keyword
MENU ▼
Read by QxMD icon Read
search

japanese encephalitis

keyword
https://www.readbyqxmd.com/read/27918946/toxicity-of-ar-curcumene-and-epi-%C3%AE-bisabolol-from-hedychium-larsenii-zingiberaceae-essential-oil-on-malaria-chikungunya-and-japanese-encephalitis-mosquito-vectors
#1
Mashael Marzouq AlShebly, Fatma Saeed AlQahtani, Marimuthu Govindarajan, Kasi Gopinath, Periasamy Vijayan, Giovanni Benelli
Mosquitoes act as vectors of key pathogens and parasites. Plant essential oils have been recognized as important sources of biopesticides, which do not induce resistance and have limited toxic effects on human health and non-target organisms. In this research, we evaluated the larvicidal and oviposition deterrence activity of Hedychium larsenii essential oil (EO) and its major compounds ar-curcumene and epi-β-bisabolol. Both molecules showed high toxicity against early third instars of Anopheles stephensi (LC50=10...
December 2, 2016: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/27903416/post-licensure-phase-iv-safety-study-of-a-live-attenuated-japanese-encephalitis-recombinant-vaccine-in-children-in-thailand
#2
Tawee Chotpitayasunondh, Pornpimol Pruekprasert, Thanyawee Puthanakit, Chitsanu Pancharoen, Auchara Tangsathapornpong, Peninnah Oberdorfer, Pope Kosalaraksa, Olarn Prommalikit, Suwimon Tangkittithaworn, Phirangkul Kerdpanich, Chonnamet Techasaensiri, Joanna Korejwo, Sunate Chuenkitmongkol, Guy Houillon
BACKGROUND: Japanese encephalitis is a mosquito-borne viral disease endemic in most countries in Asia. A recombinant live, attenuated Japanese encephalitis virus vaccine, JE-CV, is licensed in 14 countries, including Thailand, for the prevention of Japanese encephalitis in adults and children. METHODS: This was a prospective, phase IV, open-label, multicentre, safety study of JE-CV conducted from November 2013 to April 2015, to evaluate rare serious adverse events (AEs)...
November 28, 2016: Vaccine
https://www.readbyqxmd.com/read/27892528/sphingomyelin-generated-by-sphingomyelin-synthase-1-is-involved-in-attachment-and-infection-with-japanese-encephalitis-virus
#3
Makoto Taniguchi, Takafumi Tasaki, Hideaki Ninomiya, Yoshibumi Ueda, Koh-Ichi Kuremoto, Susumu Mitsutake, Yasuyuki Igarashi, Toshiro Okazaki, Tsutomu Takegami
Japanese encephalitis virus (JEV) is a mosquito-borne RNA virus which infects target cells via the envelope protein JEV-E. However, its cellular targets are largely unknown. To investigate the role of sphingomyelin (SM) in JEV infection, we utilized SM-deficient immortalized mouse embryonic fibroblasts (tMEF) established from SM synthase 1 (SMS1)/SMS2 double knockout mice. SMS deficiency significantly reduced both intracellular and extracellular JEV levels at 48 h after infection. Furthermore, after 15 min treatment with JEV, the early steps of JEV infection such as attachment and cell entry were also diminished in SMS-deficient tMEFs...
November 28, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27879539/clinically-mild-encephalitis-encephalopathy-with-a-reversible-splenial-lesion-accompanied-by-epstein-barr-virus-hemophagocytic-lymphohistiocytosis-a-case-report-and-review-of-the-literature
#4
Hiroshi Yamaguchi, Toshiaki Ishida, Takehito Yokoi, Tsukasa Tanaka, Azusa Maruyama, Hiroaki Nagase, Daiichiro Hasegawa, Ken-Ichi Imadome, Hiroki Takeda, Yoshiyuki Kosaka, Yoshiyuki Uetani
Central nervous system involvement in hemophagocytic lymphohistiocytosis (HLH) is associated with a poor outcome. For such patients, it is unknown whether more aggressive therapies, such as intrathecal methotrexate or hydrocortisone, are inevitably required. We present a very rare case of 3-year-old Japanese girl who developed mild encephalitis/encephalopathy with a reversible splenial lesion, accompanied by Epstein-Barr virus-associated HLH, and review previous similar reports. Our case and previous reports suggest that mild encephalitis/encephalopathy with a reversible splenial lesion accompanied by Epstein-Barr virus-associated HLH has a relatively good prognosis, even in the absence of intrathecal treatments...
November 22, 2016: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/27866611/facile-fabrication-of-eco-friendly-nano-mosquitocides-biophysical-characterization-and-effectiveness-on-neglected-tropical-mosquito-vectors
#5
Marimuthu Govindarajan, S L Hoti, Giovanni Benelli
Mosquito (Diptera: Culicidae) vectors are solely responsible for transmitting important diseases such as malaria, dengue, chikungunya, Japanese encephalitis, lymphatic filariasis and Zika virus. Eco-friendly control tools of Culicidae vectors are a priority. In this study, we proposed a facile fabrication process of poly-disperse and stable silver nanoparticles (Ag NPs) using a cheap leaf extract of Ichnocarpus frutescens (Apocyanaceae). Bio-reduced Ag NPs were characterized by UV-vis spectrophotometry, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction analysis (XRD), atomic force microscopy (AFM), scanning electron microscopy (SEM) and transmission electron microscopy (TEM)...
December 2016: Enzyme and Microbial Technology
https://www.readbyqxmd.com/read/27846060/immunogenicity-of-a-live-attenuated-chimeric-japanese-encephalitis-vaccine-as-a-booster-dose-after-primary-vaccination-with-live-attenuated-sa14-14-2-vaccine-a-phase-iv-study-in-thai-children
#6
Sirintip Sricharoenchai, Keswadee Lapphra, Sunate Chuenkitmongkol, Wanatpreeya Phongsamart, Alain Bouckenooghe, Orasri Wittawatmongkol, Supattra Rungmaitree, Kulkanya Chokephaibulkit
This single-group study investigated the immunogenicity and safety of a booster dose of the recently licensed live attenuated chimeric Japanese encephalitis vaccine in 50 healthy children (1-5 years old) who were primed with the live attenuated SA14-14-2 vaccine. A strong anamnestic response was induced 28 days post-booster: GMT, 9,144 (95% CI 7,365-11,353); and seroprotection rate, 49/49 (100%) children.
November 11, 2016: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27836006/mycoplasma-pneumoniae-associated-mild-encephalitis-encephalopathy-with-a-reversible-splenial-lesion-report-of-two-pediatric-cases-and-a-comprehensive-literature-review
#7
Norishi Ueda, Satoshi Minami, Manabu Akimoto
BACKGROUND: No literature review exists on Mycoplasma pneumoniae-associated mild encephalitis/encepharopathy with a reversible splenial lesion (MERS). METHODS: M.pneumoniae-associated MERS cases were searched till August 2016 using PubMed/Google for English/other-language publications and Ichushi ( http://www.jamas.or.jp/ ) for Japanese-language publications. Inclusion criteria were children fulfilling definition for encephalitis, M.pneumoniae infection, and neuroimaging showing hyperintensity in the splenium of the corpus callosum (SCC) alone (type I) or SCC/other brain areas (type II)...
November 11, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27834908/epitope-identification-and-application-for-diagnosis-of-duck-tembusu-virus-infections-in-ducks
#8
Chenxi Li, Junyan Liu, Wulin Shaozhou, Xiaofei Bai, Qingshan Zhang, Ronghong Hua, Jyung-Hurng Liu, Ming Liu, Yun Zhang
Duck Tembusu virus (DTMUV) causes substantial egg drop disease. DTMUV was first identified in China and rapidly spread to Malaysia and Thailand. The antigenicity of the DTMUV E protein has not yet been characterized. Here, we investigated antigenic sites on the E protein using the non-neutralizing monoclonal antibodies (mAbs) 1F3 and 1A5. Two minimal epitopes were mapped to (221)LD/NLPW(225) and (87)YAEYI(91) by using phage display and mutagenesis. DTMUV-positive duck sera reacted with the epitopes, thus indicating the importance of the minimal amino acids of the epitopes for antibody-epitope binding...
November 10, 2016: Viruses
https://www.readbyqxmd.com/read/27834337/a-novel-indirect-elisa-for-diagnosis-of-dengue-fever
#9
Rohan Narayan, Senthil Raja, Senthil Kumar, Mohana Sambasivam, Raja Jagadeesan, Kavita Arunagiri, Kaveri Krishnasamy, Gunasekaran Palani
BACKGROUND & OBJECTIVES: Dengue fever (DF) is associated with significant morbidity and mortality in the tropical and sub-tropical regions of the world. Since there are no effective antiviral drugs for treatment, clinicians often rely on the accurate diagnosis of dengue fever to begin supportive therapy at early stages of the illness. The objective of this study was to develop an in-house dengue virus serotype 2 (DENV-2) non-structural protein- 5 (NS5) based indirect ELISA. METHODS: DENV-2 was raised in Vero cells and the viral proteins were separated and subsequently the NS5 protein was eluted...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27828763/serological-prevalence-against-japanese-encephalitis-virus-serocomplex-flaviviruses-in-commensal-and-field-rodents-in-south-china
#10
Shao-Wei Chen, Li-Na Jiang, Xue-Shan Zhong, Xue-Yan Zheng, Shu-Juan Ma, Yi-Quan Xiong, Jun-Hua Zhou, Xing Li, Xue-Mei Ke, Wen Zhou, Qing Chen
BACKGROUND: Japanese encephalitis caused by Japanese encephalitis virus (JEV) is an endemic zoonotic disease of high public health importance in the Asian Pacific region. The aim of this study was to investigate the presence of JEV infection in commensal and field rodents in South China. MATERIALS AND METHODS: RNA copies of JEV were detected in brain samples of rodents using real-time RT-PCR. Detection of serum against JEV-reactive antibodies was performed using indirect enzyme-linked immunosorbent assay and microneutralization test...
December 2016: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/27824100/identification-of-a-new-broadly-cross-reactive-epitope-within-domain-iii-of-the-duck-tembusu-virus-e-protein
#11
Chenxi Li, Xiaofei Bai, Runze Meng, Wulin Shaozhou, Qingshan Zhang, Ronghong Hua, Jyung-Hurng Liu, Ming Liu, Yun Zhang
In 2010, a pathogenic flavivirus termed duck Tembusu virus (DTMUV) caused widespread outbreak of egg-drop syndrome in domesticated ducks in China. Although the glycoprotein E of DTMUV is an important structural component of the virus, the B-cell epitopes of this protein remains uncharacterized. Using phage display and mutagenesis, we identified a minimal B-cell epitope, (374)EXE/DPPFG(380), that mediates binding to a nonneutralizing monoclonal antibody. DTMUV-positive duck serum reacted with the epitope, and amino acid substitutions revealed the specific amino acids that are essential for antibody binding...
November 8, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27821699/epidemiological-features-of-japanese-encephalitis-in-taiwan-from-2000-to-2014
#12
Yu-Kang Chang, Hsiao-Ling Chang, Ho-Sheng Wu, Kow-Tong Chen
The incidence of Japanese encephalitis (JE) decreased sharply after the national vaccination program was implemented in Taiwan in 1968. However, cases of JE still occur. The purpose of this study was to assess the epidemiology and vaccination policy for JE in Taiwan. We analyzed the data on JE cases reported to the Taiwan Centers for Disease Control (Taiwan CDC) between 2000 and 2014. During the 15-year study period, a total of 4,474 cases were reported to the Taiwan CDC. Of these, 379 (8.5%) were classified as confirmed cases, and 4,095 (91...
November 7, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27815383/persistence-of-wild-type-japanese-encephalitis-virus-strains-cross-neutralization-five-years-following-je-cv-immunization
#13
Emmanuel Feroldi, Mark Boaz, Sutee Yoksan, Kulkanya Chokephaibulkit, Usa Thisyakorn, Chitsanu Pancharoen, Céline Monfredo, Alain Bouckenooghe
BACKGROUND:  The live-attenuated Japanese encephalitis (JE) vaccine (JE-CV; IMOJEV(®)) induces a protective response in children. A shift in circulating JE virus strains suggests that a genotype shift phenomenon may occur throughout South-East Asia. We assessed the neutralization of wild-type (WT) JE virus isolates at distal time points post-vaccination. METHODS:  We analysed serum samples from a subset of 47 children who had received a JE-CV booster after an inactivated JE vaccine primary immunization...
November 3, 2016: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27800692/waiting-in-the-wings-the-potential-of-mosquito-transmitted-flaviviruses-to-emerge
#14
Duncan R Smith
The sudden dramatic emergence of the mosquito transmitted flavivirus Zika virus has bought to the world's attention a relatively obscure virus that was previously only known to specialist researchers. The genus Flavivirus of the family Flaviviridae contains a number of well-known mosquito transmitted human pathogenic viruses including the dengue, yellow fever, Japanese encephalitis and West Nile viruses. However, the genus also contains a number of lesser known human pathogenic viruses transmitted by mosquitoes including Wesselsbron virus, Ilheus virus, St...
November 1, 2016: Critical Reviews in Microbiology
https://www.readbyqxmd.com/read/27799646/seasonality-of-viral-encephalitis-and-associated-environmental-risk-factors-in-son-la-and-thai-binh-provinces-in-vietnam-from-2004-to-2013
#15
Hu Suk Lee, Hung Nguyen-Viet, Mihye Lee, Phuc Pham Duc, Delia Grace
In Vietnam, Japanese encephalitis virus accounts for 12-71% of viral encephalitis (VE) cases followed by enteroviruses and dengue virus among identified pathogens. This study is the first attempt to evaluate the seasonality of VE and associated environmental risk factors in two provinces from 2004 to 2013 using a seasonal trend-decomposition procedure based on loess regression and negative binomial regression models. We found seasonality with a peak of VE in August and June in Son La and Thai Binh, respectively...
October 31, 2016: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/27799502/refusal-of-recommended-travel-related-vaccines-among-u-s-international-travellers-in-global-travepinet
#16
Sara M Lammert, Sowmya R Rao, Emily S Jentes, Jessica K Fairley, Stefanie Erskine, Allison T Walker, Stefan H Hagmann, Mark J Sotir, Edward T Ryan, Regina C LaRocque
BACKGROUND: International travellers are at risk of travel-related, vaccine-preventable diseases. More data are needed on the proportion of travellers who refuse vaccines during a pre-travel health consultation and their reasons for refusing vaccines. METHODS: We analyzed data on travellers seen for a pre-travel health consultation from July 2012 through June 2014 in the Global TravEpiNet (GTEN) consortium. Providers were required to indicate one of three reasons for a traveller refusing a recommended vaccine: (1) cost concerns, (2) safety concerns or (3) not concerned with the illness...
July 2016: Journal of Travel Medicine
https://www.readbyqxmd.com/read/27795474/an-ecological-survey-of-mosquitoes-and-the-distribution-of-japanese-encephalitis-virus-in-ishikawa-prefecture-japan-between-2010-and-2014
#17
Manabu Murakami, Kiyoe Hori, Yoko Kitagawa, Yosaburo Oikawa, Kiyoshi Kamimura, Tsutomu Takagemi
Japanese encephalitis virus (JEV) is a flavivirus and is responsible for over 30,000 annual cases of encephalitis worldwide, with a mortality rate of approximately 30%. Therefore, it is important to check the distribution of JEV in fields, although recently, the number of Japanese encephalitis (JE) cases has been approximately five per year in Japan. We report the seasonal dynamics of mosquitoes between 2010 and 2014 in Ishikawa Prefecture, Japan. We collected 39,308 female adult mosquitoes, 98.2% of which were classified as Culex tritaeniorhynchus Giles...
October 31, 2016: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27795473/dengue-associated-acute-encephalitis-syndrome-cases-in-son-la-province-vietnam-in-2014
#18
Mya Myat Ngwe Tun, Rohitha V Muthugala, Nguyen Thi Thu Thuy, Pham Hoai Linh Ly, Le Thi Hien Thu, Dang Thi Dinh, Nguyen Viet Hoang, Le Thi Quynh Mai, Meng Ling Moi, Corazon C Buerano, Kouichi Morita, Futoshi Hasebe
Acute encephalitis syndrome (AES) is associated with high morbidity and mortality, and affects both children and adults. The main etiologic agent is Japanese encephalitis virus (JEV), however there are also reports on Dengue virus (DENV) encephalitis cases. The objectives of this paper were to determine the proportion of encephalitic patients due to JEV during the 2014 outbreak in Son La Province in Vietnam and to find the association of DENV in non-JEV viral encephalitis cases. Out of 90 patients, 6 (6.7%) were positive for anti-JEV IgM, 5 (5...
October 31, 2016: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/27776548/fast-type-i-interferon-response-protects-astrocytes-from-flavivirus-infection-and-virus-induced-cytopathic-effects
#19
Richard Lindqvist, Filip Mundt, Jonathan D Gilthorpe, Silke Wölfel, Nelson O Gekara, Andrea Kröger, Anna K Överby
BACKGROUND: Neurotropic flaviviruses such as tick-borne encephalitis virus (TBEV), Japanese encephalitis virus (JEV), West Nile virus (WNV), and Zika virus (ZIKV) are causative agents of severe brain-related diseases including meningitis, encephalitis, and microcephaly. We have previously shown that local type I interferon response within the central nervous system (CNS) is involved in the protection of mice against tick-borne flavivirus infection. However, the cells responsible for mounting this protective response are not defined...
October 24, 2016: Journal of Neuroinflammation
https://www.readbyqxmd.com/read/27774302/inference-of-japanese-encephalitis-virus-ecological-and-evolutionary-dynamics-from-passive-and-active-virus-surveillance
#20
Truc T Pham, Shengli Meng, Yan Sun, Wenli Lv, Justin Bahl
A comprehensive monitoring strategy is vital for tracking the spread of mosquito-borne Japanese encephalitis virus (JEV), the leading cause of viral encephalitis in Asia. Virus detection consists of passive surveillance of primarily humans and swine, and/or active surveillance in mosquitoes, which may be a valuable proxy in providing insights into ecological processes underlying the spread and persistence of JEV. However, it has not been well characterized whether passive surveillance alone can capture the circulating genetic diversity to make reasonable inferences...
January 2016: Virus Evolution
keyword
keyword
43985
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"