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Fetal mri

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https://www.readbyqxmd.com/read/29468621/fusarium-brain-abscess-in-a-patient-with-diabetes-mellitus-and-liver-cirrhosis
#1
Yu-Ju Chen, Chao-Liang Chou, Kuan-Ju Lai, Ya-Ju Lin Lin
PURPOSE: Invasive mycosis caused by the Aspergillus, Fusarium, and Mucor can be fetal, especially in the immunocompromised patients with central nervous system (CNS) involvement. Here we present a case of CNS Fusarium infection, and this is the first reported case of Fusarium brain abscess in Taiwan. CASE REPORT: A 65-year-old woman presented with fever and conscious disturbance for 3 days. Neurological examination showed stupor consciousness, neck stiffness, multiple cranial nerves palsy, and bilateral Babinski signs...
September 15, 2017: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/29467359/evaluation-of-a-portable-doppler-ultrasound-gating-device-for-fetal-cardiac-mr-imaging-initial-results-at-1-5t-and-3t
#2
Fabian Kording, Bjoern P Schoennagel, Manuela Tavares de Sousa, Kai Fehrs, Gerhard Adam, Jin Yamamura, Christian Ruprecht
PURPOSE: Fetal cardiac MRI has the potential to play an important role in the assessment of fetal cardiac pathologies, but it is up to now not feasible due to a missing gating method. The purpose of this work was the evaluation of Doppler ultrasound (DUS) for external fetal cardiac gating with regard to compatibility, functionality, and reliability. Preliminary results were assessed performing fetal cardiac MRI. METHODS: An MRI conditional DUS device was developed to obtain a gating signal from the fetal heart...
February 21, 2018: Magnetic Resonance in Medical Sciences: MRMS
https://www.readbyqxmd.com/read/29465714/preeclampsia-induced-by-storkhead-box-1-overexpression-in-mice-induces-intrauterine-growth-restriction-abnormal-ultrasonography-and-blood-oxygenation-level-dependent-mri-signatures
#3
Hélène Collinot, Carmen Marchiol, Isabelle Lagoutte, Franck Lager, Nathalie Siauve, Gwennhael Autret, Daniel Balvay, Gilles Renault, Laurent J Salomon, Daniel Vaiman
BACKGROUND: Preeclampsia is a major hypertensive disease caused by pregnancy, inducing proteinuria and increased blood pressure starting from the second half of pregnancy (early preeclampsia) or near the end of pregnancy (late preeclampsia). Pre-symptomatic diagnosis would allow for therapeutic interventions, such as with low-dose aspirin. Among non-invasive methods to explore organ physiology, Doppler ultrasonography (US) and functional blood oxygenation level-dependent (BOLD) MRI (which do not need radioactive contrast agents such as gadolinium) can be used in pregnant women...
February 20, 2018: Journal of Hypertension
https://www.readbyqxmd.com/read/29463154/evaluation-of-changes-in-biochemical-composition-of-fetal-brain-between-18th-and-40th-gestational-week-in-proton-magnetic-resonance-spectroscopy
#4
Andrzej Urbanik, Monika Cichocka, Justyna Kozub, Paulina Karcz, Izabela Herman-Sucharska
INTRODUCTION: The aim of this study is to determine the right1 H MRS spectra of the brain in fetuses of different age, and then to define what metabolic changes occur between 18th and 40th weeks of pregnancy. METHODS: 1 H MRS studies of 32 fetuses aged 18-40 gestational weeks were performed, in which the MRI excluded central nervous system malformations. The studied group included 11 fetuses aged 18-25 weeks (the second half of the second trimester), 14 fetuses aged 26-33 weeks (the first half of the third trimester), and seven fetuses aged 34-40 weeks (the second half of the third trimester)...
February 20, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29460382/an-algorithm-for-predicting-robin-sequence-from-fetal-mri
#5
Cory M Resnick, Tessa D Kooiman, Carly E Calabrese, David Zurakowski, Bonnie L Padwa, Maarten J Koudstaal, Judy A Estroff
BACKGROUND: Infants with Robin sequence (RS) may present with airway compromise at delivery. Prenatal diagnosis would improve preparation and postnatal care. The purpose of this study was to devise a predictive algorithm for RS based on fetal magnetic resonance imaging (MRI). METHODS: Retrospective case-control study including fetal MRIs from 2002-2017. Inclusion criteria were: (1) MRI of adequate quality, (2) live-born infant, and (3) postnatal evaluation. Subjects were grouped based on postnatal diagnosis: (1) RS (micrognathia, glossoptosis, airway obstruction), (2) micrognathia without airway obstruction ("micrognathia"), (3) cleft lip and palate ("CLP"), and (4) gestational-age-matched controls...
February 19, 2018: Prenatal Diagnosis
https://www.readbyqxmd.com/read/29458892/prenatal-diagnosis-of-tuberous-sclerosis-complex-using-fetal-ultrasonography-and-magnetic-resonance-imaging-and-genetic-testing
#6
Chiu-Chi Wang, Chen-Yu Wang, Yu-Ju Lai, Tung-Yao Chang, Her-Young Su
No abstract text is available yet for this article.
February 2018: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29448602/preparation-of-silica-coated-magnetic-nanoparticles-for-bioseparation
#7
Dae-Won Lee, Hira Fatima, Kyo-Seon Kim
Magnetic nanoparticles have been intensively developed and applied in several biomedical applications such as targeted delivery, drug therapy, hyperthermia, magnetic resonance imaging and bioseparation etc. This work describes a simple and convenient method to synthesize silica coated Fe3O4 nanoparticles which have the potential to be used in the bioseparation of fetuin from fetal bovine serum and albumin from the egg. In this work, uniform Fe3O4 particles were prepared through the one-pot solvothermal process at 200 °C for 12 h using a sole iron precursor (FeCl3 · 6H2O) and then were coated with SiO2 to prepare silica coated Fe3O4 nanoparticles by hydrolysis and condensation of tetraethyl orthosilicate in ethanol and H2O medium...
February 1, 2018: Journal of Nanoscience and Nanotechnology
https://www.readbyqxmd.com/read/29447203/quantification-of-fetal-organ-volume-and-fat-deposition-following-in-utero-exposure-to-maternal-western-diet-using-mri
#8
Kevin J Sinclair, Lanette J Friesen-Waldner, Colin M McCurdy, Curtis N Wiens, Trevor P Wade, Barbra de Vrijer, Timothy R H Regnault, Charles A McKenzie
PURPOSE: To examine the feasibility of using MRI to identify differences in liver size and fat deposition in fetal guinea pigs exposed to an in utero environment influenced by maternal consumption of a Western diet. MATERIALS AND METHODS: Female guinea pigs fed either an energy-dense Western Diet (WD), comprised of increased saturated fats and simple sugars, or a Control Diet (CD) from weaning through pregnancy, underwent MR scanning near term (~ 60 days; term ~ 69 days)...
2018: PloS One
https://www.readbyqxmd.com/read/29444856/placental-physiology-monitored-by-hyperpolarized-dynamic-13-c-magnetic-resonance
#9
Stefan Markovic, Anne Fages, Tangi Roussel, Ron Hadas, Alexander Brandis, Michal Neeman, Lucio Frydman
Placental functions, including transport and metabolism, play essential roles in pregnancy. This study assesses such processes in vivo , from a hyperpolarized MRI perspective. Hyperpolarized urea, bicarbonate, and pyruvate were administered to near-term pregnant rats, and all metabolites displayed distinctive behaviors. Little evidence of placental barrier crossing was observed for bicarbonate, at least within the timescales allowed by 13 C relaxation. By contrast, urea was observed to cross the placental barrier, with signatures visible from certain fetal organs including the liver...
February 14, 2018: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/29441430/prenatal-diagnosis-of-apert-syndrome-using-ultrasound-magnetic-resonance-imaging-and-three-dimensional-virtual-physical-models-three-case-series-and-literature-review
#10
Heron Werner, Pedro Castro, Pedro Daltro, Jorge Lopes, Gerson Ribeiro, Edward Araujo Júnior
OBJECTIVE: This aimed to describe the prenatal diagnosis of three cases of Apert syndrome using two-dimensional (2D) and three-dimensional (3D) ultrasound, magnetic resonance imaging (MRI), and 3D virtual/physical models. METHODS: We retrospectively analyzed three cases of Apert syndrome at our service. The prenatal diagnostic methods used were 2D ultrasound, 3D ultrasound in conventional and HDlive rendering modes, T2-weighted MRI sequences, and 3D virtual/physical models from MRI or 3D ultrasound scan data...
February 13, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29438595/effects-of-early-alcohol-exposure-on-functional-organization-and-microstructure-of-a-visual-tactile-integrative-circuit
#11
Shiyu Tang, Su Xu, Rao P Gullapalli, Alexandre E Medina
BACKGROUND: Children with fetal alcohol spectrum disorders (FASD) often have deficits associated with multisensory processing. Because ethanol disrupts activity-dependent neuronal plasticity, a process that is essential for refining connections during cortical development, we hypothesize that early alcohol exposure results in alterations in multisensory cortical networks, which could explain the multisensory processing deficits seen in FASD. Here, we use a gyrencephalic animal model to test the prediction that early alcohol exposure alters the functional connectivity and microstructural features of the rostral posterior parietal cortex (PPr), a visual-tactile integrative area...
February 13, 2018: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29434494/schizencephaly-and-porencephaly-due-to-fetal-intracranial-hemorrhage-a-report-of-two-cases
#12
Takashi Harada, Takashi Uegaki, Kazuya Arata, Takako Tsunetou, Fuminori Taniguchi, Tasuku Harada
Schizencephaly and porencephaly are extremely rare types of cortical dysplasia. Case 1: Prenatal magnetic resonance imaging (MRI) showed wide clefts in the frontal and parietal lobes bilaterally. On postnatal day 3, MRI T2-weighted images showed multiple hypointensities in the clefts and ventricular walls, suggestive of hemosiderosis secondary to intracranial hemorrhage. Case 2: Prenatal MRI showed bilateral cleft and cyst formation in the fetal cerebrum, as well as calcification and hemosiderosis indicative of past hemorrhage...
December 2017: Yonago Acta Medica
https://www.readbyqxmd.com/read/29422210/pathophysiology-of-placental-derived-fetal-growth-restriction
#13
REVIEW
Graham J Burton, Eric Jauniaux
Placental-related fetal growth restriction arises primarily due to deficient remodeling of the uterine spiral arteries supplying the placenta during early pregnancy. The resultant malperfusion induces cell stress within the placental tissues, leading to selective suppression of protein synthesis and reduced cell proliferation. These effects are compounded in more severe cases by increased infarction and fibrin deposition. Consequently, there is a reduction in villous volume and surface area for maternal-fetal exchange...
February 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29420606/multifunctional-nanoparticles-for-real-time-evaluation-of-toxicity-during-fetal-development
#14
Sean Sweeney, Andrea Adamcakova-Dodd, Peter S Thorne, Jose G Assouline
Increasing production of nanomaterials in industrial quantities has led to public health concerns regarding exposure, particularly among pregnant women and developing fetuses. Information regarding the barrier capacity of the placenta for various nanomaterials is limited due to challenges working with ex vivo human placentas or in vivo animal models. To facilitate real-time in vivo imaging of placental transport, we have developed a novel, multifunctional nanoparticle, based on a core of mesoporous silica nanoparticles (MSN), and functionalized for magnetic resonance imaging (MRI), ultrasound, and fluorescent microscopy...
2018: PloS One
https://www.readbyqxmd.com/read/29419953/-the-role-of-fetal-magnetic-resonance-imaging-in-the-study-of-congenital-diaphragmatic-hernia
#15
V Núñez, M Romo, J L Encinas, A Bueno, B Herrero, E Antolín, L Martínez, M López Santamaría
INTRODUCTION AND OBJECTIVES: Different echographic and fetal magnetic resonance (MRI) measurements have been described in the diagnosis of associated malformations and the prognosis of congenital diaphragmatic hernia (CDH). We have reviewed our experience searching for useful isolated or combined parameters and how MRI can complement ultrasound. MATERIAL AND METHODS: We evaluated 29 fetuses with CDH. We examined ultrasonography: Lung to Head (LHR o/e) and in MRI: ipsilateral lung volume (IPV) and total expressed as percentage of observed / expected lung volume (VPT o/e) and percentage of herniated liver (PHH)...
February 1, 2018: Cirugía Pediátrica: Organo Oficial de la Sociedad Española de Cirugía Pediátrica
https://www.readbyqxmd.com/read/29419693/organ-damage-mitigation-with-the-baskent-sickle-cell-medical-care-development-program-bascare
#16
Hakan Ozdogu, Can Boga, Suheyl Asma, Ilknur Kozanoglu, Cigdem Gereklioglu, Mahmut Yeral, Nurhilal Turgut Buyukkurt, Soner Solmaz, Aslı Korur, Pelin Aytan, Erkan Maytalman, Mutlu Kasar
The Eastern Mediterranean is among the regions where sickle cell disease (SCD) is common. The morbidity and mortality of this disease can be postponed to adulthood through therapies implemented in childhood. The present study focuses on the organ damage-reducing effects of the Baskent Sickle Cell Medical Care Development Program (BASCARE), which was developed by a team who lives in this region and has approximately 25 years of experience. The deliverables of the program included the development of an electronic health recording system (PRANA) and electronic vaccination system; the use of low citrate infusion in routine prophylactic automatic erythrocyte exchange (ARCE) programs including pregnant women; the use of leukocyte-filtered and irradiated blood for transfusion; the use of magnetic resonance imaging methods (T2) for the management of transfusion-related hemosiderosis; and the implementation of an allogeneic hematopoietic stem cell transplantation protocol for adult patients...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29410108/post-mortem-microfocus-computed-tomography-for-early-gestation-fetuses-a-validation-study-against-conventional-autopsy
#17
John C Hutchinson, Xin Kang, Susan Cheng Shelmerdine, Valerie Segers, Claudio M Lombardi, Mieke M Cannie, Neil J Sebire, Jacques C Jani, Owen J Arthurs
BACKGROUND: Perinatal autopsy provides useful clinical information in up to 40% of cases. However, there is a substantial unmet clinical need with regards to post mortem investigation of early gestation fetal loss for parents for whom standard autopsy is either not available or not acceptable. Parents dislike the invasive nature of autopsy, but current clinical imaging techniques do not provide high-enough imaging resolution in small fetuses. We hypothesized that microfocus computed tomography, a rapid, high resolution imaging technique, could give accurate diagnostic imaging following early gestation fetal loss...
January 31, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29408744/the-use-of-antenatal-fetal-magnetic-resonance-imaging-in-the-assessment-of-patients-at-high-risk-of-preterm-birth
#18
REVIEW
L Story, J Hutter, T Zhang, A H Shennan, M Rutherford
Preterm birth, defined as birth occurring prior to 37 weeks gestation is a common obstetric complication affecting 8% of pregnancies and is associated with significant morbidity and mortality. Infection/inflammation has been implicated in both the aetiology of preterm birth itself and associated neonatal pulmonary and neurological morbidity. Treatment options are currently limited to prolongation of the pregnancy using cervical cerclage, pessaries or progesterone or administration of drugs including steroids to promote lung maturity and neuroprotective agents such as magnesium sulphate, the timing of which are highly critical...
March 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29406268/therapeutic-n-acetyl-cysteine-nac-following-initiation-of-maternal-inflammation-attenuates-long-term-offspring-cerebral-injury-as-evident-in-magnetic-resonance-imaging-mri
#19
Hila Sharabi, Nizar Khatib, Yuval Ginsberg, Zeev Weiner, Michael G Ross, Blumenfeld-Katzir Tamar, Sasson Efrat, Hallak Mordechai, Ron Beloosesky
OBJECTIVE: Maternal infection/inflammation may induce fetal inflammatory responses, which have been associated with long-term offspring cerebral injury. We previously demonstrated that prophylactic N-Acetyl-Cysteine (NAC), administered prior to and following maternal lipopolysaccharide (LPS), reduced offspring cerebral injury as evident on MRI. In the present study, we used MRI to examine the effect of therapeutic NAC following maternal LPS-induced inflammation on neonatal brain injury...
February 1, 2018: Neuroscience
https://www.readbyqxmd.com/read/29405479/persistent-extreme-hyperextension-of-the-fetal-neck-clinical-and-neuroimaging-findings
#20
Shai Shrot, Clark T Johnson, W Christopher Golden, Ahmet A Baschat, Janine E Bullard, Aylin Tekes, Andrea Poretti, Emily Dunn, Thierry A G M Huisman
BACKGROUND AND PURPOSE: Persistent hyperextension of the fetal craniocervical junction or neck is one of several fetal positions commonly observed on prenatal imaging. Underlying fetal structural etiologies such as fetal neck masses and iniencephaly can be detected as causes of hyperextension. Caesarean delivery is considered in cases of vaginal delivery or obstructed labor for fear of cervical spinal cord injury. In this case series, we describe the prenatal magnetic resonance imaging (MRI) findings and their potential role in obstetric management and discuss postnatal outcomes in fetuses demonstrating prenatal imaging findings of persistent extreme hyperextension of the neck...
February 5, 2018: Journal of Neuroimaging: Official Journal of the American Society of Neuroimaging
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