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https://www.readbyqxmd.com/read/27914024/laparoscopic-hepatectomy-for-hcc-in-elderly-patients-risks-and-feasibility
#1
Bruno Amato, Giovanni Aprea, Davide De Rosa, Marco Milone, Lorenza di Domenico, Maurizio Amato, Rita Compagna, Mario Santoro, Louis Banka Johnson, Alessandro Sanguinetti, Andrea Polistena, Nicola Avenia
BACKGROUND: Laparoscopic liver resection (LLR) appears to be safe and effective as open liver resection (OLR) for hepatocellular carcinoma (HCC). However, studies comparing LLR with ORL in elderly patients are limited. The purpose of this study is to compare the clinical outcomes of LLR versus OLR for HCC in elderly patients. METHODS: A retrospective analysis was made comparing laparoscopic (n = 11) and open (n = 18) liver resections in elderly patients performed at the University of Naples "Federico II" between January 2010 and December 2014...
December 2, 2016: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/27871559/quality-of-recovery-from-anesthesia-of-patients-undergoing-balanced-or-total-intravenous-general-anesthesia-prospective-randomized-clinical-trial
#2
Eduardo Toshiyuki Moro, Fábio Caetano Oliveira Leme, Bernardo Roveda Noronha, Gustavo Farinha Pinto Saraiva, Nathália Vianna de Matos Leite, Laís Helena Camacho Navarro
STUDY OBJECTIVES: The aim of the present study was to assess the quality of recovery from anesthesia of patients subjected to otorhinolaryngological (ORL) surgery under balanced or total intravenous general anesthesia by means of Quality of Recovery-40 (QoR-40) questionnaire. DESIGN: Prospective randomized clinical trial. SETTING: The setting is at an operating room, a postoperative recovery area, and a hospital ward. PATIENTS: One-hundred thirty American Society of Anesthesiologists physical status I or II patients scheduled to undergo general anesthesia for ORL interventions under remifentanil, in combination with sevoflurane (balanced technique) or propofol (total intravenous anesthesia)...
December 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27845741/cst-an-herbal-formula-exerts-anti-obesity-effects-through-brain-gut-adipose-tissue-axis-modulation-in-high-fat-diet-fed-mice
#3
AbuZar Ansari, Shambhunath Bose, Mukesh Kumar Yadav, Jing-Hua Wang, Yun-Kyung Song, Seong-Gyu Ko, Hojun Kim
The brain, gut, and adipose tissue interact to control metabolic pathways, and impairment in the brain-gut-adipose axis can lead to metabolic disorders, including obesity. Chowiseungcheng-tang (CST), a herbal formulation, is frequently used to treat metabolic disorders. Here, we investigated the anti-obesity effect of CST and its link with brain-gut-adipose axis using C57BL/6J mice as a model. The animals were provided with a normal research diet (NRD) or high-fat diet (HFD) in absence or presence of CST or orlistat (ORL) for 12 weeks...
November 11, 2016: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/27806756/-comparison-between-computer-aided-simulation-and-dental-model-orthognathic-surgery-for-the-treatment-of-patients-with-mandibular-excess-and-facial-asymmetries
#4
S Y Shen, T T Chen, C P Lu, T F Jiang, X D Wang, G F Shen
Objective: To evaluate the results of the orthognathic surgery with computer aided simulation-three-dimensional(3D) printed surgical guide and dental model surgery in the treatmemt of patients with mandibular excess and facial asymmetries. Methods: The coordinate system was built in ProPlan CMF 2.0 software, and the horizontal plane consisted of PoL, PoR, OrL, middle sagittal plane through nasion point and basion point and the plane perpendicular to the horizontal plane, coronoid plane through nasion point and the plane perpendicular to the horizontal plane and middle sagittal plane...
November 9, 2016: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/27780122/analysis-of-injury-severity-of-large-truck-crashes-in-work-zones
#5
Mohamed Osman, Rajesh Paleti, Sabyasachee Mishra, Mihalis M Golias
Work zones are critical parts of the transportation infrastructure renewal process consisting of rehabilitation of roadways, maintenance, and utility work. Given the specific nature of a work zone (complex arrangements of traffic control devices and signs, narrow lanes, duration) a number of crashes occur with varying severities involving different vehicle sizes. In this paper we attempt to investigate the causal factors contributing to injury severity of large truck crashes in work zones. Considering the discrete nature of injury severity categories, a number of comparable econometric models were developed including multinomial logit (MNL), nested logit (NL), ordered logit (ORL), and generalized ordered logit (GORL) models...
October 22, 2016: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/27772735/retinal-imaging-and-axonal-degeneration-in-later-onset-multiple-sclerosis
#6
Konstantin Huhn, Robert Lämmer, Hanna Zimmermann, Alexandra Lämmer, Anne Waschbisch, Kathrin Utz, René Markus Gieß, Friedemann Paul, Ralf A Linker, De-Hyung Lee
BACKGROUND: Multiple Sclerosis (MS) is a chronic inflammatory disease of the CNS typically affecting younger adults and resulting in neuro-axonal degeneration already at early stages of the disease. Less is known about the effects of a later disease onset (LOMS, onset >50years of age). Analysis of retinal layers by optical coherence tomography (OCT) is a non-invasive method to investigate retinal and neuro-axonal degeneration. We applied OCT to detect differences in retinal damage depending on a later disease manifestation...
November 15, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27760261/macular-inner-retinal-layer-thickening-and-outer-retinal-layer-damage-correlate-with-visual-acuity-during-remission-in-behcet-s-disease
#7
Dan Cheng, Yuqin Wang, Shenghai Huang, Qiuyan Wu, Qi Chen, Meixiao Shen, Fan Lu
Purpose: To identify macular intraretinal layer changes of patients in remission from Behcet's disease (BD) of short and long duration and evaluate the associations with visual acuity (VA). Methods: Thirty-two eyes from 26 BD patients were enrolled, including 16 eyes with a duration less than 3 years (0.5-2.5 years; BD1) and 16 eyes of longer duration (3-12 years; BD2). Their intraretinal layer thicknesses and integrity of ellipsoid zone (EZ) and interdigitation zone (IZ) were evaluated by spectral-domain optical coherence tomography (SD-OCT)...
October 1, 2016: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/27759020/coherent-perfect-absorption-in-one-sided-reflectionless-media
#8
Jin-Hui Wu, M Artoni, G C La Rocca
In optical experiments one-sided reflectionless (ORL) and coherent perfect absorption (CPA) are unusual scattering properties yet fascinating for their fundamental aspects and for their practical interest. Although these two concepts have so far remained separated from each other, we prove that the two phenomena are indeed strictly connected. We show that a CPA-ORL connection exists between pairs of points lying along lines close to each other in the 3D space-parameters of a realistic lossy atomic photonic crystal...
October 19, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27705866/joint-sparse-representation-and-embedding-propagation-learning-a-framework-for-graph-based-semisupervised-learning
#9
Xiaobing Pei, Chuanbo Chen, Yue Guan
In this paper, we propose a novel graph-based semisupervised learning framework, called joint sparse representation and embedding propagation learning (JSREPL). The idea of JSREPL is to join EPL with sparse representation to perform label propagation. Like most of graph-based semisupervised propagation learning algorithms, JSREPL also constructs weights graph matrix from given data. Different from classical approaches which build weights graph matrix and estimate the labels of unlabeled data in sequence, JSREPL simultaneously builds weights graph matrix and estimates the labels of unlabeled data...
September 28, 2016: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/27663713/proceedings-of-the-rami-section-of-otorhinolaryngology-head-and-neck-surgery-orl-hns-spring-meeting-saturday-23rd-april-2016-sheraton-hotel-athlone-co-westmeath
#10
(no author information available yet)
No abstract text is available yet for this article.
September 23, 2016: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/27663712/proceedings-of-the-rami-section-of-otorhinolaryngology-head-and-neck-surgery-orl-hns-winter-meeting-friday-11th-december-2015-education-and-research-centre-royal-victoria-eye-and-ear-hospital-adelaide-road-dublin-2
#11
https://www.readbyqxmd.com/read/27660683/treatment-of-pain-with-spirocylic-cyclohexane-derivatives-having-dual-specificity-for-orl-1-and-%C3%AE-opioid-receptors
#12
EDITORIAL
Gerard Rosse
No abstract text is available yet for this article.
September 8, 2016: ACS Medicinal Chemistry Letters
https://www.readbyqxmd.com/read/27598984/interaction-strength-interpolation-method-for-main-group-chemistry-benchmarking-limitations-and-perspectives
#13
Eduardo Fabiano, Paola Gori-Giorgi, Michael Seidl, Fabio Della Sala
We have tested the original interaction-strength-interpolation (ISI) exchange-correlation functional for main group chemistry. The ISI functional is based on an interpolation between the weak and strong coupling limits and includes exact-exchange as well as the Görling-Levy second-order energy. We have analyzed in detail the basis-set dependence of the ISI functional, its dependence on the ground-state orbitals, and the influence of the size-consistency problem. We show and explain some of the expected limitations of the ISI functional (i...
October 11, 2016: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/27513601/resection-of-the-ethmoidal-crest-in-sphenopalatine-artery-surgery
#14
Paulo Saraceni Neto, Leonardo Mendes Acatauassu Nunes, Fabio de Azevedo Caparroz, Luciano Lobato Gregorio, Rafael de Paula E Silva Felice de Souza, Juliana Caminha Simões, Eduardo Macoto Kosugi
BACKGROUND: In severe cases of epistaxis, in spite of several procedures described in the literature for its management, surgical treatment has been recognized by most authors as 1 of the most effective, especially when it includes ligation and/or electrocoagulation of the nasal branches of the sphenopalatine artery. The objective of this study is to determine the importance of ethmoid crest resection during sphenopalatine artery surgery, in the management of severe epistaxis. METHODS: We report a double-blinded randomized clinical trial, in which intervention was the ethmoid crest resection during electrocoagulation of the sphenopalatine artery...
August 11, 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27299894/palliative-treatment-standards-for%C3%A2-head-and-neck-squamous-cell-carcinoma-survey%C3%A2-of%C3%A2-clinical%C3%A2-routine%C3%A2-in%C3%A2-german-speaking-countries
#15
S Laban, J Kimmeyer, R Knecht, T K Hoffmann, C-J Busch, J A Veit, N Möckelmann, T Kurzweg
BACKGROUND: The EXTREME (Erbitux in First-Line Treatment of Recurrent and Metastatic Head and Neck Squamous Cell Carcinoma) protocol is generally considered the gold standard in palliative first-line treatment. However, there is some disagreement about its effectivity, toxicity, and applicability in daily clinical routine. The purpose of this cross-sectional survey was to describe the palliative treatment offered in German-speaking countries. METHODS: From November 2013 to July 2014, 204 departments of otorhinolaryngology (ORL) in Germany, Austria, and the German-speaking parts of Switzerland were contacted and invited to take part in a web-based survey on the treatment of HNSCC...
July 2016: HNO
https://www.readbyqxmd.com/read/27114686/ethnobotanical-study-of-medicinal-plants-used-for-the-treatment-of-malaria-in-the-plateau-region-togo
#16
Kodjovi Agbodeka, Holaly E Gbekley, Simplice D Karou, Kokou Anani, Amegnona Agbonon, Tchadjobo Tchacondo, Komlan Batawila, Jacques Simpore, Messanvi Gbeassor
BACKGROUND: In Togo, malaria constitutes a major public health problem but, until now, the population still mostly relies on herbal medicine for healing. This study aimed to document medicinal plants used for malaria therapy in the Plateau region of the country. METHODOLOGY: Semi-structured questionnaire interviews were used to gather ethnobotanical and sociodemographic data from traditional healers of the study area. RESULTS: A total of 61 plants species belonging to 33 families were found to be in use for malaria therapy in the Plateau region...
March 2016: Pharmacognosy Research
https://www.readbyqxmd.com/read/27107728/international-pediatric-orl-group-ipog-laryngomalacia-consensus-recommendations
#17
REVIEW
John Carter, Reza Rahbar, Matthew Brigger, Kenny Chan, Alan Cheng, Sam J Daniel, Alessandro De Alarcon, Noel Garabedian, Catherine Hart, Christopher Hartnick, Ian Jacobs, Bryan Liming, Richard Nicollas, Seth Pransky, Gresham Richter, John Russell, Michael J Rutter, Anne Schilder, Richard J H Smith, Julie Strychowsky, Robert Ward, Karen Watters, Michelle Wyatt, George Zalzal, Karen Zur, Dana Thompson
OBJECTIVE: To provide recommendations for the comprehensive management of young infants who present with signs or symptoms concerning for laryngomalacia. METHODS: Expert opinion by the members of the International Pediatric Otolaryngology Group (IPOG). RESULTS: Consensus recommendations include initial care and triage recommendations for health care providers who commonly evaluate young infants with noisy breathing. The consensus statement also provides comprehensive care recommendations for otolaryngologists who manage young infants with laryngomalacia including: evaluation and treatment considerations for commonly debated issues in laryngomalacia, initial work-up of infants presenting with inspiratory stridor, treatment recommendations based on disease severity, management of the infant with feeding difficulties, post-surgical treatment management recommendations, and suggestions for acid suppression therapy...
July 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27102548/infection-pattern-and-transmission-potential-of-chikungunya-virus-in-two-new-world-laboratory-adapted-aedes-aegypti-strains
#18
Shengzhang Dong, Asher M Kantor, Jingyi Lin, A Lorena Passarelli, Rollie J Clem, Alexander W E Franz
Chikungunya virus (CHIKV) is an emerging mosquito-borne virus belonging to the Togaviridae, which is transmitted to humans by Aedes aegypti and Ae. albopictus. We describe the infection pattern of CHIKV in two New World Ae. aegypti strains, HWE and ORL. Both mosquito strains were susceptible to the virus but showed different infection patterns in midguts and salivary glands. Even though acquisition of a bloodmeal showed moderate levels of apoptosis in midgut tissue, there was no obvious additional CHIKV-induced apoptosis detectable during midgut infection...
2016: Scientific Reports
https://www.readbyqxmd.com/read/27059153/expanded-endoscopic-endonasal-surgery-for-advanced-stage-juvenile-angiofibromas-a-retrospective-multi-center-study
#19
C Langdon, P Herman, B Verillaud, R L Carrau, D Prevedello, P Nicolai, A Schreiber, G Padoan, P Castelnuovo, M Bernal-Sprekelsen
OBJECTIVES: Endoscopic resection has become an established surgical option for most juvenile nasopharyngeal angiofibromas (JNA). However, surgical management of JNA with intracranial extension remains challenging. This retrospective multicenter study reviews a series of patients with advanced stage JNA treated via endonasal/endoscopic approach. METHODS: The experience of five academic tertiary or quaternary care ORL-HNS Departments were included. Medical records of all patients operated for JNA staged as Radkowski stage IIIA or IIIB were reviewed...
September 2016: Rhinology
https://www.readbyqxmd.com/read/27050151/genetically-defined-novel-oral-squamous-cell-carcinoma-cell-lines-for-the-development-of-molecular-therapies
#20
Muhammad Zaki Hidayatullah Fadlullah, Ivy Kim-Ni Chiang, Kalen R Dionne, Pei San Yee, Chai Phei Gan, Kin Kit Sam, Kai Hung Tiong, Adrian Kwok Wen Ng, Daniel Martin, Kue Peng Lim, Thomas George Kallarakkal, Wan Mahadzir Wan Mustafa, Shin Hin Lau, Mannil Thomas Abraham, Rosnah Binti Zain, Zainal Ariff Abdul Rahman, Alfredo Molinolo, Vyomesh Patel, J Silvio Gutkind, Aik Choon Tan, Sok Ching Cheong
Emerging biological and translational insights from large sequencing efforts underscore the need for genetically-relevant cell lines to study the relationships between genomic alterations of tumors, and therapeutic dependencies. Here, we report a detailed characterization of a novel panel of clinically annotated oral squamous cell carcinoma (OSCC) cell lines, derived from patients with diverse ethnicity and risk habits. Molecular analysis by RNAseq and copy number alterations (CNA) identified that the cell lines harbour CNA that have been previously reported in OSCC, for example focal amplications in 3q, 7p, 8q, 11q, 20q and deletions in 3p, 5q, 8p, 18q...
May 10, 2016: Oncotarget
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