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https://www.readbyqxmd.com/read/29666821/probiotics-for-the-control-of-helminth-zoonosis
#1
REVIEW
Abadi Amare Reda
This paper is a comprehensive, concise, and an up to date review about probiotics effect and mechanisms against helminth infections of zoonotic importance. Zoonoses are diseases that can be transmitted from animals to humans in a reversible way. Despite zoonotic helminth diseases being still a challenge to the public health and the agriculture industries globally, they were still neglected in both human and veterinary medicine. Moreover, the increasing emergence of anthelmintic drug resistance constitutes failures of most disease control strategies, alarming for a quest to new alternative control approaches...
2018: Journal of Veterinary Medicine
https://www.readbyqxmd.com/read/29660405/microbiome-mediated-bile-acid-modification-role-in-intestinal-drug-absorption-and-metabolism
#2
REVIEW
Elaine F Enright, Brendan T Griffin, Cormac G M Gahan, Susan A Joyce
Once regarded obscure and underappreciated, the gut microbiota (the microbial communities colonizing the gastrointestinal tract) is gaining recognition as an influencer of many aspects of human health. Also increasingly apparent is the breadth of interindividual variation in these co-evolved microbial-gut associations, presenting novel quests to explore implications for disease and therapeutic response. In this respect, the unearthing of the drug-metabolizing capacity of the microbiota has provided impetus for the integration of microbiological and pharmacological research...
April 13, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29660058/histological-parameters-to-evaluate-intestinal-health-on-broilers-challenged-with-eimeria-and-clostridium-perfringens-with-or-without-enramycin-as-growth-promoter
#3
B L Belote, A Tujimoto-Silva, P H Hümmelgen, A W D Sanches, J C S Wammes, R M Hayashi, E Santin
The maintenance of integrity of the gastrointestinal tract is an important aspect for animal productivity, since it is able to absorb nutrients more efficiently and serves as a barrier against microorganisms. To control agents detrimental to intestinal integrity, growth-promoting antibiotics (AGP) are used, which reduce the number of toxin-producing microorganisms in the intestinal lumen, acting as anti-inflammatory agents. There is a demand for restriction of use of AGP in animal feed, but there are few studies showing what parameters we should observe to search for alternative additives...
April 5, 2018: Poultry Science
https://www.readbyqxmd.com/read/29659916/human-gut-microbiota-predicts-susceptibility-to-vibrio-cholerae-infection
#4
Firas S Midani, Ana A Weil, Fahima Chowdhury, Yasmin A Begum, Ashraful I Khan, Meti D Debela, Heather K Durand, Aspen T Reese, Sai N Nimmagadda, Justin D Silverman, Crystal N Ellis, Edward T Ryan, Stephen B Calderwood, Jason B Harris, Firdausi Qadri, Lawrence A David, Regina C LaRocque
Background: Cholera is a public health problem worldwide and the risk factors for infection are only partially understood. Methods: We prospectively studied household contacts of cholera patients to compare those who were infected with those who were not. We constructed predictive machine learning models of susceptibility using baseline gut microbiota data. We identified bacterial taxa associated with susceptibility to Vibrio cholerae infection and tested these taxa for interactions with V...
April 12, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29651187/effect-of-encapsulation-on-viability-of-bifidobacterium-longum-cfr815j-and-physiochemical-properties-of-ice-cream
#5
Ankita Kataria, Sajan C Achi, Prakash M Halami
The health beneficial attributes of bifidobacteria and its safe association with the host gut has increased its significance as a probiotic. However delivering probiotic bifidobacteria with Minimum Biological Value (MBV) through product has always been a challenge. In the present study, an attempt was made to maintain the viability of native isolate of Bifidobacterium longum CFR 815j and deliver through ice-cream. B. longum CFR815j was microencapsulated in alginate starch capsules by emulsification followed by evaluation of bead stability in simulated gastrointestinal conditions...
June 2018: Indian Journal of Microbiology
https://www.readbyqxmd.com/read/29651112/behavioural-medicine-and-gastrointestinal-disorders-the-promise-of-positive-psychology
#6
REVIEW
Laurie Keefer
Psychosocial risk factors linked to brain-gut dysregulation are prevalent across the spectrum of gastrointestinal disorders and are associated with poor patient outcomes. Robust and reproducible data in the areas of behavioural intervention science and the brain-gut axis have led to major advances in patient care, including the routine use of brain-gut psychotherapies to manage digestive symptoms and optimize coping. The logical next step for the emerging field of psychogastroenterology is to develop a scientific framework that enables the identification of those individual characteristics and coping styles that buffer patients against the negative psychological effects of chronic gastrointestinal disorders...
April 12, 2018: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29649123/phytochemical-properties-and-nutrigenomic-implications-of-yacon-as-a-potential-source-of-prebiotic-current-evidence-and-future-directions
#7
REVIEW
Yang Cao, Zheng Feei Ma, Hongxia Zhang, Yifan Jin, Yihe Zhang, Frank Hayford
The human gut is densely populated with diverse microbial communities that are essential to health. Prebiotics and fiber have been shown to possess the ability to modulate the gut microbiota. One of the plants being considered as a potential source of prebiotic is yacon. Yacon is an underutilized plant consumed as a traditional root-based fruit in South America. Yacon mainly contains fructooligosaccharides (FOS) and inulin. Therefore, it has bifidogenic benefits for gut health, because FOS are not easily broken down by digestive enzymes...
April 12, 2018: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/29644870/a-novel-polyphenolic-prebiotic-and-probiotic-formulation-have-synergistic-effects-on-the-gut-microbiota-influencing-drosophila-melanogaster-physiology
#8
Susan Westfall, Nikita Lomis, Satya Prakash
The gut microbiota is a vast community of synergistic bacterial species providing health benefits to the host. Imbalances in the gut microbiota (dysbiosis) due to diet, antibiotic use, age and stress contribute to disease development including diabetes, obesity, colon cancer, inflammatory bowel disease, inflammaging and neurodegeneration. Fortunately, a probiotic regime with a diet rich in prebiotics may reverse dysbiosis promoting health and wellness in age. The current study designs, optimizes and tests a novel probiotic and synbiotic formulation consisting of three metabolically active probiotics Lactobacillus plantarum, Lactobacillus fermentum and Bifidobacteria infantis together with a novel polyphenol-rich prebiotic, Triphala...
April 12, 2018: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29644395/metabolic-phenotyping-of-malnutrition-during-the-first-1000-days-of-life
#9
REVIEW
Jordi Mayneris-Perxachs, Jonathan R Swann
Nutritional restrictions during the first 1000 days of life can impair or delay the physical and cognitive development of the individual and have long-term consequences for their health. Metabolic phenotyping (metabolomics/metabonomics) simultaneously measures a diverse range of low molecular weight metabolites in a sample providing a comprehensive assessment of the individual's biochemical status. There are a growing number of studies applying such approaches to characterize the metabolic derangements induced by various forms of early-life malnutrition...
April 11, 2018: European Journal of Nutrition
https://www.readbyqxmd.com/read/29643147/-ex-vivo-gut-culture-for-studying-differentiation-and-migration-of-small-intestinal-epithelial-cells
#10
Xiaofei Sun, Xing Fu, Min Du, Mei-Jun Zhu
Epithelial cultures are commonly used for studying gut health. However, due to the absence of mesenchymal cells and gut structure, epithelial culture systems including recently developed three-dimensional organoid culture cannot accurately represent in vivo gut development, which requires intense cross-regulation of the epithelial layer with the underlying mesenchymal tissue. In addition, organoid culture is costly. To overcome this, a new culture system was developed using mouse embryonic small intestine. Cultured intestine showed spontaneous peristalsis, indicating the maintenance of the normal gut physiological structure...
April 2018: Open Biology
https://www.readbyqxmd.com/read/29642683/effect-of-lactobacillus-salivarius-on-growth-performance-diarrhea-incidence-fecal-bacterial-population-and-intestinal-morphology-of-suckling-pigs-challenged-with-f4-enterotoxigenic-escherichia-coli
#11
Harutai Sayan, Pornchalit Assavacheep, Kris Angkanaporn, Anongnart Assavacheep
Objective: Gut health improvements were monitored with respect to growth performance, diarrhea incidence, fecal bacterial population and intestinal morphology of suckling pigs orally supplemented with live Lactobacillus salivarius oral suspensions and challenged with F4+ enterotoxigenic Escherichia coli (ETEC). Methods: Two groups of newborn pigs from 18 multiparous sows were randomly designated as non-supplemented (control: n=114 piglets) and L. salivarius supplemented groups (treatment: n=87 piglets)...
April 12, 2018: Asian-Australasian Journal of Animal Sciences
https://www.readbyqxmd.com/read/29629422/can-diet-influence-our-health-by-altering-intestinal-microbiota-derived-fecal-metabolites
#12
Qiang Lyu, Cheng-Chih Hsu
The human gastrointestinal tract harbors a diverse, highly mutualistic microbial flora which could produce a myriad of specialized metabolites. These specialized metabolites are the chemical cellphones that gut microflora use to communicate with their human host and could potentially be used to cure diseases. Chemical compounds in diet also shape the gut flora. In order to understand which and how the gut microbe-derived specialized metabolites affect human health, the "gut microbiome-metabolomic-human health axis" is thus proposed...
March 2018: MSystems
https://www.readbyqxmd.com/read/29628357/frailty-and-the-gut
#13
REVIEW
Antonio Di Sabatino, Marco Vincenzo Lenti, Lisa Cammalleri, Gino Roberto Corazza, Alberto Pilotto
Frailty, which is a syndrome that encompasses losses in physical, psychological and social domains, is responsible for enhanced vulnerability to endogenous and/or exogenous stressors. Frailty is a public health problem for an ageing society; however, it is poorly understood and often under-recognised in clinical settings. In particular, the impact of frailty on either intestinal functions, i.e. immune response, permeability, and absorption, or gut microbiota composition is as yet mostly unexplored. A better comprehension of the intestinal dysfunction occurring in the elderly would help in clarifying the mechanisms predisposing frail patients to a higher risk of infectious or inflammatory events...
March 16, 2018: Digestive and Liver Disease
https://www.readbyqxmd.com/read/29626394/microbiome-and-health-ramifications-of-intelligent-deception
#14
George B Stefano, Rachel Fine, Richard M Kream
Ten thousand years ago, the foundation for agricultural development and animal domestication was laid. Neolithic founder crops were carbohydrate-laden cereal grasses that facilitated transformation of hunter-gather societies into ancient civilizations with realistic capabilities for population expansion. In the last 3-4 decades, however, debilitating medical consequences of a progressively narrowed high caloric diet incorporating processed carbohydrates, animal protein, saturated fat and cholesterol, are translated into a global epidemic of obesity linked to metabolic and endocrine disorders, which, in part, emerged from the enhancement of our longevity...
April 7, 2018: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29624860/hepatic-encephalopathy-diagnosis-and-management
#15
Piero Amodio
Hepatic encephalopathy (HE) is a peculiar kind of brain dysfunction caused by liver insufficiency and/or portal-systemic shunting. It is related to gut-derived substances. It is a relevant cause of morbidity and hospitalisation for patients with cirrhosis. The prognosis of HE is important in terms of survival and re-hospitalisation. It is related to impaired quality of life, falls and poor driving, presents a relevant burden for caregivers and health services, and may negatively impacts on patient's job and income...
April 6, 2018: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/29624599/a-snapshot-of-gut-microbiota-of-an-adult-urban-population-from-western-region-of-india
#16
Disha Tandon, Mohammed Monzoorul Haque, Saravanan R, Shafiq Shaikh, Sriram P, Ashok Kumar Dubey, Sharmila S Mande
The human gut microbiome contributes to a broad range of biochemical and metabolic functions that directly or indirectly affect human physiology. Several recent studies have indicated that factors like age, geographical location, genetic makeup, and individual health status significantly influence the diversity, stability, and resilience of the gut microbiome. Of the mentioned factors, geographical location (and related dietary/socio-economic context) appears to explain a significant portion of microbiome variation observed in various previously conducted base-line studies on human gut microbiome...
2018: PloS One
https://www.readbyqxmd.com/read/29623708/-gut-microbiota-its-development-and-relation-to-certain-diseases
#17
Hana Kiňová Sepová, Boris Dudík, Andrea Bilková
Coexistence of humans with microorganisms is well known for a long time. Besides the association with infectious diseases, personal microbiota is important for human health, possibly for some non-infectious diseases. Colonization of the human body with appropriate microorganisms after delivery is essential for physiological immune system maturation and also has an influence on central nervous system development. The composition of the gut microbiota is affected by the mode of delivery, early life nutrition and last but not least by lifestyle and drug, especially antibiotics intake...
2018: Ceská a Slovenská Farmacie
https://www.readbyqxmd.com/read/29623674/current-state-of-knowledge-on-implications-of-gut-microbiome-for-surgical-conditions
#18
Edmund B Chen, Cori Cason, Jack A Gilbert, Karen J Ho
The role of the microbiome in human health has become a central tenant of current medical research, infiltrating a diverse disciplinary base whereby microbiology, computer science, ecology, gastroenterology, immunology, neurophysiology and psychology, metabolism, and cardiovascular medicine all intersect. Traditionally, commensal gut microbiota have been assumed to play a significant role only in the metabolic processing of dietary nutrients and host metabolites, the fortification of gut epithelial barrier function, and the development of mucosal immunity...
April 5, 2018: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/29621737/time-for-food-the-impact-of-diet-on-gut-microbiota-and-human-health
#19
REVIEW
Na Zhang, Zhongjie Ju, Tao Zuo
There is growing recognition of the role of diet on modulating the composition and metabolic activity of the human gut microbiota, which in turn influence health. Dietary ingredients and food additives have a substantial impact on the gut microbiota and hence affect human health. Updates on current understanding of the gut microbiota in diseases and metabolic disorders are addressed in this review, providing insights into how this can be transferred from bench to bench side as gut microbes are integrated with food...
February 5, 2018: Nutrition
https://www.readbyqxmd.com/read/29621590/vancomycin-resistance-in-enterococcus-faecium-isolated-from-danish-chicken-meat-is-located-on-a-pvef4-like-plasmid-persisting-in-poultry-for-18-years
#20
Helena Leinweber, Sulaiman M I Alotaibi, Søren Overballe-Petersen, Frank Hansen, Henrik Hasman, Valeria Bortolaia, Anette M Hammerum, Hanne Ingmer
The occurrence of vancomycin-resistant Enterococcus faecium (VREfm) in food has public health relevance since foodborne VREfm may colonize the gut of consumers and transfer vancomycin resistance genes to the indigenous gut microbiota. Therefore, we determined occurrence and elucidated genetic traits of VREfm in Danish retail chicken meat. Three out of 40 samples (7.5%) from two slaughterhouses yielded VREfm (vancomycin MIC > 32mg/L). This is the first report of VREfm in Danish retail poultry meat since 2010 (DANMAP)...
April 2, 2018: International Journal of Antimicrobial Agents
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