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https://www.readbyqxmd.com/read/29922531/ureteritis-cystica-an-unusual-presentation-in-an-otherwise-healthy-female
#1
Jai D Parekh, John Iguidbashian, Venkata Andukuri
A 23-year-old, previously healthy female presented with lower abdominal pain and mildly elevated creatinine one month following a right ureter stent for non-specific ureteral thickening causing obstruction. On admission, computed tomography (CT) revealed moderate hydronephrosis of the left kidney that would require stent placement as well. During stent placement, it was noted that the gross appearance of the ureters resembled ureteritis cystica. Biopsies were taken and showed signs of chronic inflammatory changes consistent with this diagnosis...
April 17, 2018: Curēus
https://www.readbyqxmd.com/read/29913175/implementation-of-an-urogynecology-specific-enhanced-recovery-after-surgery-eras-pathway
#2
Charelle M Carter-Brooks, Angela L Du, Kristine M Ruppert, Anna L Romanova, Halina M Zyczynski
OBJECTIVES: ERAS protocols were developed for colorectal surgery to hasten post-op recovery. Variations of the protocol are being adopted for gynecologic procedures despite limited population and procedure-specific outcome data. Our objective was to evaluate if implementation of an ERAS pathway would facilitate reduced length of admission in an urogynecology population. MATERIALS AND METHODS: In this retrospective analysis of patients undergoing pelvic floor reconstructive surgery by 7 female pelvic medicine and reconstructive surgeons we compared same day discharge, length of admission and post-op complications before and after implementation of an ERAS pathway at a tertiary-care hospital...
June 15, 2018: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29910547/diagnosing-catheter-associated-urinary-tract-infection-in-critically-ill-patients-do-the-guidelines-help
#3
REVIEW
Sai Saran, Namrata S Rao, Afzal Azim
Catheter-associated urinary tract infection (CAUTI) is the leading cause of hospital-acquired infections in hospitalized patients in medical and surgical wards, but it is still commonly underdiagnosed in critically ill patients despite a higher device usage rate. The most commonly employed diagnostic criteria for such diagnosis come from the Infectious Disease Society of America and Centers for Disease Control and Prevention National Health Safety Network surveillance definition. It is surprising that no separate diagnostic criteria of CAUTI exist, for the critically ill patients - though these patients are of a different class of patients' altogether, due to decreased immunity, existence on multiple organ supports, and invasive lines, and an inability to communicate with a clinician...
May 2018: Indian Journal of Critical Care Medicine
https://www.readbyqxmd.com/read/29908216/complications-of-delivery-among-mothers-with-spina-bifida
#4
Courtney L Shepard, Phyllis L Yan, Stephanie J Kielb, Daniela A Wittmann, Elisabeth H Quint, Kate H Kraft, John M Hollingsworth
OBJECTIVE: To determine rates and types of peripartum morbidity among delivering women with spina bifida (SB) compared to those without SB. The rates of pregnancy and delivery among women with SB have been significantly increasing. Current knowledge of peripartum outcomes for these women is limited. METHODS: Using 2004-2013 National Inpatient Sample data, we identified all hospitalizations for delivery, distinguishing between women with and without SB. Using a code-based algorithm, we determined whether a complication occurred during the hospitalization...
June 13, 2018: Urology
https://www.readbyqxmd.com/read/29904444/the-impact-of-nutritional-status-and-complete-blood-count-parameters-on-clinical-outcome-in-geriatric-critically-ill-patients
#5
Abdulkerim Yildiz, Ali Yigit, Ali Ramazan Benli
Background: The geriatric population in intensive care units (ICUs) has recently increased. The aim of this study was to analyse the impact of initial complete blood count (CBC)-related parameters and nutritional status on morbidity and mortality in geriatric ICU patients. Methods: A retrospective analysis was made of geriatric patients admitted to our tertiary adult ICU for 1 year. Patients with a length of stay (LOS) of < 48 h, with hematological malignancy or age < 65 years age were excluded from the study...
July 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29900824/an-implementation-of-next-generation-sequencing-for-prevention-and-diagnosis-of-urinary-tract-infection-in-urology
#6
Vladimir Mouraviev, Michael McDonald
INTRODUCTION: The changing face of current infection phenotypes from planktonic to biofilm type has been developed implicating bacterial biofilms in recurrent infection. To date, no specific medical treatment exists to specifically target biofilms in the human host. Similarly, the identification of a biofilm has relied upon the analysis of tissue samples with electron microscopy or DNA identification with polymerase chain reaction (PCR) and sequencing. Standard culture and sensitivity test is not able to detect a presence of biofilms...
June 2018: Canadian Journal of Urology
https://www.readbyqxmd.com/read/29891004/treatable-causes-of-fever-among-children-under-five-years-in-a-seasonal-malaria-transmission-area-in-burkina-faso
#7
Francois Kiemde, Marc Christian Tahita, Palpouguini Lompo, Toussaint Rouamba, Athanase M Some, Halidou Tinto, Petra F Mens, Henk D F H Schallig, Michael Boele van Hensbroek
BACKGROUND: Fever remains a major public health problem. In Burkina Faso, more than half of febrile children are considered not to be infected by malaria. This study prospectively assessed probable (treatable) causes of fever in Burkinabe children. METHODS: A prospective study was conducted among febrile children (≥37.5 °C) under 5 years of age presenting at four health facilities and one referral hospital in rural Burkina Faso. From each participant, blood was collected for malaria microscopy and culture, urine for dipstick testing and culturing if tested positive for leucocytes and nitrite, stool for rotavirus/adenovirus testing, culture and parasitology, and a nasopharyngeal swab for culture...
May 31, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29888145/a-community-based-iot-personalized-wireless-healthcare-solution-trial
#8
Philip A Catherwood, David Steele, Mike Little, Stephen Mccomb, James Mclaughlin
This paper presents an advanced Internet of Things point-of-care bio-fluid analyzer; a LoRa/Bluetooth-enabled electronic reader for biomedical strip-based diagnostics system for personalized monitoring. We undertake test simulations (technology trial without patient subjects) to demonstrate potential of long-range analysis, using a disposable test 'key' and companion Android app to form a diagnostic platform suitable for remote point-of-care screening for urinary tract infection (UTI). The 868 MHz LoRaWAN-enabled personalized monitor demonstrated sound potential with UTI test results being correctly diagnosed and transmitted to a remote secure cloud server in every case...
2018: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/29885657/infectious-disease-burden-and-antibiotic-prescribing-in-primary-care-in-israel
#9
Marcelo Low, Ronit Almog, Ran D Balicer, Nicky Liberman, Raul Raz, Avi Peretz, Orna Nitzan
BACKGROUND: Antibiotics are frequently prescribed at many of the visits to primary care clinics, often for conditions for which they provide no benefit, including viral respiratory tract infections. OBJECTIVES: The aim was to evaluate primary care visits due to infectious diseases, and to estimate antibiotic prescribing and antibiotic dispensing by pharmacies. METHODS: Diagnosis of infectious disease, antibiotic prescribing and dispensing data at the individual patient level were extracted for 2015 from Clalit Health Services' electronic medical records and linked to determine the condition for which the antimicrobial was prescribed...
June 9, 2018: Annals of Clinical Microbiology and Antimicrobials
https://www.readbyqxmd.com/read/29881220/sacral-chordoma-a-review-of-literature
#10
REVIEW
S Pillai, S Govender
Chordoma is a rare malignant tumor with predilection for the sacrum. A favorable outcome depends on early diagnosis and surgical excision with tumor free margins. Aim: To review the incidence and prevalence of sacral chordoma and the appropriate surgical management and formulate a criteria for early diagnosis. Materials and methods: Thirty eight articles on the subject of sacral chordoma and extrapolated data of clinical and surgical significance. Results: The commonest presenting feature in patients with sacral chordoma was lower back pain which was worse on sitting and up to a third of these patients had associated urinary tract infections, constipation or symptoms of disc herniation...
June 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29881186/timing-of-complications-following-posterior-cervical-fusion
#11
J Mason DePasse, Wesley Durand, Adam E M Eltorai, Mark A Palumbo, Alan H Daniels
Study design: Retrospective cohort study. Objective: To characterize the timing of complications after posterior cervical fusion. Summary of background data: Understanding the expected timing of postoperative complications facilitates early diagnosis of potential adverse events and is important for optimizing postoperative care. Though studies have examined the incidence of complications after posterior cervical fusion, no study has characterized the timing of these complications...
June 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29880703/neonatal-circumcision-and-urinary-tract-infections-in-infants-with-hydronephrosis
#12
Jonathan S Ellison, Geolani W Dy, Benjamin C Fu, Sarah K Holt, John L Gore, Paul A Merguerian
BACKGROUND: Boys with urinary tract abnormalities may derive a greater benefit from newborn circumcision for prevention of urinary tract infection (UTI) than the general population. However, the effect of newborn circumcision on UTI is not well characterized across the etiological spectrum of hydronephrosis. We hypothesized that boys with an early diagnosis of hydronephrosis who undergo newborn circumcision will have reduced rates of UTI. METHODS: The MarketScan data set, an employer-based claims database, was used to identify boys with hydronephrosis or hydronephrosis-related diagnoses within the first 30 days of life...
June 7, 2018: Pediatrics
https://www.readbyqxmd.com/read/29875036/delayed-diagnosis-of-primary-vesicoureteral-reflux-in-children-with-recurrent-urinary-tract-infections-diagnostic-approach-and-renal-outcomes
#13
Çağla Serpil Doğan, Nevin Semerci Koyun, Gülşah Kaya Aksoy, Bülent Çekiç, Murat Savaş, Elif Çomak
OBJECTIVE: In this study, we aimed to assess renal outcomes of delayed diagnosis of dilating primary vesicoureteral reflux (VUR) following recurrent febrile urinary tract infections (fUTIs) and its diagnostic imaging procedures. MATERIAL AND METHODS: The medical records of patients who underwent ultrasonography (US), non- acute dimercaptosuccinic acid (Tc-99mDMSA) scintigraphy and voiding cystourethrography (VCUG), and who were older than 2 years at the time of VUR diagnosis were retrospectively reviewed...
May 31, 2018: Turkish Journal of Urology
https://www.readbyqxmd.com/read/29871019/bacterial-infections-in-acute-on-chronic-liver-failure
#14
Lingling Yang, Tianzhou Wu, Jiang Li, Jun Li
Acute-on-chronic liver failure (ACLF) is a newly recognized clinical syndrome characterized by preexisting chronic liver disease or cirrhosis with organ failure and high 28-day mortality (50-90%). Bacterial infections (BIs) play pivotal roles in the development and progression of ACLF either as a main precipitating event or a specific complication. The main organisms isolated as triggering ACLF are Gram-positive bacteria, followed by Gram-negative bacteria. Spontaneous bacterial peritonitis, pneumonia, urinary tract infections, and skin infections are prevalent infections that trigger and complicate ACLF...
May 2018: Seminars in Liver Disease
https://www.readbyqxmd.com/read/29848518/a-3-month-old-infant-with-atypical-kawasaki-disease
#15
Nichkamol Lertamornkitti, Anchalee Wangjirapan
We report a 3-month-old girl who presented with high-grade fever for 3 days. Her initial physical examination was normal. Investigation showed abnormal white cells in her urine. She was diagnosed with a urinary tract infection and received an antibiotic for 1 day. After that, she developed a generalised maculopapular rash over her body. An adverse drug reaction from the antibiotic was suspected, and the patient was referred to our hospital. On admission, she still had fever and was irritable. She was diagnosed with sepsis and given another broad-spectrum antibiotic for 2 days...
May 30, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29804355/-diagnosis-and-treatment-of-bacterial-infection-in-patients-with-end-stage-liver-disease
#16
W W Luo, D Z Zhang
Patients with end-stage liver disease have an increased risk of developing bacterial infections, resulting in an increase in the number of hospitalizations and medical expenses, a decline in the quality of life of patients, and an increased fatality rate. Bacterial infections in patients with end-stage liver disease is mainly due to the falling off the body's immune response causing respiratory infections, spontaneous bacterial peritonitis, urinary tract infections and gastrointestinal infections. The diagnosis of bacterial infection is more challenging because the occurrence of infection shows no typical symptoms and signs...
January 20, 2018: Zhonghua Gan Zang Bing za Zhi, Zhonghua Ganzangbing Zazhi, Chinese Journal of Hepatology
https://www.readbyqxmd.com/read/29803667/relationships-between-enteral-nutrition-facts-and-urinary-stones-in-a-cohort-of-pediatric-patients-in-rehabilitation-from-severe-acquired-brain-injury
#17
Marco Pozzi, Federica Locatelli, Sara Galbiati, Elena Beretta, Carla Carnovale, Emilio Clementi, Sandra Strazzer
BACKGROUND & AIMS: Urolithiasis affects pediatric patients with severe acquired brain injury, in whom the role of several clinical variables and of the presence and composition of enteral nutrition has not been investigated. METHODS: Retrospective chart review on 371 pediatric patients with severe acquired brain injury. We used an essential electronic database to check the association between stones and enteral feeding. We then picked at random paper clinical records until we collected 20 and 20 complete records for patients with/without stones, not matched...
May 14, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29797011/xantogranulomatous-pyeloneprhritis-in-children
#18
REVIEW
Cinta Sangüesa Nebot, Sara Picó Aliaga, Agustín Serrano Durbá, María José Roca
Xanthogranulomatous pyelonephritis (XPN) is an unusual and severe form of chronic inflammatory lesion of the kidney, characterised by the destruction of the renal parenchyma and the presence of multinucleated giant cells and lipid-laden macrophages, inflammatory infiltration and intensive renal fibrosis. There are a few cases in the literature which describe the disease in children. The pathomechanism of XPN is poorly understood. Renal obstruction with concomitant urinary tract infection is the most commonly associated pathological finding...
May 23, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29792287/safety-tolerability-pharmacokinetics-and-pharmacodynamics-of-glpg1690-a-novel-autotaxin-inhibitor-to-treat-idiopathic-pulmonary-fibrosis-flora-a-phase-2a-randomised-placebo-controlled-trial
#19
Toby M Maher, Ellen M van der Aar, Olivier Van de Steen, Lisa Allamassey, Julie Desrivot, Sonia Dupont, Liesbeth Fagard, Paul Ford, Ann Fieuw, Wim Wuyts
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) causes irreversible loss of lung function. People with IPF have increased concentrations of autotaxin in lung tissue and lysophosphatidic acid (LPA) in bronchoalveolar lavage fluid and exhaled condensate. GLPG1690 (Galapagos, Mechelen, Belgium) is a novel, potent, selective autotaxin inhibitor with good oral exposure. We explored the effects of GLPG1690 in patients with IPF. METHODS: This was a randomised, double-blind, placebo-controlled phase 2a study done in 17 centres in Italy, Ukraine and the UK...
May 18, 2018: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/29790623/the-analysis-of-microbial-spectrum-and-antibiotic-resistance-of-uropathogens-isolated-from-patients-with-urinary-stones
#20
Dong Chen, Yuyan Zhang, Jian Huang, Xiongfa Liang, Tao Zeng, Chuangxin Lan, Xiaolu Duan, Zhijian Zhao, Guohua Zeng, Hans-Göran Tiselius, Xiaogang Lu, Wenqi Wu
PURPOSE: The characteristics and resistance patterns of urine bacteriology in patients with urinary tract stones have not been extensively studied. This study aims to investigate the microbial spectrum and antibiotic resistance of uropathogens isolated from urinary tract infections in patients with urinary stones and provide a basis for appropriate antimicrobial treatments. METHODS: The results of positive bladder midstream urine cultures and their antimicrobial susceptibility were retrospectively analysed from hospitalised patients with diagnosis of urinary calculi and urinary tract infections between January 2010 and December 2015...
May 23, 2018: International Journal of Clinical Practice
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