-recycling-potential
#12
Rhys Gareth Charles, Peter Douglas, Ingrid Liv Hallin, Ian Matthews, Gareth Liversage
Precious metal (PM) and copper content of dynamic-RAM modules placed on the market during 1991-2008 has been analysed by AAS following comminution and acid digestion. Linear regression analysis of compositional data ordered according to sample chronology was used to identify historic temporal trends in module composition resulting from changes in manufacturing practices, and to project future trends for use in more accurate assessment of future recycling potential. DRAM was found to be 'high grade' waste with: stable levels of gold and silver over time; 80% reduction in palladium content during 1991-2008; and 0...
November 24, 2016: Waste Management
https://www.readbyqxmd.com/read/27864814/nodegame-real-time-synchronous-online-experiments-in-the-browser
#13
REVIEW
Stefano Balietti
nodeGame is a free, open-source JavaScript/ HTML5 framework for conducting synchronous experiments online and in the lab directly in the browser window. It is specifically designed to support behavioral research along three dimensions: (i) larger group sizes, (ii) real-time (but also discrete time) experiments, and (iii) batches of simultaneous experiments. nodeGame has a modular source code, and defines an API (application programming interface) through which experimenters can create new strategic environments and configure the platform...
November 18, 2016: Behavior Research Methods
https://www.readbyqxmd.com/read/27853580/multispeq-beta-a-tool-for-large-scale-plant-phenotyping-connected-to-the-open-photosynq-network
#14
Sebastian Kuhlgert, Greg Austic, Robert Zegarac, Isaac Osei-Bonsu, Donghee Hoh, Martin I Chilvers, Mitchell G Roth, Kevin Bi, Dan TerAvest, Prabode Weebadde, David M Kramer
Large-scale high-throughput plant phenotyping (sometimes called phenomics) is becoming increasingly important in plant biology and agriculture and is essential to cutting-edge plant breeding and management approaches needed to meet the food and fuel needs for the next century. Currently, the application of these approaches is severely limited by the availability of appropriate instrumentation and by the ability to communicate experimental protocols, results and analyses. To address these issues, we have developed a low-cost, yet sophisticated open-source scientific instrument designed to enable communities of researchers, plant breeders, educators, farmers and citizen scientists to collect high-quality field data on a large scale...
October 2016: Royal Society Open Science
https://www.readbyqxmd.com/read/27833922/the-feasibility-of-health-trainer-improved-patient-self-management-in-patients-with-low-health-literacy-and-poorly-controlled-diabetes-a-pilot-randomised-controlled-trial
#15
Joanne Protheroe, Trishna Rathod, Bernadette Bartlam, Gillian Rowlands, Gerry Richardson, David Reeves
Type 2 diabetes mellitus is most prevalent in deprived communities and patients with low health literacy have worse glycaemic control and higher rates of diabetic complications. However, recruitment from this patient population into intervention trials is highly challenging. We conducted a study to explore the feasibility of recruitment and to assess the effect of a lay health trainer intervention, in patients with low health literacy and poorly controlled diabetes from a socioeconomically disadvantaged population, compared with usual care...
2016: Journal of Diabetes Research
https://www.readbyqxmd.com/read/27822404/evolution-of-technology-in-teaching-blackboard-and-beyond-in-medical-education
#16
REVIEW
Jayakumary Muttappallymyalil, Susirith Mendis, Lisha Jenny John, Nisha Shanthakumari, Jayadevan Sreedharan, Rizwana B Shaikh
TEACHING AND LEARNING: the passing of knowledge from one generation to another - has been in existence from the earliest times of human civilization. It began in 1801, with a large piece of slate hung on the wall in a school in Scotland to provide information to a large audience at one time. In the US by mid-19th century, every class room had a blackboard to teach students. The modern version of the blackboard is either green or brown board. This was introduced in late 1960s. The whiteboards came into use during the late 1980s...
October 2016: Nepal journal of epidemiology
https://www.readbyqxmd.com/read/27812170/how-do-nursing-students-use-digital-tools-during-lectures
#17
Isabelle Sebri, Jean-Claude Bartier, Thierry Pelaccia
OBJECTIVES: Teachers often wonder what students are doing during lectures, behind their computers, mobile phones and other digital tools. This study aimed to document the type of tools used during lectures by nursing students and what they do with them. METHODS: We carried out a descriptive, prospective, multicentre study including 1446 nursing students in Alsace (France). The students filled in an anonymous questionnaire at the end of a lesson they had just attended...
2016: PloS One
https://www.readbyqxmd.com/read/27805622/mapping-of-radio-frequency-electromagnetic-field-exposure-levels-in-outdoor-environment-and-comparing-with-reference-levels-for-general-public-health
#18
Mustafa Cansiz, Teymuraz Abbasov, M Bahattin Kurt, A Recai Celik
In this study, radio frequency electromagnetic field exposure levels were measured on the main streets in the city center of Diyarbakır, Turkey. Measured electric field levels were plotted on satellite imagery of Diyarbakır and were compared with exposure guidelines published by the International Commission on Non-Ionizing Radiation Protection (ICNIRP). Exposure measurements were performed in dense urban, urban and suburban areas each day for 7 consecutive days. The measurement system consisted of high precision and portable spectrum analyzer, three-axis electric field antenna, connection cable and a laptop which was used to record the measurement samples as a data logger...
November 2, 2016: Journal of Exposure Science & Environmental Epidemiology
https://www.readbyqxmd.com/read/27800077/cholera-public-health-surveillance-in-the-republic-of-cameroon-opportunities-and-challenges
#19
Moise Chi Ngwa, Song Liang, Leonard Mbam Mbam, Arabi Mouhaman, Andrew Teboh, Kaousseri Brekmo, Onana Mevoula, John Glenn Morris
INTRODUCTION: In Cameroon, cholera has periodically resurfaced since it was first reported in 1971. In 2003, Cameroon adapted the Integrated Disease Surveillance and Response (IDSR) strategy to strengthen surveillance in the country. This study was an in-depth description and assessment of the structure, core and support functions, and attributes of the current cholera surveillance system in Cameroon. It also discussed its strengths and challenges with hope that lessons learned could improve the system in Cameroon and in other countries in Africa implementing the IDSR strategy...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27797091/preliminary-validation-study-of-the-3-min-wrist-worn-psychomotor-vigilance-test
#20
Panagiotis Matsangas, Nita Lewis Shattuck, Stephanie Brown
The 10-min psychomotor vigilance test (PVT) is a widely used tool to assess behavioral alertness. In operational environments, however, the 3-min version of the PVT is more practicable. Under controlled laboratory conditions, we compared performance on the 3-min PVT on a wrist-worn device with the 3-min PVT on a laptop computer. We conducted two repeated measures experiments (72 participants) to assess the effects of PVT device type (laptop or wrist-worn), backlight on the wrist-worn device (on or off), ambient light (low or normal levels), and interstimulus interval (ISI)...
October 28, 2016: Behavior Research Methods
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