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Diagnosis uti

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https://www.readbyqxmd.com/read/29036204/metabolic-phenotyping-in-the-mouse-model-of-urinary-tract-infection-shows-that-3-hydroxybutyrate-in-plasma-is-associated-with-infection
#1
Pei Han, Yong Huang, Yumin Xie, Wu Yang, Yaoyao Wang, Wenying Xiang, Peter J Hylands, Cristina Legido-Quigley
Urinary tract infection is one of the most common bacterial infections worldwide. Current diagnosis of urinary tract infection chiefly relies on its clinical presentation, urine dipstick tests and urine culture. Small molecules found in bio-fluids related with both infection and recovery would facilitate diagnosis and management of UTI. Mass spectrometry-based fingerprinting of plasma and urine at 3 time points, pre-infection (t = -24h), infection (t = 24h) and post 3-day treatment (t = 112h), were acquired in the following four groups: mice which were healthy, infected but not treated, infected and treated with ciprofloxacin, and infected and treated with Relinqing® granules (n = 6 per group)...
2017: PloS One
https://www.readbyqxmd.com/read/29035239/diagnosis-of-trichomoniasis-in-male-patients-on-performing-nested-polymerase-chain-reaction
#2
T Mutlu Yar, Mehmet Karakuş, Seray Töz, Aysun Bay Karabulut, Yusuf Özbel, Metin Atambay
OBJECTIVE: Trichomoniasis is a parasitic infection that occurs with the settlement of Trichomonas vaginalis in female and male urinary and reproductive tracts. This infection is generally asymptomatic in males, and males are thought to be a carrier for the transmission of infection. In this study, our aim was to detect trichomoniasis using nested polymerase chain reaction among males who were referred to a hospital with suspected urinary tract infection. METHODS: Urine samples were collected from 138 male patients between 18 and 50 years of age who were referred with suspected urinary system infection to the Urology Outpatient Clinic at Malatya University Medical Center Malatya between December 2013 and May 2014...
September 2017: Türkiye Parazitolojii Dergisi
https://www.readbyqxmd.com/read/29032850/impact-of-penicillin-allergy-on-time-to-first-dose-of-antimicrobial-therapy-and-clinical-outcomes
#3
Erin L Conway, Ken Lin, John A Sellick, Kari Kurtzhalts, James Carbo, Michael C Ott, Kari A Mergenhagen
PURPOSE: The objective of this study was to evaluate the impact of a listed penicillin allergy on the time to first dose of antibiotic in a Veterans Affairs hospital. Additional clinical outcomes of patients with penicillin allergies were compared with those of patients without a penicillin allergy. METHODS: A retrospective chart review of veterans admitted through the emergency department with a diagnosis of pneumonia, urinary tract infection, bacteremia, and sepsis from January 2006 to December 2015 was conducted...
October 9, 2017: Clinical Therapeutics
https://www.readbyqxmd.com/read/29030135/staphylococcus-saprophyticus-which-%C3%AE-lactam
#4
Hélène Pailhoriès, Viviane Cassisa, Rachel Chenouard, Marie Kempf, Matthieu Eveillard, Carole Lemarié
OBJECTIVES: Staphylococcus saprophyticus (SS) is resistant to molecules often used in empiric treatment of urinary-tract infections (UTI). The adequacy of antimicrobial treatments prescribed for UTI due to SS is not usually questioned. We described the epidemiology of those infections and assessed the susceptibility of SS to ceftriaxone and amoxicillin-clavulanic acid. METHODS: From November 2014 to July 2016, the methicillin susceptible SS (MSSS) isolated from clinical samples were included...
October 10, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29026632/salmonella-oranienburg-haemorrhagic-cystitis-in-an-immunocompetent-young-male
#5
Jiasian Teh, Mark Quinlan, Damien Bolton
Introduction. Non-typhoidal salmonella (NTS) bacteriuria is extremely rare. Haemorrhagic cystitis is defined by urinary symptoms including haematuria, frequency, urgency and dysuria. Reports of haemorrhagic cystitis caused by NTS are exceptionally uncommon, especially in immunocompetent, young, male patients. Case presentation. A 27-year-old male with no past medical history presented to the Emergency Department with a 24 h history of visible haematuria having returned five days earlier from a five month trip across South America...
August 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29023894/perineal-groove-in-female-infants-a-case-series-and-literature-review
#6
Maria Garcia-Palacios, Roberto Mendez-Gallart, Jorge Cortizo-Vazquez, Pablo Rodriguez-Barca, Elina Estevez-Martinez, Adolfo Bautista-Casasnovas
BACKGROUND: Perineal groove is a rare congenital malformation that is unknown to many clinicians and is often misdiagnosed. Although it may be self-resolving during childhood, this nonepithelized mucous membrane can pose the risk of local irritation and infection, particularly urinary tract infection. METHODS: A retrospective study of female infants diagnosed with a perineal groove was performed, demographic characteristics and clinical features were analyzed, and a photographic review was conducted...
October 11, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/29020720/pyelonephritis-can-lead-to-life-threatening-complications
#7
Declan B Keenan, Declan M O'Rourke, Aisling E Courtney
Acute pyelonephritis is suggested by the constellation of fever (temperature ≥ 38.5° C), flank pain (typically unilateral), nausea and vomiting, and costovertebral angle tenderness. Complaints typical of lower UTI are variably present. The severity of symptoms ranges from a mild pyrexial illness to life-threatening sepsis. The diagnosis of acute pyelonephritis should be suspected on the basis of the history and clinical examination. If the urine dipstick is negative for nitrites and leukocyte esterase this does not exclude the diagnosis, but it should prompt a re-evaluation of the clinical features and consideration of other potential diagnoses...
February 2017: Practitioner
https://www.readbyqxmd.com/read/29018014/elizabethkingia-meningoseptica-emerging-multidrug-resistance-in-a-nosocomial-pathogen
#8
Sairam Raghavan, Biji Thomas, B A Shastry
A 46-year-old male patient presented with complaints of burning micturition for 2 days. Initial history, physical examination and laboratory investigations were consistent with the diagnosis of congestive cardiac failure (CCF) and concomitant urinary tract infection. CCF was treated with diuretics and a urine culture/sensitivity (C/S) was sent which returned growing Elizabethkingia meningoseptica resistant to all tested drugs. Intravenous cefotaxime which had been started empirically 3 days earlier was withheld at this point, and a repeat urine C/S was sent revealing resistance to all tested drugs (including reserved drugs) barring minocycline...
October 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29017265/antibiotic-overconsumption-in-pregnant-women-with-urinary-tract-symptoms-in-uganda
#9
Musa Sekikubo, Karolina Hedman, Florence Mirembe, Annelie Brauner
Background: Urinary tract infections (UTIs) are one of the most common bacterial infections in women. During pregnancy physiological changes, like frequency, mimic UTI symptoms, and therefore bacteriological cultures are needed to confirm the diagnosis. However, in developing countries antibiotic therapy is commonly initiated without culture confirmation. Methods: We investigated the prevalence of bacteriuria among pregnant women with and without UTI symptoms in Uganda...
August 15, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28987639/mismatch-between-suspected-pyelonephritis-and-microbiological-diagnosis-a-cohort-study-from-a-uk-teaching-hospital
#10
Laura Shallcross, Kate Gaskell, Andrew Fox-Lewis, Malin Bergstrom, Mahdad Noursadeghi
Urinary tract infection (UTI) syndromes are a common reason for empirical antibiotic prescribing in the Emergency Department (ED). We investigated the role of microbiological culture and urinalysis in the diagnosis of pyelonephritis by extracting data on 105 patients with a clinical diagnosis of pyelonephritis at a London teaching hospital. 96/102 patients were treated empirically with intravenous antibiotics but only 55/100 patients who were sampled had microbiological evidence of infection in urine and/or blood...
October 4, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28986090/urinary-tract-infection-in-children-diagnosis-treatment-imaging-comparison-of-current-guidelines
#11
REVIEW
M Okarska-Napierała, A Wasilewska, E Kuchar
BACKGROUND AND OBJECTIVE: Urinary tract infection (UTI) is a frequent disorder of childhood, yet the proper approach for a child with UTI is still a matter of controversy. The objective of this study was to critically compare current guidelines for the diagnosis and management of UTI in children, in light of new scientific data. METHODS: An analysis was performed of the guidelines from: American Academy of Pediatrics (AAP), National Institute for Health and Care Excellence (NICE), Italian Society of Pediatric Nephrology, Canadian Paediatric Society (CPS), Polish Society of Pediatric Nephrology, and European Association of Urology (EAU)/European Society for Pediatric Urology (ESPU)...
September 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28980274/neutrophil-gelatinase-associated-lipocalin-a-biomarker-for-early-diagnosis-of-urinary-tract-infections-in-infants
#12
Grażyna Krzemień, Małgorzata Pańczyk-Tomaszewska, Dominika Adamczuk, Iwona Kotuła, Urszula Demkow, Agnieszka Szmigielska
Early diagnosis of urinary tract infection (UTI) is challenging in infants due to unspecific symptoms, difficulty in urine collection and possible contamination. The aim of this study was to assesses the usefulness of serum and urine neutrophil gelatinase-associated lipocalin (sNGAL and uNGAL, respectively) in the diagnosis of febrile and non-febrile UTI in infants. This prospective observational study enrolled 66 infants with the first episode of UTI and 18 healthy controls. At the time of enrollment, sNGAL, uNGAL, urinalysis, urine culture, white blood cell count (WBC), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalcitonin (PCT), and serum creatinine (sCr) were assessed...
October 5, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28978905/early-progression-of-xanthogranulomatous-pyelonephritis-in-children-might-be-dependent-on-vimentin-expression
#13
Danuta Ostalska-Nowicka, Katarzyna Mackowiak-Lewandowicz, Aneta Konwerska, Jacek Zachwieja
BACKGROUND Xanthogranulomatous pyelonephritis (XP) is an extremely rare, severe, atypical form of chronic renal parenchymal inflammation accompanied by hydronephrosis and/or urolithiasis. The pathomechanism of XP is not yet fully understood. Microscopically, XP is indicated by the presence of multinucleated giant cells and lipid-laden macrophages, as well as inflammatory infiltration and intensive renal fibrosis. The lipid accumulation in kidney parenchyma may be secondary to the altered flow of low-density lipoprotein (LDL)-derived cholesterol particles inside the affected cells...
October 5, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28978286/the-clinical-diagnosis-and-management-of-urinary-tract-infections-in-children-and-adolescents
#14
Lindsey Korbel, Marianella Howell, John David Spencer
Urinary tract infections (UTI) are one of the most common and serious bacterial infections encountered by paediatricians and primary care physicians. Although the diagnosis and management of UTI appear simplistic, they remain among the most contentious issues in paediatrics. In part, UTI controversies stem from the absence of classic clinical symptoms, inappropriate urine specimen collection, modified urinary tract imaging recommendations, and diverse treatment and prevention strategies. Recently published guidelines and large clinical trials have attempted to clarify UTI diagnostic and management strategies...
October 5, 2017: Paediatrics and International Child Health
https://www.readbyqxmd.com/read/28975420/diagnosis-and-management-of-bladder-bowel-dysfunction-in-children-with-urinary-tract-infections-a-position-statement-from-the-international-children-s-continence-society
#15
Stephen Yang, Michael E Chua, Stuart Bauer, Anne Wright, Per Brandström, Piet Hoebeke, Søren Rittig, Mario De Gennaro, Elizabeth Jackson, Eliane Fonseca, Anka Nieuwhof-Leppink, Paul Austin
BACKGROUND: We present a consensus view from the International Children's Continence Society (ICCS) on the evaluation and management of bladder bowel dysfunction (BBD) in children with urinary tract infection (UTI). The statement aims to highlight the importance of BBD in the development and recurrence of childhood UTI and its management to reduce its associated morbidity and sequelae. METHODS: A systematic literature search was done on PubMed, Embase, and Scopus databases until August 15, 2016...
October 3, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28973215/urinary-tract-infection
#16
REVIEW
Kalpana Gupta, Larissa Grigoryan, Barbara Trautner
Urinary tract infections (UTIs) are common in both inpatient and outpatient settings. This article provides an evidence-based, clinically relevant overview of management of UTIs, including screening, diagnosis, treatment, and prevention. Conditions covered include acute cystitis (both uncomplicated and complicated), catheter-associated UTI, and asymptomatic bacteriuria in both women and men.
October 3, 2017: Annals of Internal Medicine
https://www.readbyqxmd.com/read/28969594/identification-of-compound-heterozygous-patients-with-primary-hyperoxaluria-type-1-clinical-evaluations-and-in-silico-investigations
#17
Houda Kanoun, Faiçal Jarraya, Bayen Maalej, Amina Lahiani, Hichem Mahfoudh, Fatma Makni, Jamil Hachicha, Faiza Fakhfakh
BACKGROUND: Primary hyperoxaluria type 1 (PH1) is an autosomal recessive inherited disorder of glyoxylate metabolism in which excessive oxalates are formed by the liver and excreted by the kidneys. Calcium oxalate crystallizes in the urine, leading to urolithiasis, nephrocalcinosis, and consequent renal failure if treatment is not initiated promptly. Mutations in the AGXT gene which encodes the hepatic peroxisomal enzyme alanine:glyoxylate aminotransferase are responsible of PH1. In the present work, we aimed to analyze AGXT gene and in silico investigations performed in four patients with PH1 among two non consanguineous families...
October 2, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28962814/nosocomial-infections-in-the-neurointensive-care-unit
#18
REVIEW
Katharina Maria Busl
Infectious complications in the neurointensive care unit (neuro-ICU) are common, including pneumonia, urinary tract infection, bloodstream infection, and intracranial infection. The neuro-ICU population poses a specific challenge in the diagnosis of infections, because of the high incidence of fever in acutely brain-injured patients. Furthermore, susceptibility to infections is likely enhanced by brain-injury (induced immune modulation). This article reviews the concept of brain injury-induced immune modulation, and summarizes available data and knowledge on nosocomial meningitis and ventriculitis, and systemic infectious complications in patients with traumatic brain injury, ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage, and status epilepticus...
November 2017: Neurologic Clinics
https://www.readbyqxmd.com/read/28961815/quality-of-antibiotic-prescribing-of-swiss-primary-care-physicians-with-high-prescription-rates-a-nationwide-survey
#19
Dominik Glinz, Selene Leon Reyes, Ramon Saccilotto, Andreas F Widmer, Andreas Zeller, Heiner C Bucher, Lars G Hemkens
Objectives: To assess the quality of antibiotic prescribing of Swiss primary care physicians with high prescription rates. Methods: In January 2015, we mailed a structured questionnaire to 2900 primary care physicians in Switzerland. They were included in a nationwide pragmatic randomized controlled trial on routine antibiotic prescription monitoring and feedback based on health insurance claims data. We asked them to record the diagnosis and antibiotic treatment for 44 consecutive patients with the most common conditions associated with antibiotic prescribing in primary care...
August 24, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28958067/an-intra-aortic-floating-metastatic-malignancy-of-unknown-primary-origin
#20
Yoshinori Kuroda, Tetsuro Uchida, Jun Hayashi, Mitsuaki Sadahiro
A 69-year-old man with sudden strong back pain was transported to our hospital by ambulance. The computed tomography scan revealed an intra-aortic floating mass with a stalk arising from the descending aortic wall, which was thought to be a thrombus. The floating mass displayed the characteristics of a thrombus rather than a neoplastic tumour on magnetic resonance imaging scan. Under extracorporeal circulation, the descending aorta was cut open, and the mass was resected. Subsequently, a stent graft was placed to cover the abnormal aortic intima to prevent recurrent thrombus formation...
August 29, 2017: European Journal of Cardio-thoracic Surgery
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