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https://www.readbyqxmd.com/read/28513977/use-of-high-performance-polymers-as-dental-implant-abutments-and-frameworks-a-case-series-report
#1
Mohammad Al-Rabab'ah, Wala'a Hamadneh, Ismail Alsalem, Ameen Khraisat, Ashraf Abu Karaky
Dental implant abutments can be made of different materials including titanium, gold, zirconia, alumina, and polymeric materials. Polyetheretherketone (PEEK) is a high performance thermoplastic polymer that can be used as a dental implant abutment material. It has an elastic modulus comparable to bone and can reduce stress shielding. PEEK is a radiolucent material that can allow better radiographic imaging of peri-implant tissues and can be veneered with composite materials or bonded to ceramics. PEEK is widely used in orthopedic and spinal surgeries, and it possesses mechanical and biological characteristics that encourage its use as dental implant abutments...
May 17, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28512475/risk-factors-for-road-traffic-injuries-among-different-road-users-in-the-gambia
#2
Edrisa Sanyang, Corinne Peek-Asa, Paul Bass, Tracy L Young, Babanding Daffeh, Laurence J Fuortes
We identified risk factors for road traffic injuries among road users who received treatment at two major trauma hospitals in urban Gambia. The study includes pedestrians, bicyclists, motorcyclists, and drivers/passengers of cars and trucks. We examined distributions of injury by age, gender, collision vehicle types and vehicle category, and driver and environment factors. Two hundred and fifty-four patients were included in the study. Two-thirds were male and one-third female. Two-thirds (67%) of road traffic injuries involved pedestrians, bicyclists, and motorcyclists; and these were more common during weekdays (74%) than weekends...
2017: Journal of Environmental and Public Health
https://www.readbyqxmd.com/read/28511802/-a-continuous-series-of-27-adult-patients-treated-for-l5-s1-isthmic-spondylolisthesis-by-combined-approach-clinical-and-radiological-outcomes-at-1-year-follow-up
#3
N Koné, E Freitas Olim, P Coloma, A Rusconi, L Chenin, O Sy, I S Souaré, C Barrey
Through this single-center consecutive prospective study, we evaluated the results of a combined approach for L5-S1 isthmic spondylolisthesis, using a polyetheretherketone (PEEK) interbody lordotic cage during anterior approach and pedicle screw-based posterior fixation. Between 2010 and 2014, 27 adult patients were treated for L5-S1 isthmic spondylolisthesis (high and low grades) by a combined approach with a minimum follow-up of one year. Clinical outcome was assessed before surgical treatment and at four months and one year after surgery by: VAS, Oswestry Index (ODI) and Rolland-Morris scores...
May 13, 2017: Neuro-Chirurgie
https://www.readbyqxmd.com/read/28502610/functional-connectivity-alterations-in-a-murine-model-of-optic-neuritis
#4
Patrick W Wright, Angela S Archambault, Stacey Peek, Adam Q Bauer, Susan M Culican, Beau M Ances, Joseph P Culver, Gregory F Wu
The basis for neuronal dysfunction following inflammatory demyelination of the central nervous system (CNS) remains poorly understood. We characterized the network response to white matter injury in the anterior visual pathway using an experimental model of optic neuritis (ON), as ON is often an early manifestation of immune-mediated CNS demyelination in multiple sclerosis (MS). Optical intrinsic signal imaging was performed before and after the induction of ON in mice to measure changes in cortical network functional connectivity...
May 11, 2017: Experimental Neurology
https://www.readbyqxmd.com/read/28494799/a-systematic-review-of-electronic-audit-and-feedback-intervention-effectiveness-and-use-of-behaviour-change-theory
#5
REVIEW
Timothy Tuti, Jacinta Nzinga, Martin Njoroge, Benjamin Brown, Niels Peek, Mike English, Chris Paton, Sabine N van der Veer
BACKGROUND: Audit and feedback is a common intervention for supporting clinical behaviour change. Increasingly, health data are available in electronic format. Yet, little is known regarding if and how electronic audit and feedback (e-A&F) improves quality of care in practice. OBJECTIVE: The study aimed to assess the effectiveness of e-A&F interventions in a primary care and hospital context and to identify theoretical mechanisms of behaviour change underlying these interventions...
May 12, 2017: Implementation Science: IS
https://www.readbyqxmd.com/read/28485082/peeking-beneath-the-hood-of-the-leaf-economics-spectrum
#6
Peter B Reich, Habacuc Flores-Moreno
No abstract text is available yet for this article.
June 2017: New Phytologist
https://www.readbyqxmd.com/read/28485068/wear-resistance-of-poly-2-methacryloyloxyethyl-phosphorylcholine-grafted-carbon-fiber-reinforced-poly-ether-ether-ketone-liners-against-metal-and-ceramic-femoral-heads
#7
Shihori Yamane, Masayuki Kyomoto, Toru Moro, Masami Hashimoto, Yoshio Takatori, Sakae Tanaka, Kazuhiko Ishihara
Younger, active patients who undergo total hip arthroplasty (THA) have increasing needs for wider range of motion and improved stability of the joint. Therefore, bearing materials having not only higher wear resistance but also mechanical strength are required. Carbon fiber-reinforced poly(ether ether ketone) (CFR-PEEK) is known as a super engineering plastic that has great mechanical strength. In this study, we focused on poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC)-grafted CFR-PEEK and investigated the effects of PMPC grafting and the femoral heads materials on the wear properties of CFR-PEEK liners...
May 9, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28482601/functionalized-biocompatible-and-impermeable-nanoscale-coatings-for-peek
#8
Firas Awaja, Pieter Cools, Birgit Lohberger, Anton Yu Nikiforov, Giorgio Speranza, Rino Morent
Biologically compatible coatings that provide hermetic seal could resolve a major technological hurdle in the attempt to replace metals with polymers for biochips and active medical implants. The use of amorphous carbon/diamond like carbon (a-C:H) coatings to hermetically seal and biologically enhance polyether-ether-ketone (PEEK) for biomedical device integration in the human body was investigated. The PEEK coating functionality (sp3/sp2 ratio), hardness and thickness (70-200nm) were controlled, by varying H2 and N2 concentration during the plasma operation with CH4...
July 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28481392/customised-cranioplasty-implant-for-decompressive-craniectomy-patients-a-technical-note
#9
Kaif Mohammad
Cranioplasty is a commonly performed procedure following decompressive craniectomy. The patients are usually young earning persons and increasing cost of treatment is difficult to bear especially in low and middle income countries. A variety of options are available for cranioplasty ranging from autologus bone graft to xenograft and synthetic materials. Presently the autologous cryopreserved or subcutaneously preserved bone graft is considered as preferred choice but is has its drawback of bone resorption and infection ...
March 25, 2017: Turkish Neurosurgery
https://www.readbyqxmd.com/read/28480604/initial-experiences-with-a-new-design-for-a-preattached-intravenous-port-device
#10
Ching-Yang Wu, Jui-Ying Fu, Ching-Feng Wu, Chia-Hui Cheng, Yen-Ting Liu, Po-Jen Ko, Yun-Hen Liu, Yen Chu
All available conventional ports share a common design, including catheter, locking nut, and port body, and all share two sites of structural weakness. One site is the junction between the locking nut and the proximal end of the catheter. The other site is the catheter fixation site between the locking nut and the protruding stud of the connecting tube. To overcome these shortcomings, we designed a new type of intravenous port which combines the connecting tube into one piece. The aims of this study were to test the mechanical characteristics of the new design and assess its safety in animal study...
May 8, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28480474/secondary-use-and-analysis-of-big-data-collected-for-patient-care-contribution-from-the-imia-working-group-on-data-mining-and-big-data-analytics
#11
F J Martin-Sanchez, V Aguiar-Pulido, G H Lopez-Campos, N Peek, L Sacchi
OBJECTIVES: To identify common methodological challenges and review relevant initiatives related to the re-use of patient data collected in routine clinical care, as well as to analyze the economic benefits derived from the secondary use of this data. Through the use of several examples, this article aims to provide a glimpse into the different areas of application, namely clinical research, genomic research, study of environmental factors, and population and health services research...
May 8, 2017: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/28474880/enhanced-bioactivity-and-bacteriostasis-of-surface-fluorinated-polyetheretherketone
#12
Meiling Chen, Liping Ouyang, Tao Lu, Heying Wang, Fanhao Meng, Yan Yang, Congqin Ning, Jingzhi Ma, Xuanyong Liu
Although polyetheretherketone (PEEK) has been considered as a potential orthopedic and dental application material due to its similar elastic modulus as bones, inferior osseointegration and bacteriostasis of PEEK hampers its clinical application. In this work, fluorinated PEEK was constructed via plasma immersion ion implantation (PIII) followed by hydrofluoric acid treatment to ameliorate the osseointegration and antibacterial properties of PEEK. The surface microstructure, composition, and hydrophilicity of all samples were investigated...
May 11, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28474182/homogenous-scaffold-based-cranial-skull-implant-modelling-and-structural-analysis-unit-cell-algorithm-meshless-approach
#13
V Phanindra Bogu, Y Ravi Kumar, Asit Kumar Khanra
This computational study explores a unique modelling approach of the cranial implant, homogenous scaffold algorithm and meshless method, respectively. This meshless method is employed to review the implant underneath intracranial pressure (ICP) conditions with a standard ICP range of 7 mm of Hg to 15 mm of Hg. The algorithm is used to introduce uniform porosity within the implant enabling the implant behaviour with respect to ICP conditions. However, increase in the porosity leads to variation in deformation and equivalent stress, respectively...
May 5, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28473630/epidermal-growth-factor-receptor-inhibition-downregulates-helicobacter-pylori-induced-epithelial-inflammatory-responses-dna-damage-and-gastric-carcinogenesis
#14
Johanna C Sierra, Mohammad Asim, Thomas G Verriere, M Blanca Piazuelo, Giovanni Suarez, Judith Romero-Gallo, Alberto G Delgado, Lydia E Wroblewski, Daniel P Barry, Richard M Peek, Alain P Gobert, Keith T Wilson
OBJECTIVE: Gastric cancer is the third leading cause of cancer death worldwide and infection by Helicobacter pylori is the strongest risk factor. We have reported increased epidermal growth factor receptor (EGFR) phosphorylation in the H. pylori-induced human carcinogenesis cascade, and association with DNA damage. Our goal was to determine the role of EGFR activation in gastric carcinogenesis. DESIGN: We evaluated gefitinib, a specific EGFR inhibitor, in chemoprevention of H...
May 4, 2017: Gut
https://www.readbyqxmd.com/read/28465722/does-partial-coating-with-titanium-improve-the-radiographic-fusion-rate-of-empty-peek-cages-in-cervical-spine-surgery-a-comparative-analysis-of-clinical-data
#15
Andreas Kotsias, Sven Mularski, Björn Kühn, Michael Hanna, Olaf Suess
BACKGROUND: Anterior cervical diskectomy and fusion (ACDF) is a well-established surgical treatment. Several types of intervertebral spacers can be used, but there is increasing evidence that PEEK cages yield insufficient fusion and thus less clinical improvement. The study aim was to assess the outcomes of single-level ACDF with an empty PEEK cage partially coated with titanium. METHODS: This prospective multicenter single-arm clinical study collected follow-up data at 6, 12, and 18 months...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28465721/empty-polyetheretherketone-peek-cages-in-anterior-cervical-diskectomy-and-fusion-acdf-show-slow-radiographic-fusion-that-reduces-clinical-improvement-results-from-the-prospective-multicenter-pierce-peek-study
#16
Olaf Suess, Martin Schomaker, Mario Cabraja, Marco Danne, Theodoros Kombos, Michael Hanna
BACKGROUND: Anterior cervical diskectomy and fusion (ACDF) is a well-established surgical treatment for radiculopathy and myelopathy. Previous studies showed that empty PEEK cages have lower radiographic fusion rates, but the clinical relevance remains unclear. This paper's aim is to provide high-quality evidence on the outcomes of ACDF with empty PEEK cages and on the relevance of radiographic fusion for clinical outcomes. METHODS: This large prospective multicenter clinical trial performed single-level ACDF with empty PEEK cages on patients with cervical radiculopathy or myelopathy...
2017: Patient Safety in Surgery
https://www.readbyqxmd.com/read/28464402/trends-and-characteristics-of-occupational-suicide-and-homicide-in-farmers-and-agriculture-workers-1992-2010
#17
Wendy Ringgenberg, Corinne Peek-Asa, Kelley Donham, Marizen Ramirez
OBJECTIVE: We examined work-related homicides and suicides among farm operators/workers in the United States from 1992 to 2010. METHODS: Work-related homicide and suicide cases from 1992 to 2010 were obtained from the Census of Fatal Occupational Injuries. To calculate rates, denominator data on the US working population were also obtained from 2003 to 2010 Current Population Survey. Logistic regression was used to identify factors that were differentially associated with homicide and suicide...
May 2, 2017: Journal of Rural Health
https://www.readbyqxmd.com/read/28463496/interfacial-phenomena-and-mechanical-behavior-of-polyetheretherketone-polybenzimidazole-blend-under-hygrothermal-environment
#18
Peng Liu, Michael Mullins, Tim Bremner, Natalie Benner, Hung-Jue Sue
Demands for engineering applications of high performance polymers, such as the polyaryletherketone families, have grown significantly in recent years. Fundamental knowledge on mechanical behavior of such polymers, especially under harsh environments, is still lacking. In this study, the mechanical behavior and interfacial phenomena of a blend of polybenzimidazole (PBI) particles having sizes of about 50 µm and polyetheretherketone (PEEK) matrix at 50:50 weight ratio was characterized. PBI and PEEK are known to be incompatible with each other in the dry state...
May 2, 2017: Journal of Physical Chemistry. B
https://www.readbyqxmd.com/read/28446192/prospective-clinical-and-radiographic-evaluation-of-an-allogeneic-bone-matrix-containing-stem-cells-trinity-evolution%C3%A2-viable-cellular-bone-matrix-in-patients-undergoing-two-level-anterior-cervical-discectomy-and-fusion
#19
Timothy A Peppers, Dennis E Bullard, Jed S Vanichkachorn, Scott K Stanley, Paul M Arnold, Erik I Waldorff, Rebekah Hahn, Brent L Atkinson, James T Ryaby, Raymond J Linovitz
BACKGROUND: Trinity Evolution® (TE), a viable cellular bone allograft, previously demonstrated high fusion rates and no safety-related concerns after single-level anterior cervical discectomy and fusion (ACDF) procedures. This prospective multicenter clinical study was performed to assess the radiographic and clinical outcomes of TE in subjects undergoing two-level ACDF procedures. METHODS: In a prospective, multicenter study, 40 subjects that presented with symptomatic cervical degeneration at two adjacent vertebral levels underwent instrumented ACDF using TE autograft substitute in a polyetherethereketone (PEEK) cage...
April 26, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28442434/clinical-code-set-engineering-for-reusing-ehr-data-for-research-a-review
#20
REVIEW
Richard Williams, Evangelos Kontopantelis, Iain Buchan, Niels Peek
INTRODUCTION: The construction of reliable, reusable clinical code sets is essential when re-using Electronic Health Record (EHR) data for research. Yet code set definitions are rarely transparent and their sharing is almost non-existent. There is a lack of methodological standards for the management (construction, sharing, revision and reuse) of clinical code sets which needs to be addressed to ensure the reliability and credibility of studies which use code sets. OBJECTIVE: To review methodological literature on the management of sets of clinical codes used in research on clinical databases and to provide a list of best practice recommendations for future studies and software tools...
April 22, 2017: Journal of Biomedical Informatics
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