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https://www.readbyqxmd.com/read/28209187/perceptions-and-experiences-of-pregnant-women-about-routine-hiv-testing-and-counselling-in-ghimbi-town-ethiopia-a-qualitative-study
#1
Israel Mitiku, Adamu Addissie, Mitike Molla
BACKGROUND: Ethiopia has implemented routine HIV testing and counselling using a provider initiated HIV testing ('opt-out' approach) to achieve high coverage of testing and prevention of mother-to-child transmission of HIV. However, women's perceptions and experiences with this approach have not been well studied. We conducted a qualitative study to explore pregnant women's perceptions and experiences of routine HIV testing and counselling in Ghimbi town, Ethiopia, in May 2013. In-depth interviews were held with 28 women tested for HIV at antenatal clinics (ANC), as well as four health workers involved in routine HIV testing and counselling...
February 16, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28207749/determinants-of-first-trimester-attendance-at-antenatal-care-clinics-in-the-amazon-region-of-peru-a-case-control-study
#2
Nora Moore, Brittany Blouin, Hugo Razuri, Martin Casapia, Theresa W Gyorkos
OBJECTIVE: To identify determinants which influence the timing of the first antenatal care (ANC) visit in pregnant women. DESIGN: Retrospective matched nested case-control study. SETTING: Two health centres, Belén and 6 de Octubre, in the Peruvian Amazon. POPULATION: All pregnant women who had attended ANC during the years 2010, 2011, and 2012. METHODS: All cases (819 women initiating ANC in their first trimester) were selected from ANC registries from 2010 to 2012...
2017: PloS One
https://www.readbyqxmd.com/read/28199373/prevalence-of-maternal-hiv-infection-and-knowledge-on-mother-to-child-transmission-of-hiv-and-its-prevention-among-antenatal-care-attendees-in-a-rural-area-in-northwest-cameroon
#3
Carlson-Babila Sama, Vitalis F Feteh, Maxime Tindong, John T Tanyi, Nestor Mbinkar Bihle, Fru F Angwafo
BACKGROUND: In 2010, an estimated 141 new HIV infections occurred per day in Cameroon and reports suggest an upsurge of these rates by 2020 if current trends continue. Mother-to-child transmission (MTCT) of HIV is a major public health challenge, and maternal knowledge on HIV transmission during pregnancy and its prevention is important in curtailing paediatric HIV acquisition. OBJECTIVES: We aimed at establishing the prevalence of maternal HIV infection as well as assessing knowledge on HIV, MTCT and prevention of MTCT (PMTCT) of HIV among pregnant women in a rural area of Cameroon...
2017: PloS One
https://www.readbyqxmd.com/read/28197346/allogeneic-transplant-in-elane-and-mefv-mutation-positive-severe-cyclic-neutropenia-review-of-prognostic-factors-for-secondary-severe-events
#4
Onyemaechi N Okolo, Emmanuel Katsanis, Seongseok Yun, Candace Y Reveles, Faiz Anwer
Objective and Importance. Cyclic neutropenia (CyN) is a rare autosomal dominant inherited disorder due to the mutation ELANE primarily affecting bone marrow stem cells and is characterized by recurrent neutropenia every 2 to 4 weeks. Symptoms vary from benign to severe, including death. Postulations on the cause of wide spectrum in symptom presentation include the possibility of other genetic mutations, such as MEFV. Recommended treatment for CyN is G-CSF to keep ANC higher to minimize risk of infection. Case...
2017: Case Reports in Hematology
https://www.readbyqxmd.com/read/28192301/dynamic-interaction-between-actin-and-nesprin2-maintain-the-cell-nucleus-in-a-prestressed-state
#5
Abhishek Kumar, G V Shivashankar
Mechanical coupling between the nucleus and the cytoskeleton is indispensable for direct force transduction from the extra cellular matrix (ECM) to the chromatin. Although this physical coupling has been shown to be crucial for nuclear positioning and its function, the quantification of nuclear-cytoskeleton interaction has been lacking. In this paper, using various quantitative fluorescence spectroscopy techniques, we investigate the nature of this connection. High-resolution 3D imaging shows that nesprin2G forms short linear structures along actin stress fibers (ASFs) in the apical region of the nucleus...
November 11, 2016: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/28191845/self-assembled-nanoconstructs-modified-with-amplified-aptamers-inhibited-tumor-growth-and-retinal-vascular-hyperpermeability-via-vegf-capturing
#6
Jihyun Lee, Byung Joo Lee, Yeong Mi Lee, Hansoo Park, Jeong Hun Kim, Won Jong Kim
Here, nanoconstructs consisting of a DNA-amplified aptamer with a biocompatible polymer backbone for capturing target biomolecules are presented. First, the polymer-DNA nanoconstructs were prepared by hybridization of two complementary single-stranded DNAs that were each conjugated to a dextran polymer backbone. The designed polymer-DNA amplified aptamer nanoconstructs (PA-aNCs) were then prepared by utilizing polymer-DNA nanoconstructs conjugated with an aptamer (PA-NCs) using a rolling circle amplification reaction to amplify the aptamer...
February 13, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28184381/a-multicenter-longitudinal-interventional-double-blind-randomized-clinical-trial-in-hematopoietic-cell-transplant-recipients-residing-in-remote-areas-lessons-learned-from-the-late-cytomegalovirus-prevention-trial
#7
Louise E Kimball, Terry Stevens-Ayers, Margaret L Green, Hu Xie, Mary E D Flowers, Keith R Jerome, Renee LeBlanc, Christi Dahlgren, W Garrett Nichols, Roy F Chemaly, G Papanicolaou, Michael Boeckh
PURPOSE: The logistics of conducting double-blinded phase III clinical trials with participants residing in remote locations are complex. Here we describe the implementation of an interventional trial for the prevention of late cytomegalovirus (CMV) disease in hematopoietic cell transplantation (HCT) subjects in a long-term follow-up environment. METHODS: A total of 184 subjects at risk for late CMV disease surviving 80 days following allogeneic HCT were randomized to receive six months of valganciclovir or placebo...
December 15, 2016: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/28181013/factors-associated-with-receiving-late-hiv-testing-among-women-delivering-at-hung-vuong-hospital-ho-chi-minh-city-vietnam-2014
#8
V N Khuu, V T Nguyen, N K Hills, T P Hau, D P Nguyen, V T Nhung, P T Lan, D B Brickley
HIV testing during pregnancy facilitates timely antiretroviral treatment for HIV-positive women. This study identifies reasons for late HIV testing among pregnant women delivering at a hospital in Ho Chi Minh City. We conducted a case-control study in which 160 cases were women who were tested for HIV late (i.e., at labor and delivery) and 160 controls were women who were tested during antenatal care (ANC). In multivariable logistic regression analysis, six variables were associated with late HIV testing: age less than 30 years, nine or fewer years of education, working as a homemaker or worker/farmer, living 20 km or more from the hospital, having received ANC at a private clinic/hospital only, and not believing that HIV testing is important during pregnancy...
February 8, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28177299/development-of-an-improved-wearable-device-for-core-body-temperature-monitoring-based-on-the-dual-heat-flux-principle
#9
Jingjie Feng, Congcong Zhou, Cheng He, Yuan Li, Xuesong Ye
In this paper, a miniaturized wearable core body temperature (CBT) monitoring system based on the dual heat flux (DHF) principle was developed. By interspersing calcium carbonate powder in PolyDimethylsiloxane (PDMS), a reformative heat transfer medium was produced to reduce the thermal equilibrium time. Besides, a least mean square (LMS) algorithm based active noise cancellation (ANC) method was adopted to diminish the impact of ambient temperature fluctuations. Theoretical analyses, finite element simulation, experiments on a hot plate and human volunteers were performed...
February 8, 2017: Physiological Measurement
https://www.readbyqxmd.com/read/28176933/synthesis-characterization-and-cytocompatibility-of-potential-cockle-shell-aragonite-nanocrystals-for-osteoporosis-therapy-and-hormonal-delivery
#10
Alhaji Zubair Jaji, Md Zuki Bin Abu Bakar, Rozi Mahmud, Mohamad Yusof Loqman, Mohamad Noor Mohamad Hezmee, Tijani Isa, Fu Wenliang, Nahidah Ibrahim Hammadi
Calcium carbonate is a porous inorganic nanomaterial with huge potential in biomedical applications and controlled drug delivery. This study aimed at evaluating the physicochemical properties and in vitro efficacy and safety of cockle shell aragonite calcium carbonate nanocrystals (ANC) as a potential therapeutic and hormonal delivery vehicle for osteoporosis management. Free and human recombinant parathyroid hormone 1-34 (PTH 1-34)-loaded cockle shell aragonite calcium carbonate nanocrystals (PTH-ANC) were synthesized and evaluated using standard procedures...
2017: Nanotechnology, Science and Applications
https://www.readbyqxmd.com/read/28174219/inequality-trends-in-maternal-health-services-for-young-ghanaian-women-with-childbirth-history-between-2003-and-2014
#11
Benedict Oppong Asamoah, Anette Agardh
OBJECTIVE: To achieve universal coverage of reproductive healthcare and drastic reduction in maternal mortality, adequate attention and resources should be given to young women. This study therefore aimed to examine the inequality trends in the use of antenatal care (ANC) services and skilled birth attendance (SBA) within a subgroup of Ghanaian women aged 15-24 years between 2003 and 2014. DESIGN: This is a cross-sectional study that used data from the Ghana Demographic and Health Surveys (DHS) 2003, 2008 and 2014...
February 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28173687/distribution-and-determinants-of-low-birth-weight-in-developing-countries
#12
Rashidul Alam Mahumud, Marufa Sultana, Abdur Razzaque Sarker
Objectives: Low birth weight (LBW) is a major public health concern, especially in developing countries, and is frequently related to child morbidity and mortality. This study aimed to identify key determinants that influence the prevalence of LBW in selected developing countries. Methods: Secondary data analysis was conducted using 10 recent Demography and Health Surveys from developing countries based on the availability of the required information for the years 2010 to 2013...
January 2017: Journal of Preventive Medicine and Public Health, Yebang Ŭihakhoe Chi
https://www.readbyqxmd.com/read/28168052/dietary-diversity-is-not-associated-with-haematological-status-of-pregnant-women-resident-in-rural-areas-of-northern-ghana
#13
Mahama Saaka, Jeremiah Oladele, Asamoah Larbi, Irmgard Hoeschle-Zeledon
Background. Information regarding how dietary diversity is related to haematological status of the pregnant women in rural areas of Northern Ghana is limited. This study therefore evaluated maternal dietary intake and how it relates to the nutritional status of pregnant women belonging to different socioeconomic conditions in Northern Ghana. Methods. This study was cross-sectional in design involving 400 pregnant women. Midupper arm circumference (MUAC) and anaemia status were used to assess the nutritional status of pregnant women...
2017: Journal of Nutrition and Metabolism
https://www.readbyqxmd.com/read/28168042/coinfection-with-schistosoma-haematobium-and-plasmodium-falciparum-and-anaemia-severity-among-pregnant-women-in-munyenge-mount-cameroon-area-a-cross-sectional-study
#14
Judith K Anchang-Kimbi, Dillys Mansoh Elad, Gemain Taiwe Sotoing, Eric Akum Achidi
Background. Malaria and urogenital schistosomiasis are coendemic in Mount Cameroon Area. This study investigated the prevalence of S. haematobium, P. falciparum, and coinfections and their effect on anaemia in pregnancy. Methods. Pregnant women reporting for antenatal care (ANC) clinic visit in Munyenge were enrolled. S. haematobium and P. falciparum infections were determined by urine filtration and microscopy, respectively. Haemoglobin (Hb) levels were measured using haemoglobinometer. Of 250 women, 46.8%, 39...
2017: Journal of Parasitology Research
https://www.readbyqxmd.com/read/28167427/feasibility-of-using-demolition-waste-as-an-alternative-heavy-metal-immobilising-agent
#15
Seelawut Damrongsiri
Demolition waste consisting of cement paste, lightweight concrete and bricks is a worthless material generated by a growing city. However, research suggests that it may be applied as an alternative heavy metal immobilising agent. The diverse characteristics of demolition waste were examined. Cadmium was selected as there presentative heavy metal to investigate demolition waste adsorption capacity. The solid-liquid distribution coefficients (Kd) were observed. The adsorption isotherms were applied to investigate adsorption characteristics...
February 2, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28161046/is-surface-water-acidification-a-serious-regional-issue-in-china
#16
Qian Yu, Ting Zhang, Zhenglin Cheng, Bin Zhao, Jan Mulder, Thorjørn Larssen, Shuxiao Wang, Lei Duan
Acidic deposition used to cause severe surface water acidification in Europe and the North America, but no damage of surface water acidification was reported under continuous heavy acid deposition in China. We present the first detailed study on regional surface water acidification in southern and northeastern China based on a survey of 255 forested headwater streams, which were investigated during 2010-2015 to explore the status and mechanism of surface water acidification. South China has a subtropical climate with high acid deposition, whereas northeast China is located in a cold temperature zone with relatively low acid deposition...
February 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28159851/regional-differences-in-usage-of-antenatal-care-and-safe-delivery-services-in-indonesia-findings-from-a-nationally-representative-survey
#17
Vrijesh Tripathi, Rajvir Singh
BACKGROUND: Indonesia has shown a nominal increase in antenatal care (ANC) coverage from 93% to 96% in the Indonesia Demographic Health Survey (IDHS)-2012. This is high but for a comprehensive assessment of maternal health coverage in Indonesia, safe delivery services need to be assessed in conjunction with ANC coverage. MATERIALS AND METHODS: The study uses survey data from the IDHS-2012 that was conducted among women aged 15-49 years who gave birth during the past 3 years preceding the survey...
February 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28152938/evaluation-of-leukocytosis-benign-or-malignant
#18
Shuko Lee, Paromita Datta
: 245 Background: Hematologists frequently evaluate patients with leukocytosis to differentiate between benign and malignant causes. The objective of this quality improvement project was to identify risk factors for malignant leukocytosis. METHODS: A retrospective analysis of 1,330 consults in ALM VA Outpatient Hematology Clinic between 1/1/2011 and 2/22/2015 was performed. 147 patients referred for evaluation of leukocytosis were included in this study. The following data was collected: sex, age, race, ethnicity, BMI, tobacco use, total WBC, tempo of leukocytosis (constant vs intermittent), Hg level, plt count, ANC, ALC, AMC, AEC, ABC, laboratory tests performed during work-up, final diagnosis (primary hematologic malignancy vs secondary causes)...
March 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28150498/flavonoid-metabolites-in-human-urine-during-blueberry-anthocyanin-intake
#19
Wilhelmina Kalt, Jane E McDonald, Yan Liu, Sherry A E Fillmore
The human health benefits of anthocyanins (Anc) and other flavonoids are widely recognized. However the flavonoid-based urinary metabolites arising in vivo after Anc intake are not well described. Human (n=17) urine was collected while blueberry juice (BJ) was consumed daily for 28 d and once after a 7 d washout. MS/MS scanning of 664 urine samples for 18 parent Anc (PAnc) and 42 predicted Anc metabolites (AncM) yielded 371 products (i.e. MS/MS x retention time (RT)). Flavonoid-based AncM, which were likely underestimated, were almost 20-times more abundant than PAnc...
February 2, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28143611/the-effectiveness-of-introducing-group-prenatal-care-gpc-in-selected-health-facilities-in-a-district-of-bangladesh-study-protocol
#20
Marufa Sultana, Rashidul Alam Mahumud, Nausad Ali, Sayem Ahmed, Ziaul Islam, Jahangir A M Khan, Abdur Razzaque Sarker
BACKGROUND: Despite high rates of antenatal care and relatively good access to health facilities, maternal and neonatal mortality remain high in Bangladesh. There is an immediate need for implementation of evidence-based, cost-effective interventions to improve maternal and neonatal health outcomes. The aim of the study is to assess the effect of the intervention namely Group Prenatal Care (GPC) on utilization of standard number of antenatal care, post natal care including skilled birth attendance and institutional deliveries instead of usual care...
January 31, 2017: BMC Pregnancy and Childbirth
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