keyword
https://read.qxmd.com/read/38448170/-multiple-pulmonary-nodules-with-cavity-formation
#21
JOURNAL ARTICLE
X Y Shi, L L Xu, Y L Gao, Q H Fang, R E Feng, L An
A 64-year-old female patient was admitted to Beijing Chao-Yang Hospital on February 21, 2023 because of right-sided chest pain for more than 4 years and left-sided chest pain for more than 9 months. She had a past medical history of previous tuberculosis and rheumatoid arthritis. A chest CT in October 2018 revealed multiple pulmonary nodules. A CT-guided biopsy showed no tumors, and adenosine deaminase levels in the pleural effusion were elevated, suggesting a high likelihood of tuberculosis. As a result, anti-tuberculosis treatment was initiated in March 2019...
March 12, 2024: Chinese Journal of Tuberculosis and Respiratory Diseases
https://read.qxmd.com/read/38447437/validation-of-the-familial-chylomicronaemia-syndrome-fcs-score-in-an-ethnically-diverse-cohort-from-uk-fcs-registry-implications-for-diagnosis-and-differentiation-from-multifactorial-chylomicronaemia-syndrome-mcs
#22
JOURNAL ARTICLE
Bilal Bashir, See Kwok, Anthony S Wierzbicki, Alan Jones, Charlotte Dawson, Paul Downie, Fiona Jenkinson, Hannah Delaney, Michael Mansfield, Dev Datta, Yee Teoh, Paul Hamilton, Natalie Forrester, Dawn O'Sullivan, Maryam Ferdousi, Paul N Durrington, Alaa AbdelRazik, Antonio Gallo, Philippe Moulin, Handrean Soran
BACKGROUND AND AIMS: Prognosis and management differ between familial chylomicronaemia syndrome (FCS), a rare autosomal recessive disorder, and multifactorial chylomicronaemia syndrome (MCS) or severe mixed hyperlipidaemia. A clinical scoring tool to differentiate these conditions has been devised but not been validated in other populations. The objective of this study was to validate this score in the UK population and identify any additional factors that might improve it. METHODS: A retrospective validation study was conducted using data from 151 patients comprising 75 FCS and 76 MCS patients...
February 10, 2024: Atherosclerosis
https://read.qxmd.com/read/38444126/impact-of-the-covid-19-pandemic-and-perception-of-self-efficacy-on-the-mental-health-of-out-of-hospital-emergency-healthcare-professionals-by-modality-of-care
#23
JOURNAL ARTICLE
Rosa María Cárdaba-García, Raúl Soto-Cámara, Noemi García-Santa-Basilia, María Paz Matellán-Hernández, Henar Onrubia-Baticón, Carmen María Martínez-Caballero, Israel John Thuissard-Vasallo, Susana Navalpotro-Pascual
OBJECTIVE: To analyse the influence of the COVID-19 pandemic and the perception of self-efficacy on the health professionals of the Spanish out-of-hospital emergency services. DESIGN: Observational, cross-sectional and descriptive with a survey methodology of 1710 participants from Spain (1 February-30 April, 2021). METHODS: The mental health of healthcare workers was assesed in terms of stress, anxiety and depression, as well as their self-efficacy...
March 5, 2024: Journal of Advanced Nursing
https://read.qxmd.com/read/38442834/innovative-modification-of-cellulose-fibers-for-paper-based-electrode-materials-using-metal-organic-coordination-polymers
#24
JOURNAL ARTICLE
Ziyang Chang, Dingqiang Liang, Shirong Sun, Shuo Zheng, Kexin Sun, Haiping Wang, Yanguang Chen, Daliang Guo, Huifang Zhao, Lizheng Sha, Wenyan Jiang
Cellulosic paper-based electrode materials have attracted increasing attention in the field of flexible supercapacitor. As a conductive polymer, polyaniline exhibits high theoretical pseudocapacitive capacitance and has been applied in paper-based electrode materials along with cellulose fibers. However, the stacking of polyaniline usually leads to poor performance of electrodes. In this study, metal-organic coordination polymers of zirconium-alizarin red S and zirconium-phytic acid are applied to modulate the polyaniline layer to obtain high-performance cellulosic paper-based electrode materials...
March 3, 2024: International Journal of Biological Macromolecules
https://read.qxmd.com/read/38439890/peer-education-program-to-improve-fluid-consumption-in-primary-schools-lessons-learned-from-an-innovative-pilot-study
#25
JOURNAL ARTICLE
Zs Soósné Kiss, J Vitrai, J Takács, J Á Lukács, A Falus, H J Feith
BACKGROUND: Although it is widely recognized that more attention needs to be paid to children's fluid intake, there is little information on how to improve it. Peer education has been suggested as an effective approach to changing health behaviors among school children. As a new approach, our study piloted a peer education program to improve children's fluid intake in primary schools. METHODS: University students were prepared for their role as peer educators in an elective university course, including the concept of peer education and different pedagogical methods...
March 15, 2024: Heliyon
https://read.qxmd.com/read/38434063/improved-neural-network-with-multi-task-learning-for-alzheimer-s-disease-classification
#26
JOURNAL ARTICLE
Xin Zhang, Le Gao, Zhimin Wang, Yong Yu, Yudong Zhang, Jin Hong
Alzheimer's disease(AD) poses a significant challenge due to its widespread prevalence and the lack of effective treatments, highlighting the urgent need for early detection. This research introduces an enhanced neural network, named ADnet, which is based on the VGG16 model, to detect Alzheimer's disease using two-dimensional MRI slices. ADNet incorporates several key improvements: it replaces traditional convolution with depthwise separable convolution to reduce model parameters, replaces the ReLU activation function with ELU to address potential issues with exploding gradients, and integrates the SE(Squeeze-and-Excitation) module to enhance feature extraction efficiency...
February 29, 2024: Heliyon
https://read.qxmd.com/read/38431817/abuse-of-right-during-application-of-coercive-medical-measures-in-criminal-proceedings
#27
JOURNAL ARTICLE
Vira V Navrotska, Oksana P Horpyniuk, Halyna D Boreiko
OBJECTIVE: Aim: To determine the problematic issues of ensuring the rights and freedoms of persons suffering from mental disorders and to whom CMM are applied in criminal proceedings under the legislation of Ukraine and the legislation of the states that adhere to the modern concepts of international standards of human rights ensuring to a person the CMM are applied to. PATIENTS AND METHODS: Materials and Methods: Legal positions of the ECHR, criminal procedural legislation of a number of states, and a survey of scientists and practitioners conducted by the authors are used in this paper (total number of respondents was 168)...
2024: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://read.qxmd.com/read/38423934/trust-in-the-icu-what-every-clinician-should-know
#28
REVIEW
Abdul W Kazi, Erika J Yoo, David Oxman
Trust is an essential element in the relationship between patients and intensive care unit (ICU) clinicians. Without a foundation of trust, communication is difficult, conflict is more likely, and even clinical outcomes can be affected. The ICU is a particularly challenging environment for trust to flourish. Illness occurs suddenly, emotions can be charged, the environment is impersonal, and there is rarely a prior relationship between patients and their caregivers. Therefore, intensivists must have some understanding of the factors that impact patient and family trust, as well as the actions they can take to improve it...
February 28, 2024: Journal of Critical Care
https://read.qxmd.com/read/38416241/microfluidic-chip-immunoassay-based-on-rolling-circle-amplification-and-g-quadruplex-thioflavin-t-for-multiplex-detection-of-ctx-i
#29
JOURNAL ARTICLE
Hao Jiang, Xuefei Lv, Shuyu Lu, Yue Yu, Anyi Li, Xiaoqiong Li, Yulin Deng
A label-free immunoassay based on rolling circle amplification (RCA) and G-quadruplex/Thioflavin T (G4/ThT) is proposed to realize the sensitive detection of carboxy-terminal cross-linked fragment of type I collagen (CTX I) for bone loss. Under the optimal conditions, as low as 38.02 pg/mL of CTX I can be detected. To improve the detecting throughput and simplify the operation, a microfluidic chip was designed, fabricated, and used for CTX I detection based on the proposed assay. The detection can be completed with only a single on-chip magnetic separation step, which was easy to operate, less time-consuming, and has only low reagent consumption...
February 28, 2024: Mikrochimica Acta
https://read.qxmd.com/read/38410301/professionalism-program-evaluation-and-its-impact-on-undergraduate-medical-students
#30
JOURNAL ARTICLE
Sarah Amin, Sundus Ambreen, Noor Ul-Ain, Tasneem Murad, Khadeejah Sajwani, Aasma Qaiser
Objective The study aims to evaluate the effectiveness of a professionalism program by conducting focus group discussions (FGDs). The research focuses on understanding how the program influences the development of professionalism skills among medical students, as well as their perceptions and experiences regarding the program. The study's objectives revolve around identifying the strengths and weaknesses of the program from the perspective of the students. Methods This was a qualitative study done after obtaining approval from the Institutional Review Committee, Islamic International Medical College...
January 2024: Curēus
https://read.qxmd.com/read/38408738/longitudinal-speech-outcome-at-5-and-10-years-in-uclp-influence-of-speech-therapy-and-secondary-velopharyngeal-surgery
#31
JOURNAL ARTICLE
C Persson, J Davies, C Havstam, H Søgaard, M Bowden, M Boers, J B Nielsen, S Alaluusua, I Lundeborg Hammarström, B K Emborg, A Sand, A Lohmander
OBJECTIVE: To investigate speech development of children aged 5 and 10 years with repaired unilateral cleft lip and palate (UCLP) and identify speech characteristics when speech proficiency is not at 'peer level' at 10 years. Estimate how the number of speech therapy visits are related to speech proficiency at 10 years, and what factors are predictive of whether a child's speech proficiency at 10 years is at 'peer level' or not. DESIGN: Longitudinal complete datasets from the Scandcleft project...
February 26, 2024: Cleft Palate-craniofacial Journal
https://read.qxmd.com/read/38400109/covid-19-vaccination-coverage-and-associated-factors-in-patients-with-multiple-sclerosis
#32
JOURNAL ARTICLE
Ignacio Hernández-García, Joana Rodríguez-Montolio, Monserrath Almeida-Zurita, Dionisio Cheli-Gracia, Belén Del Moral Sahuquillo, Carlos Aibar-Remón, Moisés Garcés-Redondo
Our objective was to know the COVID-19 vaccination coverage in multiple sclerosis (MS) patients and its factors associated. A retrospective cohort study was carried out. Patients seen at the MS unit of the University Clinical Hospital of Zaragoza between 2017 and 2021 were included. Variables were obtained by reviewing the specialized and primary care records. Associations between receiving COVID-19 full primo-vaccination, as well as one booster dose since autumn 2022, and the other variables were analyzed using bivariate analysis and multiple logistic regression models...
January 26, 2024: Vaccines
https://read.qxmd.com/read/38399296/sample-size-requirements-of-a-pharmaceutical-material-library-a-case-in-predicting-direct-compression-tablet-tensile-strength-by-latent-variable-modeling
#33
JOURNAL ARTICLE
Junjie Cao, Haoran Shen, Shuying Zhao, Xiao Ma, Liping Chen, Shengyun Dai, Bing Xu, Yanjiang Qiao
The material library is an emerging, new data-driven approach for developing pharmaceutical process models. How many materials or samples should be involved in a particular application scenario is unclear, and the impact of sample size on process modeling is worth discussing. In this work, the direct compression process was taken as the research object, and the effects of different sample sizes of material libraries on partial least squares (PLS) modeling in the prediction of tablet tensile strength were investigated...
February 7, 2024: Pharmaceutics
https://read.qxmd.com/read/38391841/quality-of-life-and-treatment-modalities-in-patients-with-interstitial-cystitis-the-patients-perspective
#34
JOURNAL ARTICLE
Charlotte van Ginkel, Frank Martens, Mathilde Scholtes, John Heesakkers, Dick A W Janssen
BACKGROUND: Quality of life (QoL)-based outcomes are hardly incorporated into interstitial cystitis/bladder pain syndrome (IC/BPS) guidelines, because studies are limited and outdated. Therefore, guidelines might not reflect the current clinical situation accurately. Secondly, guidelines suggest using a multimodal approach for BPS/IC management, but data on the patient-perceived efficacy of these therapies are limited. The aim of this study is to investigate the perception of IC/BPS patients of their QoL, to determine which treatments they have received, and to examine how they evaluate the efficacy of these various (alternative) therapies...
February 13, 2024: Healthcare (Basel, Switzerland)
https://read.qxmd.com/read/38388359/visual-migraine-aura-iconography-a-multicentre-cross-sectional-study-of-individuals-with-migraine-with-aura
#35
MULTICENTER STUDY
Michele Viana, Anders Hougaard, Erling Tronvik, Ingunn Grøntveit Winnberg, Anna Ambrosini, Armando Perrotta, Thien Phu Do, Mohammad Al-Mahdi Al-Karagholi, Mikhail Fominykh, Shairin Sihabdeen, Claudio Gobbi, Chiara Zecca
INTRODUCTION: Visual disturbances are the most common symptoms of migraine aura. These symptoms can be described systematically by subdividing them into elementary visual symptoms. Since visual symptoms of migraine aura are not easy to describe verbally, we developed a collection of images illustrating previously reported elementary visual symptoms. OBJECTIVES: To test a standardised visual migraine aura iconography in a large population of migraine with aura patients and to improve it based on the participants' feedback...
February 2024: Cephalalgia: An International Journal of Headache
https://read.qxmd.com/read/38385236/-research-progress-on-early-postoperative-pain-management-strategies-after-arthroscopic-anterior-cruciate-ligament-reconstruction
#36
JOURNAL ARTICLE
Hong Yu, Zhengliang Shi, Bohan Xiong, Yajuan Li, Yihua Qin, Kaiyan Dong, Yanlin Li, Li Li
OBJECTIVE: To summarize the early postoperative pain management strategies for anterior cruciate ligament reconstruction (ACLR), and to select a reasonable and effective pain management plan to promote functional rehabilitation after ACLR. METHODS: The literature about the early postoperative pain management strategies of ACLR both domestically and internationally in recent years was extensiverly reviewed, and the effects of improving postoperative pain were reviewed...
February 15, 2024: Chinese Journal of Reparative and Reconstructive Surgery
https://read.qxmd.com/read/38380885/bright-fluorescent-p-phenylene-bridged-triarylmethyl-highly-stable-diradical
#37
JOURNAL ARTICLE
Yohei Hattori, Kohei Yamamoto, Ryota Kitajima, Kingo Uchida
Two units of highly stable luminescent triarylmethyl radical, (3,5-dichloro-4-pyridyl)bis(2,4,6-trichlorophenyl)methyl radical (PyBTM), were bridged by p-phenylene linker. The photoluminescence quantum yield (PLQY) of PyBTM-PhPyBTM was at most 0.4% in various organic solvents. Adding two mesityl groups on the terminals did not improve the PLQY. In the MesPyBTM-PhPyBTM-Mes, the mesityl group did not worked as an electron donor unlike the previously reported monoradical MesPyBTM. However, adding two n-hexyl groups on the bridging p-phenylene did greatly improve it, and the PLQY of the PyBTM-(Hex2Ph)PyBTM was 7% in dichloromethane and acetone, and 12% in poly(methyl methacrylate) (PMMA) film...
February 21, 2024: Chemistry: a European Journal
https://read.qxmd.com/read/38365733/development-implementation-and-evaluation-of-the-effectiveness-of-an-intervention-program-to-improve-the-sexual-competence-of-young-adult-women-about-to-get-married-a-protocol-study
#38
JOURNAL ARTICLE
Zahra Sadat Mousavi, Mojgan Janighorban, Mahnaz Noroozi
BACKGROUND: Having competence in initiating sexual interactions is one of the challenges of sexual health in any society. Given that the social, cultural, and religious background of some societies can prevent the acquisition of sexual competence in young women, this study will be done to design, implement, and determine the effectiveness of an intervention program to improve the sexual competence of young women on the eve of marriage. METHODS: The current research is a mixed-method study in a qualitative-quantitative sequence...
February 16, 2024: Reproductive Health
https://read.qxmd.com/read/38356800/understanding-ethics-of-reporting-health-related-events-in-media-a-qualitative-phenomenological-study-in-karachi-and-peshawar
#39
JOURNAL ARTICLE
Shiraz Shaikh, Aroosa Nadeem, Mehjabeen Musharraf, Sheraz Fazid
OBJECTIVE: The specific objectives of this study were to identify the ethical issues in reporting of health-related events in media and suggest ways to improve it. METHOD: This was a qualitative phenomenological study conducted by APPNA Institute of Public Health, Jinnah Sindh Medical University in collaboration with Institute of Public Health, Khyber Medical University from January to April 2022. A total of 38 focus group discussions and in-depth interviews were conducted either face to face at place of convenience of interviewees or online...
2024: Pakistan Journal of Medical Sciences Quarterly
https://read.qxmd.com/read/38355236/atherogenic-risk-assessment-can-we-improve-it
#40
JOURNAL ARTICLE
José Puzo Foncillas
No abstract text is available yet for this article.
2024: Clínica e Investigación en Arteriosclerosis
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