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https://www.readbyqxmd.com/read/28654974/the-role-of-patient-engagement-in-addressing-parents-perceptions-about-immunizations
#1
Mary C Politi, Katherine M Jones, Sydney E Philpott
No abstract text is available yet for this article.
June 22, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28654874/aquatic-toxicity-of-ivermectin-in-cattle-dung-assessed-using-microcosms
#2
Leticia M Mesa, I Lindt, L Negro, M F Gutierrez, G Mayora, L Montalto, M Ballent, A Lifschitz
Ivermectin (IVM) is a parasiticide widely used for livestock. It is a semisynthetic derivative of avermectin, a macrocyclic lactone produced by Streptomyces avermitilis. This drug is only partly metabolized by livestock; considerable amounts of parent drug are excreted mostly via feces. To simulate exposure of aquatic invertebrates and macrophytes to direct excretion of cattle dung into surface waters, a microcosm experiment with IVM spiked in cattle dung was conducted. The objectives of this study were to characterize accumulation of IVM in water, sediment+dung, roots of the floating fern Salvinia and the zooplankton Ceriodaphnia dubia, the amphipod Hyalella and the apple snail Pomacea; to determine the effect of this drug spiked in cattle dung on life-history traits of these invertebrates; and to evaluate the influence of IVM on aquatic nutrient cycling...
June 24, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28654845/alcohol-related-cognitions-in-children-aged-2-10-and-how-they-are-shaped-by-parental-alcohol-use-a-systematic-review
#3
REVIEW
Carmen Voogt, Miriam Beusink, Marloes Kleinjan, Roy Otten, Rutger Engels, Koen Smit, Emmanuel Kuntsche
BACKGROUND: This systematic review aims to summarize the evidence of the impact of parental alcohol use on the acquisition of children's alcohol-related cognitions (alcohol-related knowledge, alcohol-related norms, alcohol expectancies) in the developmental period from age two to ten. METHODS: A computer-assisted systematic literature search was performed in PubMed, PsychINFO, ERIC, and EMBASE. Overall, 20 out of the 3406 unique articles identified in the first screening were included...
June 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28654843/naturalistic-assessment-of-the-learner-license-period
#4
J P Ehsani, S G Klauer, C Zhu, P Gershon, T A Dingus, B G Simons-Morton
The purpose of this study was to describe the characteristics and progression of practice driving during the learner license period in a sample of teenagers. During the first and last 10h of practice driving, we examined (1) the amount, variety and complexity of conditions of practice; (2) the nature of parental instruction; and (3) errors that teens made while driving. Data were collected from 90 teens and 131 parents living in Virginia, USA, using in-vehicle cameras, audio recorders, GPS and trip recorders...
June 24, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28654821/table%C3%A2-talk-how-mothers-and-adolescents-across-socioeconomic-status-discuss-food
#5
Priya Fielding-Singh, Jennifer Wang
This article reports findings from a qualitative study of food practices among families of differing socioeconomic circumstances. Using in-depth interviews from sixty-two families in the San Francisco Bay Area in 2015-2016, we find socioeconomic differences in how mothers and adolescents talk about food. Across SES, mothers and adolescents engage in discussions about healthy eating. However, these conversations are more commonplace and embedded within high-SES family life than among low-SES families. Beyond conversations about 1) healthy eating, the topics of 2) food quality and 3) price are discussed to varying degrees across SES...
June 15, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28654691/whole-gene-analysis-of-two-groups-of-hepatitis-b-virus-c-d-inter-genotype-recombinant-strains-isolated-in-tibet-china
#6
Tiezhu Liu, Fuzhen Wang, Shuang Zhang, Feng Wang, Qingling Meng, Guomin Zhang, Fuqiang Cui, Dorji Dunzhu, Wenjiao Yin, Shengli Bi, Liping Shen
Tibet is a highly hepatitis B virus (HBV) endemic area. Two types of C/D recombinant HBV are commonly isolated in Tibet and have been previously described. In an effort to better understand the molecular characteristic of these C/D recombinant strains from Tibet, we undertook a multistage random sampling project to collect HBsAg positive samples. Molecular epidemiological and bio-informational technologies were used to analyze the characteristics of the sequences found in this study. There were 60 samples enrolled in the survey, and we obtained 19 whole-genome sequences...
2017: PloS One
https://www.readbyqxmd.com/read/28654647/ancient-female-philopatry-asymmetric-male-gene-flow-and-synchronous-population-expansion-support-the-influence-of-climatic-oscillations-on-the-evolution-of-south-american-sea-lion-otaria-flavescens
#7
Larissa Rosa de Oliveira, Marcelo C M Gehara, Lúcia D Fraga, Fernando Lopes, Juan Ignacio Túnez, Marcelo H Cassini, Patricia Majluf, Susana Cárdenas-Alayza, Héctor J Pavés, Enrique Alberto Crespo, Nestor García, Rocío Loizaga de Castro, A Rus Hoelzel, Maritza Sepúlveda, Carlos Olavarría, Victor Hugo Valiati, Renato Quiñones, Maria Jose Pérez-Alvarez, Paulo Henrique Ott, Sandro L Bonatto
The South American sea lion (Otaria flavescens) is widely distributed along the southern Atlantic and Pacific coasts of South America with a history of significant commercial exploitation. We aimed to evaluate the population genetic structure and the evolutionary history of South American sea lion along its distribution by analyses of mitochondrial DNA (mtDNA) and 10 nuclear microsatellites loci. We analyzed 147 sequences of mtDNA control region and genotyped 111 individuals of South American sea lion for 10 microsatellite loci, representing six populations (Peru, Northern Chile, Southern Chile, Uruguay (Brazil), Argentina and Falkland (Malvinas) Islands) and covering the entire distribution of the species...
2017: PloS One
https://www.readbyqxmd.com/read/28654610/what-s-new-in-syndromic-craniosynostosis-surgery
#8
Jesse A Taylor, Scott P Bartlett
LEARNING OBJECTIVES: After studying this article, the participant should be able to: 1. Understand the role of prenatal screening and counseling of parents of unborn children with syndromic craniosynostosis. 2. Recognize the genetic abnormalities, craniofacial phenotype, associated anomalies, and challenges associated with each of the five major forms of syndromic craniosynostosis. 3. Identify the pros and cons associated with timing and types of cranial vault remodeling techniques in this patient population...
July 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28654555/the-experience-of-pain-dismissal-in-adolescence
#9
Ellen K Defenderfer, Kate Bauer, Eva Igler, Julia A Uihlein, W Hobart Davies
CONTEXT: Pain in adolescence has psychosocial effects lasting into adulthood, including increased likelihood of pain in adulthood and higher rates of depression and anxiety. Many adolescents with chronic pain describe skepticism of pain reports, but this has not yet been evaluated in a sample of typically developing adolescents. OBJECTIVE: The current study sought to describe the experience of perceived pain dismissal during adolescence in a community sample. METHOD: Nearly two-thousand (1931) emerging adults were recruited from the community and answered open-ended questions regarding whether they had experienced dismissal of their pain in adolescence, who dismissed their pain, characteristics of the dismisser, and what that experience was like...
June 16, 2017: Clinical Journal of Pain
https://www.readbyqxmd.com/read/28654504/how-accurately-do-both-parents-and-health-professionals-assess-overweight-in-children
#10
Ickpyo Hong, Cynthia Brown Dodds, Patty Coker-Bolt, Annie N Simpson, Craig A Velozo
BACKGROUND: An accurate perception of weight status is important to prevent childhood obesity. OBJECTIVE: We investigated whether parents and health professionals accurately identify children's weight status. METHODS: On the 2012 National Health and Nutrition Examination Survey: National Youth Fitness Survey, parents and health professionals rated the same child's weight status as overweight or healthy. The sensitivity and specificity of their answers were computed by comparing parents' and health professionals' ratings to the age growth chart from the US Centers for Disease Control and Prevention...
July 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28654503/effectiveness-of-functional-power-training-on-walking-ability-in-young-children-with-cerebral-palsy-study-protocol-of-a-double-baseline-trial
#11
Liesbeth F van Vulpen, Sonja de Groot, Eugene A A Rameckers, Jules G Becher, Annet J Dallmeijer
PURPOSE: To evaluate the effect of functional high-velocity resistance (power) training to improve walking ability of young children with cerebral palsy. METHODS: Twenty-two children with bi- or unilateral spastic cerebral palsy, Gross Motor Function Classification System levels I and II, aged 4 to 10 years will be recruited. A double-baseline design will be used to compare a 14-week functional power training (3 times a week) program with a 14-week usual care period and a 14-week follow-up period...
July 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28654490/a-home-based-body-weight-supported-treadmill-program-for-children-with-cerebral-palsy-a-pilot-study
#12
Allie Visser, Marci Westman, Sango Otieno, Lisa Kenyon
PURPOSE: The purpose of this pilot study was to explore the effect and feasibility of a home-based body weight-supported treadmill training (BWSTT) program on walking capacity and functional mobility in children with cerebral palsy (CP). METHODS: A within-subjects, repeated-measures design was used. Ten children with CP ages 6 to 16 years participated in pre- and postintervention testing sessions, an initial home training session, and a 12-week home-based BWSTT program conducted 3 to 4 times per week by a parent or caregiver for up to 20 minutes each session...
July 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28654480/overweight-and-obesity-in-children-more-than-just-the-kilos
#13
Edgar van Mil, Arianne Struik
A new model of diagnostics and treatment for overweight in children is used for implementation of a new approach toward childhood obesity. Although based in a hospital setting, it is part of a cure and care network with other professionals. By psycho-education about the body at a 6-year-old level, parents and children become informed and competent partners. This knowledge increases their autonomy and ability to make choices. Collaboration with the family's support group or network reduces isolation and increases the feeling of being connected and supported...
July 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28654416/the-evaluation-of-a-personal-narrative-language-intervention-for-school-age-children-with-down-syndrome
#14
Lizbeth Finestack, Katy H O'Brien, Jolene Hyppa-Martin, Kristen A Lyrek
The purpose of this study was to evaluate the feasibility of an intervention focused on improving personal narrative skills of school-age children with Down syndrome (DS) using an approach involving visual supports. Four females with DS, ages 10 through 15 years, participated in this multiple baseline across participants single-subject experimental design study. Participants completed 18 intervention sessions that targeted personal narrative goals. Parents completed a survey regarding their perspectives of the intervention...
July 2017: American Journal on Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/28654411/a-multi-method-investigation-of-pragmatic-development-in-individuals-with-down-syndrome
#15
Michelle Lee, Lauren Bush, Gary E Martin, Jamie Barstein, Nell Maltman, Jessica Klusek, Molly Losh
This longitudinal study examined pragmatic language in boys and girls with Down syndrome (DS) at up to three time points, using parent report, standardized and direct assessments. We also explored relationships among theory of mind, executive function, nonverbal mental age, receptive and expressive vocabulary, grammatical complexity, and pragmatic competence. Controlling for cognitive and language abilities, children with DS demonstrated greater difficulty than younger typically developing controls on parent report and standardized assessments, but only girls with DS differed on direct assessments...
July 2017: American Journal on Intellectual and Developmental Disabilities
https://www.readbyqxmd.com/read/28654297/eriodictyol-not-its-glucuronide-metabolites-attenuates-acetaminophen-induced-hepatotoxicity
#16
Ling Ye, Zhaoyu Wang, Yao Lan, Minghao Chen, Cailing Wen, Yanxian Hu, Zhong Qiu Liu
Acetaminophen (APAP) is one of the most commonly used oral analgesics and antipyretics, but hepatotoxicity including liver failure may occur after overdose. The therapeutic options for treating APAP hepatotoxicity are limited. Eriodictyol, a dietary flavonoid with anti-inflammatory and antioxidant properties, was used here to determine its protective effects against APAP-induced hepatotoxicity in mice. Various administration routes and pharmacokinetics-pharmacodynamics (PK-PD) analyses were used to determine these effects...
June 27, 2017: Molecular Pharmaceutics
https://www.readbyqxmd.com/read/28654273/luminescent-dinuclear-ruthenium-terpyridine-complexes-with-a-bis-phenylbenzimidazole-spacer
#17
Debiprasad Mondal, Sourav Biswas, Animesh Paul, Sujoy Baitalik
A conjugated bis-terpyridine bridging ligand, 2-(4-(2,6-di(pyridin-2-yl)pyridin-4-yl)phenyl)-6-(2-(4-(2,6-di(pyridin-2-yl)pyridin-4-yl)phenyl)-1H-benzo[d]imidazol-6-yl)-1H-benzo[d] imidazole (tpy-BPhBzimH2-tpy), was designed in this work by covalent coupling of 3,3'-diaminobenzidine and two 4'-(p-formylphenyl)-2,2':6',2″-terpyridine units to synthesize a new series of bimetallic Ru(II)-terpyridine light-harvesting complexes. Photophysical and electrochemical properties were modulated by the variation of the terminal ligands in the complexes...
June 27, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28653965/factors-influencing-the-underreporting-of-concussion-in-sports-a-qualitative-study-of-minor-hockey-participants
#18
Michael D Cusimano, Jane Topolovec-Vranic, Stanley Zhang, Sarah J Mullen, Mattew Wong, Gabriela Ilie
OBJECTIVE: The present study is to identify factors contributing to underreporting of concussion in adolescent athletes. DESIGN: Qualitative interviews. SETTING: Participants were interviewed in an office environment. PARTICIPANTS: Interviews were conducted with 31 minor hockey players, 10 parents, 6 coaches, 4 trainers, 2 managers, and one game official. Players were 13 to 15 year old. With selective sampling, an inductive approach of analyzing the interviews was undertaken and themes were identified and analyzed...
July 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/28653847/glucuronides-as-potential-anionic-substrates-of-human-cytochrome-p450-2c8-cyp2c8
#19
Yong Ma, Yue Fu, S Cyrus Khojasteh, Deepak Dalvie, Donglu Zhang
Glucuronidation is in general considered as a terminal metabolic step that leads to direct elimination of drugs and generally abolishes their biological activity. However, there is growing evidence to suggest that glucuronides can be ligands of human CYP2C8, making CYP2C8 distinct from the other CYP isoforms. Several classes of glucuronide conjugates, which include acyl glucuronides, ether glucuronides, N-glucuronides, and carbamoyl glucuronides, have been shown to be substrates or time-dependent inhibitors of CYP2C8...
June 27, 2017: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28653820/u-s-child-safety-seat-laws-are-they-effective-and-who-complies
#20
Lauren E Jones, Nicolas R Ziebarth
This paper assesses the effectiveness of child safety seat laws in the United States. Over the past 35 years, these laws have steadily increased mandatory child safety seat restraint ages. We exploit state-year level variation in the age until which children are required to ride in child safety seats to estimate triple difference models using Fatality Analysis Reporting System (FARS) data from 1975 to 2011. Our findings show that increasing the age thresholds is effective in increasing the actual age of children in safety seats...
2017: Journal of Policy Analysis and Management
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