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https://www.readbyqxmd.com/read/28091817/teratomas-of-the-cranial-vault-a-systematic-analysis-of-clinical-outcomes-stratified-by-histopathological-subtypes
#1
Carlito Lagman, Timothy T Bui, Brittany L Voth, Lawrance K Chung, David J Seo, Courtney Duong, Mark R Libowitz, Naomi E Walker, Daniel T Nagasawa, Isaac Yang
BACKGROUND: Teratomas of the cranial vault are divided into histopathological subtypes and grouped by prognoses: mature (good prognosis), mixed/malignant and immature teratomas (intermediate prognosis). This schema also includes non-teratomatous tumors. The authors of this study sought to elucidate histologically dependent predictors of survival and further clarify the classification system of intracranial teratomas. METHODS: We performed a systematic analysis of the published literature to identify studies describing patients with intracranial teratomas diagnosed with magnetic resonance imaging (MRI) and presenting definite information on histologies, therapies, and outcomes at a minimum follow-up of 2 years...
January 14, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28088330/genomic-insights-in-gynecologic-cancer
#2
Erika Roddy, Jocelyn Chapman
Recent technological advances in DNA sequencing have enabled a remarkably detailed understanding of the molecular changes that define gynecologic and other cancers. Several groups have carried out large-scale genomic analyses of ovarian, uterine, and most recently, cervical cancer. These analyses have led to new insights into the molecular changes characterizing these cancers, which provide insight into clinical outcomes. These molecular characterizations have similarly led to new genomic-based classification schemas, which may better stratify clinical outcomes, help prognosticate and guide treatments...
November 11, 2016: Current Problems in Cancer
https://www.readbyqxmd.com/read/28080438/maladaptive-schemas-mediate-poor-parental-attachment-and-suicidality-in-college-students
#3
Jennifer Langhinrichsen-Rohling, Kali Thompson, Candice Selwyn, Heather Finnegan, Tiffany Misra
In college-aged adults (n = 766), the transition to adulthood may aggravate risk factors for suicidal behavior such as poor parental attachment and maladaptive self-schemas. Since poor parental attachment may facilitate developing maladaptive self-related schemas, this study was designed to determine whether specific maladaptive schemas mediate the relation between poor parental attachment and college students' suicide proneness and ideation. Findings supported this hypothesis. Defectiveness and emotional deprivation schemas, which are consistent with "perceived burdensomeness" and "thwarted belonging" (Joiner, 2005 ), may be important intervention targets for suicide prevention programs...
January 12, 2017: Death Studies
https://www.readbyqxmd.com/read/28077709/semantic-congruence-accelerates-the-onset-of-the-neural-signals-of-successful-memory-encoding
#4
Pau A Packard, Antoni Rodríguez-Fornells, Nico Bunzeck, Berta Nicolás, Ruth de Diego-Balaguer, Lluís Fuentemilla
: As the stream of experience unfolds, our memory system rapidly transforms current inputs into long-lasting meaningful memories. A putative neural mechanism that strongly influences how input elements are transformed into meaningful memory codes relies on the ability to integrate them with existing structures of knowledge or schemas. However, it is not yet clear whether schema-related integration neural mechanisms occur during online encoding. In the current investigation, we examined the encoding-dependent nature of this phenomenon in humans...
January 11, 2017: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/28077329/body-schema-plasticity-after-stroke-subjective-and-neurophysiological-correlates-of-the-rubber-hand-illusion
#5
Roberto Llorens, Adrián Borrego, Priscila Palomo, Ausiàs Cebolla, Enrique Noé, Sergi Bermúdez I Badia, Rosa Baños
Stroke can lead to motor impairments that can affect the body structure and restraint mobility. We hypothesize that brain lesions and their motor sequelae can distort the body schema, a sensorimotor map of body parts and elements in the peripersonal space through which human beings embody the reachable space and ready the body for forthcoming movements. Two main constructs have been identified in the embodiment mechanism: body-ownership, the sense that the body that one inhabits is his/her own, and agency, the sense that one can move and control his/her body...
January 8, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/28073044/influence-of-the-body-schema-on-mirror-touch-synesthesia
#6
Jared Medina, Carrie DePasquale
Individuals with mirror-touch synesthesia (MTS) report feeling touch on their own body when seeing someone else being touched. We examined how the body schema - an on-line representation of body position in space - is involved in mapping touch from a viewed body to one's own body. We showed 45 mirror-touch synesthetes videos of a hand being touched, varying the location of the viewed touch by hand (left, right), skin surface (palmar, dorsal) and finger (index, ring). Participant hand posture was either congruent or incongruent with the posture of the viewed hand...
December 24, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28068640/transient-medial-prefrontal-perturbation-reduces-false-memory-formation
#7
Ruud M W J Berkers, Marieke van der Linden, Rafael F de Almeida, Nils C J Müller, Leonore Bovy, Martin Dresler, Richard G M Morris, Guillén Fernández
Knowledge extracted across previous experiences, or schemas, benefit encoding and retention of congruent information. However, they can also reduce specificity and augment memory for semantically related, but false information. A demonstration of the latter is given by the Deese-Roediger-McDermott (DRM) paradigm, where the studying of words that fit a common semantic schema are found to induce false memories for words that are congruent with the given schema, but were not studied. The medial prefrontal cortex (mPFC) has been ascribed the function of leveraging prior knowledge to influence encoding and retrieval, based on imaging and patient studies...
December 24, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/28063545/pr%C3%A3-vention-de-l-infection-n%C3%A3-onatale-%C3%A3-streptocoques-du-groupe-b-d-apparition-pr%C3%A3-coce
#8
Deborah Money, Victoria M Allen
OBJECTIF: Analyser les données issues de la littérature et formuler des recommandations sur la prise en charge des parturientes en vue de prévenir l'infection néonatale à streptocoques du groupe B d'apparition précoce. Parmi les révisions clés que renferme la présente directive clinique mise à jour, on trouve des modifications quant aux recommandations en ce qui concerne les schémas posologiques d'antibioprophylaxie, les épreuves de sensibilité et la prise en charge des femmes présentant une rupture prématurée des membranes...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28061931/synergistic-effect-of-hormones-and-biosolids-on-scenedesmus-abundans-for-eliciting-total-biolipids
#9
Chelladurai Chellamboli, Muthiah Perumalsamy
  This study states an integrated approach to grow Scenedesmus abundans in the presence of biostimulants as a robust flourishing organism pertaining to attain the maximum yield of the biodiesel through transesterification. These assessments are especially targeted to achieve the appreciable profit on biodiesel using three biostimulants such as, Indole 3-acetic acid (3 IAA), 6-Benzylaminopurine (6 BAP), and Gibberellic acid (GA) hormones. The proposed schema proved a rise in biomass; as well as lipid content, compared with an alga grown in the absence of hormones...
December 1, 2016: Water Environment Research: a Research Publication of the Water Environment Federation
https://www.readbyqxmd.com/read/28059574/the-activation-of-incompetence-schemas-in-response-to-negative-sexual-events-in-heterosexual-and-lesbian-women-the-moderator-role-of-personality-traits-and-dysfunctional-sexual-beliefs
#10
Maria Manuela Peixoto, Pedro Nobre
Personality traits and dysfunctional sexual beliefs have been described as vulnerability factors for sexual dysfunction in women, and have also been proposed as dispositional variables for the activation of incompetence schemas in response to negative sexual events. However, no study has tested the role of personality traits and dysfunctional sexual beliefs in the activation of incompetence schemas. The current study aimed to assess the moderator role of neuroticism, extraversion, and dysfunctional sexual beliefs in the association between frequency of unsuccessful sexual episodes and activation of incompetence schemas in heterosexual and lesbian women...
January 6, 2017: Journal of Sex Research
https://www.readbyqxmd.com/read/28051899/serious-games-for-health-the-potential-of-metadata
#11
Stefan Göbel, Ralph Maddison
OBJECTIVE: Numerous serious games and health games exist, either as commercial products (typically with a focus on entertaining a broad user group) or smaller games and game prototypes, often resulting from research projects (typically tailored to a smaller user group with a specific health characteristic). A major drawback of existing health games is that they are not very well described and attributed with (machine-readable, quantitative, and qualitative) metadata such as the characterizing goal of the game, the target user group, or expected health effects well proven in scientific studies...
January 4, 2017: Games for Health
https://www.readbyqxmd.com/read/28051888/the-benefits-and-burdens-of-cancer-a-prospective-longitudinal-cohort-study-of-adolescents-and-young-adults
#12
Joelle P Straehla, Krysta S Barton, Joyce P Yi-Frazier, Claire Wharton, Kevin Scott Baker, Kira Bona, Joanne Wolfe, Abby R Rosenberg
BACKGROUND: Adolescents and early young adults (AYAs) with cancer are at high risk for poor outcomes. Positive psychological responses such as benefit-finding may buffer the negative impacts of cancer but are poorly understood in this population. OBJECTIVE: We aimed to prospectively describe the content and trajectory of benefit- and burden-finding among AYAs to develop potential targets for future intervention. PATIENTS AND METHODS: One-on-one semistructured interviews were conducted with English-speaking AYA patients (aged 14-25 years) within 60 days of diagnosis of a noncentral nervous system malignancy requiring chemotherapy, 6-12 and 12-18 months later...
January 4, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28050150/risk-stratification-treatment-selection-and-transplant-eligibility-in-multiple-myeloma-a-qualitative-study-of-the-perspectives-and-self-reported-practices-of-oncologists
#13
T W LeBlanc, A Howson, W Turell, P Sheldon, S C Locke, S A Tuchman, C Gasparetto, S Kaura, Z M Khan, A P Abernethy
BACKGROUND: Since the early 2000s, treatment options for multiple myeloma have rapidly expanded, adding significant complexity to the management of this disease. To our knowledge, no systematic qualitative research on clinical decision-making in multiple myeloma has been published. We sought to characterize how physicians view and implement guidelines and incorporate novel approaches into patient care. METHODS: We designed a semi-structured qualitative interview guide informed by literature review and an expert advisory panel...
December 2016: Current Oncology
https://www.readbyqxmd.com/read/28048872/we-fg-bra-10-radiodosimetry-of-a-novel-alpha-particle-therapy-targeted-to-uveal-melanoma-absorbed-dose-to-organs-in-mice
#14
Christopher J Tichacek, Narges K Tafreshi, Mikalai M Budzevich, Epifanio Ruiz, Thaddeus J Wadas, Mark L McLaughlin, Eduardo G Moros, David L Morse
PURPOSE: The melanocortin-1 receptor (MC1R) is expressed in 94% of uveal melanomas and is described as an ideal target for this untreatable disease. MC1RL is a high affinity MC1R specific peptidomimetic ligand that can serve as a scaffold for therapeutic conjugates such as alpha particle emitting isotopes. The purpose of this study was to assess normal tissue distribution and risk as a result of using the DOTA chelator conjugated to MC1RL to deliver (225) Ac: MC1RL-DOTA-(225) Ac. METHODS: 17 non-tumor bearing BALB/c mice were intravenously injected with the novel MC1RL-DOTA-(225) Ac radiopharmaceutical with an average initial administered activity of 2...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047270/su-f-t-231-improving-the-efficiency-of-a-radiotherapy-peer-review-system-for-quality-assurance
#15
S Hsu, A Basavatia, M Garg, S Kalnicki, W Tome
PURPOSE: To improve the efficiency of a radiotherapy peer-review system using a commercially available software application for plan quality evaluation and documentation. METHODS: A commercial application, FullAccess (Radialogica LLC, Version 1.4.4), was implemented in a Citrix platform for peer-review process and patient documentation. This application can display images, isodose lines, and dose-volume histograms and create plan reports for peer-review process...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044012/modelling-auditory-attention
#16
REVIEW
Emine Merve Kaya, Mounya Elhilali
Sounds in everyday life seldom appear in isolation. Both humans and machines are constantly flooded with a cacophony of sounds that need to be sorted through and scoured for relevant information-a phenomenon referred to as the 'cocktail party problem'. A key component in parsing acoustic scenes is the role of attention, which mediates perception and behaviour by focusing both sensory and cognitive resources on pertinent information in the stimulus space. The current article provides a review of modelling studies of auditory attention...
February 19, 2017: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28039821/selecting-the-best-aop-for-isoxazolyl-penicillins-degradation-as-a-function-of-water-characteristics-effects-of-ph-chemical-nature-of-additives-and-pollutant-concentration
#17
Paola Villegas-Guzman, Javier Silva-Agredo, Oscar Florez, Ana L Giraldo-Aguirre, Cesar Pulgarin, Ricardo A Torres-Palma
To provide new insights toward the selection of the most suitable AOP for isoxazolyl penicillins elimination, the degradation of dicloxacillin, a isoxazolyl penicillin model, was studied using different advanced oxidation processes (AOPs): ultrasound (US), photo-Fenton (UV/H2O2/Fe(2+)) and TiO2 photocatalysis (UV/TiO2). Although all processes achieved total removal of the antibiotic and antimicrobial activity, and increased the biodegradability level of the solutions, significant differences concerning the mineralization extend, the pH of the solution, the pollutant concentration and the chemical nature of additives were found...
December 28, 2016: Journal of Environmental Management
https://www.readbyqxmd.com/read/28035734/does-schema-therapy-change-schemas-and-symptoms-a-systematic-review-across-mental-health-disorders
#18
REVIEW
Christopher D J Taylor, Penny Bee, Gillian Haddock
PURPOSE: Schema therapy was first applied to individuals with borderline personality disorder (BPD) over 20 years ago, and more recent work has suggested efficacy across a range of disorders. The present review aimed to systematically synthesize evidence for the efficacy and effectiveness of schema therapy in reducing early maladaptive schema (EMS) and improving symptoms as applied to a range of mental health disorders in adults including BPD, other personality disorders, eating disorders, anxiety disorders, and post-traumatic stress disorder...
December 30, 2016: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28031342/transcriptional-classification-and-functional-characterization-of-human-airway-macrophage-and-dendritic-cell-subsets
#19
Vineet I Patel, J Leland Booth, Elizabeth S Duggan, Steven Cate, Vicky L White, David Hutchings, Susan Kovats, Dennis M Burian, Mikhail Dozmorov, Jordan P Metcalf
The respiratory system is a complex network of many cell types, including subsets of macrophages and dendritic cells that work together to maintain steady-state respiration. Owing to limitations in acquiring cells from healthy human lung, these subsets remain poorly characterized transcriptionally and phenotypically. We set out to systematically identify these subsets in human airways by developing a schema of isolating large numbers of cells by whole-lung bronchoalveolar lavage. Six subsets of phagocytic APC (HLA-DR(+)) were consistently observed...
December 28, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28026781/exploring-consensus-rna-substructural-patterns-using-subgraph-mining
#20
Qingfeng Chen, Chaowang Lan, Baoshan Chen, Lusheng Wang, Jinyan Li, Chengqi Zhang
Frequently recurring RNA structural motifs play important roles in RNA folding process and interaction with other molecules. Traditional index-based and shape-based schemas are useful in modeling RNA secondary structures but ignore the structural discrepancy of individual RNA family member. Further, the in-depth analysis of underlying substructure pattern is insufficient due to varied and unnormalized substructure data. This prevents us from understanding RNAs functions and their inherent synergistic regulation networks...
December 26, 2016: IEEE/ACM Transactions on Computational Biology and Bioinformatics
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