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Twin pregnancies

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https://www.readbyqxmd.com/read/28742216/the-fetuses-at-risk-approach-survival-analysis-from-a-fetal-perspective
#1
K S Joseph, Michael S Kramer
Several phenomena in contemporary perinatology create challenges for analyzing pregnancy outcomes. These include recent increases in iatrogenic delivery at late preterm and early term gestation which are incongruent with the belief that stillbirth and neonatal death risk decrease exponentially with advancing gestational age. Perinatal epidemiologists have also puzzled over the paradox of intersecting birth weight- and gestational age-specific perinatal mortality curves for decades. For example, neonatal mortality rates among preterm infants of women who smoke are substantially lower than neonatal mortality rates among preterm infants of non-smoking women, whereas the reverse pattern occurs at term gestation...
July 25, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28738475/-trend-of-caesarean-section-rate-and-puerpera-characteristics-based-on-robson-classification
#2
J X Wang, H Q Sun, K Huang, X F Zheng, F B Tao
Objective: To analyze the trend in caesarean section rate and puerpera characteristics in hospital, and provide valuable information for maternal and child health policy making and clinical practice. Methods: A total of 12 041 women who delivered in the affiliated Chaohu Hospital of Anhui Medical University from October 1, 2010 to September 30, 2016 were selected. Based on Robson classification system, changes in the rate of caesarean delivery as well as its relationship with two-child policy and infant sex ratio were analyzed...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28738300/paternal-and-maternal-preconception-urinary-phthalate-metabolite-concentrations-and-child-behavior
#3
Carmen Messerlian, David Bellinger, Lidia Mínguez-Alarcón, Megan E Romano, Jennifer B Ford, Paige L Williams, Antonia M Calafat, Russ Hauser, Joseph M Braun
BACKGROUND: Prenatal phthalate exposure has been associated with behavioral problems and lower performance on measures of cognitive ability in children. However, the potential effect of phthalate exposure during the sensitive preconception period is unknown. OBJECTIVES: To estimate the association of maternal and paternal preconception urinary phthalate metabolite concentrations with child behavior and evaluate potential modification by child sex. METHODS: We used data from 166 children (111 singletons, 26 pairs of twins, and 1 set of triplets) born to 134 mothers and 100 fathers participating in a prospective preconception cohort study of subfertile couples from the Massachusetts General Hospital Fertility Center...
July 21, 2017: Environmental Research
https://www.readbyqxmd.com/read/28728213/performance-of-non-invasive-prenatal-screening-for-fetal-aneuploidy-in-twin-pregnancies-a-meta-analysis
#4
Hong Liao, Shanling Liu, He Wang
OBJECTIVE: The objective of this study was to review the published studies of non-invasive prenatal screening (NIPS) in twin pregnancies and to evaluate the performance for screening fetal trisomies 21, 18, and 13 in twin pregnancies. METHOD: Ten eligible studies were included in this meta-analysis. Data analysis, heterogeneity exploring, meta-regression and subgroup analysis were all conducted with Meta-DiSc 1.4. Quality assessments were carried out with the Quality Assessment Tool for Diagnostic Accuracy Studies (QUADAS-2)...
July 20, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28727976/monozygotic-twins-discordant-for-trisomy-13-a-case-of-trisomic-rescue-supporting-the-continued-need-for-first-trimester-ultrasound
#5
Patrick McFadden, Sarah Smithson, Robert Massaro, Jialing Huang, Gail T Prado, Wendy Shertz
Monozygotic twins with discordant karyotypes for trisomy 13 are rare. We report a case of a spontaneously conceived pregnancy who presented with first-trimester ultrasound finding of umbilical cord cyst and increased nuchal translucency in Twin A and no abnormalities in Twin B. Amniocentesis revealed 47,XY,+13 karyotype in Twin A and 46,XY karyotype in Twin B. Selective fetal reduction was performed for Twin A. Twin B was delivered at 32 weeks gestation with normal phenotype. Peripheral blood karyotype revealed 15% mosaicism for trisomy 13 and skin fibroblast revealed 46,XY karyotype...
July 2017: Pediatric and Developmental Pathology
https://www.readbyqxmd.com/read/28725171/spontaneous-twin-pregnancy-with-live-births-after-cryopreservation-and-re-implantation-of-ovarian-tissue
#6
Milan Milenkovic, Mats Brännström, Cesar Diaz-Garcia, Kersti Lundin, Ulrika Selleskog, Brita Söderlund, Ali Khatibi, Berit Gull, Hans Bokström, Claudia Mateoiu, Levent M Akyürek, Ann Thurin-Kjellberg
No abstract text is available yet for this article.
2017: Gynecological Surgery
https://www.readbyqxmd.com/read/28724477/oliver-sacks-our-correspondence-about-twins-twin-research-vanishing-twins-syndrome-discordant-sex-in-mz-twins-pregnancy-outcomes-in-ivf-and-icsi-conceived-twins-print-and-media-superfetated-twins-twins-discordant-for-smoking-twins-in-fashion-yale-university
#7
Nancy L Segal
The late neurologist and author, Oliver Sacks, published an insightful 1986 review of Marjorie Wallace's book, The Silent Twins, in the New York Times. Taking exception to his assertion about Sir Francis Galton, I wrote a letter to the Times' editor. The letter was unpublished, but it brought a wonderful response from Sacks himself that is reproduced and examined. Next, brief reviews of twin research concerning the vanishing twin syndrome (VTS), discordant sex in a monozygotic (MZ) twin pair, and multiple pregnancy outcomes from assisted reproductive technology (ART) are presented...
August 2017: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/28721929/obstetric-hemorrhages-at-the-chu-yalgado-ou%C3%A3-draogo-of-ouagadougou%C3%A2-etiological-therapeutic-and-prognostic-aspects
#8
D P Kain, R D Ajavon, H Zamané, S Kiemtore, Y A Sawadogo, I Ouédraogo
To evaluate the maternal and perinatal prognosis of obstetric hemorrhages in the maternity department of the Yalgado Ouédraogo University Hospital of Ouagadougou. This descriptive cross-sectional study conducted in the four-month period from April through July 2015 included all women consulting on an emergency basis for vaginal bleeding during pregnancy at or after 28 weeks of gestation, or during labor, delivery, or the postpartum period. Obstetric hemorrhages accounted for 6% of admissions. The women's mean age was 27...
July 19, 2017: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/28719330/case-report-microcephaly-in-twins-due-to-the-zika-virus
#9
Victor S Santos, Sheila J G Oliveira, Ricardo Q Gurgel, Dorothy R R Lima, Cliomar A Dos Santos, Paulo R S Martins-Filho
Recent studies have demonstrated an association between congenital Zika virus (ZIKV) infection and microcephaly; however, to date, there have been no reports on the consequences of ZIKV infection on fetuses in twin pregnancies. Herein, we reported on the first case of a monochorionic diamniotic (MCDA) twin pregnancy having ZIKV-related microcephaly. Our findings suggested that, in an MCDA twin pregnancy, the ZIKV may cause infection in both fetuses, resulting in severe abnormalities in the central nervous system due to neural cell destruction and the disruption of the normal development processes of the brain...
July 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28718952/facets-of-clinical-appearance-and-aetiology-in-an-unusual-bovine-amorphus-globosus
#10
J Weber, N Rudolph, M Freick
Amorphus globosus is a rare entity, more common in the cow but also reported in mares, buffaloes and goats. In respect of both development and clinical presentation, this abnormity can be evolved very variably. Previously, it has been discussed whether it is a form of twin pregnancy or placental teratoma. This case report deals with morphology and genetic observations in an unusual bovine amorphus globosus exhibiting a rudimentary clitoris and vulva, gut-like structures and rudimentary bones. The amorphus globosus was shown to be dizygotic to the normal male twin using the BovineSNP50 v2 BeadChip and had a genetical female sex...
July 18, 2017: Anatomia, Histologia, Embryologia
https://www.readbyqxmd.com/read/28709445/twin-twin-transfusion-syndrome-study-protocol-for-developing-disseminating-and-implementing-a-core-outcome-set
#11
Asma Khalil, Helen Perry, James Duffy, Keith Reed, Ahmet Baschat, Jan Deprest, Kurt Hecher, Liesbeth Lewi, Enrico Lopriore, Dick Oepkes
BACKGROUND: Twin-Twin Transfusion Syndrome (TTTS) is associated with an increased risk of perinatal mortality and morbidity. Several treatment interventions have been described for TTTS, including fetoscopic laser surgery, amnioreduction, septostomy, expectant management, and pregnancy termination. Over the last decade, fetoscopic laser surgery has become the primary treatment. The literature to date reports on many different outcomes, making it difficult to compare results or combine data from individual studies, limiting the value of research to guide clinical practice...
July 14, 2017: Trials
https://www.readbyqxmd.com/read/28708526/progesterone-concentration-and-lambing-rate-of-karakul-ewes-treated-with-prostaglandin-and-gnrh-combined-with-the-ram-effect-during-breeding-and-non-breeding-seasons
#12
A Mirzaei, M Mohebbi-Fani, A Omidi, A Boostani, S Nazifi, H R Mahmoodian-Fard, M Chahardahcherik
The combination of ram effect with two injections of PGF2α 10-days apart and the same protocol plus an additional injection of GnRH prior to the first injection of PGF2α were examined in Karakul ewes during breeding and non-breeding seasons, respectively. Plasma progesterone (P4) concentrations (to detect the presence of active corpus luteum), twin lambing, litter size and synchronization of lambing were evaluated. In each study 70 ewes (2-4 years old) were divided to a treatment (n = 40) and a control (n = 30) group...
June 9, 2017: Theriogenology
https://www.readbyqxmd.com/read/28708503/effect-of-dietary-supplementation-of-omega-3-polyunsaturated-fatty-acid-pufa-rich-fish-oil-on-reproductive-performance-of-the-goat-capra-hircus
#13
Ajit Singh Mahla, Ravjibhai K Chaudhari, Atul Kumar Verma, Amit Kumar Singh, Sanjay Kumar Singh, Gyanendra Singh, Mihir Sarkar, Narayan Dutta, Harendra Kumar, Narayanan Krishnaswamy
Dietary supplementation of n-3 PUFA decreases the luteolytic PGF2α and improves the pregnancy rate in the dairy cow. However, its effect in the goat is not known. Accordingly, we studied the effect of supplementation of n-3 PUFA rich Fish oil (FO) on different reproductive events in the goat. Cycling goats (n = 30) were divided into two equal groups and fed an isocaloric and isonitrogenous diet supplemented with either FO (TRT; n = 15) or palm oil (PO) (CON; n = 15) @ 0.6 mL/kg body weight for 72 days during the breeding season...
May 26, 2017: Theriogenology
https://www.readbyqxmd.com/read/28707771/effect-of-vaginal-progesterone-in-tocolytic-therapy-during-preterm-labor-in-twin-pregnancies-secondary-analysis-of-a-placebo-controlled-randomized-trial
#14
Wagner R Hernandez, Rossana P V Francisco, Roberto E Bittar, Ursula T Gomez, Marcelo Zugaib, Maria L Brizot
AIM: Our aim was to investigate the effect of the prophylactic use of vaginal progesterone on the latency period from the initiation of tocolytic therapy to delivery in twin pregnancies with preterm labor. METHODS: This study was a secondary analysis of a randomized, double-blind, placebo-controlled trial of twin pregnancies in mothers who were exposed to a 200 mg vaginal progesterone ovule or a placebo ovule daily from 18 to 34 weeks gestation. Patients who were administered tocolysis with Atosiban because of preterm labor were included...
July 14, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28706170/-multiple-factors-in-the-second-trimester-of-pregnancy-on-preterm-labor-symptoms-and-preterm-birth
#15
Jeung Im Kim, Mi Ock Cho, Gyu Yeon Choi
PURPOSE: The aim of this study was to determine the influence of various factors on preterm labor symptoms (PLS) and preterm birth (PB). METHODS: This prospective cohort study included 193 women in the second stage of pregnancy. Multiple characteristics including body mass index (BMI), smoking, and pregnancy complications were collected through a self-report questionnaire. Pregnancy stress and PLS were each measured with a related scale. Cervical length and birth outcome were evaluated from medical charts...
June 2017: Journal of Korean Academy of Nursing
https://www.readbyqxmd.com/read/28704846/the-effect-of-treated-overt-hypothyroidism-on-outcomes-in-twin-pregnancies
#16
Jonathan Y Rosner, Nathan S Fox, Daniel Saltzman, Andrei Rebarber, Simi Gupta
No abstract text is available yet for this article.
July 13, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28704197/expectant-management-in-di-chorionic-pregnancies-complicated-by-discordant-anomalous-twin
#17
Paola Algeri, Francesca M Russo, Maddalena Incerti, Sabrina Cozzolino, Francesca Pelizzoni, Davido P Bernasconi, Luca Montanelli, Luca Locatelli, Patrizia Vergani
Fetal malformations are more frequent in twins than in singletons. The aim of our study was to define the influence of a malformed twin on di-chorionic pregnancy outcomes. We performed a retrospective cohort study of di-chorionic pregnancies delivered between 2000 and 2015. Exclusion criteria were: both twins affected by fetal malformations, double intra-uterine fetal death in pregnancies without fetal malformation, selective feticide and therapeutic pregnancy termination. We compared maternal and fetal outcomes of di-chorionic pregnancies not complicated by fetal malformations with pregnancies affected by a single malformed fetus with conservative management...
July 12, 2017: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/28695721/aortic-isthmus-shunt-dynamics-in-normal-and-complicated-monochorionic-pregnancies
#18
Viola Seravalli, Dana Block-Abraham, Cyrethia McShane, Sarah Millard, Ahmet Baschat, Jena Miller
OBJECTIVE: To study fetal aortic isthmus (AoI) shunt dynamics in monochorionic (MC) twins. METHODS: Normal and complicated MC pregnancies were prospectively enrolled. The relationship of isthmus flow index (IFI) with Doppler parameters of umbilical artery (UA), descending aorta (DAo), middle cerebral artery (MCA), and ductus venosus (DV), and with left and right ventricular cardiac output and stroke volume was studied. RESULTS: The IFI was obtained in 180 examinations from 48 pregnancies (24 twin-twin-transfusion syndrome, TTTS; 4 selective intrauterine growth restriction, sIUGR; 12 TTTS+sIUGR; 8 uncomplicated)...
July 11, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28691603/dichorionic-twins-discordant-for-massive-perivillous-fibrinoid-deposition-report-of-a-case-and-review-of-the-literature
#19
Ona Faye-Petersen, Adrienne Sauder, Ydamis Estrella, Debra S Heller
Massive perivillous fibrinoid deposition (MFD) and maternal floor infarction (MFI) are lesions of unknown etiology associated with poor perinatal outcomes, including fetal intrauterine growth restriction and neurodevelopmental injury, high risks of pregnancy loss, and recurrence in subsequent gestations. MFI comprises massive intervillous fibrinoid deposition concentrated at the maternal floor. MFD is a similar lesion but is diffuse within the parenchyma. MFD/MFI lesions represent a spectrum of severity of cloak-like perivillous fibrinoid deposition, and there is mounting evidence that, often, they represent sequelae of immune-mediated phenomena and/or an imbalance in factors that normally maintain the fluidity of blood in the maternal space...
July 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28691320/use-of-ultrasound-shear-wave-elastography-to-evaluate-change-in-cervical-stiffness-during-pregnancy
#20
Tetsuo Ono, Daisuke Katsura, Kazutaka Yamada, Kaori Hayashi, Akiko Ishiko, Shunichiro Tsuji, Fuminori Kimura, Kentaro Takahashi, Takashi Murakami
AIM: The aim of this study was to evaluate the usefulness of shear-wave elastography (SWE) for measuring change in cervical stiffness during pregnancy, with regions of interest (ROI) designed for easy identification. METHODS: A total of 280 women were enrolled in this study. SWE was performed at a routine prenatal visit. A measurement area was chosen at the anterior part of the cervix, and a circular ROI 5 mm in diameter was set at two points, 5-10 mm (lower point) and 15-20 mm (upper point) from the external cervical os...
July 10, 2017: Journal of Obstetrics and Gynaecology Research
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