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Pancreas trasplantation

Daniel Casanova
In December 1966, the first pancreas transplant ever was performed at the University of Minnesota. R. Lillehei and W. Kelly, transplanted a kidney and a pancreas in a diabetic patient on dialysis, getting function of both organs. Since then, the technical and immunological advances in this transplant have resulted in graft and patient survival results as the rest of the abdominal solid organ transplants. The balance of these 50 years is that more than 50,000 diabetic patients have been transplanted in more than 200 centers around the world...
May 2017: Cirugía Española
Massimo Venturini, Claudio Sallemi, Caterina Colantoni, Giulia Agostini, Gianpaolo Balzano, Antonio Esposito, Antonio Secchi, Francesco De Cobelli, Massimo Falconi, Lorenzo Piemonti, Paola Maffi, Alessandro Del Maschio
OBJECTIVE: Islet allotransplantation is a less invasive alternative to surgical pancreas transplantation for Type 1 diabetes, while percutaneous intraportal islet autotransplantation (PIPIAT) is usually performed after pancreatic surgery to prevent diabetes. Our aim was to assess the feasibility, radiological aspects, complications and clinical outcome of PIPIAT following pancreatic surgery for not only chronic pancreatitis but also benign and malignant nodules. METHODS: From 2008 to 2012, 41 patients were enrolled for PIPIAT 12-48 h after pancreatic surgery (extended pancreatic surgery for chronic pancreatitis and benign/malignant neoplasms)...
August 2016: British Journal of Radiology
María J Ricart, Frederic Oppenheimer, Amado Andrés, José M Morales, Angel Álonso, Constantino Fernández
BACKGROUND: Our objective was to describe efficacy and safety of enteric-coated mycophenolate sodium (EC-MPS) in de novo and maintenance recipients of kidney-pancreas transplant in the clinical practice. METHODS: Observational, multicentre, prospective, 12-month study. RESULTS: We included 24 de novo and 24 maintenance patients. EC-MPS mean (± SD) doses at initiation in de novo patients were 1440 ± 0 vs. 1268 ± 263 mg/d at month 12 (M12)...
May 2012: Clinical Transplantation
C Ricordi, V Mazzeferro, A Casavilla, C Scotti, A Pinna, A Tzakis, T E Starzl
The outcome of human islet isolation procedures can be significantly effected by the technique used for pancreas procurement. In fact, the final step of islet purification using discontinuous density gradients requires a significant difference between the density of the islets and the density of the non-endocrine component of the gland. Therefore, any procedure during multi-organ procurement that will result in edema or degranulation of the acinar tissue will result in failure of the islet purification step...
1992: Diabetes, Nutrition & Metabolism
A Ríos, C Conesa, P Ramírez, P J Galindo, J M Rodríguez, M M Rodríguez, L Martínez, P Parrilla
OBJECTIVE: Our aim was to analyze acceptance of cadaveric and living organ donation for transplantation among resident doctors, given that they are the new professionals of medicine who will have to encourage and develop transplant programs. MATERIALS AND METHODS: A random survey was performed on resident doctors in a third-level hospital with an organ transplant program which is accredited for undergraduate and postgraduate education (n = 171). Attitudes toward cadaveric and living donation were evaluated using a questionnaire including various psychosocial variables that might affect such attitudes...
April 2006: Transplantation Proceedings
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