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Sivasankaran Sivasubramonian, Arun Gopalakrishnan, Bijulal Sasidharan, Ajitkumar Valaparambil
Transient elevation of LV diastolic pressure above LA pressure can occur in severe aortic regurgitation in the diastasis phase. Mitral E wave reversal in such a situation could serve as non-invasive evidence of elevated left ventricular diastolic pressures, thereby guiding therapeutic decision making.
March 2018: Journal of Invasive Cardiology
Thomas A Treibel, Rebecca Kozor, Rebecca Schofield, Giulia Benedetti, Marianna Fontana, Anish N Bhuva, Amir Sheikh, Begoña López, Arantxa González, Charlotte Manisty, Guy Lloyd, Peter Kellman, Javier Díez, James C Moon
BACKGROUND: Left ventricular (LV) hypertrophy, a key process in human cardiac disease, results from cellular (hypertrophy) and extracellular matrix expansion (interstitial fibrosis). OBJECTIVES: This study sought to investigate whether human myocardial interstitial fibrosis in aortic stenosis (AS) is plastic and can regress. METHODS: Patients with symptomatic, severe AS (n = 181; aortic valve area index 0.4 ± 0.1 cm2 /m2 ) were assessed pre-aortic valve replacement (AVR) by echocardiography (AS severity, diastology), cardiovascular magnetic resonance (CMR) (for volumes, function, and focal or diffuse fibrosis), biomarkers (N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T), and the 6-min walk test...
February 27, 2018: Journal of the American College of Cardiology
Pablo Sanchez, Jordan J Lancaster, Kyle Weigand, Saffie-Alrahman Ezz-Eldin Mohran, Steven Goldman, Elizabeth Juneman
OBJECTIVE: For chronic heart failure (CHF), more emphasis has been placed on evaluation of systolic as opposed to diastolic function. Within the study of diastology, measurements of left ventricular (LV) longitudinal myocardial relaxation have the most validation. Anterior wall radial myocardial tissue relaxation velocities along with mitral valve inflow (MVI) patterns are applicable diastolic parameters in the differentiation between moderate and severe disease in the ischemic rat model of CHF...
October 2017: Journal of Cardiac Failure
Siddhartha S Angadi, Catherine L Jarrett, Moustafa Sherif, Glenn A Gaesser, Farouk Mookadam
AIMS: High-intensity interval training (HIIT) improves peak oxygen uptake and left ventricular diastology in patients with heart failure with preserved ejection fraction (HFpEF). However, its effects on myocardial strain in HFpEF remain unknown. We explored the effects of HIIT and moderate-intensity aerobic continuous training (MI-ACT) on left and right ventricular strain parameters in patients with HFpEF. Furthermore, we explored their relationship with peak oxygen uptake (VO2peak )...
August 2017: ESC Heart Failure
(no author information available yet)
No abstract text is available yet for this article.
December 1, 2016: European Heart Journal Cardiovascular Imaging
Allan L Klein, Natalie M Ho
No abstract text is available yet for this article.
December 2017: JACC. Cardiovascular Imaging
Taeha Ryu, Seok-Young Song
Anesthesiologists frequently see asymptomatic patients with diastolic dysfunction or heart failure for various surgeries. These patients typically show normal systolic function but abnormal diastolic parameters in their preoperative echocardiographic evaluations. The symptoms that are sometimes seen are similar to those of chronic obstructive pulmonary disease. Patients with diastolic dysfunction, and even with diastolic heart failure, have the potential to develop a hypertensive crisis or pulmonary congestion...
February 2017: Korean Journal of Anesthesiology
Arindam Choudhury, Rohan Magoon, Vishwas Malik, Poonam Malhotra Kapoor, S Ramakrishnan
Diastolic dysfunction is common in cardiac disease and an important finding independent of systolic function as it contributes to the signs and symptoms of heart failure. Tissue Doppler mitral early diastolic velocity (Ea) combined with peak transmitral early diastolic velocity (E) to obtain E/Ea ratio provides an estimate of the left ventricular (LV) filling pressure. However, E/Ea has a significant gray zone and less reliable in patients with preserved ejection fraction (>50%). Two-dimensional echocardiographic speckle tracking measure myocardial strain and strain rate (Sr) avoiding the Doppler-associated angulation errors and tethering artifacts...
January 2017: Annals of Cardiac Anaesthesia
Candice Morrissey
Diastolic dysfunction ranging from impaired relaxation of the left ventricle to heart failure with preserved ejection fraction (HFpEF) is a common finding in the cardiac surgery population. It is important for the peri-operative echocardiographer to have a developed understanding of the pathophysiology of diastolic dysfunction and the echocardiographic features that determine where on the spectrum of diastolic function and dysfunction a patient lies.
October 2016: Annals of Cardiac Anaesthesia
Takashi Oki, Hirokazu Miyoshi, Yoshifumi Oishi, Yukio Mizuguchi, Arata Iuchi, Hirotsugu Yamada, Satoshi Nakatani
Diastology is a study to treat diastole of the heart. Transmitral flow and pulmonary venous flow velocities recorded by pulsed Doppler echocardiography provide more important information about left ventricular (LV) diastolic dysfunction [left atrial (LA)-LV coupling] than cardiac catheterization in clinical practice; however, these waveforms are influenced by loading conditions, particularly preload. The early diastolic mitral annular and LV wall motion indices measured by tissue Doppler echocardiography can evaluate LV relaxation abnormality and filling pressure by being relatively preload independent...
September 2016: Journal of Echocardiography
(no author information available yet)
No abstract text is available yet for this article.
August 2016: Journal of the American Society of Echocardiography
Justin T Tretter, Mark K Friedberg, Rachel M Wald, Doff B McElhinney
Transcatheter pulmonary valve replacement (TPVR) is an important treatment option in repaired tetralogy of Fallot (TOF) and right ventricular outflow tract (RVOT) dysfunction. Indications for timing of TPVR are extrapolated from surgical pulmonary valve replacement guidelines, which are themselves controversial as published evidence is scarce and expert opinion therefore prevails. We review current indications for PVR following TOF repair, focusing on those for TPVR specifically, and discuss anatomical and functional considerations as these pertain to determination of candidacy for TPVR...
October 15, 2016: International Journal of Cardiology
Zoran B Popović, Paul C Cremer
No abstract text is available yet for this article.
May 2016: JACC. Cardiovascular Imaging
Brett W Sperry, Michael N Vranian, Rory Hachamovitch, Hariom Joshi, Asad Ikram, Dermot Phelan, Mazen Hanna
BACKGROUND: Light chain (AL) and transthyretin (ATTR) amyloidosis have a similar effect on myocardial function but very different disease trajectories and survival. However, limited data are available evaluating subtype-specific predictors of outcomes in a large contemporary cohort. METHODS AND RESULTS: We retrospectively investigated 360 patients at the time of initial diagnosis of cardiac amyloidosis (191 AL and 169 ATTR) from 2002 to 2014. Clinical, laboratory, electrical, and morphologic covariates were evaluated based upon amyloid subtype...
March 24, 2016: Journal of the American Heart Association
Karsten E Schober, Valérie Chetboul
Left ventricular (LV) diastolic dysfunction is highly prevalent in cats and is a functional hallmark of feline cardiomyopathy. The majority of cats with hypertrophic, restrictive, and dilated cardiomyopathy have echocardiographic evidence of abnormal LV filling, even during the occult (preclinical) phase. Moderate and severe diastolic dysfunction is an indicator of advanced myocardial disease, is associated with clinical signs including exercise intolerance and congestive heart failure, affects outcome, and influences therapeutic decisions...
December 2015: Journal of Veterinary Cardiology: the Official Journal of the European Society of Veterinary Cardiology
Robert R Ehrman, Frances M Russell, Asimul H Ansari, Bosko Margeta, Julie M Clary, Errick Christian, Karen S Cosby, John Bailitz
OBJECTIVES: The goal of this study was to determine if emergency physicians (EPs) can correctly perform a bedside diastology examination (DE) and correctly grade the level of diastolic function with minimal additional training in echocardiography beyond what is learned in residency. We hypothesize that EPs will be accurate at detecting and grading diastolic dysfunction (DD) when compared to a criterion standard interpretation by a cardiologist. METHODS: We conducted a prospective, observational study on a convenience sample of adult patients who presented to an urban emergency department with a chief concern of dyspnea...
September 2015: American Journal of Emergency Medicine
Antonio José Lagoeiro Jorge, Maria Luiza Garcia Rosa, Mario Luiz Ribeiro, Luiz Claudio Maluhy Fernandes, Monica Di Calafiori Freire, Dayse Silva Correia, Patrick Duarte Teixeira, Evandro Tinoco Mesquita
BACKGROUND: Heart failure with preserved ejection fraction (HFPEF) is the most common form of heart failure (HF), its diagnosis being a challenge to the outpatient clinic practice. OBJECTIVE: To describe and compare two strategies derived from algorithms of the European Society of Cardiology Diastology Guidelines for the diagnosis of HFPEF. METHODS: Cross-sectional study with 166 consecutive ambulatory patients (67.9±11.7 years; 72% of women)...
September 2014: Arquivos Brasileiros de Cardiologia
Nathan W Brunner, Mehdi Skhiri, Olga Fortenko, Andrew Hsi, Francois Haddad, Nayer Khazeni, Roham T Zamanian
BACKGROUND: Insulin resistance (IR) is an independent prognostic marker in pulmonary arterial hypertension (PAH), although the mechanism by which it engenders risk is unknown. We prospectively investigated the clinical, laboratory, hemodynamic, and echocardiographic characteristics of insulin-sensitive (IS) and IR patients with PAH. METHODS: This was a prospective cohort study including well-phenotyped patients with PAH proven at cardiac catheterization. Patients were classified as IS or IR on the basis of the well-validated triglyceride/high-density lipoprotein-cholesterol ratio...
July 2014: Journal of Heart and Lung Transplantation
Andrew N Rassi, Wael Aljaroudi, Sahar Naderi, M Chadi Alraies, Venu Menon, Leonardo Rodriguez, Richard Grimm, Brian Griffin, Wael A Jaber
BACKGROUND: Patients with aortic stenosis (AS) often undergo exercise echocardiography. Diastolic dysfunction (DD) is frequently associated with AS but little is known about its impact on functional capacity (FC). We sought to determine the relationship between DD and FC and their impact on mortality and need for aortic valve replacement (AVR) in patients with AS. METHODS AND RESULTS: Data was analyzed for consecutive patients with any degree of AS undergoing exercise stress echocardiography between 2000 and 2010 at our institution...
December 2013: Cardiovascular Diagnosis and Therapy
Hyungseop Kim, Hye-Soon Kim, Hyuck-Jun Yoon, Hyoung-Seob Park, Yun-Kyeong Cho, Chang-Wook Nam, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim
Arterial stiffness is an important risk factor of impaired left ventricular (LV) diastolic function as well as systolic dysfunction. The cardio-ankle vascular index (CAVI) and the ambulatory arterial stiffness index (AASI) can evaluate arteriosclerosis. We analyzed the relationship between arterial stiffness and diastolic function, and then compared the two methodologies to assess which method could serve as a more informative tool for diastology. In total, 136 patients with hypertension underwent 24-h ambulatory blood pressure monitoring (ABPM) and echocardiography including ventricular arterial coupling (VAC)...
2014: Clinical and Experimental Hypertension: CHE
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