Jie Yang, Zhenwei Zhou, Xiaolei Ding, Rong He, Ailin Li, Yuchi Wei, Mingyue Wang, Zeyu Peng, Zhanliang Jiang, Daqing Zhao, Xiangyan Li, Xiangyang Leng, Haisi Dong
BACKGROUND: Osteoarthritis (OA) is characterized by degeneration of articular cartilage, leading to joint pain and dysfunction. Gubi Zhitong formula (GBZTF), a traditional Chinese medicine formula, has been used in the clinical treatment of OA for decades, demonstrating definite efficacy. However, its mechanism of action remains unclear, hindering its further application. METHODS: The ingredients of GBZTF were analyzed and performed with liquid chromatography-mass spectrometry (LC-MS)...
January 11, 2024: Phytomedicine