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https://www.readbyqxmd.com/read/29691360/radiation-dose-in-breast-imaging
#1
Teresa G Odle
Screening mammography introduces low doses of radiation per examination and in regular intervals over decades for women who have annual screening. Further, advanced breast imaging modalities and follow-up imaging methods contribute to additional radiation exposure in radiosensitive breast tissue. This article reviews the effects of radiation on the breasts, summarizes dose measurements and estimates for breast imaging modalities, and discusses efforts to optimize dose in breast imaging.
March 2018: Radiologic Technology
https://www.readbyqxmd.com/read/29691345/evaluating-mammographer-acceptance-of-mammorisk-software
#2
Jean Weigert, Nancy Cavanaugh, Talong Ju
PURPOSE: To evaluate mammographers' acceptance of the breast cancer risk assessment software tool MammoRisk (Statlife) in the clinical setting. METHODS: During a 6-month period, 1200 women undergoing routine mammography examinations at a regional, outpatient, comprehensive breast imaging center were assessed for breast cancer risk by mammographers who used the MammoRisk software. At the end of the 6-month period, the mammographers (N = 11) completed an 8-question survey on their willingness to the use of the software in the clinical setting...
March 2018: Radiologic Technology
https://www.readbyqxmd.com/read/29691123/a-computer-aided-detection-of-the-architectural-distortion-in-digital-mammograms-using-the-fractal-dimension-measurements-of-bemd
#3
Imad Zyout, Roberto Togneri
Achieving a high performance for the detection and characterization of architectural distortion in screening mammograms is important for an efficient breast cancer early detection. Viewing a mammogram image as a rough surface that can be described using the fractal theory is a well-recognized approach. This paper presents a new fractal-based computer-aided detection (CAD) algorithm for characterizing various breast tissues in screening mammograms with a particular focus on distinguishing between architectural distortion and normal breast parenchyma...
April 3, 2018: Computerized Medical Imaging and Graphics: the Official Journal of the Computerized Medical Imaging Society
https://www.readbyqxmd.com/read/29691075/estro-acrop-guideline-interstitial-multi-catheter-breast-brachytherapy-as-accelerated-partial-breast-irradiation-alone-or-as-boost-gec-estro-breast-cancer-working-group-practical-recommendations
#4
Vratislav Strnad, Tibor Major, Csaba Polgar, Michael Lotter, Jose-Luis Guinot, Cristina Gutierrez-Miguelez, Razvan Galalae, Erik Van Limbergen, Benjamin Guix, Peter Niehoff, Kristina Lössl, Jean-Michel Hannoun-Levi
PURPOSE: This consensus statement from the Breast Cancer Working Group of Groupe Européen de Curiethérapie of European Society for Radiotherapy and Oncology (GEC-ESTRO) aims at generating practical guidelines for multi-catheter image-guided brachytherapy in the conservative management of breast cancer patients used for either Accelerated Partial Breast Irradiation (APBI) or for a breast boost. METHODS: Recent advances in techniques of multi-catheter brachytherapy were summarized and all the relevant literature was reviewed by a panel of experts...
April 21, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29690864/radiogenic-angiosarcoma-of-the-breast-case-report-and-systematic-review-of-the-literature
#5
Askin Dogan, Peter Kern, Beate Schultheis, Günther Häusler, Günther A Rezniczek, Clemens B Tempfer
BACKGROUND: Radiogenic angiosarcoma of the breast (RASB) is a rare late sequela of local irradiation of the breast or chest wall after breast cancer. The prognosis of women with RASB is poor and there is no standardized therapy for this type of malignancy. CASE PRESENTATION: We present the case of a 54 year old woman with RASB (poorly differentiated angiosarcoma of the left breast; pT1, pNX, M0, L0, V0) and a history of invasive-ductal cancer of the left breast (pT1b, G2, pN0, ER positive, PR positive, HER-2/neu negative) treated in July 2012 with breast-conserving surgery, adjuvant chemotherapy with 6 cycles of epirubicin and cyclophosphamide, adjuvant irradiation of the left breast with 50 Gray, and adjuvant endocrine therapy with an aromatase inhibitor...
April 24, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29689765/characterization-of-ct-hounsfield-units-for-3d-acquisition-trajectories-on-a-dedicated-breast-ct-system
#6
Jainil P Shah, Steve D Mann, Randolph L McKinley, Martin P Tornai
Hounsfield Units (HU) are used clinically in differentiating tissue types in a reconstructed CT image, and therefore the HU accuracy of a system is important, especially when using multiple sources, novel detector and non-traditional trajectories. Dedicated clinical breast CT (BCT) systems therefore should be similarly evaluated. In this study, uniform cylindrical phantoms filled with various uniform density fluids were used to characterize differences in HU values between simple circular and complex 3D (saddle) orbits...
April 18, 2018: Journal of X-ray Science and Technology
https://www.readbyqxmd.com/read/29689598/correlation-between-circulating-cell-free-pik3ca-tumor-dna-levels-and-treatment-response-in-patients-with-pik3ca-mutated-metastatic-breast-cancer
#7
Annette R Kodahl, Sidse Ehmsen, Niels Pallisgaard, Anne Marie B Jylling, Jeanette Dupont Jensen, Anne-Vibeke Laenkholm, Ann S Knoop, Henrik J Ditzel
Liquid biopsies focusing on the analysis of circulating cell-free tumor DNA (ctDNA) may have important clinical implications for personalized medicine, including early detection of cancer, therapeutic guidance and monitoring of recurrence. Mutations in the oncogene, PIK3CA, are frequently observed in breast cancer and have been suggested as a predictive biomarker for PI3K-selective inhibitor treatment. In this study, we analyzed the presence of PIK3CA mutations in formalin-fixed, paraffin-embedded, metastatic tissue and corresponding ctDNA from serum of patients with advanced breast cancer using a highly-sensitive, optimized droplet digital PCR (ddPCR) assay...
April 24, 2018: Molecular Oncology
https://www.readbyqxmd.com/read/29689480/the-need-to-be-all-inclusive-chest-ct-scans-should-include-imaged-breast-parenchyma
#8
EDITORIAL
Mary Salvatore, Laurie Margolies, Alexandra Bertolini, Ayushi Singh, David Yankelevitz, Claudia Henschke
The benefits of early diagnosis and treatment of breast cancer are well established. Thoracic CT which is performed with increased frequency for lung cancer screening can diagnose breast cancer earlier then might be possible clinically. The imaged and radiation exposed breasts must be included in their entirety on images which are reviewed by the radiologist. Because of concerns about how altering the field of view might affect image quality, we advocate for inclusion of the entire breast on the soft tissue series, which can be viewed on mediastinal window settings and expose the patient to no additional radiation...
April 19, 2018: Clinical Imaging
https://www.readbyqxmd.com/read/29688933/radiologic-aspects-of-the-diagnosis-of-pulmonary-embolism-in-pregnancy
#9
Benjamin S Harris, Katherine C Bishop, Jeffrey A Kuller
Pulmonary embolism in pregnancy is a leading cause of maternal mortality. The clinical presentation is often nonspecific, making imaging essential for accurate diagnosis. After reviewing the literature on the radiologic diagnosis of pulmonary embolism in pregnancy, we concluded that both computed tomography pulmonary angiography and lung perfusion scintigraphy are sensitive with high positive predictive values in the presence of high clinical suspicion, but lung perfusion scintigraphy is recommended given lower maternal breast exposure to ionizing radiation and lower fetal contrast exposure...
June 2018: Clinical Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29688834/reducing-body-image-related-distress-in-women-with-breast-cancer-using-a-structured-online-writing-exercise-results-from-the-my-changed-body-randomized-controlled-trial
#10
Kerry A Sherman, Astrid Przezdziecki, Jessica Alcorso, Christopher Jon Kilby, Elisabeth Elder, John Boyages, Louise Koelmeyer, Helen Mackie
Purpose Breast cancer treatment adverse effects result in one in three survivors experiencing body image-related distress (BID) that negatively impacts on a woman's ability to recover after cancer and into survivorship. My Changed Body (MyCB) is a Web-based psychological intervention to alleviate BID and improve body appreciation in survivors of breast cancer (BCSs) through a single-session, self-compassion focused writing activity. This randomized controlled trial evaluated the impact of MyCB on BID and body appreciation in BCSs...
April 24, 2018: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29688040/commentary
#11
Victoria Mango, Yolanda Bryce, Elizabeth Anne Morris, Elisabetta Gianotti, Katja Pinker
Screening mammography reduces breast cancer mortality in average-risk women. However, adverse consequences include false-positive findings possibly leading to benign breast biopsies and patient anxiety. There is also potential for overdiagnosis and overtreatment. Differences in how to balance benefits and harms have led to varying recommendations by the U.S. Preventive Services Task Force, the American Cancer Society, the National Comprehensive Cancer Network and the American College of Radiology/Society of Breast Imaging...
April 24, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29688026/incidental-pulmonary-embolism-in-oncology-patients-with-current-macroscopic-malignancy-incidence-in-different-tumour-type-and-impact-of-delayed-treatment-on-survival-outcome
#12
Maung Maung Myat Moe, Sridhar Redla
OBJECTIVES: To evaluate the incidence and outcome of incidental PE (iPE) in patients with current macroscopic malignancy and delayed anticoagulation due to late reporting of CT scan. METHODS: Reports of CT thorax with iv contrast done on oncology patients between 01.01.15 and 31.12.15 in two district general hospitals in UK were reviewed. Electronic patient records of iPE patients were reviewed for demographic and treatment information. RESULTS: 26 iPEs were reported in 1,604 scans (731 patients), incidence 1...
April 24, 2018: British Journal of Radiology
https://www.readbyqxmd.com/read/29687979/evaluating-the-association-between-artificial-light-at-night-exposure-and-breast-and-prostate-cancer-risk-in-spain-mcc-spain-study
#13
Ariadna Garcia-Saenz, Alejandro Sánchez de Miguel, Ana Espinosa, Antonia Valentin, Núria Aragonés, Javier Llorca, Pilar Amiano, Vicente Martín Sánchez, Marcela Guevara, Rocío Capelo, Adonina Tardón, Rosana Peiró-Perez, José Juan Jiménez-Moleón, Aina Roca-Barceló, Beatriz Pérez-Gómez, Trinidad Dierssen-Sotos, Tania Fernández-Villa, Conchi Moreno-Iribas, Victor Moreno, Javier García-Pérez, Gemma Castaño-Vinyals, Marina Pollán, Martin Aubé, Manolis Kogevinas
BACKGROUND: Night shift work, exposure to light at night (ALAN) and circadian disruption may increase the risk of hormone-dependent cancers. OBJECTIVES: We evaluated the association of exposure to ALAN during sleeping time with breast and prostate cancer in a population based multicase-control study (MCC-Spain), among subjects who had never worked at night. We evaluated chronotype, a characteristic that may relate to adaptation to light at night. METHODS: We enrolled 1,219 breast cancer cases, 1,385 female controls, 623 prostate cancer cases, and 879 male controls from 11 Spanish regions in 2008-2013...
April 23, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29687544/palpable-breast-abnormalities-in-women-under-age-40
#14
Michelle V Lee, Hillary L Shaw, Tingying Chi, Hilary A Brazeal, Susan O Holley, Catherine M Appleton
Although the prevalence of malignancy in average risk women under age 40 presenting with a palpable breast abnormality is low, the management of benign-appearing palpable abnormalities remains controversial. This study assesses the imaging evaluation, subsequent management, and outcomes of women under age 40 presenting with a palpable area of concern. This study also evaluates the costs, utility, and outcomes of BI-RADS 3 assessment in this patient population. A single institution retrospective case review from July 2010 through June 2013 identified women under age 40 presenting with a new palpable breast abnormality...
April 24, 2018: Breast Journal
https://www.readbyqxmd.com/read/29687537/incidence-and-outcomes-of-incidental-breast-lesions-detected-on-cross-sectional-imaging-examinations
#15
Eniola Falomo, Roberta M Strigel, Richard Bruce, Alejandro Munoz Del Rio, Catherine Adejumo, Frederick Kelcz
The aim of this study was to determine the frequency and outcomes of incidental breast lesions detected on nonbreast specific cross-sectional imaging examinations. A retrospective review of the medical records was performed to identify all patients without a known history of breast cancer, who had an incidentally discovered breast lesion detected on a nonbreast imaging examination performed at our institution between September 2008 and August 2012 for this IRB-approved, HIPAA compliant study. Outcomes of the incidental lesions were determined by follow-up with dedicated breast imaging (mammography, breast ultrasound, and/or breast MRI) or results of biopsy, if performed...
April 23, 2018: Breast Journal
https://www.readbyqxmd.com/read/29687535/management-of-intraductal-papilloma-without-atypia-of-the-breast-diagnosed-on-core-biopsy-size-and-sampling-matter
#16
Brittany Symbol, Andrew Ricci
Due to the potential for atypia (atypical ductal or lobular hyperplasia) or carcinoma (in situ or invasive) on excision, aggressive reflex surgical excision protocols following core biopsy diagnosis of papillary lesions of the breast (ie, intraductal papilloma) are commonplace. Concepts in risk stratification, including radiologic-pathologic correlation, are emerging in an effort to curb unnecessary surgeries. To this end, we examined all excised intraductal papillomas diagnosed at our institution from 2010-2015 (N = 336) and found an overall atypia rate of 20%...
April 23, 2018: Breast Journal
https://www.readbyqxmd.com/read/29687530/radiographically-guided-shave-margins-may-reduce-lumpectomy-re-excision-rates
#17
Kelsey E Larson, Priya Jadeja, Alison Marko, Veeraj Jadeja, Debra Pratt
Minimizing margin re-excision optimizes patient care by providing appropriate oncologic resection and reducing costs. This study aims to assess margin positivity rate in two groups: shave margin based on gross specimen (control group, CG) vs shave margin based on intraoperative imaging (radiographic group, RG). A total of 182 patients who underwent lumpectomy for stage O-III breast cancer at a single institution from January 2013 to January 2014 were evaluated. There was statistically significant decrease in margin re-excision rate with intraoperative mammography but not with ultrasound...
April 23, 2018: Breast Journal
https://www.readbyqxmd.com/read/29686118/pearls-oy-sters-the-critical-role-of-histopathology-in-diagnosing-cancer-associated-necrotizing-cns-vasculitis
#18
Joshua Sheehan, Jessica Tate, Ryan Mott, Carol Geer, Rachel Wolfe, Roy E Strowd, Amy Guzik
OBJECTIVE: To highlight the importance of a broad differential and histopathologic confirmation in patients with newly diagnosed cancer with brain lesions atypical for CNS metastasis. METHODS: We report 2 cases of biopsy-proven CNS vasculitis in patients undergoing treatment for a newly diagnosed nonmetastatic cancer. Comprehensive medical record review was performed to identify the clinical presentation, representative neuroimaging, histopathologic features, and response to treatment...
April 24, 2018: Neurology
https://www.readbyqxmd.com/read/29685400/comparing-the-performances-of-magnetic-resonance-imaging-size-vs-pharmacokinetic-parameters-to-predict-response-to-neoadjuvant-chemotherapy-and-survival-in-patients-with-breast-cancer
#19
Basak E Dogan, Qing Yuan, Roland Bassett, Inanc Guvenc, Edward F Jackson, Massimo Cristofanilli, Gary J Whitman
PURPOSE: To compare the value of dynamic contrast-enhanced magnetic resonance imaging-pharmacokinetic (PK) parameters vs tumor volume in predicting breast cancer neoadjuvant chemotherapy response (NACR) and patient survival. SUBJECTS AND METHODS: Sixty-six patients with locally advanced breast cancer who underwent breast MRI monitoring of NACR were retrospectively analyzed. We compared baseline transfer constant (Ktrans ), reflux rate contrast (kep ), and extracellular extravascular volume fraction (ve ) with the same parameters obtained at early postchemotherapy MRI, and examined model-independent changes in time-intensity curves (maximum slope, contrast enhancement ratio, and IAUC90)...
March 28, 2018: Current Problems in Diagnostic Radiology
https://www.readbyqxmd.com/read/29685346/patient-navigation-to-improve-cancer-screening-in-underserved-populations-reported-experiences-opportunities-and-challenges
#20
Chrishanae D Neal, Davis T Weaver, Tiana J Raphel, Anna P Lietz, Efren J Flores, Sanja Percac-Lima, Amy B Knudsen, Pari V Pandharipande
Our goal is to define patient navigation for an imaging audience, present a focused selection of published experiences with navigation programs for breast and colorectal cancer screening, and expose principal barriers to the success of such programs. Despite numerous advances in the early detection of cancers, many patients still present with advanced disease. A disproportionate number are low-income minority patients who experience worse health outcomes than their white or more financially stable counterparts...
April 20, 2018: Journal of the American College of Radiology: JACR
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