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https://www.readbyqxmd.com/read/29036752/breast-cancer-screening-updated-recommendations-of-the-brazilian-college-of-radiology-and-diagnostic-imaging-brazilian-breast-disease-society-and-brazilian-federation-of-gynecological-and-obstetrical-associations
#1
Linei Augusta Brolini Dellê Urban, Luciano Fernandes Chala, Selma di Pace Bauab, Marcela Brisighelli Schaefer, Radiá Pereira Dos Santos, Norma Medicis de Albuquerque Maranhão, Ana Lucia Kefalas, José Michel Kalaf, Carlos Alberto Pecci Ferreira, Ellyete de Oliveira Canella, João Emílio Peixoto, Heverton Leal Ernesto de Amorim, Helio Sebastião Amâncio de Camargo Junior
No abstract text is available yet for this article.
October 2017: Revista Brasileira de Ginecologia e Obstetrícia
https://www.readbyqxmd.com/read/29036067/analyzing-visual-search-observers-using-eye-tracking-data-for-digital-breast-tomosynthesis-images
#2
Zhengqiang Jiang, Mini Das, Howard C Gifford
Visual-search (VS) model observers have the potential to provide reliable predictions of human-observer performance in detection-localization tasks. The purpose of this work was to examine some characteristics of human gaze on breast images with the goal of informing the design of our VS observers. Using a helmet-mounted eye-tracking system, we recorded the movement of gaze from human observers as they searched for masses in sets of 2D digital breast tomosynthesis (DBT) images. The masses in this study were of a single profile...
June 1, 2017: Journal of the Optical Society of America. A, Optics, Image Science, and Vision
https://www.readbyqxmd.com/read/29035996/radioguided-occult-lesion-localization-technical-procedures-and-clinical-applications
#3
Gianpiero Manca, Sara Mazzarri, Domenico Rubello, Elisa Tardelli, Roberto C Delgado-Bolton, Francesco Giammarile, Manuela Roncella, Duccio Volterrani, Patrick M Colletti
PURPOSE: Regarding radioguided surgery, the concept of "radioguided occult lesion localization" (ROLL) is based on both preoperative interventional imaging and intraoperative radioguided detection of a clinically occult neoplastic lesion. METHODS: This methodology consists in the direct administration into the lesion of Tc-macroaggregated human albumin formed by relatively large particles retained at the injection site, which direct radioguided excisional biopsy...
October 13, 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29035873/multi-task-transfer-learning-deep-convolutional-neural-network-application-to-computer-aided-diagnosis-of-breast-cancer-on-mammograms
#4
Ravi K Samala, Heang-Ping Chan, Lubomir M Hadjiiski, Mark A Helvie, Kenny Cha, Caleb Richter
Transfer learning in deep convolutional neural networks (DCNNs) is an important step in its application to medical imaging tasks. We propose a multi-task transfer learning DCNN with the aims of translating the 'knowledge' learned from non-medical images to medical diagnostic tasks through supervised training and increasing the generalization capabilities of DCNNs by simultaneously learning auxiliary tasks. We studied this approach in an important application: classification of malignant and benign breast masses...
October 16, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/29033686/serendipitous-detection-of-extraosseous-metastases-on-bone-scintigraphy-utility-of-cross-sectional-and-correlative-imaging
#5
Jiwan Paudel, Harmandeep Singh, Ashwani Sood, Anish Bhattacharya, Bhagwant Rai Mittal
Whole body bone scintigraphy is most commonly used imaging modality to detect and assess the extent of osteoblastic osseous metastases in malignant conditions, though visceral metastases need additional imaging. The authors describe a case of 50-year-old postoperative breast cancer female where bone scintigraphy showed soft tissue uptake in thorax and hepatic region in addition to multiple skeletal metastases, indicating the involvement of three different organs by metastatic disease. The present case highlights that extraosseous tracer uptake in addition to abnormal osseous tracer uptake may raise the suspicion of widespread and visceral metastatic disease and warrant further evaluation in the form of cross-sectional and correlative imaging...
October 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29033679/incremental-value-of-single-photon-emission-computed-tomography-computed-tomography-for-characterization-of-skeletal-lesions-in-breast-cancer-patients
#6
Thanuja Mahaletchumy, Aini AbAziz
The incremental value of single-photon emission computed tomography-computed tomography (SPECT-CT) over planar bone scintigraphy and SPECT in detecting skeletal lesions in breast cancer patients and its effect on patient management is assessed in this study. This is a prospective study which was conducted over 1-year duration. Whole-body planar scintigraphy, SPECT, and SPECT-CT were performed in 85 breast cancer patients with total of 128 lesions. Correlative imaging and clinical follow-up was used as the reference standard...
October 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29033675/considering-the-relationship-between-quantitative-parameters-and-prognostic-factors-in-breast-cancer-can-mean-standardized-uptake-value-be-an-alternative-to-maximum-standardized-uptake-value
#7
Reyhan Köroğlu, İsmail Köksal, Fikri Selçuk Şimşek, Fatma Gezer, Ersoy Kekilli, Bülent Ünal
It was aimed to investigate the correlation between maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), and retention index (RI), which represents the quantitative evaluation of the uptake of (18)F-fluoro-2-deoxy-D-glucose ((18)F-FDG) used in positron emission tomography (PET) and clinicopathologic as well as biologic prognostic factors. Forty-one women with breast cancer who were histopathologically diagnosed were included in this study. Neoadjuvant chemotherapy was applied to all patients before PET/computed tomography (CT)...
October 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/29033147/apparent-diffusion-coefficient-value-to-evaluate-tumor-response-after-neoadjuvant-chemotherapy-in-patients-with-breast-cancer
#8
Yazmín Aseret Ramírez-Galván, Servando Cardona-Huerta, Guillermo Elizondo-Riojas, Neri Alejandro Álvarez-Villalobos
RATIONALE AND OBJECTIVES: This study explored tumor behavior in patients with breast cancer during neoadjuvant chemotherapy (NAC) by sequential measurements of tumor apparent diffusion coefficient (ADC) after each chemotherapy cycle. The aim was to determine if the tumor ADC is useful to differentiate complete pathological response (cPR) from partial pathological response (pPR) during NAC. MATERIALS AND METHODS: A total of 16 cases (in 14 patients) with diagnosis of breast cancer eligible to receive NAC were included...
October 12, 2017: Academic Radiology
https://www.readbyqxmd.com/read/29031230/astatine-211-labeled-anti-her2-5f7-single-domain-antibody-fragment-conjugates-radiolabeling-and-preliminary-evaluation
#9
Jaeyeon Choi, Ganesan Vaidyanathan, Eftychia Koumarianou, Choong Mo Kang, Michael R Zalutsky
INTRODUCTION: Derived from heavy chain only camelid antibodies, ~15-kDa single-domain antibody fragments (sdAbs) are an attractive platform for developing molecularly specific imaging probes and targeted radiotherapeutics. The rapid tumor accumulation and normal tissue clearance of sdAbs might be ideal for use with (211)At, a 7.2-h half-life α-emitter, if appropriate labeling chemistry can be devised to trap (211)At in cancer cells after sdAb binding. This study evaluated two reagents, [(211)At]SAGMB and iso-[(211)At]SAGMB, for this purpose...
September 19, 2017: Nuclear Medicine and Biology
https://www.readbyqxmd.com/read/29031099/shear-wave-elastography-for-characterization-of-breast-lesions-shearlet-transform-and-local-binary-pattern-histogram-techniques
#10
U Rajendra Acharya, Wei Lin Ng, Kartini Rahmat, Vidya K Sudarshan, Joel E W Koh, Jen Hong Tan, Yuki Hagiwara, Arkadiusz Gertych, Farhana Fadzli, Chai Hong Yeong, Kwan Hoong Ng
Shear wave elastography (SWE) examination using ultrasound elastography (USE) is a popular imaging procedure for obtaining elasticity information of breast lesions. Elasticity parameters obtained through SWE can be used as biomarkers that can distinguish malignant breast lesions from benign ones. Furthermore, the elasticity parameters extracted from SWE can speed up the diagnosis and possibly reduce human errors. In this paper, Shearlet transform and local binary pattern histograms (LBPH) are proposed as an original algorithm to differentiate malignant and benign breast lesions...
October 2, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29030785/usefulness-of-abbreviated-breast-mri-screening-for-women-with-a-history-of-breast-cancer-surgery
#11
Bo Hwa Choi, Nami Choi, Mi Young Kim, Jung-Hyun Yang, Young Bum Yoo, Hae Kyoung Jung
PURPOSE: We investigated the usefulness of abbreviated breast MRI (AB-MRI), including fat-suppressed T2-weighted imaging, pre- and postcontrast image acquisition, and subtracted maximum-intensity projection imaging, for the screening of women with a history of breast cancer surgery. METHODS: Between October 2014 and March 2016, a total of 799 AB-MRI examinations were performed for 725 women with a history of breast cancer surgery. The image acquisition time was 8...
October 13, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29030460/hmg-coa-reductase-inhibition-delays-dna-repair-and-promotes-senescence-after-tumor-irradiation
#12
Elena V Efimova, Natalia Ricco, Edwardine Labay, Helena J Mauceri, Amy C Flor, Aishwarya Ramamurthy, Harold G Sutton, Ralph R Weichselbaum, Stephen J Kron
Despite significant advances in combinations of radiotherapy and chemotherapy, altered fractionation schedules and image-guided radiotherapy, many cancer patients fail to benefit from radiation. A prevailing hypothesis is that targeting repair of DNA double strand breaks (DSBs) can enhance radiation effects in the tumor and overcome therapeutic resistance without incurring off-target toxicities. Unrepaired DSBs can block cancer cell proliferation, promote cancer cell death and induce cellular senescence. Given the slow progress to date translating novel DSB repair inhibitors as radiosensitizers, we have explored drug repurposing, a proven route to improving speed, costs and success rates of drug development...
October 13, 2017: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/29029766/diagnostic-performance-of-gadofosveset-enhanced-axillary-mri-for-nodal-re-staging-in-breast-cancer-patients-results-of-a-validation-study
#13
T J A van Nijnatten, R-J Schipper, M B I Lobbes, L M van Roozendaal, S Vöö, M Moossdorff, M-L Paiman, B de Vries, K B M I Keymeulen, J E Wildberger, M L Smidt, R G H Beets-Tan
AIM: To evaluate diagnostic performance of gadofosveset (GDF)-enhanced magnetic resonance imaging (MRI) in addition to T2-weighted (T2W) MRI for nodal (re)staging in newly diagnosed breast cancer patients. MATERIALS AND METHODS: Ninety patients underwent axillary T2W- and GDF-MRI. Two radiologists independently scored each lymph node; first on T2W-MRI, subsequently adjusting their score on GDF-MRI. Diagnostic performance parameters were calculated on node-by-node and patient-by-patient validation with histopathology as the reference standard...
October 10, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/29029470/real-time-in-vivo-imaging-of-metastatic-bone-tumors-with-a-targeted-near-infrared-fluorophore
#14
Wonbong Lim, HongMoon Sohn, Youngjong Ko, Mineon Park, Bora Kim, Danbi Jo, Jin Seok Jung, Dae Hyeok Yang, Jangho Kim, Ok Joon Kim, Donghwi Kim, Young Lae Moon, Jung-Joon Min, Hoon Hyun
Tumors of the prostate or breast are particularly likely to metastasize to the bone, and early diagnosis of metastatic bone tumors is important for designing an effective treatment strategy. Imaging modalities for the detection of bone metastasis are limited, and radiation-based techniques are commonly used. Here, we investigated the efficacy of selective near-infrared (NIR) fluorescence detection of metastatic bone tumors and its role in the detection of bone metastasis in prostate and breast cancer cell lines and in a xenograft mouse model...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29028311/radiolabeled-antibody-conjugated-manganese-oxide-nanoparticles-for-tumor-vasculature-targeted-positron-emission-tomography-and-magnetic-resonance-imaging
#15
Yonghua Zhan, Sixiang Shi, Emily B Ehlerding, Stephen A Graves, Shreya Goel, Jonathan W Engle, Jimin Liang, Jie Tian, Weibo Cai
Manganese oxide nanoparticles (Mn3O4 NPs) have attracted a great deal of attention in the field of biomedical imaging because of their ability to create an enhanced imaging signal in MRI as novel potent T1 contrast agents. In this study, we present tumor vasculature-targeted imaging in mice using Mn3O4 NPs through conjugation to the anti-CD105 antibody TRC105 and radionuclide copper-64 ((64)Cu, t1/2: 12.7 h). The Mn3O4 conjugated NPs, (64)Cu-NOTA-Mn3O4@PEG-TRC105, exhibited sufficient stability in vitro and in vivo...
October 13, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29028087/axillary-ectopic-lobular-carcinoma-of-breast-two-rare-case-reports
#16
A Conversi, M L Meggiorini, P Fino, G Soda, N Scuderi, M G Onesti
OBJECTIVE: The presence of ectopic or supernumerary breast tissue is a rare event, related to a not complete regression of breast tissue along the milk line. Primary ectopic breast cancer of the axilla can create many difficulties in differential diagnosis with subsequent delayed specific treatments. The incidence of ectopic breast tissue is 0.2-6%, and the axilla is the most common site involved. In this tissue, the same physiologic and pathologic changes as seen in ectopic breast tissue may occur, including carcinoma formation...
September 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/29028040/ex-vivo-validation-of-photo-magnetic-imaging
#17
Alex Luk, Farouk Nouizi, Hakan Erkol, Mehmet B Unlu, Gultekin Gulsen
We recently introduced a new high-resolution diffuse optical imaging technique termed photo-magnetic imaging (PMI), which utilizes magnetic resonance thermometry (MRT) to monitor the 3D temperature distribution induced in a medium illuminated with a near-infrared light. The spatiotemporal temperature distribution due to light absorption can be accurately estimated using a combined photon propagation and heat diffusion model. High-resolution optical absorption images are then obtained by iteratively minimizing the error between the measured and modeled temperature distributions...
October 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/29027318/imaging-and-pathology-features-to-predict-axillary-tumor-load-in-breast-cancer
#18
Pau Nicolau, Rocio Gamero, Ana Rodríguez-Arana, Francisco Plancarte, Rodrigo Alcántara, Ramon Carreras, Dolors Sabadell, Mar Vernet-Tomas
AIM: We investigated if imaging and pathology features could help to identify a high axillary tumor burden (ATB) in breast cancer patients, in order to individualize decisions on axillary lymph node (ALN) dissection (ALND). METHODS: We retrospectively analyzed patients primarily treated with surgery in our unit between 2011 and 2014. We divided the patients in two groups: low ATB (LATB) if ≤ 2 ALN were infiltrated and high ATB (HATB) if > 2 ALN were infiltrated...
October 13, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29027063/inflammatory-myofibroblastic-tumors-of-the-breast-with-simultaneous-intracranial-lung-and-pancreas-involvement-ultrasonographic-findings-and-a-review-of-the-literature
#19
Mari Inoue, Tomoyuki Ohta, Hisashi Shioya, Shun Sato, Hiroyuki Takahashi, Norio Nakata, Chiaki Taniguchi, Megumi Hirano, Makiko Nishioka, Hironori Yamakawa
We encountered a case of inflammatory myofibroblastic tumor (IMT) of the breast with simultaneous intracranial, lung, and pancreas involvement. Here, we present the clinical imaging results and report the significance of sonographic findings of breast IMT along with a review of the literature. A 16-year-old girl with a history of subarachnoidal hemorrhage was admitted to our hospital due to tonic-clonic seizure. Computed tomography (CT) and magnetic resonance imaging (MRI) showed multiple intracranial, lung, and pancreas mass lesions and a solitary mass lesion in the right breast...
October 12, 2017: Journal of Medical Ultrasonics
https://www.readbyqxmd.com/read/29026824/textured-breast-implants-a-closer-look-at-the-surface-debris-under-the-microscope
#20
Leland H Webb, Victoria L Aime, Annie Do, Kenneth Mossman, Raman C Mahabir
BACKGROUND: Texturing of breast implants is done to decrease the risk of associated complications. Each manufacturer utilizes unique and at times proprietary techniques to texture the surface of their implants. Little is known about the integrity of this surface structure texturing or the propensity for the surfaces to shed particulate matter. This study aimed to determine the extent of surface particulate shedding from 3 textured implants approved by the US Food and Drug Administration (FDA), which are manufactured by Allergan, Mentor, and Sientra...
August 2017: Plastic Surgery
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