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https://www.readbyqxmd.com/read/28646394/the-antihypertensive-efficacy-of-the-triple-fixed-combination-of-perindopril-indapamide-and-amlodipine-the-results-of-the-petra-study
#1
György Ábrahám, Csaba András Dézsi
INTRODUCTION: The etiology of essential hypertension is multifactorial. Therefore, treatment with combinations of antihypertensive agents acting on multiple targets is necessary for successful therapy in the majority of patients. According to the experience and clinical data accumulated so far, combination therapy with three agents from different pharmacological classes is required in approx. 30% of patients in order to achieve long-term blood pressure control. The primary objective of the PETRA study was to evaluate the efficacy of blood pressure (BP) control with once daily administration of the different dosage strengths of the once-daily, triple fixed combination of perindopril, indapamide, and amlodipine...
June 23, 2017: Advances in Therapy
https://www.readbyqxmd.com/read/28645716/guide-to-active-vaccine-safety-surveillance-report-of-cioms-working-group-on-vaccine-safety-executive-summary
#2
U Heininger, K Holm, I Caplanusi, S R Bailey
In 2013, the Council for International Organizations of Medical Sciences (CIOMS) created a Working Group on Vaccine Safety (WG) to address unmet needs in the area of vaccine pharmacovigilance. Generating reliable data about specific vaccine safety concerns is becoming a priority due to recent progress in the development and deployment of new vaccines of global importance, as well as novel vaccines targeting diseases specifically endemic to many resource-limited countries (RLCs), e.g. malaria, dengue. The WG created a Guide to Active Vaccine Safety Surveillance (AVSS) to assist national regulatory authorities and national immunization program officers in RLCs in determining the best course of action with regards to non-routine pharmacovigilance activities, when confronted with a launch of a new vaccine or a vaccine that is new to their country...
June 20, 2017: Vaccine
https://www.readbyqxmd.com/read/28645218/wide-awake-anesthesia-in-the-in-office-procedure-room-lessons-learned
#3
Robert E Van Demark, Hillary A Becker, Matthew C Anderson, Vanessa J S Smith
BACKGROUND: Wide-awake local anesthesia and no tourniquet (WALANT) has become more popular in hand surgery. Without a tourniquet, there is no need for preoperative testing or sedation. The use of lidocaine with epinephrine has allowed a larger variety of cases to be done safely in an outpatient setting instead of the hospital. "Minor field sterility," which uses fewer drapes and tools to accomplish the same procedures, is a concept that is also gaining recognition. METHODS: Investigation of hand surgeons performing a majority of cases using WALANT and minor field sterility was the beginning of seeing its potential at our institution...
June 1, 2017: Hand: Official Journal of the American Association for Hand Surgery
https://www.readbyqxmd.com/read/28644335/practice-bulletin-number-179-breast-cancer-risk-assessment-and-screening-in-average-risk-women
#4
(no author information available yet)
Breast cancer is the most commonly diagnosed cancer in women in the United States and the second leading cause of cancer death in American women (1). Regular screening mammography starting at age 40 years reduces breast cancer mortality in average-risk women (2). Screening, however, also exposes women to harm through false-positive test results and overdiagnosis of biologically indolent lesions. Differences in balancing benefits and harms have led to differences among major guidelines about what age to start, what age to stop, and how frequently to recommend mammography screening in average-risk women (2-4)...
July 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28644328/practice-bulletin-no-179-summary-breast-cancer-risk-assessment-and-screening-in-average-risk-women
#5
(no author information available yet)
Breast cancer is the most commonly diagnosed cancer in women in the United States and the second leading cause of cancer death in American women (1). Regular screening mammography starting at age 40 years reduces breast cancer mortality in average-risk women (2). Screening, however, also exposes women to harm through false-positive test results and overdiagnosis of biologically indolent lesions. Differences in balancing benefits and harms have led to differences among major guidelines about what age to start, what age to stop, and how frequently to recommend mammography screening in average-risk women (2-4)...
July 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28643658/quality-assessment-of-pelvic-ultrasound-for-uterine-myoma-according-to-the-cngof-guidelines
#6
D Perrot, H Fernandez, J M Levaillant, P Capmas
INTRODUCTION: French guidelines regarding the minimum criteria for gynaecological ultrasound were given in a recent report in 2016, by the French National College of Obstetricians and Gynaecologists (CNGOF). An accurate report is essential for the optimal care of women, especially those presenting myomas. The goal of this study was to evaluate the quality of gynaecological ultrasound reports for women with type 0 to 2 uterine myomas, referring to the items contained in the French guidelines...
April 2017: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/28642642/access-to-and-payment-for-office-based-buprenorphine-treatment-in-ohio
#7
Theodore V Parran, Joseph Z Muller, Elina Chernyak, Chris Adelman, Christina M Delos Reyes, Douglas Rowland, Mykola Kolganov
IMPORTANCE: Office-based opiate agonist therapy has dramatically expanded access to medication-assisted treatment over the past decade but has also led to increased buprenorphine diversion. OBJECTIVE: Our study sought to characterize physicians who participate in office-based therapy (OBT) to assess patient access to OBT in Ohio 10 years after its introduction. DESIGN/SETTING/PARTICIPANTS: Cross-sectional telephone survey of Drug Addiction Treatment Act-waivered physicians in Ohio listed by the Center for Substance Abuse Treatment (CSAT)...
2017: Substance Abuse: Research and Treatment
https://www.readbyqxmd.com/read/28641954/interventional-rheumatology-the-competence-of-brazilian-rheumatologists
#8
Aline Teixeira de Landa, Jamil Natour, Rita Nely Vilar Furtado
OBJECTIVES: Describe Brazilian rheumatologists's competence in interventional rheumatology; assess the association between this ability and demographic and training variables. METHODS: A cross-sectional study with 500 Brazilian rheumatologists. Participants were assessed by self-administered questionnaire consisting of demographics, training, practice in office and knowledge in interventional rheumatology data. RESULTS: 463 participants had their data analyzed...
June 19, 2017: Revista Brasileira de Reumatologia
https://www.readbyqxmd.com/read/28636506/incidence-and-predictors-of-atrial-fibrillation-after-coronary-artery-bypass-surgery-detection-by-event-loop-recorder-monitoring-from-a-contemporary-multicentre-cohort
#9
Zainab Abdel-Salam, Wail Nammas
Background Atrial fibrillation (AF) is a frequent complication after cardiac surgery. We explored the incidence and predictors of post-operative AF at 30-day follow-up in an unselected multi-centre cohort of patients undergoing elective coronary artery bypass grafting (CABG) in contemporary practice. Methods and results We enrolled 740 consecutive patients scheduled for elective CABG with or without valve surgery. Cardiac rhythm was continuously monitored for 15 days after surgery by an ambulatory event loop recorder...
March 21, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28636180/characterization-of-herpes-simplex-virus-infections-seen-in-the-pediatric-dermatology-office
#10
Julia K Gittler, Euphemia W Mu, Seth J Orlow
BACKGROUND/OBJECTIVES: Atypical and severe clinical manifestations of primary and recurrent herpes simplex virus (HSV) infections may present to a pediatric dermatologist for evaluation. The purpose of this study was to characterize the clinical features of the population diagnosed with HSV referred to a pediatric dermatology office. METHODS: This retrospective case series examined patients diagnosed with HSV in a pediatric dermatology practice at an academic medical center from 2005 to 2015...
June 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28632856/the-patent-laws-and-patent-office-practice
#11
(no author information available yet)
No abstract text is available yet for this article.
June 20, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28629463/how-understanding-and-application-of-drug-related-legal-instruments-affects-harm-reduction-interventions-in-cambodia-a-qualitative-study
#12
Sovannary Tuot, Chanrith Ngin, Khuondyla Pal, Sochenda Sou, Ghazal Sawez, Phylicia Morgan, Mony Srey, Tola Chan, Pheak Chhoun, Olga Golichenko, Sok Chamreun Choub, Siyan Yi
BACKGROUND: Harm reduction interventions in Cambodia face numerous obstacles because of conflicting understanding and interests and inconsistencies in the implementation by law enforcement officials. This study aims to examine how understanding and application of Drug Control Law (DCL) and Village/Commune Safety Policy (VCSP) affects harm reduction interventions in Cambodia from the standpoints of law enforcement officials, people who inject drugs and people who use drugs (PWID/PWUD), as well as other key stakeholders...
June 19, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28623995/rationale-design-and-methodology-of-the-observational-insights-svt-study-on-the-current-state-of-care-and-outcomes-of-patients-with-superficial-vein-thrombosis
#13
Rupert Bauersachs, Horst Eberhard Gerlach, Andreas Heinken, Ulrich Hoffmann, Florian Langer, Thomas Noppeney, David Pittrow, Jens Klotsche, Eberhard Rabe
OBJECTIVE: Superficial vein thrombosis (SVT) is a common disease in clinical practice. In terms of pathophysiology and outcomes, the condition is related to venous thromboembolism, bearing a potential for severe thromboembolic complications if it is not treated adequately. A wide range of treatment approaches (including oral and injectable anticoagulants, pain medication, nondrug therapy including compression therapy, and no treatment at all) are applied in clinical practice, but there is sparse information about selection of patients for therapies, current treatment pathways, and drug use as well as outcomes...
July 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28622314/development-of-a-simple-computerized-torsion-test-to-quantify-subjective-ocular-torsion
#14
Y D Kim, H K Yang, J-M Hwang
PurposeThe double Maddox-rod test (DMRT) and Lancaster red-green test (LRGT) are the most widely used tests worldwide to assess subjective ocular torsion. However, these tests require equipment and the quantified results of ocular torsion are only provided in rough values. Here we developed a novel computerized torsion test (CTT) for individual assessment of subjective ocular torsion and validated the reliability and accuracy of the test compared with those of the DMRT and LRGT.MethodsA total of 30 patients with cyclovertical strabismus and 30 controls were recruited...
June 16, 2017: Eye
https://www.readbyqxmd.com/read/28621808/primary-care-interventions-to-reduce-childhood-obesity-and-sugar-sweetened-beverage-consumption-food-for-thought-for-oral-health-professionals
#15
Diane Dooley, Nicolette M Moultrie, Elsbeth Sites, Patricia B Crawford
OBJECTIVES: Childhood obesity remains a significant threat to America's children. Health care leaders have increasingly called upon oral health professionals to integrate healthy weight promotion and enhanced sugar-sweetened beverage counseling into their professional practices. The aim of this scoping review is to examine recent evidence regarding the effectiveness of primary care childhood obesity interventions that have potential for adoption by oral health professionals. METHODS: Medine, and PubMed were searched from 2010 to 2016 for review articles and studies reporting patient outcomes or policy outcomes relevant to primary care childhood obesity interventions for children ages 2-11 years...
June 16, 2017: Journal of Public Health Dentistry
https://www.readbyqxmd.com/read/28617194/impact-of-online-toxicology-training-on-health-professionals-the-global-educational-toxicology-uniting-project-getup
#16
Anselm Wong, Rais Vohra, Andrew H Dawson, Andrew Stolbach
OBJECTIVE: The Global Educational Toxicology Uniting Project (GETUP), supported by the American College of Medical Toxicology, links countries with and without toxicology services via distance education with the aim to improve education. Due to the lack of toxicology services in some countries there is a knowledge gap in the management of poisonings. We describe our experience with the worldwide delivery of an online introductory toxicology curriculum to emergency doctors and other health professionals treating poisoned patients...
June 15, 2017: Clinical Toxicology
https://www.readbyqxmd.com/read/28617122/how-to-make-a-career-in-emergency-nursing
#17
Frances Cannon, Linsey Sheerin, Roisin Devlin
The Professional Framework for Emergency Care Nursing was officially launched at the Northern Ireland Practice and Education Council (NIPEC) annual conference in March. It was born from chief nursing officer Charlotte McArdle asking NIPEC to collaborate with the local RCN emergency care network to further the professional development of the emergency nursing workforce in Northern Ireland.
June 15, 2017: Emergency Nurse: the Journal of the RCN Accident and Emergency Nursing Association
https://www.readbyqxmd.com/read/28616486/goat-farm-management-and-brucella-serological-test-among-goat-keepers-and-livestock-officers-2011-2012-nakhon-si-thammarat-province-southern-thailand
#18
Thanidtha Te-Chaniyom, Alan F Geater, Wandee Kongkaew, Usa Chethanond, Virasakdi Chongsuvivatwong
Brucellosis, a zoonotic disease particularly affecting goats, emerged in Thailand in 2003, resulting in both an occupational hazard for goat keepers and livestock officers, and production losses. Farm management practices have been identified as risk factors associated with Brucella sero-positivity in many studies. Our finding in this study should be considered in order to strengthen the system of biosecurity control in farm animals as one health approach. The objectives of the study were to describe the distribution of potential risk factors by types of goat farms and to document the prevalence of human Brucella sero-positivity among goat keepers and livestock officers in Nakhon Si Thammarat, Thailand...
December 2016: One Health
https://www.readbyqxmd.com/read/28615468/in-pursuit-of-the-evidence-a-short-biography-of-paul-c-schreckenberger-ph-d
#19
Karen C Carroll
On a bookshelf in my office, next to the Manual of Clinical Microbiology, still sits a dog-eared copy of a pamphlet entitled "Practical Approach to the Identification of Glucose-Nonfermenting Gram-negative Bacilli, a Guide to Identification" authored by Paul C Schreckenberger, Ph.D (1).….
June 14, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28614231/incidence-prevalence-and-natural-history-of-primary-sclerosing-cholangitis-in-the-united-kingdom
#20
Huifang Liang, Sudhakar Manne, Jesse Shick, Trevor Lissoos, Paul Dolin
Primary sclerosing cholangitis (PSC) is a rare obliterative fibrotic condition of the bile ducts. We assessed PSC epidemiology and natural history within the UK Clinical Practice Research Datalink (CPRD).Incidence and natural history of PSC were evaluated in a retrospective cohort study using linkage of CPRD, Hospital Episode Statistics, and Office for National Statistics data. Data from age, sex, and general practice-matched population controls provided a context for the incident PSC patients. Liver disease other than PSC was defined as autoimmune hepatitis, hepatitis, hepatomegaly, liver failure, cirrhosis, portal hypertension, cholangiocarcinoma, or hepatobiliary cancer...
June 2017: Medicine (Baltimore)
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