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chronic regional pain syndrome

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https://www.readbyqxmd.com/read/29214172/migraine-and-complex-regional-pain-syndrome-a-case-referent-clinical-study
#1
Yohannes W Woldeamanuel, Corinne Cooley, Katharine Foley-Saldena, Robert P Cowan
We studied clinical phenotype differences between migraineurs with CRPS (Mig + CRPS) and those without (Mig - CRPS). Mig + CRPS cases and Mig - CRPS referents aged ≥18 years were enrolled. Diagnosis was made in accordance with International Classification of Headache Disorders-3 beta (ICHD-3 beta) for migraine and Budapest Criteria for CRPS. Migraines both with and without aura were included. A total of 70 Mig + CRPS cases (13% males, mean age 48 years) and 80 Mig - CRPS referents (17% males, mean age 51 years) were included...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29209138/effects-of-glutathione-on-mechanical-allodynia-and-central-sensitization-in-chronic-postischemic-pain-rats
#2
Jinseok Yeo, Hoon Jung, Hyerim Lee
Background: The chronic postischemia pain (CPIP) model is an animal model using ischemia/reperfusion injury that mimics the symptoms of complex regional pain syndrome type I. Glutathione (GSH) prevents ischemia/reperfusion injury by scavenging free radicals. We conducted this study to investigate the protective effect of GSH in CPIP rats via changes of mechanical allodynia and phospholyration of the N-methyl-D-aspartate receptor subunit GluN1. Methods: We divided 45 rats into 5 groups: sham, CPIP, CPIP + GSH 100 mg/kg, CPIP + GSH 200 mg/kg, and CPIP + GSH 500 mg/kg...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/29201643/relationships-between-brain-metabolite-levels-functional-connectivity-and-negative-mood-in-urologic-chronic-pelvic-pain-syndrome-patients-compared-to-controls-a-mapp-research-network-study
#3
Daniel E Harper, Eric Ichesco, Andrew Schrepf, Megan Halvorson, Tudor Puiu, Daniel J Clauw, Richard E Harris, Steven E Harte
Until recently, the predominant pathology of chronic pelvic pain conditions was thought to reside in the peripheral tissues. However, mounting evidence from neuroimaging studies suggests an important role of the central nervous system in the pathogenesis of these conditions. In the present cross-sectional study, proton magnetic resonance spectroscopy (1H-MRS) of the brain was conducted in female patients with urologic chronic pelvic pain syndrome (UCPPS) to determine if they exhibit abnormal concentrations of brain metabolites (e...
2018: NeuroImage: Clinical
https://www.readbyqxmd.com/read/29200885/treatment-of-complex-regional-pain-syndrome-using-free-flap-surgery-a-case-report
#4
Dong-Kyo Seo, Ho-Seong Lee, Joon Pio Hong, Jeong-Ho Seo, Jin Woo Shin
Complex regional pain syndrome is a chronic progressive illness with sensory, autonomic, trophic, and motor abnormalities. Treatment is difficult and controversial. We report the results of free-flap and vein wrapping of the superficial peroneal nerve surgery to treat complex regional pain syndrome.
2017: Journal of Pain Research
https://www.readbyqxmd.com/read/29199542/medication-use-among-pediatric-patients-with-chronic-musculoskeletal-pain-syndromes-at-initial-pain-clinic-evaluation
#5
Jessica W Guite, David D Sherry, Esther W Jarvis, Margaret O Lewen, Sarosh Khan, Francis Wickham Kraemer
AIM: To characterize medication use by adolescents with chronic musculoskeletal pain syndromes before an initial multidisciplinary clinic visit. PATIENTS & METHODS: A cross-sectional sample of 120 adolescents and parents reported on standardized assessment measures, with medication use data extracted from the medical chart and categorized. RESULTS: On average, 3.2 medications were reported; 70% used more than one pain-specific medication including opioids (17%), nonopioids (31%), psychotropics/neuropathics (45%) and other medications (13%)...
December 4, 2017: Pain Management
https://www.readbyqxmd.com/read/29196182/peripheral-5-ht3-mediates-mirror-image-pain-by-a-cross-talk-with-acid-sensing-ion-channel-3
#6
Yeu-Shiuan Su, Hao-Ruei Mei, Chun-Hung Wang, Wei-Hsin Sun
Mirror-image pain (MIP), which occurs along with complex regional pain syndrome, rheumatoid arthritis and chronic migraine, is characterized by increased pain sensitivity of healthy body regions other than the actual injured or inflamed sites. A high level of peripheral inflammation may activate central or peripheral glia, triggering mirror-image pain. However, which receptors mediate inflammatory signals to contribute glial activation remains unclear. Intraplantarly injecting mice with 5-hydroxytryptamine (5-HT) or acidic buffer (proton) caused only unilateral hyperalgesia, but co-injection of 5-HT/acid induced bilateral hyperalgesia (MIP)...
November 28, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29169795/paravertebral-block-for-thoracic-surgery
#7
REVIEW
Francine D'Ercole, Harendra Arora, Priya A Kumar
Local anesthetic injected into a wedge-shaped space lateral to the spinal nerves as they emerge from the intervertebral foramina produces somatosensory and sympathetic nerve blockade effective for anesthesia and for managing pain of unilateral origin from the chest and abdomen. Paravertebral blockade (PVB) is versatile and may be applied unilaterally or bilaterally. Unlike thoracic epidural, the PVB technique may be used to avoid contralateral sympathectomy, thereby minimizing hypotension and leading to better preservation of blood pressure...
October 4, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29163341/effects-of-transcranial-direct-current-stimulation-transcranial-pulsed-current-stimulation-and-their-combination-on-brain-oscillations-in-patients-with-chronic-visceral-pain-a-pilot-crossover-randomized-controlled-study
#8
Aurore Thibaut, Cristina Russo, Aura Maria Hurtado-Puerto, Jorge Leon Morales-Quezada, Alícia Deitos, John Christopher Petrozza, Steven Freedman, Felipe Fregni
Objective: Chronic visceral pain (CVP) syndromes are persistently painful disorders with a remarkable lack of effective treatment options. This study aimed at evaluating the effects of different neuromodulation techniques in patients with CVP on cortical activity, through electreocephalography (EEG) and on pain perception, through clinical tests. Design: A pilot crossover randomized controlled study. Settings: Out-patient. Subjects: Adults with CVP (>3 months)...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29145330/pathologic-femoral-fracture-due-to-tenofovir-induced-fanconi-syndrome-in-patient-with-chronic-hepatitis-b-a-case-report
#9
You-Sung Suh, Dong-Il Chun, Sung-Woo Choi, Hwan-Woong Lee, Jae-Hwi Nho, Soon-Hyo Kwon, Jae-Ho Cho, Sung Hun Won
RATIONALE: We report a case of a hepatitis B virus (HBV)-positive patient with preexisting bone disease who developed tenofovir-induced Fanconi syndrome and subsequently sustained pathologic fracture. To our best knowledge, this is the first report in the English literature about pathologic femoral fracture due to tenofovir-induced Fanconi syndrome in patient with chronic hepatitis B (CHB). The present report describes detailed our experience with the diagnosis of pathologic femoral fracture due to tenofovir-induced Fanconi syndrome and treatment...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29135531/recurrent-subanesthetic-ketamine-infusions-for-complex-regional-pain-syndrome-leading-to-biliary-dilation-jaundice-and-cholangitis-a-case-report
#10
Nathan A Hewitt, Peter Cox
Complex regional pain syndrome is a chronic pain condition that may be resistant to many treatment modalities. Ketamine infusions have demonstrated some promising results, though their use may be associated with a number of adverse effects limiting their widespread applicability. Hepatotoxicity and cholangiopathy have been described in chronic ketamine abuse, though rarely in therapeutic use. We report the impact of recurrent short subanesthetic ketamine infusions for the treatment of complex regional pain syndrome resulting in biliary dilation, jaundice, and cholangitis...
November 9, 2017: A & A Case Reports
https://www.readbyqxmd.com/read/29106051/treatment-of-chronic-refractory-neuropathic-pelvic-pain-with-high-frequency-10-kilohertz-spinal-cord-stimulation
#11
Thomas Simopoulos, Jason Yong, Jatinder S Gill
Chronic non-malignant pain perceived in the pelvic region commonly presents as a diagnostic challenge and is often difficult to manage. Treatment options are delayed as well as limited. The prevalence in the United States and the United Kingdom has been estimated to range from 14.7 % to 24% respectively (1, 2). Common chronic pelvic pain syndromes include interstitial cystitis, chronic prostatitis, coccygodynia, vulvodynia, chronic proctalgia, and pudendal neuralgia. This article is protected by copyright. All rights reserved...
November 6, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29097026/diagnosis-and-treatment-of-movement-system-impairment-syndromes
#12
REVIEW
Shirley Sahrmann, Daniel C Azevedo, Linda Van Dillen
BACKGROUND: Diagnoses and treatments based on movement system impairment syndromes were developed to guide physical therapy treatment. OBJECTIVES: This masterclass aims to describe the concepts on that are the basis of the syndromes and treatment and to provide the current research on movement system impairment syndromes. RESULTS: The conceptual basis of the movement system impairment syndromes is that sustained alignment in a non-ideal position and repeated movements in a specific direction are thought to be associated with several musculoskeletal conditions...
November 2017: Brazilian Journal of Physical Therapy
https://www.readbyqxmd.com/read/29080932/treatment-of-drug-resistant-fibromyalgia-symptoms-using-high-intensity-laser-therapy-a-case-based-review
#13
REVIEW
Paul F White, Jason Zafereo, Ofelia Loani Elvir-Lazo, Hector Hernandez
Fibromyalgia is a chronic musculoskeletal condition characterized by widespread pain in the body and is associated with tender points at the shoulder, back and hip regions. A wide variety of pharmacologic drugs and dietary supplements have been used with limited success in treating the musculoskeletal pain. Early clinical studies with low level laser therapy (LLLT) alone or in combination with drugs commonly used to treat fibromyalgia suggested that LLLT may be effective in reducing musculoskeletal pain and stiffness, as well as the number of tender locations...
October 28, 2017: Rheumatology International
https://www.readbyqxmd.com/read/29059243/muscle-oxygenation-in-type-1-diabetic-and-non-diabetic-patients-with-and-without-chronic-compartment-syndrome
#14
Patrik Gustafsson, Albert G Crenshaw, David Edmundsson, Göran Toolanen, Sead Crnalic
BACKGROUND: Type 1 diabetic patients and non-diabetic patients were referred for evaluation for chronic exertional compartment syndrome (CECS) based on clinical examination and complaints of activity-related leg pain in the region of the tibialis anterior muscle. Previous studies using near-infrared spectroscopy (NIRS) showed greater deoxygenation during exercise for CECS patients versus healthy controls; however, this comparison has not been done for diabetic CECS patients. METHODS: We used NIRS to test for differences in oxygenation kinetics for Type 1 diabetic patients diagnosed with (CECS-diabetics, n = 9) versus diabetic patients without (CON-diabetics, n = 10) leg anterior chronic exertional compartment syndrome...
2017: PloS One
https://www.readbyqxmd.com/read/29057068/case-report-percutaneous-electrical-neural-field-stimulation-in-two-cases-of-sympathetically-mediated-pain
#15
Lynn Fraser, Anna Woodbury
Background: Fibromyalgia and complex regional pain syndrome (CRPS) are both chronic pain syndromes with pathophysiologic mechanisms related to autonomic nervous system dysregulation and central sensitization.  Both syndromes are considered difficult to treat with conventional pain therapies. Case presentations: Here we describe a female veteran with fibromyalgia and a male veteran with CRPS, both of whom failed multiple pharmacologic, physical and psychological therapies for pain, but responded to percutaneous electrical neural field stimulation (PENFS) targeted at the auricular branches of the cranial nerves...
2017: F1000Research
https://www.readbyqxmd.com/read/29037934/the-primary-diagnosis-and-the-coexisting-anxiety-disorders-have-no-impact-on-the-additional-surgical-procedure-after-spinal-cord-stimulators-implantation-an-analysis-of-11-029-patients
#16
Koji Tamai, Zorica Buser, Christopher Wang, Permsak Paholpak, Hiroaki Nakamura, Jeffrey C Wang, Patrick C Hsieh
Studies have demonstrated superior outcomes and cost effectiveness of the spinal cord stimulation (SCS) for the treatment of chronic pain syndromes such as failed back surgery syndrome (FBSS) or complex regional pain syndrome (CRPS). However, little is known about the impact of primary diagnosis or mental disorders on the revision rate. This is the Retrospective cohort study to analyze the reintervention rates based on the primary diagnosis or comorbid mental disorder. Data of the annual trends of SCS use, revision and removal rate of SCS and additional surgical rate after removal was collected and analyzed for patients undergoing SCS between 2007 and 2015, within a private insurance billing database...
October 13, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28990698/psychosocial-co-morbidities-in-interstitial-cystitis-bladder-pain-syndrome-ic-bps-a-systematic-review
#17
REVIEW
Lindsey C McKernan, Colin G Walsh, William S Reynolds, Leslie J Crofford, Roger R Dmochowski, David A Williams
AIMS: Psychosocial factors amplify symptoms of Interstitial Cystitis (IC/BPS). While psychosocial self-management is efficacious in other pain conditions, its impact on an IC/BPS population has rarely been studied. The objective of this review is to learn the prevalence and impact of psychosocial factors on IC/BPS, assess baseline psychosocial characteristics, and offer recommendations for assessment and treatment. METHOD: Following PRISMA guidelines, primary information sources were PubMed including MEDLINE, Embase, CINAHL, and GoogleScholar...
October 9, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28971346/combined-pet-mri-global-warming-summary-report-of-the-6th-international-workshop-on-pet-mri-march-27-29-2017-t%C3%A3-bingen-germany
#18
REVIEW
D L Bailey, B J Pichler, B Gückel, G Antoch, H Barthel, Z M Bhujwalla, S Biskup, S Biswal, M Bitzer, R Boellaard, R F Braren, C Brendle, K Brindle, A Chiti, C la Fougère, R Gillies, V Goh, M Goyen, M Hacker, L Heukamp, G M Knudsen, A M Krackhardt, I Law, J C Morris, K Nikolaou, J Nuyts, A A Ordonez, K Pantel, H H Quick, K Riklund, O Sabri, B Sattler, E G C Troost, M Zaiss, L Zender, Thomas Beyer
The 6th annual meeting to address key issues in positron emission tomography (PET)/magnetic resonance imaging (MRI) was held again in Tübingen, Germany, from March 27 to 29, 2017. Over three days of invited plenary lectures, round table discussions and dialogue board deliberations, participants critically assessed the current state of PET/MRI, both clinically and as a research tool, and attempted to chart future directions. The meeting addressed the use of PET/MRI and workflows in oncology, neurosciences, infection, inflammation and chronic pain syndromes, as well as deeper discussions about how best to characterise the tumour microenvironment, optimise the complementary information available from PET and MRI, and how advanced data mining and bioinformatics, as well as information from liquid biomarkers (circulating tumour cells and nucleic acids) and pathology, can be integrated to give a more complete characterisation of disease phenotype...
October 2, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28953620/different-patterns-in-mental-rotation-of-facial-expressions-in-complex-regional-pain-syndrome-patients
#19
Won Joon Lee, Soo-Hee Choi, Joon Hwan Jang, Jee Youn Moon, Yong Chul Kim, EunChung Noh, Jung Eun Shin, HyunSoon Shin, Do-Hyung Kang
Although facial pain expressions are considered to be the most visible pain behaviors, it is known that the association between pain intensity and facial pain expression is weak for chronic pain. The authors hypothesized that the facial pain expressiveness was altered in chronic pain and investigated it with a mental rotation task using various facial expression, which seems to be associated with actual facial movements. As a task stimulus, 4 types of facial expression stimuli consisted of upper (tightening of eye and furrowed brows) and lower (raising upper lip) pain-specific facial expressions, and upper (eyeball deviation) and lower (tongue protrusion) facial movements not using facial muscles were used...
September 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28944252/anconeus-muscle-pedicle-bone-graft-with-periosteal-coverage-for-osteochondritis-dissecans-of-the-humeral-capitellum
#20
Kozo Shimada, Ko Temporin, Keiichiro Oura, Hiroyuki Tanaka, Ryosuke Noguchi
BACKGROUND: Treatment of advanced osteochondritis dissecans (OCD) of the capitellum is controversial, especially in moderate-sized lesions. PURPOSE: To establish a treatment algorithm for capitellum OCD, we tried to determine the utility of and problems associated with anconeus muscle-pedicle bone graft with periosteal coverage (ABGP) for the treatment of moderate-sized articular OCD defects of the capitellum. STUDY DESIGN: Case series; Level of evidence, 4...
September 2017: Orthopaedic Journal of Sports Medicine
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