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https://www.readbyqxmd.com/read/28073472/the-interaction-between-cyanobacteria-and-zooplankton-in-a-more-eutrophic-world
#1
REVIEW
Kemal Ali Ger, Pablo Urrutia-Cordero, Paul C Frost, Lars-Anders Hansson, Orlando Sarnelle, Alan E Wilson, Miquel Lürling
As blooms of cyanobacteria expand and intensify in freshwater systems globally, there is increasing interest in their ecological effects. In addition to being public health hazards, cyanobacteria have long been considered a poor quality food for key zooplankton grazers that link phytoplankton to higher trophic levels. While past laboratory studies have found negative effects of nutritional constraints and defensive traits (i.e., toxicity and colonial or filamentous morphology) on the fitness of large generalist grazers (i...
April 2016: Harmful Algae
https://www.readbyqxmd.com/read/28073469/effect-of-the-toxin-microcystin-content-of-microcystis-on-copepod-grazing
#2
Kemal Ali Ger, Elisabeth J Faassen, Maria Grazia Pennino, Miquel Lürling
Although phytoplankton chemical defense may regulate plankton dynamics, demonstrating an ecologically relevant anti-grazer cue is challenging. Presented here is a novel approach to evaluate the quantitative effect of microcystin (MC), the most studied group of cyanobacterial metabolites, on grazing by the common copepod Eudiaptomus gracilis. A temperature-induced gradient in the intracellular MC concentration of three different Microcystis strains enabled the comparison of grazing pressure on cells of the same cyanobacterial strain producing different amounts of MC, in a diet with alternative food (Chlamydomonas)...
February 2016: Harmful Algae
https://www.readbyqxmd.com/read/28070626/nuclear-receptors-regulate-lipid-metabolism-and-oxidative-stress-markers-in-chondrocytes
#3
Anusha Ratneswaran, Margaret Man-Ger Sun, Holly Dupuis, Cynthia Sawyez, Nica Borradaile, Frank Beier
: Joint homeostasis failure can result in osteoarthritis (OA). Currently, there are no treatments to alter disease progression in OA, but targeting early changes in cellular behavior has great potential. Recent data show that nuclear receptors contribute to the pathogenesis of OA and could be viable therapeutic targets, but their molecular mechanisms in cartilage are incompletely understood. This study examines global changes in gene expression after treatment with agonists for four nuclear receptor implicated in OA (LXR, PPARδ, PPARγ, and RXR)...
January 9, 2017: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/28070003/pregnancy-hormonal-treatments-for-infertility-contraception-and-menopause-in-women-after-ischemic-stroke-a-consensus-document
#4
Valeria Caso, Alberto Falorni, Cheryl D Bushnell, Monica Acciarresi, José Remohí, Nikola Sprigg, Sandro Gerli
No abstract text is available yet for this article.
January 9, 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28069102/the-effect-of-cp-concentration-in-the-diet-on-urea-kinetics-and-microbial-usage-of-recycled-urea-in-cattle-a-meta-analysis
#5
E D Batista, E Detmann, S C Valadares Filho, E C Titgemeyer, R F D Valadares
In ruminants, urea recycling is considered an evolutionary advantage. The amount of urea recycled mainly depends of the nitrogen (N) intake and the amount of organic matter (OM) digested in the rumen. Because recycled N contributes to meeting microbial N requirements, accurate estimates of urea recycling can improve the understanding of efficiency of N utilization and N losses to the environment. The objective of this study was to evaluate urea kinetics and microbial usage of recycled urea N in ruminants using a meta-analytical approach...
January 10, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28061521/quality-of-life-after-surgical-treatment-for-esophageal-atresia-long-term-outcome-of-154-patients
#6
Alice Catherine Hölscher, Michael Laschat, Vera Choinitzki, Nadine Zwink, Ekkehart Jenetzky, Oliver Münsterer, Ralf Kurz, Marcus Pauly, Ulrike Brokmeier, Andreas Leutner, Benno Ure, Martin Lacher, Johannes Schumacher, Heiko Reutter, Thomas Michael Boemers
Background The short- and long-term surgical results in patients with esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) have been described in depth from a physician's perspective. Contrarily, the perception and coping strategies of affected patients and their parents have rarely been reported. The aim of this study was to generate data on this matter. Patients and Methods A total of 154 patients who had operative reconstruction for EA between 1971 and 2012 were evaluated for demographic data, surgical technique, affection of daily life, and coping strategies...
January 6, 2017: European Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28058943/genome-wide-analysis-of-blood-gene-expression-in-migraine-implicates-immune-inflammatory-pathways
#7
Zachary F Gerring, Joseph E Powell, Grant W Montgomery, Dale R Nyholt
Background Typical migraine is a frequent, debilitating and painful headache disorder with an estimated heritability of about 50%. Although genome-wide association (GWA) studies have identified over 40 single nucleotide polymorphisms associated with migraine, further research is required to determine their biological role in migraine susceptibility. Therefore, we performed a study of genome-wide gene expression in a large sample of 83 migraine cases and 83 non-migraine controls to determine whether altered expression levels of genes and pathways could provide insights into the biological mechanisms underlying migraine...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28056581/is-the-robson-s-classification-system-burdened-by-obstetric-pathologies-and-maternal-characteristics-and-assistential-levels-in-comparing-hospitals-cesarean-rates-a-regional-analysis-of-class-1-and-3
#8
Sandro Gerli, Alessandro Favilli, David Franchini, Marcello De Giorgi, Paola Casucci, Fabio Parazzini
OBJECTIVE: to assess if maternal risk profile and Hospital assistential levels were able to influence the inter-Hospitals comparison in the class 1 and 3 of the "The Ten Group Classification System" (TGCS). METHODS: a population-based analysis using data from Isititutional data-base of an Italian Region was carried out. The 11 maternity wards were divided into two categories: second-level hospitals (SLH), and first-level hospitals (FLH). The recorded deliveries were classified according to the TGCS...
January 6, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28054169/constitutive-expression-of-a-plant-ferredoxin-like-protein-pflp-enhances-capacity-of-photosynthetic-carbon-assimilation-in-rice-oryza-sativa
#9
Hsiang Chang, Hsiang-En Huang, Chin-Fu Cheng, Mei-Hsuan Ho, Mang-Jye Ger
The plant ferredoxin-like protein (PFLP) gene, cloned from sweet peppers predicted as an electron carrier in photosynthesis, shows high homology to the Fd-I sequence of Arabidopsis thaliana, Lycopersicon esculentum, Oryza sativa and Spinacia oleracea. Most of pflp related studies focused on anti-pathogenic effects, while less understanding for the effects in photosynthesis with physiological aspects, such as photosynthesis rate, and levels of carbohydrate metabolites. This project focuses on the effects of pflp overexpression on photosynthesis by physiological evaluations of carbon assimilation with significant higher levels of carbohydrates with higher photosynthesis efficiency...
January 4, 2017: Transgenic Research
https://www.readbyqxmd.com/read/28053883/curcumin-reverses-neurochemical-histological-and-immuno-histochemical-alterations-in-the-model-of-global-brain-ischemia
#10
Glaura Fernandes Teixeira de Alcântara, Eudes Simões-Neto, Giovany Michely Pinto da Cruz, Maria Elizabeth Pereira Nobre, Kelly Rose Tavares Neves, Geanne Matos de Andrade, Gerly Anne de Castro Brito, Glauce Socorro de Barros Viana
Curcumin, a curcuminoid from Curcuma longa, presents antioxidant and anti-inflammatory actions and, among pathological changes of cerebral ischemic injury, inflammation is an important one. The objectives were to study the neuroprotective action of curcumin, in a model of global ischemia. Male Wistar rats (sham-operated, ischemic untreated and ischemic treated with curcumin, 25 or 50 mg/kg, p.o.) were anesthesized and their carotid arteries occluded, for 30 min. The SO group had the same procedure, except for carotid occlusion...
January 2017: Journal of Traditional and Complementary Medicine
https://www.readbyqxmd.com/read/28051867/construction-of-the-azacyclic-core-of-tabernaemontanine-related-alkaloids-via-tandem-reformatsky-aza-claisen-rearrangement
#11
Young-Ger Suh, Changjin Lim, Jaehoon Sim, Jae Kyun Lee, Young-Joon Surh, Seung-Mann Paek
A divergent synthetic methodology for tabernaemontanine-related alkaloid was developed. The synthetic route features practical improvements in the Pictet-Spengler cyclization for the tetrahydro-beta-carboline intermediate and an unprecedented tandem Reformatsky-aza Claisen rearrangement to create the core carbon skeleton and stereochemistries of tabernaemontanine-related alkaloids.
January 4, 2017: Journal of Organic Chemistry
https://www.readbyqxmd.com/read/28049863/the-effect-of-acute-stress-on-esophageal-motility-and-gastroesophageal-reflux-in-healthy-humans
#12
Hong Sub Lee, Chung Kyun Noh, Kwang Jae Lee
Background/Aims: Little research has been done to evaluate the effect of stress in exacerbating the symptoms associated with gastroesophageal reflux (GER). We aimed to investigate the effect of acute stress on esophageal motility and GER parameters in healthy volunteers. Methods: A total of 10 (M:F = 8:2, median age 34 years-old) healthy volunteers without any recurrent gastrointestinal symptoms participated in this study. They underwent esophageal high-resolution manometry with 10 wet swallows (Experiment I) and esophageal impedance-pH monitoring (Experiment II) in the basal period and in the stress period...
January 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28046950/we-fg-202-12-investigation-of-longitudinal-salivary-gland-dce-mri-changes
#13
R Ger, M Awan, A Mohamed, Y Ding, S Frank, R Howell, H Li, H Liu, R Mohan, D Schellingerhout, R Stafford, J Wang, C Fuller, L Court
PURPOSE: To determine the correlation between dose and changes through treatment in dynamic contrast enhanced (DCE) MRI voxel parameters (Ktrans, kep, Ve, and Vp) within salivary glands of head and neck oropharyngeal squamous cell carcinoma (HNSCC) patients. METHODS: 17 HNSCC patients treated with definitive radiation therapy completed DCE-MRI scans on a 3T scanner at pre-treatment, mid-treatment, and post-treatment time points. Mid-treatment and post-treatment DCE images were deformably registered to pre-treatment DCE images (Velocity software package)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28032346/mannose-binding-lectin-and-l-ficolin-polymorphisms-in-patients-with-community-acquired-pneumonia-caused-by-intracellular-pathogens
#14
Gijs van Kempen, Sabine Meijvis, Hendrik Endeman, Bart Vlaminckx, Bob Meek, Ben de Jong, Ger T Rijkers, Willem Jan Bos
Community acquired pneumonia (CAP) is the leading infectious disease requiring hospitalisation in the Western World. Genetic variability affecting the host response to infection may play a role in susceptibility and outcome in CAP patients. Mannose binding lectin (MBL) and L-ficolin (L-FCN) are two important activators of the complement system and they can enhance phagocytosis by opsonisation. In a prospective cohort of 505 Dutch CAP patients and 227 controls we studied whether polymorphisms in the MBL (MBL2) and FCN (FCN2) genes influenced susceptibility and outcome...
December 29, 2016: Immunology
https://www.readbyqxmd.com/read/28028811/rapid-frequency-dependent-changes-in-free-mitochondrial-calcium-concentration-in-rat-cardiac-myocytes
#15
Rob Ci Wüst, Michiel Helmes, Jody L Martin, Thomas Jt van der Wardt, René Jp Musters, Jolanda van der Velden, Ger Jm Stienen
: Calcium ions regulate mitochondrial ATP production and contractile activity and thus play a pivotal role in matching energy supply and demand in cardiac muscle. Little is known about the magnitude and kinetics of the changes in free mitochondrial calcium concentration in cardiomyocytes. Using adenoviral infection, a ratiometric mitochondrially-targeted FRET-based calcium indicator (4 mtD3cpv, MitoCam) was expressed in cultured adult rat cardiomyocytes and the free mitochondrial calcium concentration ([Ca(2+) ]m ) was measured at different stimulation frequencies (0...
December 27, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/28025442/clinical-efficacy-of-a-1-matricaria-chamomile-l-mouthwash-and-0-12-chlorhexidine-for-gingivitis-control-in-patients-undergoing-orthodontic-treatment-with-fixed-appliances
#16
Paula Goes, Caio S Dutra, Mário R P Lisboa, Delane V Gondim, Renata Leitão, Gerly A C Brito, Rodrigo O Rego
This pilot study evaluated the clinical efficacy of a mouthwash containing 1% Matricaria chamomilla L. (MTC) extract in reducing gingival inflammation and plaque formation in patients undergoing orthodontic treatment with fixed appliances. This randomized, double-blind, placebo-controlled study enrolled a total of 30 males and females (age, 10-40 years) with fixed orthodontic appliances and a minimum of 20 natural teeth. The participants were allocated to three groups (n = 10 each) and asked to rinse with 15 mL of a placebo, 0...
2016: Journal of Oral Science
https://www.readbyqxmd.com/read/28024664/long-term-use-of-opioids-in-210-officially-registered-patients-with-chronic-noncancer-pain-in-taiwan-a-cross-sectional-study
#17
Tso-Chou Lin, Luo-Ping Ger, Joseph V Pergolizzi, Robert B Raffa, Ju-O Wang, Shung-Tai Ho
BACKGROUND/PURPOSE: Prescribing opioids for chronic noncancer pain has been strictly regulated for two decades in Taiwan. The aim of this study was to survey the patients' perspectives and potential drawbacks following long-term use of opioids. METHODS: An observational cross-sectional survey using the Taiwanese version of Brief Pain Inventory was conducted among outpatients with chronic noncancer pain registered by the Taiwan Food and Drug Administration. Patients were also asked about their sexual behavior, depression, opioid misuse behaviors, and use of complementary and alternative medicine...
December 23, 2016: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/28002097/associations-between-spatial-and-temporal-contrast-sensitivity-and-reading
#18
Tamara Brussee, Thomas J T P van den Berg, Ruth M A van Nispen, Ger H M B van Rens
PURPOSE: To gain insight into the association between optical and neural components of contrast sensitivity (CS), operationalized as spatial CS (optical and neural) or temporal CS (solely neural), and reading speed in a clinical sample of healthy adults of various ages. Furthermore, precision and agreement of the two methods were assessed. METHODS: The Mars test and the temporal CS implementation of the C-Quant device were used to measure spatial CS and temporal CS, respectively...
December 20, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27992033/patient-safety-culture-in-hospitals-within-the-nursing-perspective
#19
Greice Letícia Toso, Lidiane Golle, Tânia Solange Bosi de Souza Magnago, Gerli Elenise Gehrke Herr, Marli Maria Loro, Fabiele Aozane, Adriane Cristina Bernat Kolankiewicz
Objective: Evaluate the atmosphere regarding patient safety from the perspective of active nurses in hospitals in a country town of Rio Grande do Sul State. Methods: Cross-sectional study with 637 nursing professionals from two hospitals. Data collection through Safety Attitudes Questionnaire, in the second half of 2014. Cutoff for positive assessment was ≥75 points. Results: The scores for domains in the overall assessment were: 76 (team work atmosphere), 73 (safety atmosphere), 88 (job satisfaction), 59 (perceived stress), 66 (perception of unit management), 65 (perception of hospital management) and 80 (work conditions)...
December 15, 2016: Revista Gaúcha de Enfermagem
https://www.readbyqxmd.com/read/27987250/lung-disease-severity-in-idiopathic-pulmonary-fibrosis-is-more-strongly-associated-with-impedance-measures-of-bolus-reflux-than-ph-parameters-of-acid-reflux-alone
#20
S Gavini, L F Borges, R T Finn, W-K Lo, H J Goldberg, R Burakoff, N Feldman, W W Chan
BACKGROUND: Gastroesophageal reflux (GER) has been associated with idiopathic pulmonary fibrosis (IPF). Pathogenesis may be related to chronic micro-aspiration. We aimed to assess objective measures of GER on multichannel intraluminal impedance and pH study (MII-pH) and their relationship with pulmonary function testing (PFT) results, and to compare the performance of pH/acid reflux parameters vs corresponding MII/bolus parameters in predicting pulmonary dysfunction in IPF. METHODS: This was a retrospective cohort study of IPF patients undergoing prelung transplant evaluation with MII-pH off acid suppression, and having received PFT within 3 months...
December 16, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
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