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"Decision analysis"

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https://www.readbyqxmd.com/read/28634019/economic-evaluation-of-epinephrine-auto-injectors-for-peanut-allergy
#1
Marcus Shaker, Katherine Bean, Marylee Verdi
BACKGROUND: Three commercial epinephrine auto-injectors were available in the United States in the summer of 2016: EpiPen, Adrenaclick, and epinephrine injection, USP auto-injector. OBJECTIVE: To describe the variation in pharmacy costs among epinephrine auto-injector devices in New England and evaluate the additional expense associated with incremental auto-injector costs. METHODS: Decision analysis software was used to evaluate costs of the most and least expensive epinephrine auto-injector devices for children with peanut allergy...
June 17, 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28631117/multi-criteria-decision-analysis-to-model-ixodes-ricinus-habitat-suitability
#2
Raphaël Rousseau, Guy McGrath, Barry J McMahon, Sophie O Vanwambeke
Tick-borne diseases present a major threat to both human and livestock health throughout Europe. The risk of infection is directly related to the presence of its vector. Thereby it is important to know their distribution, which is strongly associated with environmental factors: the presence and availability of a suitable habitat, of a suitable climate and of hosts. The present study models the habitat suitability for Ixodes ricinus in Ireland, where data on tick distribution are scarce. Tick habitat suitability was estimated at a coarse scale (10 km) with a multi-criteria decision analysis (MCDA) method according to four different scenarios (depending on the variables used and on the weights granted to each of them)...
June 19, 2017: EcoHealth
https://www.readbyqxmd.com/read/28626878/should-women-be-advised-to-use-calcium-supplements-during-pregnancy-a-decision-analysis
#3
Linda J E Meertens, Hubertina C J Scheepers, Jessica P M M Willemse, Marc E A Spaanderman, Luc J M Smits
Adequate calcium intake during pregnancy is important in the prevention of pre-eclampsia. A substantial proportion of pregnant women do not meet the recommended daily calcium intake, even in developed countries. Nonetheless, calcium supplementation is not routinely advised to pregnant women in most countries. We aimed to predict the impact of advising pregnant women to use calcium supplements (1,000 mg/day) on the number of cases of pre-eclampsia prevented and related health care costs. By use of a decision-analytic model, we assessed the expected impact of advising calcium supplementation to either (1) all pregnant women, (2) women at high risk of developing pre-eclampsia, or (3) women with a low dietary calcium intake compared with current care...
June 18, 2017: Maternal & Child Nutrition
https://www.readbyqxmd.com/read/28620949/nonintravenous-rescue-medications-for-pediatric-status-epilepticus-a-cost-effectiveness-analysis
#4
Iván Sánchez Fernández, Marina Gaínza-Lein, Tobias Loddenkemper
OBJECTIVE: To quantify the cost-effectiveness of rescue medications for pediatric status epilepticus: rectal diazepam, nasal midazolam, buccal midazolam, intramuscular midazolam, and nasal lorazepam. METHODS: Decision analysis model populated with effectiveness data from the literature and cost data from publicly available market prices. The primary outcome was cost per seizure stopped ($/SS). One-way sensitivity analyses and second-order Monte Carlo simulations evaluated the robustness of the results across wide variations of the input parameters...
June 16, 2017: Epilepsia
https://www.readbyqxmd.com/read/28619689/risks-and-benefits-of-opportunistic-salpingectomy-during-vaginal-hysterectomy-a-decision-analysis
#5
Lauren A Cadish, Jonathan P Shepherd, Emma L Barber, Beri Ridgeway
BACKGROUND: Fallopian tubes are commonly removed during laparoscopic and open hysterectomy to prevent ovarian and tubal cancer, but are not routinely removed during vaginal hysterectomy due to perceptions of increased morbidity, difficulty, or inadequate surgical training. OBJECTIVE: We sought to quantify complications and costs associated with a strategy of planned salpingectomy during vaginal hysterectomy. STUDY DESIGN: We created a decision analysis model using TreeAgePro...
June 12, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28606435/cost-minimization-analysis-of-ganglion-cyst-excision
#6
Eric Quan Pang, Steven Zhang, Alex H S Harris, Robin N Kamal
PURPOSE: Cost minimization analysis can be employed to determine the least costly option when multiple treatments lead to equivalent outcomes. We present a cost minimization analysis from the payers' perspective, of the direct per patient cost of arthroscopic versus open ganglion cyst excision. We tested the null hypothesis that there is no difference in cost between the 2 procedures from the payer perspective. METHODS: We utilized data from a private payer administrative claims database comprising 16 million individuals from 2007 to 2015...
June 9, 2017: Journal of Hand Surgery
https://www.readbyqxmd.com/read/28576711/safety-and-efficacy-of-antibacterial-prophylaxis-after-craniotomy-a-decision-model-analysis
#7
Amal F Alotaibi, Rania A Mekary, Hasan A Zaidi, Timothy R Smith, Ankur Pandya
BACKGROUND: Antibiotic prophylaxis has revolutionized the safety of neurosurgical procedures in the last century. Today, the clinician's drug of choice prior surgery is often based on the antibiotic's resistance profile and drug-induced complications. METHODS: A decision tree model was developed to compare cefazolin (cephalosporin), vancomycin, or their combination on 90-day mortality post-craniotomy. We modeled the infection type (methicillin-sensitive, methicillin-resistant, or other organisms), antibiotic-related complications that could affect mortality (e...
May 30, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28570572/optimal-costs-of-hiv-pre-exposure-prophylaxis-for-men-who-have-sex-with-men
#8
Jennie McKenney, Anders Chen, Karen W Hoover, Jane Kelly, David Dowdy, Parastu Sharifi, Patrick S Sullivan, Eli S Rosenberg
INTRODUCTION: Men who have sex with men (MSM) are disproportionately affected by HIV due to their increased risk of infection. Oral pre-exposure prophylaxis (PrEP) is a highly effictive HIV-prevention strategy for MSM. Despite evidence of its effectiveness, PrEP uptake in the United States has been slow, in part due to its cost. As jurisdictions and health organizations begin to think about PrEP scale-up, the high cost to society needs to be understood. METHODS: We modified a previously-described decision-analysis model to estimate the cost per quality-adjusted life-year (QALY) gained, over a 1-year duration of PrEP intervention and lifetime time horizon...
2017: PloS One
https://www.readbyqxmd.com/read/28561259/cost-effectiveness-of-high-sensitivity-faecal-immunochemical-test-and-colonoscopy-screening-for-colorectal-cancer
#9
M Aronsson, P Carlsson, L-Å Levin, J Hager, R Hultcrantz
BACKGROUND: Colorectal cancer screening can decrease morbidity and mortality. However, there are widespread differences in the implementation of programmes and choice of strategy. The primary objective of this study was to estimate lifelong costs and health outcomes of two of the currently most preferred methods of screening for colorectal cancer: colonoscopy and sensitive faecal immunochemical test (FIT). METHODS: A cost-effectiveness analysis of colorectal cancer screening in a Swedish population was performed using a decision analysis model, based on the design of the Screening of Swedish Colons (SCREESCO) study, and data from the published literature and registries...
May 31, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/28560532/can-a-multivariate-model-for-survival-estimation-in-skeletal-metastases-pathfx-be-externally-validated-using-japanese-patients
#10
Koichi Ogura, Tabu Gokita, Yusuke Shinoda, Hirotaka Kawano, Tatsuya Takagi, Keisuke Ae, Akira Kawai, Rikard Wedin, Jonathan A Forsberg
BACKGROUND: Objective survival estimates are important when treating or studying outcomes in patients with skeletal metastases. One decision-support tool, PATHFx (www.pathfx.org) is designed to predict each patient's postsurgical survival trajectory at 1, 3, 6, and 12 months in patients undergoing stabilization for skeletal metastases. PATHFx has been externally validated in various western centers, but it is unknown whether it may be useful in Asian patient populations. QUESTIONS/PURPOSES: We asked (1) whether the PATHFx models are as predictive in Japanese patients by estimating the area under the receiver operator characteristic curve (AUC); we considered an AUC greater than 0...
May 30, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28552973/identification-of-foot-and-mouth-disease-risk-areas-using-a-multi-criteria-analysis-approach
#11
Diego Viali Dos Santos, Gustavo Sousa E Silva, Eliseu José Weber, Heinrich Hasenack, Fernando Henrique Sautter Groff, Bernardo Todeschini, Mauro Riegert Borba, Antonio Augusto Rosa Medeiros, Vanessa Bielefeldt Leotti, Cláudio Wageck Canal, Luis Gustavo Corbellini
Foot and mouth disease (FMD) is a highly infectious disease that affects cloven-hoofed livestock and wildlife. FMD has been a problem for decades, which has led to various measures to control, eradicate and prevent FMD by National Veterinary Services worldwide. Currently, the identification of areas that are at risk of FMD virus incursion and spread is a priority for FMD target surveillance after FMD is eradicated from a given country or region. In our study, a knowledge-driven spatial model was built to identify risk areas for FMD occurrence and to evaluate FMD surveillance performance in Rio Grande do Sul state, Brazil...
2017: PloS One
https://www.readbyqxmd.com/read/28551536/decision-making-in-irrigation-networks-selecting-appropriate-canal-structures-using-multi-attribute-decision-analysis
#12
Zeinab Hosseinzade, Sheree A Pagsuyoin, Kumaraswamy Ponnambalam, Mohammad J Monem
The stiff competition for water between agriculture and non-agricultural production sectors makes it necessary to have effective management of irrigation networks in farms. However, the process of selecting flow control structures in irrigation networks is highly complex and involves different levels of decision makers. In this paper, we apply multi-attribute decision making (MADM) methodology to develop a decision analysis (DA) framework for evaluating, ranking and selecting check and intake structures for irrigation canals...
May 25, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28546894/needs-and-challenges-for-assessing-the-environmental-impacts-of-engineered-nanomaterials-enms
#13
REVIEW
Michelle Romero-Franco, Hilary A Godwin, Muhammad Bilal, Yoram Cohen
The potential environmental impact of nanomaterials is a critical concern and the ability to assess these potential impacts is top priority for the progress of sustainable nanotechnology. Risk assessment tools are needed to enable decision makers to rapidly assess the potential risks that may be imposed by engineered nanomaterials (ENMs), particularly when confronted by the reality of limited hazard or exposure data. In this review, we examine a range of available risk assessment frameworks considering the contexts in which different stakeholders may need to assess the potential environmental impacts of ENMs...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/28538287/cost-utility-analysis-of-reconstruction-compared-with-primary-amputation-for-patients-with-severe-lower-limb-trauma-in-colombia
#14
Mateo Ceballos, Carlos Oliver Valderrama, Luis Esteban Orozco, Laura Sánchez, Juan Pablo Valderrama, Luz Helena Lugo
BACKGROUND: To establish, from the health system perspective, the cost-utility relationship of limb reconstruction compared with primary amputation for patients over 32 years with grade IIIB and IIIC severe lower limb trauma in Colombia, S.A. METHODS: A Markov model was built including different short-term and long-term states that represent the main events that a patient could experience after a lower limb amputation or a reconstruction. A 42-year time horizon was considered for the base case...
May 17, 2017: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/28535105/the-importance-of-economic-perspective-and-quantitative-approaches-in-oncology-value-frameworks-of-drug-selection-and-shared-decision-making
#15
A Reginald Waldeck, Marc F Botteman, Richard E White, Ben A van Hout
The debate around value in oncology drug selection has been prominent in recent years, and several professional bodies have furthered this debate by advocating for so-called value frameworks. Herein, we provide a viewpoint on these value frameworks, emphasizing the need to consider 4 key aspects: (1) the economic underpinnings of value; (2) the importance of the perspective adopted in the valuation; (3) the importance of the difference between absolute and relative measures of risk and measuring patient preferences; and (4) the recognition of multiple quality-of-life (QoL) domains, and the aggregation and valuation of those domains, through utilities within a multicriteria decision analysis, may allow prioritization of QoL above the tallying of safety events, particularly in a value framework focusing on the individual patient...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28514962/revisiting-annual-screening-for-latent-tuberculosis-infection-in-healthcare-workers-a-cost-effectiveness-analysis
#16
Guillaume A Mullie, Kevin Schwartzman, Alice Zwerling, Dieynaba S N'Diaye
BACKGROUND: In North America, tuberculosis incidence is now very low and risk to healthcare workers has fallen. Indeed, recent cohort data question routine annual tuberculosis screening in this context. We compared the cost-effectiveness of three potential strategies for ongoing screening of North American healthcare workers at risk of exposure. The analysis did not evaluate the cost-effectiveness of screening at hiring, and considered only workers with negative baseline tests. METHODS: A decision analysis model simulated a hypothetical cohort of 1000 workers following negative baseline tests, considering duties, tuberculosis exposure, testing and treatment...
May 17, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28514203/cost-effectiveness-of-mr-imaging-guided-strategies-for-detection-of-prostate-cancer-in-biopsy-naive-men
#17
Shivani Pahwa, Nicholas K Schiltz, Lee E Ponsky, Ziang Lu, Mark A Griswold, Vikas Gulani
Purpose To evaluate the cost-effectiveness of multiparametric diagnostic magnetic resonance (MR) imaging examination followed by MR imaging-guided biopsy strategies in the detection of prostate cancer in biopsy-naive men presenting with clinical suspicion of cancer for the first time. Materials and Methods A decision-analysis model was created for biopsy-naive men who had been recommended for prostate biopsy on the basis of abnormal digital rectal examination results or elevated prostate-specific antigen levels (age groups: 41-50 years, 51-60 years, and 61-70 years)...
May 17, 2017: Radiology
https://www.readbyqxmd.com/read/28499120/characterising-bias-in-regulatory-risk-and-decision-analysis-an-analysis-of-heuristics-applied-in-health-technology-appraisal-chemicals-regulation-and-climate-change-governance
#18
Brian H MacGillivray
In many environmental and public health domains, heuristic methods of risk and decision analysis must be relied upon, either because problem structures are ambiguous, reliable data is lacking, or decisions are urgent. This introduces an additional source of uncertainty beyond model and measurement error - uncertainty stemming from relying on inexact inference rules. Here we identify and analyse heuristics used to prioritise risk objects, to discriminate between signal and noise, to weight evidence, to construct models, to extrapolate beyond datasets, and to make policy...
May 9, 2017: Environment International
https://www.readbyqxmd.com/read/28488253/increase-in-total-joint-arthroplasty-projected-from-2014-to-2046-in-australia-a-conservative-local-model-with-international-implications
#19
Maria C S Inacio, Stephen E Graves, Nicole L Pratt, Elizabeth E Roughead, Szilard Nemes
BACKGROUND: The incidence of joint arthroplasty is increasing worldwide. International estimates of future demand for joint arthroplasty have used models that propose either an exponential future increase, despite obvious system constraints, or static increases, which do not account for past trends. Country-specific projection estimates that address limitations of past projections are necessary. In Australia, a high-income country with the 7th highest incidence of TKA and 15th highest incidence of THA of the Organization for Economic Cooperation and Development (OECD) countries, the volume of TKAs and THAs increased 198% between 1994 and 2014...
May 9, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28485006/the-impact-of-appointment-based-medication-synchronization-on-medication-taking-behaviour-and-health-outcomes-a-systematic-review
#20
REVIEW
E Nguyen, D M Sobieraj
WHAT IS KNOWN AND OBJECTIVE: Proactive synchronization of medication refills through an appointment-based model (ABM) is a community pharmacy-based intervention targeting adherence to medications. We aimed to systematically review evidence on the impact of the ABM on medication taking behaviour, health resource utilization, clinical outcomes and the preferences of patients and providers. METHODS: We conducted a systematic literature search of MEDLINE and Scopus from database inception through 6 February 2017...
May 8, 2017: Journal of Clinical Pharmacy and Therapeutics
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