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Old age breast cancer

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https://www.readbyqxmd.com/read/29346353/the-burden-of-cancer-in-25-29-year-olds-in-new-zealand-a-case-for-a-wider-adolescent-and-young-adult-age-range
#1
Kirsten R Ballantine, Victoria Utley, Heidi Watson, Michael J Sullivan, Ruth Spearing
AIMS: New Zealand currently defines the adolescent and young adult (AYA) group for cancer services as young people 12-24 years of age, while other countries favour a designation of 15-29 years. This study was undertaken to compare cancer incidence and survival among 25-29 year olds to New Zealand's younger AYA population and to assess survival for our 15-29 year population against international benchmarks. METHODS: Diagnostic and demographic information for cancer registrations between 2000 and 2009 for 25-29 year olds was obtained from the New Zealand Cancer Registry...
January 19, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29344741/assessment-of-potential-risk-factors-for-breast-cancer-in-a-population-in-southern-brazil
#2
Juliana Zeni Breyer, Eliana Marcia Wendland, Natália Luiza Kops, Maira Caleffi, Luciano Serpa Hammes
PURPOSE: The aim of this study is to assess potential risk factors for breast cancer in a population in Southern Brazil and build a multivariate logistic model using these factors for breast cancer risk prediction. METHODS: A total of 4242 women between 40 and 69 years of age without a history of breast cancer were selected at primary healthcare facilities in Porto Alegre and submitted to mammographic screening. They were evaluated for potential risk factors. RESULTS: In all, 73 participants among the 4242 women had a breast cancer diagnosis during the follow-up of the project (10 years)...
January 17, 2018: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29339357/family-history-and-risk-of-second-primary-breast-cancer-after-in-situ-breast-carcinoma
#3
Michelle L Baglia, Mei-Tzu C Tang, Kathleen E Malone, Peggy Porter, Christopher I Li
BACKGROUND: Incidence rates of in situ breast carcinomas have increased due to widespread adoption of mammography. Very little is known about why some women with in situ breast cancer later develop second primary breast cancers. METHODS: In this population-based nested case-control study among in situ breast cancer survivors, including 539 cases with a second primary breast cancer and 994 matched controls, we evaluated the association between first degree family history of breast cancer and risk of developing a second primary breast cancer...
January 16, 2018: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29330268/pelvic-and-buttock-hypoplasia-reconstructed-with-anatomical-breast-implants
#4
Felicity Page, Ayad Harb, Garth Titley
Radiation therapy is used in the management of a number of childhood cancers and can have significant effects on skeletal growth. We present the case of a 35-year-old woman who developed a hypoplastic pelvis and buttocks following radiotherapy for rhabdomyosarcoma of the vagina at the age of 2. At the age of 25, the patient underwent bilateral buttock augmentation with a two-stage reconstruction using tissue expansion followed by definitive augmentation with anatomical breast implant insertion. The patient continues to have a satisfactory outcome 10 years following reconstruction, having undergone a single uplift procedure and exchange of implants through the original incision 9 years postoperatively...
January 12, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29305131/prevalence-and-predictors-of-low-serum-25-hydroxyvitamin-d-among-female-african-american-breast-cancer-survivors
#5
Patricia Sheean, Claudia Arroyo, Jennifer Woo, Linda Schiffer, Melinda Stolley
BACKGROUND: African-American breast cancer survivors commonly demonstrate low serum 25-hydroxyvitamin D (25(OH)D). Decreased cutaneous conversion, high levels of adiposity, and even breast cancer treatment may influence vitamin D status. Previous investigations have analyzed African-American women in aggregate with other breast cancer survivors and have not comprehensively addressed these influential factors. OBJECTIVES: To determine the prevalence of low serum 25(OH)D in an exclusively African-American cohort of female breast cancer survivors with overweight/obesity and to evaluate the role of ultraviolet (UV) light exposure, body composition, and dietary sources of vitamin D on serum 25(OH)D levels...
January 2, 2018: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29304140/long-term-effects-of-manual-lymphatic-drainage-and-active-exercises-on-physical-morbidities-lymphoscintigraphy-parameters-and-lymphedema-formation-in-patients-operated-due-to-breast-cancer-a-clinical-trial
#6
Mariana Maia Freire de Oliveira, Maria Salete Costa Gurgel, Bárbara Juarez Amorim, Celso Dario Ramos, Sophie Derchain, Natachie Furlan-Santos, César Cabello Dos Santos, Luís Otávio Sarian
PURPOSE: evaluate whether manual lymphatic drainage (MLD) or active exercise (AE) is associated with shoulder range of motion (ROM), wound complication and changes in the lymphatic parameters after breast cancer (BC) surgery and whether these parameters have an association with lymphedema formation in the long run. METHODS: Clinical trial with 106 women undergoing radical BC surgery, in the Women's Integrated Healthcare Center-University of Campinas. Women were matched for staging, age and body mass index and were allocated to performed AE or MLD, 2 weekly sessions during one month after surgery...
2018: PloS One
https://www.readbyqxmd.com/read/29295635/real-world-utilization-of-molecular-diagnostic-testing-and-matched-drug-therapies-in-the-treatment-of-metastatic-cancers
#7
Anita Chawla, Miranda Peeples, Nanxin Li, Rachel Anhorn, Jason Ryan, James Signorovitch
AIMS: To assess the frequency of biopsies and molecular diagnostic testing (human DNA/RNA analysis), anti-cancer drug use (genomically-matched targeted therapy [GMTT], unmatched targeted therapy [UTT], endocrine therapy [ET], and chemotherapy [CT]), and medical service costs among adults with metastatic cancer. METHODS: Adults diagnosed with metastatic breast, non-small cell lung (NSCLC), colorectal, head and neck, ovarian, and uterine cancer (2010Q1-2015Q1) were identified in the OptumHealth Care Solutions claims database and followed from first metastatic diagnosis for ≥1 month and until end of data availability...
January 3, 2018: Journal of Medical Economics
https://www.readbyqxmd.com/read/29290274/predictors-of-psychological-distress-trajectories-in-the-first-year-after-a-breast-cancer-diagnosis
#8
Jin-Hee Park, Mison Chun, Yong-Sik Jung, Sun Hyoung Bae
PURPOSE: Psychological distress is a significant and ongoing problem for breast cancer. These mental health problems are often neglected as they are not always properly understood. This study was performed to explore the trajectory of psychological distress over 1 year since breast cancer surgery and to identify the associated factors for the trajectory. METHODS: One hundred seventeen women who underwent surgery for breast cancer completed the psychological distress thermometer and problem lists from after surgery to 12 months after surgery...
December 2017: Asian Nursing Research
https://www.readbyqxmd.com/read/29287894/-monitoring-of-hypertension-in-patients-orally-treated-by-angiogenesis-inhibitor-in-daily-practice
#9
Lisa Belaid, Sahar Bayat-Makoei, Brigitte Laguerre, Cécile Vigneau
OBJECTIVE: The aim of this study is to measure the monitoring and the incidence of renovascular effects of angiogenesis inhibitors in real population. METHOD: Are included in this descriptive, monocentric, practical study, patients of 18 years old and more, orally treated by angiogenesis inhibitors and monitored in consultation by clinician nurses. The main interest variable is the incidence of hypertension at three months of treatment. RESULTS: From January, 2011 to July, 2014, 324 patients have been included, whose 53% are men...
December 26, 2017: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29274475/breast-cancer-in-octogenarian-are-we-doing-our-best-a-population-registry-based-study
#10
David Martinez-Ramos, Laura Simon-Monterde, Raquel Queralt-Martin, Consuelo Suelves-Piqueres, Pedro Menor-Duran, Javier Escrig-Sos
BACKGROUND: The number of old people with breast cancer is estimated to increase during the next years in developed countries. However, management of breast cancer in octogenarians is not well established. The main objective was to evaluate if patients older than 80 years with breast cancer are receiving the most convenient treatment by using a population registry cancer analysis. PATIENTS AND METHODS: A retrospective analysis of a population cancer registry was designed...
December 20, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/29261685/mortality-reductions-due-to-mammography-screening-contemporary-population-based-data
#11
James A Hanley, Ailish Hannigan, Katie M O'Brien
Our objective was to compare breast cancer mortality in two regions of the Republic of Ireland that introduced a screening programme eight years apart, and to estimate the steady-state mortality deficits the programme will produce. We carried out age- and year-matched between-region comparison of breast cancer mortality rates, and of incidence rates of stage 2-4 breast cancer, in the eligible cohorts. The regions comprised counties that, beginning in early 2000 (region 1) and late 2007 (region 2), invited women aged 50-64 to biennial mammography screening...
2017: PloS One
https://www.readbyqxmd.com/read/29247440/analysis-of-breast-cancer-in-young-women-in-the-department-of-defense-dod-database
#12
Alexandra S Zimmer, Kangmin Zhu, Patricia S Steeg, Alex Wu, Margaret E Gatti-Mays, Sanaz Soltani, Jeremy G Perkins, Stephanie Shao, Derek Brown, Matthew Georg, Hai Hu, Craig D Shriver, Stanley Lipkowitz
PURPOSE: Breast tumors from young women under the age of 40 account for approximately 7% of cases and have a poor prognosis independent of established prognostic factors. We evaluated the patient population served by the Military Health System, where a disproportionate number of breast cancer cases in young women are seen and treated in a single universal coverage healthcare system. METHODS: The Military Health System Repository and the DoD Central Registration databases were used to identify female breast cancer patients diagnosed or treated at military treatment facilities from 1998 to 2007...
December 15, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29226849/assessment-of-global-and-local-region-based-bilateral-mammographic-feature-asymmetry-to-predict-short-term-breast-cancer-risk
#13
Yane Li, Ming Fan, Hu Cheng, Peng Zhang, Bin Zheng, Lihua Li
This study aims to develop and test a new imaging marker-based short-term breast cancer risk prediction model. An age-matched dataset of 566 screening mammography cases was used. All "prior" images acquired in the two screening series were negative, while in the "current" screening images, 283 cases were positive for cancer and 283 cases remained negative. For each case, two bilateral cranio-caudal view mammograms acquired from the "prior" negative screenings were selected and processed by a computer-aided image processing scheme, which segmented the entire breast area into 9 strip-based local regions, extracted the element regions using difference of Gaussian filters, and computed both global- and local-based bilateral asymmetrical image features...
December 11, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29221517/urban-rural-disparity-in-helicobacter-pylori-infection-related-upper-gastrointestinal-cancer-in-china-and-the-decreasing-trend-in-parallel-with-socioeconomic-development-and-urbanization-in-an-endemic-area
#14
Xiaoduo Wen, Denggui Wen, Yi Yang, Yuetong Chen, Guiying Wang, Baoen Shan
BACKGROUND: Globally China has the largest urban-rural disparity in socioeconomic development, and the urban-rural difference in upper gastrointestinal cancer (UGIC) is similar to the difference between developed and developing countries. OBJECTIVES: To describe urban-rural disparity in UGIC and to emphasize prevention by socioeconomic development and urbanization in China. METHODS: Age-standardized incidence rates (ASRs) of cancers in 2012 were compared between urban Shijiazhuang city and rural Shexian County, and trends from 2000-2015 in Shexian County were analyzed...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29211842/maternal-age-at-birth-and-daughters-subsequent-childlessness
#15
O Basso, C R Weinberg, A A D'Aloisio, D P Sandler
STUDY QUESTION: Does maternal age at a daughter's birth predict her subsequent probability of lifelong childlessness? SUMMARY ANSWER: In this study population, women born to older mothers were more likely to be childless. WHAT IS KNOWN ALREADY: Although maternal age at childbearing is increasing in many countries, there is limited evidence on whether being born to older parents may influence offspring fertility. STUDY DESIGN SIZE AND DURATION: This analysis included 43 135 women from the US-based Sister Study, a cohort study of 50 884 sisters of women with breast cancer recruited between 2003 and 2009...
December 4, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29208778/comparison-of-the-ultrasound-guided-tru-cut-biopsy-with-postoperative-histopathology-results-in-patients-with-breast-mass
#16
Mehmet Emin Gunes
AIM: We aimed to compare the tru-cut biopsy and postoperative pathology results of breast lesions with suspicion of malignancy. Furthermore we aimed to determine the efficacy, specificity and sensitivity of the tru-cut biopsy. METHODOLOGY: 140 patients who were operated due to breast mass following tru-cut biopsy were retrospectively evalu-ated. Patients' demographic characteristics, imaging findings, biopsy and histopathology results were compared. RESULTS: The mean age of 140 patients was 51...
November 29, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/29207007/fertility-preservation-in-women-harboring-deleterious-brca-mutations-ready-for-prime-time
#17
Fedro Alessandro Peccatori, Giorgia Mangili, Alice Bergamini, Francesca Filippi, Fabio Martinelli, Federica Ferrari, Stefania Noli, Emanuela Rabaiotti, Massimo Candiani, Edgardo Somigliana
Fertility issues have become critical in the management and counseling of BRCA mutation carriers. In this setting four points deserve consideration. (1) Women in general lose their ability to conceive at a mean age of 41 years, thus the suggested policy of prophylactic bilateral salpingo-oophorectomy at age 40 for BRCA mutation carriers does not affect the chances of natural pregnancy. Conversely, if the procedure is chosen at 35 years old, oocyte cryopreservation prior to surgery should be considered. (2) Some evidence suggests that ovarian reserve may actually be partly reduced in BRCA mutations carriers and that the mutation may affect ovarian responsiveness to stimulation...
December 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29205296/impact-of-latency-time-on-survival-for-adolescents-and-young-adults-with-a-second-primary-malignancy
#18
Melanie Goldfarb, Aaron S Rosenberg, Qian Li, Theresa H M Keegan
BACKGROUND: The adverse impact of second primary malignancies (SPMs) on survival is substantial for adolescents and young adults (AYAs; ie, those 15-39 years old). No studies have evaluated whether the latency time between the first malignancy (the primary malignancy [PM]) and the SPM affects cancer-specific survival (CSS). METHODS: A multivariate Cox proportional hazards regression with Surveillance, Epidemiology, and End Results data for 13 regions from 1992 to 2008 was used to ascertain whether the latency time (1-5 vs ≥ 6 years) to the development of an SPM affected the CSS and overall survival with respect to either the PM or SPM for AYAs with common SPMs...
December 4, 2017: Cancer
https://www.readbyqxmd.com/read/29200695/metaplastic-carcinoma-of-breast-and-neurofibromatosis-1-a-rare-association
#19
Gnanapriya Vellaisamy, Suravi Mohanty, Pritilata Rout, Suraj Manjunath
Neurofibromatosis 1 (NF1) patients are generally at higher risk of developing common malignant tumors such as brain and soft tissue tumors. These patients are 5-fold increased the risk of developing breast cancer by the age of 50 years after that the risk remains the same. The most common reported cancer is infiltrating duct carcinoma. We report a case of 61-year-old female with NF1 presented with pain and breast lump for the past 2 months. On mammography, a retroareolar solid cystic lesion measuring 32 mm × 30 mm × 30 mm was noted which was definitive for malignancy...
July 2017: Indian Journal of Medical and Paediatric Oncology
https://www.readbyqxmd.com/read/29183534/papillary-breast-lesions-association-with-malignancy-and-upgrade-rates-on-surgical-excision
#20
Hanh-Tam Tran, Asma Mursleen, Sahar Mirpour, Omar Ghanem, Maen J Farha
Intraductal papilloma falls under the category of benign breast mass. However, recent studies show that it can harbor occult carcinoma. The management of benign intraductal papilloma remains controversial because of its nonspecific radiologic and histological findings, as well as its association with surrounding malignant pathology. The purpose of this study is to investigate upgrade rates of a benign intraductal papilloma on surgical excision and the need for surgical excision of papillary lesions diagnosed at core needle biopsy...
November 1, 2017: American Surgeon
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