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https://www.readbyqxmd.com/read/29691934/temperature-gradient-affects-differentiation-of-gene-expression-and-snp-allele-frequencies-in-the-dominant-lake-baikal-zooplankton-species
#1
Larry L Bowman, Elizaveta S Kondrateva, Maxim A Timofeyev, Lev Y Yampolsky
Local adaptation and phenotypic plasticity are main mechanisms of organisms' resilience in changing environments. Both are affected by gene flow and are expected to be weak in zooplankton populations inhabiting large continuous water bodies and strongly affected by currents. Lake Baikal, the deepest and one of the coldest lakes on Earth, experienced epilimnion temperature increase during the last 100 years, exposing Baikal's zooplankton to novel selective pressures. We obtained a partial transcriptome of Epischura baikalensis (Copepoda: Calanoida), the dominant component of Baikal's zooplankton, and estimated SNP allele frequencies and transcript abundances in samples from regions of Baikal that differ in multy-year average surface temperatures...
April 25, 2018: Molecular Ecology
https://www.readbyqxmd.com/read/29691902/3d-printed-functional-and-biological-materials-on-moving-freeform-surfaces
#2
Zhijie Zhu, Shuang-Zhuang Guo, Tessa Hirdler, Cindy Eide, Xiaoxiao Fan, Jakub Tolar, Michael C McAlpine
Conventional 3D printing technologies typically rely on open-loop, calibrate-then-print operation procedures. An alternative approach is adaptive 3D printing, which is a closed-loop method that combines real-time feedback control and direct ink writing of functional materials in order to fabricate devices on moving freeform surfaces. Here, it is demonstrated that the changes of states in the 3D printing workspace in terms of the geometries and motions of target surfaces can be perceived by an integrated robotic system aided by computer vision...
April 25, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29691894/incremental-value-of-left-atrial-mechanical-dispersion-over-cha-2-ds-2-vasc-score-in-predicting-risk-of-thrombus-formation
#3
Karolina Kupczynska, Blazej W Michalski, Dawid Miskowiec, Jaroslaw D Kasprzak, Ewa Szymczyk, Paulina Wejner Mik, Piotr Lipiec
PURPOSE: To assess the potential ability of two-dimensional speckle tracking analysis (STE) during atrial fibrillation (AF) to identify patients with LA appendage thrombi (LAAT). METHODS: This study involved 93 patients with AF (39% female, 67.1 ± 9.5 years) who were referred for a clinical indication for transesophageal echocardiography (TEE). TEE revealed LAAT in 39 (42%) patients. We analyzed standard parameters of the left ventricle (LV) and LA in transthoracic echocardiography...
April 24, 2018: Echocardiography
https://www.readbyqxmd.com/read/29691844/genetic-and-morphological-evaluation-game-score-for-patients-with-colorectal-liver-metastases
#4
G A Margonis, K Sasaki, S Gholami, Y Kim, N Andreatos, N Rezaee, A Deshwar, S Buettner, P J Allen, T P Kingham, T M Pawlik, J He, J L Cameron, W R Jarnagin, C L Wolfgang, M I D'Angelica, M J Weiss
BACKGROUND: This study sought to develop a clinical risk score for resectable colorectal liver metastasis (CRLM) by combining clinicopathological and clinically available biological indicators, including KRAS. METHODS: A cohort of patients who underwent resection for CRLM at the Johns Hopkins Hospital (JHH) was analysed to identify independent predictors of overall survival (OS) that can be assessed before operation; these factors were combined into the Genetic And Morphological Evaluation (GAME) score...
April 25, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29691839/gene-expression-profiles-for-a-prognostic-immunoscore-in-gastric-cancer
#5
D Zeng, R Zhou, Y Yu, Y Luo, J Zhang, H Sun, J Bin, Y Liao, J Rao, Y Zhang, W Liao
BACKGROUND: Increasing evidence has indicated an association between immune infiltration in gastric cancer and clinical outcome. However, reliable prognostic signatures, based on systematic assessments of the immune landscape inferred from bulk tumour transcriptomes, have not been established. The aim was to develop an immune signature, based on the cellular composition of the immune infiltrate inferred from bulk tumour transcriptomes, to improve the prognostic predictions of gastric cancer...
April 25, 2018: British Journal of Surgery
https://www.readbyqxmd.com/read/29691830/stem-cells-in-osteochondral-tissue-engineering
#6
Eleonora Pintus, Matteo Baldassarri, Luca Perazzo, Simone Natali, Diego Ghinelli, Roberto Buda
Mesenchymal stem cells (MSCs) are pluripotent stem cells with the ability to differentiate into a variety of other connective tissue cells, such as chondral, bony, muscular, and tendon tissue. Bone marrow-derived MSCs are pluripotent cells that can differentiate among others into osteoblasts, adipocytes and chondrocytes.Bone marrow-derived cells may represent the future in osteochondral repair. A one-step arthroscopic technique is developed for cartilage repair, using a device to concentrate bone marrow-derived cells and collagen powder or hyaluronic acid membrane as scaffolds for cell support and platelet gel...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29691826/supercritical-fluid-technology-as-a-tool-to-prepare-gradient-multifunctional-architectures-towards-regeneration-of-osteochondral-injuries
#7
Ana Rita C Duarte, Vitor E Santo, Manuela E Gomes, Rui L Reis
Platelet lysates (PLs) are a natural source of growth factors (GFs) known for its stimulatory role on stem cells which can be obtained after activation of platelets from blood plasma. The possibility to use PLs as growth factor source for tissue healing and regeneration has been pursued following different strategies. Platelet lysates are an enriched pool of growth factors which can be used as either a GFs source or as a three-dimensional (3D) hydrogel. However, most of current PLs-based hydrogels lack stability, exhibiting significant shrinking behavior...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29691815/natural-origin-materials-for-osteochondral-tissue-engineering
#8
Walter Bonani, Weerasak Singhatanadgige, Aramwit Pornanong, Antonella Motta
Materials selection is a critical aspect for the production of scaffolds for osteochondral tissue engineering. Synthetic materials are the result of man-made operations and have been investigated for a variety of tissue engineering applications. Instead, the products of physiological processes and the metabolic activity of living organisms are identified as natural materials. Over the recent decades, a number of natural materials, namely, biopolymers and bioceramics, have been proposed as the main constituent of osteochondral scaffolds, but also as cell carriers and signaling molecules...
2018: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29691809/standardization-of-simple-auxiliary-method-beneficial-to-total-endoscopic-thyroidectomy-on-patients-with-ptc-based-on-retrospective-study-of-356-cases
#9
Shouyi Yan, Wenxin Zhao, Bo Wang, Liyong Zhang
OBJECTIVE: Total endoscopic thyroidectomy (TET) is paid increasing attention to by patients, especially those with thyroid carcinoma. The aim of this study is to evaluate the clinic feasibility of standardization of simple auxiliary method (SOSAM) involved in operating bed adjustment, location of skin traction points and thyroid retractor points for the TET via bilateral breast approach. METHODS: A retrospective study was performed on 356 patients with thyroid carcinoma, who had undergone the TET...
April 24, 2018: Endocrine
https://www.readbyqxmd.com/read/29691799/the-discriminative-power-of-stop-bang-as-a-screening-tool-for-suspected-obstructive-sleep-apnea-in-clinically-referred-patients-considering-gender-differences
#10
Jin Mou, Bethann M Pflugeisen, Brian A Crick, Paul J Amoroso, Kirk T Harmon, Stephen F Tarnoczy, S Shirley Ho, Kimberly A Mebust
PURPOSE: Obstructive sleep apnea (OSA) is the most commonly seen clinical sleep disorder. STOP-Bang, a widely used screening tool, yields a composite score based on eight dichotomized items including male gender. This study was designed to validate STOP-Bang among clinically referred patients and tested alternative scoring designs on tool performance, with a focus on gender differences in OSA. METHOD: STOP-Bang was administered to 403 female and 532 male subjects, followed by comprehensive sleep evaluation that included measurement of apnea-hypopnea indexes...
April 24, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29691790/operation-change-a-new-paradigm-addressing-behavior-change-and-musculoskeletal-health-disparities
#11
Lynne C Jones, Yashika Watkins, Duanny Alva
BACKGROUND: In this study, we examined the implementation and efficacy of Operation Change, a community-based, culturally sensitive program to stimulate behavioral changes in activity level and improve musculoskeletal health in African-American (AA) and Hispanic/Latina (H/L) women with obesity and early-stage osteoarthritis. METHODS: Sixty-two women (32 AA and 30 H/L), 40-75 years old, with nontraumatic knee pain and body mass index values > 30, participated in a 12-week program of presentations, motivational interviewing, goal setting, and physical activities...
April 24, 2018: Journal of Racial and Ethnic Health Disparities
https://www.readbyqxmd.com/read/29691788/tissue-identification-in-a-porcine-model-by-differential-ion-mobility-spectrometry-analysis-of-surgical-smoke
#12
Anton Kontunen, Markus Karjalainen, Jukka Lekkala, Antti Roine, Niku Oksala
Electrosurgery is widely used in various surgical operations. When tissue is cut with high-frequency current, the cell contents at the incision area evaporate and together with water and possible soot particles, form surgical smoke. The smoke contains cell metabolites, and therefore, possible biomarkers for cancer or bacterial infection. Thus, the analysis of surgical smoke could be used in intraoperative medical diagnostics. We present a method that can be used to detect the characteristics of various tissue types by means of differential ion mobility spectrometry (DMS) analysis of surgical smoke...
April 24, 2018: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/29691750/long-term-study-of-cr-ni-zn-and-p-distribution-in-typha-domingensis-growing-in-a-constructed-wetland
#13
Hernán Ricardo Hadad, María de Las Mercedes Mufarrege, Gisela Alfonsina Di Luca, María Alejandra Maine
The aim of this work was to study Cr, Ni, Zn, and P bioaccumulation in different compartments of Typha domingensis plants and sediment in a free-water surface constructed wetland for the treatment of a metallurgical effluent for 5 years. Removal efficiencies were satisfactory. To increase metal tolerance, its transport from belowground to aboveground tissues is reduced, being metal concentrations in the roots and rhizomes significantly higher than in the aerial and submerged parts of leaves. Regarding belowground tissues, metals were retained in the roots, while P was mainly accumulated in rhizomes...
April 25, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29691749/determination-of-size-segregated-elements-in-diesel-biodiesel-blend-exhaust-emissions
#14
Luiz Diego Silva Rocha, Sergio Machado Corrêa
This study was based on the determination of metals in particulate matter emitted by a typical diesel engine used by busses and trucks in Brazil. Emissions were sampled using a cascade impactor, and the engine was operated using diesel with 5% (B5), 10% (B10), 15% (B15), and 20% (B20) of biodiesel. The particulate matter was stratified in different sizes, i.e., 18, 5.6, 3.2, 1.8, 1.0, 0.560, 0.320, 0.180, 0.100, and 0.056 μm. Cd, Co, Cr, Cu, Mn, Mo, Ni, Pb, V, and Zn with concentrations within 10 to 1000 ng m-3 were determined...
April 24, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29691746/fixed-bed-operation-for-manganese-removal-from-water-using-chitosan-bentonite-mno-composite-beads
#15
Anthony M Muliwa, Taile Y Leswifi, Arjun Maity, Aoyi Ochieng, Maurice S Onyango
In the present study, a new composite adsorbent, chitosan/bentonite/manganese oxide (CBMnO) beads, cross-linked with tetraethyl-ortho-silicate (TEOS) was applied in a fixed-bed column for the removal of Mn (II) from water. The adsorbent was characterised by scanning electron microscopy (SEM), Fourier transform infra-red (FT-IR), N2 adsorption-desorption and X-ray photoelectron spectroscopy (XPS) techniques, and moreover the point of zero charge (pHpzc ) was determined. The extend of Mn (II) breakthrough behaviour was investigated by varying bed mass, flow rate and influent concentration, and by using real environmental water samples...
April 24, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29691740/integration-of-a-photocatalytic-multi-tube-reactor-for-indoor-air-purification-in-hvac-systems-a-feasibility-study
#16
Jeroen van Walsem, Jelle Roegiers, Bart Modde, Silvia Lenaerts, Siegfried Denys
This work is focused on an in-depth experimental characterization of multi-tube reactors for indoor air purification integrated in ventilation systems. Glass tubes were selected as an excellent photocatalyst substrate to meet the challenging requirements of the operating conditions in a ventilation system in which high flow rates are typical. Glass tubes show a low-pressure drop which reduces the energy demand of the ventilator, and additionally, they provide a large exposed surface area to allow interaction between indoor air contaminants and the photocatalyst...
April 24, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29691738/a-novel-physiobiological-parameter-based-grading-system-for-resectable-pancreatic-cancer
#17
Takehiro Okabayashi, Yasuo Shima, Tatsuaki Sumiyoshi, Kenta Sui, Jun Iwata, Sojiro Morita, Yasuhiro Shimada, Tatsuo Iiyama
BACKGROUND: Preoperative methods to estimate disease-specific survival (DSS) for resectable pancreatic cancer are limited. OBJECTIVE: The aim of this study was to develop and validate a pretreatment physiobiological prognostic model in patients with radiologically resectable pancreatic cancer. METHODS: A retrospective review of a prospectively maintained institutional database was undertaken to identify patients who underwent potentially curative resection for radiologically resectable pancreatic cancer...
April 24, 2018: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/29691663/tooth-sectioning-for-coronectomy-how-to-perform
#18
József Szalma, László Vajta, Lajos Olasz, Edina Lempel
OBJECTIVES: The aim of this study was to determine the increase in heat production, preparation time, and cutting surface quality of conventional, high-speed rotating instruments and piezoelectric preparation for coronectomy procedures. MATERIALS AND METHODS: One hundred intact extracted molars were sectioned horizontally, sub-totally, 1 mm under the cemento-enamel line with five methods: (1) tungsten carbide torpedo (TcT), (2) round (TcR) drills using a conventional speed surgical straight handpiece (< 40,000 min-1 ), (3) tungsten carbide fissure (TcF), (4) diamond torpedo (DT) drills using a surgical high-speed, contra-angle handpiece (~ 120,000 min-1 ), or (5) a saw-like piezoelectric tip (PT)...
April 24, 2018: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29691659/colon-cancer-with-perforation
#19
REVIEW
Kensuke Otani, Kazushige Kawai, Keisuke Hata, Toshiaki Tanaka, Takeshi Nishikawa, Kazuhito Sasaki, Manabu Kaneko, Koji Murono, Shigenobu Emoto, Hiroaki Nozawa
Perforation of the colon is a rare complication for patients with colon cancer and usually requires emergent surgery. The characteristics of perforation differ based on the site of perforation, presenting as either perforation at the cancer site or perforation proximal to the cancer site. Peritonitis due to perforation tends to be more severe in cases of perforation proximal to the cancer site; however, the difference in the outcome between the two types remains unclear. Surgical treatment of colon cancer with perforation has changed over time...
April 24, 2018: Surgery Today
https://www.readbyqxmd.com/read/29691633/emdunifrac-exact-linear-time-computation-of-the-unifrac-metric-and-identification-of-differentially-abundant-organisms
#20
Jason McClelland, David Koslicki
Both the weighted and unweighted UniFrac distances have been very successfully employed to assess if two communities differ, but do not give any information about how two communities differ. We take advantage of recent observations that the UniFrac metric is equivalent to the so-called earth mover's distance (also known as the Kantorovich-Rubinstein metric) to develop an algorithm that not only computes the UniFrac distance in linear time and space, but also simultaneously finds which operational taxonomic units are responsible for the observed differences between samples...
April 25, 2018: Journal of Mathematical Biology
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