keyword
MENU ▼
Read by QxMD icon Read
search

Synovitis

keyword
https://www.readbyqxmd.com/read/29667227/effects-of-knockout-of-the-receptor-for-advanced-glycation-end-products-on-bone-mineral-density-and-synovitis-in-mice-with-intra-articular-fractures
#1
Dongrim Seol, Yuki Tochigi, Ashley M Bogner, Ino Song, Douglas C Fredericks, Gail L Kurriger, Sonja M Smith, Jessica E Goetz, Joseph A Buckwalter, James A Martin
Our group employed the mouse closed intra-articular fracture (IAF) model to test the hypothesis that the innate immune system plays a role in initiating synovitis and post-traumatic osteoarthritis (PTOA) in fractured joints. A transgenic strategy featuring knockout of the receptor for advanced glycation end-products (RAGE -/- ) was pursued. The 42 and 84 mJ impacts used to create fractures were in the range previously reported to cause PTOA at 60 days post-fracture. MicroCT (µCT) was used to assess fracture patterns and epiphyseal and metaphyseal bone loss at 30 and 60 days post-fracture...
April 17, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29665800/mda-5-associated-rapidly-progressive-interstitial-lung-disease-with-recurrent-pneumothoraces-a-case-report
#2
Safi Alqatari, Peter Riddell, Sinead Harney, Michael Henry, Grainne Murphy
BACKGROUND: Clinically hypomyopathic dermatomyositis is a rare disease that is important to recognize, investigate and treat early as it is associated with poor prognosis. In a proportion of patients, myositis specific antibodies could be negative, but with high clinical suspicion, myositis associated antibodies should be ordered. Anti-MDA-5 antibodies was reported in literature to be associated with severe and rapidly progressive interstitial lung disease, with few case reports of pneumothorax and/or pneumomediastinum...
April 17, 2018: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/29663487/relationship-between-arthroscopic-findings-of-synovitis-and-levels-of-tumor-necrosis-factor-alpha-and-matrix-metalloproteinases-in-synovial-lavage-fluid-from-patients-with-unilateral-high-mandibular-condyle-fractures
#3
Shinnosuke Nogami, Tetsu Takahashi, Kensuke Yamauchi, Yuri Takeda, Ko Ito, Masatoshi Chiba, Alexander Gaggl
BACKGROUND: Arthrocentesis has an effect of washing out inflammatory products that accumulate in the joint compartment of a dysfunctional TMJ. The procedure removes inflammatory cytokines, which are pain-causing substances, for early reduction of TMJ pain and quick recovery of jaw function, thus increasing the possibility of a successful rehabilitation. OBJECTIVE: The aim of the present study was to investigate the relationship between arthroscopy synovitis grade in patients with unilateral high condylar fractures and concentrations of the pro-inflammatory cytokines tumor necrosis factor (TNF)-alpha as well as of matrix metalloproteinases (MMPs) in washed-out synovial fluid (SF) samples obtained from those patients...
April 16, 2018: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/29657833/paradoxical-arthritis-occurring-during-anti-tnf-in-patients-with-inflammatory-bowel-disease-histological-and-immunological-features-of-a-complex-synovitis
#4
Stefano Alivernini, Daniela Pugliese, Barbara Tolusso, Laura Bui, Luca Petricca, Luisa Guidi, Luisa Mirone, Gian Ludovico Rapaccini, Francesco Federico, Gianfranco Ferraccioli, Alessandro Armuzzi, Elisa Gremese
Objective: Paradoxical arthritis under tumour necrosis factor inhibitor (TNF-i) for inflammatory bowel disease (IBD) has been described. This study aims to evaluate the histological features of paired synovial tissue (ST) and colonic mucosa (CM) tissue in patients with IBD developing paradoxical arthritis under TNF-i. Methods: Patients with IBD without history of coexisting joint involvement who developed arthritis under TNF-i were enrolled. Each patient underwent ST biopsy and ileocolonoscopy with CM biopsies...
2018: RMD Open
https://www.readbyqxmd.com/read/29657139/power-doppler-ultrasound-evaluation-of-peripheral-joint-entheses-tendon-and-bursa-abnormalities-in-psoriatic-patients-a-clinical-study
#5
Yuanjiao Tang, Yujia Yang, Xi Xiang, Liyun Wang, Lingyan Zhang, Li Qiu
OBJECTIVE: To evaluate the prevalence rates of peripheral joint, enthesis, tendon, and bursa abnormalities by power Doppler (PD) ultrasonic examination in patients with psoriatic arthritis (PsA), psoriatic patients without clinical signs of arthritis (non-PsA psoriasis group), and healthy individuals, to detect subclinical PsA. METHODS: A total of 253 healthy volunteers, 242 non-PsA psoriatic patients, and 86 patients with PsA were assessed by 2-dimensional and power Doppler (PD) ultrasound...
April 15, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29644038/calcific-tendonitis-of-the-quadriceps-tendon
#6
S A Webb, M A Hopper, J Chitnavis
A 61-year-old woman presented with chronic anterior pain and stiffness in the distal left thigh. Examination revealed swelling and tenderness immediately proximal to the patella. Radiographs showed opacities in the distal anterior thigh whilst MRI identified enlargement of the distal quadriceps tendon with splayed fibres separated by solid conglomerates. Dystrophic calcification of the quadriceps tendon was diagnosed. Blood tests revealed no systemic abnormalities in calcium handling. Arthroscopy of the left knee identified calcific deposits in the supra-patella pouch with surrounding synovitis...
April 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29623147/chronic-pain-in-inflammatory-arthritis-mechanisms-metrology-and-emerging-targets-a-focus-on-the-jak-stat-pathway
#7
REVIEW
Fausto Salaffi, Giovanni Giacobazzi, Marco Di Carlo
Chronic pain is nowadays considered not only the mainstay symptom of rheumatic diseases but also "a disease itself." Pain is a multidimensional phenomenon, and in inflammatory arthritis, it derives from multiple mechanisms, involving both synovitis (release of a great number of cytokines) and peripheral and central pain-processing mechanisms (sensitization). In the last years, the JAK-STAT pathway has been recognized as a pivotal component both in the inflammatory process and in pain amplification in the central nervous system...
2018: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/29622035/ccl17-blockade-as-a-therapy-for-osteoarthritis-pain-and-disease
#8
Ming-Chin Lee, Reem Saleh, Adrian Achuthan, Andrew J Fleetwood, Irmgard Förster, John A Hamilton, Andrew D Cook
BACKGROUND: Granulocyte macrophage-colony stimulating factor (GM-CSF) has been implicated in the pathogenesis of a number of inflammatory diseases and in osteoarthritis (OA). We identified previously a new GM-CSF→Jmjd3→interferon regulatory factor 4 (IRF4)→chemokine (c-c motif) ligand 17 (CCL17) pathway, which is important for the development of inflammatory arthritis pain and disease. Tumour necrosis factor (TNF) can also be linked with this pathway. Here we investigated the involvement of the pathway in OA pain and disease development using the GM-CSF-dependent collagenase-induced OA (CiOA) model...
April 5, 2018: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/29619934/assessing-synovitis-with-conventional-static-and-dynamic-contrast-enhanced-magnetic-resonance-imaging-in-knee-osteoarthritis
#9
Robert Gc Riis
Knee osteoarthritis (KOA) is one of the most common causes of physical disability in the elderly population. With an increasing ageing and obese population, the prevalence of KOA is expected to rise substantially. The needs for a better understanding of the disease and tools that can predict the course of the disease, for example following treatment, are therefore imperative. 

Inflammation has over the last years been recognised as an important factor for both the symptomatology and disease course in KOA...
April 2018: Danish Medical Journal
https://www.readbyqxmd.com/read/29619351/cases-of-early-infectious-flexor-tenosynovitis-treated-non-surgically-with-antibiotics-immobilization-and-elevation
#10
Ashley M DiPasquale, Emily M Krauss, Andrew Simpson, Daniel E Mckee, Donald H Lalonde
Background: Early infectious flexor tenosynovitis has been treated with urgent surgery by most surgeons since Bunnell wrote the first textbook of hand surgery in 1945. Some surgeons have good experience with non-surgical management of early presenting disease in some cases. Methods: This retrospective chart review included 12 inpatients with early infectious flexor synovitis who received conservative treatment with antibiotics, immobilization, and elevation without surgical drainage...
November 2017: Plastic Surgery
https://www.readbyqxmd.com/read/29618891/arthroscopy-of-the-inferior-compartment-of-the-temporomandibular-joint-a-new-perspective
#11
Raúl González-García, Manuel Moreno-Sánchez, Carlos Moreno-García, Leticia Román-Romero, Florencio Monje
Objective: Arthroscopy of the temporomandibular joint (TMJ) has become a well-standardized non-invasive procedure for the treatment of TMJ internal derangement (ID). Since the last 1980s, no clinical application for arthroscopy of the inferior compartment has been established because of the intrinsic difficulty of the technique and the believing of the absence of clinical relevance for treatment of ID. Methods: We report on a particular case in which arthroscopy of the inferior joint compartment together with the examination of the upper joint space was performed in a patient with ID of the TMJ...
June 2018: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/29618136/the-role-of-ultrasound-defined-tenosynovitis-and-synovitis-in-the-prediction-of-rheumatoid-arthritis-development
#12
Ilfita Sahbudin, Luke Pickup, Peter Nightingale, Gina Allen, Zaeem Cader, Ruchir Singh, Paola de Pablo, Christopher D Buckley, Karim Raza, Andrew Filer
Objectives: Tenosynovitis (TS) is common in early arthritis. However, the value of US-defined TS in predicting RA development is unclear. We assessed the predictive utility of US-defined TS alongside US-defined synovitis and clinical and serological variables in a prospective cohort of early arthritis patients. Methods: One hundred and seven patients with clinically apparent synovitis of one or more joint and symptom duration ⩽3 months underwent baseline clinical, laboratory and US assessment of 19 bilateral joint sites and 16 bilateral tendon compartments...
April 3, 2018: Rheumatology
https://www.readbyqxmd.com/read/29615837/synovitis-in-mice-with-inflammatory-arthritis-monitored-with-quantitative-analysis-of-dynamic-contrast-enhanced-nir-fluorescence-imaging-using-irgd-targeted-liposomes-as-fluorescence-probes
#13
Hao Wu, Haohan Wu, Yanni He, Zhen Gan, Zhili Xu, Meijun Zhou, Sai Liu, Hongmei Liu
Background: Rheumatoid arthritis (RA) is a common inflammatory disorder characterized primarily by synovitis and pannus formation in multiple joints, causing joints destruction and irreversible disability in most cases. Early diagnosis and effective therapy monitoring of RA are of importance for achieving the favorable prognosis. Methods: We first prepared the targeted fluorescence probes, and then explored the feasibility of near-infrared (NIR) fluorescence molecular imaging to detect and evaluate the RA via the targeted fluorescence probes by quantitative analysis in this study...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29609209/unmet-needs-and-the-path-forward-in-joint-disease-associated-with-calcium-pyrophosphate-crystal-deposition
#14
REVIEW
Abhishek Abhishek, Tuhina Neogi, Hyon Choi, Michael Doherty, Ann K Rosenthal, Robert Terkeltaub
Calcium pyrophosphate (CPP) crystal deposition (CPPD) is prevalent, and can be associated with synovitis and joint damage. The older-aged population predominantly affected by CPPD is growing rapidly. Since shortfalls exist in many aspects of CPPD, we conducted an anonymous survey of CPPD unmet needs, prioritized by experts from the Gout, Hyperuricemia and Crystal-Associated Disease Network (G-CAN). We provide our perspectives on the survey results, and propose several CPPD basic and clinical translational research pathways...
April 2, 2018: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/29606664/rheumatoid-arthritis-magnetic-resonance-imaging-score-predicts-therapy-response-results-of-the-german-arthromark-cohort
#15
Philipp Sewerin, Lien Le, Stefan Vordenbäumen, Christoph Schleich, Ruben Sengewein, Ralph Brinks, Georg Pongratz, Ellen Bleck, Juliane Lesch, Ulrich Mansmann, Matthias Schneider, Benedikt Ostendorf
OBJECTIVE: Markers for treatment response in rheumatoid arthritis (RA) are lacking. The aim of the study was to assess the performance of the RA magnetic resonance imaging (MRI) scoring system (RAMRIS) in combination with serum biomarkers to predict response to methotrexate (MTX) treatment in therapy-naive patients with early RA by using high-field MRI. METHODS: Twenty-eight patients with RA were prospectively assessed with baseline 3-T MRI of the clinical dominant hand, 3 and 6 months after MTX...
April 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29601835/photoacoustic-imaging-of-synovial-tissue-hypoxia-in-experimental-post-traumatic-osteoarthritis
#16
REVIEW
Zhongyu Liu, Manting Au, Xuan Wang, Pok-Man Boris Chan, Puxiang Lai, Lei Sun, Yongping Zheng, Limin Rong, Chunyi Wen
OBJECTIVES: This pilot study aimed to investigate the feasibility of non-invasively assessing synovial tissue hypoxia in vivo using photoacoustic (PA) imaging in a post-traumatic osteoarthritis model and explore its correlation with OA severity. METHODS: The three-dimensional vasculature structure and oxygenation level of synovial tissues of destabilization of the medial meniscus (DMM)-induced osteoarthritis (OA) mice were longitudinally monitored using PA imaging...
March 27, 2018: Progress in Biophysics and Molecular Biology
https://www.readbyqxmd.com/read/29600215/tuberculous-tenosynovitis-of-the-wrist-and-the-hand-the-3-anatomo-clinical-forms-described-by-kanavel-about-4-cases
#17
Coulibaly Ndeye Fatou, B A Amadou, Gueye Alioune Badara, Dembele Badara, Daffe Mohamedi, Dieme Charles Bertini
Introduction: Tuberculous tenosynovitis localization is rare. This unusual presentation, often misunderstood, results in frequent misdiagnosis. We report 4 cases of patients which represent the 3 anatomo-clinical forms described by Kanavel. The knowledge of its different manifestations will make it possible to recognize and to suspect the tuberculous origin. Case Report: This was a retrospective study from January 2006 to May 2017 which involved all patients received and treated with tuberculous tenosynovitis...
November 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29600208/intra-articular-osteoid-osteoma-of-femoral-neck-region-a-simplified-treatment-strategy-and-review-of-literature
#18
Gaurav Garg, Rajat Malot
Introduction: Proximal femur is the common site for localization of benign bone lesions, and the diagnosis is often delayed and potentially challenging due to their atypical presentations. Early diagnosis is difficult as intra-articular lesions often present with clinical and radiological features of inflammatory synovitis in the joint. Case Report: Two patients of intra-articular osteoid osteoma in proximal femoral presented with atypical features limb lengthening, minimal reactive bone sclerosis, and multifocal nidus...
November 2017: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/29595279/-systemic-sclerosis-in-2017
#19
Tomáš Soukup, Tomáš Veleta
Systemic sclerosis is classed as a diffuse (systemic) disease of connective tissue. It is a heterogeneous disease significantly shortening life expectancy. Its etiology is unknown. Pathogenetic interplay is assumed to involve a triad of pathological autoimmune inflammation, vasculopathy and fibrosis. Clinical manifestations can be classed based on the preponderant pathogenetic process. Vasculopathy is manifested by secondary Raynauds phenomenon with abnormal findings on the nailfold capillaroscopy, skin telangiectasias, gastric antral vascular ectasia, life threatening scleroderma renal crisis, digital ulcerations and prognostically severe pulmonary arterial hypertension...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29594178/arthroscopic-management-of-pigmented-villonodular-synovitis-of-the-hip-in-children-and-adolescents
#20
S Clifton Willimon, Tim Schrader, Crystal A Perkins
Background: Pigmented villonodular synovitis (PVNS) is a benign proliferative synovial disorder most commonly described to affect the knee in adults. Literature describing PVNS in the pediatric population is limited to 2 small case series and a handful of single-patient case reports. Within these studies, only 2 patients with PVNS of the hip are described. Purpose: To describe the presentation, management, and outcomes of a single-center series of pediatric patients with PVNS of the hip treated with arthroscopic synovectomy...
March 2018: Orthopaedic Journal of Sports Medicine
keyword
keyword
44017
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"