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Fetal mri

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https://www.readbyqxmd.com/read/29674414/volumetric-brain-mri-study-in-fetuses-with-congenital-heart-disease
#1
H Olshaker, R Ber, D Hoffman, E Derazne, R Achiron, E Katorza
BACKGROUND AND PURPOSE: It is well-established that a high prevalence of infants with congenital heart defects surviving to childhood have neurodevelopmental abnormalities. The etiology is not clear. In this study, we aimed to find prenatal neuroanatomic changes in fetuses with congenital heart disease to better understand the pathophysiology behind these sequelae. MATERIALS AND METHODS: A retrospective study of 46 fetal brain MR imaging scans was performed at a tertiary medical center during a 4-year period...
April 19, 2018: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/29674194/resting-state-functional-connectivity-in-children-born-from-gestations-complicated-by-preeclampsia-a-pilot-study-cohort
#2
Lauren E Mak, B Anne Croy, Vanessa Kay, James N Reynolds, Matthew T Rätsep, Nils D Forkert, Graeme N Smith, Angelina Paolozza, Patrick W Stroman, Ernesto A Figueiró-Filho
BACKGROUND: Individuals (PE-F1s) born from preeclampsia (PE)-complicated pregnancies have elevated risks for cognitive impairment. Intervals of disturbed maternal plasma angiokines precede clinical signs of PE. We hypothesized pan-blastocyst dysregulation of angiokines underlies altered PE-F1 brain vascular and neurological development. This could alter brain functional connectivity (FC) patterns at rest. MATERIALS AND METHODS: Resting-state functional MRI datasets of ten, matched child pairs (5 boys and 5 girls aged 7-10 years of age) from PE or control pregnancies were available for study...
February 7, 2018: Pregnancy Hypertension
https://www.readbyqxmd.com/read/29670784/ultrasound-presentation-of-a-disseminated-fetal-and-neonatal-rhabdoid-tumor
#3
Yolaine Joueidi, Aline Rousselin, Céline Rozel, Philippe Loget, Dominique Ranchere Vince, Sylvie Odent, Franck Bourdeaut, Vincent Lavoue, Maela Le Lous
This is a case report of a disseminated fetal rhabdoid tumor discovered at 32 weeks of gestation in a 29-year-old woman on immunosuppressive therapy. The mother consulted for a decrease in fetal movement. Fetal ultrasound showed signs of a disseminated tumor affecting the left armpit, liver, spleen, and limbs. A caesarian section was performed because of signs of fetal distress. Immunohistochemical analysis of a fetal biopsy showed deletion of the SMARCB1 gene. Pathological analysis of the placenta showed a rhabdoid tumor invading both fetal and maternal compartments...
2018: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29656679/three-dimensional-reconstruction-of-fetal-abnormalities-using-ultrasonography-and-magnetic-resonance-imaging
#4
Heron Werner, Maene Marcondes, Pedro Daltro, Tatiana Fazecas, Bianca Guedes Ribeiro, Renata Nogueira, Edward Araujo Júnior
OBJECTIVE: We aimed to compare three-dimensional (3D) fetal malformation images obtained using ultrasonography (US) and magnetic resonance imaging (MRI) on the same day during the third trimester of pregnancy. METHODS: Total 33 fetuses were selected from cases evaluated for malformations. Morphological abnormalities were first scanned using 3DUS . MRI was used to confirm the previous preliminary 3DUS findings, and diagnoses were confirmed postnatally. 3DUS scans were performed transabdominally using an Rab (4-8 L) probe, Voluson 730 Pro/Expert and E8 (General Electric, Healthcare, Zipf, Austria)...
April 15, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29655938/delineation-of-early-brain-development-from-fetuses-to-infants-with-diffusion-mri-and-beyond
#5
REVIEW
Minhui Ouyang, Jessica Dubois, Qinlin Yu, Pratik Mukherjee, Hao Huang
Dynamic macrostructural and microstructural changes take place from the mid-fetal stage to 2 years after birth. Delineating brain structural changes during this early developmental period provides new insights into the complicated processes of both typical brain development and the pathological mechanisms underlying various psychiatric and neurological disorders including autism, attention deficit hyperactivity disorder and schizophrenia. Decades of histological studies have identified strong spatial and functional gradients of maturation in human brain gray and white matter...
April 12, 2018: NeuroImage
https://www.readbyqxmd.com/read/29649902/fetal-mr-imaging-in-urogenital-system-anomalies
#6
Armaghan Faghihimehr, Mohammad Gharavi, Melissa Mancuso, Gayathri Sreedher
Fetal magnetic resonance imaging (MRI) is an important adjunct to ultrasound in evaluation of fetal urogenital system. While, ultrasound remains the primary modality, MRI helps in more complicated cases or where ultrasound is limited due to technical factors such as poor acoustic window. The goal of this article is to review the common fetal urogenital anomalies and their imaging manifestations on ultrasound and MRI, and discuss how MRI adds diagnostic value.
April 12, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29643159/role-of-iodine-containing-multivitamins-during-pregnancy-for-children-s-brain-function-protocol-of-an-ongoing-randomised-controlled-trial-the-swiddich-study
#7
Sofia Manousou, Birgitta Johansson, Anna Chmielewska, Janna Eriksson, Kerstin Gutefeldt, Carl-Johan Tornhage, Robert Eggertsen, Helge Malmgren, Lena Hulthen, Magnus Domellöf, Helena Nystrom Filipsson
INTRODUCTION: Iodine is essential for normal brain development. Moderate and severe fetal iodine deficiency results in substantial to serious developmental delay in children. Mild iodine deficiency in pregnancy is associated with neurodevelopmental deficits in the offspring, but evidence from randomised trials is lacking. The aim of the Swedish Iodine in Pregnancy and Development in Children study is to determine the effect of daily supplementation with 150 µg iodine during pregnancy on the offspring's neuropsychological development up to 14 years of age...
April 10, 2018: BMJ Open
https://www.readbyqxmd.com/read/29623485/imaging-of-neurovascular-emergencies-in-pregnancy-and-puerperium
#8
Kajari Bhattacharya, Hima Pendharkar
Acute neurovascular events, though rare, can complicate pregnancy and postpartum period. It is important to be aware of these clinical conditions for reducing maternal and fetal morbidity and mortality. In this review, we present a few important neurovascular emergencies and their imaging manifestations by various imaging modalities-computed tomography (CT), magnetic resonance imaging (MRI), and digital subtraction angiography (DSA)-which presented at our institution in the peripartum period.
April 6, 2018: Emergency Radiology
https://www.readbyqxmd.com/read/29622396/the-distended-fetal-hypopharynx-a-sensitive-and-novel-sign-for-the-prenatal-diagnosis-of-esophageal-atresia
#9
Sarah Tracy, Terry L Buchmiller, Offir Ben-Ishay, Carol E Barnewolt, Susan A Connolly, David Zurakowski, Andrew Phelps, Judy A Estroff
BACKGROUND/PURPOSE: Although advances have been made in the prenatal diagnosis of esophageal atresia (EA), most neonates are not identified until after birth. The distended hypopharynx (DHP) has been suggested as a novel prenatal sign for EA. We assess its diagnostic accuracy and predictive value on ultrasound (US) and magnetic resonance imaging (MRI), both alone and in combination with the esophageal pouch (EP) and secondary signs of EA (polyhydramnios and a small or absent fetal stomach)...
March 7, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29618564/postnatal-zika-virus-infection-is-associated-with-persistent-abnormalities-in-brain-structure-function-and-behavior-in-infant-macaques
#10
Maud Mavigner, Jessica Raper, Zsofia Kovacs-Balint, Sanjeev Gumber, Justin T O'Neal, Siddhartha K Bhaumik, Xiaodong Zhang, Jakob Habib, Cameron Mattingly, Circe E McDonald, Victoria Avanzato, Mark W Burke, Diogo M Magnani, Varian K Bailey, David I Watkins, Thomas H Vanderford, Damien Fair, Eric Earl, Eric Feczko, Martin Styner, Sherrie M Jean, Joyce K Cohen, Guido Silvestri, R Paul Johnson, David H O'Connor, Jens Wrammert, Mehul S Suthar, Mar M Sanchez, Maria C Alvarado, Ann Chahroudi
The Zika virus (ZIKV) epidemic is associated with fetal brain lesions and other serious birth defects classified as congenital ZIKV syndrome. Postnatal ZIKV infection in infants and children has been reported; however, data on brain anatomy, function, and behavioral outcomes following infection are absent. We show that postnatal ZIKV infection of infant rhesus macaques (RMs) results in persistent structural and functional alterations of the central nervous system compared to age-matched controls. We demonstrate ZIKV lymphoid tropism and neurotropism in infant RMs and histopathologic abnormalities in the peripheral and central nervous systems including inflammatory infiltrates, astrogliosis, and Wallerian degeneration...
April 4, 2018: Science Translational Medicine
https://www.readbyqxmd.com/read/29608113/3d-virtual-broncoscopy-before-feto-procedure-in-a-fetus-with-severe-isolated-left-congenital-diaphragmatic-hernia
#11
Gabriele Tonni, Rodrigo Ruano, Renato Sà, Fernando Maia Peixoto Filho, Jorge Lopes, Heron Werner
INTRODUCTION: Congenital diaphragmatic hernia (CDH) is a life-threatening event in severe forms and fetuses affected may benefit from in utero treatment by fetoscopic endotracheal occlusion (FETO). MATERIALS AND METHODS: Application of 3D virtual bronchoscopy in a case of severe, isolated, left CDH before performing FETO procedure at 27 week's gestation is reported. RESULTS: The 3D virtual imaging of the fetal trachea was technically useful in planning the real FETO procedure...
April 2, 2018: Fetal and Pediatric Pathology
https://www.readbyqxmd.com/read/29607569/neurodevelopmental-outcome-of-fetal-isolated-ventricular-asymmetry-without-dilation-a-cohort-study
#12
Raanan Meyer, Omer Bar-Yosef, Eran Barzilay, Dana Hoffman, Shlomi Toussia-Cohen, Elad Zvi, Reuven Achiron, Eldad Katorza
OBJECTIVE: Fetal isolated ventricular asymmetry (IVA) is a relatively common finding in pregnancy, but data regarding its effect on neurodevelopmental outcome is scarce and principally founded on ultrasound-based studies. The purpose of this study was to assess the outcome of such cases in a magnetic resonance imaging based study. METHODS: Cases referred to fetal brain MR imaging as part of the investigation of IVA without ventriculomegaly (≤10 mm), identified during routine ultrasound examinations, were assessed for possible inclusion...
April 1, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29606355/fetal-neuropathology-in-zika-virus-infected-pregnant-female-rhesus-monkeys
#13
Amanda J Martinot, Peter Abbink, Onur Afacan, Anna K Prohl, Roderick Bronson, Jonathan L Hecht, Erica N Borducchi, Rafael A Larocca, Rebecca L Peterson, William Rinaldi, Melissa Ferguson, Peter J Didier, Deborah Weiss, Mark G Lewis, Rafael A De La Barrera, Edward Yang, Simon K Warfield, Dan H Barouch
The development of interventions to prevent congenital Zika syndrome (CZS) has been limited by the lack of an established nonhuman primate model. Here we show that infection of female rhesus monkeys early in pregnancy with Zika virus (ZIKV) recapitulates many features of CZS in humans. We infected 9 pregnant monkeys with ZIKV, 6 early in pregnancy (weeks 6-7 of gestation) and 3 later in pregnancy (weeks 12-14 of gestation), and compared findings with uninfected controls. 100% (6 of 6) of monkeys infected early in pregnancy exhibited prolonged maternal viremia and fetal neuropathology, including fetal loss, smaller brain size, and histopathologic brain lesions, including microcalcifications, hemorrhage, necrosis, vasculitis, gliosis, and apoptosis of neuroprogenitor cells...
March 28, 2018: Cell
https://www.readbyqxmd.com/read/29594083/large-parotid-gland-lipoblastoma-in-a-teenager
#14
Danny Jandali, Ashley Heilingoetter, Ritu Ghai, Jill Jeffe, Samer Al-Khudari
Background: Lipoblastomas are rare benign neoplasms that arise from fetal white fat cells. They are typically found in children under the age of 3 and have been reported in the mediastinum, extremities, and infrequently in the head and neck. We present a rare case of a lipoblastoma arising from the parotid gland and the first known report of a parotid lipoblastoma in a teenager. Case presentation: A 15-year-old male presented with a painless, slowly enlarging parotid mass and left facial swelling...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29580786/neurodevelopmental-outcomes-in-cdh-survivors-a-single-institution-s-experience
#15
Joseph T Church, Rodrigo Mon, Tiffany Wright, Megan A Coughlin, Maria Ladino-Torres, Christopher Tapley, Heather Bowen, Niki Matusko, George B Mychaliska
PURPOSE: Survivors of congenital diaphragmatic hernia (CDH) face high morbidity. We studied the neurodevelopmental outcomes of CDH survivors at a single institution. METHODS: CDH survivors born July 2006-March 2016 at a free-standing children's hospital were reviewed. Neurodevelopment was assessed using the Peabody Developmental Motor Scales (PDMS-2) broken into gross, fine, and total motor quotients. Data collected included prenatal variables (liver herniation, defect laterality, observed:expected total fetal lung volume (o:eTFLV) on MRI), birth demographics (sex, race, estimated gestational age (EGA), birth weight (BtWt), 5 min APGAR, associated anomalies), and therapies/hospital course (HFOV/HFJV, ECMO, timing of repair, pulmonary hypertension (PHTN) severity, length of stay, ventilator days)...
March 5, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29580171/mri-for-fetal-developmental-brain-abnormalities-perspectives-from-the-pregnant-patient
#16
Mabel L S Lie, Ruth H Graham, Stephen C Robson, Paul D Griffiths
Ultrasound is routinely used as a prenatal screening and diagnostic tool but has limitations. Some anomalies in the developing fetal brain can be difficult to detect, and in utero magnetic resonance imaging (iuMRI) is increasingly used as an adjunct to ultrasound. However, understandings of patient perspectives of iuMRI technology are still developing. Our qualitative study of 41 mothers who experienced iuMRI was embedded in a diagnostic accuracy trial and aimed to inform policy recommendations that might stem from the clinical findings...
March 1, 2018: Qualitative Health Research
https://www.readbyqxmd.com/read/29570256/laparoscopic-management-of-paraganglioma-in-a-pregnant-woman-a-case-report
#17
Mohammad Hadi Radfar, Behnam Shakiba, Amir Afyouni, Hassan Hoshyar
INTRODUCTION: Paraganglioma is an extremely rare catecholamine-producing tumor during pregnancy. Paraganglioma carries high risks of fetal and maternal mortality during pregnancy. We report a pregnant woman with paraganglioma in the second trimester. CASE DESCRIPTION: A 24-year-old pregnant woman presented with severe hypertension in the 17th week of gestation. Hormonal examination and Magnetic Resonance Imaging (MRI) confirmed the diagnosis of extra adrenal pheochromocytoma (paraganglioma)...
March 23, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29554458/in-utero-glossoptosis-in-fetuses-with-robin-sequence-measurements-from-prenatal-mri
#18
Cory M Resnick, Tessa D Kooiman, Carly E Calabrese, Ryne Didier, Bonnie L Padwa, Judy A Estroff, Maarten J Koudstaal
OBJECTIVE: Glossoptosis causes airway obstruction in patients with Robin sequence (RS), but little is known about the in-utero tongue. The purpose of this study was to assess shape and position of the fetal tongue on prenatal magnetic resonance imaging (MRI) to determine if this is predictive of postnatal RS. DESIGN: Retrospective case-control study including fetuses with prenatal MRIs performed from 2002 to 2017. Inclusion criteria were (1) prenatal MRI of adequate quality, (2) live born and evaluated postnatally for craniofacial findings...
April 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29550866/fetal-anterior-abdominal-wall-defects-prenatal-imaging-by-magnetic-resonance-imaging
#19
REVIEW
Teresa Victoria, Savvas Andronikou, Diana Bowen, Pablo Laje, Dana A Weiss, Ann M Johnson, William H Peranteau, Douglas A Canning, N Scott Adzick
Abdominal wall defects range from the mild umbilical cord hernia to the highly complex limb-body wall syndrome. The most common defects are gastroschisis and omphalocele, and the rarer ones include the exstrophy complex, pentalogy of Cantrell and limb-body wall syndrome. Although all have a common feature of viscera herniation through a defect in the anterior body wall, their imaging features and, more important, postnatal management, differ widely. Correct diagnosis of each entity is imperative in order to achieve appropriate and accurate prenatal counseling and postnatal management...
April 2018: Pediatric Radiology
https://www.readbyqxmd.com/read/29550864/fetal-neuroimaging-an-update-on-technical-advances-and-clinical-findings
#20
REVIEW
Ashley J Robinson, M Ashraf Ederies
This paper is based on a literature review from 2011 to 2016. The paper is divided into two main sections. The first section relates to technical advances in fetal imaging techniques, including fetal motion compensation, imaging at 3.0 T, 3-D T2-weighted MRI, susceptibility-weighted imaging, computed tomography, morphometric analysis, diffusion tensor imaging, spectroscopy and fetal behavioral assessment. The second section relates to clinical updates, including cerebral lamination, migrational anomalies, midline anomalies, neural tube defects, posterior fossa anomalies, sulcation/gyration and hypoxic-ischemic insults...
April 2018: Pediatric Radiology
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