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Gynecology surgery

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https://www.readbyqxmd.com/read/29029113/estrogen-metabolism-in-abdominal-subcutaneous-and-visceral-adipose-tissue-in-postmenopausal-women
#1
Natalia Hetemäki, Hanna Savolainen-Peltonen, Matti J Tikkanen, Feng Wang, Hanna Paatela, Esa Hämäläinen, Ursula Turpeinen, Mikko Haanpää, Veera Vihma, Tomi S Mikkola
CONTEXT: In postmenopausal women, adipose tissue (AT) levels of estrogens exceed circulating concentrations. While increased visceral AT after menopause is related to metabolic diseases, little is known about differences in estrogen metabolism between different AT depots. OBJECTIVE: We compared concentrations of and metabolic pathways producing estrone and estradiol in abdominal subcutaneous and visceral AT in postmenopausal women. DESIGN, SETTING, PATIENTS, AND INTERVENTIONS: AT and serum samples were obtained from 37 postmenopausal women undergoing surgery for non-malignant gynecological reasons...
September 29, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29028293/a-large-case-series-on-surgical-outcomes-in-congenital-fxiii-deficiency-patients-in-iran
#2
Majid Naderi, Sezaneh Haghpanah, Ghasem Miri-Aliabad, Hakimeh Tavosi, Mehran Karimi
BACKGROUND: The lack of accepted standardized surgical guidelines leads to dependence on the treating physicians' and centers' experiences. AIM: Our aim is to evaluate the surgical outcomes on a large group of congenital FXIII deficiency (FXIIID) patients. METHODS: A case series study was conducted on congenital FXIIID patients in two major referral centers located in Iran from 2010 to 2016 prior to surgery. All patients were on prophylaxis using plasma factor XIII concentrate (10 U kg(-1) , every 28 days) except three patients...
October 13, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29027829/mental-health-pain-symptoms-and-systemic-comorbidities-in-women-with-endometriosis-a-cross-sectional-study
#3
Silvia Vannuccini, Lucia Lazzeri, Cinzia Orlandini, Giuseppe Morgante, Giuseppe Bifulco, Andrea Fagiolini, Felice Petraglia
INTRODUCTION: Endometriosis is a gynecological disease with a severe impact on quality of life. The aim of this study is to assess mental health status in a group of women with endometriosis, investigating their clinical history, pain symptoms and systemic comorbidities. METHODS: An observational cross-sectional study was performed on a group of Italian Caucasian women with endometriosis (n = 134). All patients filled the 'Patient Health Questionnaire' (PHQ), a self-administered screening tool for mental health disorders...
October 13, 2017: Journal of Psychosomatic Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29027715/diagnostic-performance-of-human-epididymis-protein-4-compared-to-a-combination-of-biophysical-and-biochemical-markers-to-differentiate-ovarian-endometriosis-from-epithelial-ovarian-cancer-in-premenopausal-women
#4
Tanja Nikolova, Radomir Zivadinovic, Nina Evtimovska, Violeta Klisarovska, Marko Stanojevic, Jadranka Georgievska, Natasha Nikolova
AIM: This study is a comparison of human epididymis protein 4 (HE4) with cancer antigen 125 (CA125), using the Risk of Ovarian Malignancy Algorithm (ROMA), Copenhagen Index (CPH-I), Risk of Malignancy Index (RMI) and Morphology Index (MI) to differentiate ovarian endometriosis from epithelial ovarian cancer (EOC) in premenopausal women. METHODS: The study was performed at the University Clinic of Obstetrics and Gynecology in Skopje. One hundred and sixty-four premenopausal patients were divided into three study groups, including ovarian endometriosis (37), other benign pelvic masses (57) and EOCs (11), and a control group (59)...
October 13, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29027639/robotic-laparoendoscopic-single-site-benign-gynecologic-surgery-a-single-center-experience
#5
J Jayakumaran, K Wiercinski, C Buffington, A Caceres
The da Vinci Xi surgical system was released with several upgrades and modifications compared to the previous robotic generations to facilitate minimal invasive surgery. Herein, we present our preliminary experience of robotic laparoendoscopic single-site gynecologic surgery performed for benign indications with the da Vinci Xi robotic system in a single center. Thirty-five female patients underwent robotic single-site surgery between June 2016 and January 2017. The median console time for hysterectomy with or without salpingo-oophorectomy was 41 min...
October 13, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29026364/recurrent-pneumothoraces-in-a-patient-with-pulmonary-benign-metastasizing-leiomyoma
#6
Miranda Hann, Rinu Manacheril, Jerry St Pierre, Rajiv Gala
BACKGROUND: Pulmonary benign metastasizing leiomyoma (BML) is a rare disease with a malignant characteristic of spread from the uterus. Most cases are asymptomatic, and only 1% are associated with pneumothorax. CASE REPORT: We present the case of a 42-year-old female with recurrent pneumothoraces leading to an incidental finding of diffuse bilateral pulmonary nodules. The diagnosis of BML was based on the patient's history of uterine leiomyomata and confirmed by a biopsy showing benign smooth muscle staining for desmin and vimentin...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29026316/clinical-effects-of-autologous-cytokine-induced-killer-cell-based-immunotherapy-in-the-treatment-of-endometrial-cancer-a-case-report-and-literature-review
#7
Yong Zhang, Yalong Qi, Axiang Wang, Baozhen Ma, Xiaomin Fu, Lingdi Zhao, Quanli Gao
Endometrial cancer is the most prevalent gynecological malignancy in the USA, and its treatment involves surgery, chemotherapy, and radiotherapy. Cytokine-induced killer (CIK) cell-based treatments have shown antitumor activity against several solid tumors. However, to the best of our knowledge, there are no reports yet of CIK immunotherapy in the treatment of endometrial cancer, and consequently, little is known about its efficacy and safety. Here, we report a case of an endometrial cancer patient receiving a combination treatment with CIK cells immunotherapy and chemotherapy...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29026065/urethral-diverticulum-presenting-as-a-large-vaginal-mass-complicating-pregnancy-and-delivery
#8
Everett F Magann, Lisa S Newton, Susan A Barr
BACKGROUND A case report of urethral diverticulum complicating pregnancy is presented. The diagnosis and management are challenging because of the rare nature of this condition, the varied presentations and differential diagnoses, and the possibility of misdiagnosis. CASE REPORT A 25-year-old primigravida with scheduled induction of labor at 39 weeks gestation due to gestational diabetes mellitus presented for a routine antenatal appointment at 38 weeks and four days. On digital cervical examination, she was found to have a large semi-solid anterior vaginal mass, shown by trans-vaginal ultrasound to have a nearly solid appearance of a 5×7 cm mass with septation...
October 13, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/29024798/hysteroscopic-management-of-asherman-s-syndrome-special-issue-report-on-uterine-surgery-in-the-journal-of-minimally-invasive-gynecology
#9
Zaraq Khan, Jeffrey M Goldberg
In developed countries, Asherman's Syndrome is almost always the result of a prior intrauterine operative trauma. This is often asymptomatic but may result in hypo- or amenorrhea and can contribute to infertility and pregnancy complications. We will review their etiology, clinical implications, and the systems which have been proposed to classify their extent. The numerous methods reported for performing lysis of intrauterine adhesions will be summarized along with the clinical results. Current strategies to prevent recurrence of intrauterine adhesions have not been conclusively shown to be clinically effective but the potential for endometrial regeneration using stem cells is an exciting modality under investigation...
October 9, 2017: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/29022054/diagnosis-and-management-of-365-ureteric-injuries-following-obstetric-and-gynecologic-surgery-in-resource-limited-settings
#10
Thomas J I P Raassen, Carrie J Ngongo, Marietta M Mahendeka
INTRODUCTION: Ureteric injuries are among the most serious complications of pelvic surgery. The incidence in low-resource settings is not well documented. METHODS: This retrospective review analyzes a cohort of 365 ureteric injuries with ureterovaginal fistulas in 353 women following obstetric and gynecologic operations in 11 countries in Africa and Asia, all low-resource settings. The patients with ureteric injury were stratified into three groups according to the initial surgery: (a) obstetric operations, (b) gynecologic operations, and (c) vesicovaginal fistula (VVF) repairs...
October 11, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29019899/effect-of-cerebral-oxygen-saturation-on-postoperative-nausea-and-vomiting-in-female-laparoscopic-surgery-patients
#11
WenJun Guo, Jie Ding, XiaoJu Jin, GaoJie Li
BACKGROUND: The purpose of this study was to investigate effect of cerebral oxygen saturation (SCTO2) on postoperative nausea and vomiting (PONV) in female patients who underwent laparoscopic surgery. METHODS: This study included 90 female patients who underwent laparoscopic surgery (60 cases of gynecological operations and 30 cases of gallbladder operations). All patients were allocated into 3 groups of 30 patients each: group A (gynecological laparoscopic surgery), group B (gynecological laparoscopic surgery with mannitol treatment) and group C (laparoscopic cholecystectomy surgery)...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29018838/adverse-post-operative-outcomes-in-jehovah-s-witnesses-with-gynecologic-cancer-within-30%C3%A2-days-of-surgery-a-single-institution-review-of-36-cases
#12
Laura J Moulton, Peter G Rose, Haider Mahdi
Rates of blood transfusion are reported as high as 32% in women undergoing major gynecologic cancer surgery. Therefore, care of the gynecologic oncology patient who refuses blood products, such as Jehovah's witnesses, can pose a unique challenge. The objective of this study was to determine rate of adverse post-operative outcomes within 30 days of surgery in Jehovah's witnesses with gynecologic cancer. This was a retrospective cohort study of Jehovah's witnesses undergoing laparotomy or minimally invasive surgery (MIS) for gynecologic cancer at a single institution...
November 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28994558/flexible-co2-laser-fiber-first-look-at-the-learning-curve-required-in-gynecological-laparoscopy-training
#13
Valeria S Vanni, Jessica Ottolina, Giorgio Candotti, Laura M Castellano, Iacopo Tandoi, Francesca DE Stefano, Giorgia Poppi, Stefano Ferrari, Massimo Candiani
BACKGROUND: The advent of flexible CO2 laser fiber to gynecology arena might represent a turning point in the use of laser energy on a large-scale basis in gynecological surgery. However, there might be some concerns regarding the degree of surgical skills required to use the flexible system. The purpose of our study is to evaluate whether flexible CO2 laser fiber is technically accessible. METHODS: Fourteen residents in Obstetrics and Gynecology without surgical experience attending laparoscopic box training with both flexible CO2 laser fiber and traditional line-of-sight CO2 laser using Lumenis AcuPulse Duo CO2 laser (Lumenis, Israel) were prospectively enrolled...
October 9, 2017: Minerva Ginecologica
https://www.readbyqxmd.com/read/28989922/port-site-infiltration-of-local-anesthetic-after-laparoendoscopic-single-site-surgery-for-benign-adnexal-disease
#14
Jung Eun Kim, Seung-Hyuk Shim, Meari Dong, Hyojin Lee, Han Sung Hwang, Han Sung Kwon, Sun Joo Lee, Ji Young Lee, In Sook Sohn, Soo-Nyung Kim, Soon-Beom Kang
OBJECTIVE: To determine whether local bupivacaine injection into the incision site after gynecologic laparoendoscopic single site surgery (LESS) improves postoperative pain. METHODS: This prospective cohort study included consecutive 158 patients who had LESS for benign adnexal disease from March 2013 to December 2015. Chronologically, 82 patients (March 2013 to August 2014) received no bupivacaine (group 1) and 76 (August 2014 to December 2015) received a bupivacaine block (group 2)...
September 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28989920/nomogram-predicting-risk-of-lymphocele-in-gynecologic-cancer-patients-undergoing-pelvic-lymph-node-dissection
#15
Baraem Yoo, Hyojeong Ahn, Miseon Kim, Dong Hoon Suh, Kidong Kim, Jae Hong No, Yong Beom Kim
OBJECTIVE: The purpose of this study is to estimate the risk of postoperative lymphocele development after lymphadenectomy in gynecologic cancer patients through establishing a nomogram. METHODS: We retrospectively reviewed 371 consecutive gynecologic cancer patients undergoing lymphadenectomy between 2009 and 2014. Association of the development of postoperative lymphocele with clinical characteristics was evaluated in univariate and multivariate regression analyses...
September 2017: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/28988885/robotic-surgery-in-gynecology
#16
EDITORIAL
Hextan Y S Ngan, Peter C Lim
No abstract text is available yet for this article.
September 27, 2017: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28988767/could-lymphadenectomy-be-avoided-in-locally-advanced-cervical-cancer-patients-administered-preoperative-chemoradiation-a-large-scale-retrospective-study
#17
Gabriella Ferrandina, Mariagrazia Distefano, Floriana Mascilini, Valerio Gallotta, Vito Chiantera, Francesco Cosentino, Barbara Costantini, Alfredo Ercoli, Luigi Pedone Anchora, Francesco Fanfani, Alessandro Pasquale Margariti, Vincenzo Valentini, Giovanni Scambia
INTRODUCTION: To identify a subset of cervical cancer (CC) patients administered chemoradiation (CT/RT) plus radical surgery (RS), who can be spared lymphadenectomy, and complications. PATIENTS AND METHODS: 430 Stage IB2-IIB patients without LN involvement at imaging were accrued (March 1996-December 2015) at Gynecologic Oncology Unit of the Catholic University of Rome/Campobasso. CT/RT consisted of pelvic irradiation plus cisplatin based chemotherapy. Objective response was evaluated according to RECIST criteria; radical hysterectomy and pelvic ± aortic lymphadenectomy was attempted in patients achieving response or stable disease...
September 23, 2017: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28988685/socioeconomic-disparities-affect-survival-in-malignant-ovarian-germ-cell-tumors-in-aya-population
#18
L V Bownes, L L Stafman, I I Maizlin, M Dellinger, K W Gow, A B Goldin, M Goldfarb, M Langer, M V Raval, J J Doski, J G Nuchtern, S A Vasudevan, E A Beierle
BACKGROUND: Malignant ovarian germ cell tumors (MOGCTs) are a rare form of ovarian malignancy. Socioeconomic status (SES) has been shown to affect survival in several gynecologic cancers. We examined whether SES impacted survival in adolescent and young adults (AYAs) with MOGCT. MATERIALS AND METHODS: The National Cancer Data Base was used to identify AYAs (aged 15-39 years) with MOGCT from 1998 to 2012. Three SES surrogate variables identified were as follows: insurance type, income quartile, and education quartile...
October 5, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28988359/patient-reported-outcomes-after-sacrospinous-fixation-of-vault-prolapse-with-a-suturing-device-a-retrospective-national-cohort-study
#19
Jennifer Campbell, Corinne Pedroletti, Linn Ekhed, Emil Nüssler, Annika Strandell
INTRODUCTION AND HYPOTHESIS: Innovations in suturing devices have facilitated sacrospinous ligament fixation (SSF) for the correction of vaginal vault prolapse. It is uncertain if outcomes using suturing devices differ from those using a traditional suturing technique. We hypothesize that no difference exists in the efficacy and safety 1 year after SSF for vault prolapse performed with suturing devices or using a traditional technique. The objective was to compare SSF using a suturing device with traditional SSF for the treatment of vault prolapse, regarding symptoms of prolapse recurrence, patient satisfaction, incidence of re-operation, and complications 1 year postoperatively...
October 7, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28988254/preoperative-thrombocytosis-as-a-prognostic-factor-in-endometrioid-type-endometrial-carcinoma
#20
Ahmed Abu-Zaid, Mohannad Alsabban, Mohammed Abuzaid, Osama AlOmar, Hany Salem, Ismail A Al-Badawi
BACKGROUND: The impact of preoperative thrombocytosis as a prognostic factor in endometrial carcinoma (EC) remains uncertain and has never been examined in Saudi Arabia. OBJECTIVES: To determine the prevalence of preoperative thrombocytosis (platelet count > 400 000/ μL), and its prognostic significance for clinicopathological factors and survival in Saudi patients with endometrioid-type EC. DESIGN: A retrospective cross-sectional study from January 2010 to December 2013...
September 2017: Annals of Saudi Medicine
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