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Sachin S Kumbhar, Ryan B O'Malley, Tracy J Robinson, Suresh Maximin, Neeraj Lalwani, David R Byrd, Carolyn L Wang
Optimal treatment of thyroid cancer is highly dependent on accurate staging of the extent of disease at presentation. Preoperative ultrasonography (US) is the most sensitive method for detecting metastatic lymph nodes and is recommended as part of the standard preoperative workup. Missed findings on preoperative scans may lead to understaging and inadequate surgical management, which subsequently predispose these patients to residual disease postoperatively and a higher risk for recurrence, possibly requiring repeat surgery...
October 21, 2016: Radiographics: a Review Publication of the Radiological Society of North America, Inc
Levente Rózsa, András Deák, Eszter Simon, Rocio Yanes, László Udvardi, László Szunyogh, Ulrich Nowak
We determined the parameters of a classical spin Hamiltonian describing an Fe monolayer on Pd(111) surface with a Pt_{1-x}Ir_{x} alloy overlayer from ab initio calculations. While the ground state of the system is ferromagnetic for x=0.00, it becomes a spin spiral state as Ir is intermixed into the overlayer. Although the Dzyaloshinsky-Moriya interaction is present in the system, we will demonstrate that the frustrated isotropic exchange interactions play a prominent role in creating the spin spiral state, and these frustrated couplings lead to an attractive interaction between Skyrmions at short distances...
October 7, 2016: Physical Review Letters
Volker Wenzel, Nikolaus Gravenstein
PURPOSE OF REVIEW: Mentoring is fundamentally valuable and important to students considering a path into our specialty, as well as to colleagues already in it and with ambition to advance. General principles and personal experiences are collected and described to help inform future mentors and to reinforce the value of having a mentor and the satisfaction (and work) that is associated with such a role. RECENT FINDINGS: Detecting a latent talent among medical students or residents may be challenging but is worth the effort to develop personal careers and the specialty itself...
October 18, 2016: Current Opinion in Anaesthesiology
Rachelle Hornby
I began watching the BBC's Panorama documentary Diabetes: The Hidden Killer but got frustrated and had to turn it off. I have had type 1 diabetes for 28 years and am shocked at the resources thrown at people with type 2, which can easily be prevented. This funding would be better used on research into type 1 diabetes and its treatment.
October 12, 2016: Nursing Standard
Bayo Aluko-Olokun, Ademola Abayomi Olaitan
The literature on keloids is replete with authors expressing frustration with treatment results. Triamcinolone is effective in shrinking keloids and preventing their recurrence following excision, if delivered successfully. Strategies for effective delivery of drug are presented: recommended needle size, use of metal syringe, slow injection to avoid skin rupture, and delayed withdrawal of needle after injection. The futility of expecting pedunculated keloids to be completely flattened by steroid injection alone is mentioned...
October 14, 2016: Journal of Craniofacial Surgery
Eva Dye, Nancy Wells
BACKGROUND: Neonatal nurse practitioner (NNP) workload is not well studied, and metrics specific to NNP practice are lacking. Factors such as changes in resident duty hours, increasing neonatal intensive care unit admissions, and a shortage of NNPs contribute to NNP workload. Increased workload has been shown to be detrimental to providers and can affect quality of care. PURPOSE: This study quantified NNP workload using a subjective workload metric, the NASA Task Load Index, and a newly developed objective workload metric specific to NNP practice...
October 13, 2016: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
Gisselle Gallego, Angela Dew, Michelle Lincoln, Anita Bundy, Rebecca Jean Chedid, Kim Bulkeley, Jennie Brentnall, Craig Veitch
In Australia and around the world, people with disability and their carers living in rural areas face additional challenges compared to their urban-dwelling counterparts. This cross-sectional study explored current access to therapy services for people with disability living in western New South Wales as reported by their primary carers. Data were collected using an online and paper survey distributed to carers, from December 2012 until June 2013. Information was sought about the carers, the person they care for, access to physiotherapy, speech pathology, occupational therapy and psychology services...
October 17, 2016: Health & Social Care in the Community
Rachel Newby, Jane Alty, Peter Kempster
Mind-brain dualism has dominated historical commentary on dystonia, a dichotomous approach that has left our conceptual grasp of it stubbornly incomplete. This is particularly true of functional dystonia, most diagnostically challenging of all functional movement disorders, in which the question of inherent psychogenicity remains a focus of debate. Phenomenological signs considered in isolation lack the specificity to distinguish organic and nonorganic forms, and dystonia's variability has frustrated attempts to develop objective laboratory-supported standards...
October 18, 2016: Movement Disorders: Official Journal of the Movement Disorder Society
Yi Chen, Yue Ban, Qi-Biao Zhu, Xi Chen
Graphene-assisted resonant transmission and enhanced Goos-Hänchen shift are investigated in a two-prism frustrated total internal reflection configuration. Due to the excitation of surface plasmons induced by graphene in a low terahertz frequency range, there exist the resonant transmission and anomalous Goos-Hänchen shifts in such an optical tunneling configuration. As compared to the case of the quantum well, a graphene sheet with unique optical properties can enhance the resonant transmission with a relatively low loss and modulate the large negative and positive Goos-Hänchen shifts by adjusting the chemical potential or electron relaxation time...
October 1, 2016: Optics Letters
Naiyin Yu, Abhijit Ghosh, Michael F Hagan
We use computer simulations and simple theoretical models to analyze the morphologies that result when rod-like particles end-attach onto a curved surface, creating a finite-thickness monolayer aligned with the surface normal. This geometry leads to two forms of frustration, one associated with the incompatibility of hexagonal order on surfaces with Gaussian curvature, and the second reflecting the deformation of a layer with finite thickness on a surface with non-zero mean curvature. We show that the latter effect leads to a faceting mechanism...
October 17, 2016: Soft Matter
Raúl Alelú-Paz, Francisco J Carmona, José V Sanchez-Mut, Ariel Cariaga-Martínez, Ana González-Corpas, Nadia Ashour, Maria J Orea, Ana Escanilla, Alfonso Monje, Carmen Guerrero Márquez, Jerónimo Saiz-Ruiz, Manel Esteller, Santiago Ropero
Attempts to discover genes that are involved in the pathogenesis of major psychiatric disorders have been frustrating and often fruitless. Concern is building about the need to understand the complex ways in which nature and nurture interact to produce mental illness. We analyze the epigenome in several brain regions from schizophrenic patients with severe cognitive impairment using high-resolution (450K) DNA methylation array. We identified 139 differentially methylated CpG sites included in known and novel candidate genes sequences as well as in and intergenic sequences which functions remain unknown...
2016: Frontiers in Psychology
Brian S Barnett, Macjellings Mulenga, Michelle M Kiser, Anthony G Charles
OBJECTIVE: While psychological care, including supportive group therapy, is a mainstay of burn treatment in the developed world, few reports of support groups for burn survivors and their caregivers in the developing world exist. This study records the findings of a support group in Malawi and provides a qualitative analysis of thematic content discussed by burn survivors and caregivers. MATERIALS AND METHODS: We established a support group for burn survivors and caregivers from February-May 2012 in the burn unit at Kamuzu Central Hospital in Lilongwe, Malawi...
October 12, 2016: Burns: Journal of the International Society for Burn Injuries
John V Thomas, Rupan Sanyal, Janis P O'Malley, Satinder P Singh, Desiree E Morgan, Cheri L Canon
The academic educator's portfolio is a collection of materials that document academic performance and achievements, supplementing the curriculum vitae, in order to showcase a faculty member's most significant accomplishments. A decade ago, a survey of medical schools revealed frustration in the nonuniform methods of measuring faculty's medical education productivity. A proposed solution was the use of an academic educator's portfolio. In the academic medical community, compiling an academic portfolio is always a challenge because teaching has never been confined to the traditional classroom setting and often involves active participation of the medical student, resident, or fellow in the ongoing care of the patient...
October 11, 2016: Academic Radiology
Kathleen A Kennedy, C Michael Cotten, Kristi L Watterberg, Waldemar A Carlo
Despite remarkable improvements in survival of extremely premature infants, the burden of BPD among survivors remains a frustrating problem for parents and caregivers. Advances, such as antenatal steroids and surfactant replacement, which have dramatically improved survival, have not reduced BPD among survivors. Other advances that have significantly improved the combined outcome of death or BPD, such as vitamin A and avoidance of mechanical ventilation, have had smaller magnitude effects on the outcome of BPD alone...
October 2016: Seminars in Perinatology
Chol-Ung Choe, Ji-Song Ri, Ryong-Son Kim
We suggest a site disorder model that describes the population of identical oscillators with quenched random interactions for both the coupling strength and coupling phase. We obtain the reduced equations for the suborder parameters, on the basis of Ott-Antonsen ansatz theory, and present a complete bifurcation analysis of the reduced system. New effects include the appearance of the incoherent chimera and glassy state, both of which are caused by heterogeneity of the coupling phases. In the incoherent chimera state, the system displays an exotic symmetry-breaking behavior in spite of the apparent structural symmetry where the oscillators for both of the two subpopulations are in a frustrated state, while the phase distribution for each subpopulation approaches a steady state that differs from each other...
September 2016: Physical Review. E
W Michael Pullen, Nicholas J Erdle, Colin Crickard, Christopher S Smith
Intramedullary tibial fixation is a commonly used and highly successfully treatment in acute fractures, nonunion settings, and correctional procedures. In the setting of a nonunion, removal of a failed implant can add to operative time and surgeon frustration while further compromising bone in an area already at risk for failure. Here we present a technique, using readily accessible equipment, for removing a distal solid tibial nail fragment in a manner that preserves bone.
September 2016: American Journal of Orthopedics
Jolene van der Kaap-Deeder, Maarten Vansteenkiste, Bart Soenens, Elien Mabbe
This study examined the unique relations between multiple sources (i.e., mothers, teachers, and siblings) of perceived daily autonomy support and psychological control and children's basic psychological needs and well-being. During 5 consecutive days, 2 children from 154 families (Mage youngest child = 8.54 years; SD = .89 and Mage oldest child = 10.38 years; SD = .87) provided daily ratings of the study variables. Multilevel analyses showed that each of the sources of perceived autonomy support and psychological control related uniquely to changes in daily well-being and ill-being...
October 13, 2016: Developmental Psychology
Alison C McQuilken, Quang Minh Dao, Allan Jay P Cardenas, Jeffery A Bertke, Stefan Grimme, Timothy H Warren
We report a new class of frustrated Lewis pairs (FLPs) by the hydroboration of bulky isocyanates (iPr2) ArNCO ((iPr2) Ar=2,6-iPr2 C6 H3 ) and (Ph2tBu) ArNCO ((Ph2tBu) Ar=2,6-Ph2 -4-tBuC6 H2 ) with Piers' borane (HB(C6 F5 )2 ). While hydroboration of smaller isocyanates such as (iPr2) ArNCO leads to isocyanate-N/B FLP adducts, hydroboration of the bulkier (Ph2tBu) ArNCO allows isolation of the substrate-free aminoborane with a short, covalent N-B bond. This confused FLP reversibly binds unsaturated substrates such as isocyanates and isocyanides, suggesting the intermediacy of a "normal" FLP along the reaction pathway, supported by high-level DFT studies and variable-temperature NMR spectroscopy...
October 13, 2016: Angewandte Chemie
R Wells, A Tonkin
Patients with autonomic dysfunction may present with a variety of seemingly unrelated symptoms, both generalised and involving specific systems, including fatigue, difficulty concentrating, orthostatic intolerance, palpitations, constipation or diarrhoea, early satiety, urinary retention or incontinence and erectile dysfunction. Failure to connect the diverse symptoms with a single underlying mechanism may lead to incorrect diagnoses, inappropriate interventions and frustration on the part of both doctors and patients...
October 2016: Internal Medicine Journal
Clélia M Bianchi, Jean-François Huneau, Gaëlle Le Goff, Eric O Verger, François Mariotti, Patricia Gurviez
BACKGROUND: From a life course perspective, pregnancy leads to a rise in nutrition awareness and an increase in information flow in favour of adopting healthier eating behaviours. This qualitative study was designed to better understand the determinants of eating behaviours in French pregnant women by focusing on their concerns, attitudes and beliefs and their nutrition-related information seeking practices. METHODS: Seven focus groups were conducted, involving a total of 40 French pregnant women...
October 12, 2016: BMC Pregnancy and Childbirth
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