keyword
MENU ▼
Read by QxMD icon Read
search

japanese encephalitis

keyword
https://www.readbyqxmd.com/read/29155034/identification-of-a-novel-porcine-oasl-variant-exhibiting-antiviral-activity
#1
Changjing Zhao, Sheng Zheng, Dan Zhu, Xue Lian, Weiting Liu, Feng Hu, Puyan Chen, Ruibing Cao
2', 5'-Oligoadenylate synthetase-lilke (OASL) protein is an atypical oligoadenylate synthetase (OAS) family member, which possesses antiviral activity but lacks 2', 5'-oligoadenylate synthetase activity. Here, a novel variant of porcine OASL (pOASL2) was identified through RT-PCR amplification. This gene is distinguishable from the previously described wild-type porcine OASL (pOASL1). The gene appears to be derived from a truncation of exon 4 plus 8 nucleotides of exon 5 with a premature termination, measuring only 633 bp in length, although its position corresponds to that of pOASL1...
November 15, 2017: Virus Research
https://www.readbyqxmd.com/read/29152704/west-nile-disease-in-tunisia-an-overview-of-60-years
#2
Salah Hammami, Thameur Ben Hassine, Annamaria Conte, Jihène Amdouni, Fabrizio De Massis, Soufiène Sghaier, Sonia Ben Hassen
West Nile virus (WNV) is an arthropod borne virus of public health importance. The virus is a member of the genus Flavivirus and belongs to the Japanese encephalitis virus (JEV) antigenic complex under the Flaviviridae family. The WNV is continuously spreading across Tunisia especially in the coastal and Southern area of the country. The first human West Nile disease (WND) epidemic in Tunisia occurred in 1997, since then, the quantity and the extension of spillover effects increased constantly. However, the existing knowledge of factors triggering such events continues to be rather poor...
September 30, 2017: Veterinaria Italiana
https://www.readbyqxmd.com/read/29149532/exploitation-of-micrornas-by-japanese-encephalitis-virus-in-human-microglial-cells
#3
Meghana Rastogi, Neha Srivastava, Sunit K Singh
JEV infection in CNS leads to the JE neuroinflammation. Children and old age individual have been reported to be more prone to JEV infection. MicroRNAs are endogenous, small non-coding RNAs, which regulate the gene expression. These are ∼22 nucleotide long, conserved RNA sequence that binds at the 3'UTR of a target mRNA and regulate the post-transcriptional gene expression. The role of microRNAs has been reported in several diseases like cancer, viral infection, neuro-degeneration, diabetes etc. In the present study, the human microglial cells were infected with JEV (JaOAr strain)...
November 17, 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/29147873/comparison-of-the-adjuvanticity-of-two-adjuvant-formulations-containing-de-o-acylated-lipooligosaccharide-on-japanese-encephalitis-vaccine-in-mice
#4
Ara Ko, Seo Ri Wui, Ji In Ryu, Hien Thi Thu Do, Yeon Jeong Lee, Soo Jeong Lim, Inmoo Rhee, Dae Im Jung, Jin-Ah Park, Jung-Ah Choi, Man Ki Song, Na Gyong Lee
Adjuvants are essential vaccine components used to enhance, accelerate, and/or prolong adaptive immunity against specific vaccine antigens. In this study, we compared the adjuvanticity of two adjuvant formulations containing de-O-acylated lipooligosaccharide (dLOS), a toll-like receptor 4 agonist, on the Japanese encephalitis (JE) vaccine in mice. Mice were immunized once or twice at a two-week interval with inactivated JE vaccine in the absence or presence of adjuvant. We found that both the alum- and the liposome-based formulation induced significantly faster and higher serum IgG antibody responses as compared with the non-adjuvanted vaccine after either one or two immunizations...
November 17, 2017: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/29119088/neurological-manifestations-of-dengue-infection
#5
REVIEW
Guo-Hong Li, Zhi-Jie Ning, Yi-Ming Liu, Xiao-Hong Li
Dengue counts among the most commonly encountered arboviral diseases, representing the fastest spreading tropical illness in the world. It is prevalent in 128 countries, and each year >2.5 billion people are at risk of dengue virus infection worldwide. Neurological signs of dengue infection are increasingly reported. In this review, the main neurological complications of dengue virus infection, such as central nervous system (CNS), peripheral nervous system, and ophthalmic complications were discussed according to clinical features, treatment and possible pathogenesis...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/29109371/seasonal-patterns-of-japanese-encephalitis-and-associated-meteorological-factors-in-taiwan
#6
Che-Liang Lin, Hsiao-Ling Chang, Chuan-Yao Lin, Kow-Tong Chen
The persistent transmission of Japanese encephalitis virus (JEV) in Taiwan necessitates exploring the risk factors of occurrence of Japanese encephalitis (JE). The purpose of this study was to assess the relationship between meteorological factors and the incidence of JE in Taiwan. We collected data for cases of JE reported to the Taiwan Centers for Disease Control (Taiwan CDC) from 2000 to 2014. Meteorological data were obtained from the Taiwan Central Weather Bureau. The relationships between weather variability and the incidence of JE in Taiwan were determined via Poisson regression analysis and a case-crossover methodology...
October 29, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29108001/retraction-anti-japanese-encephalitis-virus-igm-positivity-among-patients-with-acute-encephalitic-syndrome-admitted-to-different-hospitals-from-all-over-nepal
#7
https://www.readbyqxmd.com/read/29097647/longitudinally-extensive-transverse-myelitis-letm-in-a-case-of-japanese-encephalitis-with-an-unexpected-complication
#8
Srikant Mohta, Animesh Ray, S K Sharma, Surabhi Vyas
No abstract text is available yet for this article.
July 2017: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/29097643/seasonal-occurrence-of-japanese-encephalitis-vectors-in-bareilly-district-uttar-pradesh-india
#9
P B Pantawane, H Dhanze, M R Verma, G Singh, A Kapdi, J Chauhan, K N Bhilegaonkar
BACKGROUND & OBJECTIVES: Japanese encephalitis (JE) is one of the most common causes of acute encephalitis syndrome in many states of India. Uttar Pradesh state is well known for JE endemicity, contributing 75% of total cases during recent past. Several sporadic cases have been reported from Bareilly region of the state. The disease spread by bite of Culex mosquito. Survey of literature revealed no data on mosquito fauna with reference to JE in this region. Therefore, this study was planned to survey seasonal mosquito population and occurrence of JE vectors in Bareilly region...
July 2017: Journal of Vector Borne Diseases
https://www.readbyqxmd.com/read/29093640/identification-of-novel-antiviral-of-fungus-derived-brefeldin-a-against-dengue-viruses
#10
Muhareva Raekiansyah, Mihoko Mori, Kenichi Nonaka, Masanobu Agoh, Kazuro Shiomi, Atsuko Matsumoto, Kouichi Morita
Microbial natural products possess a wide range of biological and biochemical potential. Among them, fungal secondary metabolites are one of the most important sources for discovering new drugs or lead compounds. In the present study, we explored substances produced by the strain Penicillium sp. FKI-7127 for its antiviral activity. We identified brefeldin A as a novel antiviral agent against dengue viruses. The inhibitory effect of brefeldin A was confirmed by virus titer and immunofluorescence assay. Brefeldin A inhibited dengue viruses regardless of serotypes and other related viruses including Zika virus and Japanese encephalitis virus...
2017: Tropical Medicine and Health
https://www.readbyqxmd.com/read/29093094/characterization-of-recombinant-flaviviridae-viruses-possessing-a-small-reporter-tag
#11
Tomokazu Tamura, Takasuke Fukuhara, Takuro Uchida, Chikako Ono, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Takeshi Kurosu, Yin Xiang Setoh, Michio Imamura, Norbert Tautz, Yoshihiro Sakoda, Alexander A Khromykh, Kazuaki Chayama, Yoshiharu Matsuura
The family Flaviviridae consists of four genera, Flavivirus, Pestivirus, Pegivirus, and Hepacivirus, and comprises important pathogens of human and animals. Although the construction of recombinant viruses carrying reporter genes including fluorescent and bioluminescent proteins has been reported, the stable insertion of foreign genes into viral genomes retaining infectivity remains difficult. Here, we applied the 11-amino-acid subunit derived from NanoLuc luciferase to the engineering of the Flaviviridae viruses, and then examined the biological characteristics of the viruses...
November 1, 2017: Journal of Virology
https://www.readbyqxmd.com/read/29083983/investigation-on-mosquito-borne-viruses-at-lancang-river-and-nu-river-watersheds-in-southwestern-china
#12
Lingli Li, Xiaofang Guo, Qiumin Zhao, Yigang Tong, Hang Fan, Qiang Sun, Shaozhen Xing, Hongning Zhou, Jiusong Zhang
During 2007 and 2010, an extensive entomological survey was performed to assess the distribution of mosquitoes and mosquito-borne arboviruses at Lancang River and Nu River watersheds in southwestern China. A total of 20,450 mosquitoes consisting 20 species was trapped and submitted 261 pools according to species and location. Culex tritaeniorhynchus and Anopheles sinensis were the most abundant species. Eighty-seven isolates representing 11 virus species in 8 genera were obtained from 6 mosquito species. The new isolates were identified as Getah virus (GETV), Japanese encephalitis virus (JEV), Yunnan Culex-related flavivirus (YNCxFV), Yunnan Aedes-related flavivirus (YNAeFV), Banna virus (BAV), Yunnan orbivirus (YUOV), Banna orbivirus (BAOV), Yunnan totivirus (YNToV), Nam Dinh virus (NDiV), Menghai rhabdovirus (MRV), and Anopheles minimus iridovirus (AMIV)...
October 30, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/29081368/immunogenicity-and-safety-of-a-single-dose-of-a-live-attenuated-japanese-encephalitis-chimeric-virus-vaccine-in-vietnam-a-single-arm-single-center-study
#13
Vu Dinh Thiem, Nguyen Dang Quang, Tran Thi Ai Huong, Valérie Bosch-Castells, Céline Zocchetti, Guy Houillon
OBJECTIVE: To describe the immunogenicity and safety of the Japanese encephalitis chimeric virus vaccine (JE-CV) in children and adults in Vietnam. METHODS: In this prospective, open-label, single-center, single-arm study, 250 healthy participants aged 9 months to 60 years received a single dose of JE-CV (IMOJEV(®)). JE neutralizing antibody titers were assessed at baseline and 28days after vaccination using the 50% plaque reduction neutralization test (PRNT50)...
October 25, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29076102/epidemiological-profile-of-acute-viral-encephalitis
#14
Rajesh Kumar, Pankaj Kumar, Manoj Kumar Singh, Dipti Agarwal, Bendangienla Jamir, Shashi Khare, Samrendra Narayan
OBJECTIVE: To study the etiology and clinico-epidemiological profile of acute viral encephalitis in children with acute encephalitis syndrome (AES). METHODS: An observational study including 100 patients fulfilling the criteria for AES was conducted in children of age group 1 mo - 16 y. Viral isolation was done on RD cells, HEp-2 cells and Vero cells from the cerebrospinal fluid samples of suspected viral encephalitis (VE) cases. An enzyme immunoassay for IgM antibodies was performed for measles, mumps, Varicella zoster virus (VZV), Herpes simplex virus 1 (HSV1) and Japanese encephalitis virus (JEV)...
October 27, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29075656/rearing-of-culex-spp-and-aedes-spp-mosquitoes
#15
Elizabeth Kauffman, Anne Payne, Mary A Franke, Michael A Schmid, Eva Harris, Laura D Kramer
Mosquito-transmitted pathogens cause major public health problems and contribute substantially to the global burden of disease. Aedes mosquitoes transmit dengue, Zika, yellow fever, and Chikungunya viruses; Culex mosquitoes transmit West Nile, Japanese encephalitis, and Saint Louis encephalitis viruses, among others. Experiments utilizing laboratory-reared colonized mosquitoes can address many issues such as vector biology, vector competence, vector-pathogen interaction, and vector control. The establishment of healthy and standardized mosquito colonies requires generation and implementation of protocols, attention to detail, and an understanding of the factors that affect mosquito fitness, such as temperature and humidity, nutrient quality and availability, population density, blood feeding and mating behavior, and egg-laying requirements...
September 5, 2017: Bio-protocol
https://www.readbyqxmd.com/read/29070887/new-reverse-genetics-and-transfection-methods-to-rescue-arboviruses-in-mosquito-cells
#16
Thérèse Atieh, Antoine Nougairède, Raphaëlle Klitting, Fabien Aubry, Anna-Bella Failloux, Xavier de Lamballerie, Stéphane Priet
Reverse genetics is a critical tool to decrypt the biological properties of arboviruses. However, whilst reverse genetics methods have been usually applied to vertebrate cells, their use in insect cells remains uncommon due to the conjunction of laborious molecular biology techniques and of specific difficulties surrounding the transfection of such cells. To leverage reverse genetics studies in both vertebrate and mosquito cells, we designed an improved DNA transfection protocol for insect cells and then demonstrated that the simple and flexible ISA (Infectious Subgenomic Amplicons) reverse-genetics method can be efficiently applied to both mammalian and mosquito cells to generate in days recombinant infectious positive-stranded RNA viruses belonging to genera Flavivirus (Japanese encephalitis, Yellow fever, West Nile and Zika viruses) and Alphavirus (Chikungunya virus)...
October 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29058581/opsoclonus-myoclonus-syndrome-in-a-patient-with-japanese-encephalitis-a-case-report
#17
Subatharshini Sountharalingam, H M M T B Herath, Dharshana Wijegunasinghe, Sunethra Senanayke
BACKGROUND: Opsoclonus myoclonus syndrome is a rare neurological disorder that usually manifests as a paraneoplastic phenomenon. Although some viruses are reported to cause this condition, opsoclonus myoclonus syndrome by Japanese encephalitis has not been reported previously. CASE PRESENTATION: Here we present the case of a 31-year-old Sri Lankan woman who presented with fever, altered level of consciousness, opsoclonus, and facial myoclonus. She was diagnosed as having Japanese encephalitis based on cerebrospinal fluid and serum Japanese encephalitis-specific immunoglobulin M antibody and characteristic magnetic resonance imaging abnormalities...
October 23, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29058107/zika-virus-isolated-from-mosquitoes-a-field-and-laboratory-investigation-in-china-2016
#18
Shihong Fu, Song Song, Hong Liu, Yuanyuan Li, Xiaolong Li, Xiaoyan Gao, Ziqian Xu, Guoping Liu, Dingming Wang, Zhenzao Tian, Jingzhu Zhou, Ying He, Wenwen Lei, Huanyu Wang, Bin Wang, Xiaoqing Lu, Guodong Liang
A field investigation of arboviruses was conducted in Dejiang, Guizhou Province in the summer of 2016. A total of 8,795 mosquitoes, belonging to four species of three genera, and 1,300 midges were collected. The mosquito samples were identified on site according to their morphology, and the pooled samples were ground and centrifuged in the laboratory. The supernatant was incubated with mosquito tissue culture cells (C6/36) and mammalian cells (BHK-21) for virus isolation. The results indicated that 40% (3,540/8,795) were Anopheles sinensis, 30% (2,700/8,795) were Culex pipiens quinquefasciatus, and 29% (2,530/8,795) were Armigeres subbalbeatus...
October 19, 2017: Science China. Life Sciences
https://www.readbyqxmd.com/read/29057937/significance-of-ccl2-ccl5-and-ccr2-polymorphisms-for-adverse-prognosis-of-japanese-encephalitis-from-an-endemic-population-of-india
#19
Purvita Chowdhury, Siraj Ahmed Khan
Japanese encephalitis (JE) is a major contributor for viral encephalitis in Asia. Vaccination programme has limited success for largely populated JE endemic countries like India and disease exposure is unavoidable. Involvement of chemokines and its co-receptors for adverse prognosis of JE have been documented both in vitro and in vivo. Identification of the genetic predisposing factor for JE infection in humans is crucial but not yet established. Therefore, we investigated the association of single nucleotide polymorphisms (SNPs) in chemokines (CCL2 and CCL5) and its co-receptors (CCR2 and CCR5) with their protein level for JE...
October 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29050802/episode-of-kasabach-merritt-phenomenon-following-japanese-encephalitis-vaccination-case-report
#20
Xiaojie Yue, Xiong Zhao, Yefeng Dai, Qiang Shu
Kasabach-Merritt phenomenon (KMP) is a rare potentially life-threatening consumptive coagulopathy characterized by thrombocytopenia and hypofibrinogenemia occurring associated with the vascular tumors kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). A 10-month old male infant, diagnosed with KHE on his left leg, underwent a rapid increase of the lesion and severe thrombocytopenia, one day after the first dose of inactivated Japanese encephalitis (JE) vaccination. The episode of KMP was treated successfully by steroid...
October 16, 2017: Vaccine
keyword
keyword
43985
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"