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https://www.readbyqxmd.com/read/28217699/the-female-urinary-microbiota-urinary-health-and-common-urinary-disorders
#1
REVIEW
Linda Brubaker, Alan J Wolfe
This review provides the clinical context and updated information regarding the female urinary microbiota (FUM), a resident microbial community within the female bladder of many adult women. Microbial communities have variability and distinct characteristics in health, as well as during community disruption (dysbiosis). Information concerning characteristics of the FUM in health and disease is emerging. Sufficient data confirms that the microbes that compose the FUM are not contaminants and are cultivatable under appropriate conditions...
January 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28217396/predictive-model-of-length-of-stay-and-discharge-destination-in-neuroscience-admissions
#2
M M Stecker, M Stecker, J Falotico
BACKGROUND: The purpose of this study was to try and determine the best predictors of hospital length of stay and discharge destination in patients admitted to a neuroscience service. METHODS: Valid data was collected for 170 patients. Variables included age, gender, location prior to admission, principle diagnosis, various physiological measurements upon admission, comorbidity, independence in various activities of daily living prior to admission, length of stay, and disposition upon discharge...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28215176/the-comparison-the-serum-strem1-levels-between-children-with-upper-and-lower-uti
#3
Samileh Noorbakhsh, Fahime Ehsanipour, Vida Zarabi, Zahra Movahedi, Nahid Rahimzadeh
: Back ground: UTI is a common and important clinical problem in Iranian children which is often difficult on clinical grounds. Distinguishing the upper UTI from lower UTI is very important for clinician. The aim of this study was to determine the usefulness of serum STREM-1 level in patients with UTI to find out if it can use for distinguishing upper UTI from lower UTI or not. METHODS: In this prospective cross sectional study (2010-2011) we compared the serum level of STREM-1 (pg...
February 16, 2017: Current Pediatric Reviews
https://www.readbyqxmd.com/read/28210838/urinary-ngal-deficiency-in-recurrent-urinary-tract-infections
#4
Catherine S Forster, Kathryn Johnson, Viral Patel, Rebecca Wax, Nancy Rodig, Jonathan Barasch, Richard Bachur, Richard S Lee
INTRODUCTION: Children with recurrent urinary tract infections (rUTI) often show no identifiable cause of their infections. Neutrophil gelatinase-associated lipocalin (NGAL) is known to be upregulated within the uroepithelium and kidney of patients with UTI and exhibits a localized bacteriostatic effect through iron chelation. We hypothesize that some patients with rUTI without an identifiable cause of their recurrent infections have locally deficient NGAL production. We therefore explored whether a lack of NGAL production may be a factor in the pathogenesis of rUTI...
February 16, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28210573/emphysematous-pyelonephritis-in-a-transplanted-kidney
#5
Cristiano Claudino Oliveira, Paula Dalsoglio Garcia, Rosa Marlene Viero
Emphysematous pyelonephritis is a rare infection characterized by necrosis and gas accumulation in the renal parenchyma, adjacent tissues, and/or urinary collecting system. This entity is rarely reported in transplanted kidneys. Computed tomography imaging is necessary for diagnosis and risk classification. The authors described the case of a 58-year-old man who underwent a kidney transplant and presented sepsis from a urinary tract infection. An abdominal tomography showed some characteristics of emphysematous pyelonephritis associated with an abscess...
October 2016: Autopsy & case reports
https://www.readbyqxmd.com/read/28208916/delirium-in-parkinson-s-disease-a-cocktail-diagnosis
#6
Robin George Manappallil
Mental disturbances have been described in patients with Parkinson's Disease (PD). Of these, the common conditions are delirium and psychosis. Delirium has been attributed to change of environment, especially hospital stay and infections; while psychosis is due to drugs like dopamine agonists. This is a case of a 75-year-old male, on levodopa therapy for PD, who presented with delirium and ended up with a cocktail diagnosis: Cryptococcal meningitis, Hashimoto's Encephalopathy (HE), Urinary tract infection with acute renal failure, Uremic encephalopathy and Levodopa induced psychosis...
December 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28203451/case-report-a-rare-cause-of-complicated-urinary-tract-infection-in-a-woman-with-herlyn-werner-wunderlich-syndrome
#7
Jun-Li Tsai, Shang-Feng Tsai
INTRODUCTION: Urinary tract infection is a common disease in the general population. However, in patients with frequent urinary tract infection, it is important to determine any treatable cause to avoid recurrence. CASE PRESENTATION: Herlyn-Werner-Wunderlich syndrome or OHVIRA syndrome is a very rare congenital anomaly with uterus didelphys, obstructed hemivagina, and ipsilateral renal agenesis. The earliest presentation of this syndrome is hematocolpos that develops during menstruation and results in dysmenorrhea and a pelvic mass shortly after menarche...
November 2016: Iranian Red Crescent Medical Journal
https://www.readbyqxmd.com/read/28199403/comparison-of-microbiological-diagnosis-of-urinary-tract-infection-in-young-children-by-routine-health-service-laboratories-and-a-research-laboratory-diagnostic-cohort-study
#8
Kate Birnie, Alastair D Hay, Mandy Wootton, Robin Howe, Alasdair MacGowan, Penny Whiting, Michael Lawton, Brendan Delaney, Harriet Downing, Jan Dudley, William Hollingworth, Catherine Lisles, Paul Little, Kathryn O'Brien, Timothy Pickles, Kate Rumsby, Emma Thomas-Jones, Judith Van der Voort, Cherry-Ann Waldron, Kim Harman, Kerenza Hood, Christopher C Butler, Jonathan A C Sterne
OBJECTIVES: To compare the validity of diagnosis of urinary tract infection (UTI) through urine culture between samples processed in routine health service laboratories and those processed in a research laboratory. POPULATION AND METHODS: We conducted a prospective diagnostic cohort study in 4808 acutely ill children aged <5 years attending UK primary health care. UTI, defined as pure/predominant growth ≥105 CFU/mL of a uropathogen (the reference standard), was diagnosed at routine health service laboratories and a central research laboratory by culture of urine samples...
2017: PloS One
https://www.readbyqxmd.com/read/28195912/visualization-of-posttraumatic-splenosis-on-chemokine-receptor-cxcr4-targeted-pet-ct
#9
Thorsten Derlin, Hans-Jürgen Wester, Frank M Bengel, Katja Hueper
The C-X-C motif chemokine receptor 4 (CXCR4) is expressed by a variety of inflammatory and malignant cells. We report the case of a 54-year-old woman with recurrent urinary tract infection who underwent a Ga-pentixafor PET/CT for detection of occult infectious foci. As a secondary finding, multiple CXCR4 abdominal lesions could be seen, consistent with the diagnosis of long-known posttraumatic splenosis. It is important to be aware that CXCR4-directed imaging may identify splenic tissue based on the presence of inflammatory cells and that both benign and malignant cells may show CXCR4 expression to avoid misinterpretation...
February 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28169964/bladder-cancer-risk-factors-diagnosis-and-management
#10
Kristen Burns Farling
Bladder cancer is the most common genitourinary cancer in the United States. Symptoms of bladder cancer mimic those of a urinary tract infection, which can delay timely diagnosis. Because of the high rate of bladder cancer, it is likely advanced practice registered nurses will be responsible for the care of patients with bladder cancer. This article reviews the signs and symptoms of bladder cancer along with management options to safely care for this patient population.
March 7, 2017: Nurse Practitioner
https://www.readbyqxmd.com/read/28169298/the-value-of-delta-neutrophil-index-in-young-infants-with-febrile-urinary-tract-infection
#11
Jung Won Lee, Seong Heon Kim, Se Jin Park, Keum Hwa Lee, Jae Hyon Park, Andreas Kronbichler, Michael Eisenhut, Ji Hong Kim, Jong Wook Lee, Jae Il Shin
Delta neutrophil index (DNI) is the fraction of circulating immature granulocytes, which reflects severe bacterial infections and septic condition but has not been studied in urinary tract infection (UTI). Here, we evaluated the value of DNI in predicting acute pyelonephritis (APN) or vesicoureteral reflux (VUR) using the data of 288 patients. Conventional inflammatory markers (white blood cell [WBC] count, erythrocyte sedimentation rate [ESR], C-reactive protein [CRP]), and DNI were measured. WBC, CRP, ESR and DNI were higher in APN than in lower UTI (p < 0...
February 7, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28169046/ileal-neobladder-an-important-cause-of-non-anion-gap-metabolic-acidosis
#12
Jesse W St Clair, Matthew L Wong
BACKGROUND: The differential diagnosis for a non-anion gap metabolic acidosis is probably less well known than the differential diagnosis for an anion gap metabolic acidosis. One etiology of a non-anion gap acidosis is the consequence of ileal neobladder urinary diversion for the treatment of bladder cancer. CASE REPORT: We present a case of a patient with an ileal neobladder with a severe non-anion gap metabolic acidosis caused by a urinary tract infection and ureteroenterostomy...
February 3, 2017: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28166740/delineation-of-cystinuria-in-saudi-arabia-a-case-series
#13
Abdulrahman Obaid, Marwan Nashabat, Khalid Al Fakeeh, Abdullah T Al Qahtani, Majid Alfadhel
BACKGROUND: Cystinuria is an inherited metabolic disease that is caused by defects in two genes, SLC3A1 and SLC7A9, which result in a renal reabsorptive defect of cystine and other dibasic amino acids, including ornithine, arginine, and lysine. Patients usually present with recurrent renal calculi and may develop renal impairment. Medical management includes high fluid intake and chelating agents. To the best of our knowledge, this is the first study describing cystinuria in Saudi Arabia...
February 6, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28161350/triggered-urine-interleukin-6-correlates-to-severity-of-symptoms-in-non-febrile-lower-urinary-tract-infections
#14
Fredrik Sundén, Daniel Butler, Björn Wullt
PURPOSE: Objective diagnosis of symptomatic urinary tract infections (UTI) in patients prone to asymptomatic bacteriuria (ABU) is compromised by the already present local host responses and the positive urine culture. We investigated Interleukin-6 (IL-6) as a biomarker for non-febrile UTI severity, and diagnostic thresholds for IL-6, IL8 and neutrophils in differentiating between ABU and UTI. METHODS: Patients with residual urine and neurogenic bladders due to spinal lesions included in a long term E...
February 1, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28154883/-urinary-tract-infections-in-children
#15
E Lellig, M Apfelbeck, J Straub, A Karl, S Tritschler, C G Stief, M Riccabona
Urinary tract infections (UTI) are the most common bacterial infections in children. The symptoms are not very specific and range from abdominal pain, poor feeding to nocturnal urinary incontinence. The technique of collecting urine plays an important role for securing the diagnosis. The best way to obtain urine in non-toilet-trained children is catheterization or suprapubic bladder aspiration. In toilet-trained children midstream urine is an acceptable alternative after cleaning the foreskin or labia. In the case of an infection a prompt empirical antibiotic therapy is necessary to reduce the risk of parenchymal scarring of the kidneys...
February 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28153592/recurrent-urinary-tract-infections-in-a-female-child-with-polydactyly-and-a-pelvic-mass-consider-the-mckusick-kaufman-syndrome
#16
Ahmed Adam, Julian Hellig, Nasreen Mahomed, Lindsay Lambie
A 3-year-old female child presented with a history of recurrent urinary tract infections. On general examination, polydactyly and a pelvic mass were present. An imperforate hymen was also documented on vaginal inspection. Further inquiry, revealed a positive history of parental consanguinity. A magnetic resonance imaging study defined a hydrometrocolpos responsible for an obstructive cause of the recurrent urinary tract infections. In view of the above, a diagnosis of McKusick-Kaufman syndrome was made. Formal surgical repair of the imperforate hymen with hydrometrocolpos drainage resulted in complete symptom resolution...
January 30, 2017: Urology
https://www.readbyqxmd.com/read/28146187/-factors-associated-with-extended-spectrum-betalactamases-producing-organisms-among-patients-with-urinary-tract-infections-a-prospective-cohort-study
#17
Cristián Avilés, Pablo Betancour, Carmen Luz Velasco, Rodrigo Godoy, Elizabeth Barthel, Felipe Martínez
BACKGROUND: Urinary tract infections (UTIs) caused by extended-spectrum betalactamases (ESBL) are an increasingly common problem. AIM: To develop an association model to allow an early detection of ESBL-producing microorganisms. METHODS: A prospective observational cohort study was undertaken among patients admitted with a diagnosis of culture-proven UTI to the Internal Medicine Ward of the Hospital Naval Almirante Nef between February and November, 2011...
December 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28140454/geriatric-infectious-diseases-current-concepts-on-diagnosis-and-management
#18
Thomas T Yoshikawa, Dean C Norman
New information on infectious diseases in older adults has become available in the past 20 years. In this review, in-depth discussions on the general problem of geriatric infectious diseases (epidemiology, pathogenesis, age-related host defenses, clinical manifestations, diagnostic approach); diagnosis and management of bacterial pneumonia, urinary tract infection, and Clostridium difficile infection; and the unique challenges of diagnosing and managing infections in a long-term care setting are presented.
January 31, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28131056/simultaneous-determination-of-creatinine-and-acetate-by-capillary-electrophoresis-with-contactless-conductivity-detector-as-a-feasible-approach-for-urinary-tract-infection-diagnosis
#19
Wojciech Grochocki, Michał J Markuszewski, Joselito P Quirino
Urinary tract infection (UTI) is one of the most common bacterial infection in human but its diagnosis is difficult. Metabolomic studies with nuclear magnetic resonance of urine have shown that acetic acid/creatinine ratio may be used for early UTI diagnosis. Here, a method for simultaneous determination of acetate and creatinine by capillary zone electrophoresis with contactless conductivity detector was developed for the first time. The separation was with 40mM MES and 20mM l-histidine as a background solution...
January 22, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28128910/current-practice-of-antibiotic-utilization-for-renal-colic-in-the-emergency-room
#20
Bryan Hinck, Benjamin Larson, Shubha De, Manoj Monga
INTRODUCTION: Urinalysis (UA) in the emergency setting for patients with nephrolithiasis produces potentially confusing results leading to treatment of presumed urinary tract infections (UTIs). Our objective was to evaluate the use of antibiotics in patients with nephrolithiasis in a large network of emergency departments (EDs). METHODS: A retrospective analysis of all ED visits associated with an ICD-9 diagnosis of nephrolithiasis and a CT scan between 2010 and 2013 was performed...
January 27, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
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