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https://www.readbyqxmd.com/read/27908615/unilaterally-posterior-lumbar-interbody-fusion-with-double-expandable-peek-cages-without-pedicle-screw-support-for-lumbar-disc-herniation
#1
Aydemir Kale, Ibrahim Ilker Oz, Ayhan Onk, Murat Kalaycı, Çağatay Büyükuysal
OBJECTIVES: Posterior lumbar interbody fusion (PLIF) is usually bilateral procedure, and it is combined with posterior by bilateral pedicle screw support or with fixation. The purpose of this retrospective study was to compare the surgical outcomes of simple discectomy and PLIF without pedicle screw support in patients with lumbar disc herniation (LDH). PATIENTS AND METHODS: 60 patients with single segment LDH were operated between February 2010 and June 2013. 40 patients were treated with simple discectomy (Group 1) and 20 patients were treated with PLIF using double expandable polyetheretherketone (PEEK) cages without instrumentation (Group 2) unilaterally...
November 17, 2016: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/27885473/the-application-of-a-new-type-of-titanium-mesh-cage-in-hybrid-anterior-decompression-and-fusion-technique-for-the-treatment-of-continuously-three-level-cervical-spondylotic-myelopathy
#2
Xiaowei Liu, Yu Chen, Haisong Yang, Tiefeng Li, Haidong Xu, Bin Xu, Deyu Chen
PURPOSE: To evaluate the efficacy and safety of a new type of titanium mesh cage (NTMC) in hybrid anterior decompression and fusion method (HDF) in treating continuously three-level cervical spondylotic myelopathy (TCSM). METHODS: Ninety-four cases who had TCSM and accepted the HDF from Jan 2007 to Jan 2010 were included. Clinical and radiological outcomes were compared between cases who had the NTMC (Group A, n = 45) and traditional titanium mesh cage (TTMC, Group B, n = 49) after corpectomies...
November 24, 2016: European Spine Journal
https://www.readbyqxmd.com/read/27885355/applying-the-mini-open-anterolateral-lumbar-interbody-fusion-with-self-anchored-stand-alone-polyetheretherketone-cage-in-lumbar-revision-surgery
#3
Lei Kuang, Yuqiao Chen, Lei Li, Guohua Lü, Bing Wang
The author retrospectively studied twenty-two patients who underwent revision lumbar surgeries using ALLIF with a self-anchored stand-alone polyetheretherketone (PEEK) cage. The operation time, blood loss, and perioperative complications were evaluated. Oswestry disability index (ODI) scores and visual analog scale (VAS) scores of leg and back pain were analyzed preoperatively and at each time point of postoperative follow-up. Radiological evaluation including fusion, disc height, foraminal height, and subsidence was assessed...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27881916/osseointegration-of-nanohydroxyapatite-or-nano-calcium-silicate-incorporated-polyetheretherketone-bioactive-composites-in-vivo
#4
Rui Ma, Zhifeng Yu, Songchao Tang, Yongkang Pan, Jie Wei, Tingting Tang
Polyetheretherketone (PEEK) exhibits appropriate biomechanical strength as well as good biocompatibility and stable chemical properties but lacks bioactivity and cannot achieve highly efficient osseointegration after implantation. Incorporating bioceramics into the PEEK matrix is a feasible approach for improving its bioactivity. In this study, nanohydroxyapatite (n-HA) and nano-calcium silicate (n-CS) were separately incorporated into PEEK to prepare n-HA/PEEK and n-CS/PEEK biocomposites, respectively, using a compounding and injection-molding technique, and the in vitro degradation characteristics were evaluated...
2016: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/27873412/what-s-in-a-name-word-inflation-punctuation-abbreviation-and-cloud-formation
#5
Susie J Schofield, Pieta G Schofield
The title of a journal paper offers a crucial portal into any scientific field. It determines whether interested readers locate the paper and whether others have enough interest sparked to lead them to read the abstract. This article looks at authored journal paper titles in Medical Education over its first 50 years (n = 6357) of publication and Medical Teacher over its first 35 years of publication, revealing both trends in areas of interest and how those interests are worded. Word clouds per decade showed a shift from teaching to learning and from examination to assessment, and new foci on learning, patients, research and feedback in both journals...
December 2016: Medical Education
https://www.readbyqxmd.com/read/27870490/peeking-into-the-molecular-trove-of-discarded-surgical-specimens
#6
EDITORIAL
Alex W Hewitt, Anthony L Cook, Alice Pébay
No abstract text is available yet for this article.
November 2016: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/27865449/characterizing-nuclear-and-mitochondrial-dna-in-spent-embryo%C3%A2-culture-media-genetic-contamination-identified
#7
Elizabeth R Hammond, Brent C McGillivray, Sophie M Wicker, John C Peek, Andrew N Shelling, Peter Stone, Larry W Chamley, Lynsey M Cree
OBJECTIVE: To characterize nuclear and mitochondrial DNA (mtDNA) in spent culture media from normally developing blastocysts to determine whether it could be used for noninvasive genetic assessment. DESIGN: Prospective embryo cohort study. SETTING: Academic center and private in vitro fertilization (IVF) clinic. PATIENT(S): Seventy patients undergoing intracytoplasmic sperm injection (ICSI) and 227 blastocysts. INTERVENTION(S): Culture media assessment, artificial blastocoele fluid collapse and DNA analysis using digital polymerase chain reaction (dPCR), long-range PCR, quantitative PCR (qPCR), and DNA fingerprinting...
November 16, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27852028/-the-meaning-of-understanding-the-brain-peeking-into-the-brain-of-a-computational-neuroscientist
#8
Hirokazu Tanaka
What does "understanding the brain" mean? Here, I review how computational neuroscience, a theoretical approach to the brain, can aid our understanding of the brain. First, I illustrate the study of reinforcement learning and dopamine neurons and argue its success in the light of Marr's three levels of computation. Second, I discuss how Marr's program has led to a computational understanding of the brain, and present computational models of the motor cortex and of a spiking neural network as illustrative examples...
November 2016: Brain and Nerve, Shinkei Kenkyū No Shinpo
https://www.readbyqxmd.com/read/27821537/-there-was-no-great-ceremony-patient-narratives-and-the-diagnostic-encounter-in-the-context-of-parkinson-s
#9
Jane Peek
This paper draws on stories of diagnosis that emerged from a broader narrative study exploring the lived experience of Parkinson's (n.37). Despite the life-changing nature of their diagnosis, participants' narratives highlighted considerable shortcomings in the way in which their diagnostic encounter was handled, echoing the findings of previous research in which it has been noted that 'the human significance' of diagnosis was passed over. Building on the literature, this paper provides empirical material that reveals the sensitivities involved at the moment of diagnosis...
November 7, 2016: Medical Humanities
https://www.readbyqxmd.com/read/27813453/prevalence-and-risk-factors-associated-with-work-related-eye-injuries-in-bosnia-and-herzegovina
#10
Nina Jovanovic, Corinne Peek-Asa, Amanda Swanton, Tracy Young, Jasmina Alajbegovic-Halimic, Semra Cavaljuga, Faruk Nisic
BACKGROUND: Eye injuries are a prevalent workplace injury and cause substantial disability when vision is impaired. OBJECTIVE: To examine work-relatedness of demographic, injury, and clinical characteristics of eye injuries in a large clinic in Bosnia and Herzegovina. METHODS: We performed a nine-year retrospective study of patients admitted with an eye injury to the Canton Hospital in Zenica, Bosnia and Herzeogvina. Controlling for age and sex, we used logistic regression to examine the influence of work-relatedness on patient and injury characteristics and clinical outcomes...
October 2016: International Journal of Occupational and Environmental Health
https://www.readbyqxmd.com/read/27807807/volunteering-in-adolescence-and-young-adulthood-crime-involvement-a-longitudinal-analysis-from-the-add-health-study
#11
Shabbar I Ranapurwala, Carri Casteel, Corinne Peek-Asa
BACKGROUND: Experiences in adolescence may have a lasting impact on adulthood. The objective of this study is to evaluate the association between adolescent (12-18 years of age) volunteerism with the incidence of illegal behaviors, arrests, and convictions in adulthood (>18 years of age). METHODS: We conducted a retrospective cohort study using secondary data from the National Longitudinal Study of Adolescent to Adult Health. Students from grades 7-12 were recruited in 1994-1995 (n = 20,745), and then followed in 2001-2002 (n = 14,322) and in 2008-2009 (n = 12,288)...
December 2016: Injury Epidemiology
https://www.readbyqxmd.com/read/27799989/surgical-outcomes-of-anterior-cervical-fusion-using-deminaralized-bone-matrix-as-stand-alone-graft-material-single-arm-pilot-study
#12
Ho-Jung Chung, Jung-Woo Hur, Kyeong-Sik Ryu, Jin-Sung Kim, Ji-Hoon Seong
OBJECTIVE: To investigate the safety and efficacy of demineralized bone matrix (DBM) as a bone graft substitute for anterior cervical discectomy and fusion (ACDF) surgery. METHODS: Twenty consecutive patients treated with ACDF using stand-alone polyestheretherketone (PEEK) cages (Zero-P) with DBM(CGDBM100) were prospectively evaluated with a minimum of 6 months of follow-up. Radiologic efficacy was evaluated with a 6-point scoring method for osseous fusion using plain radiograph and computed tomogrpahy scans...
September 2016: Korean Journal of Spine
https://www.readbyqxmd.com/read/27799985/comparison-of-radiologic-outcomes-of-different-methods-in-single-level-anterior-cervical-discectomy-and-fusion
#13
O Ik Kwon, Dong Wuk Son, Sang Weon Lee, Geun Sung Song
OBJECTIVE: Anterior cervical discectomy and fusion (ACDF) is a choice of surgical procedure for cervical degenerative diseases associated with radiculopathy or myelopathy. However, the patients undergoing ACDF still have problems. The purpose of the present study is to evaluate the radiologic results of 3 different methods in single-level ACDF. METHODS: We conducted a retrospective collection of radiological data from January 2011 to December 2014. A total of 67 patients were included in this study...
September 2016: Korean Journal of Spine
https://www.readbyqxmd.com/read/27787358/predicting-mortality-from-change-over-time-in-the-charlson-comorbidity-index-a-retrospective-cohort-study-in-a-data-intensive-uk-health-system
#14
Paolo Fraccaro, Evangelos Kontopantelis, Matthew Sperrin, Niels Peek, Christian Mallen, Philip Urban, Iain E Buchan, Mamas A Mamas
Multimorbidity is common among older people and presents a major challenge to health systems worldwide. Metrics of multimorbidity are, however, crude: focusing on measuring comorbid conditions at single time-points rather than reflecting the longitudinal and additive nature of chronic conditions. In this paper, we explore longitudinal comorbidity metrics and their value in predicting mortality.Using linked primary and secondary care data, we conducted a retrospective cohort study on adults in Salford, UK from 2005 to 2014 (n = 287,459)...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27783845/cementogenesis-and-osteogenesis-in-periodontal-tissue-regeneration-by-recombinant-human-transforming-growth-factor-%C3%AE-3-a-pilot-study-in-papio-ursinus
#15
Ugo Ripamonti, Ruqayya Parak, Roland M Klar, Caroline Dickens, Therese Dix-Peek, Raquel Duarte
OBJECTIVES: The aim of this study was to investigate cementogenesis and alveolar bone induction during in vivo periodontal tissue regeneration upon implantation of hTGF-β3 in furcation defects of Papio ursinus and to evaluate the feasibility of gene expression studies. MATERIALS AND METHODS: Class II furcation defects (day 0) were prepared in mandibular first and second molars of three P. ursinus and on day 30 implanted with and without 75 μg hTGF-β3 in Matrigel(®) matrix...
October 26, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27783403/fear-of-falling-in-older-mexican-americans-a-longitudinal-study-of-incidence-and-predictive-factors
#16
Leah Dierking, Kyriakos Markides, Soham Al Snih, M Kristen Peek
OBJECTIVES: To determine predictors of fear of falling in older Mexican Americans over time. DESIGN: Longitudinal study. SETTING: Community-dwelling residents throughout California, Colorado, New Mexico, Arizona, and Texas. PARTICIPANTS: Community-dwelling Mexican Americans aged 72 and older participating in the Hispanic Established Populations for the Epidemiologic Study of the Elderly from 2000-01 to 2010-11 (N = 1,682)...
October 26, 2016: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/27783108/-peek-cage-fusion-after-anterior-cervical-corpectomy-clinical-and-radiological-results-in-patients-with-spondylotic-myelopathy
#17
C Schulz, U M Mauer, R Mathieu
BACKGROUND: Anterior cervical corpectomy and fusion (ACCF) has become a standard procedure for patients with spondylotic myelopathy due to multisegmental stenosis of the cervical canal. In addition to the fusion technique using autogenous bone grafts and titanium implants, synthetic polyetheretherketone (PEEK) cages have been used increasingly during the last years. However, limited evidence on the clinical and radiological results of PEEK cages for ACCF exists in the literature. The study presented here is the largest series to date reporting clinical and radiological outcome as well as complication rates after one to three-level ACCF using PEEK cages augmented by an anterior plate-screw osteosynthesis...
October 25, 2016: Der Orthopäde
https://www.readbyqxmd.com/read/27778233/schools-and-disasters-safety-and-mental-health-assessment-and-interventions-for-children
#18
Betty S Lai, Ann-Margaret Esnard, Sarah R Lowe, Lori Peek
This article draws on experiences and lessons from global disasters and utilizes the United Nations Comprehensive School Safety Framework to highlight the necessary role of safe schools in protecting children, as well as adult staff, from the immediate threats and long-term implications of disasters. Specifically, we focus on three well-established pillars of school safety: Pillar I: Safe Learning Facilities; Pillar II: Disaster Management; and Pillar III: Risk Reduction and Resilience Education. In addition, we propose a potential fourth pillar, which underscores the function of schools in postdisaster mental health assessment and intervention for children...
December 2016: Current Psychiatry Reports
https://www.readbyqxmd.com/read/27774612/the-contributions-of-mental-state-understanding-and-executive-functioning-to-preschool-aged-children-s-lie-telling
#19
Karissa Leduc, Shanna Williams, Carlos Gomez-Garibello, Victoria Talwar
In this study, preschool-aged children's lie-telling behaviour was examined in relation to mental state understanding and executive functioning. Sixty-seven children aged between 25 and 43 months (Mage in months  = 34.80, SD = 4.39) participated in a temptation resistance paradigm (TRP). Children completed emerging ToM tasks measuring the following mental states: (1) diverse beliefs, (2) diverse desires, and (3) knowledge access. Children also completed measures of inhibitory control and working memory...
October 23, 2016: British Journal of Developmental Psychology
https://www.readbyqxmd.com/read/27773696/circadian-clock-interaction-with-hif1%C3%AE-mediates-oxygenic-metabolism-and-anaerobic-glycolysis-in-skeletal-muscle
#20
Clara Bien Peek, Daniel C Levine, Jonathan Cedernaes, Akihiko Taguchi, Yumiko Kobayashi, Stacy J Tsai, Nicolle A Bonar, Maureen R McNulty, Kathryn Moynihan Ramsey, Joseph Bass
Circadian clocks are encoded by a transcription-translation feedback loop that aligns energetic processes with the solar cycle. We show that genetic disruption of the clock activator BMAL1 in skeletal myotubes and fibroblasts increased levels of the hypoxia-inducible factor 1α (HIF1α) under hypoxic conditions. Bmal1(-/-) myotubes displayed reduced anaerobic glycolysis, mitochondrial respiration with glycolytic fuel, and transcription of HIF1α targets Phd3, Vegfa, Mct4, Pk-m, and Ldha, whereas abrogation of the clock repressors CRY1/2 stabilized HIF1α in response to hypoxia...
October 19, 2016: Cell Metabolism
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