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https://www.readbyqxmd.com/read/29469470/-implementation-of-oncomelania-hupensis-monitoring-system-based-on-baidu-map
#1
Chen Zhi-Hua, Zhu Yi-Sheng, Xue Zhi-Qiang, Li Xue-Bing, Ding Yi-Min, Bi Li-Jun, Gao Kai-Min, Zhang You
OBJECTIVE: To construct the Oncomelania hupensis snail monitoring system based on the Baidu Map. METHODS: The environmental basic information about historical snail environment and existing snail environment, etc. was collected with the monitoring data about different kinds of O. hupensis snails, and then the O. hupensis snail monitoring system was built. Geographic Information System (GIS) and the electronic fence technology and Application Program Interface (API) were applied to set up the electronic fence of the snail surveillance environments, and the electronic fence was connected to the database of the snail surveillance...
October 25, 2017: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29467640/alterations-of-resting-state-static-and-dynamic-functional-connectivity-of-the-dorsolateral-prefrontal-cortex-in-subjects-with-internet-gaming-disorder
#2
Xu Han, Xiaowei Wu, Yao Wang, Yawen Sun, Weina Ding, Mengqiu Cao, Yasong Du, Fuchun Lin, Yan Zhou
Internet gaming disorder (IGD), a major behavior disorder, has gained increasing attention. Recent studies indicate altered resting-state static functional connectivity (FC) of the dorsolateral prefrontal cortex (DLPFC) in subjects with IGD. Whereas static FC often provides information on functional changes in subjects with IGD, investigations of temporal changes in FC between the DLPFC and the other brain regions may shed light on the dynamic characteristics of brain function associated with IGD. Thirty subjects with IGD and 30 healthy controls (HCs) matched for age, gender and education status were recruited...
2018: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/29467568/commentary-addressing-racial-disparities-in-stroke-the-wide-spectrum-investigation-of-stroke-outcome-disparities-on-multiple-levels-wissdom
#3
EDITORIAL
Robert J Adams, Charles Ellis, Gayenell Magwood, Mark S Kindy, Leonardo Bonilha, Daniel T Lackland
Racial-ethnic disparities in stroke recovery are well-established in the United States but the underlying causes are not well-understood. The typical assumption that racial-ethnic disparities in stroke recovery are explained by health care access inequities may be simplistic as access to stroke-related rehabilitation, for example, does not adequately explain the observed disparities. To approach the problem in a more comprehensive fashion, the Wide Spectrum Investigation of Stroke Outcome Disparities on Multiple Levels (WISSDOM) was developed to bring together scientists from Regenerative Medicine, Neurology, Rehabilitation, and Nursing to examine disparities in stroke "recovery...
2018: Ethnicity & Disease
https://www.readbyqxmd.com/read/29466316/approach-for-the-development-of-a-framework-for-the-identification-of-activities-of-daily-living-using-sensors-in-mobile-devices
#4
Ivan Miguel Pires, Nuno M Garcia, Nuno Pombo, Francisco Flórez-Revuelta, Susanna Spinsante
Sensors available on mobile devices allow the automatic identification of Activities of Daily Living (ADL). This paper describes an approach for the creation of a framework for the identification of ADL, taking into account several concepts, including data acquisition, data processing, data fusion, and pattern recognition. These concepts can be mapped onto different modules of the framework. The proposed framework should perform the identification of ADL without Internet connection, performing these tasks locally on the mobile device, taking in account the hardware and software limitations of these devices...
February 21, 2018: Sensors
https://www.readbyqxmd.com/read/29465594/understanding-the-productive-author-who-published-papers-in-medicine-using-national-health-insurance-database-a-systematic-review-and-meta-analysis
#5
Tsair-Wei Chien, Yu Chang, Hsien-Yi Wang
Many researchers used National Health Insurance database to publish medical papers which are often retrospective, population-based, and cohort studies. However, the author's research domain and academic characteristics are still unclear.By searching the PubMed database (Pubmed.com), we used the keyword of [Taiwan] and [National Health Insurance Research Database], then downloaded 2913 articles published from 1995 to 2017. Social network analysis (SNA), Gini coefficient, and Google Maps were applied to gather these data for visualizing: the most productive author; the pattern of coauthor collaboration teams; and the author's research domain denoted by abstract keywords and Pubmed MESH (medical subject heading) terms...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29464318/diffusion-mri-based-cortical-connectome-reconstruction-dependency-on-tractography-procedures-and-neuroanatomical-characteristics
#6
Michel R T Sinke, Willem M Otte, Daan Christiaens, Oliver Schmitt, Alexander Leemans, Annette van der Toorn, R Angela Sarabdjitsingh, Marian Joëls, Rick M Dijkhuizen
Diffusion MRI (dMRI)-based tractography offers unique abilities to map whole-brain structural connections in human and animal brains. However, dMRI-based tractography indirectly measures white matter tracts, with suboptimal accuracy and reliability. Recently, sophisticated methods including constrained spherical deconvolution (CSD) and global tractography have been developed to improve tract reconstructions through modeling of more complex fiber orientations. Our study aimed to determine the accuracy of connectome reconstruction for three dMRI-based tractography approaches: diffusion tensor (DT)-based, CSD-based and global tractography...
February 20, 2018: Brain Structure & Function
https://www.readbyqxmd.com/read/29463821/amygdala-hyper-connectivity-in-a-mouse-model-of-unpredictable-early-life-stress
#7
REVIEW
Frances K Johnson, Jean-Christophe Delpech, Garth J Thompson, Lan Wei, Jin Hao, Peter Herman, Fahmeed Hyder, Arie Kaffman
Childhood maltreatment is associated with a wide range of psychopathologies including anxiety that emerge in childhood and in many cases persist in adulthood. Increased amygdala activation in response to threat and abnormal amygdala connectivity with frontolimbic brain regions, such as the hippocampus and the prefrontal cortex, are some of the most consistent findings seen in individuals exposed to childhood maltreatment. The underlying mechanisms responsible for these changes are difficult to study in humans but can be elucidated using animal models of early-life stress...
February 21, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29459916/uv-induced-long-lived-decays-in-solvated-pyrimidine-nucleosides-resolved-at-the-ms-caspt2-mm-level
#8
Ana Julieta Pepino, Javier Segarra-Martí, Artur Nenov, Ivan Rivalta, Roberto Improta, Marco Garavelli
The most relevant 'dark' electronic excited states in DNA/RNA pyrimidine nucleosides are mapped in water employing hybrid MS-CASPT2/MM optimisations with explicit solvation and including the sugar. Conical intersections (CIs) between initially accessed bright1 ππ* and the lowest energy dark1 nπ* excited states, involving the lone pair localised on the oxygen and/or nitrogen atoms are characterised. They are found in the vicinities of the Franck-Condon (FC) region and are shown to facilitate non-adiabatic population transfer...
February 20, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29459252/multimodal-noninvasive-seizure-network-mapping-software-a-novel-tool-for-preoperative-epilepsy-evaluation
#9
Elliot G Neal, Stephanie Maciver, Fernando L Vale
BACKGROUND: Despite rigorous preoperative evaluation, epilepsy surgery achieves seizure freedom in only two-thirds of cases. Current preoperative evaluation does not include a detailed network analysis despite the association of network-level changes with epilepsy. OBJECTIVE: We sought to create a software algorithm to map individualized epilepsy networks by combining noninvasive electroencephalography (EEG) source localization and nonconcurrent resting state functional magnetic resonance imaging (rsfMRI)...
February 17, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29458355/healthy-parent-carers-programme-development-and-feasibility-of-a-novel-group-based-health-promotion-intervention
#10
Aleksandra J Borek, Bel McDonald, Mary Fredlund, Gretchen Bjornstad, Stuart Logan, Christopher Morris
BACKGROUND: Parent carers of disabled children report poor physical health and mental wellbeing. They experience high levels of stress and barriers to engagement in health-related behaviours and with 'standard' preventive programmes (e.g. weight loss programmes). Interventions promoting strategies to improve health and wellbeing of parent carers are needed, tailored to their specific needs and circumstances. METHODS: We developed a group-based health promotion intervention for parent carers by following six steps of the established Intervention Mapping approach...
February 20, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29456485/effect-of-spatial-smoothing-on-task-fmri-ica-and-functional-connectivity
#11
Zikuan Chen, Vince Calhoun
Spatial smoothing is a widely used preprocessing step in functional magnetic resonance imaging (fMRI) data analysis. In this work, we report on the spatial smoothing effect on task-evoked fMRI brain functional mapping and functional connectivity. Initially, we decomposed the task fMRI data into a collection of components or networks by independent component analysis (ICA). The designed task paradigm helps identify task-modulated ICA components (highly correlated with the task stimuli). For the ICA-extracted primary task component, we then measured the task activation volume at the task response foci...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29456256/clustering-the-orion-b-giant-molecular-cloud-based-on-its-molecular-emission
#12
Emeric Bron, Chloé Daudon, Jérôme Pety, François Levrier, Maryvonne Gerin, Pierre Gratier, Jan H Orkisz, Viviana Guzman, Sébastien Bardeau, Javier R Goicoechea, Harvey Liszt, Karin Öberg, Nicolas Peretto, Albrecht Sievers, Pascal Tremblin
Context: Previous attempts at segmenting molecular line maps of molecular clouds have focused on using position-position-velocity data cubes of a single molecular line to separate the spatial components of the cloud. In contrast, wide field spectral imaging over a large spectral bandwidth in the (sub)mm domain now allows one to combine multiple molecular tracers to understand the different physical and chemical phases that constitute giant molecular clouds (GMCs). Aims: We aim at using multiple tracers (sensitive to different physical processes and conditions) to segment a molecular cloud into physically/chemically similar regions (rather than spatially connected components), thus disentangling the different physical/chemical phases present in the cloud...
February 2018: Astronomy and Astrophysics
https://www.readbyqxmd.com/read/29455845/single-cell-resolution-of-t-cell-immune-responses
#13
Veit R Buchholz, Michael Flossdorf
Single antigen-specific B or T lymphocytes are the smallest functional units, into which an adaptive immune response can be dissected. Today, novel high-throughput technologies are providing researches with increasingly complex information on the diverse phenotypic signatures of individual lymphocytes. With a focus on T cells, we summarize here, how computational approaches are becoming increasingly important to identify the relevant developmental boundaries and connections between these high-dimensional lymphocyte states...
2018: Advances in Immunology
https://www.readbyqxmd.com/read/29455414/defining-g-protein-coupled-receptor-peptide-ligand-expressomes-and-signalomes-in-human-and-mouse-islets
#14
Patricio Atanes, Inmaculada Ruz-Maldonado, Ross Hawkes, Bo Liu, Min Zhao, Guo Cai Huang, Israa Mohammed Al-Amily, Albert Salehi, Stefan Amisten, Shanta J Persaud
INTRODUCTION: Islets synthesise and secrete numerous peptides, some of which are known to be important regulators of islet function and glucose homeostasis. In this study, we quantified mRNAs encoding all peptide ligands of islet G protein-coupled receptors (GPCRs) in isolated human and mouse islets and carried out in vitro islet hormone secretion studies to provide functional confirmation for the species-specific role of peptide YY (PYY) in mouse islets. MATERIALS AND METHODS: GPCR peptide ligand mRNAs in human and mouse islets were quantified by quantitative real-time PCR relative to the reference genes ACTB, GAPDH, PPIA, TBP and TFRC...
February 17, 2018: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/29454928/resting-state-functional-connectivity-of-the-amygdala-and-problem-drinking-in-non-dependent-alcohol-drinkers
#15
Sien Hu, Jaime S Ide, Herta H Chao, Simon Zhornitsky, Kimberly A Fischer, Wuyi Wang, Sheng Zhang, Chiang-Shan R Li
Alcohol misuse is associated with dysfunction of the amygdala-prefrontal cortical circuit. The amygdala and its cortical targets show decreased activity during a variety of task challenges in individuals engaged in problem drinking. On the other hand, it is less clear how amygdala resting state functional connectivity (rsFC) may be altered in association with alcohol misuse and whether such changes are restricted to prefrontal cortical structures. Further, the influences of comorbid substance use and depression and potential sex differences have not been assessed in earlier work...
February 7, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29454860/velocity-landscape-correlation-resolves-multiple-flowing-protein-populations-from-fluorescence-image-time-series
#16
Elvis Pandžić, Asmahan Abu-Arish, Renee W Whan, John W Hanrahan, Paul W Wiseman
Molecular, vesicular and organellar flows are of fundamental importance for the delivery of nutrients and essential components used in cellular functions such as motility and division. With recent advances in fluorescence/super-resolution microscopy modalities we can resolve the movements of these objects at higher spatio-temporal resolutions and with better sensitivity. Previously, spatio-temporal image correlation spectroscopy has been applied to map molecular flows by correlation analysis of fluorescence fluctuations in image series...
February 15, 2018: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/29451737/mapping-career-ready-skills-through-student-leadership-programs
#17
Adam Peck
This chapter discusses connecting learning outcomes already pursued in many leadership development programs with the skills that are most in-demand by employers. Additionally, the need to holistically map and integrate the career skills gained in both curricular and cocurricular contexts is explored, with models provided for implementing this approach.
March 2018: New Directions for Student Leadership
https://www.readbyqxmd.com/read/29451130/intrinsic-optical-signal-imaging-of-the-blood-volume-changes-is-sufficient-for-mapping-the-resting-state-functional-connectivity-in-the-rodent-cortex
#18
Sreekanth Kura, Hongyu Xie, Buyin Fu, Cenk Ayata, David A Boas, Sava Sakadzic
OBJECTIVE: Resting state functional connectivity (RSFC) allows the study of functional organization in normal and diseased brain by measuring the spontaneous brain activity generated under resting conditions. Intrinsic optical signal imaging (IOSI) based on multiple illumination wavelengths has been used successfully to compute RSFC maps in animal studies. The IOSI setup complexity would be greatly reduced if only a single wavelength can be used to obtain comparable RSFC maps. APPROACH: We used anesthetized mice and performed various comparisons between the RSFC maps based on single wavelength as well as oxy-, deoxy- and total hemoglobin concentration changes...
February 16, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29449773/potential-breast-anticancer-drug-targets-revealed-by-differential-gene-regulatory-network-analysis-and-molecular-docking-neoadjuvant-docetaxel-drug-as-a-case-study
#19
Adel Aloraini, Karim M ElSawy
Understanding gene-gene interaction and its causal relationship to protein-protein interaction is a viable route for understanding drug action at the genetic level, which is largely hindered by inability to robustly map gene regulatory networks. Here, we use biological prior knowledge of family-to-family gene interactions available in the KEGG database to reveal individual gene-to-gene interaction networks that underlie the gene expression profiles of 2 cell line data sets, sensitive and resistive to neoadjuvant docetaxel breast anticancer drug...
2018: Cancer Informatics
https://www.readbyqxmd.com/read/29448491/dynamical-characterization-of-transport-barriers-in-nontwist-hamiltonian-systems
#20
M Mugnaine, A C Mathias, M S Santos, A M Batista, J D Szezech, R L Viana
The turnstile provides us a useful tool to describe the flux in twist Hamiltonian systems. Thus, its determination allows us to find the areas where the trajectories flux through barriers. We show that the mechanism of the turnstile can increase the flux in nontwist Hamiltonian systems. A model which captures the essence of these systems is the standard nontwist map, introduced by del Castillo-Negrete and Morrison. For selected parameters of this map, we show that chaotic trajectories entering in resonances zones can be explained by turnstiles formed by a set of homoclinic points...
January 2018: Physical Review. E
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