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https://www.readbyqxmd.com/read/29786588/-infectious-complications-of-prostate-biopsy
#1
Marcin Łykowski, Bartosz Dybowski, Sławomir Poletajew, Tomasz Piecha, Piotr Radziszewski
Prostate cancer is the second most common malignancy in men in Poland. Prostate biopsy remains the gold standard for diagnosis. Every year, the number of procedures is increasing, so knowledge of possible complications is becoming crucial. Over time, a continuous increase in infectious complications of prostate biopsy is observed, so it is important to identify risk factors and preventive methods. Antibiotic prophylaxis is mandatory for prostate biopsy. Simultaneously, complications after prostate biopsy affect as many as 90% of patients, including up to 17% of infective complications...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29786087/a-comparison-of-23-gauge-and-20-gauge-vitrectomy-for-proliferative-sickle-cell-retinopathy-clinical-outcomes-and-surgical-management
#2
Jason Ho, Anna Grabowska, Marta Ugarte, Mahiul Mk Muqit
AIMS: To report anatomical and functional outcomes in patients with proliferative sickle retinopathy (PSR) who underwent 23-gauge (23G) and 20-gauge (20G) vitrectomy. METHODS: Retrospective consecutive case series of patients who underwent vitreoretinal intervention for complications of PSR between April 2009 and February 2015. Operations were performed at a tertiary referral centre, Moorfields Eye Hospital. Visual acuity and anatomical success rates were evaluated for PSR complicated by retinal detachment, tractional vitreous haemorrhage and macular hole...
May 22, 2018: Eye
https://www.readbyqxmd.com/read/29786004/anterior-segment-optical-coherence-tomography-of-intraocular-lens-opacification
#3
Saurabh Choudhry, Neha Goel, Aanchal Mehta, Nidhi Mahajan
Postoperative opacification of a hydrophilic acrylic intraocular lens (IOL) is an uncommon complication. A 57-year-old diabetic female who had undergone phacoemulsification with IOL implantation in her right eye 16 years back presented with diminution of vision in the same eye for 3 years. Significant IOL opacification was observed clinically and anterior segment optical coherence tomography clearly delineated the intraoptic deposits, sparing the haptics, and edges of the optic. IOL explant and exchange was performed leading to restoration of visual acuity to 6/9...
June 2018: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29785665/why-weight-an-analytic-review-of-obesity-management-diabetes-prevention-and-cardiovascular-risk-reduction
#4
REVIEW
L I Igel, K H Saunders, J J Fins
PURPOSE OF REVIEW: In this review, we examine one of the ironies of American health care-that we pay more for disease management than disease prevention. Instead of preventing type 2 diabetes (T2DM) by treating its precursor, obesity, we fail to provide sufficient insurance coverage for weight management only to fund the more costly burden of overt T2DM. RECENT FINDINGS: There is a vital need for expanded insurance coverage to help foster a weight-centric approach to T2DM management...
May 21, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29785346/integrated-bioinformatic-changes-and-analysis-of-retina-with-time-in-diabetic-rats
#5
Zekai Cui, Qiaolang Zeng, Yonglong Guo, Shiwei Liu, Jiansu Chen
Diabetic retinopathy (DR) is the most common chronic complication of diabetes. It can cause impaired vision and even blindness. However, the pathological mechanism of DR is still unknown. In the present study, we use bioinformatic analysis to reveal the pathological changes of early DR in a streptozotocin (STZ) induced diabetes rat model. The dataset GSE28831 was downloaded from the Gene Expression Omnibus (GEO) database. To clarify the pathological mechanism of early DR, genes which were up-regulated (UP group) or down-regulated (DOWN group) over time were identified...
2018: PeerJ
https://www.readbyqxmd.com/read/29785272/abdominal-obesity-in-type-1-diabetes-associated-with-gender-cardiovascular-risk-factors-and-complications-and-difficulties-achieving-treatment-targets-a-cross-sectional-study-at-a-secondary-care-diabetes-clinic
#6
Eva O Melin, Hans O Thulesius, Magnus Hillman, Mona Landin-Olsson, Maria Thunander
Background: Abdominal obesity is linked to cardiovascular diseases in type 1 diabetes (T1D). The primary aim was to explore associations between abdominal obesity and cardiovascular complications, metabolic and inflammatory factors. The secondary aim was to explore whether achieved recommended treatment targets differed between the obese and non-obese participants. Methods: Cross sectional study of 284 T1D patients (age 18-59 years, men 56%), consecutively recruited from one secondary care specialist diabetes clinic in Sweden...
2018: BMC Obesity
https://www.readbyqxmd.com/read/29784563/limited-benefit-of-haemoglobin-glycation-index-as-risk-factor-for-cardiovascular-disease-in-type-2-diabetes-patients
#7
H B Østergaard, T Mandrup-Poulsen, G F N Berkelmans, Y van der Graaf, F L J Visseren, J Westerink
BACKGROUND: The haemoglobin glycation index (HGI) has been proposed as a marker of interindividual differences in haemoglobin glycosylation. Previous studies have shown a relationship between high HGI and risk of cardiovascular disease (CVD) in patients with diabetes. However, no studies have investigated the role of previous CVD in this association. METHODS: The study cohort comprised patients with type 2 diabetes mellitus (T2DM; n=1910) included in the Second Manifestations of Arterial Disease (SMART) study...
May 8, 2018: Diabetes & Metabolism
https://www.readbyqxmd.com/read/29784146/trends-in-cause-specific-mortality-among-adults-with-and-without-diagnosed-diabetes-in-the-usa-an-epidemiological-analysis-of-linked-national-survey-and-vital-statistics-data
#8
Edward W Gregg, Yiling J Cheng, Meera Srinivasan, Ji Lin, Linda S Geiss, Ann L Albright, Giuseppina Imperatore
BACKGROUND: Large reductions in diabetes complications have altered diabetes-related morbidity in the USA. It is unclear whether similar trends have occurred in causes of death. METHODS: Using data from the National Health Interview Survey Linked Mortality files from 1985 to 2015, we estimated age-specific death rates and proportional mortality from all causes, vascular causes, cancers, and non-vascular, non-cancer causes among US adults by diabetes status. FINDINGS: From 1988-94, to 2010-15, all-cause death rates declined by 20% every 10 years among US adults with diabetes (from 23·1 [95% CI 20·1-26·0] to 15·2 [14·6-15·8] per 1000 person-years), while death from vascular causes decreased 32% every 10 years (from 11·0 [9·2-12·2] to 5·2 [4·8-5·6] per 1000 person-years), deaths from cancers decreased 16% every 10 years (from 4·4 [3·2-5·5] to 3·0 [2·8-3·3] per 1000 person-years), and the rate of non-vascular, non-cancer deaths declined by 8% every 10 years (from 7·7 [6·3-9·2] to 7·1 [6·6-7·5])...
May 18, 2018: Lancet
https://www.readbyqxmd.com/read/29784059/diabetes-intervention-accentuating-diet-and-enhancing-metabolism-diadem-i-a-randomised-controlled-trial-to-examine-the-impact-of-an-intensive-lifestyle-intervention-consisting-of-a-low-energy-diet-and-physical-activity-on-body-weight-and-metabolism-in-early
#9
Shahrad Taheri, Odette Chagoury, Hadeel Zaghloul, Sara Elhadad, Salma Hayder Ahmed, Omar Omar, Sherryl Payra, Salma Ahmed, Neda El Khatib, Rasha Abou Amona, Katie El Nahas, Matthew Bolton, Henem Chaar, Noor Suleiman, Amin Jayyousi, Mahmoud Zirie, Ibrahim Janahi, Wahiba Elhag, Abdulla Alnaama, Abduljaleel Zainel, Dahlia Hassan, Tim Cable, Mary Charlson, Martin Wells, Abdulla Al-Hamaq, Samya Al-Abdulla, Abdul Badi Abou-Samra
BACKGROUND: Type 2 diabetes mellitus (T2DM) and obesity are syndemic and will have a significant impact on affected individuals and healthcare services worldwide. Evidence shows that T2DM remission can be achieved with significant weight loss in those who are younger with early diabetes and requiring fewer medications for glycaemic control. DIADEM-I aims to examine the impact of an intensive lifestyle intervention (ILI) using a low-energy diet (LED) meal replacement approach combined with physical activity in younger individuals with early T2DM...
May 21, 2018: Trials
https://www.readbyqxmd.com/read/29784023/delayed-presentation-of-severe-rhabdomyolysis-leading-to-acute-kidney-injury-following-atorvastatin-gemfibrozil-combination-therapy-a-case-report
#10
Chamara Dalugama, Manoji Pathirage, S A M Kularatne
BACKGROUND: Rhabdomyolysis is a rare but serious complication of lipid-lowering therapy. Statin and fibrate combination increases the risk of rhabdomyolysis possibly by pharmacodynamic interactions. Advanced age, diabetes, hypothyroidism, polypharmacy, and renal impairment are known to increase the risk of rhabdomyolysis. Management strategies include fluid resuscitation and urine alkalinization. Renal indications such as refractory hyperkalemia, acidosis, fluid overload, or uremic complications mandate renal replacement therapy in rhabdomyolysis...
May 22, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29784020/atrioventricular-block-after-acute-myocardial-infarction-and-its-association-with-other-clinical-parameters-in-pakistani-patients-an-institutional-perspective
#11
Kashif Ali Hashmi, Amir Shehzad, Atif Ali Hashmi, Amir Khan
OBJECTIVES: Conduction defects complicating acute myocardial infarction are frequently associated with increased morbidity and mortality. As frequency of this complication has not been widely studied in our population, therefore in this study we aimed to evaluate the frequency of complete atrioventricular block in patients with acute ST segment elevation myocardial infarction and its association with other clinical parameters. RESULTS: The mean age of the patients was 50...
May 21, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29783933/enablers-and-barriers-to-physical-activity-in-overweight-and-obese-pregnant-women-an-analysis-informed-by-the-theoretical-domains-framework-and-com-b-model
#12
C Flannery, S McHugh, A E Anaba, E Clifford, M O'Riordan, L C Kenny, F M McAuliffe, P M Kearney, M Byrne
BACKGROUND: Obesity during pregnancy is associated with increased risk of gestational diabetes mellitus (GDM) and other complications. Physical activity is a modifiable lifestyle factor that may help to prevent these complications but many women reduce their physical activity levels during pregnancy. Interventions targeting physical activity in pregnancy are on-going but few identify the underlying behaviour change mechanisms by which the intervention is expected to work. To enhance intervention effectiveness, recent tools in behavioural science such as the Theoretical Domains Framework (TDF) and COM-B model (capability, opportunity, motivation and behaviour) have been employed to understand behaviours for intervention development...
May 21, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29783897/continuous-glucose-monitoring-current-use-in-diabetes-management-and-possible-future-applications
#13
Martina Vettoretti, Giacomo Cappon, Giada Acciaroli, Andrea Facchinetti, Giovanni Sparacino
The recent announcement of the production of new low-cost continuous glucose monitoring (CGM) sensors, the approval of marketed CGM sensors for making treatment decisions, and new reimbursement criteria have the potential to revolutionize CGM use. After briefly summarizing current CGM applications, we discuss how, in our opinion, these changes are expected to extend CGM utilization beyond diabetes patients, for example, to subjects with prediabetes or even healthy individuals. We also elaborate on how the integration of CGM data with other relevant information, for example, health records and other medical device/wearable sensor data, will contribute to creating a digital data ecosystem that will improve our understanding of the etiology and complications of diabetes and will facilitate the development of data analytics for personalized diabetes management and prevention...
May 1, 2018: Journal of Diabetes Science and Technology
https://www.readbyqxmd.com/read/29783717/associations-of-maternal-vitamin-d-deficiency-with-pregnancy-and-neonatal-complications-in-developing-countries-a-systematic-review
#14
REVIEW
Paige van der Pligt, Jane Willcox, Ewa A Szymlek-Gay, Emily Murray, Anthony Worsley, Robin M Daly
Pregnant women in Asia, the Middle East, Africa and Latin America are at risk of vitamin D deficiency (VDD) and prevalence throughout these regions are among the highest, globally. Maternal VDD has been associated with increased risk of a number of adverse maternal and neonatal health outcomes, yet research from developing countries is limited. We assessed the associations of maternal VDD during pregnancy with adverse health outcomes by synthesizing the literature from observational studies conducted in developing countries...
May 18, 2018: Nutrients
https://www.readbyqxmd.com/read/29783249/prognosis-of-ischaemic-heart-disease-in-patients-with-newly-diagnosed-dm-type-2-by-logistic-regression
#15
Alina Urbanovych, Halyna Suslyk
OBJECTIVE: Introduction: Diabetes Mellitus (DM) type 2 is an important medical and social problem all around the world. One of the most serious and widespread complications of DM type 2 is a damage to the cardiovascular system. The aim was to study the way of how to predict the IHD development in patients with the newly diagnosed DM type 2 by building a mathematical model with the help of statistical method, in particular, a logistic regression, which allows predicting the occurrence of IHD by the levels of proven biochemical and anthropometric indices...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29783031/a-unique-all-payer-rate-setting-system-controls-the-cost-but-not-the-racial-disparity-in-lower-extremity-revascularization-procedures
#16
Besma Nejim, Robert J Beaulieu, Husain Alshaikh, Mohammed Hamouda, Joseph Canner, Mahmoud B Malas
BACKGROUND: Patients with peripheral arterial disease (PAD) often have high comorbidity burden that may complicate post-interventional course and drive increased healthcare expenditures. Racial disparity had been observed in lower extremity revascularization (LER) patterns and outcomes. In 2014, Maryland adopted an all-payer rate setting system to limit the rising hospitalization costs. This resulted in an aggregate payment system in which hospital compensation takes place as an overall per capita expenditure for hospital services...
May 18, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29782986/antiglycation-study-of-hmg-r-inhibitors-and-tocotrienol-against-glycated-bsa-and-ldl-a-comparative-study
#17
Rabia Nabi, Sahir Sultan Alvi, Rizwan Khan, Shafeeque Ahmad, Saheem Ahmad, M Salman Khan
Non-enzymatic glycation mediated advanced glycation end products (AGEs) generation results in the pathogenesis of diabetic complications and atherosclerotic cardiovascular disease (ASCVD) which is greatly influenced by 3-hydroxy-3-methyl-glutaryl Co-A reductase (HMG-R) activity. HMG-R inhibitors, statins, are well known for reducing mortality and morbidity of ASCVD in patients with diabetes due to their pleiotropic effects independent of cholesterol lowering. Due to distinct chemical structures, various statins may play important role in the inhibition of AGEs mediated pathologies...
May 18, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29782936/stratification-of-type-2-diabetes-based-on-routine-clinical-markers
#18
Narges Safai, Ashfaq Ali, Peter Rossing, Martin Ridderstråle
AIMS: We hypothesized that patients with dysregulated type 2 diabetes may be stratified based on routine clinical markers. METHODS: In this retrospective cohort study, diabetes related clinical measures including age at onset, diabetes duration, HbA1c , BMI, HOMA2-β, HOMA2-IR and GAD65 autoantibodies, were used for sub-grouping patients by K-means clustering and for adjusting. Probability of diabetes complications (95% confidence interval), were calculated using logistic regression...
May 18, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29782863/analysis-of-mulberry-leaf-components-in-the-treatment-of-diabetes-using-network-pharmacology
#19
Qi Ge, Liang Chen, Min Tang, Shu Zhang, Lu Gao, Shangshang Ma, Lanlan Liu, Ming Kong, Qin Yao, Keping Chen, Fan Feng
Mulberry leaves are one of the most commonly used medicinal and herbaceous traditional Chinese medicines that are currently considered for the treatment of diabetes mellitus and its complications. The alkaloids, flavonoids, and polysaccharides in mulberry leaves impart regulatory effects on blood sugar levels. To identify the hypoglycemia-related active components in mulberry leaves and their targets, the present study conducted gas chromatography-mass spectrometer (GC/MS), which identified 202 components of mulberry leaf, of which 22 components may have significant curative effects on diabetes mellitus and its complications and chronic inflammation...
May 18, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29782669/prevalence-of-active-charcot-disease-in-the-east-midlands-of-england
#20
L Metcalf, M Musgrove, J Bentley, R Berrington, D Bunting, M Mousley, J Thompson, M Sprengel, V Turtle-Savage, F Game, W Jeffcoate
AIMS: To undertake a prospective point prevalence study of the prevalence of active Charcot neuro-inflammatory osteoarthropathy (Charcot disease) in a circumscribed part of England and to audit the time elapsing between disease onset and first diagnosis. METHODS: The prevalence of active Charcot disease of the foot during a single month was assessed by specialist foot care teams at seven secondary care services in the East Midlands region of England. RESULTS: A total of 90 cases were identified, representing 4...
May 21, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
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