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https://www.readbyqxmd.com/read/29232663/serum-leptin-resistin-and-adiponectin-concentrations-in-psoriasis-a-meta-analysis-of-observational-studies
#1
Aikaterini Kyriakou, Aikaterini Patsatsi, Dimitrios Sotiriadis, Dimitrios G Goulis
BACKGROUND: Psoriasis is an immune-mediated, inflammatory disease. Adipokines contribute to the regulation of immune-mediated processes and inflammation. OBJECTIVE: The aim of our study was to systematically review the literature for studies that have evaluated the circulating concentrations of adipokines in patients with psoriasis and controls and to meta-analyze the best evidence available. METHODS: Eligible were studies that have assessed leptin, resistin, or adiponectin concentrations in psoriatic patients and a reference group...
December 13, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29232658/a-meta-analysis-of-randomized-controlled-trials-on-the-use-of-suction-drains-following-rectal-surgery
#2
Francesco Guerra, Giuseppe Giuliani, Diego Coletta, Marcello Boni, Fabio Rondelli, Paolo Pietro Bianchi, Andrea Coratti
BACKGROUND: Anastomotic leakage is one of the most feared complications of rectal resections. The role of drains in limiting this occurrence or facilitating its early recognition is still poorly defined. We aimed to study whether the presence of prophylactic pelvic drains affects the surgical outcomes of patients undergoing rectal surgery with extraperitoneal anastomosis. METHODS: PubMed, EMBASE, and the Cochrane Library were systematically searched for randomized controlled trials comparing drained with undrained anastomoses following rectal surgery...
December 12, 2017: Digestive Surgery
https://www.readbyqxmd.com/read/29232491/anhedonia-is-associated-with-suicidal-ideation-independently-of-depression-a-meta-analysis
#3
Déborah Ducasse, Gwenolé Loas, Déborah Dassa, Carla Gramaglia, Patrizia Zeppegno, Sébastien Guillaume, Emilie Olié, Philippe Courtet
BACKGROUND: Anhedonia is considered a suicide risk factor in patients with major affective disorders. Here, we wanted to quantify the association between anhedonia and current suicidal ideation according to the absence/presence of between-group differences for depressive scores and psychiatric disorders. METHODS: We performed a meta-analysis of data on studies retrieved from Medline, Web of Science, and PsycINFO from 1965 to 2016 using, among others, the terms (suicid* or depression) and anhedonia...
December 12, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/29232439/body-mass-index-and-breast-cancer-survival-a-mendelian-randomization-analysis
#4
Qi Guo, Stephen Burgess, Constance Turman, Manjeet K Bolla, Qin Wang, Michael Lush, Jean Abraham, Kristiina Aittomäki, Irene L Andrulis, Carmel Apicella, Volker Arndt, Myrto Barrdahl, Javier Benitez, Christine D Berg, Carl Blomqvist, Stig E Bojesen, Bernardo Bonanni, Judith S Brand, Hermann Brenner, Annegien Broeks, Barbara Burwinkel, Carlos Caldas, Daniele Campa, Federico Canzian, Jenny Chang-Claude, Stephen J Chanock, Suet-Feung Chin, Fergus J Couch, Angela Cox, Simon S Cross, Cezary Cybulski, Kamila Czene, Hatef Darabi, Peter Devilee, W Ryan Diver, Alison M Dunning, Helena M Earl, Diana M Eccles, Arif B Ekici, Mikael Eriksson, D Gareth Evans, Peter A Fasching, Jonine Figueroa, Dieter Flesch-Janys, Henrik Flyger, Susan M Gapstur, Mia M Gaudet, Graham G Giles, Gord Glendon, Mervi Grip, Jacek Gronwald, Lothar Haeberle, Christopher A Haiman, Per Hall, Ute Hamann, Susan Hankinson, Jaana M Hartikainen, Alexander Hein, Louise Hiller, Frans B Hogervorst, Bernd Holleczek, Maartje J Hooning, Robert N Hoover, Keith Humphreys, David J Hunter, Anika Hüsing, Anna Jakubowska, Arja Jukkola-Vuorinen, Rudolf Kaaks, Maria Kabisch, Vesa Kataja, Julia A Knight, Linetta B Koppert, Veli-Matti Kosma, Vessela N Kristensen, Diether Lambrechts, Loic Le Marchand, Jingmei Li, Annika Lindblom, Sara Lindström, Jolanta Lissowska, Jan Lubinski, Mitchell J Machiela, Arto Mannermaa, Siranoush Manoukian, Sara Margolin, Federik Marme, John W M Martens, Catriona McLean, Primitiva Menéndez, Roger L Milne, Anna Marie Mulligan, Taru A Muranen, Heli Nevanlinna, Patrick Neven, Sune F Nielsen, Børge G Nordestgaard, Janet E Olson, Jose I A Perez, Paolo Peterlongo, Kelly-Anne Phillips, Christopher J Poole, Katri Pylkäs, Paolo Radice, Nazneen Rahman, Thomas Rüdiger, Anja Rudolph, Elinor J Sawyer, Fredrick Schumacher, Petra Seibold, Caroline Seynaeve, Mitul Shah, Ann Smeets, Melissa C Southey, Rob A E M Tollenaar, Ian Tomlinson, Helen Tsimiklis, Hans-Ulrich Ulmer, Celine Vachon, Ans M W van den Ouweland, Laura J Van't Veer, Hans Wildiers, Walter Willett, Robert Winqvist, M Pilar Zamora, Georgia Chenevix-Trench, Thilo Dörk, Douglas F Easton, Montserrat García-Closas, Peter Kraft, John L Hopper, Wei Zheng, Marjanka K Schmidt, Paul D P Pharoah
Background: There is increasing evidence that elevated body mass index (BMI) is associated with reduced survival for women with breast cancer. However, the underlying reasons remain unclear. We conducted a Mendelian randomization analysis to investigate a possible causal role of BMI in survival from breast cancer. Methods: We used individual-level data from six large breast cancer case-cohorts including a total of 36 210 individuals (2475 events) of European ancestry...
December 1, 2017: International Journal of Epidemiology
https://www.readbyqxmd.com/read/29232378/genetic-variations-at-8q24-and-gastric-cancer-susceptibility-a-meta-analysis-study
#5
Pengke Zhi, Jian Shi, Feng Liu
BACKGROUND: Published data on the association between genetic variants on the 8q24 chromosome and gastric cancer (GC) susceptibility are inconclusive. Here we present a meta-analysis designed to evaluate the relationship between 8q24 variants (single nucleotide polymorphisms (SNPs) labeled rs6983267 and rs1447295) and risk of developing GC. METHODS: A literature search was performed using studies published on PubMed, Science Direct, OVID and Web of Science databases up to December 2016...
2017: PloS One
https://www.readbyqxmd.com/read/29232341/evidence-based-management-of-drains-following-pancreatic-resection-a-systematic-review
#6
Nicole Villafane-Ferriol, Rohan M Shah, Somala Mohammed, George Van Buren, Omar Barakat, Nader N Massarweh, Hop S Tran Cao, Eric J Silberfein, Cary Hsu, William E Fisher
Many pancreatic surgeons continue to use intraperitoneal drains, but others have limited or avoided their use, believing this improves outcomes. We conducted a systematic review and meta-analysis of the literature assessing outcomes in pancreatectomy without drains, selective drainage, and early drain removal. We searched PubMed, Embase, and the Cochrane Library databases and conducted a systematic review of randomized and nonrandomized studies comparing routine intra-abdominal drainage versus no drainage, selective drain use, and early versus late drain removal after pancreatectomy, with major complications as the primary outcome...
January 2018: Pancreas
https://www.readbyqxmd.com/read/29232307/outcome-measure-scores-predict-discharge-destination-in-patients-with-acute-and-subacute-stroke-a-systematic-review-and-series-of-meta-analyses
#7
Emily R Thorpe, Katie B Garrett, Ashley M Smith, Jennifer C Reneker, Robert S Phillips
BACKGROUND AND PURPOSE: To identify the association between outcome measure score and discharge destination in adults following acute or subacute stroke in the United States. METHODS: A systematic literature search was performed in 3 databases using the PRISMA guidelines. Cohort studies were selected that included patients with acute or subacute stroke, which explored the relationship between scores on outcome measures and discharge destination. Four meta-analyses were performed...
January 2018: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/29232294/the-need-for-consistent-predictors-of-success-for-surgical-ablation-of-atrial-fibrillation-a-call-to-action
#8
Niv Ad, Sari Diana Holmes, Jay Patel, Hyung Gon Je, Deborah J Shuman
OBJECTIVE: As with any medical therapy, identification of consistent and reliable outcome predictors is essential to understanding the efficacy of surgical ablation for atrial fibrillation. We originally intended to conduct a meta-analysis on atrial fibrillation surgical ablation to identify clinical factors that are most often associated with success. However, these studies are greatly heterogeneous. We conducted a systematic review to identify trends in outcome predictors and to provide recommendations for more uniform data analysis and reporting...
December 7, 2017: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/29232280/accuracy-of-self-reported-hypertension-a-systematic-review-and-meta-analysis
#9
Vivian S S Gonçalves, Keitty R C Andrade, Kenia M B Carvalho, Marcus T Silva, Mauricio G Pereira, Tais F Galvao
OBJECTIVE: To estimate the sensitivity and specificity of self-reported hypertension (HTN) as compared with the clinical diagnosis in epidemiological studies. METHODS: We searched MEDLINE, Embase, Scopus, Web of Science, LILACS, Google Scholar, and ProQuest Dissertations & Theses Global: Health & Medicine databases. In addition, we screened the references' lists of relevant reports to identify potentially eligible articles. There were no date or language restrictions...
December 11, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/29232265/the-value-of-preoperative-exercise-and-education-for-patients-undergoing-total-hip-and-knee-arthroplasty-a-systematic-review-and-meta-analysis
#10
Rebecca Moyer, Kathy Ikert, Kristin Long, Jacquelyn Marsh
BACKGROUND: Existing evidence regarding the value of preoperative education and/or exercise (prehabilitation) for patients undergoing total joint replacement is conflicting. The purpose of this study was to conduct an updated, comprehensive systematic review with meta-analyses to determine the longitudinal effects and efficacy of prehabilitation on postoperative outcomes in patients undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA). METHODS: We searched 11 electronic databases (MEDLINE, AMED, CINAHL, Embase, Scopus, ProQuest, PEDro, SportDiscus, PsycINFO, and Cochrane) from their inception to May 2016 for randomized controlled trials that compared changes in pain, function, strength, anxiety, and hospital length of stay following THA or TKA...
December 12, 2017: JBJS Reviews
https://www.readbyqxmd.com/read/29232250/results-of-a-second-examination-of-the-right-side-of-the-colon-in-screening-and-surveillance-colonoscopy-a-systematic-review-and-meta-analysis
#11
Xiuyun Ai, Weiguang Qiao, Zemin Han, Wenxin Tan, Yang Bai, Side Liu, Fachao Zhi
BACKGROUND: Screening colonoscopy is less effective in preventing proximal colon cancers than distal colon cancers. A repeat examination of the right side of the colon may increase the lesion detection. The study aimed to assess the results of a second examination of the right side of the colon with forward-view or retroflexion colonoscopy performed immediately after the initial examination. MATERIALS AND METHODS: We carried out a meta-analysis of all primary studies that performed a second examination of the right side of the colon with forward-view or retroflexion colonoscopy performed immediately after the initial examination...
December 11, 2017: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29232047/antibiotic-prophylaxis-in-ureteroscopic-lithotripsy-a%C3%A2-systematic-review-and-meta-analysis-of-comparative-studies
#12
Tuo Deng, Bing Liu, Xiaolu Duan, Chao Cai, Zhijian Zhao, Wei Zhu, Junhong Fan, Wenqi Wu, Guohua Zeng
OBJECTIVE: To explore the efficacy and detailed strategies of antibiotic prophylaxis in ureteroscopic lithotripsy (URL) through a systematic review and meta-analysis. MATERIALS AND METHODS: A systematic literature search using Pubmed, Embase, Medline, Cochrane Library, CBM, CNKI and VIP databases was performed to obtain comparative studies on the efficacy of different antibiotic prophylaxis strategies in URL for preventing postoperative infections. The last search was conducted on June 25, 2017...
December 12, 2017: BJU International
https://www.readbyqxmd.com/read/29232046/male-circumcision-for-the-prevention-of-hiv-acquisition-a-meta-analysis
#13
REVIEW
Sanjeev C Sharma, Nicholas Raison, Shamim Khan, Majid Shabbir, Prokar Dasgupta, Kamran Ahmed
OBJECTIVES: To assess male circumcision for the prevention of HIV acquisition in heterosexual and homosexual men using all available data. Previous meta-analyses suggest that circumcision is effective at reducing the risk of HIV acquisition amongst heterosexual men but the effect amongst homosexual males remains under debate. SUBJECTS AND METHODS: A systematic literature review was conducted searching for studies that assessed male circumcision as a method to prevent HIV acquisition in homosexual and/or heterosexual males...
December 12, 2017: BJU International
https://www.readbyqxmd.com/read/29232031/systematic-review-and-meta-analysis-of-reported-adverse-events-of-long-term-intranasal-oxytocin-treatment-for-autism-spectrum-disorder
#14
REVIEW
Qizheng Cai, Lei Feng, Kai Zhen Yap
Recent studies suggested oxytocin as a possible drug to treat social deficits caused by Autism Spectrum Disorder (ASD), but the safety of intranasal oxytocin in autistic patients is not established. The aim of this review was to characterise the side effect profile of long-term intranasal oxytocin in treatment of ASD compared to placebo. All randomised controlled trials of intranasal oxytocin in the treatment of ASD published before 1 January 2017 that reported safety data were identified from databases including Pubmed, Embase, Cochrane Library, and International Pharmaceutical Abstract...
December 12, 2017: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29231125/attentional-focus-and-grip-width-influences-on-bench-press-resistance-training
#15
Joaquin Calatayud, Jonas Vinstrup, Markus D Jakobsen, Emil Sundstrup, Juan Carlos Colado, Lars L Andersen
This study evaluated the influence of different attentional foci for varied grip widths in the bench press. Eighteen resistance-trained men were familiarized with the procedure and performed a one-repetition maximum (1RM) test during Session 1. In Session 2, they used three different standardized grip widths (100%, 150%, and 200% of biacromial width distance) in random order at 50% of 1RM while also engaged in three different attention focus conditions (external focus on the bench press, internal focus on pectoralis major muscles, and internal focus on triceps brachii muscles)...
January 1, 2017: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29231068/clinicopathological-and-prognostic-significance-of-platelet-count-in-patients-with-ovarian-cancer
#16
Q Zhou, F Huang, Z He, M-Z Zuo
AIM: Increasing evidence indicates that platelet count is a useful biomarker of long-term outcomes in patients with ovarian cancer. However, the prognostic value of platelet count in patients with ovarian cancer remains controversial. We therefore conducted a meta-analysis aimed to investigate the prognostic role of the platelet count in patients with ovarian cancer. METHOD: A comprehensive search was performed from the databases of PubMed, Embase and the Cochrane Library until June 20, 2017...
December 12, 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/29231052/efficacy-and-safety-of-ranolazine-in-diabetic-patients-a-systematic-review-and-meta-analysis
#17
Xiaofang Zeng, Yinyin Zhang, Jianhui Lin, Haikuo Zheng, Jie Peng, Wei Huang
BACKGROUND: Recent studies have discovered that the antiangina agent ranolazine exerts a glucometabolic effect. OBJECTIVE: This systematic review and meta-analysis aimed to further understand the efficacy and safety profile of ranolazine in patients with diabetes. METHODS: Randomized controlled trials (RCTs) were searched in PubMed, Cochrane, and EMBASE databases and in ClinicalTrials.gov up to July 2017. Efficacy end points were defined as the change in hemoglobin A1C (A1C) and fasting serum glucose (FSG) levels...
December 1, 2017: Annals of Pharmacotherapy
https://www.readbyqxmd.com/read/29230866/utility-of-hba1c-and-fasting-plasma-glucose-for-screening-of-type-2-diabetes-a-meta-analysis-of-full-roc-curves
#18
A Hoyer, W Rathmann, O Kuss
AIMS: There is still debate on the optimal threshold for population-based screening of diabetes (diagnosed by the oral glucose tolerance test) using tests like HbA1c or fasting plasma glucose. Meta-analyses provide meaningful input in such situations. The aim of this article is to perform a meta-analysis that includes the complete information reported in the individual studies of two existing systematic reviews. METHODS: We screened the individual studies from two systematic reviews and reconstructed the full four-fold tables for every reported threshold...
December 12, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29230852/data-generating-models-of-dichotomous-outcomes-heterogeneity-in-simulation-studies-for-a-random-effects-meta-analysis
#19
Konstantinos Pateras, Stavros Nikolakopoulos, Kit Roes
Simulation studies to evaluate performance of statistical methods require a well-specified data-generating model. Details of these models are essential to interpret the results and arrive at proper conclusions. A case in point is random-effects meta-analysis of dichotomous outcomes. We reviewed a number of simulation studies that evaluated approximate normal models for meta-analysis of dichotomous outcomes, and we assessed the data-generating models that were used to generate events for a series of (heterogeneous) trials...
December 11, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/29230798/botulinum-toxin-type-a-therapy-for-cervical-dystonia
#20
REVIEW
Mafalda Castelão, Raquel E Marques, Gonçalo S Duarte, Filipe B Rodrigues, Joaquim Ferreira, Cristina Sampaio, Austen P Moore, João Costa
BACKGROUND: This is an update of a Cochrane Review first published in 2005. Cervical dystonia is the most common form of focal dystonia and is a highly disabling movement disorder characterised by involuntary, usually painful, head posturing. Currently, botulinum toxin type A (BtA) is considered the first line therapy for this condition. OBJECTIVES: To compare the efficacy, safety, and tolerability of botulinum toxin type A (BtA) versus placebo in people with cervical dystonia...
December 12, 2017: Cochrane Database of Systematic Reviews
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