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https://www.readbyqxmd.com/read/28931145/medical-and-psychological-problems-faced-by-young-australian-gap-year-travellers
#1
Luis Furuya-Kanamori, Deborah Mills, Sarah Sheridan, Colleen Lau
Background: Gap year travellers can potentially be exposed to many infectious diseases and other travel-related health problems including injuries and psychological problems. Currently, there is little information on health and wellbeing of this particular group of travellers. Methods: Participants were recruited from an organization that specialized in organising international gap year placements. Gap year travellers were asked to complete a pre-departure survey on demographics, placement destination and duration, previous travel experience, hobbies, risk taking behaviour, anticipated problems during the placement, and pre-travel preparations...
September 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28931026/does-physical-activity-buffer-insomnia-due-to-back-and-neck-pain
#2
Iben Axén, Lydia Kwak, Jan Hagberg, Irene Jensen
INTRODUCTION: Musculoskeletal pain is highly prevalent and a burden to society, recurrent and persistent low back pain (LBP) and neck pain (NP) being the most common conditions. They are associated with other poor health outcomes such as sleep problems. Physical activity (PA) prevents LBP and NP, but the direct effect on sleep is unclear. This study explored the effect of pain on insomnia, and examined if adherence to moderate-to-high intensity levels of PA influenced this relationship...
2017: PloS One
https://www.readbyqxmd.com/read/28930971/determination-of-the-optimal-chromosomal-location-s-for-a-dna-element-in-escherichia-coli-using-a-novel-transposon-mediated-approach
#3
Jakob Frimodt-Møller, Godefroid Charbon, Karen A Krogfelt, Anders Løbner-Olesen
The optimal chromosomal position(s) of a given DNA element was/were determined by transposon-mediated random insertion followed by fitness selection. In bacteria, the impact of the genetic context on the function of a genetic element can be difficult to assess. Several mechanisms, including topological effects, transcriptional interference from neighboring genes, and/or replication-associated gene dosage, may affect the function of a given genetic element. Here, we describe a method that permits the random integration of a DNA element into the chromosome of Escherichia coli and select the most favorable locations using a simple growth competition experiment...
September 11, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28930888/what-matters-most-to-whom-racial-ethnic-and-language-differences-in-the-health-care-experiences-most-important-to-patients
#4
Rebecca L Collins, Ann Haas, Amelia M Haviland, Marc N Elliott
BACKGROUND: Some aspects of patient experience are more strongly related to overall ratings of care than others, reflecting their importance to patients. However, little is known about whether the importance of different aspects of this experience differs across subgroups. OBJECTIVES: To determine whether the aspects of health care most important to patients differ according to patient race, ethnicity, and language preference. RESEARCH DESIGN: In response to the 2013 Medicare Consumer Assessment of Health Plans Study (CAHPS) survey, patients rated their overall health care and completed items measuring five patient experience domains...
September 19, 2017: Medical Care
https://www.readbyqxmd.com/read/28930607/transcriptomics-in-amyotrophic-lateral-sclerosis
#5
Marios G Krokidis, Panagiotis Vlamos
Amyotrophic lateral sclerosis (ALS) is an adult-onset, incurable neurodegenerative disease characterized by the selective death of upper and lowers motor neurons in the spinal cord, brainstem and motor cortex, which ultimately leads to paralysis and death within 2-3 years of onset. ALS is poorly understood, although multiple studies have been proposed to explain the pathophysiological mechanisms of the disorder. The development of microarray technology, for simultaneous analysis of the transcriptional expression of thousands of genes, has provided new possibilities to get better insights into the pathogenesis of ALS, and most important, potential new candidate targets for novel treatments...
January 1, 2018: Frontiers in Bioscience (Elite Edition)
https://www.readbyqxmd.com/read/28930157/getting-more-power-from-your-flowers-multi-functional-flower-strips-enhance-pollinators-and-pest-control-agents-in-apple-orchards
#6
Alistair John Campbell, Andrew Wilby, Peter Sutton, Felix Wäckers
Flower strips are commonly recommended to boost biodiversity and multiple ecosystem services (e.g., pollination and pest control) on farmland. However, significant knowledge gaps remain regards the extent to which they deliver on these aims. Here, we tested the efficacy of flower strips that targeted different subsets of beneficial arthropods (pollinators and natural enemies) and their ecosystem services in cider apple orchards. Treatments included mixes that specifically targeted: (1) pollinators ('concealed-nectar plants'); (2) natural enemies ('open-nectar plants'); or (3) both groups concurrently (i...
September 20, 2017: Insects
https://www.readbyqxmd.com/read/28930108/terra-firma-forme-dermatosis-misdiagnosed-as-nevoid-acanthosis-nigricans
#7
Gulsen Tukenmez Demirci, Ayse Tulin Mansur, Ebru Demiralay
Terra firma-forme dermatosis (TFFD) is a clinical condition characterized by brown-gray, velvety, pigmented patches or plaques, resembling dirt on the skin. Nevoid acanthosis nigricans (NAN) is a rare and recently described form of acanthosis nigricans occurring during childhood or early adulthood. Herein we describe a patient with TFFD, initially misdiagnosed as NAN. The patient had developed hyperkeratotic and hyperpigmented plaques on and around the umbilicus during pregnancy. Though regular in bathing practices, she could not clear away the lesions and concerned marks for inesthetic appearance...
October 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28930068/risk-for-alcohol-exposed-pregnancies-among-women-at-drinking-venues-in-cape-town-south-africa
#8
Melissa H Watt, Brandon A Knettel, Karmel W Choi, Elizabeth T Knippler, Philip A May, Soraya Seedat
OBJECTIVE: South Africa's Western Cape Province has one of the highest rates of fetal alcohol spectrum disorder globally. Alcohol-serving venues are likely important sites to identify women at high risk of having a child with fetal alcohol spectrum disorder. The goal of this study was to examine the risk for alcohol-exposed pregnancies among women who drink in alcohol-serving venues. METHOD: Cross-sectional surveys were conducted with 200 women of reproductive age at seven drinking venues in a single Cape Town community...
September 2017: Journal of Studies on Alcohol and Drugs
https://www.readbyqxmd.com/read/28929945/innovative-pcr-without-dna-extraction-for-african-sickle-cell-disease-diagnosis
#9
L Detemmerman, S Olivier, V Bours, F Boemer
OBJECTIVES: Hemoglobin (Hb) disorders consist of thalassemia and Hb structural variants, of which the major forms are associated with severe anemia and/or vascular occlusion. Current diagnostic techniques are highly accurate and mostly based on isoelectric focusing, high-performance liquid chromatography or mass spectrometry, which often require advanced laboratory equipment. In sub-Saharan Africa, the Hb disorders are mainly associated to the pathological variants hemoglobin S (HbS) and HbC...
September 20, 2017: Hematology (Amsterdam, Netherlands)
https://www.readbyqxmd.com/read/28929914/the-conundrum-of-opioid-tapering-in-long-term-opioid-therapy-for-chronic-pain-a-commentary
#10
Ajay Manhapra, Albert A Arias, Jane C Ballantyne
BACKGROUND: In response to the opioid epidemic and new guidelines, many patients on high-dose long term opioid therapy (LTOT) for chronic pain are getting tapered off opioids. As a result, a unique clinical challenge is emerging: while many on LTOT have poor pain control, functional decline, psychiatric instability, aberrancies and misuse, these issues may often worsen with opioid tapering. Currently, a clear explanation and practical guidance on how to manage this perplexing clinical scenario is lacking...
September 20, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28929883/managing-environmental-sustainability-in-a-healthcare-setting
#11
Karen Langstaff, Victoria Brzozowski
How does a hospital sustain its journey towards environmental sustainability? To date, most hospitals have embarked on some strategies for improving environmental performance, whether it's reducing energy or landfill waste. Environmental sustainability strategies, however, can often lose momentum or stagnate if not championed by someone whose full-time role is to assess, monitor, and bring new strategies to the table. In the face of ongoing budget deficits, it is increasingly difficult to get adequate support and buy-in for this type of role unless the leadership of the organization is committed to an environmental sustainability program...
March 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28929869/pharmacare-are-we-getting-the-right-medicines
#12
Gail Attara
Canada is the only country in the world with a national healthcare plan that does not include drug coverage. Coverage of necessary medications is a patchwork of inconsistent programs that does not always serve the very individuals it was created to help-those patients who need prescribed medicines. Our system needs radical, intuitive changes.
July 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28929784/investigating-children-s-perception-of-nurses-through-their-drawings
#13
Nazan Çakirer Çalbayram, Sebahat Altundağ, Bahise Aydin
Hospitalized children can have various fantasies about hospital, health staff, and related tools and equipment. They need to develop new coping strategies for compliance with hospitalization.This study aimed to investigate the perception of nurses by children with acute and chronic illness through their drawings. The study was carried out using a descriptive research model. "Nurses through the eyes of sick children data collection form" was used in data collection procedure. The instruction "draw a picture of a nurse, please" was used to get the children to draw a picture...
September 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/28929252/knowledge-about-cervical-cancer-risk-factors-and-practices-of-pap-testing-among-turkish-immigrant-women-in-the-united-states
#14
Aynur Uysal Toraman, Nilufer Yildirim
The objective of this study was to examine knowledge about cervical cancer risk factors and practices of Pap testing among female Turkish immigrants in the state of Florida in the United States of America (USA). This descriptive study was conducted between April and September 2012. The study sampling was consist of 156 Turkish women living in the state of Florida. A questionnaire-based survey was conducted among the population of Turkish immigrant women. On the survey form comprised of a total of 37 questions and three sections there are questions pertaining to the socio-demographic characteristics of the individuals, their knowledge on the cervical cancer risk factors and their approach to getting Pap smear tests...
September 19, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28929046/application-of-three-dimensional-printing-for-colon-targeted-drug-delivery-systems
#15
REVIEW
Nitin B Charbe, Paul A McCarron, Majella E Lane, Murtaza M Tambuwala
Orally administered solid dosage forms currently dominate over all other dosage forms and routes of administrations. However, human gastrointestinal tract (GIT) poses a number of obstacles to delivery of the drugs to the site of interest and absorption in the GIT. Pharmaceutical scientists worldwide have been interested in colon drug delivery for several decades, not only for the delivery of the drugs for the treatment of colonic diseases such as ulcerative colitis and colon cancer but also for delivery of therapeutic proteins and peptides for systemic absorption...
April 2017: International Journal of Pharmaceutical Investigation
https://www.readbyqxmd.com/read/28928947/puzzles-in-modern-biology-v-why-are-genomes-overwired
#16
Steven A Frank
Many factors affect eukaryotic gene expression. Transcription factors, histone codes, DNA folding, and noncoding RNA modulate expression. Those factors interact in large, broadly connected regulatory control networks. An engineer following classical principles of control theory would design a simpler regulatory network. Why are genomes overwired? Neutrality or enhanced robustness may lead to the accumulation of additional factors that complicate network architecture. Dynamics progresses like a ratchet. New factors get added...
2017: F1000Research
https://www.readbyqxmd.com/read/28928913/quality-of-life-in-elderly-iranian-population-using-leiden-padua-questionnaire-a-systematic-review-and-meta-analysis
#17
REVIEW
Parvin Cheraghi, Zahra Cheraghi, Amin Doosti-Irani, Sima Nedjat, Saharnaz Nedjat
The world population is getting old rapidly; the aging population is the new phenomenon in Iran too. The aim of this meta-analysis was to estimate the overall and subscales mean score of quality of life (QOL) based on the Leiden-Padua (LEIPAD) questionnaire among the elderly population of Iran. The major international and national databases including; Medlin, Scopus, Science Direct, SID, MagIran, IranMedex, and Irandoc was searched. All cross-sectional studies, which measured the QOL among the elderly population in Iran using the LEIPAD questionnaire, were included...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28928909/transplanting-embryonic-stem-cells-onto-damaged-human-corneal-endothelium
#18
Charles Hanson, Arsaell Arnarsson, Thorir Hardarson, Ann Lindgård, Mandana Daneshvarnaeini, Catarina Ellerström, Anita Bruun, Ulf Stenevi
AIM: To investigate whether human embryonic stem cells (hESCs) could be made to attach, grow and differentiate on a human Descemet's membrane (DM). METHODS: Spontaneously differentiated hESCs were transferred onto a human corneal button with the endothelial layer removed using ocular sticks. The cells were cultured on a DM for up to 15 d. The genetically engineered hESC line expressed green fluorescent protein, which facilitated identification during the culture experiments, tissue preparation, and analysis...
August 26, 2017: World Journal of Stem Cells
https://www.readbyqxmd.com/read/28928590/arteriovenous-malformation-of-face-a-challenge-to-anesthesiologists
#19
S Neeta, Rammoorthi Rao, Madhusudan Upadya, P Keerthi
Arteriovenous (AV) malformations of the face are rare presentations. Endovascular coiling is one of the treatment modalities. We report a case of a 65-year-old lady who presented with a large AV malformation of the face located around the nasal bride and alae nasae posted for coiling under general anesthesia. Anesthetic management of the case was a challenge as it was an anticipated difficult airway situation. Furthermore, any pressure on the swelling can lead to rupture and hemorrhage as the skin above swelling was unhealthy...
July 2017: Anesthesia, Essays and Researches
https://www.readbyqxmd.com/read/28928312/getting-real-with-the-upcoming-challenge-of-electronic-nicotine-delivery-systems-the-way-forward-for-the-south-east-asia-region
#20
REVIEW
Jagdish Kaur, Arvind Vashishta Rinkoo
Electronic nicotine delivery systems (ENDS) are being marketed to tobacco smokers for use in places where smoking is not allowed or as aids similar to pharmaceutical nicotine products to help cigarette smokers quit tobacco use. These are often flavored to make them more attractive for youth - ENDS use may lead young nonsmokers to take up tobacco products. Neither safety nor efficacy as a cessation aid of ENDS has been scientifically demonstrated. The adverse health effects of secondhand aerosol cannot be ruled out...
September 2017: Indian Journal of Public Health
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