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"Decision analysis"

Renata Jędrkiewicz, Stefan Tsakovski, Aurore Lavenu, Jacek Namieśnik, Marek Tobiszewski
Novel methodology for grouping and ranking with application of self-organizing maps and multicriteria decision analysis is presented. The dataset consists of 22 objects that are analytical procedures applied to furan determination in food samples. They are described by 10 variables, referred to their analytical performance, environmental and economic aspects. Multivariate statistics analysis allows to limit the amount of input data for ranking analysis. Assessment results show that the most beneficial procedures are based on microextraction techniques with GC-MS final determination...
February 1, 2018: Talanta
B Godskesen, M Hauschild, H-J Albrechtsen, M Rygaard
Utilities in larger cities have to make complex decisions planning future investments in urban water infrastructure. Changes are driven by physical water stress or political targets for environmental water flows e.g. through the implementation of the European water framework directive. To include these environmental, economic and social sustainability dimensions we introduce a novel multi-criteria assessment method for evaluation of water supply technologies. The method is presented and demonstrated for four alternatives for water supply based on groundwater, rain- & stormwater or seawater developed for augmenting Copenhagen's current groundwater based water supply...
November 10, 2017: Science of the Total Environment
Amirfarhang Miresmaeili, Mohammad Basafa, Reza Mahvelati Shamsabadi, Nasrin Farhadian, Abbas Moghymbeigi, Vahid Mollabashi
OBJECTIVES: The aim of this study was to assess difficulty of treatment of palatally-displaced canines (PDC) according to experts' opinion using CBCT data and to determine a cut-off point for extraction versus forced eruption. SUBJECTS AND METHODS: Seven CBCT variables of thirty PDC cases were measured with Dolphin 3D software. In addition to measurements of each case, nine 3D and 2D views were prepared on one page and uploaded on the website (
November 5, 2017: International Orthodontics
Nicholas Kusnezov, Emmanuel D Eisenstein, John C Dunn, Aaron J Wey, David R Peterson, Brian R Waterman
PURPOSE: To provide further guidance on the optimal decision between anterior cruciate ligament (ACL) graft removal versus retention in the setting of septic arthritis following reconstruction using an expected value decision analysis. METHODS: A systematic review and expected value decision analysis and sensitivity analyses were performed to quantify the clinical decision. A decision tree was created with 5 outcomes of interest: nonoperative complications, revision surgery, early reoperation, late reoperation, and "well...
November 6, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
Rebecca J Hart, Michelle D Stevenson, Michael J Smith, A Scott LaJoie, Keith Cross
Importance: Influenza is a significant public health burden, causing morbidity and mortality in children, yet vaccination rates remain low. Vaccination in the pediatric emergency department (PED) setting may be beneficial but, to date, has not been proven to be cost-effective. Objective: To compare the cost-effectiveness of 4 strategies for PED-based influenza vaccine: offering vaccine to all patients, only to patients younger than 5 years, only to high-risk patients (all ages), or to no patients...
November 6, 2017: JAMA Pediatrics
Vladica Ristić, Marija Maksin, Marina Nenković-Riznić, Jelena Basarić
The process of making decisions on sustainable development and construction begins in spatial and urban planning when defining the suitability of using land for sustainable construction in a protected area (PA) and its immediate and regional surroundings. The aim of this research is to propose and assess a model for evaluating land-use suitability for sustainable construction in a PA and its surroundings. The methodological approach of Multi-Criteria Decision Analysis was used in the formation of this model and adapted for the research; it was combined with the adapted Analytical hierarchy process and the Delphi process, and supported by a geographical information system (GIS) within the framework of ESRI ArcGIS software - Spatial analyst...
November 2, 2017: Journal of Environmental Management
Alessandro Gonçalves Campolina, Patrícia Coelho De Soárez, Fábio Vieira do Amaral, Jair Minoro Abe
Multi-criteria decision analysis (MCDA) is an emerging tool that allows the integration of relevant factors for health technology assessment (HTA). This study aims to present a summary of the methodological characteristics of MCDA: definitions, approaches, applications, and implementation stages. A case study was conducted in the São Paulo State Cancer Institute (ICESP) in order to understand the perspectives of decision-makers in the process of drafting a recommendation for the incorporation of technology in the Brazilian Unified National Health System (SUS), through a report by the Brazilian National Commission for the Incorporation of Technologies in the SUS (CONITEC)...
October 26, 2017: Cadernos de Saúde Pública
Stephen P Fitzgerald, Nigel G Bean, Ravi P Ruberu
BACKGROUND: The external validity, or generalizability, of trials and guidelines has been considered poor in the context of multiple morbidity. How multiple morbidity might affect the magnitude of benefit of a given treatment, and thereby external validity, has had little study. OBJECTIVE: To provide a method of decision analysis to quantify the effects of age and comorbidity on the probability of deriving a given magnitude of treatment benefit. DESIGN: We developed a method to calculate probabilistically the effect of all of a patient's comorbidities on their underlying utility, or well-being, at a future time point...
2017: J Comorb
Kenneth C Fletcher, Ali E Abbas
This article presents a public value measure that can be used to aid executives in the public sector to better assess policy decisions and maximize value to the American people. Using Transportation Security Administration (TSA) programs as an example, we first identify the basic components of public value. We then propose a public value account to quantify the outcomes of various risk scenarios, and we determine the certain equivalent of several important TSA programs. We illustrate how this proposed measure can quantify the effects of two main challenges that government organizations face when conducting enterprise risk management: (1) short-term versus long-term incentives and (2) avoiding potential negative consequences even if they occur with low probability...
October 30, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
Julia I Drake, Juan Carlos Trujillo de Hart, Clara Monleón, Walter Toro, Joice Valentim
Background and objectives:   MCDA is a decision-making tool with increasing use in the healthcare sector, including HTA (Health Technology Assessment). By applying multiple criteria, including innovation, in a comprehensive, structured and explicit manner, MCDA fosters a transparent, participative, consistent decision-making process taking into consideration values of all stakeholders. This paper by FIFARMA (Latin American Federation of Pharmaceutical Industry) proposes the deliberative (partial) MCDA as a more pragmatic, agile approach, especially when newly implemented...
2017: Journal of Market Access & Health Policy
Jingzheng Ren
This objective of this study is to develop a generic multi-attribute decision analysis framework for ranking the technologies for ballast water treatment and determine their grades. An evaluation criteria system consisting of eight criteria in four categories was used to evaluate the technologies for ballast water treatment. The Best-Worst method, which is a subjective weighting method and Criteria importance through inter-criteria correlation method, which is an objective weighting method, were combined to determine the weights of the evaluation criteria...
October 9, 2017: Chemosphere
Douwe Postmus, Sarah Richard, Nathalie Bere, Gert van Valkenhoef, Jayne Galinsky, Eric Low, Isabelle Moulon, Maria Mavris, Tomas Salmonsson, Beatriz Flores, Hans Hillege, Francesco Pignatti
BACKGROUND: The objectives of this study were to elicit the preferences of patients with multiple myeloma regarding the possible benefits and risks of cancer treatments and to illustrate how such data may be used to estimate patients' acceptance of new treatments. PATIENTS AND METHODS: Patients with multiple myeloma from the cancer charity Myeloma UK were invited to participate in an online survey based on multicriteria decision analysis and swing weighting to elicit individual stated preferences for the following attributes: (a) 1-year progression-free survival (PFS, ranging from 50% to 90%), (b) mild or moderate toxicity for 2 months or longer (ranging from 85% to 45%), and (c) severe or life-threatening toxicity (ranging from 80% to 20%)...
October 27, 2017: Oncologist
Jacqueline N Chu, Jin Choi, Angela Tramontano, Christopher Morse, David Forcione, Norman S Nishioka, Julian A Abrams, Joel H Rubenstein, Chung Yin Kong, John M Inadomi, Chin Hur
BACKGROUND & AIMS: Although treatment of T1a esophageal adenocarcinoma (EAC) is shifting from esophagectomy to endoscopic therapy, T1b EACs are considered too high risk to be treated endoscopically. We investigated the effectiveness and cost effectiveness of esophagectomy vs endoscopic therapy for T1a and T1b EACs, and the effects of age and comorbidities, using a decision analytic Markov model. METHODS: We developed a model to simulate a hypothetical cohort of men 75 years old with Charlson comorbidity index scores of 0 and either T1aN0M0 or T1bN0M0 EAC, as a base case...
October 24, 2017: Clinical Gastroenterology and Hepatology
Diana Brixner, Nikos Maniadakis, Zoltán Kaló, Shanlian Hu, Jie Shen, Kalman Wijaya
Off-patent pharmaceuticals (OPPs) represent more than 60% of the pharmaceutical market in many emerging countries, where they are frequently evaluated primarily on cost rather than with health technology assessment. OPPs are assumed to be identical to the originators. Branded and unbranded generic versions can, however, vary from the originator in active pharmaceutical ingredients, dosage, consistency formulation, excipients, manufacturing processes, and distribution, for example. These variables can alter the efficacy and safety of the product, negatively impacting both the anticipated cost savings and the population's health...
September 2017: Value in Health Regional Issues
Aris Angelis, Gilberto Montibeller, Daniel Hochhauser, Panos Kanavos
BACKGROUND: Multiple criteria decision analysis (MCDA) has appeared as a methodology to address limitations of economic evaluation in health technology assessment (HTA), however there are limited empirical evidence from real world applications. The aim of this study is to test in practice a recently developed MCDA methodological framework known as Advance Value Framework (AVF) through a proof-of-concept case study engaging multiple stakeholders. METHODS: A multi-attribute value theory methodological process was adopted involving problem structuring, model building, model assessment and model appraisal phases...
October 26, 2017: BMC Medical Informatics and Decision Making
Christopher Fitzpatrick, Kingsley Asiedu, Anita Sands, Tita Gonzalez Pena, Michael Marks, Oriol Mitja, Filip Meheus, Patrick Van der Stuyft
BACKGROUND: Yaws is a non-venereal treponemal infection caused by Treponema pallidum subspecies pertenue. The disease is targeted by WHO for eradication by 2020. Rapid diagnostic tests (RDTs) are envisaged for confirmation of clinical cases during treatment campaigns and for certification of the interruption of transmission. Yaws testing requires both treponemal (trep) and non-treponemal (non-trep) assays for diagnosis of current infection. We evaluate a sequential testing strategy (using a treponemal RDT before a trep/non-trep RDT) in terms of cost and cost-effectiveness, relative to a single-assay combined testing strategy (using the trep/non-trep RDT alone), for two use cases: individual diagnosis and community surveillance...
October 2017: PLoS Neglected Tropical Diseases
A John Woodill, Stuart T Nakamoto, Andrea M Kawabata, PingSun Leung
Integrated pest management strategies were adopted to combat the coffee berry borer (CBB) after its arrival in Hawaii in 2010. A decision tree framework is used to model the CBB integrated pest management recommendations, for potential use by growers and to assist in developing and evaluating management strategies and policies. The model focuses on pesticide spraying (spray/no spray) as the most significant pest management decision within each period over the entire crop season. The main result from the analysis suggests the most important parameter to maximize net benefit is to ensure a low initial infestation level...
October 21, 2017: Insects
Ioannis Kougkoulos, Simon J Cook, Vincent Jomelli, Leon Clarke, Elias Symeonakis, Jason M Dortch, Laura A Edwards, Myriam Merad
Glacial Lake Outburst Floods (GLOFs) represent a significant threat in deglaciating environments, necessitating the development of GLOF hazard and risk assessment procedures. Here, we outline a Multi-Criteria Decision Analysis (MCDA) approach that can be used to rapidly identify potentially dangerous lakes in regions without existing tailored GLOF risk assessments, where a range of glacial lake types exist, and where field data are sparse or non-existent. Our MCDA model (1) is desk-based and uses freely and widely available data inputs and software, and (2) allows the relative risk posed by a range of glacial lake types to be assessed simultaneously within any region...
October 19, 2017: Science of the Total Environment
Adrian L Huang, Kednapa Thavorn, Sasha van Katwyk, Peter MacDonald, Peter Lapner
BACKGROUND: The optimal technique for arthroscopic rotator cuff repair is controversial, and both single and double-row techniques are commonly used. In the current era of increasing costs, health-care delivery models are focusing on the value of care. In this study, we compared the cost-effectiveness of single-row and double-row reconstructions in patients undergoing arthroscopic rotator cuff repair. METHODS: A cost-utility analysis was performed from the perspective of a publicly funded health-care system...
October 18, 2017: Journal of Bone and Joint Surgery. American Volume
Chethan M Puttarajappa, Sundaram Hariharan, Kenneth J Smith
BACKGROUND AND OBJECTIVES: Management strategies are unclear for late-onset cytomegalovirus infection occurring beyond 6 months of antiviral prophylaxis in cytomegalovirus high-risk (cytomegalovirus IgG positive to cytomegalovirus IgG negative) kidney transplant recipients. Hybrid strategies (prophylaxis followed by screening) have been investigated but with inconclusive results. There are clinical and potential cost benefits of preventing cytomegalovirus-related hospitalizations and associated increased risks of patient and graft failure...
October 12, 2017: Clinical Journal of the American Society of Nephrology: CJASN
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