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Non pharmacologic treatment of ADHD

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https://www.readbyqxmd.com/read/28465719/italian-regional-health-service-costs-for-diagnosis-and-1-year-treatment-of-adhd-in-children-and-adolescents
#1
Gianluigi Casadei, Massimo Cartabia, Laura Reale, Maria Antonella Costantino, Maurizio Bonati
The main aim of this study was to estimate the costs associated with diagnostic assessment and 1-year therapy in children and adolescents enrolled in 18 ADHD reference centres. Data concerning 1887 children and adolescents from the mandatory ADHD registry database during the 2012-2014 period were analysed. The overall diagnostic and treatment costs per patient amounts to €574 and €830, respectively. The ADHD centre, the school as sender, and the time to diagnosis constitute cost drivers. Non-pharmacological therapy resulted as being more expensive for patients concomitantly treated with drugs (€929) compared to those treated with psychological interventions alone (€590; p = 0...
2017: International Journal of Mental Health Systems
https://www.readbyqxmd.com/read/28391109/attention-deficit-hyperactivity-disorder-and-substance-abuse-an-investigation-in-young-austrian-males
#2
Anita Riegler, Sabine Völkl-Kernstock, Otto Lesch, Henriette Walter, Katrin Skala
BACKGROUND: Many studies have found an association between Substance Use Disorders (SUDs) and Attention Deficit Hyperactivity Disorder (ADHD) in children, adolescents and adults. We intended to determine whether substance abuse and SUDs are associated with former and current ADHD symptomatology in a non-clinical sample of 17 and 18 year old males. METHOD: A representative sample of 3280 young men (6.8% of all males born in Austria in the respective year) was investigated during the examination for military service...
April 4, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28280346/trend-characteristics-and-pharmacotherapy-of-adults-diagnosed-with-attention-deficit-hyperactivity-disorder-a-nationwide-survey-in-taiwan
#3
Yu-Shian Cheng, Yu-Chiau Shyu, Sheng-Yu Lee, Shin-Sheng Yuan, Chun-Ju Yang, Kang-Chung Yang, Tung-Liang Lee, Liang-Jen Wang
OBJECTIVE: Attention-deficit/hyperactivity disorder (ADHD) in adults may result in functional impairment warranting clinical interventions. However, few studies have investigated the diagnosis and treatment rates of adult ADHD in non-Caucasian ethnic groups. This study used nationwide population-based data to investigate the rate of diagnosis, associated characteristics, and pharmacological treatment for adult ADHD in Taiwan. METHODS: Adults (age ≥18 years) newly diagnosed with ADHD (n=5,397) between January 2000 and December 2011 were enrolled from the National Health Insurance database in Taiwan...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28265323/bladder-and-bowel-dysfunction-in-children-an-update-on-the-diagnosis-and-treatment-of-a-common-but-underdiagnosed-pediatric-problem
#4
REVIEW
Joana Dos Santos, Roberto I Lopes, Martin A Koyle
Bladder and bowel dysfunction (BBD) describes a spectrum of lower urinary symptoms (LUTS) accompanied by fecal elimination issues that manifest primarily by constipation and/or encopresis. This increasingly common entity is a potential cause of significant physical and psychosocial burden for children and families. BBD is commonly associated with vesicoureteral reflux (VUR) and recurrent urinary tract infections (UTIs), which at its extreme may lead to renal scarring and kidney failure. Additionally, BBD is frequently seen in children diagnosed with behavioural and neuropsychiatric disorders such as attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD)...
January 2017: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/28258319/comparative-efficacy-and-safety-of-attention-deficit-hyperactivity-disorder-pharmacotherapies-including-guanfacine-extended-release-a-mixed-treatment-comparison
#5
REVIEW
Alain Joseph, Rajeev Ayyagari, Meng Xie, Sean Cai, Jipan Xie, Michael Huss, Vanja Sikirica
This study compared the clinical efficacy and safety of attention-deficit/hyperactivity disorder (ADHD) pharmacotherapy in children and adolescents 6-17 years of age. A systematic literature review was conducted to identify randomized controlled trials (RCTs) of pharmacologic monotherapies among children and adolescents with ADHD. A Bayesian network meta-analysis was conducted to compare change in symptoms using the ADHD Rating Scale Version IV (ADHD-RS-IV), Clinical Global Impression-Improvement (CGI-I) response, all-cause discontinuation, and adverse event-related discontinuation...
March 3, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28256680/-treatments-for-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-what-is-the-evidence-base-to-date
#6
S Cortese, R Rosello-Miranda
The evidence base from empirical studies is one of the elements, along with patients' preference and consideration of particular clinical state and circumstances, that should be taken into account in the process of clinical decision making. This paper provides an overview of the current evidence base for the treatment of attention-deficit-hyperactivity disorder (ADHD), drawing on the results of the most recent meta-analyses of randomized controlled trials assessing the pharmacological and non-pharmacological treatment of ADHD...
February 24, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28110366/atomoxetine-treatment-for-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-adhd-a-comprehensive-meta-analysis-of-outcomes-on-parent-rated-core-symptomatology
#7
REVIEW
Jessica L Gayleard, Matthew P Mychailyszyn
Attention-Deficit/Hyperactivity Disorder (ADHD) impacts a significant number of children and adolescents and often leads to deleterious functional impairment. Psychostimulant medication has historically been the first line of pharmacological intervention, though recent years have seen greater attention paid to non-stimulant alternatives. The objective of the present study was to conduct the most comprehensive meta-analysis to date evaluating the efficacy of atomoxetine in reducing core symptomatology of ADHD according to parent report...
January 21, 2017: Attention Deficit and Hyperactivity Disorders
https://www.readbyqxmd.com/read/27993933/pharmacological-and-non-pharmacological-treatment-of-adults-with-adhd-a-meta-review
#8
Franco De Crescenzo, Samuele Cortese, Nicoletta Adamo, Luigi Janiri
Attention-deficit/hyperactivity disorder (ADHD) is characterised by a persistent and impairing pattern of inattention and/or hyperactivity/impulsivity and it is one of the most common neuropsychiatric conditions. Evidence about interventions of adults with ADHD is growing rapidly and clinicians need a reliable summary of all the best available information in order to better inform their daily practice. We searched MEDLINE, PubMed, PsycINFO and Cochrane databases until 31 May 2016 for systematic reviews about pharmacological and non-pharmacological treatments in adults with ADHD and carried out a meta-review to address clinically relevant questions...
February 2017: Evidence-based Mental Health
https://www.readbyqxmd.com/read/27863315/positive-effects-of-transcranial-direct-current-stimulation-in-adult-patients-with-attention-deficit-hyperactivity-disorder-a-pilot-randomized-controlled-study
#9
Carolina Tosetto Cachoeira, Douglas Teixeira Leffa, Suzana Doneda Mittelstadt, Lorenna Sena Teixeira Mendes, Andre R Brunoni, Jairo Vinicius Pinto, Vítor Blazius, Vitoria Machado, Claiton Henrique Dotto Bau, Luis Augusto Rohde, Eugenio Horacio Grevet, Pedro Schestatsky
Almost 30% of adult patients with attention-deficit/hyperactivity disorder (ADHD) do not respond or tolerate standard pharmacological interventions. Few clinical investigations addressed the efficacy and tolerability of transcranial direct current stimulation (tDCS), a non-invasive neuromodulatory technique, in the disorder. We performed a double-blind, sham-controlled randomized clinical trial in 17 patients with ADHD. The set up for tDCS was the following: 2mA/20min/day for 5 days with the anode over the right dorsolateral prefrontal cortex and cathode over the left dorsolateral prefrontal cortex...
January 2017: Psychiatry Research
https://www.readbyqxmd.com/read/27743498/adaptive-skills-are-useful-for-evaluating-the-effect-of-pharmacological-treatment-in-children-with-attention-deficit-hyperactivity-disorder
#10
Ida Lindblad, Salmir Nasic, Magnus Landgren, Leif Svensson, Christopher Gillberg, Elisabeth Fernell
AIM: There are few long-term studies of adaptive functions as an outcome measure of pharmacological treatment in attention-deficit/hyperactivity disorder (ADHD). This study assessed the adaptive abilities of children with ADHD before and after several years of pharmacological treatment. METHOD: We studied 12 children with a mean age of 15 years - seven boys and five girls - who had continued pharmacological treatment for ADHD for more than four years. The Adaptive Behaviour Assessment Scales - Second Edition ratings by their teachers were compared before and after they had received treatment for ADHD...
January 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/27659116/neurofeedback-training-effects-on-inhibitory-brain-activation-in-adhd-a-matter-of-learning
#11
Sarah Baumeister, Isabella Wolf, Nathalie Holz, Regina Boecker-Schlier, Nicoletta Adamo, Martin Holtmann, Matthias Ruf, Tobias Banaschewski, Sarah Hohmann, Daniel Brandeis
Neurofeedback training (NF) is a promising non-pharmacological treatment for ADHD that has been associated with improvement of attention-deficit/hyperactivity disorder (ADHD)-related symptoms as well as changes in electrophysiological measures. However, the functional localization of neural changes following NF compared to an active control condition, and of successful learning during training (considered to be the critical mechanism for improvement), remains largely unstudied. Children with ADHD (N=16, mean age: 11...
September 19, 2016: Neuroscience
https://www.readbyqxmd.com/read/27624381/use-of-psychotropic-drugs-in-patients-with-autism-spectrum-disorders-a-systematic-review
#12
REVIEW
K Jobski, J Höfer, F Hoffmann, C Bachmann
OBJECTIVE: The objective of this review was to examine prevalence and patterns of psychopharmacotherapy in individuals with autism spectrum disorder (ASD). METHOD: A systematic literature search in PubMed, CINAHL, and PsycINFO was performed, including articles published up to November 18, 2015. RESULTS: A total of 47 studies (data collection: 1976-2012), encompassing >300 000 individuals with ASD, were included. The prevalence of psychopharmacotherapy ranged from 2...
January 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/27453697/a-review-of-pharmacological-management-of-attention-deficit-hyperactivity-disorder
#13
REVIEW
Leslie Briars, Timothy Todd
Attention-deficit/hyperactivity disorder (ADHD) is a common psychological diagnosis in children. This disorder impacts children and adolescents in all areas of life, including academic performance, extracurricular activities, and social interactions. ADHD can continue into adulthood where unemployment and substance abuse has been described. Although behavioral therapy is recommended for all patients with ADHD, medication management typically is initiated soon after diagnosis. Psychostimulants remain the primary medication of choice...
May 2016: Journal of Pediatric Pharmacology and Therapeutics: JPPT: the Official Journal of PPAG
https://www.readbyqxmd.com/read/27445873/mindfulness-based-cognitive-therapy-and-the-adult-adhd-brain-a-neuropsychotherapeutic-perspective
#14
Katharina Bachmann, Alexandra P Lam, Alexandra Philipsen
Attention-deficit/hyperactivity disorder (ADHD) is a recognized serious mental disorder that often persists into adulthood. The symptoms and impairments associated with ADHD often cause significant mental suffering in affected individuals. ADHD has been associated with abnormal neuronal activity in various neuronal circuits, such as the dorsofrontostriatal, orbitofrontostriatal, and frontocerebellar circuits. Psychopharmacological treatment with methylphenidate hydrochloride is recommended as the first-line treatment for ADHD...
2016: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/27373215/evaluating-use-of-higher-dose-oxybutynin-in-combination-with-desmopressin-for-refractory-nocturnal-enuresis
#15
Aaron Berkenwald, Jacqueline Pires, Pamela Ellsworth
INTRODUCTION: Nocturnal enuresis is a common pediatric condition with limited treatment options. In older children, pharmacologic therapy is often the preferred treatment. Pharmacologic therapies including desmopressin (DDAVP) or imipramine are effective in 40-50% of children. However, imipramine has serious safety concerns. Desmopressin in combination with a fixed dose anticholinergic has been shown to be useful in individuals who fail desmopressin monotherapy, but still fails to achieve success rates greater than 60%...
August 2016: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/27103462/clinical-and-neurobiological-factors-in-the-management-of-treatment-refractory-attention-deficit-hyperactivity-disorder
#16
REVIEW
Se-Hoon Shim, Hee-Jung Yoon, Jeongjae Bak, Sang-Woo Hahn, Yong-Ku Kim
Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent mental disorder of childhood, which often continues into adolescence and adulthood. Stimulants such as methylphenidate (MPH) and non-stimulants such as atomoxetine are effective medications for the treatment of ADHD. However, about 30% of patients do not respond to these medications. Pharmacological treatment for ADHD, although highly effective, is associated with marked variabilities in clinical response, optimal dosage needed and tolerability...
October 3, 2016: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/26892760/centrally-acting-non-narcotic-antitussives-prevent-hyperactivity-in-mice-involvement-of-girk-channels
#17
Fumio Soeda, Yoshiko Fujieda, Mizue Kinoshita, Tetsuya Shirasaki, Kazuo Takahama
We have previously reported that centrally acting non-narcotic antitussives inhibited G protein-coupled inwardly rectifying potassium (GIRK) channel-activated currents, and that the antitussives had multiple pharmacological actions on various models of intractable brain diseases in rodents. In this study, the question of whether these antitussives inhibit drug-induced hyperactivity in mice was investigated. Antitussives, such as cloperastine and tipepidine, at cough suppressant doses, inhibited an increase in ambulation of mice neonatally treated with 6-hydroxydopamine...
May 2016: Pharmacology, Biochemistry, and Behavior
https://www.readbyqxmd.com/read/26837866/a-6-year-follow-up-of-a-large-european-cohort-of-children-with-attention-deficit-hyperactivity-disorder-combined-subtype-outcomes-in-late-adolescence-and-young-adulthood
#18
Marloes van Lieshout, Marjolein Luman, Jos W R Twisk, Hanneke van Ewijk, Annabeth P Groenman, Andrieke J A M Thissen, Stephen V Faraone, Dirk J Heslenfeld, Catharina A Hartman, Pieter J Hoekstra, Barbara Franke, Jan K Buitelaar, Nanda N J Rommelse, Jaap Oosterlaan
There are very few studies on the long-term outcome of children and adolescents with ADHD-combined type in Europe. The objective of the present study is to assess the 6-year outcome (including pharmacological treatment) of a large cohort of participants with ADHD-combined type (N = 347, mean age 11.4 years) in late adolescence and early adulthood. At study entry and follow-up (mean age 17.4 years), participants were comprehensively assessed on ADHD and comorbid disorders by structured psychiatric interviews and multi-informant questionnaires...
September 2016: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/26656767/rearing-in-an-enriched-environment-attenuated-hyperactivity-and-inattention-in-the-spontaneously-hypertensive-rats-an-animal-model-of-attention-deficit-hyperactivity-disorder
#19
Chrislean Jun Botanas, Hyelim Lee, June Bryan de la Peña, Irene Joy Dela Peña, Taeseon Woo, Hee Jin Kim, Doug Hyun Han, Bung-Nyun Kim, Jae Hoon Cheong
Attention-deficit hyperactivity disorder (ADHD) is a prevalent neurodevelopmental disorder, characterized by symptoms of hyperactivity, inattention, and impulsivity. It is commonly treated with psychostimulants that typically begins during childhood and lasts for an extended period of time. However, there are concerns regarding the consequences of chronic psychostimulant treatment; thus, there is a growing search for an alternative management for ADHD. One non-pharmacological management that is gaining much interest is environmental enrichment...
March 1, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/26599576/methylphenidate-for-children-and-adolescents-with-attention-deficit-hyperactivity-disorder-adhd
#20
REVIEW
Ole Jakob Storebø, Erica Ramstad, Helle B Krogh, Trine Danvad Nilausen, Maria Skoog, Mathilde Holmskov, Susanne Rosendal, Camilla Groth, Frederik L Magnusson, Carlos R Moreira-Maia, Donna Gillies, Kirsten Buch Rasmussen, Dorothy Gauci, Morris Zwi, Richard Kirubakaran, Bente Forsbøl, Erik Simonsen, Christian Gluud
BACKGROUND: Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed and treated psychiatric disorders in childhood. Typically, children with ADHD find it difficult to pay attention, they are hyperactive and impulsive.Methylphenidate is the drug most often prescribed to treat children and adolescents with ADHD but, despite its widespread use, this is the first comprehensive systematic review of its benefits and harms. OBJECTIVES: To assess the beneficial and harmful effects of methylphenidate for children and adolescents with ADHD...
November 25, 2015: Cochrane Database of Systematic Reviews
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