keyword
MENU ▼
Read by QxMD icon Read
search

Old age breast cancer

keyword
https://www.readbyqxmd.com/read/29772993/shoulder-lesion-in-a-69-year-old-woman
#1
Andrew J Hayden, Srinivas Kolla, Adele L Boskey, Steven Burekhovich, Chuanyong Lu, Michael Stracher, Aditya V Maheshwari
Milwaukee Shoulder Syndrome (MSS) is a painful progressive arthropathy in which hydroxyapatite crystal deposition in synovial tissue induces lysosomal release of collagenase and neutral proteases. These enzymes are destructive to periarticular tissue, including the synovium, articular cartilage, rotator cuff muscles, and the intrasynovial cortical bone. MSS predominantly occurring in women (90%) over the age of 70 years of age with a clinical history marked by recurrent joint effusions and pain, which classically worsens at night...
2018: Journal of Long-term Effects of Medical Implants
https://www.readbyqxmd.com/read/29767749/association-of-brca2-k3326-with-small-cell-lung-cancer-and-squamous-cell-cancer-of-the-skin
#2
Thorunn Rafnar, Gudbjorg R Sigurjonsdottir, Simon N Stacey, Gisli Halldorsson, Patrick Sulem, Luba M Pardo, Hannes Helgason, Stefan T Sigurdsson, Thorkell Gudjonsson, Laufey Tryggvadottir, Gudridur H Olafsdottir, Jon G Jonasson, Kristin Alexiusdottir, Asgeir Sigurdsson, Julius Gudmundsson, Jona Saemundsdottir, Jon K Sigurdsson, Hrefna Johannsdottir, Andre Uitterlinden, Sita H Vermeulen, Tessel E Galesloot, Dawn C Allain, Martin Lacko, Bardur Sigurgeirsson, Kristin Thorisdottir, Oskar T Johannsson, Fridbjorn Sigurdsson, Gunnar B Ragnarsson, Helgi Isaksson, Hronn Hardardottir, Tomas Gudbjartsson, Daniel F Gudbjartsson, Gisli Masson, Lambertus A M L Kiemeney, Amanda Ewart Toland, Tamar Nijsten, Wilbert H M Peters, Jon H Olafsson, Steinn Jonsson, Unnur Thorsteinsdottir, Gudmar Thorleifsson, Kari Stefansson
Background: Most pathogenic mutations in the BRCA2 gene carry a high risk of hereditary breast and ovarian cancer (HBOC). However, a stop-gain mutation, K3326* (rs11571833), confers risk of lung cancer and cancers of the upper-aero-digestive tract but only a modest risk of breast or ovarian cancer. The Icelandic population provides an opportunity for comprehensive characterization of the cancer risk profiles of K3326* and HBOC mutations because a single mutation, BRCA2 999del5, is responsible for almost all BRCA2-related HBOC in the population...
May 14, 2018: Journal of the National Cancer Institute
https://www.readbyqxmd.com/read/29763858/the-oncologic-impact-of-hormone-replacement-therapy-in-premenopausal-breast-cancer-survivors-a-systematic-review
#3
REVIEW
Yimeng Wang, Naomi Lewin, Yazan Qaoud, A Nikoo Rajaee, Adena S Scheer
SYNOPSIS: This is the first systematic review to investigate the risk of recurrence in breast cancer survivors <50 years old who have used hormone replacement therapy (HRT). BACKGROUND: The risk of HRT in premenopausal breast cancer survivors is unclear. Due to the higher incidence of estrogen receptor negative tumours in women <50, the potential for HRT to promote breast cancer recurrence may differ from older age groups. METHODS: We performed a search of Medline, EMBASE and CINAHL through June 2016...
May 12, 2018: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29751600/inflamed-phylloides-tumour-in-a-girl-a-challenging-diagnosis-in-paediatric-breast-lesions
#4
Ilaria Testa, Cristina Salvatori, Marco Prestipino, Maria Elena Laurenti, Paolo Gerli, Giuseppe Di Cara, Nicola Principi, Susanna Esposito, Mirko Bertozzi
Introduction : Phylloides tumours (PTs) are rare fibroepithelial neoplasms that account for 0.3⁻0.9% of all breast tumours. These tumours typically occur in women aged 30⁻70 years. The occurrence of these tumours in older children and adolescents poses particular diagnostic and therapeutic problems. However, early diagnosis is mandatory because although most of the cases of PTs in children are benign, the borderline and malignant cases with potential negative outcomes cannot be excluded. Case presentation : A 12-year-old girl presented at the Paediatric Emergency Department for hyperaemia and warmth of the left breast that occurred a few days prior without fever...
May 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29747486/omitting-adjuvant-radiotherapy-for-hormone-receptor%C3%A2-positive-early-stage-breast-cancer-in-old-age-a-propensity-score-matched-seer-analysis
#5
Yi-Jun Kim, Kyung Hwan Shin, Kyubo Kim
Purpose: The purpose of this study was to investigate the non-inferiority of omitting radiotherapy (RT) after breast-conserving surgery (BCS) for hormone receptor (HR)‒positive T1N0 breast cancer in elderly women. Materials and Methods: From 2004 to 2014, HR-positive T1N0 breast cancer patients aged 50 years or older and receiving BCS were retrieved from the Surveillance, Epidemiology, and End. Results: 18 database. After propensity score matching between the no-RT and RT groups, univariate and multivariate analyses were performed...
May 10, 2018: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/29733019/prognostic-factors-of-treatment-failure-for-early-breast-cancer-after-breast-conserving-surgery
#6
Mohammad Aldaqaf, Eugen Bratucu
Introduction: Breast cancer is the most common cancer in women in developed Western countries and is becoming even more significant in many developing countries. Breast conserving surgery (BCS) has become the gold standard for patients with early breast cancer (EBC) (Stage I, II) with an appropriate patient selection. Important risk factors for treatment failure, include margin status, age, tumour multicentricity and use of radiotherapy and adjuvant hormone therapy. AIM: To establish the prognostic variables for ipsilateral breast tumour recurrence (IBTR) in EBC after BCS and the survival rate...
March 2018: Chirurgia
https://www.readbyqxmd.com/read/29731127/the-need-for-triple-assessment-and-predictors-for-diagnosis-of-breast-cancer-in-patients-40-years-of-age
#7
F A K Mazari, N Sharma, D Reid, K Horgan
AIM: To assess the safety of selective use of triple assessment with omission of radiological assessment proposed in patients <40-years old. MATERIALS AND METHODS: Data were collected retrospectively for all patients seen in the one-stop breast clinic between January 2014 and August 2015. Demographics, symptoms, diagnostics, and treatment details were recorded. Subgroup and logistic regression analysis was performed to identify predictors for breast cancer. RESULTS: Of the 3,305 patients included, 95...
May 3, 2018: Clinical Radiology
https://www.readbyqxmd.com/read/29723101/breast-cancer-in-an-18-year-old-female-a-fatal-case-report-and-literature-review
#8
Maciej Jóźwik, Renata Posmyk, Marcin Jóźwik, Andrzej Semczuk, Magdalena Gogiel-Shields, Marta Kuś-Słowińska, Magdalena Garbowicz, Mark Klukowski, Jacek Wojciechowicz
Breast cancer (BC) is the most frequent malignancy in both pre- and postmenopausal women. However, it is exceedingly rare in very young patients, and especially in adolescents. Herein, we report a case of an 18-year-old female diagnosed with invasive BC. The proband had been found to be negative for BC in close family members. A common BC genetic screening test for the Polish population did not detect any known founder mutations in the BRCA1 gene. Further evaluation identified a p.Ile157Thr (I157T) mutation in the CHEK2 gene, a p...
May 3, 2018: Cancer Biology & Therapy
https://www.readbyqxmd.com/read/29721647/cardiac-autonomic-modulation-impairments-in-advanced-breast-cancer-patients
#9
Claudia Arab, Luiz Carlos Marques Vanderlei, Laércio da Silva Paiva, Kyle Levi Fulghum, Carlos Elias Fristachi, Afonso Celso Pinto Nazario, Simone Elias, Luiz Henrique Gebrim, Celso Ferreira Filho, Yori Gidron, Celso Ferreira
AIM: To compare cardiac autonomic modulation in early- versus advanced-stage breast cancer patients before any type of cancer treatment and investigate associated factors. METHODS AND RESULTS: This cross-sectional study included women (30-69 years old) with primary diagnosis of breast cancer and women with benign breast tumors. We evaluated cardiac modulation by heart rate variability and assessed factors of anxiety, depression, physical activity, and other relevant medical variables...
May 2, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29716543/characteristics-of-patients-with-missing-information-on-stage-a-population-based-study-of-patients-diagnosed-with-colon-lung-or-breast-cancer-in-england-in-2013
#10
Chiara Di Girolamo, Sarah Walters, Sara Benitez Majano, Bernard Rachet, Michel P Coleman, Edmund Njeru Njagi, Melanie Morris
BACKGROUND: Stage is a key predictor of cancer survival. Complete cancer staging is vital for understanding outcomes at population level and monitoring the efficacy of early diagnosis initiatives. Cancer registries usually collect details of the disease extent but staging information may be missing because a stage was never assigned to a patient or because it was not included in cancer registration records. Missing stage information introduce methodological difficulties for analysis and interpretation of results...
May 2, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29697934/5-alpha-reductase-inhibitors-and-risk-of-male-breast-cancer-a-systematic-review-and-meta-analysis
#11
REVIEW
Jiamin Wang, Shankun Zhao, Lianmin Luo, Ermao Li, Xiaohang Li, ZhiGang Zhao
OBJECTIVE: To assess the relationship between 5α-reductase inhibitors (5ARIs) and the risk of male breast cancer (MBC). MATERIAL AND METHODS: We systematically searched Medline via PubMed, Embase and the Cochrane Library Central Register up to May 2017 to identify published articles related to 5ARIs and the risk of MBC. RESULTS: Summary effect estimates were calculated by a random-effect model, and tests for multivariable-unadjusted pooled risk ratios (RR) and heterogeneity, as well as the sensitivity analyses were conducted to assess publication bias...
April 10, 2018: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/29689595/potentially-inappropriate-medication-use-in-older-patients-with-breast-and-colorectal-cancer
#12
Meghan S Karuturi, Holly M Holmes, Xiudong Lei, Michael Johnson, Carlos H Barcenas, Scott B Cantor, Gary E Gallick, Robert C Bast, Sharon H Giordano
BACKGROUND: The objective of this study was to determine patient characteristics associated with potentially inappropriate medication (PIM) use and its impact on outcomes for patients with breast or colorectal cancer receiving adjuvant chemotherapy. METHODS: The Surveillance, Epidemiology, and End Results database, linked to Medicare claims, was used. The cohort included patients who were 66 years old or older and were diagnosed with stage II or III breast or colorectal cancer between July 1, 2007, and December 31, 2009...
April 24, 2018: Cancer
https://www.readbyqxmd.com/read/29683228/relationships-between-self-reported-sleep-quality-components-and-cognitive-functioning-in-breast-cancer-survivors-up-to-10-years-following-chemotherapy
#13
Ashley M Henneghan, Patricia Carter, Alexa Stuifbergan, Brennan Parmelee, Shelli Kesler
OBJECTIVE: Links have been made between aspects of sleep quality and cognitive function in breast cancer survivors (BCS), but findings are heterogeneous. The objective of this study is to examine relationships between specific sleep quality components (latency, duration, efficiency, daytime sleepiness, sleep disturbance, use of sleep aids) and cognitive impairment (performance and perceived), and determine which sleep quality components are the most significant contributors to cognitive impairments in BCS 6 months to 10 years post chemotherapy...
April 23, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29671222/prognostic-value-of-ki-67-according-to-age-in-patients-with-triple-negative-breast-cancer
#14
V Zenzola, M A Cabezas-Quintario, M Arguelles, E Pérez-Fernández, Y Izarzugaza, A Correa, J García-Foncillas
PURPOSE: The prognostic value of Ki-67 in triple-negative breast cancer (TNBC) is yet unclear because the cut-off points employed differ widely and its predictive effect may vary according to age. The purpose of this study was to analyze the role of Ki-67 among patients with TNBC, and determine the optimal Ki-67 cut-off point to demonstrate its prognostic relevance associated with patient age and treatment strategy. METHODS/PATIENTS: 201 consecutive patients treated for primary TNBC from 1999 to 2014 were analyzed...
April 18, 2018: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/29660894/overall-survival-of-elderly-patients-with-breast-cancer-is-not-related-to-breast-cancer-specific-survival-a-single-institution-experience-in-japan
#15
Haruko Takuwa, Wakako Tsuji, Fumiaki Yotsumoto
BACKGROUND: As the aging population grows, the number of elderly breast cancer patients has rapidly increased especially in Japan; a suitable treatment for elderly patients, considering chronic comorbidities and treatment tolerance, is urgently needed. METHODS: In this retrospective study, 286 elderly breast cancer patients were investigated. Tumor characteristics and survival outcome were compared between 70-79-year-old and ≥ 80-year-old groups. Disease-free survival, overall survival, and breast cancer-specific survival were compared, and the effect of variables was analyzed statistically...
April 5, 2018: Breast Disease
https://www.readbyqxmd.com/read/29650388/evaluation-at-3-years-of-concurrent-bevacizumab-and-radiotherapy-for-breast-cancer-results-of-a-prospective-study
#16
A Dautruche, L Belin, P Cottu, P Bontemps, C Lemanski, B de la Lande, P Baumann, F Missohou, C Lévy, K Peignaux, A Reynaud-Bougnoux, F Denis, A Gobillion, V Pernin, Y Kirova
PURPOSE: To determine the 3 years late toxicity among patients with non-metastatic breast cancer who received concurrent bevacizumab and locoregional radiotherapy. MATERIAL AND METHODS: This is a single-arm, multicentre, prospective study, of the toxicity of adjuvant concomitant association of bevacizumab and radiotherapy in patients with breast cancer. Toxicity was assessed by the Common Terminology Criteria for Adverse Events version 3.0 during the radiotherapy and follow-up clinics at 12 and 36 months after its completion...
April 9, 2018: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/29629888/comparison-of-the-ultrasound-guided-tru-cut-biopsy-with-postoperative-histopathology-results-in-patients-with-breast-mass
#17
Mehmet Emin Günes
AIM: We aimed to compare the tru-cut biopsy and postoperative pathology results of breast lesions with suspicion of malignancy. Furthermore we aimed to determine the efficacy, specificity and sensitivity of the tru-cut biopsy. METHODOLOGY: 140 patients who were operated due to breast mass following tru-cut biopsy were retrospectively evaluated. Patients' demographic characteristics, imaging findings, biopsy and histopathology results were compared. RESULTS: The mean age of 140 patients was 51...
2018: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29629810/tomosynthesis-impact-on-breast-cancer-screening-in-patients-younger-than-50-years-old
#18
Stephen L Rose, Julie L Shisler
OBJECTIVE: The question of benefits versus harms of breast cancer screening for women younger than 50 years old has been the subject of debate. We investigate if the addition of tomosynthesis to mammography improves screening performance outcomes for women in this age group. MATERIALS AND METHODS: Screening performance for 59,921 patients (41,542 digital mammography and 18,379 tomosynthesis) younger than 50 years old was collected from a community-based screening network from January 1, 2015, to December 31, 2015...
April 9, 2018: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/29628978/basic-findings-regarding-breast-cancer-in-korea-in-2015-data-from-a-breast-cancer-registry
#19
REVIEW
Sang Yull Kang, Yoo Seok Kim, Zisun Kim, Hyun-Yul Kim, Se Kyung Lee, Kyu-Won Jung, Hyun Jo Youn
The Korean Breast Cancer Society (KBCS) has established a nationwide breast cancer database using an online registration program in 1996. The present study aimed to analyze the basic findings and trends of breast cancer in Korea in 2015 using the data provided by the Korea Central Cancer Registry and the KBCS. In 2015, a total of 22,550 patients were newly diagnosed with breast cancer, of which 3,331 were carcinoma in situ cases and 19,219 were invasive cancer cases. The incidence rate of breast cancer in Korea has steadily increased since the nationwide database was established, and the crude rate and age-standardized rate including that of carcinoma in situ , were 88...
March 2018: Journal of Breast Cancer
https://www.readbyqxmd.com/read/29625622/effect-of-exercise-on-pain-and-functional-capacity-in-breast-cancer-patients
#20
Andréa Dias Reis, Paula Tamara Vieira Teixeira Pereira, Renata Rodrigues Diniz, Jurema Gonçalves Lopes de Castro Filha, Alcione Miranda Dos Santos, Bianca Trovello Ramallo, Florentino Assenço Alves Filho, Francisco Navarro, João Batista Santos Garcia
PURPOSE: To assess the influence of combined training on pain, fatigue, maximal oxygen uptake (VO2 max), body mass index (BMI), flexibility, and strength in patients with breast cancer. METHODS: A controlled pilot study with 28 patients undergoing chemotherapy, radiation therapy, and clinical observation in a renowned cancer treatment center; the patients were aged from 30 to 59 years old and were not engaged in physical training for three months previously. The Study Group (SG) underwent 12 weeks of training, including three 60-min sessions of aerobic exercise and resistance training, and two sessions of flexibility training per week; each flexibility exercise lasted 20 s and was performed in sets of three repetitions...
April 6, 2018: Health and Quality of Life Outcomes
keyword
keyword
43935
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"