keyword
MENU ▼
Read by QxMD icon Read
search

Single

keyword
https://www.readbyqxmd.com/read/28239980/rational-design-of-mini-size-carbon-nitride-nanosheets-with-double-excitation-and-ph-dependent-fluorescence-behaviors-for-two-photon-cell-imaging
#1
Liu Jinhua, DuoDuo Zhao, Lin Li, Minrui Weng, Chengwu Zhang, Shiyu Zhang, Jixin Zhu, Yong Feng, Kaimin Shih, Wei Huang
Synthesis of mini-size carbon nitride nanosheets (CNNSs) by using traditional ultrasonic method still remains a great challenge. Herein, Size-tunable and uniform mini-size CNNSs are synthesized by hydrothermal carbonization of the single polyethyleneimine (PEI) precursor.The as-obtained mini-size CNNSs possesses uniform size, good hydrophilicity, abundant nitrogen active sites, and not only exhibit double excitation- and pH-depending fluorescence behaviors, but two-photon exitation fluorescence. The resulting CNNSs display relatively low toxicity and can be efficiently delivered into live cells for two-photon fluorescence image, further confirm that the obtained CNNSs can potentially be used as fluorescence probes in biochemical applications...
February 26, 2017: Chemistry, An Asian Journal
https://www.readbyqxmd.com/read/28239979/beyond-sodium-phosphate-and-potassium-potential-dietary-interventions-in-kidney-disease
#2
EDITORIAL
Jaimon T Kelly, Megan Rossi, David W Johnson, Katrina L Campbell
People with kidney disease are advised to restrict individual nutrients, such as sodium, potassium, and phosphate, in line with current best practice guidelines. However, there is limited evidence to support the efficacy of single nutrient strategies, and compliance remains a challenge for clinicians to overcome. Many factors contribute to poor compliance with dietary prescriptions, including conflicting priorities for single nutrient restriction, the arduous self-monitoring required, and the health-related knock-on effects resulting from targeting these nutrients in isolation...
February 26, 2017: Seminars in Dialysis
https://www.readbyqxmd.com/read/28239956/spreading-of-thelazia-callipaeda-in-greece
#3
E Papadopoulos, A Komnenou, A Thomas, E Ioannidou, V Colella, D Otranto
Thelazia callipaeda (Spirurida, Thelaziidae), the so-called oriental eyeworm, has been increasingly reported as an agent of infection in animals and humans from many European countries. Clinical signs range from subclinical to moderate or severe ocular disorders (e.g., epiphora, photophobia, conjunctivitis, keratitis, ulcers). The disease has been also diagnosed in animals from countries of the Balkan area (e.g., Croatia, Bosnia and Herzegovina and Serbia), but only a single case of canine thelaziosis, presumably autochthonous, was reported in Northern Greece...
February 26, 2017: Transboundary and Emerging Diseases
https://www.readbyqxmd.com/read/28239919/large-multicentre-pilot-randomised-controlled-trial-testing-a-low-cost-tailored-self-help-smoking-cessation-text-message-intervention-for-pregnant-smokers-miquit
#4
Felix Naughton, Sue Cooper, Katharine Foster, Joanne Emery, Jo Leonardi-Bee, Stephen Sutton, Matthew Jones, Michael Ussher, Rachel Whitemore, Matthew Leighton, Alan Montgomery, Steve Parrott, Tim Coleman
AIMS: To estimate the effectiveness of pregnancy smoking cessation support delivered by SMS text message and key parameters needed to plan a definitive trial. DESIGN: Multicentre, parallel-group, single-blinded, individual randomised controlled trial SETTING: 16 antenatal clinics in England. PARTICIPANTS: 407 participants were randomised to the intervention (n = 203) or usual care (n = 204). Eligible women were <25 weeks gestation, smoked at least 1 daily cigarette (>5 pre-pregnancy), were able to receive and understand English SMS texts and were not already using text-based cessation support...
February 26, 2017: Addiction
https://www.readbyqxmd.com/read/28239907/effects-of-oral-%C3%AE-lipoic-acid-administration-on-body-weight-in-overweight-or-obese-subjects-a-crossover-randomized-double-blind-placebo-controlled-trial
#5
Nong Li, Weili Yan, Xiaojuan Hu, Yongdi Huang, Fugang Wang, Weiguo Zhang, Qian Wang, Xiaoling Wang, Kehong Sun
OBJECTIVE: Alpha-lipoic acid (ALA) has shown beneficial properties on diabetes and obesity. The aim of this study was to examine the effects of oral ALA on body weight in subjects with overweight or obese. DESIGN: Single-centre, randomized, double-blind, crossover controlled study. PARTICIPANTS: A total of 166 subjects of Chinese Han ethnicity with a BMI ≥25 kg/m(2) were screened and 103 subjects fulfilled the study requirements, in terms of informed consent and participation to the study...
January 12, 2017: Clinical Endocrinology
https://www.readbyqxmd.com/read/28239899/correlation-estimation-with-singly-truncated-bivariate-data
#6
Jongho Im, Eunyong Ahn, Namseon Beck, Jae Kwang Kim, Taesung Park
Correlation coefficient estimates are often attenuated for truncated samples in the sense that the estimates are biased towards zero. Motivated by real data collected in South Sudan, we consider correlation coefficient estimation with singly truncated bivariate data. By considering a linear regression model in which a truncated variable is used as an explanatory variable, a consistent estimator for the regression slope can be obtained from the ordinary least squares method. A consistent estimator of the correlation coefficient is then obtained by multiplying the regression slope estimator by the variance ratio of the two variables...
February 27, 2017: Statistics in Medicine
https://www.readbyqxmd.com/read/28239886/fibrocartilaginous-mesenchymoma-of-bone-a-single-institution-experience-with-molecular-investigations-and-a-review-of-the-literature
#7
M Gambarotti, A Righi, D Vanel, S Cocchi, S Benini, F M Elli, G Mantovani, P Ruggieri, S Boriani, D Donati, M Sbaraglia, A P Dei Tos, P Picci
AIMS: Fibrocartilaginous mesenchymoma is a rare intraosseous lesion with a total of 25 cases described in the literature. This study describes the clinical, radiological, and histological features of eight new cases of fibrocartilaginous mesenchymoma collected at a single institution between 1982 and 2016. The presence of GNAS and IDH1/2 mutations and MDM2 amplification was explored to evaluate possible links between fibrocartilaginous mesenchymoma, fibrous dysplasia, dedifferentiated chondrosarcoma, and low-grade osteosarcoma...
February 26, 2017: Histopathology
https://www.readbyqxmd.com/read/28239830/implant-survival-and-success-rates-in-patients-with-risk-factors-results-from-a-long-term-retrospective-study-with-a-10-to-18-years-follow-up
#8
F De Angelis, P Papi, F Mencio, D Rosella, S Di Carlo, G Pompa
OBJECTIVE: Risk factors for implant therapy are represented by all general and local conditions that through various mechanisms can increase either short-term and long-term failure risk. The aim of this study is to assess the implant survival and implant success rates with single and multiple risk factors. PATIENTS AND METHODS: To address the research purpose, a retrospective cohort study was designed and implemented, including a sample of 225 patients with a total of 871 implants placed...
February 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28239785/pharmacological-analysis-of-the-therapeutic-effect-of-radioprotectors-cystamine-and-indralin-in-the-capacity-of-radiomitigators
#9
M V Vasin, I B Ushakov, V Yu Kovtun, S N Komarova, L A Semenova, A A Galkin, R V Afanas'ev, I V Bukhtiyarov
The therapeutic radiomitigating effect of cystamine and indralin was studied in experiments on mice and rats and pharmacological analysis of these drugs was carried out. The animals were subjected to whole-body (60)Co γ-irradiation. The mice were exposed to single (9-10 Gy) or double (8 Gy) irradiation with an interval of 1 month. The rats were exposed to 10 Gy with partial shielding of the upper quarter of the abdomen. In experiments on mice, pretreatment with reserpine abolished the therapeutic effect of cystamine administered repeatedly every 15 min over 1 h after irradiation...
February 27, 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28239775/changes-in-agonist-neural-drive-hypertrophy-and-pre-training-strength-all-contribute-to-the-individual-strength-gains-after-resistance-training
#10
Thomas G Balshaw, Garry J Massey, Thomas M Maden-Wilkinson, Antonio J Morales-Artacho, Alexandra McKeown, Clare L Appleby, Jonathan P Folland
PURPOSE: Whilst neural and morphological adaptations following resistance training (RT) have been investigated extensively at a group level, relatively little is known about the contribution of specific physiological mechanisms, or pre-training strength, to the individual changes in strength following training. This study investigated the contribution of multiple underpinning neural [agonist EMG (QEMGMVT), antagonist EMG (HEMGANTAG)] and morphological variables [total quadriceps volume (QUADSVOL), and muscle fascicle pennation angle (QUADSθ p)], as well as pre-training strength, to the individual changes in strength after 12 weeks of knee extensor RT...
February 26, 2017: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/28239771/can-training-change-attentional-breadth-failure-to-find-transfer-effects
#11
Lin Fang, Kristof Hoorelbeke, Lynn Bruyneel, Lies Notebaert, Colin MacLeod, Rudi De Raedt, Ernst H W Koster
Recently, there is increasing interest in the causal relationship between attentional breadth and emotion regulation. To test this causal relationship, attentional breadth needs to be manipulated stringently. The aim of the current research was to establish whether visual attentional breadth could be manipulated through experimental training procedures. We conducted two single-session training experiments and one multiple-session training experiment, all of which contained pre- and post-training assessments to test the direct transfer effects of training on attentional breadth construed in different measures...
February 26, 2017: Psychological Research
https://www.readbyqxmd.com/read/28239762/-1-h-13-c-and-15-n-backbone-chemical-shift-assignments-of-camelid-single-domain-antibodies-against-active-state-%C3%A2%C2%B5-opioid-receptor
#12
Remy Sounier, Yinshan Yang, Joanna Hagelberger, Sébastien Granier, Hélène Déméné
Nanobodies are single chain antibodies that have become a highly valuable and versatile tool for biomolecular and therapeutic research. One application field is the stabilization of active states of flexible proteins, among which G-protein coupled receptors represent a very important class of membrane proteins. Here we present the backbone and side-chain assignment of the (1)H, (13)C and (15)N resonances of Nb33 and Nb39, two nanobodies that recognize and stabilize the µ-opioid receptor to opioids in its active agonist-bound conformation...
February 26, 2017: Biomolecular NMR Assignments
https://www.readbyqxmd.com/read/28239759/primary-acquired-spondylodiscitis-shows-a-more-severe-course-than-spondylodiscitis-following-spine-surgery-a-single-center-retrospective-study-of-159-cases
#13
Anja Tschugg, Sara Lener, Sebastian Hartmann, Andreas Rietzler, Sabrina Neururer, Claudius Thomé
Spondylodiscitis may arise primarily via hematogenous spread or direct inoculation of virulent organisms during spine surgery. To date, no comparative data investigating the differences between primary and postoperative spondylodiscitis is available. Thus, the purpose of this retrospective study was to investigate differences between these two etiologies. One hundred fifty-nine patients that were treated at our department were included in the retrospective analysis. The patients were categorized into two groups based on the etiology of spondylodiscitis: group NS, primary spondylodiscitis without prior spinal surgery; group S, spondylodiscitis following spinal surgery...
February 27, 2017: Neurosurgical Review
https://www.readbyqxmd.com/read/28239737/splitting-methanol-on-ultra-thin-mgo-100-films-deposited-on-a-mo-substrate
#14
Zhenjun Song, Hu Xu
The dissociation reaction of methanol on metal-supported MgO(100) films has been studied by employing density functional theory calculations. As far as we know, the dissociation of a single methanol molecule over inert oxide insulators such as MgO has not yet been successfully realized without the introduction of defects or low coordinated atoms. By depositing ultra-thin oxide films on a Mo substrate, we have successfully proposed the dissociative state of methanol. The dissociation reaction is energetically exothermic and nearly barrierless...
February 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28239721/broad-scope-gold-i-catalysed-polyenyne-cyclisations-for-the-formation-of-up-to-four-carbon-carbon-bonds
#15
Zhouting Rong, Antonio M Echavarren
The polycyclisation of polyenynes catalyzed by gold(i) has been extended for the first time to the simultaneous formation of up to four carbon-carbon bonds, leading to steroid-like molecules with high stereoselectivity in a single step with low catalyst loadings. In addition to terminal alkynes, bromoalkynes can also be used as initiators of polyene cyclisations, giving rise to synthetically useful cyclic bromoalkenes.
February 27, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28239716/h-bonding-controls-the-emission-properties-of-functionalized-carbon-nano-dots
#16
Soumalya Mukherjee, Edamana Prasad, Anju Chadha
Bathochromic and hypsochromic shifts in the photo-luminescent spectra of doped and functionalized carbon nano-dots (CDs) arise due to the complex interaction between CDs and the solvent molecules around them. Nitrogen-functionalized carbon nano-dots (N-CDs) were synthesized from citric acid and urea using microwave assisted hydrothermal methods. Optical studies (absorption and photoluminescence) from the as-synthesized N-CDs were carried out in polar protic, aprotic and non-polar solvents. When excited at 355 nm, blue photoluminescence (PL) was observed from the N-CDs dispersed in polar aprotic solvents while green emission was observed in polar protic solvents...
February 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28239705/chemical-communication-and-dynamics-of-droplet-emulsions-in-networks-of-belousov-zhabotinsky-micro-oscillators-produced-by-microfluidics
#17
Kristian Torbensen, Federico Rossi, Sandra Ristori, Ali Abou-Hassan
Chemical communication leading to synchronization and collective behaviour of dynamic elements, such as cell colonies, is a widespread phenomenon with biological, physical and chemical importance. Such synchronization between elements proceeds via chemical communication by emmision, interdiffusion and reception of specific messenger molecules. On a lab scale, these phenomena can be modeled by encapsulating an oscillating chemical reaction, which serves as a signal (information) sender/receiver element, inside microcompartments such as droplet emulsions, liposomes and polymersomes...
February 27, 2017: Lab on a Chip
https://www.readbyqxmd.com/read/28239692/high-throughput-screening-of-microchip-synthesized-genes-in-programmable-double-emulsion-droplets
#18
H F Chan, S Ma, J Tian, K W Leong
The rapid advances in synthetic biology and biotechnology are increasingly demanding high-throughput screening technology, such as screening of the functionalities of synthetic genes for optimization of protein expression. Compartmentalization of single cells in water-in-oil (W/O) emulsion droplets allows screening of a vast number of individualized assays, and recent advances in automated microfluidic devices further help realize the potential of droplet technology for high-throughput screening. However these single-emulsion droplets are incompatible with aqueous phase analysis and the inner droplet environment cannot easily communicate with the external phase...
February 27, 2017: Nanoscale
https://www.readbyqxmd.com/read/28239691/wood-combustion-particles-induce-adverse-effects-to-normal-and-diseased-airway-epithelia
#19
Manuel Krapf, Lisa Künzi, Sandrine Allenbach, Emily A Bruns, Ilaria Gavarini, Imad El-Haddad, Jay G Slowik, André S H Prévôt, Luka Drinovec, Griša Močnik, Lutz Dümbgen, Matthias Salathe, Nathalie Baumlin, Constantinos Sioutas, Urs Baltensperger, Josef Dommen, Marianne Geiser
Residential wood burning is a major source of poorly characterized, deleterious particulate matter, whose composition and toxicity may vary with wood type, burning condition and photochemical age. The causative link between ambient wood particle constituents and observed adverse health effects is currently lacking. Here we investigate the relationship between chemical properties of primary and atmospherically aged wood combustion particles and acute toxicity in human airway epithelial cells. Emissions from a log wood burner were diluted and injected into a smog chamber for photochemical aging...
February 27, 2017: Environmental Science. Processes & Impacts
https://www.readbyqxmd.com/read/28239661/klf2-and-klf4-control-endothelial-identity-and-vascular-integrity
#20
Panjamaporn Sangwung, Guangjin Zhou, Lalitha Nayak, E Ricky Chan, Sandeep Kumar, Dong-Won Kang, Rongli Zhang, Xudong Liao, Yuan Lu, Keiki Sugi, Hisashi Fujioka, Hong Shi, Stephanie D Lapping, Chandra C Ghosh, Sarah J Higgins, Samir M Parikh, Hanjoong Jo, Mukesh K Jain
Maintenance of vascular integrity in the adult animal is needed for survival, and it is critically dependent on the endothelial lining, which controls barrier function, blood fluidity, and flow dynamics. However, nodal regulators that coordinate endothelial identity and function in the adult animal remain poorly characterized. Here, we show that endothelial KLF2 and KLF4 control a large segment of the endothelial transcriptome, thereby affecting virtually all key endothelial functions. Inducible endothelial-specific deletion of Klf2 and/or Klf4 reveals that a single allele of either gene is sufficient for survival, but absence of both (EC-DKO) results in acute death from myocardial infarction, heart failure, and stroke...
February 23, 2017: JCI Insight
keyword
keyword
43881
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"