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Prospective health assessment

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https://www.readbyqxmd.com/read/29165934/first-rapid-assessment-of-avoidable-blindness-survey-in-the-maldives-prevalence-and-causes-of-blindness-and-cataract-surgery
#1
Ubeydulla Thoufeeq, Taraprasad Das, Hans Limburg, Maharshi Maitra, Lapam Panda, Asim Sil, John Trevelyan, Yuddha Sapkota
PURPOSE: A nationwide rapid assessment of avoidable blindness survey was undertaken in the Maldives among people aged 50 years or more to assess the prevalence and causes of blindness and visual impairment, cataract surgical coverage, cataract surgery outcome, and barriers to uptake of cataract surgical services. DESIGN: Prospective population-based study. METHODS: In the cluster sampling probability proportionate to size method, 3100 participants in 62 clusters across all 20 atolls were enrolled through house-to-house visits...
November 22, 2017: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/29165614/long-term-health-in-recipients-of-transplanted-in-vitro-propagated-spermatogonial-stem-cells
#2
Callista L Mulder, Lisa A E Catsburg, Yi Zheng, Cindy M de Winter-Korver, Saskia K M van Daalen, Madelon van Wely, Steven Pals, Sjoerd Repping, Ans M M van Pelt
STUDY QUESTION: Is testicular transplantation of in vitro propagated spermatogonial stem cells associated with increased cancer incidence and decreased survival rates in recipient mice? SUMMARY ANSWER: Cancer incidence was not increased and long-term survival rate was not altered after transplantation of in vitro propagated murine spermatogonial stem cells (SSCs) in busulfan-treated recipients as compared to non-transplanted busulfan-treated controls. WHAT IS KNOWN ALREADY: Spermatogonial stem cell autotransplantation (SSCT) is a promising experimental reproductive technique currently under development to restore fertility in male childhood cancer survivors...
November 18, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29165579/investigating-mediators-of-the-poor-pneumonia-outcomes-of-human-immunodeficiency-virus-exposed-but-uninfected-children
#3
Matthew S Kelly, Jiayin Zheng, Sefelani Boiditswe, Andrew P Steenhoff, Kristen A Feemster, Tonya Arscott-Mills, Boitshepe Seme, Bakgaki Ratshaa, Ikanyeng Rulaganyang, Mohamed Z Patel, Savarra Mantzor, Samir S Shah, Coleen K Cunningham
Background: Human immunodeficiency virus-exposed but uninfected (HIV-EU) children have a higher mortality rate than the children of HIV-negative mothers (HIV-unexposed). Causal mediators of the poor health outcomes of HIV-EU children remain poorly defined. Methods: We conducted a hospital-based prospective cohort study of children aged 1 to 23 months with clinically defined pneumonia. The children were recruited at a referral hospital in Gaborone, Botswana, between April 2012 and June 2016...
November 20, 2017: Journal of the Pediatric Infectious Diseases Society
https://www.readbyqxmd.com/read/29165559/impact-of-pre-admission-oral-anticoagulation-on-ischaemic-stroke-volume-lesion-pattern-and-frequency-of-intracranial-arterial-occlusion-in-patients-with-atrial-fibrillation
#4
Joanna Dietzel, Sophie K Piper, Rudi Ruschmann, Christian Wollboldt, Tatiana Usnich, Simon Hellwig, Ivana Galinovic, Heinrich J Audebert, Matthias Endres, Kersten Villringer, Jochen B Fiebach, Karl Georg Haeusler
Aims: Therapeutic oral anticoagulation on hospital admission reduces morbidity and mortality after acute ischaemic stroke in patients with atrial fibrillation (AF). The underlying mechanism is not fully understood. In order to assess the impact of INR-level on admission on stroke volume, lesion pattern and the frequency of intracranial arterial occlusion, we analysed serial MRI measurements in AF patients suffering acute ischaemic stroke. Methods: and results This subgroup analysis of the prospective '1000Plus' study included patients with acute ischaemic stroke and known AF or a first episode of AF in hospital...
November 20, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29165541/frailty-exists-in-younger-adults-admitted-as-surgical-emergency-leading-to-adverse-outcomes
#5
R Smart, B Carter, J McGovern, S Luckman, A Connelly, J Hewitt, T Quasim, S Moug
BACKGROUND: Frailty is prevalent in the older adult population (≥65 years of age) and results in adverse outcomes in the emergency general surgical population. OBJECTIVE: To determine whether frailty exists in the younger adult emergency surgical population (<65 years) and what influence frailty may have on patient related outcomes. DESIGN: Prospective observational cohort study. SETTING: Emergency general surgical admissions...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/29165412/-stabilizing-effectiveness-of-orthokeratology-and-long-term-minute-concentration-atropine-therapy-in-myopia-draft-report
#6
T Yu Verzhanskaya, E P Tarutta
The rational for the study was the high prevalence of myopia in the world. According to the World Health Organization (WHO), myopia is one of the five leading causes of blindness and low vision. Of recent reports on conservative measures for the stabilization of myopia, two areas of investigation deserve attention: methods of optical correction that affect peripheral refraction, orthokeratology lenses (OKL) in particular, and pharmacotherapy. The aim of the study was to evaluate the effectiveness and safety of myopia control in pediatric patients by combining two methods - OKL wearing and instillation of extra low doses of atropine (0...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/29164802/use-of-bacillus-thuringiensis-israelensis-in-integrated-vector-control-of-aedes-sp-in-sri-lanka-a-prospective-controlled-effectiveness-study
#7
H A Tissera, P C Samaraweera, B D W Jayamanne, M D S Janaki, M P P U Chulasiri, C Rodrigo, S D Fernando
OBJECTIVES: The annual incidence of dengue has been increasing over the last few years in Sri Lanka with seasonal epidemics. Biological control of the vector has not been part of the integrated vector control implemented by the public health authorities of Sri Lanka so far. This pilot study assessed the effectiveness of using Bacillus thuringiensis israelensis (Bti) spray to control the Aedes mosquito vector population density. METHODS: Prospective controlled effectiveness study in 3 administrative divisions of Colombo...
November 22, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29164603/18f-pet-with-florbetapir-for-the-early-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-in-people-with-mild-cognitive-impairment-mci
#8
REVIEW
Gabriel Martínez, Robin Wm Vernooij, Paulina Fuentes Padilla, Javier Zamora, Xavier Bonfill Cosp, Leon Flicker
BACKGROUND: (18)F-florbetapir uptake by brain tissue measured by positron emission tomography (PET) is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in an established dementia diagnosis. However, the National Institute on Aging and Alzheimer's Association (NIA-AA) revised the diagnostic criteria for Alzheimer's disease and confidence in the diagnosis of mild cognitive impairment (MCI) due to Alzheimer's disease may be increased when using amyloid biomarkers tests like (18)F-florbetapir...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29164602/18f-pet-with-flutemetamol-for-the-early-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-in-people-with-mild-cognitive-impairment-mci
#9
REVIEW
Gabriel Martínez, Robin Wm Vernooij, Paulina Fuentes Padilla, Javier Zamora, Leon Flicker, Xavier Bonfill Cosp
BACKGROUND: (18)F-flutemetamol uptake by brain tissue, measured by positron emission tomography (PET), is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in an established dementia diagnosis. However, the National Institute on Aging and Alzheimer's Association (NIA-AA) revised the diagnostic criteria for Alzheimer's disease and the confidence in the diagnosis of mild cognitive impairment (MCI) due to Alzheimer's disease may be increased when using some amyloid biomarkers tests like (18)F-flutemetamol...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29164600/18f-pet-with-florbetaben-for-the-early-diagnosis-of-alzheimer-s-disease-dementia-and-other-dementias-in-people-with-mild-cognitive-impairment-mci
#10
REVIEW
Gabriel Martínez, Robin Wm Vernooij, Paulina Fuentes Padilla, Javier Zamora, Leon Flicker, Xavier Bonfill Cosp
BACKGROUND: (18)F-florbetaben uptake by brain tissue, measured by positron emission tomography (PET), is accepted by regulatory agencies like the Food and Drug Administration (FDA) and the European Medicine Agencies (EMA) for assessing amyloid load in people with dementia. Its added value is mainly demonstrated by excluding Alzheimer's pathology in an established dementia diagnosis. However, the National Institute on Aging and Alzheimer's Association (NIA-AA) revised the diagnostic criteria for Alzheimer's disease and confidence in the diagnosis of mild cognitive impairment (MCI) due to Alzheimer's disease may be increased when using some amyloid biomarkers tests like (18)F-florbetaben...
November 22, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29164595/frequency-of-leaving-the-house-and-mortality-from-age-70-to-95
#11
Jeremy M Jacobs, Aliza Hammerman-Rozenberg, Jochanan Stessman
OBJECTIVES: To determine the association between frequency of leaving the house and mortality. DESIGN: Prospective follow-up of an age-homogenous, representative, community-dwelling birth cohort (born 1920-21) from the Jerusalem Longitudinal Study (1990-2015). SETTING: Home. PARTICIPANTS: Individuals aged 70 (n = 593), 78 (n = 973), 85 (n = 1164), and 90 (n = 645), examined in 1990, 1998, 2005, and 2010, respectively...
November 22, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29164493/mapping-quality-of-life-eq-5d-from-dapsa-clinical-dapsa-and-haq-in-psoriatic-arthritis
#12
Tomas Mlcoch, Jan Tuzil, Liliana Sedova, Jiri Stolfa, Monika Urbanova, David Suchy, Andrea Smrzova, Jitka Jircikova, Tereza Hrnciarova, Karel Pavelka, Tomas Dolezal
BACKGROUND: Clinical trials and observational studies lacking measures of health-related quality of life (QoL) are often inapplicable when conducting cost-effectiveness analyses using quality-adjusted life-years (QALYs). The only solution is to map QoL ex post from additionally collected clinical outcomes and generic QoL instruments. Nonetheless, mapping studies are absent in psoriatic arthritis (PsA). METHODS: In this 2-year, prospective, multicentre, non-interventional study of PsA patients, EQ-5D and key clinical parameters such as Disease Activity in PsA (DAPsA), clinical DAPsA (cDAPsA; DAPsA without C-reactive protein [CRP]), and Health Assessment Questionnaire disability index (HAQ) were collected...
November 21, 2017: Patient
https://www.readbyqxmd.com/read/29163937/development-and-validation-of-a-simplified-algorithm-for-neonatal-gestational-age-assessment-protocol-for-the-alliance-for-maternal-newborn-health-improvement-amanhi-prospective-cohort-study
#13
Abdullah Baqui, Parvez Ahmed, Sushil Kanta Dasgupta, Nazma Begum, Mahmoodur Rahman, Nasreen Islam, Mohammad Quaiyum, Betty Kirkwood, Karen Edmond, Caitlin Shannon, Samuel Newton, Lisa Hurt, Fyezah Jehan, Imran Nisar, Atiya Hussain, Naila Nadeem, Muhammad Ilyas, Anita Zaidi, Sunil Sazawal, Saikat Deb, Arup Dutta, Usha Dhingra, Said Moh'd Ali, Davidson H Hamer, Katherine Ea Semrau, Marina Straszak-Suri, Caroline Grogan, Godfrey Bemba, Anne Cc Lee, Blair J Wylie, Alexander Manu, Sachiyo Yoshida, Rajiv Bahl
Objective: The objective of the Alliance for Maternal and Newborn Health Improvement (AMANHI) gestational age study is to develop and validate a programmatically feasible and simple approach to accurately assess gestational age of babies after they are born. The study will provide accurate, population-based rates of preterm birth in different settings and quantify the risks of neonatal mortality and morbidity by gestational age and birth weight in five South Asian and sub-Saharan African sites...
December 2017: Journal of Global Health
https://www.readbyqxmd.com/read/29162573/data-quality-and-30-day-survival-for-out-of-hospital-cardiac-arrest-in-the-uk-out-of-hospital-cardiac-arrest-registry-a-data-linkage-study
#14
Sangeerthana Rajagopal, Scott J Booth, Terry P Brown, Chen Ji, Claire Hawkes, A Niroshan Siriwardena, Kim Kirby, Sarah Black, Robert Spaight, Imogen Gunson, Samantha J Brace-McDonnell, Gavin D Perkins
OBJECTIVES: The Out-of-Hospital Cardiac Arrest Outcomes (OHCAO) project aims to understand the epidemiology and outcomes of out-of-hospital cardiac arrest (OHCA) across the UK. This data linkage study is a subproject of OHCAO. The aim was to establish the feasibility of linking OHCAO data to National Health Service (NHS) patient demographic data and Office for National Statistics (ONS) date of death data held on the NHS Personal Demographics Service (PDS) database to improve OHCAO demographic data quality and enable analysis of 30-day survival from OHCA...
November 20, 2017: BMJ Open
https://www.readbyqxmd.com/read/29162196/when-inflammation-and-depression-go-together-the-longitudinal-effects-of-parent-child-relationships
#15
Steven R H Beach, Man Kit Lei, Ronald L Simons, Ashley B Barr, Leslie G Simons, Katherine Ehrlich, Gene H Brody, Robert A Philibert
Parent-child relationships have long-term effects on health, particularly later inflammation and depression. We hypothesized that these effects would be mediated by later romantic partner relationships and elevated stressors in young adulthood, helping promote chronic, low grade, inflammation as well as depressive symptoms, and driving their covariation. It has been proposed recently that youth experiencing harsher parenting may also develop a stronger association between inflammation and depressive symptoms in adulthood and altered effects of stressors on outcomes...
December 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29162194/childhood-abuse-and-neglect-and-physical-health-at-midlife-prospective-longitudinal-evidence
#16
William F Johnson, Chloe O Huelsnitz, Elizabeth A Carlson, Glenn I Roisman, Michelle M Englund, Gregory E Miller, Jeffry A Simpson
Previous research suggests that the experience of abuse and neglect in childhood has negative implications for physical health in adulthood. Using data from the Minnesota Longitudinal Study of Risk and Adaptation (N = 115), the present research examined the predictive significance of childhood physical abuse, sexual abuse, and physical/cognitive neglect for multilevel assessments of physical health at midlife (age 37-39 years), including biomarkers of cardiometabolic risk, self-reports of quality of health, and a number of health problems...
December 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29162171/positive-maternal-mental-health-during-pregnancy-associated-with-specific-forms-of-adaptive-development-in-early-childhood-evidence-from-a-longitudinal-study
#17
Desiree Y Phua, Michelle K Z L Kee, Dawn X P Koh, Anne Rifkin-Graboi, Mary Daniels, Helen Chen, Yap Seng Chong, Birit F P Broekman, Iliana Magiati, Neerja Karnani, Michael Pluess, Michael J Meaney
The quality of prenatal maternal mental health, from psychological stress and depressive symptoms to anxiety and other nonpsychotic mental disorders, profoundly affects fetal neurodevelopment. Despite the evidence for the influence of positive mental well-being on health, there is, to our knowledge, no research examining the possible effects of positive antenatal mental health on the development of the offspring. Using exploratory bifactor analysis, this prospective study (n = 1,066) demonstrated the feasibility of using common psychiatric screening tools to examine the effect of positive maternal mental health...
December 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/29161902/organizational-level-recruitment-of-barbershops-as-health-promotion-intervention-study-sites-addressing-health-disparities-among-black-men
#18
Sula Hood, Marla Hall, Carrissa Dixon, David Jolly, Laura Linnan
This article describes the process and results associated with the organizational-level recruitment of Black barbershops into Fitness in the Shop (FITShop), a 6-month barbershop-based intervention study designed to promote physical activity among Black men. Organizational-level recruitment activities included (1) a telephone call to prospective barbershop owners to assess their interest and eligibility for participation, (2) an organizational eligibility letter sent to all interested and eligible barbershops, (3) a visit to interested and eligible barbershops, where a culturally sensitive informational video was shown to barbershop owners to describe the study activities and share testimonies from trusted community stakeholders, and (4) a signed agreement with barbershop owners and barbers, which formalized the organizational partnership...
March 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/29161890/impact-of-physical-activity-on-the-risk-of-cardiovascular-disease-in-middle-aged-and-older-adults-epic-norfolk-prospective-population-study
#19
Sangeeta Lachman, S Matthijs Boekholdt, Robert N Luben, Stephen J Sharp, Soren Brage, Kay-Tee Khaw, Ron Jg Peters, Nicholas J Wareham
Background There is broad consensus that regular physical activity yields major health benefits. However, current guidelines on physical activity are mainly aimed at middle-aged adults. It is unclear whether physical activity also translates into cardiovascular health benefits in older adults. Therefore, we aimed to compare the association between different levels of physical activity and the risk of cardiovascular disease (CVD) in elderly to middle-aged individuals. Methods We analysed data from the EPIC Norfolk prospective population study...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29161402/fit-for-surgery-perspectives-on-preoperative-exercise-testing-and-training
#20
K Richardson, D Z H Levett, S Jack, M P W Grocott
There is a consistent relationship between physical activity, physical fitness, and health across almost all clinical contexts, including the perioperative setting. Physiological measurements obtained during physical exercise may be used to infer the risk of adverse outcome after major surgery. In particular, data obtained from perioperative cardiopulmonary exercise testing have an expanding role in perioperative care. Such information may be used to inform a variety of changes in clinical practice, including interventions that may reduce the risk of perioperative adverse events...
December 1, 2017: British Journal of Anaesthesia
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