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https://www.readbyqxmd.com/read/28636896/early-maladaptive-schemas-of-emotional-deprivation-social-isolation-shame-and-abandonment-are-related-to-a-history-of-suicide-attempts-among-patients-with-major-depressive-disorders
#1
Mohammad Ahmadpanah, Sommayyeh Astinsadaf, Amineh Akhondi, Mohammad Haghighi, Dena Sadeghi Bahmani, Marzieh Nazaribadie, Leila Jahangard, Edith Holsboer-Trachsler, Serge Brand
BACKGROUND: Patients with psychiatric disorders have an exceptionally high risk of completed or attempted suicide. This holds particularly true for patients with major depressive disorders. The aim of the present study was to explore whether patients with major depressive disorders (MDD) and a history of suicide attempts differed in their early maladaptive schemas from patients with MDD but without such a history or from healthy controls. METHOD: Ninety participants took part in the study...
June 18, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28634156/classifying-chinese-questions-related-to-health-care-posted-by-consumers-via-the-internet
#2
Haihong Guo, Xu Na, Li Hou, Jiao Li
BACKGROUND: In question answering (QA) system development, question classification is crucial for identifying information needs and improving the accuracy of returned answers. Although the questions are domain-specific, they are asked by non-professionals, making the question classification task more challenging. OBJECTIVE: This study aimed to classify health care-related questions posted by the general public (Chinese speakers) on the Internet. METHODS: A topic-based classification schema for health-related questions was built by manually annotating randomly selected questions...
June 20, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28632751/owl2-benchmarking-for-the-evaluation-of-knowledge-based-systems
#3
Sher Afgun Khan, Muhammad Abdul Qadir, Muhammad Azeem Abbas, Muhammad Tanvir Afzal
OWL2 semantics are becoming increasingly popular for the real domain applications like Gene engineering and health MIS. The present work identifies the research gap that negligible attention has been paid to the performance evaluation of Knowledge Base Systems (KBS) using OWL2 semantics. To fulfil this identified research gap, an OWL2 benchmark for the evaluation of KBS is proposed. The proposed benchmark addresses the foundational blocks of an ontology benchmark i.e. data schema, workload and performance metrics...
2017: PloS One
https://www.readbyqxmd.com/read/28628549/a-classification-system-to-guide-physical-therapy-management-in-huntington-disease-a-case-series
#4
Nora E Fritz, Monica Busse, Karen Jones, Hanan Khalil, Lori Quinn
BACKGROUND AND PURPOSE: Individuals with Huntington disease (HD), a rare neurological disease, experience impairments in mobility and cognition throughout their disease course. The Medical Research Council framework provides a schema that can be applied to the development and evaluation of complex interventions, such as those provided by physical therapists. Treatment-based classifications, based on expert consensus and available literature, are helpful in guiding physical therapy management across the stages of HD...
July 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28625707/-algorithms-based-on-medico-administrative-data-in-the-field-of-endocrine-nutritional-and-metabolic-diseases-especially-diabetes
#5
S Fosse-Edorh, A Rigou, S Morin, L Fezeu, L Mandereau-Bruno, A Fagot-Campagna
BACKGROUND: Medico-administrative databases represent a very interesting source of information in the field of endocrine, nutritional and metabolic diseases. The objective of this article is to describe the early works of the Redsiam working group in this field. METHODS: Algorithms developed in France in the field of diabetes, the treatment of dyslipidemia, precocious puberty, and bariatric surgery based on the National Inter-schema Information System on Health Insurance (SNIIRAM) data were identified and described...
June 15, 2017: Revue D'épidémiologie et de Santé Publique
https://www.readbyqxmd.com/read/28625189/influence-of-early-maladaptive-schemas-depression-and-anxiety-on-the-intensity-of-self-reported-cognitive-complaint-in-older-adults-with-subjective-cognitive-decline
#6
Caroline Tandetnik, Thierry Hergueta, Philippe Bonnet, Bruno Dubois, Catherine Bungener
BACKGROUND: Subjective cognitive decline (SCD) designates a self-reported cognitive decline despite preserved cognitive abilities. This study aims to explore, in older adults with SCD, the association between intensity of self-reported cognitive complaint and psychological factors including Young's early maladaptive schemas (EMSs) (i.e. enduring cognitive structures giving rise to beliefs about oneself and the world), as well as depression and anxiety. METHODS: Seventy-six subjects (69...
June 19, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28623588/design-of-knowledge-bases-for-plant-gene-regulatory-networks
#7
Eric Mukundi, Fabio Gomez-Cano, Wilberforce Zachary Ouma, Erich Grotewold
Developing a knowledge base that contains all the information necessary for the researcher studying gene regulation in a particular organism can be accomplished in four stages. This begins with defining the data scope. We describe here the necessary information and resources, and outline the methods for obtaining data. The second stage consists of designing the schema, which involves defining the entire arrangement of the database in a systematic plan. The third stage is the implementation, defined by actualization of the database by using software according to a predefined schema...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28619103/effects-of-muscle-dysmorphia-social-comparisons-and-body-schema-priming-on-desire-for-social-interaction-an-experimental-approach
#8
Catharina Schneider, Maria Agthe, Takuya Yanagida, Martin Voracek, Kristina Hennig-Fast
BACKGROUND: Muscle dysmorphia (MD) is a relatively young diagnosis referring to the desire for a high degree in lean muscle mass, while simultaneously believing that one is insufficiently muscular, mostly found in men. It goes along with a risk for social withdrawal to maintain rigid exercise and dietary regimen. The aim of the current study was thus, to explore differences in men with and without a risk for muscle dysmorphia regarding their desire for social interaction. Furthermore, we investigated potential effects of individual social comparison tendencies (the tendency to compare oneself with persons who are perceived to be superior or inferior to oneself on a certain dimension) and of one's own body schema on the desire for social interaction...
June 15, 2017: BMC Psychology
https://www.readbyqxmd.com/read/28611719/hablo-ingl%C3%A3-s-y-espa%C3%A3-ol-cultural-self-schemas-as-a-function-of-language
#9
Gloriana Rodríguez-Arauz, Nairán Ramírez-Esparza, Norma Pérez-Brena, Ryan L Boyd
Research has demonstrated that bilingual individuals experience a "double personality," which allows them to shift their self-schemas when they are primed with different language modes. In this study, we examine whether self-schemas change in Mexican-American (N = 193) bilinguals living in the U.S. when they provide open-ended personality self-descriptions in both English and Spanish. We used the Meaning Extraction Helper (MEH) software to extract the most salient self-schemas that influence individuals' self-defining process...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28605772/annosys-implementation-of-a-generic-annotation-system-for-schema-based-data-using-the-example-of-biodiversity-collection-data
#10
L Suhrbier, W-H Kusber, O Tschöpe, A Güntsch, W G Berendsohn
No abstract text is available yet for this article.
January 1, 2017: Database: the Journal of Biological Databases and Curation
https://www.readbyqxmd.com/read/28604432/self-perceived-viral-load-and-sexual-risk-behavior-among-known-hiv-positive-msm-in-san-francisco-2014
#11
John Guigayoma, Yea-Hung Chen, Jonathan M Snowden, Glenn-Milo Santos, Jennifer Hecht, H Fisher Raymond
BACKGROUND: Self-perceived viral suppression status among men who have sex with men (MSM) may impact HIV risk transmission behaviors. METHODS: We conducted a 2014 cross-sectional survey of MSM in San Francisco and assessed differences in sexual risk behavior among known HIV-positive MSM based on viral suppression of HIV. We collected demographics, self-perceived viral load status, and sexual risk behavior and tested for viral load levels through laboratory assays...
July 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28604277/validation-of-schema-coping-inventory-and-schema-mode-inventory-in-adolescents
#12
Marjolein F van Wijk-Herbrink, Jeffrey Roelofs, Nick J Broers, Marleen M Rijkeboer, Arnoud Arntz, David P Bernstein
This study investigated whether the schema therapy constructs of schema coping and schema modes have validity in adolescents. We examined the validity and reliability of the Schema Coping Inventory (SCI) and an 80-item version of the Schema Mode Inventory (SMI) in a mixed sample of adolescents. Confirmatory factor analyses showed that the first-order factor structures of the SCI and SMI were replicated, but that the hypothesized higher-order models of the SMI were not confirmed. Instead, we proposed an alternative higher-order model of Internalizing, Externalizing, Overachieving, and Healthy modes...
June 12, 2017: Journal of Personality Disorders
https://www.readbyqxmd.com/read/28601178/pediatric-hepatobiliary-neoplasms-an-overview-and-update
#13
REVIEW
Ali Yikilmaz, Michael George, Edward Y Lee
Recent developments regarding the treatment of pediatric liver tumors have significantly improved patient care. Stimulated by collaboration between international pediatric groups, advances have been made in surgical techniques, transplantation options, and chemotherapy schemas. In light of this progress, clear understanding of the state-of-the-art imaging evaluation of hepatobiliary tumors has become even more integral to the effective management of children with hepatic neoplasms. The unique imaging features of hepatic neoplasms in the pediatric population, when coupled with supportive demographic data and laboratory findings, can lead to accurate diagnosis and proper treatment of hepatobiliary tumors...
July 2017: Radiologic Clinics of North America
https://www.readbyqxmd.com/read/28599887/phase-i-trial-of-cediranib-in-combination-with-cisplatin-and-pemetrexed-in-chemo-naive-patients-with-unresectable-malignant-pleural-mesothelioma-swog-s0905
#14
Anne S Tsao, James Moon, Ignacio I Wistuba, Nicholas J Vogelzang, Gregory P Kalemkerian, Mary W Redman, David R Gandara, Karen Kelly
BACKGROUND: In malignant pleural mesothelioma (MPM), targeting angiogenesis, with cediranib, a vascular endothelial growth factor receptor (VEGFR) and platelet derived growth factor receptor (PDGFR) inhibitor, may have therapeutic potential. METHODS: S0905 phase I combined cediranib (2 dose cohorts 30 mg and 20 mg daily) with cisplatin-pemetrexed for 6 cycles followed by maintenance cediranib in unresectable chemo-naïve MPM patients of any histologic subtype. The primary endpoint established the MTD in combination with cisplatin-pemetrexed in a dose de-escalation schema...
June 6, 2017: Journal of Thoracic Oncology
https://www.readbyqxmd.com/read/28594284/evidence-based-medicine-and-contemporary-certification-analysis-of-the-american-board-of-vascular-medicine-endovascular-board-examination
#15
David Paul Slovut, Bruce H Gray, Amin Saiar, Mark C Bates
Since 2005, the American Board of Vascular Medicine (ABVM) endovascular examination has been used to certify vascular practitioners. Annual rigorous review has confirmed it is psychometrically valid and reliable. However, the evidence basis underlying the examination items has not been studied systematically. The aim of this study was to adjudicate class of recommendation (COR) and level of evidence (LOE) for the 2015 ABVM endovascular examination and establish an additional feedback mechanism for examination improvement based on contemporary evidence-based guidelines...
June 1, 2017: Vascular Medicine
https://www.readbyqxmd.com/read/28593861/challenges-behind-proving-efficacy-of-adjuvant-chemotherapy-after-preoperative-chemoradiation-for-rectal-cancer
#16
REVIEW
Carlos Carvalho, Rob Glynne-Jones
For patients with high-risk stage II or stage III colon cancer, adjuvant chemotherapy with fluoropyrimidine monotherapy reduces the risk of recurrence and death by approximately 20-30%. Additional improvements have been reported in three phase 3 colon cancer trials when oxaliplatin was added to the chemoradiation regimen, although the effect was mainly on disease-free survival. However, patients with rectal cancer were specifically excluded from these landmark studies because of potential toxicity and the confounding impact of radiotherapy and chemoradiation...
June 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28592975/prognostic-factors-and-treatment-of-pediatric-acute-lymphoblastic-leukemia
#17
REVIEW
Jae Wook Lee, Bin Cho
The event-free survival (EFS) for pediatric acute lymphoblastic leukemia (ALL) has shown remarkable improvement in the past several decades. In Korea also, a recent study showed 10-year EFS of 78.5%. Much of the improved outcome for pediatric ALL stems from the accurate identification of prognostic factors, the designation of risk group based on these factors, and treatment of appropriate duration and intensity according to risk group, done within the setting of cooperative clinical trials. The schema of first-line therapy for ALL remains mostly unchanged, although many groups have now reported on the elimination of cranial irradiation in all patients with low rates of central nervous system relapse...
May 2017: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/28586264/practical-considerations-for-chimeric-antigen-receptor-design-and-delivery
#18
Robyn A A Oldham, Jeffrey A Medin
The development of chimeric antigen receptor (CAR)-modified immune cells has become a highly active field of research since the introduction of this approach in 1989. New ideas are constantly being proposed and tested, resulting in CARs that are more effective and specialized. Areas covered: Many aspects of CAR design and administration can be varied in order to achieve the best possible outcomes; optimization of this therapeutic schema is an active area of research. Here, the authors summarize the work that has been carried out thus far to assess different adaptations for each portion of the CAR itself...
June 16, 2017: Expert Opinion on Biological Therapy
https://www.readbyqxmd.com/read/28585923/dats-the-data-tag-suite-to-enable-discoverability-of-datasets
#19
Susanna-Assunta Sansone, Alejandra Gonzalez-Beltran, Philippe Rocca-Serra, George Alter, Jeffrey S Grethe, Hua Xu, Ian M Fore, Jared Lyle, Anupama E Gururaj, Xiaoling Chen, Hyeon-Eui Kim, Nansu Zong, Yueling Li, Ruiling Liu, I Burak Ozyurt, Lucila Ohno-Machado
Today's science increasingly requires effective ways to find and access existing datasets that are distributed across a range of repositories. For researchers in the life sciences, discoverability of datasets may soon become as essential as identifying the latest publications via PubMed. Through an international collaborative effort funded by the National Institutes of Health (NIH)'s Big Data to Knowledge (BD2K) initiative, we have designed and implemented the DAta Tag Suite (DATS) model to support the DataMed data discovery index...
June 6, 2017: Scientific Data
https://www.readbyqxmd.com/read/28580134/what-is-open-peer-review-a-systematic-review
#20
Tony Ross-Hellauer
BACKGROUND:  "Open peer review" (OPR), despite being a major pillar of Open Science, has neither a standardized definition nor an agreed schema of its features and implementations. The literature reflects this, with a myriad of overlapping and often contradictory definitions. While the term is used by some to refer to peer review where the identities of both author and reviewer are disclosed to each other, for others it signifies systems where reviewer reports are published alongside articles...
2017: F1000Research
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