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Jonathan S Howard, Cherilyn N McLester, Thomas W Evans, John R McLester, Jimmy P Calloway
The PhysioFlow™ is a piece of equipment that uses bioimpedance cardiography to measure central hemodynamics. The purpose of this research was to explore the novel approach of monitoring central hemodynamics during free weight resistance exercise using bioimpedance cardiography throughout a 5 repetition maximum (5RM). Thirty participants ranging from beginner to advanced lifters (16 males and 14 females) completed a 5RM for back squat, seated push press, and bicep curl while connected to the PhysioFlow™ to assess the response of heart rate (HR), stroke volume (SV), cardiac output (Q), and ejection fraction (EF)...
2018: International Journal of Exercise Science
Marion Dupuis, Elise Noel-Savina, Gregoire Prévot, Laurent Tétu, Fabien Pillard, Daniel Rivière, Alain Didier
BACKGROUND: Cardiac output (CO) is a prognostic factor in pulmonary hypertension (PH). Right heart catheterisation using the direct Fick method or thermodilution (TD) is the reference technique for CO measurement. Impedance cardiography (IPc) is a known non-invasive method of measuring CO. OBJECTIVES: In our study, we assume that the measurement of CO by IPc using the PHYSIOFLOW® system is as accurate as TD or using the direct Fick method in patients with PH in group 1 or group 4...
February 9, 2018: Respiration; International Review of Thoracic Diseases
Antoine Legendre, D Bonnet, L Bosquet
Global ventricular response to exercise may be useful in follow-up of patients with residual right outflow tract lesions after congenital heart disease repair. In this context, impedance cardiography is considered accurate for stroke volume (SV) measurement during exercise testing, however, to date, only partial assessment of its reliability has been reported. We retrospectively evaluated relative and absolute reliability of peak SV by impedance cardiography during exercise using intraclass correlation (ICC) and standard error of measurement (SEM) in this population...
January 2018: Pediatric Cardiology
Pawel Niedzwiecki, Dariusz Naskret, Stanislaw Pilacinski, Maciej Pempera, Aleksandra Uruska, Anna Adamska, Dorota Zozulinska-Ziolkiewicz
BACKGROUND: The aim of this study was to assess the hemodynamic parameters analyzed in bioimpedance cardiography during maximal exercise in patients with type 1 diabetes differing in insulin resistance. METHODS: The study group consisted of 40 men with type 1 diabetes. Tissue sensitivity to insulin was assessed on the basis of the glucose disposal rate (GDR) analyzed during hyperinsulinemic-euglycemic clamp. Patients were divided into groups with GDR <4.5 mg/kg/min (G1 group-lower insulin sensitivity) and GDR ≥4...
June 2017: Metabolic Syndrome and related Disorders
Marios Panagiotou, Ioannis Vogiatzis, Geeshath Jayasekera, Zafeiris Louvaris, Alison Mackenzie, Neil Mcglinchey, Julien S Baker, Alistair C Church, Andrew J Peacock, Martin K Johnson
BACKGROUND: Non-invasive methods of measuring cardiac output are highly desirable in pulmonary arterial hypertension (PAH). We therefore sought to validate impedance cardiography (ICG) against thermodilution (TD) and cardiac magnetic resonance (CMR) in the measurement of cardiac output in patients under investigation for PAH. METHODS: A prospective, cross-sectional study was performed to compare single-point measurements of cardiac output obtained by impedance cardiography (COICG ) technology (PhysioFlow® ) with (i) contemporaneous TD measurements (COTD ) at rest and steady-state exercise during right heart catheterization and (ii) CMR measurements (COCMR ) at rest obtained within 72 h...
March 2018: Clinical Physiology and Functional Imaging
Antoine Legendre, Aurore Guillot, Magalie Ladouceur, Damien Bonnet
BACKGROUND: Aerobic capacity (VO2 max) of patients with Fontan circulation (FC) is lowest within patients with congenital heart disease. The reasons have not been completely elucidated. METHODS: Twenty five young patients with non-failing FC underwent a cardiopulmonary test during an upright ramp cycling. By using a signal morphology impedance cardiography device (physioflow®), stroke volume (SV) was evaluated along with effort. The results were compared with paired healthy controls...
January 15, 2017: International Journal of Cardiology
Jason D Payseur, John J Rigney, Sandra L Turner, XueJun Wu, Dennis J Murphy, Eric I Rossman
INTRODUCTION: Currently, standard methods for measuring cardiac output are either invasive (i.e. flow probe) or are limited in terms of short measurement intervals and measurement variability (i.e. echocardiography). The ability to reliably measure cardiac output in a non-invasive manner in large animals would provide a valuable tool to expand functional cardiovascular endpoints in preclinical safety studies. PhysioFlow® is a novel method that uses waveform analysis of an impedance signal to measure cardiac output non-invasively...
September 2016: Journal of Pharmacological and Toxicological Methods
I Nasis, E Kortianou, Μ Vasilopoulou, S Spetsioti, Z Louvaris, G Kaltsakas, C H Davos, S Zakynthinos, N G Koulouris, I Vogiatzis
Dynamic hyperinflation (DH) has a significant adverse effect on cardiovascular function during exercise in COPD patients. COPD patients with (n = 25) and without (n = 11) exercise-induced DH undertook an incremental (IET) and a constant-load exercise test (CLET) sustained at 75% peak work (WRpeak) prior to and following an interval cycling exercise training regime (set at 100% WRpeak with 30-s work/30-s rest intervals) lasting for 12 weeks. Cardiac output (Q) was assessed by cardio-bio-impedance (PhysioFlow, enduro, PF-O7) to determine Q mean response time (QMRT) at onset (QMRT(ON)) and offset (QMRT(OFF)) of CLET...
October 2015: Respiratory Physiology & Neurobiology
A Stalter, N Lanot, G Bridon, V Julian, B Péreira, R Richard
OBJECTIVES: EsCCO is a novel non-invasive continuous cardiac output monitoring system based on pulse wave transit time already validated at rest. The aim of our study was to compare cardiac output measurements obtained simultaneously by EsCCO(®) (Q˙cOP) and impedance cardiography (Physioflow(®) ; Q˙cIMP), in healthy subjects. PATIENTS AND METHODS: Eight healthy subjects (age: 31±9 years, weight: 76±10kg, height: 179±5cm) realized two exercise tests: an incremental ergocycle test performed until exertion (Pmax=269±48W) and a constant load exercise (P=163±27W)...
February 2016: Annales de Cardiologie et D'angéiologie
Adriano R Tonelli, Xiao-Feng Wang, Laith Alkukhun, Qi Zhang, Raed A Dweik, Omar A Minai
Six-minute walk test (6MWT) continues to be a useful tool to determine the functional capacity in patients with vascular and other lung diseases; nevertheless, it has a limited ability to predict prognosis in this context. We tested whether the heart rate (HR) acceleration and decay slopes during the 6-m walk test are different in patients with pulmonary arterial hypertension (PAH), other lung diseases, and healthy controls. In addition, we assessed whether the HR slopes are associated with clinical worsening...
June 1, 2014: Physiological Reports
C Siebenmann, P Rasmussen, H Sørensen, M Zaar, M Hvidtfeldt, A Pichon, N H Secher, C Lundby
Several techniques assessing cardiac output (Q) during exercise are available. The extent to which the measurements obtained from each respective technique compares to one another, however, is unclear. We quantified Q simultaneously using four methods: the Fick method with blood obtained from the right atrium (Q(Fick-M)), Innocor (inert gas rebreathing; Q(Inn)), Physioflow (impedance cardiography; Q(Phys)), and Nexfin (pulse contour analysis; Q(Pulse)) in 12 male subjects during incremental cycling exercise to exhaustion in normoxia and hypoxia (FiO2  = 12%)...
February 2015: Scandinavian Journal of Medicine & Science in Sports
Adriano R Tonelli, Laith Alkukhun, Vineesha Arelli, José Ramos, Jennie Newman, Kevin McCarthy, Bohdan Pichurko, Omar A Minai, Raed A Dweik
BACKGROUND: Methods that predict prognosis and response to therapy in pulmonary hypertension (PH) are lacking. We tested whether the noninvasive estimation of hemodynamic parameters during 6-minute walk test (6MWT) in PH patients provides information that can improve the value of the test. METHODS: We estimated hemodynamic parameters during the 6MWT using a portable, signal-morphology-based, impedance cardiograph (PhysioFlow Enduro) with real-time wireless monitoring via a bluetooth USB adapter...
December 2013: Clinical and Translational Science
Pascal Bogui, Edwige Balayssac-Siransy, Philippe Connes, Nalourgo Tuo, Soualiho Ouattara, Aurélien Pichon, Cyrille Serges Dah
The aim of the present study was to test the validity of the transthoracic electrical bioimpedance method PhysioFlow® to measure stroke volume in patients with chronic anemia. Stroke volume index (SVI), as well as cardiac index (CI) obtained by transthoracic electrical bioimpedance method and doppler echocardiography were compared in healthy subjects (n = 25) and patients with chronic anemia (i.e. mainly with sickle cell anemia; n = 32), at rest. While doppler echocardiography was able to detect difference in SVI between the two populations, the Physioflow® failed to detect any difference...
2013: PloS One
Guillaume Costalat, Jeremy Coquart, Ingrid Castres, Claire Tourny, Frederic Lemaitre
PURPOSE: Voluntary breath-holding (BH) elicits several hemodynamic changes, but little is known about maximal static immersed-body BH. We hypothesized that the diving reflex would be strengthened with body immersion and would spare more oxygen than maximal dry static BH, resulting in a longer BH duration. METHODS: Eleven trained breath-hold divers (BHDs) performed a maximal dry-body BH and a maximal immersed-body BH. Cardiac output (CO), stroke volume (SV), heart rate (HR), left ventricular end-diastolic volume (LVEDV), contractility index (CTI), and ventricular ejection time (VET) were continuously recorded by bio-impedancemetry (PhysioFlow PF-05)...
October 2013: European Journal of Applied Physiology
M Hallab, M Collette, C Terrier-Barbeau, M Legrand, P-H Ducluzeau, G Berrut, G Lefthériotis
PURPOSE: Aortic stiffness is a functional and structural consequence of ageing and arteriosclerosis. Regional arterial stiffness can be easily evaluated using pOpmetre(®) (Axelife SAS, France). This new technique assesses the pulse wave transit time (TT) between the finger (TTf) and the toe (TTt). Based on height chart, regional pulse wave velocity (PWV) between the toe and the finger can be estimated (PWVtf). pOpscore(®) index is also calculated as the ratio between PWVtoe and PWVfinger and can be considered as a peripheral vascular stiffness index...
June 2013: Annales de Cardiologie et D'angéiologie
Taira Fukuda, Akihiro Matsumoto, Miwa Kurano, Haruhito Takano, Haruko Iida, Toshihiro Morita, Hiroshi Yamashita, Yasunobu Hirata, Ryozo Nagai, Toshiaki Nakajima
The purpose of this study was to investigate the precise pattern of stroke volume (SV) response during exercise in patients with chronic heart failure (CHF) compared with age-matched controls. Fourteen patients with CHF and 7 controls performed symptom-limited bicycle exercise testing with respiratory gas exchange measurement. Patients were classified into group A (n = 7) with peak VO2 ≥ 18.0 mL/kg/minute and group B (n = 7) with peak VO2 < 18.0 mL/kg/ minute. SV and cardiac output (CO) were continuously measured during exercise using a novel thoracic impedance method (Physioflow)...
2012: International Heart Journal
Eloara M Ferreira, Jaquelina S Ota-Arakaki, Priscila B Barbosa, Ana Cristina B Siqueira, Daniela M Bravo, Carlos Eduardo B Kapins, Célia Maria C Silva, Luiz Eduardo Nery, J Alberto Neder
BACKGROUND: Haemodynamic responses to exercise are related to physical impairment and worse prognosis in patients with pulmonary arterial hypertension (PAH). It is clinically relevant, therefore, to investigate the practical usefulness of non-invasive methods of monitoring exercise haemodynamics in this patient population. METHODS: Using a novel impedance cardiography (ICG) approach that does not require basal impedance estimations and relies on a morphological analysis of the impedance signal (Signal-Morphology-ICG(™)), stroke volume (SV) and cardiac index (CI) were evaluated in 50 patients and 21 age-matched controls during a ramp-incremental cardiopulmonary exercise testing...
September 2012: Clinical Physiology and Functional Imaging
M K Vasilopoulou, I Vogiatzis, I Nasis, S Spetsioti, E Cherouveim, M Koskolou, E A Kortianou, Z Louvaris, G Kaltsakas, A Koutsoukou, N G Koulouris, M Alchanatis
Exercise-induced dynamic hyperinflation and large intrathoracic pressure swings may compromise the normal increase in cardiac output (Q) in Chronic Obstructive Pulmonary Disease (COPD). Therefore, it is anticipated that the greater the disease severity, the greater would be the impairment in cardiac output during exercise. Eighty COPD patients (20 at each GOLD Stage) and 10 healthy age-matched individuals undertook a constant-load test on a cycle-ergometer (75% WR(peak)) and a 6min walking test (6MWT). Cardiac output was measured by bioimpedance (PhysioFlow, Enduro) to determine the mean response time at the onset of exercise (MRTon) and during recovery (MRToff)...
May 31, 2012: Respiratory Physiology & Neurobiology
Katherine Taylor, Cedric Manlhiot, Brian McCrindle, Lars Grosse-Wortmann, Helen Holtby
BACKGROUND: Identification of low cardiac output (CO) states in anesthesia is important because preoperative hemodynamic optimization may improve outcome in surgery. Accurate real-time CO measurement would be useful in optimizing "goal-directed" therapy. We sought to evaluate the reliability and accuracy of CO measurement using bioimpedance cardiography (PhysioFlow®, NeuMeDx, Bristol, PA) in pediatric patients with and without cardiac disease undergoing anesthesia for magnetic resonance imaging (MRI)...
April 2012: Anesthesia and Analgesia
Katherine Taylor, Gustavo La Rotta, Brian W McCrindle, Cedric Manlhiot, Andrew Redington, Helen Holtby
OBJECTIVE(S): To evaluate the measurement of cardiac output (CO) using continuous electrical bioimpedance cardiography (Physioflow; Neumedx, Philadelphia, PA) (CO(PF)) with a simultaneous direct Fick measurement (CO(FICK)) in children with congenital heart disease. DESIGN: A prospective cohort study comparing 2 methods of measurement of CO. SETTING: A quaternary university-affiliated pediatric hospital. PARTICIPANTS: Children undergoing cardiac catheterization for clinical care...
October 2011: Journal of Cardiothoracic and Vascular Anesthesia
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