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https://www.readbyqxmd.com/read/28094757/which-joints-and-why-do-rheumatologists-scan-in-rheumatoid-arthritis-by-ultrasonography-a-real-life-experience
#1
Sibel Zehra Aydin, Salih Pay, Nevsun Inanc, Sevil Kamali, Omer Karadag, Paul Emery, Maria-Antonietta D'Agostino
OBJECTIVES: Ultrasonography (US) has been demonstrated to improve assessment of synovitis and disease activity in rheumatoid arthritis (RA). However, the utility and feasibility of US in RA in clinical practice in real life is not known. We aimed to investigate: i) the indications for performing US in RA in daily practice; and ii) whether the number of scanned joints varies according to the purpose. METHODS: Consecutive patients who had a US scan either for diagnosis or follow-up for RA from 5 centres were recruited...
January 15, 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28093481/phylogenetic-and-pathogenic-analysis-of-mycoplasma-synoviae-isolated-from-native-chicken-breeds-in-china
#2
Shikai Sun, Xin Lin, Junmei Liu, Zhongqiang Tian, Feng Chen, Yongchang Cao, Jianping Qin, Tingrong Luo
Mycoplasma synoviae (M. synoviae) infection leads to serious economic losses in the world every year. Between 2013 and 2014, the infectious synovitis, caused by M. synoviae infection, occurred in native chickens in China and resulted in the loss of millions of chickens in Chinese poultry farms. However, there has been no data about phylogenetic and pathogenic analysis of Chinese M. synoviae isolates. In this study, a total of 110 M. synoviae strains were isolated from M. synoviae infected chickens. The isolates identified in the present study were classified into a new distinct subgroup based on analysis of the 5'-end vlhA sequences, tentatively termed the K group...
January 16, 2017: Poultry Science
https://www.readbyqxmd.com/read/28089976/disease-characteristics-and-rheumatoid-arthritis-development-in-patients-with-early-undifferentiated-arthritis-a-2-year-followup-study
#3
Gina H Brinkmann, Ellen S Norli, Tore K Kvien, Anne J Haugen, Lars Grøvle, Halvor Nygaard, Olav Bjørneboe, Cathrine Thunem, Maria D Mjaavatten, Elisabeth Lie
OBJECTIVE: To examine the 2-year disease course in patients with undifferentiated arthritis (UA) focusing on fulfillment of the 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) rheumatoid arthritis (RA) classification criteria. METHODS: Data were provided by the Norwegian Very Early Arthritis Clinic study, which included patients presenting with ≥ 1 swollen joint of ≤ 16 weeks' duration. UA was defined as patients not fulfilling the 2010 ACR/EULAR RA criteria and who did not have a clinical diagnosis other than RA at baseline...
January 15, 2017: Journal of Rheumatology
https://www.readbyqxmd.com/read/28086960/the-relationship-between-synovitis-quantified-by-an-ultrasound-7-joint-inflammation-score-and-physical-disability-in-rheumatoid-arthritis-a-cohort-study
#4
Jakub Závada, Petra Hánová, Jana Hurňáková, Lenka Szczuková, Michal Uher, Šárka Forejtová, Martin Klein, Herman Mann, Marta Olejárová, Olga Růžičková, Olga Šléglová, Karel Hejduk, Karel Pavelka
BACKGROUND: Restoring normal physical functioning is a major therapeutic aim in the management of rheumatoid arthritis (RA). It is unknown, whether the extent of synovial inflammation quantified by musculoskeletal ultrasound (US) can predict current or future capacity for physical functioning. To answer this question we investigated the longitudinal relationship between physical function assessed by the health assessment questionnaire (HAQ) and the German 7-joint ultrasound score (US7S) in a prospective cohort of patients with RA...
January 13, 2017: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28072711/the-coexistence-of-sapho-syndrome-and-rheumatoid-arthritis-a-case-report
#5
Wenrui Xu, Chen Li, Weihong Zhang
RATIONAL: SAPHO (Synovitis-Acne-Pustulosis-Hyperstosis-Osteitis) syndrome is a rare disease featured by its dermatological and osteoarthritic disorders, the latter of which mainly affecting the anterior chest wall, spine, and sacroiliac joint. However, rheumatoid arthritis (RA) is a chronic autoimmune disease, mainly affecting the synovial tissue of small joints in hands and feet. Here, we present an extremely rare case diagnosed with both SAPHO syndrome and RA, with an onset interval of 10 years...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28058962/short-term-effect-of-ultrasound-guided-low-molecular-weight-hyaluronic-acid-injection-on-clinical-outcomes-and-imaging-changes-in-patients-with-rheumatoid-arthritis-of-the-ankle-and-foot-joints-a-randomized-controlled-pilot-trial
#6
Chien-Chih Wang, Si-Huei Lee, Hsiao-Yi Lin, Fu-Wei Liu, Hong-Jen Chiou, Rai-Chi Chan, Chen-Liang Chou
To determine whether hyaluronic acid (HA) injection into rheumatoid arthritis ankles and feet can achieve improvement in foot function and reduce synovial hyper-vascularization. Forty-four patients with RA having unilateral or bilateral painful ankle and foot involvement (N = 75) were studied. All the patients were randomized to receive HA (N = 40) or lidocaine (LI) (N = 35) injection at 2-week intervals; Clinical assessments were performed using a visual analog scale (VAS) and foot function index (FFItotal) including subscales of pain (FFIpain) before injection at baseline, 4 weeks (first evaluation) and 12 weeks (secondary evaluation)...
January 6, 2017: Modern Rheumatology
https://www.readbyqxmd.com/read/28057477/localized-and-diffuse-forms-of-tenosynovial-giant-cell-tumor-formerly-giant-cell-tumor-of-the-tendon-sheath-and-pigmented-villonodular-synovitis
#7
REVIEW
F Gouin, T Noailles
Tenosynovial giant cell tumor (TSGCT) is a rare benign tumor arising from joint synovia, bursae and tendon sheaths. Their variable clinical presentation is related to variations in site and progression. Localized forms are most frequent in the hands, and diffuse forms in the knee. MRI is necessary and sometimes sufficient for diagnosis. Treatment strategy is guided by progression, symptomatology, location and diathesis. Optimally complete resection is the principle of first-line treatment. Radiation therapy is effective and targeted therapies are promising; both should especially be considered in case of relapse...
January 2, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28053390/effectiveness-of-arthroscopic-elbow-synovectomy-in-rheumatoid-arthritis-patients-long-term-follow-up-of-clinical-and-functional-outcomes
#8
Vivek Shankar, Pankaj Sharma, Ravi Mittal, Samarth Mittal, Uma Kumar, Shivanand Gamanagatti
OBJECTIVE: To determine the long-term clinical and functional results of arthroscopic elbow synovectomy in rheumatoid arthritis patients with refractory elbow synovitis in terms of improvement in pain, function, and active range of motion (AROM) or arc of motion. METHOD: Fifteen rheumatoid elbows in 13 patients, not responding to DMARD therapy and with radiological changes not more than Larsen grade 3 were taken, who underwent arthroscopic elbow synovectomy. The main outcome measured in forms of Mayo Elbow Performance Scale (MEPS) score, measurement of pain using a Visual Analogue Scale (VAS), radiological angles of elbow, disease activity score (DAS-28), arc of motions (AOM) and complications, which were assessed at follow-up periods of 6 months, 24 months, and 30 months...
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28050748/development-of-diagnostic-techniques-for-early-rheumatoid-arthritis-using-positron-emission-tomography-with-11-c-pk11195-and-11-c-ketoprofen-tracers
#9
Satoshi Nozaki, Naoko Ozaki, Shinobu Suzuki, Miki Goto, Aya Mawatari, Yuka Nakatani, Emi Hayashinaka, Yasuhiro Wada, Hisashi Doi, Yasuyoshi Watanabe
PURPOSE: In vivo detection of pathological insults during the early stages of rheumatoid synovitis is essential to allow early anti-inflammatory treatment for prevention of joint destruction. Whether rheumatoid synovitis pathology and the efficacy of therapies can be visualized by positron emission tomography (PET) tracers specific to the inflammatory process was investigated. PROCEDURES: Using a collagen-induced experimental rat model of rheumatoid arthritis, in vivo imaging using the PET tracers [(11)C]PK11195, which binds to the translocator protein mainly expressed on myeloid cells, and [(11)C]ketoprofen, for cyclooxygenase imaging, was performed...
January 3, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/28045646/initial-experience-of-using-dual-energy-ct-with-an-iodine-overlay-image-for-hand-psoriatic-arthritis-comparison-study-with-contrast-enhanced-mr-imaging
#10
Takeshi Fukuda, Yoshinori Umezawa, Shinjiro Tojo, Takenori Yonenaga, Akihiko Asahina, Hidemi Nakagawa, Kunihiko Fukuda
Purpose To determine the feasibility of dual-energy (DE) computed tomography (CT) with an iodine overlay image (IOI) for evaluation of psoriatic arthritis in the hand. Materials and Methods Approval from the institutional ethics committee and written informed consent from all patients were obtained. This prospective study included 16 patients who had psoriasis with finger joint symptoms from January 2015 to January 2016. Contrast material-enhanced (CE) DE CT and 1.5-T CE magnetic resonance (MR) imaging were performed within 1 month of each other...
December 29, 2016: Radiology
https://www.readbyqxmd.com/read/28040812/aquatic-antagonists-cutaneous-sea-urchin-spine-injury
#11
Clifford Hsieh, Erica R Aronson, Arlene M Ruiz de Luzuriaga
Injuries from sea urchin spines are commonly seen in coastal regions with high levels of participation in water activities. Although these injuries may seem minor, the consequences vary based on the location of the injury. Sea urchin spine injuries may cause arthritis and synovitis from spines in the joints. Nonjoint injuries have been reported, and dermatologic aspects of sea urchin spine injuries rarely have been discussed. We present a case of a patient with sea urchin spines embedded in the thigh who subsequently developed painful skin nodules...
November 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28032093/pigmented-villonodular-synovitis-of-proximal-tibiofibular-joint-rare-site-of-involvement-treated-with-medical-management
#12
Ashish Gulia, Sunita Dhanda, Ajay Puri, Mukta Ramadwar
No abstract text is available yet for this article.
October 2016: South Asian Journal of Cancer
https://www.readbyqxmd.com/read/28028155/abatacept-reduces-disease-activity-and-ultrasound-power-doppler-in-acpa-negative-undifferentiated-arthritis-a-proof-of-concept-clinical-and-imaging-study
#13
Maya H Buch, Elizabeth M A Hensor, Chadi Rakieh, Jane E Freeston, Edward Middleton, Sarah Horton, Sudipto Das, Charles Peterfy, Ai Lyn Tan, Richard J Wakefield, Paul Emery
OBJECTIVES: No proven treatment exists for ACPA-negative undifferentiated arthritis (UA). The aim of this study was to evaluate whether abatacept is effective in treating poor prognosis, ACPA-negative UA, including its effect on power Doppler on US (PDUS). METHODS: A proof-of-concept, open-label, prospective study of 20 patients with DMARD-naïve, ACPA-negative UA (⩾2 joint synovitis) and PDUS ⩾ 1 with clinical and 20-joint US (grey scale/PDUS) assessments at baseline, 6, 12, 18 and 24 months...
January 2017: Rheumatology
https://www.readbyqxmd.com/read/28013325/intra-articular-pathologies-associated-with-chronic-ankle-instability
#14
Henryk Liszka, Paweł Depukat, Artur Gądek
Chronic ankle instability causes intra-articular lesions, which may lead to secondary degenerative changes. The aim of this study was to evaluate the usefulness of the ankle arthroscopy for the evaluation and treatment of intra-articular pathologies associated with chronic ankle instability. Between January 2013 and March 2016, 25 anterior ankle arthroscopies with modi ed anatomic Broström-Duquennoy-Tourne lateral ankle ligaments reconstructions were performed. In arthroscopy all patients (100%) had some intra-articular pathologies: 75% synovitis or so tissue scarring, 19% - deep chondral defect, 56% - superficial chondral lesion, 52% - osteophytes, 24% - bony or avulsion fragments, 20% - loose bodies...
2016: Folia Medica Cracoviensia
https://www.readbyqxmd.com/read/28010726/increase-in-circulating-th17-cells-during-anti-tnf-therapy-is-associated-with-ultrasonographic-improvement-of-synovitis-in-rheumatoid-arthritis
#15
Dobrina N Hull, Helen Cooksley, Shilpa Chokshi, Richard O Williams, Sonya Abraham, Peter C Taylor
BACKGROUND: Anti-TNF agents have revolutionised rheumatoid arthritis (RA) treatment; however, a third of patients fail to achieve therapeutic responses. Unexpectedly, studies in murine and human arthritis have indicated that anti-TNF treatment can increase circulating T helper 17 (Th17) cells, but the relationship to treatment response is unclear. To identify immune correlates of anti-TNF treatment response, we conducted a longitudinal study using clinical, ultrasound and T cell assessments...
December 23, 2016: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/28005642/tumorlike-pigmented-villonodular-synovitis-with-atypical-location-appearance-on-3-phase-99mtc-mdp-bone-scan
#16
Qian Hua, Jianming Ni
Pigmented villonodular synovitis (PVNS) is a proliferative disorder of unknown etiology that originates from the synovial membranes of joints. Some PVNS lesions have been misdiagnosed as malignancy due to their tumorlike imaging findings. There are few reports of PVNS on nuclear 3-phase bone imaging. However, 3-phase Tc-MDP bone scan can offer additional information about the dynamic flow features of the lesion, which may do help in differential benign and malignant. The present report describes 3-phase bone imaging in a surgically proven case of PVNS with tumorlike appearance and atypical location...
December 21, 2016: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28003493/what-drives-osteoarthritis-synovial-versus-subchondral-bone-pathology
#17
REVIEW
Thomas Hügle, Jeroen Geurts
Subchondral bone and the synovium play an important role in the initiation and progression of OA. MRI often permits an early detection of synovial hypertrophy and bone marrow lesions, both of which can precede cartilage damage. Newer imaging modalities including CT osteoabsorptiometry and hybrid SPECT-CT have underlined the importance of bone in OA pathogenesis. The subchondral bone in OA undergoes an uncoupled remodelling process, which is notably characterized by macrophage infiltration and osteoclast formation...
December 21, 2016: Rheumatology
https://www.readbyqxmd.com/read/28000345/orthopedic-and-histopathological-study-on-detritic-synovitis-in-cases-of-primary-and-revision-total-hip-arthroplasty
#18
Takeshi Masuda, Atsushi Takahashi
No abstract text is available yet for this article.
December 20, 2016: Pathology International
https://www.readbyqxmd.com/read/27998641/biocomposite-implants-composed-of-poly-lactide-co-glycolide-%C3%AE-tricalcium-phosphate-systematic-review-of-imaging-complication-and-performance-outcomes
#19
REVIEW
F Alan Barber, David B Spenciner, Samir Bhattacharyya, Larry E Miller
PURPOSE: To determine the degradation and performance outcomes of poly(lactide-co-glycolide)/β-tricalcium phosphate (PLGA/β-TCP) implants. METHODS: A MEDLINE and Embase search for randomized or nonrandomized controlled studies and prospective or retrospective case series that used biocomposite interference screws or suture anchors composed of PLGA/β-TCP was performed. Main outcomes included volume of implant resorption and incidence of osteoconductivity at implant sites, imaging findings, adverse events, and the frequency of reoperations...
December 17, 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/27998036/associations-between-clinical-evidence-of-inflammation-and-synovitis-in-symptomatic-knee-osteoarthritis-a-substudy-of-the-video-trial
#20
Gemma Wallace, Suzie Cro, Caroline Doré, Leonard King, Stefan Kluzek, Andrew Price, Frank Roemer, Ali Guermazi, Richard Keen, Nigel Arden
Objective Painful knee osteoarthritis (KOA) has been associated with joint inflammation. There is however little literature correlating signs of localised inflammation with Contrast-enhanced (CE) Magnetic resonance imaging (MRI) of synovium. This study examined the relationship between clinical and functional markers of localised knee inflammation and CE MRI based synovial scores. Methods Patients with symptomatic KOA were enrolled into the randomised, double-blind, Vitamin D Evaluation in Osteoarthritis (VIDEO) trial...
December 20, 2016: Arthritis Care & Research
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