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"Decision analysis"

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https://www.readbyqxmd.com/read/28535105/the-importance-of-economic-perspective-and-quantitative-approaches-in-oncology-value-frameworks-of-drug-selection-and-shared-decision-making
#1
A Reginald Waldeck, Marc F Botteman, Richard E White, Ben A van Hout
The debate around value in oncology drug selection has been prominent in recent years, and several professional bodies have furthered this debate by advocating for so-called value frameworks. Herein, we provide a viewpoint on these value frameworks, emphasizing the need to consider 4 key aspects: (1) the economic underpinnings of value; (2) the importance of the perspective adopted in the valuation; (3) the importance of the difference between absolute and relative measures of risk and measuring patient preferences; and (4) the recognition of multiple quality-of-life (QoL) domains, and the aggregation and valuation of those domains, through utilities within a multicriteria decision analysis, may allow prioritization of QoL above the tallying of safety events, particularly in a value framework focusing on the individual patient...
June 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28514962/revisiting-annual-screening-for-latent-tuberculosis-infection-in-healthcare-workers-a-cost-effectiveness-analysis
#2
Guillaume A Mullie, Kevin Schwartzman, Alice Zwerling, Dieynaba S N'Diaye
BACKGROUND: In North America, tuberculosis incidence is now very low and risk to healthcare workers has fallen. Indeed, recent cohort data question routine annual tuberculosis screening in this context. We compared the cost-effectiveness of three potential strategies for ongoing screening of North American healthcare workers at risk of exposure. The analysis did not evaluate the cost-effectiveness of screening at hiring, and considered only workers with negative baseline tests. METHODS: A decision analysis model simulated a hypothetical cohort of 1000 workers following negative baseline tests, considering duties, tuberculosis exposure, testing and treatment...
May 17, 2017: BMC Medicine
https://www.readbyqxmd.com/read/28514203/cost-effectiveness-of-mr-imaging-guided-strategies-for-detection-of-prostate-cancer-in-biopsy-naive-men
#3
Shivani Pahwa, Nicholas K Schiltz, Lee E Ponsky, Ziang Lu, Mark A Griswold, Vikas Gulani
Purpose To evaluate the cost-effectiveness of multiparametric diagnostic magnetic resonance (MR) imaging examination followed by MR imaging-guided biopsy strategies in the detection of prostate cancer in biopsy-naive men presenting with clinical suspicion of cancer for the first time. Materials and Methods A decision-analysis model was created for biopsy-naive men who had been recommended for prostate biopsy on the basis of abnormal digital rectal examination results or elevated prostate-specific antigen levels (age groups: 41-50 years, 51-60 years, and 61-70 years)...
May 17, 2017: Radiology
https://www.readbyqxmd.com/read/28499120/characterising-bias-in-regulatory-risk-and-decision-analysis-an-analysis-of-heuristics-applied-in-health-technology-appraisal-chemicals-regulation-and-climate-change-governance
#4
Brian H MacGillivray
In many environmental and public health domains, heuristic methods of risk and decision analysis must be relied upon, either because problem structures are ambiguous, reliable data is lacking, or decisions are urgent. This introduces an additional source of uncertainty beyond model and measurement error - uncertainty stemming from relying on inexact inference rules. Here we identify and analyse heuristics used to prioritise risk objects, to discriminate between signal and noise, to weight evidence, to construct models, to extrapolate beyond datasets, and to make policy...
May 9, 2017: Environment International
https://www.readbyqxmd.com/read/28488253/increase-in-total-joint-arthroplasty-projected-from-2014-to-2046-in-australia-a-conservative-local-model-with-international-implications
#5
Maria C S Inacio, Stephen E Graves, Nicole L Pratt, Elizabeth E Roughead, Szilard Nemes
BACKGROUND: The incidence of joint arthroplasty is increasing worldwide. International estimates of future demand for joint arthroplasty have used models that propose either an exponential future increase, despite obvious system constraints, or static increases, which do not account for past trends. Country-specific projection estimates that address limitations of past projections are necessary. In Australia, a high-income country with the 7th highest incidence of TKA and 15th highest incidence of THA of the Organization for Economic Cooperation and Development (OECD) countries, the volume of TKAs and THAs increased 198% between 1994 and 2014...
May 9, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28485006/the-impact-of-appointment-based-medication-synchronization-on-medication-taking-behaviour-and-health-outcomes-a-systematic-review
#6
REVIEW
E Nguyen, D M Sobieraj
WHAT IS KNOWN AND OBJECTIVE: Proactive synchronization of medication refills through an appointment-based model (ABM) is a community pharmacy-based intervention targeting adherence to medications. We aimed to systematically review evidence on the impact of the ABM on medication taking behaviour, health resource utilization, clinical outcomes and the preferences of patients and providers. METHODS: We conducted a systematic literature search of MEDLINE and Scopus from database inception through 6 February 2017...
May 8, 2017: Journal of Clinical Pharmacy and Therapeutics
https://www.readbyqxmd.com/read/28481881/comparing-multi-criteria-decision-analysis-and-integrated-assessment-to-support-long-term-water-supply-planning
#7
Lisa Scholten, Max Maurer, Judit Lienert
We compare the use of multi-criteria decision analysis (MCDA)-or more precisely, models used in multi-attribute value theory (MAVT)-to integrated assessment (IA) models for supporting long-term water supply planning in a small town case study in Switzerland. They are used to evaluate thirteen system scale water supply alternatives in four future scenarios regarding forty-four objectives, covering technical, social, environmental, and economic aspects. The alternatives encompass both conventional and unconventional solutions and differ regarding technical, spatial and organizational characteristics...
2017: PloS One
https://www.readbyqxmd.com/read/28476140/anemia-risk-in-relation-to-lead-exposure-in-lead-related-manufacturing
#8
Nan-Hung Hsieh, Shun-Hui Chung, Szu-Chieh Chen, Wei-Yu Chen, Yi-Hsien Cheng, Yi-Jun Lin, Su-Han You, Chung-Min Liao
BACKGROUND: Lead-exposed workers may suffer adverse health effects under the currently regulated blood lead (BPb) levels. However, a probabilistic assessment about lead exposure-associated anemia risk is lacking. The goal of this study was to examine the association between lead exposure and anemia risk among factory workers in Taiwan. METHODS: We first collated BPb and indicators of hematopoietic function data via health examination records that included 533 male and 218 female lead-exposed workers between 2012 and 2014...
May 5, 2017: BMC Public Health
https://www.readbyqxmd.com/read/28470542/a-comparative-analysis-of-a-disposable-and-a-reusable-pedicle-screw-instrument-kit-for-lumbar-arthrodesis-integrating-hta-and-mcda
#9
Claudia Ottardi, Alessio Damonti, Emanuele Porazzi, Emanuela Foglia, Lucrezia Ferrario, Tomaso Villa, Enrico Aimar, Marco Brayda-Bruno, Fabio Galbusera
OBJECTIVE: Lumbar arthrodesis is a common surgical technique that consists of the fixation of one or more motion segments with pedicle screws and rods. However, spinal surgery using these techniques is expensive and has a significant impact on the budgets of hospitals and Healthcare Systems. While reusable and disposable instruments for laparoscopic interventions have been studied in literature, no specific information exists regarding instrument kits for lumbar arthrodesis. The aim of the present study was to perform a complete health technology assessment comparing a disposable instrument kit for lumbar arthrodesis (innovative device) with the standard reusable instrument...
December 2017: Health Economics Review
https://www.readbyqxmd.com/read/28463921/the-cost-effectiveness-of-dual-mobility-implants-for-primary-total-hip-arthroplasty-a-computer-based-cost-utility-model
#10
Brian T Barlow, Alexander S McLawhorn, Geoffrey H Westrich
BACKGROUND: Dislocation remains a clinically important problem following primary total hip arthroplasty, and it is a common reason for revision total hip arthroplasty. Dual mobility (DM) implants decrease the risk of dislocation but can be more expensive than conventional implants and have idiosyncratic failure mechanisms. The purpose of this study was to investigate the cost-effectiveness of DM implants compared with conventional bearings for primary total hip arthroplasty. METHODS: Markov model analysis was conducted from the societal perspective with use of direct and indirect costs...
May 3, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28463547/economic-decision-model-for-first-time-traumatic-patellar-dislocations-in-adolescents
#11
Benedict U Nwachukwu, Conan So, William W Schairer, Beth E Shubin-Stein, Sabrina M Strickland, Daniel W Green, Emily R Dodwell
BACKGROUND: The surgical management of traumatic patellar dislocations in adolescents is associated with a lower rate of recurrent dislocations compared with nonoperative care. However, the attendant cost of surgery and the quality-of-life benefit of a surgical treatment strategy are unclear. PURPOSE: To compare the cost-utility of 3 management strategies for acute first-time patellar dislocations in adolescents: (1) nonoperative treatment only, (2) initial nonoperative treatment with surgery only for recurrent dislocations, and (3) immediate surgery...
May 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28459710/cost-minimization-analysis-of-the-management-of-acute-achilles-tendon-rupture
#12
Jeremy N Truntzer, Brian Triana, Alex H S Harris, Laurence Baker, Loretta Chou, Robin N Kamal
BACKGROUND: Outcomes of nonsurgical management of acute Achilles tendon rupture have been demonstrated to be noninferior to those of surgical management. We performed a cost-minimization analysis of surgical and nonsurgical management of acute Achilles tendon rupture. METHODS: We used a claims database to identify patients who underwent surgical (n = 1,979) and nonsurgical (n = 3,065) management of acute Achilles tendon rupture and compared overall costs of treatment (surgical procedure, follow-up care, physical therapy, and management of complications)...
June 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28454778/decision-analysis-to-identify-the-ideal-treatment-for-adult-spinal-deformity-what-is-the-impact-of-complications-on-treatment-outcomes
#13
Emre Acaroglu, Umit Ozgur Guler, Aysun Cetinyurek-Yavuz, Selcen Yuksel, Yasemin Yavuz, Selim Ayhan, Montse Domingo-Sabat, Ferran Pellise, Ahmet Alanay, Francesco S Perez Grueso, Frank Kleinstück, Ibrahim Obeid
OBJECTIVE: The aim of this study was to analyze the impact of treatment complications on outcomes in adult spinal deformity (ASD) using a decision analysis (DA) model. METHODS: The study included 535 ASD patients (371 with non-surgical (NS) and 164 with surgical (S) treatment) from an international multicentre database of ASD patients. DA was structured in two main steps; 1) Baseline analysis (Assessing the probabilities of outcomes, Assessing the values of preference -utilities-, Combining information on probability and utility and assigning the quality adjusted life expectancy (QALE) for each treatment) and 2) Sensitivity analysis...
April 25, 2017: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28451601/cost-comparison-of-outpatient-versus-inpatient-unicompartmental-knee-arthroplasty
#14
Dustin L Richter, David R Diduch
BACKGROUND: Outpatient unicompartmental knee arthroplasty (UKA) has been shown to be safe and feasible when compared with inpatient surgery; however, no studies have evaluated the cost-effectiveness and cost-benefit of performing outpatient versus inpatient UKA. HYPOTHESIS: Significant cost savings can be achieved by transitioning UKAs from an inpatient to an outpatient procedure in an outpatient surgical facility, with no appreciable difference in complication or readmission rates...
March 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28449210/middle-meatal-packing-in-endoscopic-sinus-surgery-to-pack-or-not-to-pack-a-decision-analysis-model
#15
Sagit Stern-Shavit, Yuval Nachalon, Moshe Leshno, Ethan Soudry
BACKGROUND: Packing of the middle meatus and ethmoid cavities is a common practice in endoscopic sinus surgery (ESS), but its necessity recently has been challenged. The aim of this study was to formulate a decision-analysis model to determine the need for packing in ESS and identify variables affecting the decision. METHODS: A systematic review of the literature was conducted for all randomized control trials comparing packing to no packing in ESS, and a decision-analysis model was generated...
April 27, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28434413/drug-evaluation-and-decision-making-in-catalonia-development-and-validation-of-a-methodological-framework-based-on-multi-criteria-decision-analysis-mcda-for-orphan-drugs
#16
Antoni Gilabert-Perramon, Josep Torrent-Farnell, Arancha Catalan, Alba Prat, Manel Fontanet, Ruth Puig-Peiró, Sandra Merino-Montero, Hanane Khoury, Mireille M Goetghebeur, Xavier Badia
OBJECTIVES: The aim of this study was to adapt and assess the value of a Multi-Criteria Decision Analysis (MCDA) framework (EVIDEM) for the evaluation of Orphan drugs in Catalonia (Catalan Health Service). METHODS: The standard evaluation and decision-making procedures of CatSalut were compared with the EVIDEM methodology and contents. The EVIDEM framework was adapted to the Catalan context, focusing on the evaluation of Orphan drugs (PASFTAC program), during a Workshop with sixteen PASFTAC members...
April 24, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28431811/potential-consequences-of-not-using-live-attenuated-influenza-vaccine
#17
Kenneth J Smith, Mary Patricia Nowalk, Angela Wateska, Shawn T Brown, Jay V DePasse, Jonathan M Raviotta, Eunha Shim, Richard K Zimmerman
INTRODUCTION: Decreased live attenuated influenza vaccine (LAIV) effectiveness in the U.S. prompted the Advisory Committee on Immunization Practices in August 2016 to recommend against this vaccine's use. However, overall influenza uptake increases when LAIV is available and, unlike the U.S., LAIV has retained its effectiveness in other countries. These opposing countercurrents create a dilemma. METHODS: To examine the potential consequences of the decision to not recommend LAIV, which may result in decreased influenza vaccination coverage in the U...
April 18, 2017: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28420381/operations-research-in-global-health-a-scoping-review-with-a-focus-on-the-themes-of-health-equity-and-impact
#18
REVIEW
Beverly D Bradley, Tiffany Jung, Ananya Tandon-Verma, Bassem Khoury, Timothy C Y Chan, Yu-Ling Cheng
BACKGROUND: Operations research (OR) is a discipline that uses advanced analytical methods (e.g. simulation, optimisation, decision analysis) to better understand complex systems and aid in decision-making. Herein, we present a scoping review of the use of OR to analyse issues in global health, with an emphasis on health equity and research impact. A systematic search of five databases was designed to identify relevant published literature. A global overview of 1099 studies highlights the geographic distribution of OR and common OR methods used...
April 18, 2017: Health Research Policy and Systems
https://www.readbyqxmd.com/read/28418507/use-of-bayesian-decision-analysis-to-minimize-harm-in-patient-centered-randomized-clinical-trials-in-oncology
#19
Vahid Montazerhodjat, Shomesh E Chaudhuri, Daniel J Sargent, Andrew W Lo
Importance: Randomized clinical trials (RCTs) currently apply the same statistical threshold of alpha = 2.5% for controlling for false-positive results or type 1 error, regardless of the burden of disease or patient preferences. Is there an objective and systematic framework for designing RCTs that incorporates these considerations on a case-by-case basis? Objective: To apply Bayesian decision analysis (BDA) to cancer therapeutics to choose an alpha and sample size that minimize the potential harm to current and future patients under both null and alternative hypotheses...
April 13, 2017: JAMA Oncology
https://www.readbyqxmd.com/read/28418204/modeling-aesthetics-to-support-an-ecosystem-services-approach-for-natural-resource-management-decision-making
#20
Pieter N Booth, Sheryl A Law, Jane Ma, John Buonogurio, James Boyd, Jessica Turnley
This paper reviews literature on aesthetics and describes the development of vista and landscape aesthetics models. Spatially explicit variables were chosen to represent physical characteristics of natural landscapes that are important to aesthetic preferences. A vista aesthetics model evaluates the aesthetics of natural landscapes viewed from distances over 1,000 m. and a landscape aesthetics model evaluates the aesthetic value of wetlands and forests within 1,000 m from the viewer. Each of the model variables is quantified using spatially-explicit metrics on a pixel-specific basis within EcoAIM™, a GIS-based ecosystem services decision analysis support tool...
April 18, 2017: Integrated Environmental Assessment and Management
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