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https://www.readbyqxmd.com/read/29792119/maple-2-3-0-an-improved-system-for-evaluating-the-functionomes-of-genomes-and-metagenomes
#1
Wataru Arai, Takeaki Taniguchi, Susumu Goto, Yuki Moriya, Hideya Uehara, Kazuhiro Takemoto, Hiroyuki Ogata, Hideto Takami
MAPLE is an automated system for inferring the potential comprehensive functions harbored by genomes and metagenomes. To reduce runtime in MAPLE analyzing the massive amino acid datasets of over 1 million sequences, we improved it by adapting the KEGG automatic annotation server to use GHOSTX and verified no substantial difference in the MAPLE results between the original and new implementations.
May 24, 2018: Bioscience, Biotechnology, and Biochemistry
https://www.readbyqxmd.com/read/29792082/mining-concepts-of-health-responsibility-using-text-mining-and-exploratory-graph-analysis
#2
Sofia Kjellström, Hudson Golino
BACKGROUND: Occupational therapists need to know about people's beliefs about personal responsibility for health to help them pursue everyday activities. AIM: The study aims to employ state-of-the-art quantitative approaches to understand people's views of health and responsibility at different ages. METHODS: A mixed method approach was adopted, using text mining to extract information from 233 interviews with participants aged 5 to 96 years, and then exploratory graph analysis to estimate the number of latent variables...
May 24, 2018: Scandinavian Journal of Occupational Therapy
https://www.readbyqxmd.com/read/29788928/residents-breastfeeding-knowledge-comfort-practices-and-perceptions-results-of-the-breastfeeding-resident-education-study-brest
#3
Elizabeth Esselmont, Katherine Moreau, Mary Aglipay, Catherine M Pound
BACKGROUND: Physicians have a significant impact on new mothers' breastfeeding practices. However, physicians' breastfeeding knowledge is suboptimal. This knowledge deficit could be the result of limited breastfeeding education in residency. This study aimed to explore pediatric residents' breastfeeding knowledge, comfort level, clinical practices, and perceptions. It also investigated the level and type of education residents receive on breastfeeding and their preferences for improving it...
May 22, 2018: BMC Pediatrics
https://www.readbyqxmd.com/read/29783228/awareness-of-pediatric-palliative-care-among-health-care-workers
#4
Oryna Z Detsyk, Zhanna M Zolotarova, Iryna V Stovban, Roman M Melnyk
OBJECTIVE: Introduction: In order to develop such a relatively new type of medical care in Ukraine, as pediatric palliative care, first of all, qualified medical workers are needed. The aim: to assess the awareness of pediatric palliative care among healthcare workers providing medical services to children. PATIENTS AND METHODS: Materials and methods: It was carried out a survey at health facilities of Ivano-Frankivsk region, which provided medical care for children...
2018: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29781922/screening-for-sexually-transmitted-infections-after-cervical-cancer-screening-guideline-and-medicaid-policy-changes-a-population-based-analysis
#5
Natasha Parekh, Julie M Donohue, Jennifer Corbelli, Aiju Men, David Kelley, Marian Jarlenski
BACKGROUND: Sexually transmitted infection (STI) screening prevents complications and is cost-effective. Annual screening is recommended in sexually active women <25 years and older women at increased risk. Cervical cancer (CC) screening guideline changes in 2009 and 2012 recommended less frequent screening, causing concern that STI screening would decrease. Pennsylvania Medicaid implemented a family planning program in 2007 which covered women's health services (including STI testing) for uninsured women...
May 17, 2018: Medical Care
https://www.readbyqxmd.com/read/29775628/-cost-effectiveness-of-interventions-to-improve-hand-hygiene-in-healthcare-workers-in-middle-income-hospital-settings-a-model-based-analysis
#6
Nantasit Luangasanatip, Maliwan Hongsuwan, Yoel Lubell, Direk Limmathurotsakul, Pramot Srisamang, Nicholas Pj Day, Nicholas Graves, Ben S Cooper
BACKGROUND: Multimodal interventions are effective in increasing hand hygiene (HH) compliance amongst healthcare workers, but it is not known whether such interventions are cost-effective outside high-income countries. AIM: To evaluate the cost-effectiveness of multimodal hospital interventions to improve hand hygiene (HH) compliance in a middle-income country. METHOD: We adopted a conservative approach by developing a model to determine whether reductions in Methicillin-resistant Staphylococcus aureus bloodstream infections (MRSA-BSI) alone would make HH interventions cost-effective in intensive care units (ICUs)...
May 15, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29770667/-clinical-characteristics-of-16-newly-discovered-advanced-schistosomiasis-patients-in-dongpo-district-meishan-city-sichuan-province
#7
Zhou Zhi, Xu Jia, Zhang Yi
OBJECTIVE: To understand the clinical characteristics of newly discovered advanced schistosomiasis patients in Dongpo District, Meishan City, Sichuan Province, so as to provide the reference for enhancing the clinicians' awareness for diagnosis and treatment of this disease and improving the therapeutic effect. METHODS: The data of medical records and schedule of case survey of 16 newly discovered advanced schistosomiasis patients in Dongpo District, Meishan City, Sichuan Province were collected and analyzed...
April 17, 2018: Zhongguo Xue Xi Chong Bing Fang Zhi za Zhi, Chinese Journal of Schistosomiasis Control
https://www.readbyqxmd.com/read/29769464/-a-case-study-of-tailor-made-exercise-for-preventing-decrease-in-physical-function-analyzing-the-effect-of-tailor-made-exercise-from-a-motion-study-motor-function-test-and-questionnaire
#8
Naomichi Tani, Yoshiyuki Higuchi, Masanori Ohta, Zyunichi Akathu, Masaharu Kumashiro
OBJECTIVE: This study aimed to verify the effect of tailor-made exercise depending on the characteristics of a certain food manufacturing industry on the physical function and subjective symptoms of employees. METHODS: For the development of tailor-made exercise, work analysis was carried out at each factory to comprehend the physical burden due to work load. The motor function test and questionnaire survey for subjective symptoms were conducted before and after exercise during 3 months...
May 16, 2018: Sangyō Eiseigaku Zasshi, Journal of Occupational Health
https://www.readbyqxmd.com/read/29759615/enhancing-response-in-the-cardiac-resynchronization-therapy-patient-the-3b-perspective-bench-bits-and-bedside
#9
REVIEW
Angelo Auricchio, Frits W Prinzen
Cardiac resynchronization therapy (CRT) is an established nonpharmacological treatment for patients with heart failure (HF), reduced left ventricular (LV) ejection fraction, and a wide QRS complex. Although the therapy was developed 30 years ago and approved by the Food and Drug Administration in 2001, attempts to improve it have never stopped. Such improvements have been facilitated by combining knowledge from bench (basic science), bits (computer modeling), and bedside (clinical studies); these issues are addressed in the present review...
November 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29756612/cancer-of-the-head-and-neck-a-set-of-indicators-based-on-register-and-administrative-data
#10
A Andreano, M Ansarin, D Alterio, R Bruschini, M G Valsecchi, A G Russo
Head and neck (H&N) tumours are a heterogeneous group of neoplasms with 5-year relative survival ranging from about 25% for the hypopharynx to 60% for the larynx in Europe. To improve survival rates, along with therapeutic improvements, it is important to standardise and optimise care received by patients with H&N tumours across different healthcare providers. To reach this goal, it is necessary to evaluate adherence to standards of received care at a population level. Published guidelines can serve as the basis to develop indicators, which can be computed from administrative health databases, measuring the adherence to specific recommendations at the individual level in unselected H&N cancer patients, identified from a population cancer register...
February 2018: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/29724235/how-can-the-use-of-data-within-the-immunisation-programme-be-increased-in-order-to-improve-data-quality-and-ensure-greater-accountability-in-the-health-system-a-protocol-for-implementation-science-study
#11
Binyam Tilahun, Alemayehu Teklu, Arielle Mancuso, Zeleke Abebaw, Kassahun Dessie, Desalegn Zegeye
BACKGROUND: Immunisation remains one of the most important and cost-effective interventions to reduce vaccine-preventable child morbidity, disability and mortality. Health programmes like the Expanded Program of Immunization rely on complex decision-making and strong local level evidence is important to effectively and efficiently utilise limited resources. Lack of data use for decision-making at each level of the health system remains the main challenge in most developing countries. While there is much evidence on data quality and how to improve it, there is a lack of sufficient evidence on why the use of data for decision-making at each level of the health system is low...
May 3, 2018: Health Research Policy and Systems
https://www.readbyqxmd.com/read/29722555/exploring-health-services-accessibility-by-indigenous-women-in-asia-and-identifying-actions-to-improve-it-a-scoping-review
#12
Onouma Thummapol, Tanya Park, Sylvia Barton
OBJECTIVES: The aim of this scoping review was to uncover and summarize what is known in the literature about the experiences of Indigenous women in Asia regarding access to health services. DESIGN: The study was informed by the scoping review methodology proposed by Arksey and O'Malley [2005. "Scoping Studies: Towards a Methodological Framework." International Journal of Social Research Methodology 8 (1): 19-32. doi: 10.1080/1364557032000119616 ]. A comprehensive search of the databases for peer-reviewed studies and grey literature was conducted between January 2000 and December 2016...
May 3, 2018: Ethnicity & Health
https://www.readbyqxmd.com/read/29721291/our-use-misuse-and-abandonment-of-a-concept-whither-habitat
#13
David Anthony Kirk, Allysia C Park, Adam C Smith, Briar J Howes, Brigid K Prouse, Naschelly G Kyssa, Elizabeth N Fairhurst, Kent A Prior
The foundational concept of habitat lies at the very root of the entire science of ecology, but inaccurate use of the term compromises scientific rigor and communication among scientists and nonscientists. In 1997, Hall, Krausman & Morrison showed that 'habitat' was used correctly in only 55% of articles. We ask whether use of the term has been more accurate since their plea for standardization and whether use varies across the broader range of journals and taxa in the contemporary literature (1998-2012)...
April 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29708088/nutrition-and-public-health-in-medical-education-in-the-uk-reflections-and-next-steps
#14
Jonathan Broad, Megan Wallace
OBJECTIVE: Doctors play an important role in the identification of nutritional disorders and as advocates for a healthy diet, and although the key tenets of good nutrition education for medical students have been discussed, reports on implementation are sparse. The present commentary responds to a gap in UK medical students' understanding of nutrition and public health and suggests ways to improve it. DESIGN: We review literature about nutrition education in medical schools and discuss a 6-week elective in public health nutrition for medical students...
April 30, 2018: Public Health Nutrition
https://www.readbyqxmd.com/read/29707029/cardiac-myosin-activators-for-heart-failure-therapy-focus-on-omecamtiv-mecarbil
#15
REVIEW
Edgardo Kaplinsky, Gordon Mallarkey
Heart failure continues to be a major global health problem with a pronounced impact on morbidity and mortality and very limited drug treatment options especially with regard to inotropic therapy. Omecamtiv mecarbil is a first-in-class cardiac myosin activator, which increases the proportion of myosin heads that are tightly bound to actin and creates a force-producing state that is not associated with cytosolic calcium accumulation. Phase I and phase II studies have shown that it is safe and well tolerated...
2018: Drugs in Context
https://www.readbyqxmd.com/read/29696385/effects-of-different-weight-loss-approaches-on-cvd-risk
#16
REVIEW
Peter M Clifton, Jennifer B Keogh
PURPOSE OF REVIEW: In this review, we aimed to answer the question as to whether deliberate weight loss can reduce cardiovascular events or improve cardiovascular risk factors and whether different methods of weight loss can have a differential effect on risk factor improvement. RECENT FINDINGS: It would appear that deliberate weight loss reduces total mortality by 16% in obese people with risk factors including type 2 diabetes. People with type 2 diabetes who lose at least 10% of their initial body weight reduce CVD end points by 21% with dietary weight loss while the effect is greater with the greater weight loss induced by bariatric surgery with a 32% reduction in events...
April 25, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29686820/biofeedback-efficacy-to-improve-clinical-symptoms-and-endoscopic-signs-of-solitary-rectal-ulcer-syndrome
#17
Mojgan Forootan, Masood Shekarchizadeh, Hamedreza Farmanara, Ahmad Reza Shekarchizadeh Esfahani, Mansooreh Shekarchizadeh Esfahani
Solitary rectal ulcer syndrome (SRUS) is often resistant to medical and surgical treatment. This study assessed the effect of biofeedback in decreasing the symptoms and the healing of endoscopic signs in SRUS patients. Before starting the treatment, endoscopy and colorectal manometry was performed to evaluate dyssynergic defecation. Patients were followed every four weeks, and during each visit their response to treatment was evaluated regarding to manometry pattern. After at least 50% improvement in manometry parameters, recipients underwent rectosigmoidoscopy...
January 12, 2018: European Journal of Translational Myology
https://www.readbyqxmd.com/read/29682268/polysonographical-evaluation-in-a-case-of-moderate-osas-treated-with-mandibular-advancement-device
#18
A Venditti, M Basili, F M Ragazzoni, A Barlattani, P Bollero
Background: The Obstructive Sleep Apnea Syndrome (OSAS) is a clinical picture characterized by partial or complete obstruction of the upper airway during sleep, associated with a reduction of oxygen saturation in the blood.The most common symptoms are: apnea sleep, snoring, headache, sleepiness, reduced concentration and memory, irritability, increased blood pressure and dry mouth. Materials and methods: It was examinated a not-smoker man of 54 years that suffers of roncophaty...
October 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29680979/phencyclidine-and-scopolamine-for-modeling-amnesia-in-rodents-direct-comparison-with-the-use-of-barnes-maze-test-and-contextual-fear-conditioning-test-in-mice
#19
Natalia Malikowska-Racia, Adrian Podkowa, Kinga Sałat
Nowadays cognitive impairments are a growing unresolved medical issue which may accompany many diseases and therapies, furthermore, numerous researchers investigate various neurobiological aspects of human memory to find possible ways to improve it. Until any other method is discovered, in vivo studies remain the only available tool for memory evaluation. At first, researchers need to choose a model of amnesia which may strongly influence observed results. Thereby a deeper insight into a model itself may increase the quality and reliability of results...
April 21, 2018: Neurotoxicity Research
https://www.readbyqxmd.com/read/29673698/-which-information-is-given-during-the-purchase-of-an-hiv-self-test-in-a-caen-pharmacy-a-comprehensive-transversal-and-observational-study-using-surveys-without-modification-of-practice
#20
S Guitton, A Rabiaza
INTRODUCTION: HIV infection affects about 150,000 people in France. In total, 30,000 of them are unaware of their serostatus. In this context, HIV self-testing has arrived in France in September 2015. The aim of our study was to analyze the level of application of the recommendations during the purchase of an HIV self-test. Our primary hypothesis was that the delivered information is poor. METHODS: We realized a comprehensive transversal and observational study with surveys without modification of practice in all Caen pharmacies...
April 16, 2018: Annales Pharmaceutiques Françaises
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