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https://www.readbyqxmd.com/read/27921226/the-relationship-between-aerosol-particles-chemical-composition-and-optical-properties-to-identify-the-biomass-burning-contribution-to-fine-particles-concentration-a-case-study-for-s%C3%A3-o-paulo-city-brazil
#1
Regina Maura de Miranda, Fabio Lopes, Nilton Évora do Rosário, Marcia Akemi Yamasoe, Eduardo Landulfo, Maria de Fatima Andrade
The air quality in the Metropolitan Area of São Paulo (MASP) is primarily determined by the local pollution source contribution, mainly the vehicular fleet, but there is a concern about the role of remote sources to the fine mode particles (PM2.5) concentration and composition. One of the most important remote sources of atmospheric aerosol is the biomass burning emissions from São Paulo state's inland and from the central and north portions of Brazil. This study presents a synergy of different measurements of atmospheric aerosol chemistry and optical properties in the MASP in order to show how they can be used as a tool to identify particles from local and remote sources...
December 2016: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/27917071/a-distinct-source-and-differentiation-history-for-kolumbo-submarine-volcano-santorini-volcanic-field-aegean-arc
#2
Martijn Klaver, Steven Carey, Paraskevi Nomikou, Ingrid Smet, Athanasios Godelitsas, Pieter Vroon
This study reports the first detailed geochemical characterization of Kolumbo submarine volcano in order to investigate the role of source heterogeneity in controlling geochemical variability within the Santorini volcanic field in the central Aegean arc. Kolumbo, situated 15 km to the northeast of Santorini, last erupted in 1650 AD and is thus closely associated with the Santorini volcanic system in space and time. Samples taken by remotely-operated vehicle that were analyzed for major element, trace element and Sr-Nd-Hf-Pb isotope composition include the 1650 AD and underlying K2 rhyolitic, enclave-bearing pumices that are nearly identical in composition (73 wt...
August 2016: Geochemistry, Geophysics, Geosystems: G³
https://www.readbyqxmd.com/read/27916677/differential-copper-binding-to-alpha-synuclein-and-its-disease-associated-mutants-affect-the-aggregation-and-amyloid-formation
#3
Priyatosh Ranjan, Dhiman Ghosh, Deepthi S Yarramala, Subhadeep Das, Samir K Maji, Ashutosh Kumar
BACKGROUND: Copper is an essential trace element required for the proper functioning of various enzymes present in central nervous system. An imbalance in the copper homeostasis results in the pathology of various neurogenerative disorders including Parkinson's Disease. Hence, residue specific interaction of Cu(2+) to α-Syn along with the familial mutants H50Q and G51D needs to be studied in detail. METHODS: We investigated the residue specific mapping of Cu(2+) binding sites and binding strength using solution-state NMR and ITC respectively...
December 1, 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27916303/seasonal-variation-of-particle-induced-oxidative-potential-of-airborne-particulate-matter-in-beijing
#4
Longyi Shao, Ying Hu, Rongrong Shen, Klaus Schäfer, Jing Wang, Jianying Wang, Jürgen Schnelle-Kreis, Ralf Zimmermann, Kelly BéruBé, Peter Suppan
An in vitro plasmid scission assay (PSA), the cell apoptosis assay, and ICP-MS were employed to study the oxidative potentials and trace element compositions of the airborne particulate matter (PM) in Beijing during a one year-long field campaign from June 2010 to June 2011. The cell damages induced by PM reveled by the cell apoptosis assay showed a similar variation pattern to the DNA damages obtained by PSA, verifying the feasibility of the PSA in analyzing the oxidative capacity of PM samples. The PSA experiments showed that the particle-induced DNA damage was highest in summer, followed by spring, winter and autumn in descending order...
December 1, 2016: Science of the Total Environment
https://www.readbyqxmd.com/read/27915676/dietary-exposure-to-trace-elements-and-health-risk-assessment-in-the-region-of-valencia-spain-a-total-diet-study
#5
Silvia Marín, Olga Pardo, Rosario Báguena, Guillermina Font, Vicent Yusà
Dietary exposure of the Valencian Region population to lead, cadmium, inorganic arsenic (iAs), chromium, copper, tin and methylmercury (meHg) was assessed in a Total Diet Study carried out in the Region of Valencia in 2010-2011. A total of 8100 food samples were collected and analysed. Occurrence data were combined with consumption data to estimate dietary exposure in adults (>15 years of age) and young children (6-15 years of age). The estimated intake was calculated by a probabilistic approach. Average intake levels (optimistic scenario) for lead, inorganic arsenic (iAs), chromium and tin were 0...
December 5, 2016: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/27914280/trace-isotope-analysis-of-ricinus-communis-seed-core-for-provenance-determination-by-laser-ablation-icp-ms
#6
Christina K Bagas, Rachel L Scadding, Cameron J Scadding, R John Watling, Warren Roberts, Simon P B Ovenden
The castor bean plant, Ricinus communis, grows wild throughout many regions of Australia. The seeds of the plant contain the schedule 1 chemical agent ricin, a type II ribosomal inhibiting protein. Currently there are limited analytical techniques that can be applied in analysis of the seeds to establish attribution. In this study, laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) was used for the analysis of seeds collected from 68 plants across 38 locations around Australia. Of the 92 elemental isotopes measured, fifteen ((24)Mg, (27)Al, (44)Ca, (53)Cr, (55)Mn, (57)Fe, (60)Ni, (65)Cu, (66)Zn, (75)As, (85)Rb, (88)Sr, (98)Mo, (138)Ba and (202)Hg) yielded data that were relevant to all collection sites...
November 25, 2016: Forensic Science International
https://www.readbyqxmd.com/read/27914278/fdstools-a-software-package-for-analysis-of-massively-parallel-sequencing-data-with-the-ability-to-recognise-and-correct-str-stutter-and-other-pcr-or-sequencing-noise
#7
Jerry Hoogenboom, Kristiaan J van der Gaag, Rick H de Leeuw, Titia Sijen, Peter de Knijff, Jeroen F J Laros
Massively parallel sequencing (MPS) is on the advent of a broad scale application in forensic research and casework. The improved capabilities to analyse evidentiary traces representing unbalanced mixtures is often mentioned as one of the major advantages of this technique. However, most of the available software packages that analyse forensic short tandem repeat (STR) sequencing data are not well suited for high throughput analysis of such mixed traces. The largest challenge is the presence of stutter artefacts in STR amplifications, which are not readily discerned from minor contributions...
November 27, 2016: Forensic Science International. Genetics
https://www.readbyqxmd.com/read/27913844/global-dna-methylation-profiling-of-manganese-exposed-human-neuroblastoma-sh-sy5y-cells-reveals-epigenetic-alterations-in-parkinson-s-disease-associated-genes
#8
Prashant Tarale, Saravanadevi Sivanesan, Atul P Daiwile, Reinhard Stöger, Amit Bafana, Pravin K Naoghare, Devendra Parmar, Tapan Chakrabarti, Krishnamurthi Kannan
Manganese (Mn) is an essential trace element required for optimal functioning of cellular biochemical pathways in the central nervous system. Elevated exposure to Mn through environmental and occupational exposure can cause neurotoxic effects resulting in manganism, a condition with clinical symptoms identical to idiopathic Parkinson's disease. Epigenetics is now recognized as a biological mechanism involved in the etiology of various diseases. Here, we investigated the role of DNA methylation alterations induced by chronic Mn (100 µM) exposure in human neuroblastoma (SH-SY5Y) cells in relevance to Parkinson's disease...
December 2, 2016: Archives of Toxicology
https://www.readbyqxmd.com/read/27911936/serum-calcium-magnesium-zinc-and-copper-levels-in-sudanese-women-with-preeclampsia
#9
Abdelmageed Elmugabil, Hamdan Z Hamdan, Anas E Elsheikh, Duria A Rayis, Ishag Adam, Gasim I Gasim
BACKGROUND: Although the exact pathophysiology of preeclampsia is not fully understood, several elemental micronutrient abnormalities have been suggested to play a contributory role in preeclampsia. AIMS: To investigate the levels of calcium, magnesium, zinc and copper in women with preeclampsia. SUBJECTS AND METHODS: A case-control study was conducted in Omdurman Maternity Hospital, Sudan, during the period of September through December 2014...
2016: PloS One
https://www.readbyqxmd.com/read/27911670/quantitative-assessment-of-metal-elements-using-moss-species-as-biomonitors-in-downwind-area-of-lead-zinc-mine
#10
Biljana Balabanova, Trajče Stafilov, Robert Šajn, Katerina Bačeva Andonovska
Distributions of a total of 21 elements were monitored in significantly lead-zinc polluted area using moss species (Hypnum cupressiforme and Camptothecium lutescens) used interchangeably, covering a denser sampling network. Interspecies comparison was conducted using Box-Cox transformed values, due to their skewed distribution. The median concentrations of trace elements in the both mosses examined decreased in the following order: Fe>Mn>Zn>Pb>Cu>Ni∼Cr∼As>Co>Cd>Hg. For almost all analyzed elements, H...
December 2, 2016: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/27909926/metals-as-chemical-tracers-to-discriminate-ecological-populations-of-threatened-franciscana-dolphins-pontoporia-blainvillei-from-argentina
#11
M B Romero, P Polizzi, L Chiodi, A Robles, K Das, M Gerpe
Franciscana dolphins are the most impacted small cetacean in the Southwestern Atlantic Ocean, classified as Vulnerable A3d by IUCN. Essential (Fe, Mo, Mn, Cr, Ni, Co) and non-essential (Ag, Pb, Sn) trace elements (TEs) were measured in liver, kidney, and brain samples of by-catch Franciscana dolphins that were living in estuarine (n = 21) and marine (n = 21) habitats (1) to assess whether TEs posed a threat and (2) to evaluate the suitability of TEs for discriminating ecological populations of this species in Argentinean waters...
December 1, 2016: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/27909395/reversal-learning-in-humans-and-gerbils-dynamic-control-network-facilitates-learning
#12
Christian Jarvers, Tobias Brosch, André Brechmann, Marie L Woldeit, Andreas L Schulz, Frank W Ohl, Marcel Lommerzheim, Heiko Neumann
Biologically plausible modeling of behavioral reinforcement learning tasks has seen great improvements over the past decades. Less work has been dedicated to tasks involving contingency reversals, i.e., tasks in which the original behavioral goal is reversed one or multiple times. The ability to adjust to such reversals is a key element of behavioral flexibility. Here, we investigate the neural mechanisms underlying contingency-reversal tasks. We first conduct experiments with humans and gerbils to demonstrate memory effects, including multiple reversals in which subjects (humans and animals) show a faster learning rate when a previously learned contingency re-appears...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27908430/evaluation-of-tissue-metal-and-trace-element-content-in-a-rat-model-of-non-alcoholic-fatty-liver-disease-using-icp-drc-ms
#13
Eugenia R Gatiatulina, Elizaveta V Popova, Valentina S Polyakova, Anastasia A Skalnaya, Eduard F Agletdinov, Alexandr A Nikonorov, Anatoly V Skalny, Alexey A Tinkov
The primary objective of the study was to assess the level of metals and trace elements in liver, serum, and hair of rats with diet-induced non-alcoholic fatty liver disease (NAFLD) using inductively coupled plasma dynamic reaction cell mass spectrometer (ICP-DRC-MS). 56 female 3-months-old Wistar rats divided into two equal groups were fed either standard (10% calories from fat) or high-fat high-carbohydrate diet (60% calories from fat in chow and 10% sucrose solution) for 6 weeks. Serum was examined for insulin resistance markers, lipid profile, and alanine aminotransferase (ALT) activity...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908428/contribution-of-mammalian-selenocysteine-containing-proteins-to-carcinogenesis
#14
REVIEW
Elena Gennadyevna Varlamova, Irina Valentinovna Cheremushkina
Oxidative stress caused by a sharp growth of free radicals in the organism is a major cause underlying the occurrence of all kinds of malignant formations. Selenium is an important essential trace element found in selenoproteins in the form of selenocysteine, an amino acid differing from cysteine for the presence of selenium instead of sulfur and making such proteins highly active. To date the role of selenium has been extensively investigated through studying the functions of selenoproteins in carcinogenesis...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908426/environmental-exposures-of-trace-elements-assessed-using-keratinized-matrices-from-patients-with-chronic-kidney-diseases-of-uncertain-etiology-ckdu-in-sri-lanka
#15
Saranga Diyabalanage, Sanjeewani Fonseka, D M S N B Dasanayake, Rohana Chandrajith
An alarming increase in chronic kidney disease with unknown etiology (CKDu) has recently been reported in several provinces in Sri Lanka and chronic exposures to toxic trace elements were blamed for the etiology of this disease. Keratinized matrices such as hair and nails were investigated to determine the possible link between CKDu and toxic element exposures. Elements Li, B, Al, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Sr, Mo, Cd, Ba, Hg and Pb of hair and nails of patients and age that matched healthy controls were determined with Inductively Coupled Plasma Mass Spectrometry (ICP-MS)...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908421/low-magnesium-diet-alters-distribution-of-macroelements-and-trace-elements-in-tissues-and-organs-of-female-rats
#16
Anastasia A Zheltova, Maria V Kharitonova, Igor N Iezhitsa, Eugeny P Serebryansky, Oleg Y Evsyukov, Alexander A Spasov, Anatoly V Skalny
The aim of the present study was to assess whether dietary magnesium deficiency can alter distribution of macroelements and trace elements in different organs and tissues. Experiments were carried out on 12 adult female Wistar rats, which were fed either a diet with low Mg content (≤20mgkg(-1) of diet) (LMgD) or a diet with daily recommended Mg content (≈500mgkg(-1)) as control group (CG) for 70 days. On the 70th day of the experiment heart, aorta, femoral skeletal muscle, forebrain, cerebellum, pituitary gland, thyroid gland, ovaries, uterus, liver, kidneys, and spleen were taken for analysis of mineral content...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908413/trace-element-and-cytokine-concentrations-in-patients-with-fibrodysplasia-ossificans-progressiva-fop-a-case-control-study
#17
Laura Hildebrand, Timo Gaber, Peter Kühnen, Rolf Morhart, Heinz Unterbörsch, Lutz Schomburg, Petra Seemann
Fibrodysplasia Ossificans Progressiva (FOP) is a rare inherited disease characterized by progressive heterotopic ossification. Disease onset, severity and symptoms vary between FOP patients, as does the frequency and activity of so-called flare-ups, during which tendons, ligaments, muscle and soft tissue are replaced by bone. Traumata, infections or other stressors are known inducers of flare-ups, and the hormone Activin A may be involved in disease activity; however, reliable biomarkers for FOP activity are missing, and the basal trace element and inflammatory state of patients are unknown...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908410/elevated-serum-mda-and-depleted-non-enzymatic-antioxidants-macro-minerals-and-trace-elements-are-associated-with-bipolar-disorder
#18
Manjurul Islam Chowdhury, Maimuna Hasan, Mohammad Safiqul Islam, Md Shahid Sarwar, Mohammad Nurul Amin, S M Naim Uddin, Md Zahedur Rahaman, Sujan Banik, Md Saddam Hussain, Kazushige Yokota, Abul Hasnat
Genetic and neurobiological factors are considered to be the major causes of mood and mental disorders. However, over the past few years, increased levels of serum malondialdehyde and altered levels of various non-enzymatic antioxidants and essential minerals involved in abnormal functional activity have been identified as major contributing factors to the pathogenesis of several neurological disorders. The aim of this study was to determine the levels of the serum lipid peroxidation product malondialdehyde (MDA), antioxidants (vitamin A, E and C), macro-minerals (calcium, potassium and sodium) and trace elements (zinc, iron and selenium) in patients with bipolar disorder and to explore their role in disease progression...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908408/protective-effect-of-magnesium-acetyltaurate-against-nmda-induced-retinal-damage-involves-restoration-of-minerals-and-trace-elements-homeostasis
#19
Azliana Jusnida Ahmad Jafri, Natasha Najwa Nor Arfuzir, Lidawani Lambuk, Igor Iezhitsa, Renu Agarwal, Puneet Agarwal, Norhafiza Razali, Anna Krasilnikova, Maria Kharitonova, Vasily Demidov, Evgeny Serebryansky, Anatoly Skalny, Alexander Spasov, Ahmad Pauzi Md Yusof, Nafeeza Mohd Ismail
Glutamate-mediated excitotoxicity involving N-methyl-d-aspartate (NMDA) receptors has been recognized as a final common outcome in pathological conditions involving death of retinal ganglion cells (RGCs). Overstimulation of NMDA receptors results in influx of calcium (Ca) and sodium (Na) ions and efflux of potassium (K). NMDA receptors are blocked by magnesium (Mg). Such changes due to NMDA overstimulation are also associated with not only the altered levels of minerals but also that of trace elements and redox status...
January 2017: Journal of Trace Elements in Medicine and Biology
https://www.readbyqxmd.com/read/27908407/effects-of-fluoride-on-insulin-signaling-and-bone-metabolism-in-ovariectomized-rats
#20
Amanda Gomes Pereira, Fernando Yamamoto Chiba, Maria Sara de Lima Coutinho Mattera, Renato Felipe Pereira, Rita de Cássia Alves Nunes, Thaís Verônica Saori Tsosura, Roberta Okamoto, Doris Hissako Sumida
Fluoride is an essential trace element for the maintenance of bone health owing to its capacity to stimulate proliferation and osteoblastic activity that can lead to increased bone formation. However, excessive sodium fluoride (NaF) intake can impair carbohydrate metabolism thereby promoting hyperglycemia, insulin resistance, and changes in insulin signaling. Thus, this study aimed to evaluate the effect of chronic treatment with NaF in bone metabolism, insulin signaling, and plasma concentrations of glucose, insulin, tumor necrosis factor-α (TNF-α), osteocalcin (OCN), and fluoride in ovariectomized rats...
January 2017: Journal of Trace Elements in Medicine and Biology
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