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Micronutrients

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https://www.readbyqxmd.com/read/28636149/photocatalytic-interaction-of-aminophylline-riboflavin-leads-to-ros-mediated-dna-damage-and-cell-death-a-novel-phototherapeutic-mechanism-for-cancer
#1
Saniyya Khan, Imrana Naseem
The accompanied tissue devastation and systemic toxicity of chemotherapy has shifted the quest for having an effective and palliative cancer therapy towards photodynamic therapy (PDT). Riboflavin (Rf), an essential micronutrient is emerging as a potent tool of PDT, due to its excellent photosensitizing properties. It can be used as an efficient adjuvant for various anticancer drugs. The hemolytic and proteolytic effect of photoilluminated aminophylline (Am), a xanthine derivative, and Rf is well documented in literature...
June 21, 2017: IUBMB Life
https://www.readbyqxmd.com/read/28635522/dietary-intake-among-opioid-and-alcohol-using-pregnant-women
#2
Shikhar Shrestha, Elizabeth Jimenez, Laura Garrison, Peter Pribis, Dennis W Raisch, Julia M Stephen, Ludmila N Bakhireva
BACKGROUND: Substance abuse in nonpregnant adults has been associated with increased intake in calories and decreased intake of nutrient-dense foods; however, studies examining dietary intake in opioid-using and alcohol-using pregnant women are lacking. OBJECTIVE: The objective of this study was to evaluate dietary intake in opioid-using pregnant women with or without concurrent light-to-moderate alcohol use as compared to abstaining controls. METHODS: This prospective birth cohort included 102 pregnant women classified into four study groups: controls (n = 27), medication-assisted treatment (MAT; n = 26), alcohol (ALC; n = 22), and concurrent use of both substances (MAT + ALC; n = 27)...
February 22, 2017: Substance Use & Misuse
https://www.readbyqxmd.com/read/28634484/manipulation-of-metabolic-pathways-to-develop-vitamin-enriched-crops-for-human-health
#3
REVIEW
Ling Jiang, Weixuan Wang, Tong Lian, Chunyi Zhang
Vitamin deficiencies are major forms of micronutrient deficiencies, and are associated with huge economic losses as well as severe physical and intellectual damages to humans. Much evidence has demonstrated that biofortification plays an important role in combating vitamin deficiencies due to its economical and effective delivery of nutrients to populations in need. Biofortification enables food plants to be enriched with vitamins through conventional breeding and/or biotechnology. Here, we focus on the progress in the manipulation of the vitamin metabolism, an essential part of biofortification, by the genetic modification or by the marker-assisted selection to understand mechanisms underlying metabolic improvement in food plants...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28633955/the-microbiome-and-transfusion-in-cancer-patients
#4
REVIEW
Hadi Goubran, Jerard Seghatchian, Julia Radosevic, Gaafar Ragab, Thierry Burnouf
Our microbiota is determined by many variables including ABO blood groups. The microbiota is not only confined to the gut and skin but is also recoverable from blood of healthy donors. The microbiota shape our immune system through cross reactivity with antigens, the expression of direct molecular patterns, the release of cytokines, the effects on nutrients and micronutrients and even through an interplay with epigenetics. It is likely, therefore, that a donor's microbiota could alter the antigenicity of blood and its components and potentially contribute to transfusion-related immune modulation [TRIM]...
June 3, 2017: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/28633872/frozen-yogurt-and-ice-cream-were-less-healthy-than-yogurt-and-adding-toppings-reduced-their-nutrition-value-evidence-from-1999-2014-national-health-and-nutrition-examination-survey
#5
Ruopeng An, Ning Jiang
It was hypothesized that frozen yogurt and ice cream would be less healthy than yogurt. We examined daily energy and nutrient intake from yogurt, frozen yogurt, and ice cream among US adults. In-person 24-hour dietary recall data (n=6453) came from the 1999-2014 National Health and Nutrition Examination Survey. Regression analyses were performed to examine the differences in energy/nutrient intake from frozen yogurt and ice cream (with/without toppings) in comparison to yogurt. Approximately 5.3%, 0.9%, and 14...
June 2017: Nutrition Research
https://www.readbyqxmd.com/read/28633691/dietary-gap-assessment-an-approach-for-evaluating-whether-a-country-s-food-supply-can-support-healthy-diets-at-the-population-level
#6
Edye M Kuyper, Reina Engle-Stone, Joanne E Arsenault, Mary Arimond, Katherine P Adams, Kathryn G Dewey
OBJECTIVE: Dietary diversity, and in particular consumption of nutrient-rich foods including fruits, vegetables, nuts, beans and animal-source foods, is linked to greater nutrient adequacy. We developed a 'dietary gap assessment' to evaluate the degree to which a nation's food supply could support healthy diets at the population level. Design/Setting In the absence of global food-based dietary guidelines, we selected the Dietary Approaches to Stop Hypertension (DASH) diet as an example because there is evidence it prevents diet-related chronic disease and supports adequate micronutrient intakes...
June 21, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28631167/copper-and-ectopic-expression-of-the-arabidopsis-transport-protein-copt1-alter-iron-homeostasis-in-rice-oryza-sativa-l
#7
Amparo Andrés-Bordería, Fernando Andrés, Antoni Garcia-Molina, Ana Perea-García, Concha Domingo, Sergi Puig, Lola Peñarrubia
Copper deficiency and excess differentially affect iron homeostasis in rice and overexpression of the Arabidopsis high-affinity copper transporter COPT1 slightly increases endogenous iron concentration in rice grains. Higher plants have developed sophisticated mechanisms to efficiently acquire and use micronutrients such as copper and iron. However, the molecular mechanisms underlying the interaction between both metals remain poorly understood. In the present work, we study the effects produced on iron homeostasis by a wide range of copper concentrations in the growth media and by altered copper transport in Oryza sativa plants...
June 19, 2017: Plant Molecular Biology
https://www.readbyqxmd.com/read/28630695/newly-formulated-protein-quality-enhanced-extruded-sorghum-cowpea-corn-soya-sugar-and-oil-containing-fortified-blended-foods-lead-to-adequate-vitamin-a-and-iron-outcomes-and-improved-growth-compared-with-non-extruded-csb-in-rats
#8
Nicole M Delimont, Nicole M Fiorentino, Alexander B Opoku-Acheampong, Michael V Joseph, Qingbin Guo, Sajid Alavi, Brian L Lindshield
Corn and soyabean micronutrient-fortified-blended foods (FBF) are commonly used for food aid. Sorghum and cowpeas have been suggested as alternative commodities because they are drought tolerant, can be grown in many localities, and are not genetically modified. Change in formulation of blends may improve protein quality, vitamin A and Fe availability of FBF. The primary objective of this study was to compare protein efficiency, Fe and vitamin A availability of newly formulated extruded sorghum-, cowpea-, soya- and corn-based FBF, along with a current, non-extruded United States Agency for International Development (USAID) corn and soya blend FBF (CSB+)...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28630693/quality-of-food-frequency-questionnaire-validation-studies-in-the-dietary-assessment-of-children-aged-12-to-36-months-a-systematic-literature-review
#9
REVIEW
Amy Lovell, Rhodi Bulloch, Clare R Wall, Cameron C Grant
A child's diet is an important determinant of growth and development. Because of this, the accurate assessment of dietary intake in young children remains a challenge. A systematic search of studies validating FFQ methodologies in children 12 to 36 months of age was completed. English-language articles published until March 2016 were searched using three electronic databases (MEDLINE, EMBASE and CINAHL). Quality assessment of the identified studies was carried out using The Reduced Summary Score and EURopean micronutrient RECommendations Aligned (EURRECA) scoring system...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28629722/the-manganese-efflux-system-mnte-contributes-to-the-virulence-of-streptococcus-suis-serotype-2
#10
Jiali Xu, Chengkun Zheng, Manman Cao, Ting Zeng, Xigong Zhao, Guolin Shi, Huanchun Chen, Weicheng Bei
Manganese is an essential micronutrient to bacteria and plays an important role in bacterial physiology. However, an excess of manganese is extremely deleterious to the cell. The manganese efflux system is used to control intracellular manganese levels by some bacteria. In this study, we have identified a cation efflux family protein (MntE) that functions as a manganese export system in Streptococcus suis serotype 2. To investigate the role of mntE in S. suis 2, a mntE deletion mutant (ΔmntE) and the corresponding complementation strain (CΔmntE) were constructed...
June 16, 2017: Microbial Pathogenesis
https://www.readbyqxmd.com/read/28629485/characterisation-of-vitamin-and-mineral-supplement-users-differentiated-according-to-their-motives-for-using-supplements-results-of-the-german-national-nutrition-monitoring-nemonit
#11
Anne Frey, Ingrid Hoffmann, Thorsten Heuer
OBJECTIVE: To characterise German vitamin and mineral supplement users differentiated by their motives for supplement use. DESIGN: Data were obtained from the German National Nutrition Monitoring (2010/11) via two 24 h dietary recalls and a telephone interview. Motive-based subgroups of supplement users were identified by factor and cluster analysis. Sociodemographic, lifestyle, health and dietary characteristics and supplement use were examined. Differences were analysed using χ 2 tests, logistic and linear regression models...
June 20, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28629136/zinc-in-infection-and-inflammation
#12
REVIEW
Nour Zahi Gammoh, Lothar Rink
Micronutrient homeostasis is a key factor in maintaining a healthy immune system. Zinc is an essential micronutrient that is involved in the regulation of the innate and adaptive immune responses. The main cause of zinc deficiency is malnutrition. Zinc deficiency leads to cell-mediated immune dysfunctions among other manifestations. Consequently, such dysfunctions lead to a worse outcome in the response towards bacterial infection and sepsis. For instance, zinc is an essential component of the pathogen-eliminating signal transduction pathways leading to neutrophil extracellular traps (NET) formation, as well as inducing cell-mediated immunity over humoral immunity by regulating specific factors of differentiation...
June 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28628658/effects-of-obesogenic-diet-and-estradiol-on-dorsal-raphe-gene-expression-in-old-female-macaques
#13
Cynthia L Bethea, Kevin Mueller, Arubala P Reddy, Steven G Kohama, Henryk F Urbanski
The beneficial effects of bioidentical ovarian steroid hormone therapy (HT) during the perimenopause are gaining recognition. However, the positive effects of estrogen (E) plus or minus progesterone (P) administration to ovariectomized (Ovx) lab animals were recognized in multiple systems for years before clinical trials could adequately duplicate the results. Moreover, very large numbers of women are often needed to find statistically significant results in clinical trials of HT; and there are still opposing results being published, especially in neural and cardiovascular systems...
2017: PloS One
https://www.readbyqxmd.com/read/28628394/nutritional-routine-of-tae-kwon-do-athletes-prior-to-competition-what-is-the-impact-of-weight-control-practices
#14
Sousana K Papadopoulou, Vasiliki A Dalatsi, Spyridon K Methenitis, Konstantinos G Feidantsis, Ioannis G Pagkalos, Maria Hassapidou
OBJECTIVE: The purpose of the present study was to investigate and assess the common dietary and weight management strategies of Tae Kwon Do (TKD) athletes prior to national competitions, as well as to examine the relationships between these strategies and body weight reduction and sensation of physical condition. METHODS: Sixty (n = 60) TKD athletes, 23 women (19.4 ± 2.9 years) and 37 men (20.4 ± 3.6 years), with at least 12.1 ± 3.1 years of experience, participated in the present study...
June 19, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28627205/a-low-fermentable-oligo-di-mono-saccharides-and-polyols-fodmap-diet-is-a-balanced-therapy-for-fibromyalgia-with-nutritional-and-symptomatic-benefits
#15
Ana Paula Marum, Cátia Moreira, Pablo Tomas-Carus, Fernando Saraiva, Catarina Sousa Guerreiro
INTRODUCTION: Fibromyalgia is a chronic rheumatic disease producing widespread pain, associated to a major comorbidity -irritable bowel syndrome. Low FODMAPS diet (low fermentable oligo-di-mono-saccharides and polyols diet) has been effective in controlling irritable bowel syndrome symptoms. Overweight is an aggravating factor for fibromyalgia. We studied effects of low fermentable oligo-di-mono-saccharides and polyols diets on fibromyalgia symptoms and weight status. METHODS: A longitudinal study was performed on 38 fibromyalgia patients using a four-week, repeated assessment as follow: M1 = first assessments/presentation of individual low fermentable oligo-di-mono-saccharides and polyols diet; M2 = second assessments/reintroduction of FODMAPs; M3 = final assessments/nutritional counselling...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28627190/-relationships-between-umbilical-vein-and-mother-iron-status
#16
Afaf Mezdoud, Abdel-Nacer Agli, Hayet Oulamara
INTRODUCTION: Iron is an essential micronutrient in the growing fetus. OBJECTIVE: The purpose of this study is to find the possible correlations that may exist between maternal and fetal iron status and newborn weight. MATERIAL AND METHODS: The study included 97 mothers scheduled to give birth by elective caesarean section in the central maternity of Tébessa (east of Algeria) between January and August 2014. The blood collection was sampled from the antecubital vein of the mother and the umbilical vein...
June 5, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/28626899/consideration-of-the-presence-of-inflammation-is-essential-for-interpretation-of-serum-micronutrient-results
#17
Emma Osland
It was with great interest I read the recent contribution by Christie-David and Gunton, 'Vitamin C deficiency and diabetes mellitus - easily missed?' [1], outlining their retrospective cohort study in 11 patients with poorly healing foot ulcers in the setting of diabetes mellitus. Their findings suggest previously unrecognized vitamin C deficiency may have been a contributing factor to the ulcers that were being treated in their clinic; a hypothesis supported by the healing reported to occur within 3 weeks of the commencement of vitamin C replacement [1]...
June 19, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28626279/nutritional-status-of-foster-children-in-the-u-s-implications-for-cognitive-and-behavioral-development
#18
Ursula A Tooley, Zeina Makhoul, Philip A Fisher
OBJECTIVE: Children in foster care are at greater risk for poor health, physical, cognitive, behavioral, and developmental outcomes than are children in the general population. Considerable research links early nutrition to later cognitive and behavioral outcomes. The aim of this narrative review is to examine the prevalence of poor nutrition and its relation to subsequent health and development in foster children. METHOD: Relevant studies for inclusion were identified from numerous sources (e...
November 2016: Children and Youth Services Review
https://www.readbyqxmd.com/read/28625202/development-and-evaluation-of-the-dutch-healthy-diet-index-2015
#19
Moniek Looman, Edith Jm Feskens, Mariëlle de Rijk, Saskia Meijboom, Sander Biesbroek, Elisabeth Hm Temme, Jeanne de Vries, Anouk Geelen
OBJECTIVE: To update the Dutch Healthy Diet index, a measure of diet quality, to reflect adherence to the Dutch dietary guidelines 2015 and to evaluate against participants' characteristics and nutrient intakes with the score based on 24 h recall (24 hR) data and FFQ data. DESIGN: The Dutch Healthy Diet index 2015 (DHD15-index) consists of fifteen components representing the fifteen food-based Dutch dietary guidelines of 2015. Per component the score ranges between 0 and 10, resulting in a total score between 0 (no adherence) and 150 (complete adherence)...
June 19, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28623904/impact-of-preconceptional-micronutrient-supplementation-on-maternal-mental-health-during-pregnancy-and-postpartum-results-from-a-randomized-controlled-trial-in-vietnam
#20
Phuong H Nguyen, Ann M DiGirolamo, Ines Gonzalez-Casanova, Hoa Pham, Wei Hao, Hieu Nguyen, Truong V Truong, Son Nguyen, Kimberly B Harding, Gregory A Reinhart, Reynaldo Martorell, Usha Ramakrishnan
BACKGROUND: Micronutrient malnutrition has been associated with maternal depressive symptoms (MDS), but little is known about the effects of preconceptional micronutrient supplementation. This paper examined the effects of preconceptional micronutrient supplementation on MDS during pregnancy and postpartum. METHODS: We used data from a double-blind controlled trial (PRECONCEPT) in which 5011 Vietnamese women were randomized to receive weekly supplements containing either a) multiple micronutrients (MM) b) iron and folic acid (IFA) or c) folic acid (FA) until conception (n = 1813)...
June 17, 2017: BMC Women's Health
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